r v THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA PRESENTED BY PROF. CHARLES A. KOFOID AND MRS. PRUDENCE W. KOFOID ^ TEEATISE ON THE HISTORY, ETIOLOGY AND PROPHYLAXIS. BY JOHN M. WATSON, M. D., PROFESSOR OF OBSTETRICS AND THE DISEASES OF WOMEN AND CHILDREN, IN THE MKDICAI DEPARTMENT OF THE UNIVERSITY OF NASHVILLE. THIRD EDITIOU. NASHVILLE, TENN. : E. Q. EA3TMAN & CO., PRINTERS, UNION AND AMERICAN BLOCK 1859. TO JAMES E. WENDEL, M. D., This Volume IS MOST KINDLY AND RESPECTFULLY INSCRIBED, IN HIGH CONSIDERATION OF His Great Professional Attainments, Practical Skill, and; Sterling: Qualities, Closely tested by the Author during ten years association with him, as a co-partner in the practice of Medicine. M35$6m PREFACE. It is scarcely expected that in this age of book-making, an author should stop to apologize for publishing his work, jet it may not be amiss to make a few statements in regard to the one now about to be offered to the professional public. This monograph was first published in a series of numbers in the Nashville Journal of Medicine and Surgery. It was then well received by the profession, and favorably reviewed. Shortly after appearing in the aforesaid Journal, it was published a second time, in a pamphlet form. The work" in its present, or third edition, will be greatly enlarged, and will contain two costly original plates, and consist of about eighty pages neatly and substantially bound in one volume. The author has just cause to hope that it will again meet with a kind reception by the profession, especially as he is not aware that any regular monograph has ever been pub- lished on the fatal malady of which this treats, a reason which he may offer as a further apology for the present one. Trismus Nascentium, or Lock- J aw of Infants, is no uncommon disease, but one which is constantly occurring in our midst. No condition or habits of life, peculiarity of 'climate or race, give immunities from its attacks. The umbilical cord must of necessity separate from its vital VI. PREFACE. connections with the umbilicus, either by a healthy or a diseased action, and to show how the latter may be counter- acted, and tetanus thereby prevented, constitutes the main design of the writer. The physiology of the separation of the cord has been studied only by a few, while its pathology has been almost disregarded ! Even the special anatomy of the umbilicus of the infant has by no means received the attention and consideration which it so justly deserves. The parts which enter into the formation of the infantile umbilicus are, of course known and described by anatomists, but neither their physiological nor pathological changes, which they undergo while the cord is separating, are studied or regarded by the practitioner as they should be, especially that diseased state of the parts which is so apt to excite infantile tetanus. The funis with its membraneous covering, its gelatine two arteries and vein may desiccate Kindly, and separate from its connections with the umbilical ring without irritation, inflam- mation, suppuration, or sloughing. After which the navel may contract and close up without disease of any kind what- ever ; but we are bound to admit that there is often a failure in this remarkable physiology, and that the parts are greatly disposed, all this time to pass into a diseased state which may produce the lock-jaw of infants. Even if the cord come away without leaving any obvious appearances of inflamma- tion and irritation, though imperceptible, they may follow and even produce the fatal malady ! Hence, the special anatomy, peculiar physiology, and dangerous pathology of these parts should be studied both by students and practitioners with PREFACE. TO great care. The writer has therefore, been at great pains in getting up a colored plate of this hitherto neglected anatomy; and also another representing very finely the patho-phjsiog- nomy of infantile tetanus. These two original plates will add greatly to the value of the work. The author is not aware that any of this kind has been heretofore pub- lished. Could the tetanus of adults be as often traced to any par- ticular part as that of infants can, and were such a part as constantly liable to pass into a morbid state at a particular time, as is the umbilicus of the child, its special anatomy, morbid changes, and time of liability thereunto, would be most accurately and minutely described, demonstrated, and studied with a careful regard to its great importance. Why less important on the part of the infant? -Merely because it is not generally understood and appreciated. I do not by any means charge the profession with a disregard of infantile life, but insist that this constant, palpable source of a great mortality among infants is not regarded by many as it evi- dently should be. If the real source of this mortality was generally known and appreciated, it would doubtless receive as much careful attention as if it appertained to adults. Besides, the profession has done much by writing and otherwise for the elucidation and cure of infantile diseases. Hence, it is more astonishing that the chief cause of this dreadful and fatal disease has not been more generally admit- ted, and proper and timely measures employed to counteract it. This failure has been highly prejudicial to the safety of infants wherever it has prevailed; for a thorough conviction Vlli. PREFACE. of the true cause of this mortal, affection would have secured to them a sure prophylaxis. The notion, so fatal to many infants, that Trismus Nascen- tium is an undefined, nervous disorder, having its source in a variety of imaginary causes, differing radically in its patho- logy from the lock-jaw of adults, has prevented many from giving the navels of children the protection which they so justly deserve at our hands. Much praise should be awarded to those writers who have called the attention of practitioners to that morbid state of the child's navel which produces ihe tetanus of infants, showing that it is only an infantile modi- fication of the traumatic lock-jaw of adults. But as they have not presented and insisted on the only reliable prophylaxis, I feel that I am justifiable in publishing, this volume, in order that I may, if possible, direct the attention of practitioners to, and a solicitous regard for, the state of the navel, pending the first two weeks of infantile life. If proper measures be then employed, children will escape this disease. Besides, those writers who have incidentally written on this subject, have also written about many Other things in the same work — things which are generally more regarded than the one which I am now trying to bring forward, in all its exclusive, weighty importance, more prominently before the profession. Although we cannot cure this disease after it is developed, yet we can prevent it. We may not be able to expel the enemy after he has entered the house, yet in this instance we may bar the door most effectually against him. A preven- tion will, however, require on the part of the practitioner a thorough conviction of the truth that, this hopeless malady PREFACE. IX. originates in a diseased condition of the umbilicus, and great and unremitting care on his part to prevent this state from coming on, or if it should, to mollify and change it, during the first eight or ten days of early life. The writer has always been very forward to employ proper means to prevent a diseased action of the umbilicus during the separation of the funis and a few days afterwards ; and also for its subdual when it occurred. He finds in his inter- course with practitioners, that he has uniformly on his part given more attention to these things than any physician with whom he has conversed on the subject. He, therefore, feels very confident that his great and constant care has given his patients immunity from this much dreaded malady. He has never had a case to occur in his very extensive practice in an infant of which he had the management! This remark was made by him eight years ago, when this treatise was first pub- lished ; and he is now happy in not having, in any way, to qualify it. May he not then, most truthfully say that pre- vention is better than cure. To prevent the occurrence of a disease is much better, in every sense, than to relieve it after it has occurred, were it in our power to do so, but when we think of its incurability, the prophylactic treatment rises, in our estimation above all other considerations. Were it even occasionally curable, the great suffering of the little patient, its doubtful condition, the maternal anxieties, so acutely felt at such times,, are enough to excite our greatest professional efforts to prevent it. There is more professional good and disinterested conduct practiced in preventing, than in curing a disease after it has X. PREFACE. developed: much "suffering, valuable time, painful anxiety and needful fees are saved in that way. The immense and incal- culable amount which has been done by Prophulaktikos, from the prevention of small-pox down to that of a bad cold, cannot possibly fail to impress the mind of the reader with the importance of this subject. The hand, though it be scarcely seen, which from moral motives, or by professional skill, wards off an impending evil, deserves far more praise than the one that, even amidst professional glare cures It after it has come. But the statesman who by his well-timed policy prevents a war, never acquires the renown of a hero who successfully fights the battles of one. So with the doc- tor ! Yet there are exceptions in both cases. Dr. Jenner gained a greater renown by his wonderful prophylaxis against small-pox than any have done by treating it. Although sani- tary measures, from quarantine regulations down to fastidious teaching about diet and dress, have been much insisted on, yet for the want of a proper respect for them, they have often failed to do good. It is very difficult to direct the pub- lic mind in the proper ,way of prophylaxis. Hence the great neglect of vaccination, the greatest boon which has ever been conferred on mankind by scientific medicine. In these fast times many are willing to run the risk of small-pox rather than stop to vaccinate ! The public mind does not seem to appreciate preventives, and they are often regarded as useless hindrances ! How can I then hope for the employment of my prophylactic ? What practitioner will, in his professional hurry, stop long enough to manage the infantile umbilicus as he should ? Few I fear ! Yet this painful consideration does PREFACE. XI. not annul the obligations I am under to the profession and to parents to point it out, and insist on its employment. It is not for the want of professional magnanimity that these are not employed ; for there is enough to prevent all diseases were it practicable, either by our administration of them, or by a general adoption of them by the people. It is not of this that I complain. It is of too much indifference about those already known, both to physicians and communi- ties, especially of those which may be deemed minor ones. These have lost their great importance, both in professional estimation and general regard. Physicians have written much on this topic, indeed, much in point, but they have not been heeded : those in health will not stop to learn prophylactics from the doctor, nor to employ them when advised. Such essays have not been written in a manner to impress the public mind with their value, nor do physicians themselves stop to advise and insist on them as they should. We want a modern work on this sub- ject ; few only read old books. The improvements of our times are so great, that many suppose things written centuries ago can possess but little value. Hence, this important sub- ject must, so to speak, be re-taken in hand, by some good and efficient writer, and re-written for the present time, and thereby fully adapted to the spirit, taste, and general course of things before it will be regarded as it should be. I there- fore must be excused for trying, so zealously, to adapt the one under consideration to this state of things. I will now remind the reader that my prophylactic has for its object the mother's chief concern, her babe: which is to her a Xll. PREFACE. moral, oblivious anodyne, causing her to forget her past suf- ferings; and is also the incarnation of her maternal hopes, her puerperal joys and prospective delights which take the "ways of many agreeable and encouraging fancies. This, her reward and compensation for so much solicitude and suffering, must be protected, whereby her maternity may be preserved. Without this living joy, what will become of her? In her puerperal state she sustains not only a peculiar physical rela- tion to her offspring, which differs from all others, but also a sublime moral one, which also has its peculiarities in her early confinement. At this time she becomes almost one with "her child. So many of her moral and physical feelings concenter in it that she feels she could not hope and live without it! "A new center exists, the cradle^ around which every thing revolves. The milky age, the supreme innocence of the little one, throws its spell over all. Compassion and tenderness enslave the family to him. The father serves the mother, and the mother the child. It is seemingly a world, ordered not like the outer world, but according to the law of love, and of God ; in it the strong wait on the weak ; domin- ion belongs to the least." The mother will do her part, and shall the doctor fail to perform his ? If he through his neglect let the child die, she may die. This tender vine entwines itself so closely around the maternal heart, pene- trating it at every point with its prehensile embraces that it cannot be removed without deep, dangerous lacerations. Thus would her puerperal convalescence be retarded or decline into disease ; and how acutely painful would be the remembrance of her past travail ! Says one, just in point PREFACE. Xlll. here : " I have tears in my heart, and for more than one thing. I have not passed (in history) the Styx, the river of the dead, so many times with impunity. I am not insensible to my times, and I feel their mortal wounds. Woll, all this, which should deaden me to private sorrows, leaves a place in my heart plainly bleeding for what I have beheld so often, the mother separated suddenly from her child." When the death of the infant occurs from Trismus it most commonly occurs about the eighth, tenth, or twelfth day of the mother's confinement. May I not say that