5530 A TREATISE ACUTE AND CHRONIC DISEASES NECK OF THE UTERUS. ILLUSTRATED WITH NUMEROUS PLATES. COLORED AND PLAIN. BY CHARLES D. MEIGS. M.D., PROFESSOR OF MIDWIFERY AND THE DISEASES OF WOMEN AND CHILDREN IN JEFFERSON MEDICAL COLLEGE; MEMBER OF THE AMERICAN MEDICAL ASSOCIATION; OF THE AMERICAN PHILOSOPHICAL SOCIETY, AND ONE OF THE COUNCIL; VICE-PRESIDENT OP THE PHILADELPHIA COLLEGE OF PHY- SICIANS; AUTHOR OF "OBSTETRICS, THE SCIENCE AND THE ART;" "WOMAN, HER DISEASES AND REMEDIES:" " A TREATISE ON CERTALS OS THE DISEASES OF YOUNG CHILDREN," ETC. ETC. PHILADELPHIA: BLANC II ABD AND LEA 1854. Entered according to the Act of Congress, in the year 1854, by BLANCIIARD AND LEA, in the Office of the Clerk of the District Court of the United States in and for the Eastern District of Pennsylvania. PHILADELPHIA: T. K. AND P. G. COLLINS, PRINTERS. rarj WP if 70 TO ROBERT M. HUSTON, M.D., PROFESSOR OF THERAPEUTICS AND THE MATERIA MEDICA IN JEFFERSON MEDICAL COLLEGE AT PHILADELPHIA. My dear sir : — You are aware, I believe, that by command of the American Medical Association, I was directed, as chair- man of a committee appointed at Charleston, South Carolina, to present a Report to that body on the subject of Acute and Chronic Diseases of the Cervix Uteri. Professor Channing, of Boston, and Dr. Thomas H. Yardley, of Philadelphia, who were of the committee, confided to me the duty of drawing up the Report, which was presented to the Association at the New York meeting in May, 1853. The paper, with the drawings, was ordered to be printed and engraved, and may be found in the last volume of the Transactions. Under the impression that the views of disease and suggestions of treatment in this paper might, if more generally diffused, prove of some service to our profes- sional brethren, I have, with the liberal consent and full approval of the publishing committee, made a sepa- rate volume of the Tract, which I beg you to allow me to dedicate, thus publicly, to you. I hope you will 6124024 IV DEDICATION. accept it as a mark of my most sincere respect and warm attachment. I pray you also, as far as you properly may, overlook its numerous faults of substance and form ; to receive my book with wonted kindness, and continue to favor me, as long as I live, with that course of kind and friendly conduct, which, together with my high appreciation of your sterling abilities and candor as a man, has long made me, and ever shall make me, feel that I ought to be, and am your sincere and re- spectful friend and most grateful servant, CHARLES D. MEIGS. 324 Walnut Street, Jan. 15, 1854. ON ACUTE AND CHRONIC DISEASES THE NECK OF THE UTERUS. The great prevalence of cases of sexual disorders has of late called much of the attention of physi- cians to a consideration of the causes, signs, and treat- ment of those affections, and several recent publications have thrown much light on them. It was to be expected that the labors of ingenious men, devoted to this species of research, should, by this time, have placed all questions in this kind of practice so fairly before us, and with solutions of the various problems so clearly exposed, that there could be no farther real necessity for making public one's observations or reflec- tions. It is, nevertheless, undeniable that our daily clinical experience, as well as what we notice of the current medical literature, and what we behold around us among the sick, all concur to prove that it is in general 2 18 ACUTE AND CHRONIC DISEASES esteemed to be a difficult thing to comprehend the va- rious disorders of the womb, and appreciate their pecu- liar reaction upon the constitutions of women. Notwithstanding the numerous learned works we possess, whether they be of ancient date or modern, it does appear to me that this class of disorders, as to the clinical duties at least that are connected with them, are not so well understood as they ought to be, and that this is the chief reason why so many of the cases tend, at last, to fall under the care of a few individuals, who may have acquired a sort of fame or notoriety for success in their treatment, instead of remaining, as they ought, in charge of the family physician or surgeon, usually the first to be consulted on account of them. I regard this tendency to specialization as a thing most injurious to the profession, which ought to be a whole in the whole and a whole in every part. Such specialization of the office of the physician is very far from tending to elevate the whole body in its usefulness to the public, however it may serve to exalt the inte- rests of a few individuals, and it must be confessed that any specialization as to this sort of clinical duties is both highly inconvenient to the people, and disparaging to the profession at large, while it is wholly uncalled for by the nature of the cases. A little consideration might serve to convince us that this class of disorders presents to the practising physician nothing more essen- tially inscrutable, or intractable, than the ordinary com- plaints submitted for examination and advice to the gentlemen of the Art. OF THE NECK OF THE UTERUS. 19 There would be less propensity to bring them into the class of a specialty in practice, if the treatises now in our possession, were as clear in the description and illustration of disease, and as precise in the indication and relation of methods, as they ought to be. Far from this — we have to regret that many of the drawings and colored prints serve rather to obscure, than enlighten the path of the practitioner. It needs only to glance, for example, at the plates to Madame Boivin's work, to see that this remark is quite just, while the more ele- gant volume of Dr. Hooper affords as little aid — his engravings, however beautiful, exhibiting for us only the ravages of diseases ended in death, and not those curable forms and stages, which are far more worthy of investigation, as guiding us in our attempts to cure. It has seemed to the Author, that, before entering upon the examination and description of the special cases, he is called upon for a few remarks concerning methods of proceeding — the usefulness and propriety of which have, by some, been sharply called in question, while others have contended that they are indispensable to correct diagnostication and treatment. I allude to the method introduced by M. Recamier, Physician to the Hotel Dieu, at Paris. That celebrated professor, in his work entitled Recherclies sur le Traite- ment clu Cancer, 2 vols. 8vo. Paris, 1829, says, at page 317, t. i. :— " Des l'annee 1801, consulte frequemment pour des maladies organiques de l'uterus, je coinmencai a traiter 20 ACUTE AND CHRONIC DISEASES les ulceres du vagin et du museau de tanche de la merae maniere que ceux de la gorge, qui m'en donne- rent l'idee. Un tub d'etain du volume du doigt, et de quatre ou cinq pouces de long, servait a ces panse- ments, dans lesquels les surfaces ulcerees etoient touchees avec un pinceau de charpie trempe dans du miel rosat, ou dans du rob de Daucus, seul ou associe avec du collyre de Lanfranc, du laudanum de Rousseau, ou de l'extrait d'opium." M. Recamier farther informs us, that, in 1812, M. Bayle inquired of him concerning his methods, and that the facts he communicated to that author were made public in the Diet, des Sci. Med., art. Cancer, which notice is found in torn. iii. p. 604, as follows : — " Deja M. Recamier est parvenu a porter differentes substances medicamenteuses immediatement sur l'ulcere, a l'aide d'un pinceau conduit dans un tube de gomme elastique ou de metal qui ecarte les parois du vagin, et embrasse dans son orifice superieure toute la partie saillante du col de i'uterus. Ces essais, conduits avec prudence, conduiront peutetre un jour a quelque methode de traitement, plus efficace que celles aux quelles nous sommes encore reduits." The great success, in treatment, that attended M. Recamier's practice at the Hotel Dieu and the city ge- nerally, led to the introduction of Ms method, which may be denominated the surgical method of curing the disorders of the cervix; and the question now is, whether the advantages resulting from it are sufficient to counterbalance certain evils supposed to have grown OF THE NECK OF THE UTERUS. 21 out of its introduction. These evils, it is alleged, consist in the great mortification which any sensible woman must experience, if subjected to a metroscopic examination — some laxity of the moral sense likely to grow out of such proceedings — the physical injury, by contusion or laceration, sometimes attending the opera- tion, and the mischievous effects of violent drugs and dangerous instruments, to the employment of which it leads and tempts us. Farther — it is asserted to be un- necessary, since the exploration by touching, as it is called, reveals sufficiently well the nature of diseases at- tacking the cervix uteri. I shall not here discuss the moral differences between a diagnosis made by the operation of touching, and a metroscopic one. Either of them is bad enough, in itself considered ; but as neither of them could be sup" posed possible, except out of some direful necessity of the patient, and as the one is not essentially more revolt- ing to the feelings of the sufferer than the other, it ap- pears to me that the argument is as valid against the one as the other. No one will deny that the delicacy of those relations that exist between medical people and their female patients, opposes, in a variety of cases, an insuperable barrier against any successful treatment whatever, for there are found individuals so fastidious as to prefer pain, disease, and even death itself, to any revelation concerning their disorders. Some women, who do not object to relate the history of their diseased sensations, compel us to rest satisfied with such barren histories as they themselves can give, 22 ACUTE AND CHRONIC DISEASES and medical men, it is presumed, are often obliged to adopt an empirical method, or — to use a common phrase — to guess at the seat, nature, and phasis of the disease, as well as the remedies for it, rather than resign the woman to hopeless distress on the one hand, or, on the other, urgently insist upon her waiver of that fastidious sentimentality which ought, to a certain extent, to rule her professional relations with the medical adviser, but not wholly and exclusively, and to her ruin. Even to examine by Touching, does, in many parts of the United States, appear to be a revolting proposition ; and there are some persons who prefer to make jour- neys of hundreds of miles, in order that such an inquiry, supposing it indispensable, may be instituted by a stran- ger, and far from home. Some examination is, never- theless, often an indispensable requisite to correct infor- mation as to the sanitary wants of the patient ; and physicians cannot always rely upon the historical relation of the patient herself or her friends, who assuredly can- not impart knowledge which they do not themselves possess, and can by no possible means acquire. It may be farther averred, that the Touch alone does not surely impart this knowledge ; for as much as a tint or color is often the clearest exponent of a morbid state, it becomes sometimes an imperious necessity to ascertain it by the metroscope. The question is, then, not whether the instrument informs us better, but whether, without its aid, we could at all learn our the- rapeutical or surgical duty to the subject. The objection as to danger of injury, and that other, OF THE NECK OF THE UTERUS. 23 the temptation to make use of too violent topical remedies, is a question of the good sense and prudence, or con- scientiousness of the medical man — subjects not for us to discuss. Yet, we may adventure the remark, that no sincere person will deny, that, in our profession in these United States, there exists a great majority of gentle- men, competently educated ; men skilled in their art ; men of probity, and having elevated views in morals and religion; and, as to life and conversation, irre- proachable. If the whole class of cases under consideration should be confided to such persons as these, little objection would be made to their professional opinions or practice. There is conceded to them, by common consent, as well as by governmental authority, a "jus docendi scribendi atque exercendi, ubi rite vocaii fuerint ;" and the public esteem them to be warranted in all their acts, done within the metes and bounds of their real professional privileges. They have no authority to violate those rules and arrogate privileges beyond; and when they do so it is at their own peril. The question, then, seems to be still more narrowed down; and we have only to determine what is, and what is not, strictly within the limits of our duty and preroga- tives — things to be resolved, not by formal council, but by the physician himself, upon the spur of the occasion. We must not repudiate, and, by wholesale reprobation, condemn and annul a good method of cure, merely be- cause incompetent or wicked persons might or do abuse it to their own gain : to do so, would be to amerce 24 ACUTE AND CHRONIC DISEASES and punish the sick and the miserable for faults of our brotherhood. Lastly. — Even if it be true that some abuses, disgrace- ful to Medicine, do exist, we are persuaded that such discreditable examples must be very rare among a class so generally acknowledged for wisdom, virtue, and po- liteness, as the great body of the United States physi- cians. Wherefore, we do not find ourselves called upon to discountenance and reprobate the prudent and neces- sary employment of modern methods and instruments, invented to improve the means both of diagnosis and surgical treatment of diseases of the cervix uteri; con- ceiving that this is a matter to be left to the conscience and judgment of our brethren, whenever the occasion may arise. The reactions of the reproductive organs upon the other members of the animal economy are known to be both diverse and comprehensive ; nor is it difficult to perceive that this should be the case, seeing the great importance of their functions. One could hardly sup- pose, indeed, that a system of anatomical tissues, repre- senting the complement of the vital powers, could be an indifferent in their constitutional reaction. The powerful sway they exert upon not only the physical, but the psychical condition and nature of the woman, might well persuade us that changes in their vital status, even such as are inappreciable except by the reason, should greatly affect both the body and mind of the woman. OF THE NECK OF THE UTERUS. 25 The reproductive force can never, in fact, be an indif- ferent, as regards the health and perfection of the woman — who is always an imperfect being until she has, at full puberty, acquired this complementary force, and begins to decline from her perfections as soon as she lays it down at the change of life. During all the period in which she possesses this force, even very slight modifica- tions of it must affect the direction, as well as intensity, of many others of her physiological actions. It is probable that the Hysteric malady, which assumes such diverse forms, and comprehends in its range, so many separate and distant organs, depends essentially upon a vital status of the reproductive viscera, often so slight as to escape all sensible detection. It is, at least, certain that sexual diseases do give rise to severe distress in distant regions of the body ; and, while they can in- commode, vex, and even destroy the woman by degene- rating the womb, the ovaries, or other parts, they can likewise subvert her health, and destroy her life by per- verting the strength and soundness of other vital por- tions — the radiating point of the mischief being, in the mean time, concealed within the depths of the pelvis, and wholly masked by the constitutional disorders thus set on foot by it. A dark and mysterious veil hides from us many of the laws that grow out of the intimate relation and mutual dependency existing between the conservative or generic forces of animals, and their reproductive or genetic powers. Many stumbling-blocks in the path of the practitioner would be taken away, if these laws and 26 ACUTE AND CHRONIC DISEASES relations could be fully understood ; and we should then be able to take more precise indications, and adopt more positive methods of treatment. Possessing full ana- tomical and physiological information upon those organs and forces, we might raise up in the mind a true ideal of them, which would serve as a standard or scale by which to measure and judge every aberration of form, substance, power, or place, in the instances brought be- fore us for our decision. And it is proper, indeed, that the physician should, in every case of disease, endeavor to acquire the perfect idea of the organ whose state he is about to determine. This determination he only can make, who hath al- ready erected his ideal standard, as now proposed. Otherwise, he cannot but frequently err in his diag- nosis. But he who hath ever at hand in his scientific store, a perfect ideal of the healthy organs, shall scarcely err, since, in every diagnostication, he will strictly compare the real with the perfect ideal, or standard, and, from observing the deviations and aber- rations, deduce a perfect knowledge of the case before him. In order to raise up such an ideal or standard of the uterus, it is necessary to analyze its component tex- tures, and arrange them ; for example, into a series, as : 1. The serous tissue. 2. The mucous tissue. 3. The sanguiferous; 4, absorbent; 5, the muscular tissue. C. The Nervous substance. 7. The glandules and folli- cles. 8. The areolar texture. These are the only things in the uterus that can be OF THE NECK OF THE UTERUS. 27 subjects of disease, whether severally or conjointly. When they are combined in the just ratio of mass crasis and vital force, they represent the form and substance of the healthy womb, and, we might add, its faculties also; whereas, every deviation from such normal ratio of the elementary tissues, represents a certain disease of that organ. Equable augmentation of the elementary tissues con- stitutes hypertrophy of the uterus — which may be either local or general. Hypertrophy of the womb may be physiological or pathological. The term physiological hypertrophy here applies to those equable augmentations of the elements of the uterus, that take place in pregnancy, in which the womb acquires, in the course of 280 days, a greatly increased volume, and a weight of 25 to 30 ounces. In the non-gravid state, its length is about 2i inches : in pregnancy, it is 12 inches in length. The non-gravid weight is 2 J ounces, whereas it, not rarely, weighs two pounds, at term. These great changes occurring in the mass, while inconsiderable changes in the ratio of its elements take place, can only be the result of a physio- logical hypertrophization — and it is well to make such a reflection, seeing that the womb recovers its non-gravid form, substance, and faculties, in about thirty days after the termination of pregnancy. In this process of Normal-hypertrophy, the several elementary textures are evolved in their equal gene- rical ratios ; and the same kind of equable development 28 ACUTE AND CHRONIC DISEASES takes place in all the cases of true pathological hyper- trophy. As the womb readily recovers from any physiological hypertrophy in about thirty days after the removal of the cause, so, in like manner, it recovers from its patho- logical hypertrophy soon after the removal of its cause. Such cause may be a polypus developed within the cavity ; chronic inflammation of the cervix or os uteri ; dislocated states of the uterus, in retroversion, or ante- version ; or any circumstance that should provoke the organ to grow inordinately, but equably, as to the ratio of its elements. Unequable development of the several elements, converts the womb into a Tumor, degenerates it, and renders it incurable by medicines ; whereas, the state of pathological hypertrophy is one to be recovered from upon removal of the cause. If, in a womb, the areolar or the vascular, or the nervous element, should be augmented several hundred per cent, beyond its normal ratio, the rest of the tissues preserving their quantitative relations to each other, the viscus would be changed into a hematoma, a ce- phaloma, &c. &c, according to the nature of the case or chief constituent element of such tumor. Unhappily, the womb is, by nature, peculiarly sub- ject to such changes. It may pass unharmed through the hypertrophizations and recoveries of many conse- cutive pregnancies, because of its innate aptitude to recover its non-gravid form and substance by involution as the antithesis of its acts of evolution ; a reflection OF THE NECK OF THE UTERUS. 