this is the very worst time for her to meet with such a trying calamity ? She has just had time enough to forget her sorrows for joy that a child is born unto her, and to place all her maternal affection on her child ; and a little sore on the nav r el has killed it ! which the doctor might have prevented by a timely employment of the prophylactic under consideration. Should the like occur to any physician, knowing that it might have been prevented by proper attention to the umbilicus, how shall he deal afterwards with his conscience and the mother's sorrow? Not by telling her that it could have been pre- vented, nor that it occurred by his neglect. That would increase her grief and ruin his professional character with the family. Fortunately, in one sense, mothers and families are ignorant of this means of protecting the lives of infants; but we hope the time will come when they will be well informed on this subject, and require of their attendants a faithful employment of this prophylactic, even if the attend- ing physician should, from a wrong theory, abjure it. At the present time many infants perish of this disease, that have .XIV. PREFACE. received no protecting treatment from the physicians who attended their mothers. Great, indeed, would be their self- reproach were they fully aware of the dreadful consequences of such neglect. No theory whatever of the cause of Trismus should excuse him for neglect of the child's umbilicus. When physicians and nurses shall be constrained by prac- tical results to pay proper attention to the umbilicus, then but few if any children will die of Trismus. Then the great object of this work will be accomplished. The reader must bear with my great earnestness ; no luke- warm expressions, no cold declarations, however truthful and much in point, will suffice. For I feel that I should not only state facts, but enforce them, also, by associating them with the moral considerations which should constrain us to regard them as duties incumbent on us, not only professionally, but conscientiously. When our moral feelings are properly awakened under impressive truths, we shall scarcely fail to perform the duties which they enjoin on our hands and bind on our consciences ! Let the physician only look at the painful scenes of infantile death in the puerperal room, with its moral and physical influence on the bereaved mother, the sorrow of the father, and the general distress of the family, resulting from a neglect of his duty, or that of another, and he cannot fail to appreciate the weighty subject now under consideration. These are no idle fancies, for scenes' of this kind, enough, forsooth, to move the heart of stone, often occur ! It is well said, that he who disregards truth in little things is very apt to not regard it in great things, PREFACE. .XV. i Nothing should be professionally small which contains a grain of practical truth, especially when infantile life may be bound up with it. Things may be small in them- selves, and yet capable of producing great results. The hand which in judgment and compassion turns the child aside from the viper, may save life by the simple act, while the one which is withheld may destroy life. Thus we see that' both positive and negative evils, however great in them- selves, may be occasioned by very little things. Thus I have labored to raise my prophylactics prospec- tively, in the estimation of the reader, that he may not un- dervalue them because they may, in ignorance, be called little things. After all, did these simple means, called in a this treatise prophylactics, require great mental effort to obtain a know- ledge of them, great surgical or clinical tact to employ them, and great confidence to admit of their employment, they would be more highly respected and more constantly practiced. As they are capable of doing as much or even more general good than if they were of the character just stated, why should they not, in point of utility, at least, be equally respected and as constantly employed ? No good reason can be assigned. Professional pride may murmur and hint that it cannot stoop to such little things. He who can- not stoop professionally to save life, can never stand consci- entiously erect in his profession. It is a profession which has much to do with the conscience of the practitioner as well as with the lives of patients. Hence, nothing in the estimation of the true physician can be small which secures XVI. PREFACE. life. Lastly — can anything however apparently little in itself, be considered trifling or small in the esti- mation of a bereaved family, which they knew would have saved the life of the child that was destroyed by tetanus the day before ? Our negative answer here should bind us to our duty, which we should constantly perform though it may lead us in the way of little things, as some in the blindness of professional pride have termed them. Pride constantly stands in the way of the performance of some of our greatest duties, and often requires for its correction and subdual, the exercise of great moral courage. And he who has not a sufficient amount thereof firmly and indignantly to meet the taunts and jeers of the ignorant or the proud in regard to his means of saving life, is not worthy of the confidence of any community. Let the young practitioner not be afraid or ashamed to employ useful prophylactics, let them be regarded in whatever light they may be by others. TRISMUS NASCENTIUM, ITS HISTORY, ETIOLOGY AND PROPHYLAXIS. This great outlet of infantile life has not received that notice and investigation from our best writers, which its great importance so justly merits:- — some passing it by in reprehensible silence, have written copiously enough on other opprobia medicorum, while others have given us only a few formal pages or paragraphs on a subject which required at their hands a most elaborate treatise. All that has been published about this fatal malady, is, for the rqpst part, well calculated to embarrass and disappoint the reader — leaving him uninformed of its history, in doubt about its etiology, and uninstructed in a reliable prophylaxis — not remedy, for there is none ! Moschion, who wrote a manual of midwifery about the end of the first century, entertained an opinion vaguely correct in regard to the exciting cause of this disease ; so did Levret. They thought that the stagnant blood in the umbilical cord might produce dangerous disease ; probably they had seen this malady consequent upon inflammation and irritation of the navel. M. Bajon also concurred in this opinion, distinctly regarding a pathological condition of the umbilicus as the cause of this affection — a view which Dr. Colles has very nearly confirmed by his. dissec- tions and observations. It has, however, been attributed to very different causes by Evans, Bartram, Clark, Under- wood, Labatt and others. Hence, we meet with a great contrariety of opinion, as expressed by those writers — all disagreeing in their etiological expositions, indeed, so much so, as greatly to impair our confidence in their writings. Dr. Cullen, a copious writer on other subjects, has treated the one under consideration with great brevity ; conscious of his apparent neglect, he says apologetically : " It is a disease that has been almost constantly fatal, and this, also, commonly in the course of a. few days. The women are so much persuaded of its inevitable fatality, that they seldom or ever call for the assistance of our art. This has occasioned our being little acquainted with the history of the disease, or with the effects of remedies in it." But this is not the secret ; physicians had seen this disease often enough, but did not understand it ; they had also treated it, but had not cured it ; had sought out its cause and pathology, but had not found them ; hence, forsooth, so many writers have avoided the great difficulties involved in its obscure history, controverted etiology, unknown pathology and intractable course. Colley, Condie, Church- hill, and others, though greatly skilled in eclecticism, have gathered but little valuable or satisfactory information from the writings of others on this subject. Journalists, know- ing that systematic writers have failed to account for the phenomena of this disease, and being unrestrained by any known facts, have propagated, and vainly attempted, by reporting cases, to prove, many fanciful and untenable conjectures. To a particular instance of this kind, I will now refer : Dr. J. Marion Sims, of Montgomery, Alabama, has pub- lished in the Medical Journal of the Medical Sciences some interesting "Observations on Trismus Nascentium, with cases illustrating its etiology and treatment." From all of which he deduces the following strange and unwarrant- able conclusions : " That Trismus Nascentium is a disease of centric origin, depending upon a mechanical pressure, exerted on the medulla oblongata and its nerves ; that this pressure is the result, most generally, of an inward dis- placement of the occipital bone, often very perceptible, but sometimes so slight as to be detected with difficulty ; that this displaced condition of the occiput is one of the fixed physiological laws of the parturient state ; that when it persits for any length of time after birth, it becomes a pathological condition, capable of producing all the symp- toms of Trismus Nascentium, which are instantly relieved simply by rectifying this abnormal displacement, and there- by removing the pressure from the base of the brain." I have made this lengthy quotation in justice to Dr. Sims, as I intend to make some critical remarks on his observations, cases and conclusions. I will endeavor to do this fairly at least, yet faithfully His strange views, wonderful practice, and doubtful cases, require a very rigid examination \ which, when fairly and faithfully made, may seem a little severe; therefore, I will here remark, that nothing like.wanton severity is intended ; on the contrary, I am ready to acknowledge his merits as an independent thinker and actor, by which, great difficulties have some- times been overcome, at other times signal failures have ensued. The latter sequence has followed in the present instance. The Doctor has failed in his commendable enter- prise ; but his failure is a splendid one ! Had he succeeded in directing one ray of light into the deep, dark plasis of this mortifer morbus, he would have merited the everlast- ing gratitude of the profession. Signal as his failure has been, judging from his writings, he does not seem to be conscious of it; but on the contrary, contends that he has succeeded in finding out the etiology of this disease, and for it, also a remedy ! The occasional displacement of the cranial bones is a subject to which the attention of prac- titioners of medicine should be directed ; but while we feel under great obligations to Dr. Sims for calling our atten- tion to this source of disease, we are far from admitting that it is ever a cause of Trismus, be it the source of what- ever other affections it may. The Doctor has investigated this subject according to the following ■" fixed ideas :" 1. Dorsal decubitus; 2. Oc- cipital depression ; 3. Trismus Nascentium ; 4. Chang* of position; 5. Recovery. These five things always obtain in the mind of Dr. S. whether they do in his patients or not ; when, for instance, they cannot be seen *by other physicians, he seems to recognize them none the less clear- ly, as we shall discover presently. His case the II presents the following particulars : The patient had been ill of Trismus Nascentium two days — the attending physician, had declared that the disease was in- flammation of the brain, and that death was inevitable — there were frequent spasms — mouth closed tightly — swal- lowing impossible — the back of the head sunk in. A change of position was made, which in four hours gave relief, and in eighteen hours cured the disease ! All this was done, too, without the aid of homoeopathy, hydropathy, or mysticism of any kind. pathetism, where wert thou ! In this case the depressed occiput was relieved by a mere change of position, and the patient cured in eighteen hours. How shall we reconcile these statements ? A case of Trismus Nascentium, presenting the foregoing array of symptoms, of two days continuance — the patient just ready to die, and then cured by a mere change of position in eighteen hours ! To the credit of Dr. Sims I will here state that this case was obtained from a non-medical correspondent ; although he has endorsed it, yet I am willing he should have all the benefit of the foregoing fact. The very next case, however, is both marvelous and in- consistent, although reported by the Doctor himself: The child " was born trismal," had had the disease thirty-six hours when seen by him, then by his magic change of posi- tion was cured in two hours ! His statements in case the IV, in regard to the symptom of the child's inability to suck, do not accord with my own observations. " This inability to sack,'' says he, "is path- ognomonic of the disease." This symptom does not always exist in the tetanus of children, especially in that variety termed chronic : this inability to swallow may be absent just as it is sometimes in the tetanus of adults. I have seen fatal cases of infantile tetanus, when the symptom of 8 trismus did not obtain — there was rather a disinclination than an inability to suck. But if he supposes that the mere symptom of trismus constitutes the whole of the disease, then is he correct in saying that u an inability to suck is pathognomonic of the disease." Let his views be what they may in this respect, there would be no less im- propriety in saying that the varieties of the opisthotonos and emprosthotonos are not tetanus in the strict sense of that term, than to conclude that trismus, another variety, is not. This reminds me of Dr. Cullen's acknowledgment : " I have in my nosology put the trismus or locked jaw, as a genus distinct from the tetanus ; all this, however, I now judge to be improper, and am of opinion, that all the gen- eral terms mentioned denote and are only applicable to different degrees of one and the same disease." Surely trismus in the infant or adult, is a mere variety of tetanus, and like the other varieties depend upon a pathological condition of some of the cerebro-spinal centres. It is a great misfortune that the term trismus nascentium was ever adopted \ tetanus nascentium would have been a better, though a less euphonious one. There was no great- er necessity for changing the name of this disease