29 this that affords us the greatest encouragement when called on to undertake the treatment of cases of en- larged womb. So true is this, that, in all cases where we can clearly diagnosticate a uterine hypertrophy, we may found on it a happy prognosis, provided we may also reasonably expect to remove the cause of the ex- cessive growth, e. g. if the cause should prove to be a mere retroversion, we may count upon a cure if we can reposit the womb and maintain it in its proper attitude in the pelvis. This is, in fact, all that we shall be called upon to do; for, this being done, the organ hastens to recover by involution its non-gravid form and substance, as after a delivery at term, or after an abortion. A perfect ideal of the normal womb, one fit to serve as a standard, or scale of comparison or measurement for cases, should comprise, in addition to a notion of its elements, one of its form, volume, place, posture in that place, sensibility, resistance, complexion, and all its powers as well as its anatomical relations or connec- tions. A great help to the formation of this ideal standard, may be found in drawings and engravings. And here we beg leave to submit a figure (Fig. 1) copied from nature. The womb, which was that of a young un- married woman, was 2 \ inches in length, by If in width at the widest part. Its weight might be 2 h ounces. The specimen, a recent one, was presented to us by Dr. Addinell Hewson, of Philadelphia. "We re- gard this uterus as a fair standard specimen. 30 ACUTE AND CHRONIC DISEASES In respect to this drawing, and indeed all the figures made use of as illustrating points treated of in this essay, we owe an apology for their want of artistic excellence. It is clearly out of the question that we should show these things to artists, as well as that no artist could represent them from mere description. We did try that experiment, which failed. We were then compelled to become artists in self-defence, and suc- ceeded, as is here to be seen, in making very inelegant, but very faithful representations of the subjects of the sketches. As to their fidelitj' we have no other assur- ance to give than such as we may refer to as profes- sional experience ; and we feel assured that all those physicians who have been obliged to acquire this pain- ful experience must concur in the opinion that our drawings are very truthful. This figure, it is therefore believed, gives a fair ave- rage representation of the form and size of the human womb. The chirurgical neck projects within the re- mains of the vagina, to the normal depth ; and the aperture, or os uteri, preserves its appearance as a transverse sulcus. Fig. 2 represents an antero-posterior section, and ex- hibits the left symmetrical half of the womb ; showing the thickness of the walls, in this direction ; the size and shape of the cavity ; as well as those of the canal of the neck ; the two lips, anterior and posterior ; and the length of the vaginal neck or surgical neck. Fig. 3 is a transverse section of the womb, exhibiting the posterior half, with the shape and size of the OF THE NECK OF THE UTERUS. 31 cavity; as well as the canal of the cervix, and the orifice as seen in this way. Fig. 4 is designed to give an idea of the womb's place and position or attitude in the pelvis. It is on a scale of half an inch to the inch ; and shows how far below the plane of the superior strait (see dotted line) the fundus uteri should be found. Most of the published drawings have erroneously exhibited the fundus uteri rising as high as the plane of the strait, or even elevated somewhat above it, which is incorrect, and leads to considerable errors in diag- nosis. Considering that the plane of the ischium is oh inches long, and that the mean length of a normal womb is about 21 inches, the figure may serve to give a correct idea of standard as to place and altitude, since the diagnosticator, by touching the os tincaB, at once recog- nizes the place in the excavation where it is found, as whether too high, or too low, and he also determines, by palpation at the hypogastrium, whether the fundus is too much elevated or no ; and so he judges of the length and volume of the womb he is examining. The anatomical relations of the womb are those which unite it with the bladder in front ; the vagina inferior- ly; the broad and the round ligaments, ovaries, and Fallopian tubes at the sides and angles; while, poste- riorly, it has no anatomical relations whatever; that surface being there completely invested with a peri- toneal covering. The standard should comprise a true idea of the os 32 ACUTE AND CHRONIC DISEASES tincse or aperture of the canal, many deviations from the standard being observable in practice ; all of which may afford useful lights in diagnosis, prognosis, and practice : certain changes of its form may be regarded as pathognomonic. The sensibility of the uterus to pressure or contact ; its resistance and flexibility, ought also to form part of the ideal ; and lastly, the color or tint — as observed in the metroscope — as whether pale, rose-tinted, raspberry- red, violaceous; or even of a hue approaching to that of melanotic tissues, constitutes an important item in the aggregate of characteristics. Experience has shown that many instances of bad health are to be attributed to acute or chronic ailments of the womb, in women, where no topical pain or other sign of local lesion is complained of. Thus some of the examples of perverted innervation exhibited in torpor of the bowels, chronic tympanitis, frequent attacks of spasm, and general convulsion ; ce- phalalgia, palpitation of the heart, pain in the back loins and lower extremities ; fluor albus, and aggravated hydrsemia, take their origin from disease of the cervix uteri, which, meanwhile, gives no pain, and is wholly un- suspected as the subject of any disease. In so far, there- fore, as these affections spring from acute and chronic disease of the neck of the uterus, they might be assumed to come within the scope of inquiries assigned to this essay ; but since an elaborate statement of all those sub- OF THE NECK OF THE UTERUS. 66 jects would fill a volume rather than this essay, we shall confine our remarks within narrower limits. Among the number of sexual disorders, few are more frequently complained of than leucorrhoea, and it seems probable that most women have occasion, at some period of life, to complain of it. In general, it gives little in- convenience, is of short duration, and ceases sponta- neously; not requiring for its cure the advice of physi- cians. Perhaps in a thousand cases of moderate fluor albus, the physician would be consulted for one or two only. This, however, is not the case always, for in cer- tain exceptions the secretion becomes very great, and is attended with debility, pain in the back and loins, a sense of bearing down or weight in the pelvis, with heat in the passages, which may pass into insufferable pruri- tus. Instances in which the profluvium is very great, will rarely be met with in any physician's practice ; and not many of the subjects are found to require the use of the guard-napkin, a precaution which could not be dis- pensed with if the secretion were so abundant as is by some supposed. We have heard of cases of leucorrhoeal discharge to the amount of eight ounces per day, but probably such examples occur not more than once or twice in a long career of medical practice ; one in Avhich the secretion should equal a tablespoonful per day, even, would be very troublesome, as well as uncommon, the majority of the patients complaining only of an in- convenient humidity of the parts. Where the discharge in leucorrhoea consists of merely vaginal products, it may safely be assumed that such 34 ACUTE AND CHRONIC DISEASES leucorrhoea is of very little consequence to the woman's general health. We speak here of the moderate cases. Indeed, affections of the vagina may, for the most part, be considered to interest very little the female constitu- tion. Such a statement as this might excite surprise, in those who are accustomed to hear of the very debilitat- ing effects of fluor albus ; and it becomes necessary to qualify the statement, by showing that, in those cases where the health has appeared greatly to suffer, the essential malady is not in the vagina, but in the neck of the uterus itself. Patients do not, in general, make any discrimination between the several different appearances presented in fluor albus ; because they are satisfied to believe that excessive humidity of the genital mucous surface is fluor albus, or vaginal leucorrhoea, a disorder whose pre- sence disturbs them, not only by the actual inconveni- ence occasioned by it, but in a more considerable degree by the apprehension it arouses of prospective mischiefs to their health. While our own observation convinces us that profuse vaginal secretion is rarely met with in practice, we are equally convinced that some of the patients are rendered too moist by excessive activity of Duverney's glands, and farther, that the most mischievous of leucorrhceal secretions is that which comes from the canal of the cervix of the womb. The muciparous glands of the vagina furnish either a thin watery mucus, or else one of a creamy consistence, OF THE NECK OF THE UTERUS. 35 which in other instances appears to be butyraceous, or concrete. The excretion from the follicles and glands of the canal of the neck, however, is always gluey or albuminous, and resembles fresh white of eggs ; and, when the patient, in describing the disorder, informs us that she discovers a slimy transparent mucus, and especially if it appears at intervals of once a day, or oftener, we may take it for granted that she labors under inflammation of the neck of the womb. There is no apparatus in the vagina itself for the secretion of this albumen ; but the abun- dant follicles of the canal of the cervix are devoted solely to such production — when the cervix is chroni- cally inflamed, that production is much increased ; to that degree, indeed, as to impart a character of sliminess to the discharge, that makes it resemble albumen ovi It very often happens to observe this transparent vis- cid mucus to be wholly unaccompanied by any vaginal excretion; the substance coming away from the os uteri, and escaping upon the napkins without the least admix- ture. In using the metroscope, the same albuminous matter may be seen oozing forth from the orifice of the womb only, and so tenacious that it cannot be wiped away with the sponge. Those physicians who have attended women in la- bor, are familiar with the viscous excretion from the neck of the womb, which generally discharges consider- able quantities of it while the os is undergoing dilatation. In a state of ordinary health, the production — which is equal merely to the physiological demand — is so incon- 36 ACUTE AND CHRONIC DISEASES siderable, that the albumen is not to be observed ; but any augmented vital activity in the cervix may make its presence manifest. It has already been remarked that subjects of leucor- rhcea complain of it as a weakening disorder ; nor can it be denied that this albuminous fluor from the cervix mostly coincides with a sense of great lassitude and de- bility — not because of the wastage of the material, but because of the disturbing effect in the general economy, produced by even slight modifications of the health of the uterus. Hence I may venture to say, that those women who complain of the exhausting effect of their leucorrhoea, should be regarded as suffering, not from the loss by secretion, but from the perturbating influ- ence of a chronic inflammation of the womb. Physicians consulted for these leucorrhceal affections, ought, therefore, carefully to discriminate between the different kinds of discharges. When the excretion is deemed to proceed from the muciparous apparatus of the vagina only, it may suffice to make astringent injections, whether of mineral or vegetable sorts. In case such re- medies prove unavailing, the vital activity of the mu- cous body may be changed by solutions of argent, nitrat., of feeble strength — and one might confidently look for a cure under such a prescription. Yet, in fact, our ordi- nances for those disorders are notoriously unsuccessful ; and the reason is, we vainly attempt by these methods to cure a disease of the vagina which does not exist, which would not make the woman ill if it really did OF THE NECK OF THE UTERUS. 37 exist ; whereas we ought to be addressing our remedies to the removal of a disease of the cervix. We should cure a much greater number of leucor- rhoeas if we would not misinterpret the disorder, call- ing that a vaginal which is really a cervical malady, and vice versa. We repeat, that the serious cases are cases of disease of the cervix — but, a vaginal injection for inflammation of the canal of the neck, is, simply, ridiculous. The albuminous leucorrhcea is a sign of inflammation of the cervix, in which is included the canal, with its copious muciparous apparatus. It is as much a surgical dis- order as an ulcer of the leg, or an anthrax, or conjuncti- vitis. When the surgical disorder is cured the sign dis- appears. Hence we desire to express the opinion, that such leucorrhoeas are to be held as acute or chronic in- flammations of the canal of the neck, and ought to be treated accordingly. The most essential element of a successful practice exists in a positive diagnosis. It will not do for us to believe, or suspect, or infer, this or that — we must guard the interests of the patient by knowing it is this, or that, or the other form and stage of a disease. The historical or descriptive account delivered by the patient, or her friends, cannot serve as a guide for us ; nor can they compare the actual state of the suffering organ with that perfect ideal standard, by which we ought to compare, weigh, and measure everything brought before us for judgment. It must ever be a very trying occasion, that of a sensi- 38 ACUTE AND CHRONIC DISEASES tive and delicate woman, who is brought into such a strait as to require a physical examination of those parts which naturally shun exposure. The medical man, who has even a common share of sensibility, will al- ways, therefore, defer this last resort as long as possible, while he makes use of empirical treatment — if, haply, he might thus be enabled to effect a cure without the waiver, on her part, of those honorable scruples which deserve from him the most perfect respect. Of all the means of making a physical diagnosis, Touching is the easiest and the least distressing to a woman of sensibility, bad though it be. By Touching, we can determine the place, the volume, the resistance, the sensibility, the smoothness or roughness, the patu- lousness, and other characteristics of the organ. Where the touch gives sufficient information, let the Touch suffice ; but, if any doubts as to the wants of the case remain, then a Metroscopic examination should be made. If declined — let the consequences rest with the patient ; the physician is absolved from blame. There are a great many sorts of Metroscopes now in use — some consisting of a tube, as originally proposed by Recamier, but composed of glass, or silver, or ivory, &c. ; and some consisting of a bivalve, trivalve, or quadrivalve Speculum uteri, each of which is pre- ferred, according to the taste or caprice of the practi- tioner. The most reliable metroscope, probably, is a slightly conical tube of silver, six inches and a half in length. The uterine extremity should be one inch in diameter, OF THE NECK OF THE UTERUS. 39 bevelled with an angle of thirty-five or forty degrees. The outer, or larger extremity, should be one inch and a half in diameter. The silver should be highly .polished, with the edges of the bevelled end rolled and rendered blunt, lest they might catch in the folds of the membrane, or even wound the cervix. An olive-shaped piece of wood, secured in a steel handle, and made to fit accurately in the smaller ex- tremity of the cone, serves to guide it without pain to the bottom of the vagina, whereupon the guide is with- drawn, in order that the Surgical neck may engage in the opening, and thus enable the surgeon to discern any marks of disease there. The light passing down the tube ought to be as clear as possible, and the- inner surface of the metroscope should not have a very high polish, lest, serving as a reflector, it might pour a flood of chromatized light on the parts, and thus give rise to the greatest misappre- hension of their real condition. It would be better to have the inner surface painted with black, in order that no reflection from the walls should deceive us, and lead to error. Any person accustomed to the use of the me- troscope with a very bright inner surface, or bore, must be familiar with the sparkling red points that it seems to disclose upon the mucous surfaces exposed by it to view, and also, must have seen how a slight change in the direction of the tube, causes these red lights to disappear ; but they are always apt to mislead, and therefore it would be better to use a tube whose inner surface should have no lustre : a tube blackened within, 40 ACUTE AND CHRONIC DISEASES like a microscope tube, would be far better than one with a reflector, such as the glass speculum uteri. An instrument on the plan above proposed can dis- close the physical appearances of any square inch of the inner walls of the vagina; for by merely rotating the tube on its axis, and directing the bevelled end this way or that, we may at leisure observe any part of the cervix or vagina. The bivalve and the quadrivalve speculum are some- times convenient ; but they as often annoy us and ob- struct the research by allowing folds of the vagina to fall in between the parted blades, and thus completely hide the parts sought to be studied. They are by no means suitable for the application of the cautery, whether liquid or solid ; and no one could conveniently make use of leeches by means of them. In any case, where the multi valve speculum is applicable, M. Recamier' s tube is more so, on which account, we prefer it alto- gether. Plate 4 represents a Recamier metroscope, with its guide. This instrument is of silver, and bevelled in a way to facilitate the operation, in engaging the os tineas in the open end of the tube, which readily catches the cervix by its projecting long lip. It has not any handle, a thing that, moreover, is both useless and troublesome by catching in the bed-linen or the nap- kins with which the patient is always to be enveloped on such occasions. With a Recamier tube, one can readily observe any, even slight modifications of form or surface, hue, abra- OF THE NECK OF THE UTERUS. 41 sion, vegetations, druses or botryoiclal excrescences. Small polypi, jutting from the canal of the neck, any fissures or rhagades, ulcerations, cauliflower degenera- tion, or open carcinoma, &c. &c, that shall have given rise to the symptoms may be thus seen. The same occasion may be seized to make such surgical dressings as may be indicated, and the sacrifice of sensibility in this way made by the sufferer, is almost sure to be re- warded by a speedy cure of any curable disorder, which, but for such sacrifice, would continue to make her un- happy, leading, by a perpetual progress of deterioration, to ruined health, and, finally, to the last refuge of the miserable, which is the tomb. A diagnosis by the metroscope should be made in the daylight, and always in presence of a third person. The patient should lie on the back, near the side or foot of the bed ; the head, and not the shoulders, rest- ing upon a pillow. A sheet or spread is to cover the person ; the margin of the covering to descend nearly to the floor. The knees should be much flexed, and the feet near to the trunk of the body. Before proceeding to adjust the instrument, an exa- mination should be made by Touching, to ascertain the precise position of the uterus, and the place occupied by the cervix ; the sensibility, resistance, volume, &c. of the neck, and particularly, the state of the aperture of the womb. There should be provided a Speculum-forceps, and some small bits of moistened sponge, or carded cotton, 42 ACUTE AND CHRONIC DISEASES which, being held in the forceps, serve to absorb or remove any mucus or slime, or sanguineous excretion. The most convenient Speculum-forceps that can be got is probably a bullet forceps ; such as the one proposed by Professor Gibson. The Speculum-forceps of Charriere is far less conve- nient. If the Metroscope should now be adjusted beneath the coverings, and the margin of the sheet be afterwards care- fully wrapped around the outer end of the cylinder, it will be easy to conceal, in this way, the entire person of the patient, while the light falling down the tube, serves to reveal any existing signs of disease of the parts to be examined. If these inquiries are instituted for the purpose of determining the precise cause and learning the proper treatment of a troublesome leucorrhcea, especially one characterized by the albuminous discharges heretofore mentioned, we shall rarely fail to observe a positive inflammation of the cervix and os uteri, or to notice a certain quantity of transparent viscid phlegm, oozing slowly away, or tamponing the orifice of the canal of the cervix. One or both of the lips of the womb may be found tumid, softened, granulated, or botryoidal in appear- ance, and of a uniform red ; or else drusy as to the sur- face, and presenting some resemblance to the surface and color of a ripe raspberry; whence it has been the custom of some to speak of this form of inflammation as inflammation framboisee, a French word that very aptly expresses the idea of it. OF THE NECK OF THE UTERUS. 