in the case of infants than there is to change that of pneumonia, dysentery, or colic, when they attack children. We had just as well term tetanus, trismus adultorum, trismus viro- rum, or trismus feminarum, as to call it trismus nascenti- um. In the employment of these terms, that of tetanus, would be kept too much in the back ground, as it really has been, by the use of the term trismus nascentium. Like Dr. Sims, we may lose sight of the true character of a tetano — pathological condition of some portion of the cerebro-spinal column, which in every instance is the prox- imate cause of the disease ; and which cannot be relieved in a moment in any instance, and often not at all, by a mere removal of the exciting cause. This every careful observer knows ; but more of this presently. I will now examine case the V, being the most remark- able the Doctor ever saw. This case was reported in part by a Dr. Vickers, though seen and commented on by Dr. S. himself. The child was four or five months old' — had been sick all its life — the occipital bone was shoved in to an almost incredible extent — it had trismal symptoms, ac- cording to his estimation of them, which were completely under the control of the Doctors ; they were relieved and reproduced at pleasure by simply rectifying and displacing the occiput. This was done according to Dr. Sims' pre- vious proposition, " That the symptoms of Trismus Na~ scentium are instantly relieved by simply rectifying the abnormal displacement of the occipital bone." This is one of his propositions deduced from his cases and observations, and put down in his treatise in all due form. Who except Dr. Sims could thus have hooked the Levi- athan, and led the monster to and fro with such trismal docility ! No one, alas ! Surely he had only the pliant dolphin clonus with which to deal, and not the crooked serpent tetanus. That alternate displacement and replace- ment of the occiput should suspend and reproduce some particular forms of paralysis, or nervous affections, I an i prepared to admit ; but that trismus, after being established for days, or even hours, should be thus dealt with, is more- 10 than any physician who clearly distinguishes this disease from other nervous disorders, can allow, in my humble judgment. The symptoms of trismus may be excited — not cured — by rubbing the epigastrium, which I have my- self often done in obscure cases, to develop the symptoms more fully ; afterwards there would be a reduction of the former symptoms, from the expenditure of nervous excita- bility. The same occurred also, I presume, in the Doctor's cases of nervous disorders, by raising and depressing the cranial bones. I shall not follow Dr. Sims through his trismoid cases, as he terms them ; those already mentioned are surely tris- moid enough, in that diminutive sense, so much so in- deed, that even such a term is too strong for them. Be- sides, I did not intend to review his writings in a regular way, yet there are a few things connected with these tris- moid cases, which I will notice. Dr. S. has reported but one case of cadaveric autopsy, and strange to relate, this does not contain a single word about lesion of the brain or meninges, from a long contin- ued displacement of the cranial bones — only that the u brain was perfectly bloodless" — no signs of previous con- gestion, irritation or inflammation. When the Doctor could not make out a case of dorsal decubitus and depression of the occipital bone, still cling- ing to his fixed idea, or cherished theory, he learned that the child had been nursed on its side, and that lateral, or rather diagonal decubitus had produced a depression of a pariental bone, and laying hold of this opportune succeda- 11 neuin, he maintains his views with as much confidence as before. If any thing was still wanting to show that Dr. S. does not appreciate the danger and mortality of this dreadful disease, I might advert to his notions about the operation of laryngotomy affording relief until it could be cured. I will not, however, detain the reader longer with any further critical remarks on this subject, but advise him to read the treatise for himself, which he may find in the American Journal of the Medical Sciences, in April number, 1846, and in July and October numbers of 1848. If any fur- ther apology be necessary for these strictures it may be found in the remark, that Dr. S.'s theory, cases and treat- ment are all well calculated to mislead the inexperienced and divert their minds from the true sources .of tetanus, and also from the only means by which infants can be pro- tected against an often occuring and incurable malady. I will now take my leave of the Doctor in ihe words of Petrarch: "Raro magni errores nisi ex magnis ingeniis prodiere. Etiology. — The causes of Trismus Nascentium with their attendant difficulties, like every thing else pertaining to this perplexing malady, have been very much neglected : indeed, I am not aware that any writer has arranged them according to their proper relation to each other, or their usual division in other diseases. Its predisponent, exciting, and proximate causes have often been confounded with each other — one writer mistaking the predisponent for the exciting cause, and another, the latter for the former. It 12 will be readily conceded that these causes occasionally change their relation to each other, but this is very differ- ent from confounding them with each other in particular instances. While treating this subject according to the foregoing division, I shall have occasionally to introduce other causes in their proper places, such as accidental, ac- cessory, &c. It will be necessary to make a clear distinction between the predisponent cause and the habit of body or diathesis, which constitutes the predisposition itself. Two persons, for instance, may be exposed to the same predisponent causes, and in one a predisposition to a particular disease may be produced by the yielding susceptibilities of his system, and be resisted by the opposing energies of the other ; or the same person may be affected by such causes at one period and escape their influences at another. Again, a predisposition to a disease may exist as. a connate diathesis. Then let a predisposition to tetanus be the effect of whatever predisponent causes it may, it must be regard- ed as a pathological state; which though occult and unap- preciable by any pathognomonic symptoms, yet it is doubt- less a tetanic element, capable of being developed by an exciting cause into plain, open, unmistakable symptoms of lock jaw, or of being subdued by a proper prophylaxis, which consists mainly in a protection from exciting causes. The agency of an exciting cause, however potent and ac- tive it may be, fails to produce the disease, when there is no existing predisposition, as may be illustrated by the fol- lowing examples : Two persons of the same age, sex, tem- perament and habits, breathing the same atmosphere, 13 receive similar wounds in corresponding situations ; one is attacked with tetanus, and the other escapes ; or, an indi- vidual receives a very bad wound and escapes lock jaw, and is afterwards attacked with it from a very slight wound. Such instances certainly show that the disease does not de- pend alone on an exciting cause. Again, the terminal points of wounded nerves may pass into a tetano-patholog- ical condition in a slight wound, and not in a far greater one, and vice versa. So, it is not the situation or size of a wound which determines an attack of this disease, but a peculiar occult state of the general system. This condi- tion may not, however, amount to a direct tetanic tenden- cy, but may be only a mere vitiation of the system that may interfere with the healthy healing of the wound, or the formation of a sound cicatrix; for the simple healing- over of a wound does not afford protection from an attack of this fatal malady, neither in infants nor adults. Then, any thing which impairs health in manhood or infancy may, in this general way act as a predisponent cause of tetanus ; but, 'there are some particular causes which evi- dently exert a more direct predisposing influence, such as cold, impure air, a damp, cold atmosphere, indigestion and high solar heat. And why may not malaria, itself, the frequent and great source of so many maladies, impress the system with a strong tetanic predisposition, by pro- ducing cerebro-spinal irritation, or irritation of some of the other great ganglionic nervous centres. This opinion is confirmed by the fact of Trismus having occurred so fre- quently in foul and badly ventilated lying-in-hospitals, and its occurrence having been prevented by improvements for 14 ventilation and cleanliness in such institutions, as, for in- stance, in the Dublin lying-in hospital. Dr. Joseph Clarke's account of this institution, in reference to the foregoing, is conclusive on this subject. The Exciting Cause of Tetanus Nascentium. — A trauma- tico-tetanic condition of the umbilicus is, with very few exceptions, the constant exciting cause of this disease. This part of my subject I shall now discuss at great length as it is paramount in importance to all others, in a prac- tical point of view. The analogy between traumatic tetanus, as it occurs in the adult and infant, is both stri- king and instructive, and well deserves our most particular consideration. In the adult, this disease generally comes on about the eighth or ninth day after the reception of a wound, and in the infant, it attacks so frequently on the ninth day after the cutting of the funis, that it has been termed "nine-day fits." That portion of the cord which, after its division is left in connection with the navel, is as liable to degenerate into an exciting cause of tetanus in the infant, as is a common wound in the adult. The beauti- ful physiological process of desiccation, contraction and separation of the cord so seldom occurs that it has been disregarded by many eminent writers. Even the great Baron Albert Yon Haller says : " Funiculi quidem ombili- calis particula quam obstetrics solent cum abdomine parvuli conjunctam relinquere abit in sphacelam, quassi ambusta et post biduum, triduumve dilabitur." This is certainly a good pathologcid, though by no means a physiological de- scription of the separation of the funis — a traumatic state 15 of things however, which frequently occurs. This over- sight has been committed also by other distinguished writers, namely, Chaussier, Beclard, Orfila, Capuron, and Dennis. C. M. Billard's explanation of the separation of the funis is quite satisfactory. He very properly maintains that u the desiccation of the cord is altogether a physiological phenomenon, belonging to the assemblage of vital phenom- enon, and entirely dependent on them. That part of the cord attached to the placenta does not exhibit the phenom- enon of desiccation, like the portion remaining with the child, but shrinks and decays like a dead substance, whilst the abdominal portion is not so affected. Here the desic- cation ceases as soon as life is extinct ; it either does not proceed in still-born children, or is considerably retarded. In place of drying and separating at the end of a few days, as is observed during life, the cord undergoes in the dead body a perfect decomposition, differing entirely from its normal desiccation." He further contends that the umbil- ical cord may, under favorable circumstances, separate from the navel, just as the stem of a cucurbitaceous fruit is sep- arated, or by what he terms "a proper suppuration." Of eighty-six infants examined by him, nineteen had red- ness and tumefaction of the umbilicus, without suppuration. The period of the detachment of the cord varies from the second to the seventh day. The infrequency of the healthy normal separation of the funis has not only been greatly overlooked by writers, but shows likewise how very liable infants are to irritaiton, in- flammation and sloughing of that portion of it which is left ' 16 at birth attached to the abdomen. This degeneration of a healthy vital action into a morbid, abnormal one, is easily induced by a great variety of causes, to all of which some children are more exposed than others, and among such tetanus is of far more frequent occurrence. These common causes among the blacks are bad dressings of the umbilicus, improper handling of the infant, wet and soiled dressings, which become alternately wet and dry for several days ; to •which may be added unsuitable applications to the naval itself after the detachment of the cord, that are more cal- culated to irritate and inflame the part, and in that way to provoke lock jaw, than to soothe, heal and prevent its supervention. As there is a much greater difference in the manage- ment, comforts and habits between white and black women after their confinement, than in their parturition, the causes which operate on the children of the latter, in occasioning a greater frequency of this disease among them, must occur after birth ; besides it is well known that the negro women generally have safer and easier labors than white women, as a consequence of their active, laborious habits. Hence, neither the imaginary- concussion of the spine during de- livery, nor the vaunted displacement of the occipital bone consequent upon dorsal decubitus, does account for the very great amount of numerical difference between the at- tacks of white and colored children. This difference must be occasioned by some particular causes, both predisponent and exciting, very different from those to which I have just adverted. I will now present an arrangement of facts, from which 17 an opinion of the utmost practical importance may be de- duced, in regard to the exciting eause of this disease — an opinion which when entertained must exert a salutary influence in checking the dreadful outbreaking of this intractable morbus. That this opinion may be embraced and have its proper practical influence, is one of the chief objects of the writer in contending for it so earnestly ; which is done not merely to confirm the fact as he believes, that a diseased umbilicus is the cause of infantile tetanus, but that a safe and easy prophylaxis may be established on a reliable basis, not to be overturned by a constant failure of the remedy in the hands of others, as has unfor- tunately been the case with most of those means prescribed by others in accordance with their peculiar theories. Their is, however, one just exception to this remark, which de- serves to be mentioned : Dr. Joseph Clark and others, re- garding