4d Annexed is a drawing (vide Plate 5), by which we hope to impart a correct idea of one of the forms assumed in inflammation of the cervix uteri. It was drawn soon after the inspection of a case that was under the care of the Author. The lad}', about forty years of age, was the mother of several children, of whom the youngest was between three and four years old. She had long complained of weakness, pain, and drag- ging sensation in the back and loins, a bearing down at the hypogaster, and a leucorrhoea, which she supposed to be the whole malady. Her fastidious delicacy in- duced her, for many months, to conceal her uneasiness ; nor did she at last apply for counsel, until her health was very much reduced, and her appearance greatly changed. She had acquired a deep sallow tint of the skin ; had anorexia ; lowness of spirits ; intestinal tor- por; slight d^ysuria, and a constant fluor albus. It was not until after presenting clearly to her com- prehension a statement of the motives for it, that she reluctantly consented to allow a metroscopic examina- tion to be instituted ; and it manifestly appears that none other could have possibly revealed the real nature of her position and its danger. The os tincse of a healthy woman with difficulty suffers the passage of a small female catheter into the canal of the cervix. In this case, the ends of two fingers could be introduced nearly half an inch. The cervix, of course, must be much enlarged to make so great an aperture. But the drawing, which is believed to be as correct as 44 ACUTE AND CHRONIC DISEASES any daguerreotype could be, will show better than words the appearance it presented. Plate 5, which may be compared with Plate 1, will show how enormously this Chirurgical neck and this os uteri exceed in magnitude the one we have presented as a sample of the ideal or standard uterus. The cervix, although so greatly enlarged, and as red as the tint in the drawing, was not exceedingly sensi- tive. Its resistance was neither too hard nor too soft, as is the case in the hypertrophies. The os had the shape or form here expressed. It was enlarged, but not deformed. Had it been deformed, that circumstance alone would decide as to its being not hypertrophy ; because, it would prove that the development or growth was non-equable. The orifice or aperture of the canal was occupied with a viscid transparent slime, which was the albuminous product of sur-excited muciparous glands and follicles, which abundantly line the canal of the cervix. Its ap- pearance is pretty well represented in the engraving. Inspecting the interior of the canal of the neck, as far as it could be observed, the red tint seen on the lips gradually passed into the dark, almost black hue, which, in the figure, approaches to the color of melanotic tissues, and it was of so black a color as to lead the writer at first to fear that it was due to some pro- cess of sloughing. He had never, in any other case, noticed anything similar. This case was treated, by the author, by means of antiphlogistic contacts of the nitrate of silver pencil. OF THE NECK OF THE UTERUS. 45 The number of those contacts, which were reiterated with intervals of from five to seven days, did not exceed six or eight, and as the inflammation vanished before the therapeutical power of the remedy, the womb re- turned rapidly to its form and dimensions; just as it would do, if, being enlarged by gestation, it should be set at liberty, by an abortion, to return to its non-gravid condition. We shall shortly explain the meaning and intention of the phraseology we have employed, as to antiphlogistic applications of the argent, nitratum. The ideal womb is two and a quarter inches long. This specimen was so much augmented in size that, while the os tincse was low down in the excavation, the fundus was distinctly felt above the plane of the supe- rior strait, being at least one inch higher than that. It might, perhaps, be a desirable thing to know, if possible, why it happens that, in certain cases of in- flamed cervix, the surface of the lips of the womb should be smooth or even, as is seen in the present specimen ; while in others, the inflamed superficies become uneven, or tuberculated, or drusy. To show the difference here alluded to, the Authcft? begs to ask attention to the annexed figure (Plate 6), which exhibits the uneven surface in question. This drawing is also copied from nature, and repre- sents an appearance very commonly met with in prac- tice. The Chirurgical neck is manifestly and much enlarged, which does not imply merely swelling of the texture, but rather, a condition of hypertrophic growth or nutritive development. Here, as in almost all the 46 ACUTE AND CHRONIC DISEASES examples, the hypertrophy proceeds from the provoca- tion contained in a positively inflamed state of the corpus mucosum uteri. Such an inflammation is, virtually, an advanced vital ■status, which stimulates the whole organ, and compels it to obey its natural law, which is that it shall wax or increase in substance, equably under certain stimulation. This is the power which enables it to go through those vast but equable mutations of its form and substance that coincide with gestations. One might well, from inspection of such a specimen, deem that the vital status of the corpus mucosum must be dangerously exalted. It exhibits many tubercular elevations, which, however, are soft and velvety to the touch. There was no ulceration ; on the contrary, the entire surface was covered with its pavemented epithe- lium, which was so delicate, however, as easily to be broken by a sponge, or by imprudent, awkward mani- pulation with the tube. Madame Boivin seems to have conceived the idea that a tuberculated surface like this may possibly be the expression of a commencing stage of cauliflower degeneration, and the thought is worthy of attention. The patient from whom this drawing was taken, was rapidly cured, the irregularities of the surface subsiding to the ordinary smooth level, and all the excess of mag- nitude, sensibility, and color of the parts being taken away, chiefly by contacts of the nitrate crayon — in which surely resides a true antiphlogistic therapeutical OF THE NECK OF THE UTERUS. 47 force, as we shall hereafter endeavor to show and ex- plain at greater length. Out of a considerable number of drawings, faithfully representing this appearance of disease in the subject, I have selected these two as sufficient to explain or illus- trate those physical lesions the practitioner may expect to meet with; not wishing to load this essay with a use- less array of specimens. I shall, however, add one more of this class (Plate 7), taken from nature, in a patient who had, for a long time, and in vain, been sub- jected to treatment by nitrate of silver cauterizations. It also presented the appearance, like that shown in Plate 5, of a collection of albuminous mucus in the orifice. As here, so it often happens to observe this mucus-production to be greatly augmented; whereas, in other samples closely resembling it in certain patients, this peculiar sign is either not seen at all, or in indif- ferent quantity. It may well be supposed that variable degrees of vital excitement in the muciparous apparatus, might, for one individual, or now, cause excessive production, while at another time, or in another case, it should give rise to no excess in the albuminous production, and thus we may justly infer that this albuminous discharge is not invariably present as a pathognomonic characteristic ; but on the contrary, the inflammation is the thing to be considered, treated, and cured, if we would really restore the patient's health. When the albuminous discharge is seen, it is, however, always pathognomonic of the cervical inflammation. 48 ACUTE AND CHRONIC DISEASES The Author respectfully submits, that these illustra- tions are sufficient to confirm his assertion, precedently made, that diagnostication by M. Recamier's method is indispensable for the correct information of the medical attendant. Not only do they show how concise and absolute such a diagnosis may be; but they must con- vince that diagnosis, by touching alone, could not convey to the mind so precise a notion of the surgical and medi- cal wants of the sufferer ; while they, farther, manifest the facility, convenience, and exactitude, with which surgical dressings and other treatment may be made by the metroscopic method. Whosoever should examine these illustrations might be expected confidently to infer that so considerable an inflammation as either of them represents, would be likely, not only to give rise to the constitutional dis- orders attendant upon many examples of leucorrhoea; but he would also understand why, along with the albuminous fluor, there might arise an excessive vaginal secretion, which, nevertheless, would be but one of the accidents of the principal case. Daily experience convinces that multitudes of sick women are treated by professional and other persons, for affections like those here portrayed (without the least inkling of the truth), with vaginal injections of various astringent and other solutions and infusions, which rarely produce any good effect upon the health; though they serve, in many, to add to the mischief. It would certainly be a considerable step in the pro- gress of clinical medicine, were it possible to clear up OF THE NECK OF THE UTERUS. 49 these obscurities, and banish from the art the mere senilities which so much discredit it; but this can only be done by means of perfect diagnostications. I beg to repeat that physicians, in order that they may make proper ministrations, require — not belief, but knowledge of their cases. Where perfect knowledge of the case can be obtained, there will be the most perfect administration; there will be, at least, the meliorations; and, in so far as remedies can succeed, there will be the most successful results or cures. A medical man, ordering injections for such disorders as are here described, will assuredly be baffled, since no such injections can be supposed to pass bej'ond the limits of the vagina itself. They cannot penetrate into the canal of the cervix. They bedew only the mam- millary part of the uterus, while they bathe the entire of the vaginal walls. It is the custom of many prac- titioners, to order vaginal injections, composed of solu- tions of argent, nitrat. of various strength. Few of them, we are persuaded, can say they have found much advantage to the patients from this operation. If the Author is to be justified in asserting that the major part of these cases consist, essentially, in disease of the cervix itself, and not of the vagina, which is only secondarily or symptomatically involved in the dis- order — then such a practice is either useless or perni- cious. If such a solution is strong enough, it is too strong; and if it be too dilute, it is indifferent in the treatment, or merely nugatory. The patient requires a remedy for the raspberry- 4 50 ACUTE AND CHRONIC DISEASES colored inflammation of the neck — one fitted to bring to * its close a train of perverted and exalted vital force of an organ, whose disturbance proves to be one of the most considerable disturbers of the constitutional health. The cure of the real disease, the radiating point of disturbance, cures the leucorrhoea, as well as all the balance of the perversions. But, it is proper for us to exhibit other appearances assumed by the inflamed cervix uteri, lest a false direc- tion be given to opinions upon such special cases as may come up in one's practice. We have already ex- hibited several modifications of the cervical surfaces observed in different specimens, and we here call atten- tion to one represented in the annexed figure (Plate 8, Fig. 1), one that is not quite so common as the inflam- mation framboisee, yet so common as to be often met with in practice. The appearances here exhibited (Plate 8, Fig. 1) were those observed in the case of a lady from a distant city, who was addressed for treatment, to the writer, by a distinguished member of the Profession. She had been for a considerable time under his own medical care, after having undergone a great variety of surgical and medical treatment by others, but without any use- ful effect. She complained of pain in the interior of the pelvis ; and of disordered menstruation, which was both menor- rhagic and painful, as well as irregular in its returns. She had dysuria; pain in the middle of the sacrum, and tenesmus : she was excessively hydrsemical and de- OF THE NECK OF THE UTERUS. 51 sponding, and had capricious appetite; while acidity and torpid bowels accompanied the affections above enumerated, and, to crown all the rest, she was fre- quently attacked with what might be called crispations, or rather spasms and convulsions, simulating closely certain epileptic forms. The nervous system was in a state of such sur-excitement, that a word, a look, an emotion, or any motion of the limbs, often served to render her quite insensible from an attack resembling a slight form of puerperal eclampsia. She had borne three children, of whom she had, within a year, lost two by scarlet fever; and that event, by the moral shock it occasioned, had greatly aggravated all her pre-existing complaints. The womb was retroverted; the fundus resting in the Douglass cul-de-sac, while the os was near to the symphysis pubis. Upon exposing the chirurgical neck to a beam of day- light, by means of the Eecamier tube, the os proved to be inflamed, with the margin of the anterior lip tinted red, just as is here shown; while the lower lip was covered by a disk of inflamed corpus mucosum, of a square shape ; the whole of this square patch was evi- dently a raised surface. One might almost venture to call it a molluscum on the cervix. It is frequently met with in clinical practice in sexual disorders ; and we think always exhibits this peculiar character. Its frequency in practice, we repeat, is considerable. In reasoning upon such a case, it would seem super- fluous to look beyond facts, like these as here stated, 52 ACUTE AND CHRONIC DISEASES for a rationale of the constitutional and local pheno- mena. The healthiest young married woman is liable, almost immediately after conception, to be affected by those disturbing radiations of the uterine or hysteric force that are developed by the new vital states of pregnancy, and she may soon be seized with distressing nausea, or frequent vomiting, or profuse salivation; with anorexia, hydrasmia, hysterical passion, and a thousand perversions both of the reason and the senses, as well as of the organic functions. If the hysteric malady, with its incoherent train of vital manifestations, may arise out of a basis of repro- ductive irritation, even less considerable than that of an incipient gestation; we really are not called upon to look farther for causes of the constitutional symptoms of our case than to those morbid states of the womb that are here set forth in the figure 9. As to the treatment, the fundus uteri was lifted up out of its false position, the cervix was thrust back to its place near the sacrum (see the ideal standard, Plate 3), and retained in it by means of an annular pessary, whose sacral segment rested in the posterior vaginal cul-de-sac, and its pubal segment against the pubis. Nothing could now retro vert it again. To take the womb thus out of its dislocated position would, alone, go far towards insuring its recovery; and it will be presently contended that many of the uterine diseases, even great hypertrophies, require no farther treatment; but being thus delivered over again under dominion of their natural or generical laws, they hasten OF THE NECK OF THE UTERUS. 53 to recover their true generic substance and form, by in- volution, as after parturition. In this instance, however, the disk of inflamed tissue was treated by antiphlogistic contacts of argent, nitrat., by which it was cured; and thus provision was made for the early removal of a cause of the constitutional disorders, additional to the displacement cause. Having repeatedly spoken of contacts of the nitrate of silver as antiphlogistic contacts, it seems proper now to explain my meaning in the use of that phraseology. It is undeniable that a pencil of nitrate of silver ap- plied to a soft, moist, living tissue, and held long in contact with it, will disorganize the tissue, and so prove to be a destructive contact. It is equally undeniable that a contact may be effected with such rapidity and lightness as to prove ineffective or indifferent, while there is another mode or force which does resolve in- flammation with great certainty; and this is the anti- phlogistic contact above spoken of. "We therefore feel warranted to speak of such use of the nitrate of silver as being either destructive, or indifferent, or antiphlo- gistic contacts; and experience confirms the propriety of the classification; for, we meet with numerous examples of treatment that conclusively prove it is not the mere treatment by escharotics that is successful, but the use of them in such a way as to provide for their due opera- tion as antiphlogistics and not as destructives ; for as any ulceration of the mouth of the womb is a thing of very rare occurrence, we do not require, in the case, the use of destructive contacts of the salt of silver 54 ACUTE AND CHRONIC DISEASES or other escharotic, but only their curative or antiphlo- gistic power — a power which is perhaps really due to their contro-stimulant faculty. Certain women, who are in vain treated for these cervix-inflammations, for months in succession, by contacts of nitrate of silver, recover their health very speedily upon a few such an- tiphlogistic or contro-stimulant touches, lightly made — that is, made with due regard to the resolvent or an- tiphlogistic power of the drug. It is not enough, there- fore, in studying this subject, for the practitioner to resolve upon the treatment by a method of escharotics or cauterizations, as it is erroneously expressed. Far from it — what he requires is, to create for himself an ideal of his operation, so that, when about to perform it, he may predetermine what it is he hath to do, and whether the contact he is going to make shall be a de- structive or an antiphlogistic one. It might equally well be called a resolvent one. He who fails to set up before him this ideal of his duty and pur- pose, will be apt to fail in the cure; or his cure will be a chance-medley and not the product of a rightly reasoned purpose and conformable act. This absence of precision in the design and act fre- quently occasions the greatest and most dangerous aggravations, and the most poignant sufferings — which, in our estimation, is wicked and abominable. They are disgraceful to the Art and the artist at once. Believing these remarks to be both just and clinically important, it is desirable they should arrest the atten- tion of every practitioner in this line. OF THE NECK OF THE UTERUS. 55 After the foregoing observations, we will now aver that, by means of antiphlogistic contacts of the nitrate crayon, it is possible to cure, and that speedily, most of the inflammations, and their accidents met with in this humble department of clinical medicine or surgery; for it is to be remembered that few of them are attended with any, the least degree of ulceration, as we have before asserted. It is a common opinion, and it is generally agreed to say so, that these are ulcers on the womb; and there are people who seem never to fail to discover an ulcer upon making an examination with the speculum ma- tricis. An immense experience in a populous metropo- lis — an experience greatly increased by the resort of numerous invalids from the country, and from the dif- ferent United States — enables me with confidence to declare, that an ulceration of the womb is among the rarest of disorders. I repeat the expression of my opinion, that these disorders and framboisee inflamma- tions and hypertrophies of the cervix, have been misin- terpreted and accounted as ulcerations, which they. were not, the superficies being covered with a delicate epithe- lium, yet so very delicate as readily to give way and suffer abrasion under improvident, unskilful manipula- tion with the tube or the sponge. A proper antiphlogistic and resolvent contact of the crayon ought not to destroy even this delicate epithe- lium; but rather to make it more firm and dense, and so planish, as it were, the unevenness down to the normal surface level. In this way, we may compel the 56 ACUTE AND CHRONIC DISEASES drusy or tubercular eminences to sink down again to their place, and, by solidifying the epithelium, give a firm physical delimitary support to the before debilitated capillaries that rose up in the form of a soft molluscum. My patient was thus treated. She was also advised to take abundantly a nutritious diet, with a copious al- lowance of Bordeaux wine and water; to swallow, soon after each daily meal, two grains of iron revived by hy- drogen, and made into a pill with clarified honey ; to get into the open air, on foot, as much and as long as possible, and, being a person inclined to follow the in- structions, she soon recovered a good state of health. As incidental to this part of our explanations, it may be proper to remark, that the state of the canal of the cervix so often referred to, is, in all probability, one of the ordinary causes of sterility. In examining these structures after death, we have observed the whole cylinder of the canal of the cervix to be filled or tamponed, so to speak, with a plug of viscid lymph, so obstructing the passage as to render it apparently impossible that any spermzoon could obtain access to the uterine cavity. Certain it is, that some sterile women are always affected with this excessive albumi- nous mucous production. We have met with instances of unrelieved sterility in women enjoying the most robust health, with the sole exception of this vexation, which never gave any pain, nor modified the mensual phenomena in the least. Many women, who had tem- porarily suspended the usual succession of their gesta- tions, apparently in consequence of this derangement of OF THE NECK OF THE UTERUS. 57 the health, have again conceived after the cure of the albuminous leucorrhcea; or rather, the inflammation of which it was the sign and consequence. Surprise has often been expressed on observing that married women, after years of sterile cohabitation, have suddenly become fruitful. In these instances, the want of fruitfulness could not depend on failure of the ovu- lations ; may it not be that the spontaneous cure of a protracted and subacute inflammation of the kind herein treated of may have restored the health, and so given power to take away the woman's reproach ? Continuing the plan adopted in this essay, we now observe that other forms of cervical inflammation, than those already described, will present themselves to the observation of the clinical practitioner ; and we submit the accompanying drawing, taken from the life, in a case which proved unexpectedly rebellious to treatment, though it was subdued at last. This person, a lady of small stature and delicately formed, of a sanguine choleric temperament, had given birth in rather too rapid succession to six living child- ren, and experienced, in the third lying-in, a very dan- gerous attack of childbed fever ; and, a few years later, subsequently to the birth of her sixth child, suffered from a severe crural phlebitis, or milk-leg. The health had been less firm than usual after her recovery from the phlebitis, although she was not afterwards, on ac- count of her valetudinary state, confined to the house. After, for a long time, patiently enduring severe pains, referred, in chief, to points in the neighborhood 58 ACUTE AND CHRONIC DISEASES of Poupart's ligament of the left side, with distressing sensations in the range of the external obturator nerve, bearing-down feeling, backache, debility, loss of appe- tite, irregular action of the bowels, and dysmenorrhceal symptoms, she asked for advice. There was incon- siderable fluor albus, no positive dysury, nor other sign of uterine deviation or displacement. Exercise on foot invariably increased the pain, and the jarring of car- riage-springs was highly annoying. She looked dispi- rited and wan. Touching the chirurgical neck, it was found to be excessively solid, with the posterior lip not a little longer than its fellow. The touch gave, from the resist- ance, the idea of scirrhous induration; and was so painful, even on slight pressure, as to be very unwill- ingly borne, and then, not without some exclamations. The left angle of the os was sulcated — as if it had recovered imperfectly of some foregoing laceration in labor. Pain excited by this pressure was felt not only at the point of contact, but severely in the left groin and inner side of the thigh. The lady submitted, under advice, to an examination by the metroscope, and it disclosed the form, size, and hue, portrayed in the figure (Plate 8, Fig. 2). A long familiarity with maladies of this class, did not prevent the writer from having repeated misgivings as to the result of this attack; which again and again seemed to take upon it so many threatening characteristics of car- cinoma, and resisted so obstinately the most careful, reasoned, and persevering treatment, that, even now, OF THE NECK OF THE UTERUS. 59 he is led to doubt if the case was not strongly tinctured with the malignant nature in question. It was treated with antiphlogistic contacts of the nitrate crayon, with emollient injections of flaxseed mucilage, with anodyne enemata, containing, each, forty drops of tinct. opii, at bedtime, with repeated applica- tion of Swedish leeches to the cervix ; with a regulated diet, occasional baths, a soluble state of the bowels; much rest on the sofa, and the use of hydriodate of potassa, combined with comp. syr. sarsa. Of several hundred cases of inflamed cervix (at vari- ous times, for many years) under treatment, this ap- peared to be the most irresolvable. Yet it began at last to give way, and slowly yielded — so completely, that the patient was advised to take a course of the waters at Saratoga ; from whence she returned in good health, after an absence of a few weeks. Since that time she has passed through a healthy gestation, and has given birth to a robust infant with the easiest of all her labors. During the dilating processes of the labor, the whole cervix was found remarkably healthful. The recovery was fortunate ; and, she has very good reason to rejoice that M. Recamier has taught the profession not only how to make a physical diagnosis, but also how to treat these dreadful cases. We repeat here, that an inspection of our drawing will communicate an idea of the physical appearances, wellnigh as correct as the direct observation of the inflamed cervix itself. It cannot well be believed that such a form of inflamma- tion as this could be made amenable to a treatment by 60 ACUTE AND CHRONIC DISEASES mere vaginal injection, by alterative doses of mass, hydrarg., by preparations of iodine or tartar of anti- mony, or any other merely constitutional medication. It is true that, in some instances, the topical applications may have been either incline rent, or positively injurious; and it must ever happen, that even where one forms in his mind a correct ideal of the therapeutical purpose and act, he may err in the realization of it. It can only be said, that the treatment rarely gave rise to other pain than what was caused, sometimes, by pressure of the instrument. But every sensible pressure with the index finger gave as much. Be this as it may, the ultimate final resolution of a detestable inflamed induration of the cervix, and her complete recovery, furnish proof, that the method (if not a safe, or a desirable one) is, at least, in some very unpromising instances, crowned with the happiest success. The author having already set forth, in a preceding part of this paper, his views in relation to hypertrophied states of the womb, and the constitutional proneness of that organ to undergo hypertrophic development, he will now beg to call attention to some of the consequen- ces of uterine irritation, that differ, at least in form, from those already adverted to and illustrated. Women, who complain of intrapelvic pain, and other disorders of the lower part of the body, are inclined, in general, to account for these incommodities by refer- ring them to, what they call, womb-complaints. This term is so vague and imprecise, that the pronouncing of OF THE NECK OF THE UTERUS. 61 it rarely excites any clear precise idea. Among these cases of womb-complaints, probably none are so common as those which depend upon retroversion of the womb. So frequently does this affection occur in the course of one's medical practice, that one almost acquires a dispo- sition, in every case, before examination, to suspect it has some dependency upon retroversio uteri. The author has long been fully convinced that retroversion of the womb constitutes seventy-five per cent, of all cases of sexual disorders, that are of a gravity sufficient to require appeal to medical advice. This may, at first, appear to be an exaggerated estimate ; but it will pro- bably be found sustained by statistical experience. An inspection of Plate 3 shows how it must happen, that alternating states of fulness or voidness of the uri- nary bladder must interest the uterus, as to its place. An overfilled bladder of urine, by thrusting the fundus backwards towards the sacrum, puts violently on the stretch the ligamenta rotunda ; and, as the uterus is, to a certain extent, rigid and inflexible, it follows, that if the fundus is thrust back so as to stretch the round ligaments, the cervix must come forward, straining at the same time the utero-sacral folds — for the womb moves by the way of see-saw — in being retroverted. A great many women and young girls suffer them- selves to acquire the bad habit of retaining the urine until a large quantity is accumulated within the blad- der. Thirty ounces of liquid, in the urinary bladder, make a mass as big as a quart measure, and it cannot but thrust the uterus injuriously backwards, causing the 62 ACUTE AND CHRONIC DISEASES neck to see-saw at the same time forward, and approach the pubis. A long habit of this kind comes at last to ruin the uterine ligaments; so that the fundus, being wholly overset backwards, sinks down into the Douglass cul-de- sac, while the os takes a permanent place near the sym- physis pubis ; and this is retroversion. It is even some- times a congenital malposition, as shown by Morgagni and others. But, let it be remembered that the womb is con- stitutionally prone to set off on a race of hypertrophic development, and we may then understand how it shall be readily provoked to commence a process of hypertro- phization, by the awkward, unnatural, and irritating posture it acquires in retroversion. We have met with some of these cases in which the womb grew so much that the fundus was jammed against the hollow of the sacrum, and the os against the symphysis, or on the soft parts above it, compress- ing the bladder most mischievously, but not at all bending the womb itself. In other specimens, we find the uterus bent like a retort, as in the outline figure annexed. The angula- Fie. 1. OF THE NECK OF THE UTERUS. 63 tion, in some of the examples, is almost acute ; so that the caliber of the canal of the neck is seriously dimin- ished, and its function as an efferent duct for the menstrua, in a measure hindered ; whence we have dis- tressing dysmenorrhcea. Medical men, called upon to diagnosticate in such cases, should be very careful, first to establish in their minds the ideal or standard, by which to compare ; otherwise they will be apt, upon finding the whole pelvis occupied, or blocked up with an immense and immovable solid mass, to conceive of it as a tumor; whereas it may prove in fact to be no tumor, but only an overset and enormously hypertrophied uterus. We have met with repeated examples of such mis- interpretation of the case, women being supposed to labor under tumors within the pelvis, whereas the sup- posed tumors were nothing more than the posterior aspect of the corpus and fundus uteri, turned over and touched through the posterior membranous wall of the vagina ; and wholly disappearing as soon as the womb could be properly reposited. A young lady was brought to the Author from a distant State, being accompanied by her attending physician. In this case, a drawing was made, after the most careful examination, of which we subjoin a copy — Plate 9. The figure is one-fourth less than the natural size, and is made to exhibit a cross section of the pelvis con- ducted through the pubis and sacrum, with the fifth lumbar vertebra. In making this exploration, it was 64 ACUTE AND CHRONIC DISEASES easy to verify the diagnostic by hypogastric palpation, and by examination conducted both by the rectum and the vagina. The cervix was bent, as in the figure, and the body of the uterus enlarged and turned over deep into the recto-vaginal cul-de-sac. The entire mass was so packed and immovably fixed in the excavation as to make it impossible for one to raise it by any degree of upward pressure with the fingers, and the canal was too much curved to admit of correcting the deviation by using Professor Simpson's sound. In general respects, the patient's health, being not very greatly affected, she was advised to return to her home and undergo at- tempts to reposit the organ by the use of caoutchouc bottles filled with curled hair, a method proposed by M. Hervez de Chegoin. The result has not been commu- nicated to us, farther than to inform us that the lady's health is improved. We have stated this case, because the diagram was made after due reflection, at the time of our consulta- tion, and because we rely upon its accuracy as a repre- sentation of not infrequent cases of disorders of the cervical portion of the uterus. Certainty, we have met with a considerable number of analogous forms of dis- ordered womb for many years past. To reposit the uterus, and maintain it so, would ap- pear to be the chief indication in such a case ; since that alone would be to place it in a condition to obey again its normal or generical law of form and substance. We repeat that a considerable number of instances, in which the womb was greatly augmented in every di- OF THE NECK OF THE UTERUS. 65 mension, in consequence of the irritation superinduced by retroversion, have been treated with the happiest success, on this principle, by the author of this essay. To show how great is the change wrought in the hypertrophied uterus by such reposition, we annex two figures (Plate 10, Figs. 1 and 2). These drawings represent one and the same uterus, Fig. 1 being a view of it when the hypertrophy was at the highest stage ; and Fig. 2, when it had entirely dis- appeared. The patient was a woman 39 or 40 years of age ; her children were all grown up, except the youngest, a daughter, some 13 or 14 years old. When first called to the case, the belly was tumid, and to a considerable degree tense and sonorous on per- cussion, but, with the integuments, so strictly drawn over the abdominal contents as to prevent any satisfac- tory conclusion concerning the state and nature of the substance giving rise to the so great distension. There were dysury and pelvic fulness, with tenesmus ; the menstrua absent, causing some suspicion, on her part, of existing gestation. Touching disclosed a retroversion. The pelvic cavity was so full as to seem packed. The os uteri was higher than the top of the symphysis pubis, and permanently there. The substance of the womb could be traced down and backwards to the hollow of the sacrum. This womb was reposited, completely, and with con- siderable relief. Subsequently, after severe catharsis, it became possible to trace its outline in the belly, and 5 66 ACUTE AND CHRONIC DISEASES Professor Simpson's womb-sound was used, in order to clear up the diagnosis. I next very slowly and cautiously passed the sound into the os uteri, and it advanced with- out giving pain or encountering any obstruction, until the probe-point of it was arrested by coming in contact with the vault of the fundus. The sound had gone six and a half inches into the cavity, which proves that the Fig. 1, Plate 10, is correct as to its length. I am an- swerable that the volume of the chirurgical neck and the orifice are also rightly illustrated, while the trans- verse diameter is as near the truth as I could make it by the most careful measurement, spanning it with the thumb and fingers through the abdominal walls, relaxed after the cathartic operations. The rectification of the position did not, however, save the life of the unfortunate patient, who proved to be also affected with a colloid degeneration of the ovary. This, which became an enormous mass of disease, spread its ravages far and wide within the peritoneal cavity, and she died at the end of six months from the time here referred to, after repeated paracentesis abdominis. Upon making a post-mortem examination, the uterus was found to be of the size and form represented upon the Fig. 2, Plate 10. The case appears to us to present points of great in- terest, since it shows that a vast increase of the volume of the womb, unconnected with conception and gesta- tion, is no more inconsistent with recovery of the non- gravid form and size, than a similar recovery after healthy pregnancy. The measurement, made with OF THE NECK OF THE UTERUS. 67 Simpson's sound, and the opportunity to determine the appearances of the organ, after the death of the lady from colloid cancer, rendered it an extremely favorable example for illustrating the views set forth in this re- port on the subject of uterine hypertrophy. It ought not to be forgotten that this womb admitted of the in- troduction of six and a half inches of Simpson's womb- sound soon after it was relieved of its retroversion, and that the lady perished, some six months later, with de- generation of the ovary and other parts. If, therefore, the hypertrophy of the womb had had any dependency upon the ovarian disease, we should not expect to find it re- duced back to its normal size ; whence we infer that, to relieve it from its dislocated position, was the very thing necessary for its cure. Since writing the above, we have concluded to pre- sent a drawing (Plate 13, Fig. 1), exhibiting the appear- ance of a case of hypertrophy of the cervix uteri, which came under care of the author. It was the case of a maiden lady of some 35 years of age. It is believed that this picture may serve to communicate a correct notion of the physical characteristics of the chirurgical neck in the instance referred to. This patient recovered under resolvent contacts of the nitrate crayon, and the exhibi- tion of internal remedies of an alterative kind. Proba- bly such considerable augmentation as this of the cylin- drical portion of the womb, yet not involving a state of general hypertrophy of the organ, will not be very often met with in practice. Still, cases of the kind are of sufficient frequency to give interest to the description of 68 ACUTE AND CHRONIC DISEASES such a great change in the volume of the neck of the womb. In this instance, and in others much resembling it, we have not been accustomed to detect signs of posi- tive inflammation in the part. Nevertheless, it would be reasonable, from the resolving or deobstruent power of the nitrate contacts in positively inflamed cervix, to infer a similar availability in mere hypertrophic irrita- tion; and practical experience justifies such an infer- ence. Another drawing (Plate 11), herewith presented, shows the appearance of a cervix and os examined by the writer. The patient was a resident of a neighbor- ing State, who, some months previous to her visit to Philadelphia, was visited, at her residence, in consulta- tion. The womb, at that time, was completely retro- verted, and so much enlarged as to fill the excavation j pretty much as it is filled by the presenting part in a labor. It was, at the time, immovable by the hand, but was afterwards slowly raised by means of the caoutchouc bags or pessaries of Hervez : vid. Trans. Acad. Roy. de Med. torn. ii. p. 319. She was con- sidered to be dangerously ill ; but began to recover when the womb was replaced and relieved. After ac- quiring a tolerable degree of health and strength, she proceeded to Philadelphia, complaining of bearing-down pains and intropelvic distress, with catamenial disorder, attributable to the remaining and uncured disorders of the uterus. The metroscope showed the os tincse and cervix as they seem in the figure, in which we have represented the OF THE NECK OF THE UTERUS. 69 organ foreshortened. The unhealthy state of the cervix was attested, not only by its augmented size, the tuber- cular elevations of the margins of the orifice, and the red inflammation, but also by the viscid albuminous dis- charges from the canal of the neck. The treatment consisted, mainly, in the use of anti- phlogistic impressions made by the nitrate of silver pen- cil. The inflammation of the mucous body being cured, the disordered womb returned to its accustomed obedi- ence to its generical law of form and substance, and recovered its normal magnitude. An inspection of this specimen of disorder, remaining after a very great hypertrophy had been reduced, strengthens the inference hereinbefore expressed, that the precise appearances manifested by the os and cervix, in inflammation, are accidental — being either drusy, tu- berculated, or smooth and even in surface ; and now we present a case of hypertrophy, of which Plate 12 is a just and fair exponent of the appearance, as it was examined by us, both by touching and by the Recamier speculum, as well as by M. Joubert de Lamballe's ivory metroscope. The os uteri was of this size, and the cervix could not be embraced within the aperture of the Joubert instru- ment. The neck of the womb, as far as it could be explored by thrusting the fingers upwards all around the neck, in the vaginal cul-de-sac, was of this shape, and flaring out at this rate. The fundus, which was readily detected in the hypogaster, was as high and as ample as is here seen. 70 ACUTE AXD CHRONIC DISEASES The tint of the inflammation of the os tineas is care- fully reproduced in the drawing. The patient had been in apparent danger of imminent death a few weeks before this sketch was taken, and from causes connected with this uterine disease. She is the mother of a numerous family. Some leechings of the chirurgical neck, and repeated applications of nitrate of silver to it, served to cure the cervical inflammation, and the womb returned to the size shown in Plate 13, Fig. 2. The patient was soon restored to health, after several years of the greatest inconvenience and many most painful and alarming attacks endured before this treatment began. No man, much experienced in the treatment of ute- rine hypertrophies, can have failed to meet with persons in whom, to examine by touching, was to find the pel- vis filled up solid, so to speak, with the os uteri close to the pubis. We have met with not a few such instances ; and it has happened more than once, that we have been so much disheartened upon a first examination, as to be prompted to make a diagnosis of incurable disease. In one case, a lady from the distant South, and in the most wretched health, had the excavation so filled up with a hypertrophied and solidified mass, that there was scarcely space sufficient to allow an introduction of the index finger betwixt this mass and the floor of the pel- vis upon which it rested. The neck and os were near the symphysis. It was a case of complete immobility of the uterus, which seemed as big as a foetal head in a labor at term. By means of a Para gum-elastic bottle, OF THE NECK OF THE UTERUS. 