badly ventilated lying-in hospitals, with their bad air and filthy apartments as causes of this malady, have done much good by their accordant prophylactic directions. For, although they mistook the predisposing for the ex^ citing cause, yet by directing that such causes should be avoided and corrected, the exciting cause, which is now so zealously contended for, though present and active in many instances, was in others greatly deprived of it* tetanic influence. Suppose Dr. Clark had said in regard to wounded patients in a hospital, that a vitiated atmosphere was the exciting cause of tetanus among them, and that their attacks of this disease were due to a state of the atmos- phere, and not their wounds. He could scarcely hare 2 18 committed a worse blunder than he has done by writing that tetanus was excited by bad air in the lying-in estab- lishment of which he had charge, instead of the tetanic condition of the navels of the children. That the Exciting Cause of this disease may 'be plainly seen and practically regarded, I will now set in order a number of facts, both in their proper relation to each other and their general bearing on its controverted points. From these, surely, a safe and useful conclusion may be easily deduced. By an arrangement of even dim lights in a proper manner, we may discern an object which could not otherwise be seen by them, so in the present instance by a proper collation of facts we may obtain a more correct view of the exciting cause of tetanus nascentium. The infant is no sooner born than it becomes a irau- matiaSy a trauma must of necessity be inflicted on its um- bilical cord ; a wound on a part which is, as has already been shown in the first part of this treatise, so very prone to pass into a pathological condition, and thereby excite irritation and inflammation of the umbilicus, that many eminent writers have overlooked its physiological excep- tions. With the brute mammalia, this artificial division of the cord is unnecessary, as theirs break according to an appropriate physical state ; then dry, contract and fall off without producing inflammation of their navels. Hence, though a species of the equus genus of animals is, as is well known, very liable to tetanus from wounds and other causes, yet no one, I presume, ever saw their foals suffering from the disease; as the horse is thus man's *?tf#w-congener, might we not expect to see them attacked 19 also occasionally with this disease I As adults and horses are, in this particular respect, pathologically congeneric, why should we suppose that their offspring are not so like- w ise ? It is quite reasonable to believe that they are, and that the immunity of colts from the disease is not owing to any connate difference of that kind, but to an exemption from its exciting cause — irritation and inflammation of their navels. The experiment of exciting artificial inflam- mation of the navels of the equinal young might shed some light on this subject. I will here remark that it is not contended that the bare wound on the part of the cord left attached to the child's abdomen, causes a pathological condition of that part, but the state itself of the part is such as to admit of an easy perversion of its normal pro- cess of separation, in which particular, it differs very much from the navel strings of other animals. The infantile umbilical cord, is too strong to be thus safely broken, and too full of the gelatine of Wharton to dry, contract and fall off in the equinal way ; it, therefore, requires some rational management. Really, it seems to have been de- signed by the Great Giver of mind, that the infant should not only receive instinctive, but likewise rational protec- tion at our hands. So, when their navel strings are man- aged in a rational way, they will not induce irritation nor inflammation of the umbilicus. It is necessary then that the cord should be cut, and other appliances be employed, of which I shall treat more fully presently. I must, how- ever, repeat 'that the navels of children, from bad manage- ment and other causes, often become inflamed, and it is a fact of no small consequence that negro children are far 20 more liable, to a variety of accidental or accessory causes^ which occasion irritation and inflammation of the umbili- cus, and it is well known that they are also more liable to tetanus. This liability to trismus is in a very remarkable degree proportionate to the liability to inflammation of the navel. So, in tracing out the exciting cause of this disease, it will be of great advantage to enquire very particularly into these accessory causes and their morbid influences on that part. By a proper examination and consideration of these advenient causes — nearly always occurring in the cases of negro infants — we may be able to answer the ap- propriate and important question, Why are the infants of our slaves more liable to tetanus than those of the whites ? This is indeed a strong question and much in point ; which when truthfully solved, its answer cannot be much short of a solution of the main problem. No one I presume will assume that the children of our negroes are more obnoxious to tetanus from a connate diathesis peculiar to the African race, than are the whites. An assumption of this kind may be refuted by stating the fact, that when the children of white parents, for instance, paupers, inmates of hospitals, &c, are subjected to the accidental causes which I shall presently relate, they, like the children of the blacks, are equally liable to trismus ; and moreover, when the latter are exempted from such things, they are no more obnoxious to the disease than the former. These facts are of too much importance to rest on mere assertion ; they must, hence, be sustained, for th^y contribute no liftle to the elucidation of our subject. I will now relate what must accord with the observations 21 of most physicians who have done much practice among negroes. When called to see their children we find their clothes wet around their hips, and often up to their arm pits, with urine ; smoking, fretting and kicking, the child is thus presented to us ; when, on examination, we find the umbilical dressings not only wet with urine, but soiled likewise with feces, freely giving off an offensive urinous and fecal odor, combined at times with a gangrenous fetor, arising from the decomposition— not desiccation — of the cord. May I not say, that a vital, physiological drying and separation of the funis under such circumstances is impossible ; hence the frequency of a pathological condition of the umbilicus in such cases, and I will add, the frequent occurrence of lock-jaw also among them. Moreover, these navel dressings are not only thus acted on by the child's urine and feces, but they also become impregnated with a filthy, irritating moisture, constantly exuding from the sphacelated cord ; there comes likewise an occasional inter- vening dry rough state of these foul deathful appliances, during which they rub, irritate and excoriate a surface al- ready excited by those foul agencies just mentioned. Nor is this all. Negro children are often improperly fed. and suffer from colic, and abdominal distention, causing them to fret, cry and kick, thereby producing abdominal movements well caclulated to bring umbilical dressings in rough contact with their navels. Their mothers never think of changing these hurtful dressings ; either from a want of changes, or a disinclination to do so, they let them re- main on — bandage and all — until the funis sloughs ; after this the applications are almost as hurtful as those pre- 22 viously employed — such as soot., dry dirt out of the back of the chimney, scorched cotton, greasy cloth folded up into a hard compress, and a bandage drawn around these with unmerciful tightness. That there are many excep- tions to this deplorable state of things, I readily admit ; so I might add, there are many exceptions to attacks of tetanus ; more indeed of the latter than the former, for every child that has a sore navel does not consequently have trismus. But more of this presently. I have enquired very particularly of the overseers of large plantations with numerous slaves, about the man- agement of their negro children, and in every instance where the mistress attended carefully to the dressing of the umbilicus, very few or no cases of trismus occurred. Mrs. P 1, a very motherly intelligent lady, informed me that she had raised about twenty little negroes, also, a goodly number of her own children, and that none horn on her place ever died of tetanus. She stated further that she always paid very strict attention to their navels, and in no instance trusted the management of them to their mothers. Now, it is worthy of remark, that Dr. Ii. has a quarter in sight of the place just mentioned, on which thirty or forty negroes constantly reside. This plan- tation has been for more than twenty years under the management of overseers ; one of them had the care of it fifteen years, during which period only two children died of lock-jaw; the next overseer was retained four years, daring which time four children were attacked and died of this disease; the third superintendent remained two years, in which time two deaths occurred from infantile 23 lock-jaw. The wife of the first overseer was an excellent nurse, and fully appreciated the danger of a sore navel. She paid careful attention to the navels of the little ne- groes, but her appropriate measures were sometimes de- feated by the carelessness of their mothers, during her absence from their houses. Yet, out of the great number of children born on this place in fifteen years, only two died of sore navel or its sequence, trismus. The wife of the next overseer was young, inexperienced and had no turn for attending to little negroes, so four died while she was there ; and the same may be said of the wife of the last mentioned superintendent, and the same result fol- lowed. In the last fifteen years, -Mr. B h has had fifteen color- ed infants born on his plantation, during which time, his mother, who was a midwife, resided on the same place, and paid great attention to the umbilk.il dressings, and not a single case of lock-jaw occurred while she lived ; she died a few years ago, and since her death but one negro child had been born on the place, and that died of sore navel and tetanus. Mrs. H e, a very intelligent and domestic lady has assured me that she has raised upwards of twenty little negroes on their plantation, and not one born on their place had ever been attacked with trismus — that she never in any case, trusted the navel of the child to the care of its mother, but always attended personally to its dressings. Mr. W n, who owns a number of slaves, told me, just after giving some directions about the management of the navel of a child whose mother I had just delivered, that 24 he had lost not less than twelve or thirteen little negroes from sore navel. This gentleman had the misfortune to lose his wife many years ago, and the care of the little children had been entrusted exclusively to their mothers. Whence, I ask, is this great difference of mortality in the two last examples? Many more illustrations of this kind might be reported but it is scarcely worth while to^ultiply them. Any one who is anxious to obtain additional information on this subject may do so by inquiring of the heads of other families, and they cannot fail to be impressed with the fact, that when physicians or intelligent nurses attend to the little negro children, cases of infantile lock-jaw are very rare ; so much so indeed, that a negative course in that respect towards them plainly, in its consequences, in- dicates the exciting cause of the disease. To conclude the present naration of facts, T will now introduce several com- munications on the subject, which I have lately received. The following extracts from a communication which I have just received from Dr. P. D. McCulloch, of this place, on the subject of Trismus Nascentium, will be read with interest by all who are disposed to investigate the phenom- ena of this dreadful pathos : " I have only investigated the cases which occurred in two large families, as they presented the largest number of deaths in proportion to the number of births among them. In the first family, comprising sixty or seventy blacks, there have been within the last eight years twenty births ; five of these died within the tenth day of their birth, and all of them with symptoms of Trismus, according to a re- 25 liable history of the cases. None of these received any attention from the white family until they had plain symp- toms of the disease. In only one of these cases was the umbilicus examined, in which the phenomena of well marked inflammation were present. I examined into the method usually pursued by the attendant with her navel-dressings, and found it had been the custom of the old negress, who always attended to the children, when the funis became partially detached, to remove it and dress the wound with common chimney soot. After this was ascertained, the lady of the farm attended to the children in a great mea- sure herself; since which time — three or four years ago — there has not been a case of the disease, although there has been a number of births since that period. It might not be amiss to add that four or five white children were born on this plantation during the above period, and that none of them were attacked with this disease. " In the second family, which contained about the same nnmber of whites and blacks, twenty or twenty-five chil- dren were born during the same period of time. Six of these children died of Trismus. The navels were examined in all these cases, and were found to be in an unhealthy condition in every instance. The dressings used on this farm were usually nothing more than a coarse domestic pad, placed over the severed funis, and bound down by a common bandage. The last of these cases occurred about four J ears ago ; from which time to the present the chil- dren born on this place have been strictly attended to by some of the white family, until they had passed the time 26 of an attack of this disease. No case occurred at any time among the white children on this plantation." Dr. M. Ransom, late of Texas, but now of our county, who resided some time on the Brasos, about thirty miles from Houston, has also kindly furnished me with some in- teresting facts, which I will now adduce : u According to your request, I send you a few notes on Trismus Nascentium, which I took during