71 a very small one, stuffed with mattress-hair, we made an oviform pessary, a little bigger than the thumb. This was forced into the vagina, and retained by an outer compress. In a few days, one somewhat larger was substituted. The elasticity or spring of the caout- chouc bottle steadily pressed the mass upwards, and the size of the balls being occasionally increased, we had the satisfaction to find, after no very protracted service, that the intropelvic tissues had acquired a natural character, and the lady returned to her country in very good health, which she still enjoys. We might relate a great number of cases to show that upon removing the causes of augmented volume of the womb, it falls speedily into its generical habits of nutri- tion, but we abstain, considering that the declaration of this doctrine, indeed, with a few illustrations and expla- nations, ought to suffice to present the matter clearly to the apprehension of any of our intelligent colleagues. It is, by many, very confidently supposed that the use of escharotics in these cervical inflammations will speedily suffice to restore the health of the patient ; and those who are most accustomed to use them, are, per- haps, more thoroughly convinced, than any other per- sons, of their great efficacy. It will not, however, always answer to make the application to the mammil- lary part of the cervix alone, because the inflammation is, in some of the examples, found to attack, with greater or less severity, the corpus mucosum and the mucous follicles of the candlis cervicis. Here it is proper to apply the nitrate by means of Lallemand's port-caustic, 72 ACUTE AND CHRONIC DISEASES or by means of a fitch pencil, which is composed of hairs so rigid that one can readily pass it, loaded with a solu- tion, some distance up the canal. It would be dan- gerous to inject such solution with a syringe whose canula should be introduced within the os. But after all, we must meet with cases, at first to all appearance tractable, that will, in the end, be found to foil our most patient and well-reasoned efforts to cure them. One makes up a diagnosis upon the means or elements of a diagnosis — there is no other way. One cannot, therefore, positively declare what is the state of the tis- sues that compose the walls of the canal of the neck, and it may, and does happen that those tissues undergo changes which render a cure by the means herein treated of out of the question. All the parts that come into view might be apparently little changed, while other parts beyond the reach of sight and touch should be in a very different condition. Here is a drawing taken from a specimen in the author's collection, that illustrates this point. (Plate 14.) This figure answers correctly, as to its scale, to the preparation from which it was drawn ; and shows how considerably the womb was enlarged at the time of the woman's death; upon looking at the specimen, after closing the incision, we might be easily misled, so far as to think such a case would, in life, be readily amenable to treatment like Fig. 12 ; but on cutting it open by an incision from the fundus down to the cavity and canal, and to the os, it is seen that the interior is irremediably diseased, the substance of the walls being converted into OF THE NECK OF THE UTERUS. 73 a sort of pennicillated structure, of which the ends of the pencils exhibit small tubercular elevations all along the inner wall. A casual examination by touching, or even a careful metroscopy could not be expected to clear up such a diagnosis as this one; and all attempts to restore a healthful crasis and form to such degenerated tissues, by leeches, by escharotics, either on the outside of the neck or within the canal, must have failed. We know nothing farther of this case — it having come into our possession by the politeness of a stranger. Nevertheless, it is a specimen most useful in the study and minute research so desirable, as to these recondite sexual maladies. We have recently witnessed the death of a fine woman, who perished under this precise form of disorder immensely aggravated. Changes taking place in parts of the texture of the inner wall of the cervix must be as various as accident could make them. Such a pennicillated degeneration as the above, being one form, it is not difficult to con- ceive of other modifications as producing either fibrous or cellular polypus, or the more unmanageable forms of Hosmatomatous degeneration, of which we have met with not a few examples in our practice, and we shall now introduce into our Essay the figure (Plate 15) repre- senting a case which was for a considerable length of time under treatment without any useful influence being produced therefrom. The womb was carefully examined, with a view to determine its dimensions and probable weight. It was 74 ACUTE AND CHRONIC DISEASES not more than four inches in its longest diameter. The os was of an oval shape, and the edges or lip was much condensed — to such a degree, indeed, as to com- municate, by touching, the idea of scirrhous induration. Projecting very little beyond the plane of the orifice was a hsematomatous mass, that evidently sprung from the right side of the wall of the canalis cervicis by a broad origin. This bleeding tumor is well represented in the drawing, in which the chirurgical neck, fore- shortened, is seen to look like a bourrelet or ring pro- jecting in the vagina, which is opened. The hemorrhages, here, were on some occasions very threatening. There was little encouragement to be taken from the suggestion to remove the fungus by strangulation — a step forbidden, also, by the delicate state of the woman's general health. Without indulging idle hopes of effecting a cure, and with clear understanding that no promises to that effect were given, or any flattering hopes held out, the case was conducted for a few months under very unfavor- able circumstances, by means of nitrate cauterizations, destructive as to the ha3matorne, but antiphlogistic as to the cervical ring. They, perhaps, cannot be said to have done any good; unless, indeed, we might attribute to them the diminished frequency and force of the hemorrhages, and, perhaps, also some positive reduction of the fungus itself. Circumstances rendered it inexpedient to continue these attempts at amelioration, which were unattended with pain or any other sanitary inconvenience. The OF THE NECK OF TIIE UTERUS. 75 treatment was repeated about once in every seven days, from the date in May, 1852, until the close of autumn. Certainly no aggravation was noticeable up to the final period of these attempts; and the patient went away supposing herself to be somewhat improved in general health. She is since dead. As a general conclusion, a physician might venture, in such cases, to pronounce them incurable. Women often complain of irregular mensual returns, saying, that while the legitimate periods are duly and healthfully observed, they are, in addition, vexed with an occasional show after any considerable exertion. Women are apt to regard every sanguineous discharge from the genitalia as menstrual discharge. All those who recognize the truth that menstruation is one of the phenomena of ovulation, will at once sus- pect that such irregular markings must arise from some cause other than the physiological hypersemia of the ovulative act. And, in fact, it is mostly found, upon due inquiry, that the patient has the raspberry-colored inflammation of the cervix, already described ; or she has certain small vivaces, or bunches of red cellular and capillary tissue, which are either found peeping out at the plane level of a somewhat patulous os tineas, or jutting quite forth out of and beyond it, and attached by a delicate peduncle or footstalk. No one could expect to cure such a disorder as this by any sort of constitutional therapy, or by any vaginal injections; and it is not safe to leave them to their own tendencies, which would perhaps convert them into very 76 ACUTE AND CHRONIC DISEASES troublesome bleeding polypi — many of which are to be met with in a long professional course of observation. A specimen of this kind is seen in the annexed figure (Plate 16, Fig. 1). It represents the os uteri of a lady, who, without having much real indisposition, was never- theless excessively annoyed by circumstances like those we have now detailed; and who indulged apprehensions of some disastrous term to them. Examine the draw- ing: it so very accurately exhibits the appearance both of the neck of the womb, and the little tumor or ex- crescence, that it scarcely requires description. Never- theless, it is proper to call attention to the hyperemia, or inflammatory turgescence of the os tineas, and to suggest the notion that this redness and appearance of phlogosis probably extended some distance upwards within the canalis cervicis, thus maintaining a molimen hemorrhagicum, which, upon the slightest provocation, might cause a moderate gush, or marking of blood to appear, as particularly after a sexual union. In a great many cases like this, it is customary with the author carefully to seize the excrescence, or nascent polypus, with the dressing forceps, and so twist it off at the base, if practicable, and, immediately afterwards, to apply the nitrate pencil strongly to that base, or, on some occasions, to use a camel-hair brush dipped in acid nitrate of mercury, which answers well and is followed by no inconvenience, particularly if a small velvet sponge, thoroughly imbibed with soap-suds, is immedi- ately afterwards pressed against the surfaces. The soap OF THE NECK OF THE UTERUS. 77 decomposes the excess of acid, and prevents the spread- ing of the escharotic beyond the place of contact. One need not expect that the avulsion of these little polypi shall certainly effect the cure — for they are very likely to be reproduced; probably, because only the most outward parts have been removed. When pro- perly removed, even down to the very source, it is un- likely to reappear; but a second and a third attempt should be made, if necessary. The case above illustrat- ed was cured in 1851, and to all appearance remained so — the lady having no annoyance of the kind until, in the winter of 1852-3, she began again to perceive signs of its return, and now she has an excrescence like the one in the drawing, at the left angle of the os. We have other drawings, exhibiting cases in which man3 T such little excrescences were observed to jut forth of the opened os, looking not unlike so many very ripe red currants. We have treated them as above proposed, and with satisfactory results. It seems needless to in- troduce many of them here. Nevertheless, we have in- troduced the figure (Plate 17), showing the appearance of the excrescences protruding like ripe currants from the os tincce, as mentioned on the opposite page. In this case, under treatment in the spring of 1853, there was hypertrophy of the womb to such degree, as to allow the fundus to be felt quite two and a half inches higher than the plane of the superior strait. In continuation of these clinical details, we now re- mark, that the lady from whom the drawing (Plate 16, Fig. 2) was taken, complained of monorrhagia gradually 78 ACUTE AND CHRONIC DISEASES increasing in violence, and settling at length into an incessant drainage, under which she became excessively weakened and pallid. She had borne no child for some sixteen years, and, like a majority of women similarly affected, was confident that her trouble arose from what they call change of life. She refused, during some eighteen months, to submit to a physical diagnosis, and became, at length, so dreadfully affected with hydrsemia, that her life seemed to be in great danger. She was repeatedly informed that the word change of life, as used in general, conveys no distinct idea, and that her issue of blood must arise from some organic fault. At length the blood, from continual waste of the solid constituents of it, became so dilute, so hydremic, that she could not walk across the carpet without bringing on palpitation, nor ascend the stairs but with caution, and always with much difficulty. Seeing that she had no other hope of amendment, she submitted to an ex- amination, whereupon the small pedunculated vascular excrescence, or polypus, was discovered, as shown in Plate 16, Fig. 2. It was immediately twisted off. The hemorrhages never returned afterwards, and she has had good health these now many years. This example and statement suffice to fulfil our pur- pose in this relation, which is the reason why we detail no other similar instances — which w r e could do, drawling on the stores of our personal experience in practice. It is of the utmost importance in the practice of physic and surgery, to make absolutely correct diagnos- tications, since all our prognosis, as well as treatment, OF THE NECK OF THE UTERUS. 79 which is contained within the diagnosis, depends upon being right in the beginning. This opinion will be admitted to be just by all those who belong not to the empirical schools of our art, but, on the contrary, adhere to the rationalists in Medicine. There is a great liability, even among the most ex- perienced men, to be led into ludicrous or even fatal mistakes in the diagnostication of the so-called diseases of the cervix. A lady came to Philadelphia complaining of uterine disease, that had baffled her physicians at home, and applied for advice to an expert. Upon some considera- tion, the author was invited to attend in consultation, and dissented from the opinion that was entertained by the attendant. Patient had been affected with some form of violent intro-pelvic inflammation, which, we believe, had been regarded as metritis, by a misapprehension of its seat. After protracted and great suffering, and after several operations with the knife — the precise nature of which we do not know — she was observed to have the vagina so much diminished in length, that her relations of a marital nature became impossible. She came to Phila- delphia, as before mentioned. The canal of the vagina was about an inch in depth, and no more. At the bottom of this cul-de-sac was a firm substance, that was mistaken for the chirurgical neck, and the delicate aper- ture in it for the os uteri. To the touch, such a case presents the greatest simili- tude to the mammillary projection of the womb, and is, 80 ACUTE AND CHRONIC DISEASES therefore, a great stumbling-block in the way of diag- nosis. The medical gentleman, whom I met, insisted that it was the os uteri, and that adhesion of the vagina to the whole exterior vaginal cervix gave it the present appearance, as at a in the diagram on the next page. Dissenting from this opinion, we averred with equal confidence that the womb could not be touched, nor even approached, and that the so-called os was nothing more than one of the apertures in a long vaginal stric- ture, and that the womb itself was not at all implicated in the disorder, save in so far as it was imprisoned above this impracticable stricture, amounting nearly to atresia vaginae. See (b) in the diagram. Some months subsequent to these discussions, the lady returned to Philadelphia, and placed herself under the sole direction of the writer of this statement, and went away cured. On the next page we have given an outline drawing, or diagram, which shows how readily one might mistake the thickened bourrelet (a) for a vaginal cervix and os uteri; whereas, in truth, the os uteri is above, and in the free part of the vagina marked (b) . To look at the diagram, it is easy to perceive the truth as to such a case, while, in practice, the diagnos- tication had, and has deceived many an experienced and able physician. We have now under treatment a case precisely ana- logous, affecting a woman about fifty-five years of age, which was handed over to us by an eminent practi- tioner, who had treated it for some time under the con- OF THE NECK OF THE UTERUS. 81 viction that what he touched, as in the figure (at a), was the os tineas, in a state of cancerous induration. And it ought to be observed that, in all such instances Fig. 2. coming under our notice, we have found the part so very solid and scirrhous, as to lead to fears that it could not be amenable to any power of resolution. It is well known that some urethral strictures do become almost callous. When called to examine the state of the parts in this 6 82 ACUTE AND CHRONIC DISEASES case, we were, at first, startled to find such an appear- ance of malignant disease ; but a little reflection enabled us to doubt of the fact. This doubt was easily resolved by passing the probe point of Simpson's sound along and quite through the lengthy stricture, into the free and ample vaginal cavity above. That this was done was verified by an examination made through the walls of the rectum, in doing which the probe point, in the free cavity, was recognized, as well as the shaft of the sound lying in the stricture, and closely embraced by it. The same method of making this diagnosis was employed in the first case described in this connection; and it is one always to be resorted to and relied upon with im- plicit confidence. Having stated these cases, which are not affections of the cervix uteri, we hope to be absolved from any charge of transcending the limits assigned to us, inasmuch as we have deemed it proper to array all the means of differential diagnosis that might haply serve to prevent misapprehension in the cases we have felt charged to treat of, and shall now ask liberty to refer to a work entitled "Woman, her Diseases and Remedies," page 106, for the history of a case whose circumstances are forcibly recalled to memory by the above observations. Hitherto we have not, in this treatise, said anything in regard to the malignant degenerations of the texture, so often met with in inquiring into diseases of the neck of the uterus. To dilate upon all the forms of malignant chronic or acute diseases of the cervix would require a considerable OF THE NECK OF THE UTERUS. 83 volume, and it is not to be supposed that such a detail would fail to exhaust the patience of the reader. The figure (Plate 18), which we have in this connection pre- sented, is designed to illustrate one form, of chronic dis- ease of the neck of the womb, which, in the case at least from which the figure has been carefully designed, was found susceptible of a radical cure. The patient was a very robust and stout married woman, aged about 30 years, less or more. She had children. Complaining of frequent attacks of irregular menstrua, she appealed for advice to a physician, who, giving an unfavorable prognosis, so excited her fears and the anxiety of her family, that the author was invited to form an opinion on the case. The vagina contained a substance of the size and shape of the red mass which, in Plate 18, is seen spring- ing from the anterior aspect of the vaginal cervix. To the touch, it communicated the impression always pro- duced by touching the tissues in scirrhus or carcinoma uteri. It had the same resistance, and roughness or grater-like feel that belong to cancer of the womb or vagina. The gentlest touch caused it to bleed. It was not sensitive so as to be intolerant of pressure. The posterior aspect of the cervix gave, by the touch, the idea of normal tissue; and this was likewise the case as to both the lips of the os tineas ; and, indeed, all the accessible parts of the womb seemed to be perfectly sound and healthy, save only where the peduncle, or root of this malignant mass, arose from the anterior aspect of the neck. The vagina was everywhere quite 84 ACUTE AND CHRONIC DISEASES healthy. An inspection of the figure must produce the same impressions as were excited in the author's mind by the physical diagnosis. It would, in such a case, evidently be useless to apply any dressings to the surface of the tumor, which must be supposed to be all of one quality and vital temper, from the base to the apex. It would be a mere waste of time, therefore, to act upon the surface of it only. But if the diseased mass, in fact, proceeded from the base alone, on which it rested and depended for its ex- istence, then one might hope that, in eradicating the very base itself, would be found a sure remedy for an otherwise fatal extension of the degeneration. It was, accordingly, proposed that the mass should be removed, either with a uvula scissors, or by means of a ligature. The ligature being preferred, was applied, and the mass came away after a few days. It was also proposed that, as soon as the tumor should come away, the base or root should be destroyed by actual cautery, or by acid nitrate of mercury. The latter was adopted. Every vestige of diseased structure was thus removed, and the lady has now, for three years, enjoyed good health ; having experienced very little in- convenience during the whole process of cure. The question naturally here arises, whether this was a malignant tumor or no. We are aware that some persons will be likely to regard its curability as evidence of its non-malignant nature ; but, as for us, we consider that such a mass, being left to work out its own com- plete development, could not fail, in the progress of it, 1 OF THE NECK OF THE UTERUS. 85 to involve in destruction larger and still larger portions of the uterine tissue, and at last bring the life of the patient to a premature close. If the tumor was not malignant, it would become so if left uncured. It would have been, perhaps, hopeless to attempt the cure, had the examination not given the most flattering assurances that the diseased mass sprung from a rather superficial portion of the cervix, as was ascertained by the touch. We doubt not that, in numerous instances of parts wholly changed like this, cures have been and will be effected by removing all changed texture — ex- posing sound surfaces, which, being filled by healthy granulation, restore completely, or almost completely, both form and function to the before diseased parts. We shall next beg leave to call attention to a form of diseased cervix, of which, during a very long and co- pious experience in practice, we have met with but one solitary example. And even this is rendered less use- ful, perhaps, by coincident circumstances of the patient, that serve to lessen the value of the case as furnishing experimental results of the treatment. The lady was near fifty years of age, had borne several children, but none since seven or eight years. She was in an ad- vanced stage of pulmonary tuberculosis, and evidently destined, at an early day, to die with pulmonary con- sumption. Certain symptoms, proceeding from intro-pelvic dis- turbance, and causing great distress, led to the opinion that the whole case was aggravated by some form of uterine irritation ; and as she was anxious to be re- 86 ACUTE AND CHRONIC DISEASES lieved, and willing to undergo an examination, it was found, on making one by the touch, that the vaginal neck and os were both enlarged and painful. The mouth of the womb was much more patulous than it ought to be, and a lump was perceived upon the anterior aspect of the chirurgical neck. On exposing the point by means of a Recamier tube, there was seen a bright elastic tumor of a translucent appearance, which is represented in Plate 19, Fig. 2. The lady, even in her low state of health, was con- vinced that she was pregnant ; but the womb could not be felt through the hypogastric integuments. Whence it was inferred that the organ was of the form and dimensions given in Plate 19, Fig. 1. Professor Mutter opened this hygroma with a sharp- pointed, narrow bistoury, and there issued from it a few drops of colloid fluid, but as transparent as albumen ovi; after which came away a few drops of blood, whereupon the tumor, or hygroma, collapsed, and the lady, whose consumption made continual progress, had little or no farther trouble from this special cause ; a few touches of the pencil of argent, nitrat. having dissipated the inflammation and engorgement of the womb. A few months later, she died, exhausted with hectic — the lungs being utterly disorganized by softened tuber- cles and numerous vomicse. A post-mortem examination being allowed, it was found that the hygroma had not filled again, but left a bluish spot or blain. The os was still a good deal open, but the neck was little enlarged. Plate 19, Fig. 1, shows OF THE NECK OF THE UTERUS. 87 a profile view of this uterus, which is deemed well worthy of observation, particularly because the fundus was converted into a tumor, which is seen like a sub- rotund swelling at the left hand end of the figure, and somewhat separated from the general mass of the uterus by the sort of strangulation or groove seen in the pic- ture. This was a firm fibrous product, developed out of the substance of the fundus itself, which underwent this fibrous conversion, while every other part of the organ retained the equable ratios of its several elementary or constituent tissues. We observed that we deemed this case interesting, and it is so, chiefly in this, that it would be likely to give rise to a false diagnosis, and that on the following accounts : — Leaving out of consideration the tuberculosis, which, it was manifest, must, at no distant day, destroy the patient, and judging only from the results of the pelvic examination, and the inquiries made at the surpubal region, one would be led to pronounce a flattering prog- nosis, since one would scarcely doubt of his ability to cure all the evident disorders of this womb. Yet, no one could examine the necroscopic specimen without at once perceiving that it would be impossible to cure such a womb as this. The apparent fundus is not the fundus, in fact, but is a fibrous tumor, into which parts of the true fundus have been converted. It is inaccessible to any surgical means, and is wholly disobedient or indiffer- ent to every therapeutical force. As well might we administer medicines to convert a femur into a tibia, 88 ACUTE AND CHRONIC DISEASES and vice versa, as to give them ip convert a tumor into a natural tissue again. The attempt is ever a ridicu- lous one, evincing a complete misunderstanding of the laws of life, as well as of the scope of the medical art. A swelling may be cured again ; but a tumor is a new product, and as much an independent organism as a lung, an eye, or a muscle. It has, however, no generical destiny ; and, therefore, can obey no therapeutical law. Before bringing this paper to a close, we shall present a few remarks on the subject of displacement of the neck of the womb ; and we begin by referring to our Plate 3, to show the due relations, as to distance, of the os tincce from the walls of the pelvis. The ligamenta utero-sacralia, so called by the anato- mists, appear to us to be rather deserving the denomina- tion ligamenta vagino-sacralia ; for they are in reality duplicatures of peritoneum running backwards, one on each side of the pelvis, from the posterior or upper extremity of the vagina to the sacrum. It seems to us that their office is to keep the end of the vagina at a certain place, near enough to the lower part of the sa- crum ; and certain it is that, as long as they preserve their due firmness or tension, the upper end of the vagina cannot drop down from near the sacrum to near the arch of the pubis. A line drawn from the lower part of the sacrum, say near its fourth segment, to the top of the arch, is at least four and a half inches. When we find the os tincaB jutting outside of the arch, we know that the vagina has fallen at least three and a half inches, and of course that the ligamenta utero-sacra- OF THE NECK OF THE UTERUS. 89 lia are stretched or elongated to that amount. But when, on making such an examination, we thrust or carry the cervix uteri backwards and upwards to its true place, then the ligamenta utero-sacralia become again as short as they ought to be; and if they would remain permanently so, we should cure the patient merely by thus thrusting the uterus up to its true place. But, un- fortunately, when we take away the support, it falls down again ; because the utero-sacral folds, and all the serous and cellular or areolar relations of the vagina are weak and relaxed, and cannot hold it up. Now, if this be a just representation of the facts, no one can deny that prolapsus uteri is a disorder or weak- ness of the vagina and its ligaments, and that to cure the prolapsus we must cure the vagina first ; it being evident that, with a vagina of three and a half inches in length, the womb cannot quit its place in the pelvis. The womb, as we have already said, is two and a quarter inches in length, and the longest antero-pos- terior plane within the pelvis may be assumed to be four inches and a half. Hence, it is clear that, if the womb be thrown over backwards, so as to let its fundus fall into the rectovaginal cul-de-sac of peritoneum, called the Douglass cul-de-sac, it is inevitable for the cervix uteri to come forward ; for the uterus cannot well turn over without a see-saw movement. If, therefore, the womb preserve its rigidity, and it be retroverted, the os tineas must come near to the symphysis pubis. This would be the case in all instances of retroversion with- out flexion of the longitudinal axis of the uterus. We 90 ACUTE AND CHRONIC DISEASES have met, in practice, with many instances of this kind, and in more than one remarkable case have found the fundus fastened down in its unnatural bed in the pelvis, by means of strong adhesions, which it was necessary to divide with the scalpel before we could reduce the uterus into its proper position again. One was a case of retroversion, with hypertrophy of the womb coinciding with fatal Fallopian pregnancy. The organ stretched across the pelvis, from the sacrum to the pubis, fully four and a half inches. The specimen is in our collec- tion. Another was a case of uterine pregnancy. But, while it is true that the uterus, being of a rigid and firm consistence, does not always bend in retrover- sion, it is very common to meet with specimens in which the organ is bent at a right angle, or even more than that. Retroversion, with an unbent womb, is a Fig. 3. mere accident or chirurgical disorder ; whereas retrover- sion, with a bent or angulated uterus, is a case in which the womb has itself become diseased. It is a case in OF THE NECK OF THE UTERUS. 91 which, by the nutrition of one segment or half of the womb, it has grown smaller or larger than the other symmetrical half or segment ; for, it is clear, if both the anterior and posterior halves should grow or be de- veloped pari passu, the organ could be only straight, and could be by no means crooked or bent, as in the above diagram. The quantity of the convex must greatly exceed the quantity of the concave half; otherwise, the womb could not be bent, but must remain straight or fusiform. In treating these retroversions, therefore, we must expect to meet with greater difficulty and delay in the case, if we have an angulated organ to rectify, as well as a case of retroversion. We do not mean to say that the methods are different, since there is but one good method for all of them, and that is a treatment by the pessarium of a proper form. And here we may beg leave to notice what we regard as a great oversight on the part of practitioners, in re- gard to one of the chiefest sources of embarrassment and ultimate disappointment of the cure. The circum- stance here alluded to is this. In retroversions of some considerable duration, the anterior column a of the va- gina has become shortened, and, in consequence of its being without any antagonistic or opposing force, allowed so to coacervate its material as to be indisposed afterwards to remain in the state of extension natural to it. We believe that all living soft parts have an inde- feasible tendency to consolidation, when not prevented 92 ACUTE AND CHRONIC DISEASES by an antagonizing power. This depends, indeed, on what Bichat announces as the contractility par defaut d extension. If the os uteri should be brought close to the symphysis pubis, and kept there for some months or years, it is clear that if any one should cause it to remove backwards again to its place three and a half inches away from the crown of the arch, and then let it go, it would leap back again to the vicinity of the pubis, being drawn thither by the anterior column of the vagina, which soon contracts again like a bit of stretched caoutchouc. Now, this is the circumstance which we complained of as being too much overlooked by our physicians in their intentions as to a cure. They are well enough aware that when the womb is overset, or retroverted, it is useless to reposit it, and then abandon it to itself, since it always falls over again with the first motion, or effort to stoop, or to cough, &c. They have used pessaries of every possible shape, and they have been much annoyed to find their patients worse instead of being better for their use. An immense use has been made of the globe-pessary; and certainly, in a simple prolapsus uteri, it answers admirably. But it does not answer well for the cases of retroversion; because the morbidly condensed and elastic anterior columna of the vagina, slowly contracting in order to recover a state of rest, pulls the os uteri for- wards over and above the convex upper surface of the ball, and draws it again close up to the symphysis, the fundus meanwhile sinking down backwards into the peritoneal cul-de-sac between the rectum and the vagina. OF THE NECK OF THE UTERUS. 93 In this case, the woman is greatly annoyed, having both a pessary and a retroversion to contend with. Many years ago, the author was in attendance on an aged woman, who had long suffered from prolapsus uteri. She had been taught, by a nurse, to construct a pessary, by making a whalebone ring, some three inches in diameter. This ring being wrapped or served with bobbin, was dipped in melted wax, until a sufficient coating of wax was given. In this way she made an elastic annular pessary, by means of which she was enabled to pass through many years of an advanced age, without any inconvenience from a procidentia which always threatened to return upon the removal of the support. The globe-pessary of Dr. Physick, and the concavo- convex disk, or Dewees's pessary, have been much em- ployed in Philadelphia, and throughout the United States generally, as might be expected from the eminent position and repute of both those gentlemen. The globe of Dr. Physick is liable to the objection above stated, as a remedy for retroversion ; and Dewees's disk is equally obnoxious to criticism, as being liable to injure the os uteri, which rests nearly vertically upon the metallic surface. Of course, the same objections lie against all the glass-pessaries, of which many thousands have been on sale in the drug establishments of our people. Indeed, they are at last becoming justly dis- credited. Seeing the difficulties that surround this subject, and acting on the experience of the aged lady already men- 94 ACUTE AND CHRONIC DISEASES tioned, the author constructed pessaries with watch- spring, as follows : — Take a piece of watch-spring of the proper length. That is to say, if a pessary of three inches diameter is required, take a lamina of watch-spring nine inches and three-sixteenths in length. Bend it into a circle, and rivet or solder it, to make an annul us three inches in diameter. Serve it all round with bobbin, or large twine, and then dip it again and again in melted virgin wax, so as to infiltrate the threads completely. Polish the waxen surface with the hands. This ring, which is Fig. 4. as elastic as watch-spring, can be compressed betwixt the thumb and fingers, so as to be converted from the OF THE NECK OF THE UTERUS, 95 shape of this figure (4) to that of Fig. 5, and then intro- duced into the vagina without giving the woman any pain. As soon as it has taken its place, it expands again, and recovers its original form. Previous to introducing the annulus, the womb should be reposited, either by the hand alone or by Professor Simpson's womb-sound ; and, that being done, the annulus acts in the manner illustrated by Plate 20, in which a silver ring, gilt, is made use of. Fig;. 5. Let it be observed that the distance from the pubis to the sacrum, in this plane, is at least four inches and a half, and that the annulus is three inches in diameter. 96 ACUTE AND CHRONIC DISEASES Now, if the ring is introduced in such a manner as to cause the sacral segment of it to pass behind the cervix, and rest in the cul-de-sac behind, formed by the poste- rior columna of the vagina, while the pubal or anterior segment rests on the symphysis pubis, it is impossi- ble that the cervix uteri should again come forward to the symphysis, or that the retroversion can occur again while the annulus is left in situ to prevent it. Indeed, the vagina is now full three inches in length, and not even prolapsus uteri can vex the patient ; for prolapsus is shortening of the vagina, and nothing more and nothing less. Such an annular pessary as this, left in situ for a few months, must effectually overcome the contraction par defaut d' extension of the anterior vaginal column ; and by allowing the ligamenta utero-sacralia to be at long rest, they, by coacervation of their substance, will re- cover their normal density or tone ; and so, the ring being at last taken away, the woman is found to be cured ; for the ligam. utero-sacralia are now condensed again, and the anterior columna vaginalis has regained its ductility. The method of constructing annular pessaries of watch-spring, as above set forth, was detailed at a meet- ing of the College of Physicians of Philadelphia, by the reporter. At a subsequent meeting of that College, one of the Fellows thereof, Dr. Charles Evans, reported an im- provement, consisting in coating the watch-spring- served annules with gutta percha dissolved in chloro- OF THE NECK OF THE UTERUS. 97 form ; and this fortunate idea has rendered the instru- ment so perfect, that we may suppose it to be all that could be wished for as an apparatus for the purpose of treating retroversions. Reporter has long used annules made of absolutely pure silver cylinders, bent into a circle and gilt with fire gilding. Such an instrument is excellent, and is so pliable that it may be crushed into an elliptical form before its introduction, and then, by a little dexterity, opened again into the circular form while lying within the vagina. This is perhaps the most perfect of these instruments, yet difficult to use and to obtain. A reference to Plate 20 shows that, if the posterior segment of such an annulus is lodged within the cul-de- sac of the vagina that is found behind the neck of the womb, while the anterior segment reposes upon the tissues just above and behind the crown of the pubal arch, it is absolutely impossible for the retroversion to take place ; and it is to be believed that, in a space of time, greater or less, according to a variety of circum- stances, all the tissues concerned in keeping the uterus in its place will recover their tone, by virtue of the phy- siological force called by Bichat contractilite par defaut $ extension. It could not be otherwise. As to the ex- ternal apparatus called utero-abdominal supporters, which we have the mortification to see prescribed and applauded by physicians and surgeons, even eminent persons in our class, we can but express again our con- viction of their utter uselessness, as well as the liability 7 98 ACUTE AND CHRONIC DISEASES of those who use them to aggravation of all the evils for which they are the pretended remedies. We have here placed a drawing (Plate 21), taken from the museum of Jefferson Medical College, at Phila- delphia, which represents one of the specimens there of polypus of the womb ; and we have felt constrained to present some remarks upon cases of this kind, inasmuch as they greatly interest the cervix of the uterus, whose acute and chronic diseases we are commanded to de- scribe. And herein we do not feel called upon to go into a full account of the various uterine polypi. Let it suffice to say that they consist of tumors, hard or soft, which rise up from the surface, whether exterior or interior, of the child-bearing organ : many of them, however, being developed in the very substance of the organ, and invading greater or lesser portions of its structure. These growing polypi depend upon non-equable de- velopment of certain of the elementary tissues of the womb, which, being produced out of all normal rate, may attain a great magnitude or mass. They vary from a few grains in weight, like the currant-shaped ex- crescence in Plate 16, Fig. 1, or the bunches in Plate 16, Fig. 2, or the more considerable tumor projecting from the os, in Plate 21. We possess specimens of the size of an ostrich egg, and one that was at least six inches in longitudinal by five in the conjugate diameter. We were present at the examination of a specimen, which was, at the time, weighed by the late Professor Wm. E. Horner, and found, with the womb which contained it, OF THE NECK OF THE UTERUS. 