the summer of 1849, while in Texas. My information with regard to its occurrence here, until 1849, was obtained chiefly from intelligent citizens very capable of recognizing the disease- It was not observed here, as far as I can learn, until about 1845 or '46, since which time its prevalence has gradually increased every summer. Last year the mortality was very great from it, amounting in one or two instances to four-fifths of all the children born on some plantations, while on many others not one died. As a general rule, there has been either a very considerable mortality on a place, or none at all. The disease appears in about one- half of the families, and those families lose about one-half of their infants on an average. The number of deaths from this disease among white children is comparatively small. This malady is much more frequent in negro quar- ters than in families where the children are more directly under the supervision of white persons. It also prevails more extensively in the river bottoms, where the planta- tions are surrounded by dense forests, hung with moss, than in the prairies where the Gulf breezes are unobstruct- ed. It occurs, I may add, much more frequently in filthy, 27 ill-ventilated houses, than in clean, well aired ones, and is far more prevalent in summer than in winter. " I have never seen a case of Trismus where the umbil- icus was in a healthy condition ; it, on the contrary, was generally swollen, irritable and not suppurating. " I have never known a recovery from a well-marked case of this disease, except perhaps in a single instance ; which, if effected by any remedy, it was incisions over the swollen umbilicus. But this was tried at other times without the least success. "Nothing had been done by way of preventing this disease until this summer, except the occasional adminis- tration of small doses of calomel or castor oil for a week or two after the birth of the child. During the present summer many of the plantations have employed the means suggested by the above facts for its prevention. The ne- gro houses were freely ventilated, and the bedding and everything about their houses kept clean. The thick greasy musquito bar which was before allowed to hang around the bed, enclosing the woman and her child in a confined, impure atmosphere, was stripped off, and the pure air allowed to circulate freely around them. The nurse was directed to apply some stimulating ointment, such as red precipitate, or calomel to the navel, from the second day until, it was perfectly healed. When these prophylac- tics were properly attended to, they suffered very little from the disease ; while on other plantations, where they were neglected, it prevailed as extensively as it did the previous surnm*. I have had no opportunity of seeing 28 one of these preventives employed to the exclusion of the others ; hence, have no evidence that one is more efficacious than the other." Dr. Thomas C. Black, of our county, well known as a close observer of the phenomena of disease has obligingly furnished me with the following statements : u In reply to your inquiry about my opinion in the dis- ease usually called Trismus Nascentium, I can state that during eight or ten years of the early part of my profes- sional life, I was pretty actively engaged in practice, and I suppose treated, at least, my proportion of such cases. I regret that I must say that I have nothing to offer as a remedy nor any treatment to propose which promises much towards the cure of the disease ; for I have never seen a well-marked acute case get well. A very large proportion of the cases which I have met with, have been among negroes. In 1845 or '46, I lost three little negroes, on my plantation in Mississippi, with the disease. The children were at the Quarter, and under the exclusive management of careless negroes, nearly a mile from the dwelling house. I have always been of the opinion that the disease had its origin in the unhealthy condition, or unnatural cicatri- zation of the umbilicus; and in most of the cases with which I have met I thought I could trace the result back to bad management of the cord. In one case of the little negroes which I lost, there were evident signs of inflam- mation of the umbilicus. I have no recollection of having noticed any symptoms 29 which indicated cerebral disease in any case that I have treated. The cases which I have seen occurred invariably from the fifth to the tenth day after the falling off of the cord." The following communications from Dr. J. W. Morton, give additional confirmation of these views : " In answer to your interrogatories on the subject of Trismus Nascentium, I will say, that I commenced the practice of medicine in Williamson county, Ten- nessee, in a section of country very densely populated with negroes. The farmers owning these negroes, had on almost every one of their farms a number of breeding women, all of whom, when confined, were entrusted to female midwives, of the most ignorant order of women, some of them were the old women belonging to the plantation. With such services as could be rendered by these attendants, we could but expect that both mother and child would frequently suffer from neglect, if not from maltreatment, at their hands. This was by no means unfrequently the case. Trismus Nascentium upon some plantations occurred so frequently as to lead the farmers to conclude it was pecu- liarly and particularly confined to the offspring of some of their women, for they would loose a number of children in succession, leading their owners to suspect that the cause of the misfortune depended upon some malicious or bad conduct on the part of the mother. Indeed I have known masters who were ignorant of the cause of this malady, to become much exasperated with favorite servants, 30 believing they in some way maliciously caused the death of their children, and then sell them to traders with an express injunction they should be carried to the South. This the farmers would do as a punishment to the unfor- tunate mother, as well as to make an example of her to her fellow-servants, to terrify them from a crime of which they thought them guilty. Having located in such a region of country, it was my province to be very frequently called to cases of Trismus Nascentium. When I would arrive and enquire of the midwife or nurse what seemed to be the matter with the child, their almost universal reply was, the child had the bold hives, and they could not get them to break out Upon examination, I would find the child far advanced into Trismus Nascentium. In the early part of my pro- fessional career I read almost every authority of which I could get possession to inform myself as to the true cause of this malady ; but in vain. The authors seem to lead their readers to no just conclusion whatever as to what might be its proper source. Sometimes I was ready to conclude the disease depended upon some irritating cause in the abdominal viscera. Again I would conclude it v depended upon irritation of the spinal column, con- nected with irritation of the great sympathetic plexus of nerves. At other times upon some organic disease dis- turbing the brain or its enveloping membranes. Some- times I looked to the umbilicus as being the source of the evil. With all these conclusions before me, I was frequently left in very great doubt as to which of these causes I 31 should attribute the attack, and sometimes, I must admit, I was at very great loss to know whether or not I should lay the cause at the door of any one of them, or to all of them combined. But about fourteen or fifteen years ago, the precise time I do not now recollect, not having the Journal before me, in looking over the original communications published in the American Journal of the Medical Sciences, I saw and read the essay of Dr. Sims, then of Alabama, but now of the city of New York, with a great deal of anxiety as well as interest, upon the sub- ject of Trismus Nascentium. After perusing his essay, I thought he had discovered the cause as well as the treat- ment which would never fail to relieve it, Hence, I made known the discovery of Dr. Sims to my friends and patrons, assuring them I believed by his indefatigable in- dustry and observation he had given to the profession a key that would never fail to unlock the jaws of all tris- matic infants. Very soon I was called to a case. I examined carefully the child's head, expecting to find without the least trouble the displacement of the occiput, so graphically described by Dr. Sims; but, to my utter astonishment, the bones seemed to be in their proper position ; yet having so much* confidence in his theory as well as practice, I adopted his treatment of lateral position of the child, for several hours, at the same time using such other means as the case seemed to indicate, without the least beneficial effect what- ever. The result of. this case did not, by any means, de- stroy my confidence in the theory or practice proposed by Dr. Sims; for I continued to try the lateral position 32 every ease I saw before getting one in whidh I im- agined the occiput had been pressed forward beneath the edges of the parietal bones, all of which terminated in death, as the first had done. At last, I was called to a case, the child of a mother who had lost her two children born pre- viously to tins one. This mother expressed great solici- tude for the relief of her child, and upon my examining the child's head, and finding, as 1 thought, the displacement of the occiput, I immediately communicated to her, as 1 fancied, the cause of the distress of her child, and the opinion that I would be able to relieve it. I determined I would adopt Dr. Sims's treatment, first by dislodging the misplaced bone from beneath the parietal bones, secondly by enforcing strictly the lateral position prescribed by him. Having no instrument better suited to the operation, I used a common shoemakers's awl, pressing the point of the instrument sufficiently deep into the external table of the occiput to prevent its breaking outs, when I made very firm pressure backwards, until I con- ceived I had completely restored the bone to its natural position; to my astonishment, when I removed the awl, the bone resumed the position in which I found it. I made this experiment several times upon one side at a time, and then upon both sides simultaneously, with the same result. This child died in a short time after I ceased my experimental operations. Soon after this, I was called to a second case in which I imagined the occiput was pressed forward beneath the parietal bones ; upon this I operated also, with the same result as the other. 33 I now came to the conclusion, that either Dr. Sims was mistaken both in his theory and practice in Trismus Nascentium, or that I was wanting in dexterity to adopt his lateral position properly, or perform his operation with success. The result of these experi- ments left me in the same doubtful and unsettled opinion about the cause and cure of this malady. In fact, I very soon came to the conclusion, that there was no successful mode of treating it, and frequently when sent for to see a child laboring under the disease, I refused to visit it, acknowledging to those inter- ested I could do nothing that promised any relief whatever, not even as a paliative. For some years I gave up all such cases to their fate, and even now, I have no curative remedy to suggest, and when requested to visit a child with Trismus, I frankly tell the mes- senger that I can do as much for the relief of the little sufferer as any other physician probably could, yet acknowledge I can do nothing that would be of any material service. My experience is, that all such patients die as certainly as adults die of traumatic tetanus, of which disease a physician may probably see one case of recovery in the course of a long professional life. We must not think of curing the disease, but as you have very justly taught in your essay published some eight or ten years ago on the subject of Trismus Nas- centium, the safety of the child will depend -on the adoption of such hygiene measures as will prevent it. Your theory of the cause of this disease, and the ardent 3 34 manner in which yon have impressed it upon the students of the medical classes, to whom you have had the pleasure of lecturing since your connection with the '•University of Nashville as well as upon the profession , generally, through your essay, has saved the lives of more children, which might have died of Trismus, since its publi- cation, than all the remedies that have been employed for its cure since the days of Hippocrates. The condition of the umbilicus, it is true, is only an exciting cause of Trismus Nascentium, just as the prick- ing the sole of the foot of an adult with a nail is the cause of traumatic tetanus. There are various other causes acting upon the economy in either disease tend- ing to bring about a tetanic diathesis of the system, which only requires a very small exciting cause to develope the disease. There is scarcely a man in this com- munity who has not seen Tetanus in the adult pro- duced by pricking the sole of the foot with some sharp pointed instrument. Morgagni tells of a young lady who was attacked with the disease in consequence of a bite from a tame sparrow. Dr. Reid relates a case which occurred from the stroke under the eye with the lash of a whip, which was so light as not to destroy the continuity of the skin. Andral relates a case that was the conse- quence of a seton being inserted into the breast of a patient. The extraction of a tooth has been followed by tetanus. I have myself seen tetanus follow wounds so slight as not to excite the least attention whatever until the patient was completely overwhelmed with tetanic spasms. When we see this disease so frequently follow 35 wounds of so slight a character in the adult, how can we reasonably doubt that the cause of Trismus Nascentium is the irritation, inflammation, suppuration or ulcera- tion of the umbilicus. I am conscious of one fact, that since my attention has been directed to proper dressing and care of the umbilicus in the children of my practice, the mortality from Trismus has been reduced to at least one hundred per cent., even when the care of them has been entrusted to nurses." Dr* McCulloeh's cases are in full agreement with the general history of Trismus Nascentium.. The truths ad- duced by him accord not only with my own observations, but with those of others. Dr. Hansom's notes, taken while he was in Texas, show the great activity of predisposing causes; also, how gener- ally and easily children are affected by a morbid state of the navel, when they come under the influence of such predisponents. Dr. Clarke's hospital cases illustrate the same truths. After all, it is not very surprising that such predisposing causes should have been mistaken by Dr. Clark, and others, for the exciting cause. So little attention has been paid to the proper relation of causes by writers on this disease, that it seems very few have attached sufficient importance to remote influences, or to a particular diathesis of the system, but have been con- tent to examine alone into the exciting cause ; and this, consequently, when very weak or obscure, has not received that consideration which it even then deserves, in its rela- tion to a predisposition to tetanus. Hence the great 36 necessity of regarding these causes according to their mutual dependence on each other, that we may see their joint agencies, in producing an attack -of this disease ; also, that they may reflect a reciprocal light on the obscure plastic forces of the invading pathos. The gene- ral history of traumatic tetanus teaches us that it is more easily excited in adults by wounds sometimes than at others, according to the prevalence and activity of predis- posing causes. This all admit. Whence then the neces- sity or propriety of entertaining or propagating different opinions as to these causes, and their effects in cases of infantile tetanus,- associated as it often is with palpable irritation and inflammation of the umbilicus? Just here, I must reply to two very specious objections to a proper view of this subject. 