99 to weigh thirty-two pounds. The degenerated develop- ment-force, by means of which a fibrous polypus rises up on the surface of the womb, or within its substance, may, in some cases, extend so far throughout the whole limits of the uterus as to apparently convert the whole substance of it into the material or nature of polypus. We possess a specimen, in which it would be difficult to discriminate between the character of the large mass, into which the whole womb has become converted, and the substance of the large polypi just now mentioned as in our possession. But lest we should be tempted to carry this investiga- tion far beyond the limits proper for this paper, we shall confine ourselves to remarks upon the interior polypus, or polypus of the cavity of the womb. A tumor of this sort, which, at the commencement, might be supposed to be no bigger than a split pea, growing, by constant nutrition of its mass, soon comes to distend the cavity which it occupies, and that cavity must expand upon the same principles as those which regulate the physiological hypertrophization or evolu- tion of the womb in true pregnancy. If the polypus should take its origin within the true cavity of the uterus, the fundus and corpus uteri would, of course, first expand for the accommodation of the growing mass, just as happens in the early stages of a gestation. Under these circumstances, the form and size of the neck of the womb do not undergo any change, and an examination per vaginam would not enable a physician 100 ACUTE AND CHRONIC DISEASES to pronounce with assurance that any change whatever had taken place in the form and volume of the organ. The term expansion does not here imply merely a stretching of the walls — as when a bladder is blown, but it means a regular physiological hypertrophy, or growth. Now, when the womb grows, it must grow generically, and will, in such case, preserve its generical character as to form ; for the idea of genus and species cannot but include ideas of both form and substance, of superficies and solid contents; when the womb, or parts of it dege- nerate, then the form goes in the most convenient direc- tion, or qua data porta. A great uncertainty as to the existence or non-exist- ence of pregnancy ever attends the vaginal examination in the early stages; but in proportion as a polypus or an ovum becomes larger, so must the cervical por- tion of the womb grow shorter, until, at last, the cylin- droidal neck acquires the shape of a cone, or rather a conoidal form ; for a polypus, though it can grow indefi- nitely, and come to be of an enormous size at last, must ever mould itself upon the internal walls of the womb. The polypus, therefore, cannot so alter the shape of the womb as to give it a figure other than such as naturally belongs to it, and characterizes it whether gravid or not gravid. Sooner or later, in any case of polypus uteri, it may be expected that the lower segment of the tumor shall appear at the os uteri, and gradually dilating it more and more, open it at last so widely that the contractility OF THE NECK OF THE UTERUS. 101 of the fundus and body shall be able to thrust the tumor out into the vagina. In the figure (Plate 21) it is seen that the polypus begins to show itself very plainly at the opening mouth of the womb. But, with the cone of the cervix, and the circle of the os so thick and strong as here shown, it could not be that the polypus shall very soon be ex- pelled from the uterine cavity. It might be a question whether the diagnosis of such a tumor is to be absolutely relied upon, seeing that it so closely resembles the case of haaniatoma or bleeding fungus, represented at Plate 15 of this report. Yet it is not difficult, either with the index finger alone or with a womb-sound, to ascertain that the fungus at Plate 15 is a hematoma springing directly from the inner wall of the canalis cervicis, while the other tumor (Plate 21) is a real uterine polypus rising from a portion of the wall of the true cavity. I may repeat that the shape assumed by the womb in a natural pregnancy is well known ; and that in all cases where the womb contains a true polypus of the cavity, it in like manner preserves its natural form. But, if a fibrous or other degeneration within its texture takes place in the very substance or walls of the womb, making one or many fibrous tumors, the womb loses its normal form, and becomes lumpy or botryoidal. The examination of such cases should, hence, always be so conducted as to lead to a knowledge of the form actually possessed by the enlarged organ. If that form be normal, or generical, then we infer that the enlarge- 102 ACUTE AND CHRONIC DISEASES ment is occasioned by the presence of something moulded into shape by the womb itself, and that it is an ovum or a polypus. If, on the other hand, the generical form is not preserved, we may infer the exist- ence of some morbid growth outside of the cavity, but within the very substance or walls of the womb. The uterus is destined, normally, to discharge a quantity of blood from its cavity with every periodical ovulation, and the custom of women is one so regularly observed, that it gives to the mind a tendency to regard every discharge of blood from the organ as a menstrual discharge. Hence, when women find themselves bleed- ing too often, too copiously, or in a way too greatly pro- longed, it is their habit to consider the deviation as a fault of their courses. They do not, in general, consider that blood may issue from such a sanguine organ, with- out the discharge having any relation whatever to their mensual act ; and they usually speak of all such preflu- via as disorders of the menstruation. A medical man, on the contrary, ought to possess an ideal standard, by which to compare every such case, and he must at once perceive that such a state cannot possibly be a men- sual state, but must be related to some other quality and faculty than those of ovulation and menstruation. Enough has been already said in this work to show that morbid changes in the corpus mucosum of the womb may serve to explain the frequent reappearance of sanguine discharges from the genitalia. Such dis- charges as these, however, are not for the most part copious and wasting. It is true, however, that such OF THE NECK OF THE UTERUS. 103 discharges are most apt to coincide with the hyperaemia of the ovulation, or to have relation to some mental or physical shock, or to the sexual insult, &c. &c. In cases like that portrayed at Plate 21, the proflu- vium of blood is likely to be independent of any perio- dical ovulation, and, indeed, in some instances, is never wholly absent, while the subject of it is liable to sudden enormous effusions of blood, generally greatest at the mensual periods. "We have elsewhere related a case, in which the woman was never, during six years and a half, without bloody issue from the genitalia ; an issue which arose from a polypus passed into the vagina. So many striking instances of this either frequent or con- stant hemorrhage have occurred to us in practice, that we spontaneously, as it were, adopt it as prima facie evidence of the presence of a uterine polypus, when we discover such frequent, or copious, or constant sanguine evacuations. A polypus, like that in Plate 21, whose lower seg- ment peeps out from the opening os, and whose sides are compressed or strictured by the firm walls of the cervix uteri, could hardly do otherwise than bleed more or less day and night, since the stricturing cervix must necessarily keep up a molimen hgemorrhagicum in the uncovered and uncompressed superficies of the tumor. It is not always, however, the polypus alone that has begun to project beyond the stricturing circle of the os that bleeds. Many wombs are kept in a state of hy- peraemia and hemorrhagica! fulness by the presence and 104 ACUTE AND CHRONIC DISEASES pressure of the polypus, and such cases are marked by the most violent floodings. Now, when we come to inquire diagnostically into such cases, and find, upon touching, that the os tincse is unmodified, and the cylin- drical neck unchanged, all that we can do is to infer, for we cannot know, that the hemorrhages are caused by a polypus in the cavity, whose existence, however, we can only conjecture or infer ; and especially where the poly- pus is still so small as not greatly to magnify the womb and make its increase perceptible, to the touch, in the surpubal region. There can scarcely be found, in the whole range of medical duties, a more difficult case of diagnosis than this. Time alone can solve the problem; and then only by protruding the mass into the cervix, or out into the vagina, whereupon all doubt is at an end. In numerous instances, our inferential diagnosis has been verified by immediate examination, or by after events. Yet we have met with samples of such hemor- rhage impressing us with a sort of inward conviction that they could only arise from polypus, a conviction which proved to be a baseless hypothesis, destitute of any foundation of truth. We have dwelt thus long on this subject, chiefly out of an anxious desire to put our friends and brethren on guard against making too hurried a diagnosis, and also as a preface to the drawing, Plate 22. The annexed figure, Plate 22, was drawn from the specimen at the time a jpost-mortem examination was OF THE NECK OF THE UTERUS. 105 made to ascertain the cause of a fatal uterine hemor- rhage. The woman, several years married, had borne no children. During two or three years, she had been under the medical care of the author, who, observing her to be occasionally seized with frightful uterine hemorrhages that left her always excessively hydrsemi- cal, could not avoid the conclusion that a small polypus concealed within the cavity of the womb, but undiscern- ible by any physical examination, would at some future time be thrust out into the vagina, so as to allow of its removal. Repeated careful examination left the same impression upon the mind. Meanwhile, when the floodings should be too wast- ing, she was advised to resort to rest, to haemostatics, and, above all, to the tampon for the vagina. Having removed her residence to a greater distance, she took counsel of another physician, and for more than a year occasionally suffered from attacks of very alarming floodings. Upon the last of these occasions, the writer was called in consultation with the attending physician, and, hastening to the rendezvous, found she had expired some four or five minutes before he arrived. It was with him and the attending physician anxiously desired, that the question of the existence, or non-ex- istence, of a polypus uteri should, in this case, be set- tled, and the figure (Plate 22) exhibits a very correct view of the cavity and walls of the womb. There was nothing upon the lining membrane that should throw any light upon the strange and most obstinate hemor- 106 ACUTE AND CHRONIC DISEASES rhages, unless, indeed, the magnitude of the cavity be so regarded; and its size is truly given, and may be compared with our figure, Plate 2, Fig. 2. But, upon the left ovary was a cystica! tumor, which is shown in the figure. Yet no one can assign such a cyst as a suf- ficient cause for those irregular and enormous uterine evacuations. I have, at this moment, under treatment the case of a maiden lady, about forty-three years of age, in whom the hemorrhages are immense and irregular — sometimes very alarming. In this instance, I can by no means detect any, the least, modification of the form, size, re- sistance, or natural place of the womb ; and, it is proba- ble that no man can say whether these distressing attacks arise from polypus, or no. It would be a most useful thing to possess some cer- tain methods by which to distinguish between habitual violent floodings without polypus uteri, and cases in which the polypus does exist, but cannot be come at. One can scarcely, in medical practice, be put to greater loss for some certainty in discrimination, than in such cases as these. The great length of this paper renders it necessary to bring it to a close. There is a considerable number of affections to which the cervix uteri is liable, which it would be easy to discuss ; and, in regard to the so-called malignant disorders of the part, it would be gratifying to us to describe and illustrate their various appear- ances, and suggest methods for their treatment. But we refrain from farther trespass on the time of the OF THE NECK OF THE UTERUS. 107 reader, to whom we offer the foregoing observations, in the hope that they may serve to remove some of the difficulties which we have noticed to exist in the path of the practitioner, not only in our own earlier days of observation, but now, and daily, in the numerous cases submitted under advice for our revision and counsel. If what has been presented is at once true and clear, we shall indulge the hope hereafter to have fewer calls from persons residing in distant States. In closing this essay, the Author takes the occasion to renew the expression of his sincere desire that the class of cases herein treated of may receive a greater share of attention from his brethren in the practice ; so that they may less frequently, than heretofore, be found to accumulate in the large cities and towns, or in the hands of specialists : he is convinced that, as such dis- orders require no greater amount of particular informa- tion or dexterity than other surgical and constitutional maladies, it is within the ability, and is the duty of the brethren generally, to conduct them safely and gently to a satisfactory cure. In our opinion, it would be much more creditable that such skill and discrimination should belong generally to the whole profession, than for one or two individuals in a district, or in a great metropolis, as London or Paris, to acquire a notoriety, which, to say the least of it, is scarcely enviable ; since, among the humiliating services that physicians and surgeons are by their vocation obliged to render to the distressed, none can be more revolting to the sensitive mind than these. 108 DISEASES OF THE NECK OF THE UTERUS. It might, perhaps with consoling truth, be added, that few professional ministrations turn aside with greater certainty and celerity the attacks of disease, or arrest the shafts they aim at the existence of our clients. INDEX. A. PAGE Abdominal supporters reprobated 97 Abrasion of mucous surface of os, case 55 Abrasion of mucous surface of os to be avoided in cauterizations 55 Albuminous leucorrhoea 35 Annular pessary of gilt silver 97 Acid nitrate for small polypi 77 Acid nitrate in bleeding tumor 84 Adjustment of metroscope 41 Argent, nitrat. in inflamed cervix 53 Antiphlogistic contacts with argent, nitrat 53 Adherent fundus in retroversion 90 Adhesion of fundus 90 Angulated uterus in retroversion 91 Antagonism of parts 92 Anterior columna vaginae in retroversion 91 Anatomical relations and place of womb 31 Argument for metroscopic diagnosis 48 B. Bayle's account of Ricamier's instrument 20 Bivalve speculum-uteri 40 Blood from the genitalia often mistaken for menstrua 102 Bleeding from polypus 103 Bleeding tumor or hsematoma of womb 73 Boivin's plates not useful 19 C. Caoutchouc bottles of Hervez 68 Case to show in what instance diagnosis is impossible 72 110 INDEX. PAGE Case of strictured vagina mistaken for diseased os 79 Case of hydrgemia from small bleeding polypus 78 Case of inflammation framboistc, with plate 43 Case of molluscum on cervix 50 Case of bleeding tumor in cervix 83 Case of hygroma on cervix > 85 Carcinomatous tumor of cervix cured 83 Component elements of womb 26 Corpus mucosum of cervix inflamed 46 Cauterization of cervix by Lallemand's port-caustic 71 Currant-like polypi of os, with plate 76, 77 Canal of cervix obstructed by albumen, cause of sterility 56 Canal of cervix, hcematoma in the 73 Complement of the forces in the reproductive organs 24 Contracted columna anterior renders retroversion less curable 92 Contro-stimulant power of the nitrate of silver 54 Cervix uteri, hypertrophy of the 67 Columna anterior vagina permanently contracted 91 Cervix, inflamed case of, with plate 57, 58 Cervical distinguished from vaginal leucorrhcea 34 Comparison of touching with metroscopy as diagnostic 21 Cephalalgia from irritation of womb 32 Cervix uteri, bleeding tumor removed from the 83 Chronic tympany from irritated womb 32 Competency of professional people in the cases 23 D. Diagnostics of sexual diseases deemed difficult 18 Diagnosis, its importance as means of success 37 Diagnosis, physical, being declined, the practice is empirical 22 Diagnosis by touching by some persons supposed to be always sufficient.. 21 Diagnosis of retroversion 66 Diagnosis of polypus uteri difficult in some cases 99 Diagnosis of hypertrophy of the womb 101 Diagnosis of stricture vaginae 79 Debility from leucorrhcea explained 38 Differential means of diagnosis 21 Dimensions of the womb 27 Dimensions of the gravid womb 27 Discrimination of vaginal and cervical leucorrhcea necessary 34, 36 Disturbing power of sexual disorders 25 Drawings and colored prints unsatisfactory in most cases 19 Duverney's glands, discharge from, mistaken for fluor albus 34 INDEX. Ill E. PAGE Elementary or constituent tissues of the womb 21 Empirical practice when physical diagnosis is disallowed 22 Epithelial surface of os rarely abraded 55 Equable development of womb or hypertrophy 28 Evans's (Dr. Charles) improved elastic annular pessary 96 Falling of the womb is relaxation of utero-sacral ligaments 88 Fatal monorrhagia without organic lesion, case of 104 Fastidiousness as to diagnosis 22 Flexion of womb, with figure 90 Fluor albus often depends on inflamed cervix 32, 33 Follicles of cervix, albuminous secretion from the 35 Framboisee inflammation, irregular show from 75 Frequency of retroversion 61 Fundus uteri, adhesion of 90 G. Generic and genetic forces, relations of the 26 Gluey fluor albus 38 Guessing at the case 22 Gutta percha ring-pessary of Evans 96 H. Hoematoma in cervix uteri 73 Hemorrhage from hsematoma uteri fatal 74 Hemorrhage from the womb, often mistaken for menstrua 75 Hemorrhage from the womb, fatal, with no organic lesion 104 Hooper's plates referred to 19 Hygroma on cervix uteri, with a plate 85 Hypertrophy of the womb, diagnosis of 101 Hypertrophy of the womb 27 Hypertrophy of the womb, physiological or pathological 27, 28, 29 Hydrsemia from sexual disorders 32 Hysteria, probably radiated from reproductive system 25 Hysterical state from inflamed cervix, case of 50 112 INDEX. I. PAGE Ideal of reproductive apparatus 26 Ideal model or standard specimen of uterus 29 Ideal of operations to be performed with escharotics 54 Inadequacy of touching for diagnosis 22 Inner wall of womb degenerated, not to be diagnosticated always 72 Indurating inflammation of cervix, obstinate case of. 57 Injections per vaginam for inflamed cervix, little relied on 37 Involution of womb as antithesis of evolution 29 Involutive force cures hypertrophy 29 J. Jus docendi, &c 23 K. Knowledge, not belief, demanded in diagnosis 49 L. Lallemand's porM&iustic 77 Leucorrhcea from affections of uterus alone 33 Ligamenta utero-sacralia 88 Ligation for tumor of cervix, case, with plate 83 M. Medical men alone to decide on necessity for metrdscopic diagnosis.... 24 Medical men of United States, competent and honest 23 Medical profession injured by specialization of practice 18 Menstrua depend alone on ovulation 75 Menstrua not always coincident with bleeding from organs 102 Menstrua, irregularity of as to quantity from inflamed cervix 75 Menstruation, profuse, often depends on currant-like excrescences of os 76 Menorrhagia, fatal case of 104 Metroscope of Recamier, his account of 20 Metroscope objected to by some as useless 21 Metroscope, various forms of 38 Metroscope, Recamier's, preferred by author 39 Molluscum of cervix uteri 50 INDEX. 113 PAGE Metroscopy, relative indelicacy of Touching and 21 Motives to write this essay 17 Muciparous apparatus of cervix 47 N. Nitrate of silver, antiphlogistic contacts with 53, Nitrate of silver, curative contacts with t 53 Nitrate of silver, destructive contacts with 53 Nitrate of silver, indifferent contacts with 53 Non-coincidence of menstruation and genital hemorrhages 75 Normal hypertrophy of the womb 27 0. Orifice of stricture in vagina mistaken for os uteri 79 Os uteri, its normal appearance 43 Os uteri, excessively patulous 75 Os uteri near pubis in retroversions 89 Ovulation is the direct cause of menstruation 75 Palpitation of heart from womb diseases 32 Pathology of retroversion 84 Pathology of hypertrophy 27, 28, 29 Pathology of raspberry-coloured inflammation 42, 55 Pessary, Evans's annular 93 Pessary, silver gilt, of author 97 Pessary, glass, objections to 93 Pessary, globe, fails to cure retroversion 92 Pessary, watch-spring, of author 94 Pessary, whalebone ring 93 Pathological hypertrophy 27, 29 Physiological hypertrophy of womb 27 Physical diagnosis of sexual disorders indispensable 38 Place of the womb in the pelvis, and its anatomical relations 31 Plate of the womb 29 Polypus with hemorrhage 103 Polypus of thirty-two pounds weight 98 114 INDEX. PAGE Polypus of the os causes drainage of blood, with anaemia 78 Practice in sexual maladies not a specialty 18 Prolapsus uteri 88 Pure silver to make annular pessary with 97 R. Rareness of ulcer of os uteri or cervix 24 Raspberry-colored cervix 42 Raspberry tinted inflammation of os, with plate 43 Recamier's (Professor) metroscope 19 Recamier's (Professor) Recherches sur le Cancer quoted 19 Recamier's (Professor) speculum uteri described, with plate 40 Reaction of reproductive organs on the animal economy 24 Reproductive force not an indifferent in woman's health 25 Reproductive force, when morbid, becomes a radiant of disturbance ... 