1. That the navel may be badly inflamed, and yet not cause tetanus. - . • 2. That cases of Trismus have occurred wjien there was no inflammation of the umbilicus. But for these considerations many would doubtless have entertained a much greater dread of a morbid state of the umbilicus, and would oftener have employed tetano-pro- phylactic measures in such cases. Indeed, with no little astonishment have I heard well informed physicians say, they did not believe that inflammation of the navel is the exciting cause of Trismus, merely because they had seen very badly inflamed ones, without the occurrence of lock- jaw; or, that they had seen cases where the umbilicus had healed over. Verily my surprise would be only equaled by the assertion, that they did not believe that a 37 wound was the exciting cause of tetanus in the adult, because they had seen very bad ones fail to produce it, or had seen cases occur after the healing over of wounds. Almost every practitioner knows, from personal obser- vation that an adult may receive a deep, dangerous, and painful wound without incurring lock-jaw as a conse- quence ; also, that, a wound may cause the disease after having healed over. Then, may not severe inflamma- tion, or extensive ulceration of a child's navel run its course without causing trismus? and may not the part heal over and yet, by an occult pathological condition, excite the disease? When we are called to see an adult patient laboring under this malady, and learn that he has been suffering from a wound, however great or small, whether from a cannon ball or prick of a needle, we give ourselves no further concern about finding out the exciting cause; or, if we visit one in whom a recent wound has healed over, and who notwithstanding is suffering from an attack of this disease, we feel confident that the cicatrix is in a morbid state and has excited the disease. But when some practitioners are called to see an infant afflicted with teta- nus, they may learn that the child's navel is even badly inflamed, swollen and irritable, and yet ascribe the child's attack to some other exciting cause ! Or, an infant may be seen with the disease, when the umbilicus has healed over, and instead of referring the attack to an unhealthy irritable condition of the navel, though healed, as they do in cases of adults, this occult pathological state of the part is overlooked by them, and the disease is said to 38 have been brought on by some other exciting cause ! And yet, forsooth, had the little patient been an adult, with a badly inflamed, swollen, and painful umbilicus, or . with one that had just healed over, after having been in a morbid condition, the exciting cause would have been readily enough admitted. Hence, if I have not gained the point which I had in view, the Redudio ad absurdum, I have, at least, that of the Redudio ad discrepantiam. A strange inconsistency has indeed been presented. It is even preposterous, I must insist for any one to admit, that a slight wound, either before or after it has healed over, may produce tetanus in adults, and then deny that inflammation and ulceration of the navel do not excite it in infants, neither before nor after the part has healed. Really, when we reflect on the great constitutional deli- cacy of infants, their great proneness to cerebral, spinal, and nervous disorders, as well as their general suscepti- bility of disease, we would err less in supposing that their frequent sore navels were more likely to cause tetanus ia them, than common wounds in adults. Assuredly, both adults and infants are liable to attacks of tetanus after wounds or ulcers have healed over ; all admit that the former are, and that the latter are equally so cannot be either truthfully or consistently denied. A tetano-patho- logical condition of such cicatrices cannot be detected by any known means anterior to an open attack, especially in the cases of children, as they cannot complain of any irritation or pain which may be produced. And yet, we very often hear those of " fixed ideas" about their imagi- nary causes of this malady say, that in their cases the 39 navel was healed over and looked very well, consequently the disease must have been excited by some other cause than by a morbid state of that part. The fallacy of such a conclusion has been, I hope, fully exposed ; in further proof of which, however, many cases might be adduced, but I will only cite two, both of very recent occurrence : A few days ago I was called to see a negro boy ten or twelve years old suffering from a plain, fatal attack of tetanus, brought on by a small wound which had lately healed over and had been lost sight of until that time. I saw a similar case afterwards, with several physicians, equally as well marked and fatal in its termi- nation. I shall presently treat of its symptoms or varieties. My chief aim now is to recommend a reliable prophylaxis, by which, a' disease that cannot be cured, may be prevented. Just here, it might not be amiss to state, that occasionally a patient gets well of this malady; such a recovery is, however, only an exception to a general rule, which the attending physician sometimes mistaking for the general rule itself, has thereby been encouraged to treat a succeed- ing case with the same remedies which were supposed to have cured the case before, when to his surprise and mor- tification he found them of no avail. Many well-informed practitioners have lost all confidence in the common routine treatment of the day ; they entertain no reasona- ble expectation of relief, only as hope may be predicated on the recovery of a few exceptionable cases, independent of therapeutic agents. Hence, the great need of some prophylaxis. 40 The mother from whose fond embrace the infant has been suddenly removed by this unrelenting foe, at a time when she needed all the joy and comfort which her child could inspire, may well, ask, what is that, prophylaxis? So may the benevolent physician, who has been so often foiled and mortified in his best efforts to cure the malady ; even our farmers may well ask the question also in behalf of their slave interest. I will now state by w r ay of introduction to the prophy- laxis which I shall, with great confidence, recommend, that I have seen probably as much obstetric practice, both among whites and blacks, as any practitioner out of the large cities, and never has an infant been attacked with tetanus to my knowledge, of whose umbilicus I had the management. Prophylaxis. — Means derive far greater consequence from their salutary effects in particular instances, than we could otherwise attach to them. While we almost despise the enema commune, yet we glory in its effects, when by it, a dangerous and alarming obstruction of the bowels has been relieved. How lightly do we also regard the mere titillation of the throat with a feather until by its employ- ment we cause the stomach to expel from its depths a poison which in a few minutes would have destroyed the patient. Then we respect the means and rejoice in the effects. The lancet cut is but a small thing in itself, and yet we exult greatly in its triumphs over some of our most acute diseases. Then it is to the effects of the pro- phylactic measures, that I will direct the attention of the reader as well as the means themselves. 41 Physicians have generally given up the dressing and management of the funis too much into the hands of unskilful nurses, lest by a careful attention to such small things, they might compromise their fancied dignity. But every one who is properly impressed with a dread of tetanus from bad management of this part, will rather try to maintain his professional character and dignity by pre- venting a disease which he knows he cannot cure, however trifling the means may seem in the estimation of the ignorant, inexperienced or prejudiced. The umbilical cord should be divided as usual about two inches from the abdomen, and well tied with a suita- ble ligature before its division. After the child has been washed by the ■ nurse, another ligature should be applied lest the first one should become too slack from the con- traction of the cord. A hole of a proper size should then be made through a piece of soft old domestic or linen, four inches wide and six long, through which the funis should be passed, and afterwards carefully wrapped with another soft piece of cloth, two inches wide and three or four long. The cord should then be turned up towards the child's breast, and the cloth which was first applied should then be folded in on it from above and below, and from side to side. A soft flannel bandage should then be carefully put around the addomen and pinned with moderate tightness. After this should the navel-dressings become wet with urine or soiled with feces, they should be carefully removed and dry ones employed. This should always be done by an experienced and careful nurse, lest the cord be prematurely detached. 42 The chief advantage of wrapping the cord, is that of preventing it from adhering to the cloth through which it passes, and thereby preventing its removal when necessa- ry. All awkward, rough handling of the cord should be avoided as the navel string may be, in that way, stretched, torn, or prematurely detached. Our preventives begin in little things ; too little, I fear, to insure the regard which they merit; were they greater in professional esti- mation, they would be more commonly employed. As the danger of an attack of Trismus usually passes away about the tenth or twelfth day of infantile life — cases rarely occurring after that time — it will be the duty of the conscientious physician — no other will — to watch the umbilicus carefully and cautiously up to that period. This duty is not a difficult one, but may be performed with but little inconvenience on the part of the practi- tioner. But unfortunately this duty involves some little particulars, to which he can scarcely stoop. But he must stoop, if not "to conquer," to prevent, knowing that if he does not prevent, he cannot conquer. The prevention of an incurable disease, let it require whatever minor duties it may, should dignify and exalt them in professional estimation, and make it honorable to employ them. The umbilical cord, even during delivery, should be carefully managed in reference to this disease. It should be protected against too great an extension at the time of birth : by unwrapping it from around the child's neck, should it be around that part ; by not re- moving the child too far from the mother before it is divided. Any violent extension of the funis, in any way, 43 may pre-dispose it to separate by suppuration, ulceration, or sloughing. Besides, it might interfere with a healthful contraction of the ventral opening, and that of the vessels passing out through it. A proper contraction of these parts after birth is a part of the wonderful physiology performed by them ; for without, it, the cord cannot sepa- rate in a healthy manner, the abdominal opening cannot be closed nor the vessels which pass out through it. Hemorrhage, hernia, and other evils may ensue as con- sequences thereof. The parts which should contract after birth are: 1. The foramen ovale. 2. The ductus arteriosus. 3. The ductus venosus. 4. The umbilical arteries and vein. 5. The ventral ' opening. Should not a physiological con- traction of these foetal parts — now superceded by a change of the circulation of the "blood in extra uterine life— occur, the separation of the cord may be attended with danger: If the foramen ovale should remain too open, asphyxia and death may occur; or if only partially so, carbon may, for the want of free pulmonary circulation, accumu- late in the child's system, and produce debility and con- vulsions. And as the general health thus impaired, and the local congestion of the umbilical parts from partial returns of the foetal circulation, will not admit of a healthy desiccation and separation of the funis, Trismus as a con- sequence may follow. If the umbilical arteries were not to contract, the dis- turbances just mentioned might fill them with blood, and hemorrhage at the navel would then take place in all probability ; and if restrained their turgid condition would 44 not admit of a proper contraction of the umbilical opening, nor of a safe disengagement of the cord. Were the umbilical vein to remain patulous, the blood might regur- gitate through it, and bleed, if not prevented, at • the navel, especially if there were any obstruction of the as- cending cava near the heart. Were the ductus arteriosus to remain pervious, too much blood might pass out of ,the way of the pulmonary circulation. ; and in that way con- tribute its moiety of distress. An open state of the navel itself will, of course, greatly predispose to hernia, a gene- ral derangement of its anatomical parts, congestion of the vessels, hemorrhage, and sloughing of the cord. It may be said that there is nothing in all this likely to predispose -to Trismus by those who are not aware of the danger of a sore, navel. Hence, every thing calculated in the least to hinder the funis from coming away in a healthful manner may predispose to a dis- eased action of the umbilical parts. And as this part of my subject relates so directly to the anatomy of the umbilicus, I will give a short description of these parts, which are so strikingly illustrated in the annexed plate, the representation of a dissection, made at my request, by my accomplished and talented young friend, Thomas B. Buchanan, M. D. The ,anatomy of the umbilicus consists of almost every kind of tissue : Dermoid, superficial and deep-seated fascia and aponeurosis, muscular fibre, tendon, nerves and cord, with its vessels, covering and gelatine. As the abdominal muscles are well supplied with nerves from "the lower intercostal, ilio-hypogastrrc, and ilio- 45 inguinal nerves," the umbilicus of course participates in the endowment. ' The integument, after the detachment of the cord be- comes wrinkled and is folded in, and presents in front a cicatrix— a cicatrix from a physiological wound ! — in the strictest sense of the term. This cicatrix extends, of couise, through the entire ring — a cicatrix of several tis- sues, as we have just seen. Hence, we may expect often to find it in a diseased condition, which may give rise to tetanus, as well as an open ulcer.* Just under this integu- ment is the superficial fascia and aponeurosis, so finely displayed in Dr. Buchanan's dissection, as seen in the plate. Next may be seen the aponeurosis of the internal oblique and transversalis. Hence, the umbilical ring is formed in part by the marginal contribution of the linea alba, which is itself formed by the " blending of the ante- rior aponeurosis of the oblique and transversales nluscles." The transversalis fascia is also finely displayed. The umbilical cord with its vessels are represented very promi- nently; the two arteries may be seen, as they emerge from the navel, entwined around the vein. *Thc writer once attended a well marked case of traumatic tetanus, caused, doubtless, by a physiological lesion in another part. The uterine surface from which the placenta had been detached, like any common wound, passed into amorbid condition, and produced the disease about a week after delivery. Dr. B. W. A vent, a very intelligent and well known' Physician and Surgeon, -also, saw this case and concurred fully in the views just stated, both as to the cause and diagnosis. .The prognosis was of course unfavor- able, and was verified in a, few days. The physiology of procreation produces more lesions than any other variety thereof, so closely resembling ordinary wounds, that we would re- gard them as such were they to occur in ordinary ways. Thus we have periodical hemorage,, lesions of the Graafian vesicles, severance of the pla- centa from the internal surface cf the* uterus, and on the part of the infant a separation of the cord from its abdomen. Two of these lesions may take on a morbid state and then cause. a traumatic tetanus. 46 1. The integument everted. . 2. 2. 2. Superficial fascia and aponeurosis of external oblique. * 3. Recti muscles. 4. 4. Aponeurosis of internal oblique and transversalis. 5. Transversalis fascia. 7. Umbilical cord dissected. 8. Vein. 9. 9. Arteries. * •^ ** -**-"' ^Mi^r# .*•**«•-«•«»#.» 49 Thus we see that the umbilicus is formed of a variety of tissue, through which a physiological lesion must of course exist, and which must be closed by a cicatrix of the same kind, resembling traumatic lesion and healing so closely that we might almost predicate tetanus on its physiology, independent of its pathological changes. At least no one can deny the necessity of guarding this teta- nic point, for, eight or ten days after birth. A diseased, irritable state of, these parts is well calculated to give rise to tetanus, abounding as they do in nerves, fascia, aponeu- rosis, both superficial and deep-seated, dermoid, and mus- cular structures. They constitute a week point at the ventral opening, to say the least, where a natural state may pass more readily into an unhealthy one, than in any other part of the child's economy. Even a failure in their natural contractions as we have seen may produce many pathological results. The best remedy for this state of things is Ashwell's alum bath. About one-fourth of a pound of pulverized alum should be dissolved in a vessel of tepid water, large enough for immersing the child up to the neck, where it should be held and carefully supported for ten or fifteen minutes, two or three times a day, according to the nature of the case. A little spirit of camphor, some pure brandy or aqua ammonia may be added if the child be very feeble. This bath is clearly indicated when symptoms of asphyxia, attended with blue lips, livid countenance, defective respira- tion, and feeble pulse occur in early infancy, denoting a partial recurrence of the foetal circulation. And as all this may be referred to an open state of the parts just 50 mentioned, it will be highly necessary to promote their closure ; and I feel confident that" there is nothing better for immediate use than the bath just recommended. As the infant, while in this condition, may lose its ability to nurse at the breast, it should be fed by a spoon with warm maternal milk. A few drops of the aromatic spirit of ammonia, with sugar, well diluted and carefully administered may also do good. As soon as the child is taken out of the bath, the abdominal bandage and navel -clothes should be removed, and dry soft ones re- applied. The umbilical surface should also be anointed with simple cerate, to prevent ill effects from the alum and ammonia. As the crying of the child is very apt to disturb the navel, as well as its dressings, great care should be taken during the first eight or ten days to prevent hard spells of it. The abdominal bandage should be applied in anti- cipation of such paroxysms ; and the dressings should be examined daily. Should they become soiled with feces or urine, they must be removed, and clean, soft ones applied. All jolting or improper handling of the infant should be avoided, as much injury is often done in that way ; by it the cord may be ruptured or injuriously stretched. The umbilicus may suffer from an improper mode of dressing : nurses have a bad habit of clouting by pinning the cloth in a bulk over the navel, which will press directly on it, whenever the child cries, strains, kicks, or draws up its lower extremities. This error should be corrected. Spells of colic also have a bad effect on this part, and afford an .additional consideration for giving as prompt 51 relief as passible. Entire cleanliness must also be regarded as one of our prophylactics. It will sometimes, though not often, be necessary to employ local medication of the umbilicus before the funis is detached. Should the cord become dry and hard, without separating at the proper time, and the surrounding surface irritated by it, it will be necessary to raise the dressings and apply a little warm olive oil ; or remove a portion of it, if it be thoroughly dried, and the parts well contracted, with a sharp pair of scissors. No portion of the cord should be thus divided, except it be entirely dry, and its vessels impervious. Occasionally it will be necessary to divide a small remaining thread of the cord, especially if any local applications are necessary. But even this should be done circumspectly. On the contrary, should healthful desiccation not take place, or only partially, and the navel string remain soft and large, attended with ul- ceration and suppuration around its base, the dressings may be carefully removed and a soft astringent poultice applied, with the double motive of producing contraction of the ring and allaying irritation of the inflamed sur- face. A little corn meal cooked with a decoction of oak bark, will make the best poultice. The funis occasionally separates by sloughing, emitting a bad odor, and exhaling an irritating moisture. In such cases, the part should be well secured in a dry soft cloth, the surface under it washed with milk and water, and well oiled, to protect it against the irritating effects of tho exuding fluids. A little fungus may spring up just at the point where 52 the cord separates, this should be carefully touched with caustic a few times, according to results. — Always after the detachment of the part the surface around the navel should be washed with warm milk and water, then well dried, and a little simple cerate applied to the surface, and a good abdominal bandage put around as before ; the use of which should be continued for some time; more especially if there be any tendency to a pouting of the part. Lastly, after the funis has separated, the umbilicus should be carefully washed with castile soapsuds, and if there be the least appearance of irritation or inflamma- tion, a soft mush poultice, twice the size of a dollar and about twice as thick, throughout its whole extent — lest the edges become dry — should be neatly spread on a soft piece of cloth, then moistened on its surface with a little lead water and olive oil, or prepared as before with oak bark tea, and laid with care immediately over the navel, and should be retained in its place by a proper application of the bandage. This poultice should be removed in six or eight hours and another applied, and so on until all signs of a morbid state of the part entirely disappear. It will sometimes be necessary to continue this course of poulticing for five or six days, to the entire exclusion of all other topical applications, such as calomel, red precipitate, spirits of turpentine, &c, as their prophy- lactic powers are very inferior to those of the compound poultice just recommended. All predisposing, accessory or accidental causes of irritation should be guarded against with great care; the general health of the child should be 53 -closely watched, and internal remedies employed if neces- sary. Soft, emollient poultices, certainly afford even an adult, suffering from a wound, greater protectiou than any other means. Who «ver saw a patient attacked with traumatic tetanus, who had had all the prophylactic benefits of good poultices, a well regulated temperature of his room, and appropriate internal remedies? The soothing action of the poultice seems indeed to prevent a wound from passing into that condition which excites lock-jaw. The terminal extremities of the wounded nerves, or those that have been exposed by ulceration, or irritated by inflammation, are protected by a poultice against that tetano pathological condition into which they pass sometimes, when not thus guarded, with great facility. But alas! because the inflammation of the navel is trifling, or the ulcer on it small, the physician does not consider either worthy of his attention, when, really, the the very elements of death 'are more actively at work than in many cases which so readily engage his closest attention and greatest skill. It is probable that a greater amount of human life might be saved by these simple preventives, than most physicians or nurses are aware of; and it is always far more difficult to procure the employ- ment of such prophylactics, than those uncertain remedies which are so zealously administered sometimes for the relief of an incurable malady. Nurses should be properly directed to employ these means, especially among our negroes ; and every practi- tioner should constantly urge their adoption in negro 54 quarters. When these means are faithfully employed, negro children escape tetanus to as great an extent as do white children. It should be the resolve of every practitioner never to allow an infant to be attacked with trismus that may be delivered by him, or placed under his care at birth, since by a patient and careful employment of appropriate prophylactics it may be prevented. These means, simple and unpretending as they are, require some oversight and tact for their benefi- cial employment : if the poultice be not well applied, of improper consistence, or become dry and hard, it may do more harm than good. Besides, if the child be not pro- tected against wet and soiled clothing, bad air, variable temperature of its room, a bad habit of body, bad feeding and nursing, these predisposing, accessory and accidental causes, may determine the morbid umbilicus to pass into a traumato-tetanic condition in despite of poultices or any other topical applications whatever ; so it is highly neces- sary that all these things — little in themselves though great in their effects — should be scrupulously regarded by every practitioner. The writer of this treatise, while faithfully discharging his duty to infants in the employment of these prophy- lactic measures, has often experienced the jeers and taunts of nurses on such occasions. Every practitioner should, however, perform his duty to his little patient, be it white or black, in protecting it against an attack of a disease which he may prevent but cannot cure, and there- by impress nurses, parents, and even communities with the great utility of such a course. In that way our pro- 55 phylactics may be raised above the contempt of ignorant crones or those too wise to learn. Admitting, as we are compelled to do, that we can but seldom treat this disease successfully, yet it will be pro- per to give a full detail of its symptoms, diagnosis/prog- nosis, pathology and treatment. Symptoms. — These at first are vevy obscure, and may be overlooked both by the physician and nurse. It is so very common for infants to cry, and thereby manifest only slight ailments that the early symptoms are usual- ly referred to some ordinary indisposition which does not excite much concern. During the first week the child has probably been quite healthy; has nursed well, slept well, and has done so well in every respect, that scarcely any apprehension is entertained about its safety, until on the eighth or ninth day, when the child's cry is modified, and evinces dis- tress ; it also whimpers and does not rest so well. These premonitory symptoms will soon be followed by a quickened pulse, distress of countenance. These will be associated with other symptoms about this time, such as rigidity of the muscles about the neck and face, a disinclination on the part of the child to nurse, while the endeavors of the anxious mother to get it to do so may be unavailing. The child will either push the nip- ple out with its tongue, or in the attempt to nurse, should it draw any milk into its mouth, will strangle and sometimes very badly. The alarmed mother will try again and again to get her child to nurse, supposing that it has the colic, hives or something of the kind. She 56 will then probably try to get her babe to swallow some domestic remedies, and failing in that also, the family physician will be sent for; on his arrival he will find the child's countenance greatly changed; the skin on the forefiSd will be wrinkled, the eyebrows knit, the skin on the cheek drawn upwards and backwards, also the angles of the mouth, thereby thinning and compressing the lips against the gums. The eyes will be partially closed, and will roll upwards or become fixed in their sockets. The contour of the mouth will be changed, sometimes remaining slightly open in an elliptical form. The under jaw is fixed and cannot be separated from ;he upper one, presenting now the unequivocal symptom )f Trismus. The patho-physiognomy of the disease is now fully established. There will now be great rigidity of the muscles of the neck, spine, abdomen and extremities. The abdomen will feel hard, the extremities will be more or less stiff, and the back will be curved either backwards — episthotonos — or forwards — emprosthotonos — and in some rare instances laterally — pleurosthotonos. The lateral tetanic flexure is the most unusual, the procurva- tion the most favorable, and the recurvation the most fatal. If the umbilicus be examined it will in all pro- bability be found in a pathological state of some kind, most commonly inflamed and irritable. As the disease advances the flexure of the spine backwards — the most common variety — along with the reversion of the head increases. The tonic spasms become greater and faster; they will occur every twenty, thirty or forty minutes, without complete relaxation of the muscles during their 57 intervals. All ability to swallow is occasionally lost, the jaws become immovably fixed, and in the course of twelve, twenty-four, or forty-eight hours the infant will be destroyed by a hard spasm or die comatose. Sometimes, however, infants live eight or ten days, the disease then becomes chronic, and they may recover. There is seldom much or any febrile excitement, but on the contrary often coldness of the surface and extremities. The pulse is generally quickened, and the bowels torpid. The brain is not much disturbed until towards the close of the malady. The symptom of Trismus may be com- plete, partial or not exist at all. In the latter instance the child may continue to nurse and swallow through the whole course of the disease. The writer once attended a fatal case of this kind, which, a learned professor, who incidentally saw the case while under treatment, attempt- ed to relieve by the use of chloroform, but failed most signally. Hence, I infer that the absence of trismus, in this dread- ful complaint does not lessen the danger, though the disease presents a much more favorable appearance; for when seen in its trismatic features, of unyielding spasm and intense suffering, the appearances are horribly dis- tressing, and cannot be easily forgotten. I have procured a very excellent likeness of this infan- tile patho-physiognomy. By the professional courtesy of Dr. Conwell of our city, I ob f ained leave of one of his families to have a drawing taken of a fully developed case, by a very adroit lithographist, Mr. Wagner. It 58 may be seen and examined on the annexed plate. In this case, the umbilicus was badly inflamed, swollen, and presented a very irritable appearance. The disease came on about the sixth or seventh day. No remedies did any good, and the child died in forty-eight hours from the attack. The extremities were more affected than usual, and the spine though recurvated considerably, yet the flexure was not as great as sometimes occurs, nor was the head drawn backwards as far as I have seen it in other cases. But it was a very plain, rapid arid fatal case of infantile traumatic tetanus. I should further state that in this case the cord sloughed, which is the worst manner in which it can separate. Diagnosis. — This disease has been confounded by most writers with clonic spasms or convulsions ! Even Condie, a systematic writer on the diseases of children, has done so. If we may judge from Jtiis few remarks we may infer that he cared but little about it. Other good writers are equally culpable. Evanson and Maunsell of Ireland, evade responsibility about it by stating that, " It may justly be considered as an hospital disease." Whether the children of Ireland ever suffer from it out of their hos- pitals or not, I am not now prepared to answer; but I know very well that infants of Irish parents frequently do in our country ; hence I infer that it is most reprehensively overlooked among the poor of that coun- try. Even the practical Dewees says he can see nothing positively dangerous in a diseased navel ! And West, a copi- ous writer on other infantile disorders, writes impatiently and confusedly about this. He even questions the pa- thological signs which he has stated in regard to it. 1 Mr* 59 This much neglected pathos is by no means without its diagnostic symptoms ; signs by which it may be con- tradistinguished from all other infantile convulsions. These are so characteristic of the complaint that it is very astonishing it should ever have been confounded with other nervous disorders. They are as plainly differ- ent from those attending such affections, as are Epileptic convulsions from tetanic spasms in the adult. And there is no more reason for confounding infantile tetanus with ordinary clonic spasms, than that of adults with epilepsy. There is about the same variety of tetanic cases among the former as is among the latter; and each variety is of course attended with a corresponding modification of symptoms. These may in both instan- ces be sometimes very mild and obscure, and in others very active and plain. The symptom of Trismus — rarely ever absent — aids us more than any other in forming a correct diagnosis. But even in its absence the rigidity of the muscles of the neck, distortion of the spine, and the tonic unrelenting spasm, would determine the true nature of the case. Besides, tetanic spasms are unlike all other varieties for they never intermit completely, but continue in degree all the while; nor do patients lose all con- sciousness during their continuance, as they do generally in convulsions. When all these symptoms are present, such as trismus, reversion of the head, incurvation of the spine, tonic spasm of the voluntary muscles, inability to swallow without strangling, with an inflamed umbilicus, how, I 60 ask, could we have a plainer case of traumatic tetanus, taking into consideration the fact that these charac- teristic symptoms came on about the same time in which they would in the person of an adult after the reception of a wound. Were they to occur in an adult case about the same time after a wound the merest tyro in medicine could hardly fail in diagnosing the disease. Why then should good observers admit that the disease has its source in the one case evidently in a wound, and not in the other? On one occasion I was requested to examine an infant with all the plain diagnostic symptoms of traumatic tetanus, by an old, experienced and respectable physician who had the case in hand, and to my great astonishment, he had entirely overlooked the true nature thereof, and but for maternal solicitude would have given the case but little consideration. He said that I was over- anxious about the child, that it would be well in a few days, but in this he was mistaken, for it died in a short time. This infant had a badly inflamed navel, of which he was ignorant until I directed his attention to it. The symp- toms of traumatic tetanus were plain, but because they occurred in an infant they were disregarded by this prac- titioner, and had I not seen the child the disease would have passed for something else. Thus we see how this fatal malady is doubtless often regarded. The observing physician who understands the diag- nostic signs of this disease, will have but little difficulty in making out an acute case, but in its chronic form there may be some difficulty, especially if the child be recov- 61 ering and the symptoms mild. The previous history of the case must be patiently enquired into, and the symptoms just enumerated, however mild, have diag- nostic characteristics. Most of these signs are pathog- nomonic, and generally there are but few adjunctive ones to mislead. Probably there is no infantile dis- order more, clearly pronounced by its symptoms than this one, and yet none has been more overlooked, mistaken and maltreated! Prognosis. — This, if our diagnosis be correct, should of course be unfavorable. A few cases become chronic and recover, but not a sufficient number to justify a favor- able, or even an equivocal opinion. An unfavorable prognosis might, however, be followed by the statement that a few recover. This will temper the harsh declar- ation a little; but we should be particularly cautious not to raise hopes which in all probability may not be realized. The physician's opinion should be cautiously communicated to the mother, lest the shock of an unfa- vorable one injure her. Her puerperal state will re- quire this. It will suffice at first to let her know that her child is ill, and a short time afterwards that it is dangerously so, and at a proper time that it may die very soon. A little maternal hope will soften and qual- ify all these painful statements, and greatly lessen their injurious effects. Let her hope be gradually extin- guished, not too suddenly," for we should not forget that we may be dealing with two lives ! Besides, the physi- cian should be very certain of the correctness of his diagnosis, before he expresses so grave an opinion. How 62 could a mother excuse a mistake which might torture her unnecessarily for several days and nights? Pathology. — We know of scarcely any pathological lesions beyond the umbilicus. Post mortem examin- ations have revealed but few if any. Although the chief seat of the disease be in the spinal cord and spinal nerves, yet they do not manifest any appreciable patho- logical changes after death, significant thereof, according to our most accurate observers. West, in his work on the diseases of children, states that he found in his ex- aminations of three cases after death, there was an effusion of blood in the cellular tissue surrounding the theca of the cord, and a congested state of the vessels of the spinal arachnoid, and sometimes an effusion of blood or serum into its cavity. But in consequence of finding similar appearances in the bodies of infants which had died of other affections, he hesitates to accept those just mentioned as true pathological lesions of Trismus Nas- centium. It seems very reasonable to suppose that the pharanx and esophagus, will be found after death con- tracted and inflamed. Doubtless in bad cases, the chief pa- thological signs after death, will be found in the spinal cord,, teaching us the importance of addressing active remedies du- ring life to that part. As this morbus pervades the whole spinal cord, our remedies, for its relief, must be prompt, active and well directed, probably more so than has gen- erally been done. Treatment. — The management of cases of this kind would be a better term than the treatment of them in a medical sense. Treatment will be required, and we must 63 manage them in the best manner. Although we may have lost confidence in all remedies in consequence of their constant failures, yet we must continue to employ them ; for the particular case of which we may have the management may be an exceptional one, " and unlike others, may be amenable to our remedies. Prof. W. T. Briggs, my present co-partner, has just in- formed me that he lately treated a well marked case suc- cessfully. It came on about the usual time after birth, and was attended with a very bad state of the umbilicus. The cord sloughed partially at first, and left a portion in a half sphacelated condition, adhering to the navel, from which an irritating discharge constantly exuded, and kept up a great deal of irritation and inflammation of the umbilicus. But by means of a soft emollient poul- tice to the part and the internal use of two drops of laudanum every two or three hours he succeeded in relieving the little patient. The result of this and similar cases is encouraging, and teaches us that we should always try to cure the disease. I will, therefore, advise the following plan of treatment : — In the first place apply a soft emollient poultice to the child's navel, let its condi- tion be as it may. Give from one to two drops of lauda- num every two hours, watching its effects : but should the child not be able to swallow the medicine, employ it as an enema with a thin solution of starch — lour or five drops repeated in that way every three or four hours, and if this be voided too early, clothes saturated with it should be applied to the epigastrum, taking care that too much of the drug be not absorbed. If the child be 64 plethoric a leech or two should be applied to the spine, and immediately afterwards, its whole course from the occiput to the coccygis should be vesicated, either by the vinegar of cantharides or strong aqua ammonia. It is easy enough to prevail on mothers and nurses to give laudanum and similar drugs in this disease, but they may object to extensive vesication of the spine; hence it will often be necessary to explain and insist on this particular remedy. EfttUTi..— In note, page 45> for " heinorage,'* read hemorrhage, At page 1^ 14th line, fef " their, * read there. I3STDE-X Introductory i-xvi History 4 Dr. Sim's Theory 5 Strictures thereon 6 Predisposing Causes 11 The Exciting Cause 14 Separation of the Umbilical Cord 15 Remarks on Dr. Joseph Clark's views 17 Condition of Infant at Birth 18 Negro Children 20 Prevalence of the Disease at Particular places 22 Contribution from Dr. McCulloch 24 " " " Dr. Ransom 26 " . " " Dr. Black 28 " " " Dr. Morton 29 Inflammation of the Umbilicus 36 Trismus Nascentium. essentially the same as traumatic tetanus in the adult. 37 Prophylaxis 30 Division of the Umbilical chord 41 Mode of dressing the Umbilicus 41 The fetal parts which contract at birth 43 The Anatomy of the Umbilicus 44 Plate, with references 46 Physiological Lesions 45 Management of the Umbilicus 1 50 Poultices 52 Symptoms of the Disease 55 Diagnosis 58 Plate 2 58 Prognosis 61 Pathology 62 Treatment 62 *D058805