28 Retroflexion of womb 62 Retroversion certainly curable by means of the annulus 96 Retroversion, old cases of, with condensed anterior columna 91 Retroversion, see-saw descent of womb in 89 Retroversion not easily treated with the globe 92 Retroversion, gilt annulus of author in 97 Retroversion with hypertrophy 63 Retroversion, its frequency 61 Resolvent or deobstruent power of arg. nitrat 53 S. Sanguine discharges of vagina mistaken for menstrua 102 Sexual diseases act on the constitution as hysteria 25 See-saw descent of womb 89 Shortening of anterior columna in retroversion, its effects 91 Silver, nitrate of, in diseases of cervix and os 43 Silver, nitrate of, ideal of purpose in using the 54 Simpson's sound, a case in which it passed 6j inches in utero 66 Speculum uteri, objections to, motives for 19-21 Speculum uteri, Recamier's 19 Speculum uteri, bivalve 40 Speculum uteri preferred by author, with plate 39 Spasm from sexual diseases 32 Specialty, objections to 107 INDEX. 115 PAGE Specialty injurious to medical profession 18 Standard or ideal uterus 26 Sterility by albuminous leucorrhoea 56 Stricture of vagina 79 Stricture of cervix 80 Swellings and tumors, difference between them 88 T. Tissues of the womb 26 Torpor of bowels from uterine irritations 32 Tympany from diseased os 86 Touching averred to supersede the metroscopic diagnosis 21 Touching for diagnosis 38 U. Ulcer of womb a rare disorder 55 Unequable development of womb constitutes a tumor 28 Uterine disorders as easily diagnosticated as other diseases 18 Uterine disorders should be treated by the family physician 18 Uterine polypus, remarks on, as in plate 98 Utero-sacral ligaments or folds of peritoneum 88 Utero-abdominal supporters, reprobation of 97 Uterus with hygroma and tumor on fundus, plate 86 Vagina restrained from falling by ligamenta utero sacralia 88 Vaginal stricture mistook for os uteri, figure 79 Vaginal leucorrhoea not albuminous 35 Vaginal leucorrhoea less important than uterine 33 Vaginal injections little to be relied on in inflamed cervix 37 Vagueness of opinion on sexual disorders 17 W. "VVatchspring annular pessary of author 94 Watery or cream-like fluor albus 34 Weight of womb, non-gravid and gravid 27 116 INDEX, PAGE Womb, ideal model or standard of, plate 29 Womb, normal, hypertrophy of 25, 101 Womb, pathological hypertrophy of the 27, 29 Womb, involutive power of the „• 28 Womb, flexion of, with figure 90 Womb, falling or prolapsus of , 88 Womb, how situated in pelvis 31 Womb, retroverted, with plate , 61 Womb-sound, Simpson's 101 THE END, Fni.l Eg. 2. Plate 2 WDreser.Dei tan s fith -"hiii w Rate. 3 i ■'ON A Frey, Del TSuiclairs lith,fhil A Fray Del. T. Siaclar Fkta Plate 6 tsi Del T Pkt Lair : — : —a Plate 8. Rl5 1 R.tf.2 "A'Braser '.Smdairs Irtt Mnla. . ' H Plate .' F.DreserDel. : Sinclair's i Iks 11 - 1Z A' _reser 5:-.::b:-s hth ?h£ Plat i H -•r Bed T Sinclair* hth ?hu«. :.2m.cLiiri lithJfcil ! - Flat* hi Eg. Z ' Siniiairs Jift Hnt»' late 18 na ■ j a - •: ft,5 I Fip. 2 "WDressi :ir. ?hH 3 kte 20 T. 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BLOXAM, Formerly First Assistant at the Royal College of Chemistry. HANDBOOK OF CHEMISTRY, Theoretical, Practical, and Technical, with a Recommendatory Preface by Dr. Hofmann. In one large octavo volume of 062 pages, with illustrations. {Just Issued.) It must be underwood that this is a work fitted for \ cessary, with such manipulatory details as rendered the earnest student, who resolves to pursue for him- j Faraday's ' Chemical Manipulations' so valuable at self a steady search into the chemical mysteries of the time of its publication. Beyond this, the im- creation. For such a student the ' Handbook' will portance of the work is increased by the introduc- prove an excellent guide, since he will find in it, tion of much of the technical chemistry of the manu- not merely the approved modes of analytical investi- I factory." — Dr. Hofmann' s Preface. g-ation, but most descriptions of the apparatus ne- j ASHWELL (SAMUEL), M. D., Obstetric Physician and Lecturer to Guv's Hospital, London A PRACTICAL TREATISE ON THE DISEASES PECULIAR TO WOMEN. Illustrated by Cases derived from Hospital and Private Practice. Third American, from the Third and revised London edition. In one octavo volume, of 528 pages. {Now Ready.) The most useful practical work on the subject in the English language. — Boston Med. and Surg. Journal. The most able, and certainly the most standard and practical, work on female diseases that we have yet seen. — Medico-Chirurgical Review. We commend it to our readers as the best, practi- tieul treatise on the subject which has yet appeared — London Lancet. The young practitioner will find it invaluable, while those who have had most experience will yet find something to learn, and much to commend, in a book which shows so much patient observation, practical skill, and sound sense. — British and Fo- reign Med. Review. With no work are we acquainted, in which the pleasant and the useful are more happily blended. 1 combines the greatest elegance of style with the most sound and valuable practical information. We feel justitied in recommending it. in unqualified terms, to our readers, as a book from which they can scarcely fail to derive both pleasure and im- provement. It is truly a model for medical compo- sitions. — Southern Med. and Surg. Journal. ARNOTT (NEILL), M. D. ELEMENTS OF PHYSICS; or Natural Philosophy, General %nd Medical. Written for universal use, in plain or non-technical language. A new edition, by Isaac Days, M. D. Complete in one octavo volume, of 484 pages, with about two hundred illustrations. TACTICAL TREATISE ON INFLAMMATION OF THE UTERUS, CERVIX AND APPENDAGES, and on its connection with Uterine Disease. Fourth BENNETT (HENRY), M. D. A PRj ITS CER American, from the third and revised London edition. In one neat octavo volume, of 430 pages, with wood-cuts. Just Issued.) This edition will be found materially improved over its predecessors, the author having carefully revised it, and made considerable additions, amounting to about seventy-live pages. . This edition has been carefully revised and altered, When, a few years back, the first edition of the and various additions have been made, which render present work was published, the subject was one al- ii more complete, and, if possible, more worthy of most entirely unknown to the obstetrical celebrities the high appreciation in which it is held by the \ of the day ; and even now we have reason to know medical profession throughout the world. A copy j that the bulk of the profession are not fully itlive to should be in the possession of every physician. — : the importance and frequency of the disease of which Charleston Med. Journal and Review. \ it takes cognizance. The present edition is so much We are firmly of opinion that in proportion as a enlarged, altered, and improved, that it can scarcely kuowledge of uterine diseases becomes more appre- he considered the same work.-Dr. Ranking* s 46- siuted, this work will be proportionality established strilct - as a text-book in the profession. — The Lancet. , BLANCHARD TJA7" . AND SCIENTIFIC PUBLICATIONS. BARTLETT (ELISHA), M . D. THE HISTORY, DIAGNOSIS, AND TREATMENT OF THE FEVERS OF THE UNITED STATES. Third edition, revised and improved. In one octavo volume, of six hundred pages, beautifully printed, and strongly bound. The masterly and elegant treatise, by Dr. Bartlett is invaluable to the American student and practi- tioner. — Dr. Hohnes's Report to the Nat. Med. Asso- ciation. We regard it, from the examination we have made of it, the best work on fevers extant in our language, and as such cordially recommend it to the medical public. — St. Louis Medical and Surgical Journal. Take it altogether, it is the most complete history of our fevers which has yet been published, and every practitioner should avail himself of its con- tents. — The Western Lancet. Of the value and importance of such a work, it is needless here to speak ; the profession of the United States owe much to the author for the very able volume which he has presented to them, and for the careful and judicious manner in which he has exe- cuted his task. No one volume with which we are acquainted contains so complete a history of our fevers as this. To Dr. Bartlett we owe our best thanks for the very able volume he has given us, as embodying certainly the most complete, methodical, and satisfactory account of our fevers anywhere to be met with. — The Charleston Med. Journal and Review. BUCKLER (T. H.), M. D., Formerly Physician to the Baltimore Almshouse Infirmary, &c. ON THE ETIOLOGY, PATHOLOGY, AND TREATMENT OF FIBRO- BRONCHITIS AND RHEUMATIC PNEUMONIA. In one8vo. volume, extra cloth, pp. 150. BOWMAN (JOHN E.), M.D. PRACTICAL HANDBOOK OF MEDICAL CHEMISTRY. Second Ame- rican, from the third and revised Engli>h Edition. In one neat volume, royal 12mo., with nu- merous illustrations, pp. 288. (Now Ready.) BY THE SAME AUTHOR. INTRODUCTION TO PRACTICAL CHEMISTRY, INCLUDING ANA- LYSIS. With numerous illustrations. In one neat volume, royal 12mo. pp. 350. BARLOW (GEORGE H.), M.D. A MANUAL OF THE PRACTICE OF MEDICINE. With Notes and Ad- ditions by the American Editor. In one octavo volume. (Now Ready.) The position of the author as physician to Guy's Hospital and other large public institutions, is a sufficient guarantee of the extent and value of the experience which is here systematically re- corded and condensed. His aim throughout has been to produce a practical work, on which the student can rely as a guide, and to which the practitioner can refer with confidence. The additions by the editor comprise chapters on Cerebro-spinal Meningitis, Cholera Infantum, and Yellow Fever, besides numerous notes wherever the diseases or practice of this country seemed to render them necessary or desirable. BEALE (LIONEL JOHN), M. R. C. S., &c. THE LAWS OF HEALTH IN RELATION TO MIND AND BODY. A Series of Letters from an old Practitioner to a Patient. In one volume, royal 12mo. pp.296. BLOOD AND URINE (MANUALS ON). BY JOHN WILLIAM GRIFFITH, G. OWEN REESE, AND ALFRED MARKWICK. One thick volume, royal 12mo., extra cloth, with plates, pp. 460. BRODIE (SIR BENJAMIN C), M. D., &.c. CLINICAL LECTURES ON SURGERY. 1 vol. 8vo., cloth. 350 pp. COLOMBAT DE L'ISERE. A TREATISE ON THE DISEASES OF FEMALES, and on the Special Hygiene of their Sex. Translated, with many Notes and Additions, by C. D. Meigs, M. D. Second edition, revised and improved. In one large volume, octavo, with numerous wood-cuts, pp. 720. The treatise of M. Colombat is a learned and la- borious commentary on these diseases, indicating very considerable research, great accuracy of judg- ment, and no inconsiderable personal experience. With the copious notes and additions of its experi- enced and very erudite translator and editor, Dr. Meigs, it presents, probably, one of the most com- plete and comprehensive works on the subject we possess. — American Med. Journal. CURLING (T. B.), F. R.S., Surgeon to the London Hospital, &c. A PRACTICAL TREATISE ON DISEASES OF THE TESTIS, SPERMA- TIC CORD, AND SCROTUM. Second American, from the second and enlarged English edi- tion. In one handsome octavo volume, with numerous illustrations. (At Press.) COPLAND (JAMES), M. D., F. R. S., &c. OF THE CAUSES, NATURE, AND TREATMENT OF PALSY AND APOPLEXY. In one volume, royal 12mo., extra cloth, pp. 326. f> BLANCHARD & LEA'S MEDICAL CARPENTER (WILLIAM B.), M. D., F. R. S., &.C., Examiner in Physiology and Comparative Anatomy in the University of London. PRINCIPLES OF HUMAN PHYSIOLOGY; with their chief applications to Psychology, Pathology, Therapeutics, Hygiene, and Forensic Medicine. A new American, from the last anil revised London edition. With nearly three hundred illustrations. Edited, with addi- tions, by Francis Gurney Smith, M. D., Professor of the Institutes of Medicine in the Pennsyl- vania Medical College, &c. In one very large and beautiful octavo volume, of about nine hundred large pages, handsomely printed and strongly bound in leather, with raised bands. (Now Ready.) The best text-book in the language on this ex- tensive subject. — London Med. Times. A complete cyclopaedia of this branch of science. — N. Y. Med. times. The most complete work on the science in our language.— Am. Med. Journal. The most complete exposition of physiology which any language can at present give.— Brit, and For. Med.-Chirurg. Review. We have thus adverted to some of the leading -'additions and alterations," which have been in- troduced by the author into this edition of his phy- siology. These will be found, however, very far to exceed the ordinary limits of a new edition, "the old materials having been incorporated with the new, rather than the new witli the old." It now certainly presents the most complete treatise on the subject within the reach of the American reader; nnd while, for availability as a text-book, we may perhaps regret its growth in bulk, we are sure that the student of physiology will feel the impossibility of presenting a thorough digest of the facts of the science within a more limited compass. — Medical Examiner. The greatest, the most reliable, and the best book on the subject which we know of in the English language. — Stethoscope. The standard of authority on physiological sub- jects. * * * In the present edition, to particularize the alterations and additions which have been made, would require a review of the whole work, since scarcely a subject has not been revised and altered, added to, or entirely remodelled to adapt it to the present state of the science. — Charleston Med. Journ. Any reader who desires a treatise on physiology may feel himself entirely safe in ordering this. — Western Med. and Surg. Journal. From this hasty and imperfect nllusion it will be seen by our readers that the alterations and addi- tions to this edition render it almost a new work — and we can assure our readers that it is one of the best summaries of the existing facts of physiological science within the reach of the English student and physician. — JV. Y. Journal of Medicine . The profession of this country, and perhaps also of Europe, have anxiously and for some lime awaited the announcement of tiiis newedition of Carpenter's The most complete work now extant in our Ian- , Human Physiology. His former editions have for euage — N. O. Med. Register. m; ' n >' years been almost the only text-book on Phy- * b I siology in all our medical schools, and its cneula- The changes are too numerous to admit of an ex- j tion among the profession has been unsurpassed by tended notice in this place. At every point where : any work in any department of medical science, the recent diligent labors of organic chemists and I it is quite unnecessary for us to speak of this micrographers have furnished interesting and v.ilu- ! work as its merits would justify. The mere an able facts, they have been appropriated, and no pains | nouncement of its appearance will afford the highest have been spared, in so incorporating and arranging ; pleasure to every student of Physiology, while its them that the work may constitute one harmonious I perusal will be of infinite service in advancing system. — Southern Med. and Surg. Journal. physiological science. — Ohio Med. and Surg. Journ. RY THE SAME AUTHOR. (Now Ready.) PRINCIPLES OF COMPARATIVE PHYSIOLOGY. New American, from the Fourth and Revised London edition. In one large and handsome octavo volume, with over three hundred beautiful illustrations, pp. 752. The delay which has existed in the appearance of this work has been caused by the very ihorotigh revision and remodelling which it has undergone at the hands of the author, and the large number of new illustrations which have been prepared for it. It will, therefore, be found almost a new wcrk, nnd fully up to the day in every department of the subject, rendering it a reliable text-book for all students engaged in this branch of science. Every effort has been made to render its typo- graphical linish and mechanical execution worthy of its exalted reputation, and creditable to the mechanical arts of this country. This book should not only be read but thoroughly sludied by every member of the profession. None are too wise or old, to be benefited thereby. But especially to the younger class would we cordially commend it as best fitted of any work in the English language to qualify them for the reception and coin- prehension of those truths which are daily being de- veloped in physiology. — Medical Counsellor. Without pretending to it, it is an Encyclopedia of the subject, accurate and complete in all respects — a truthful reflection of the advanced state at which the science has now arrived. — Dublin Quarterly Journal of Medical Science. A truly magnificent work — in itself a perfect phy- siological study. — Ranking's Abstract. This work stands without its fellow. It ia one few men in Europe could have undertaken ; it is one no man, we believe, could have brought to so suc- cessful an issue as Dr. Carpenter. It required for its production a physiologist at once deeply read in the labors of others capable of taking a general, critical, and unprejudiced view of those labors and of combining the varied, heterogeneous materials at his disposal, so as to form an harmonious whole. We feel that this abstract can give the reader a very imperfect idea of the fulness of this work, and no idea of its unity, of the admirable manner in which material has been brought, from the most various sources, to conduce to its completeness, of the lucid- ity of the reasoning it contains, or of the clearness of language in which the whole is clothed. Not the profession only, but the scientific world at large, must feel deeply indebted to Dr. Carpenler for this great work. It must, indeed, add hugely even to his high reputation. — Medical Times. BY the same author. (Preparing.) PRINCIPLES OF GENERAL PHYSIOLOGY, INCLUDING ORGANIC CHEMISTRY AND HISTOLOGY. With a General Sketch of the Vegetable and Animal Kingdom. In one large and very handsome octavo volume, with several hundred illustrations. The subject of general physiology having been omilted in the last edition of (he author's " Com- parative Physiology," he has undertaken to prepare a volume which shall present it more tho- roughly and fully than has yet been attempted, and which may be regarded as an introduction to his other works. AND SCIENTIFIC PUBLICATIONS. CARPENTER (WILLIAM B.), M. D., F. R. S., Examiner in Physiology and Comparative Anatomy in the University of London. ELEMENTS (OR MANUAL) OF PHYSIOLOGY, INCLUDING PHYSIO- LOGICAL ANATOMY. Second American, from a new and revised London edition. Withi one hundred and ninety illustrations. In one very handsome octavo volume, pp. 506. In publishing the first edition of this work, its title was altered from that of the London volume, by the substitution of the word " Elements" for that of " Manual," and with the author's sanction the title of " Elements" is still retained as being more expressive of the scope of the treatise. To say that it is the best manual of Physiology now before the public, would not do sufficient justice to the author. — Buffalo Medical Journal. In his former works it would seem that he had exhausted the subject of Physiology. In the present, he gives the essence, as it were, of the whole. — N. Y. Journal of Medicine. Those who have occasion for an elementary trea- tise on Physiology, cannot do better than to possess themselves of the manual of Dr. Carpenter. — Medical Examiner . The best and most complete exposd of modern Physiology, in one volume, extant in the English language.— Si. Louis Medical Journal. With such an aid in his hand, there is no excuse for the ignorance often displayed respecting the sub- jects of which it treats. From its unpretending di- mensions, it may not be so esteemed by those anxious to make a parade of their erudition; but whoever masters its contents will have reason to be proud of his physiological acquirements. The illustrations are well selected and finely executed.— Dublin Med. Press. BY the same author. (Nearly Ready.) THE MICROSCOPE AND ITS REVELATIONS. In one handsome volume, with several hundred beautiful illustrations. Various literary engagements have delayed the author's progress with this long expected work. It is now, however, in an advanced state of preparation, and may be expected in a few month?. The importance which the microscope has assumed within the last few years, both as a guide to the practising physician who wishes to avail himself of the progress of his science, and as an indis- pensable assistant to the physiological and pathological observer, has caused the want to be severely felt of a volume which should serve as a guide to the learner and a book of reference to the more advanced student. This want Dr. Carpenter has endeavored to supply in the present volume. His great practical familiarity with the instrument and all its uses, and his acknowledged ability as a teacher, are a sufficient guarantee that the work will prove in every way admirably adapted to its purpose, and superior to any as yet presented to the scientific world. BY THE SAME AUTHOR. A PRIZE ESSAY ON THE USE OF ALCOHOLIC LIQUORS IN HEALTH AND DISEASE. New edition, with a Preface by D. F. Condie, M. D., and explanations of scientific words. In one neat 12mo. volume, pp. 178. {Just Issued.) CHELIUS (J. M.), M. D., Professor of Surgery in the University of Heidelberg, &.C. A SYSTEM OF SURGERY. Translated from the German, and accompanied with additional Notes and References, by John F. South. Complete in three very large octavo volumes, of nearly 2200 pages, strongly bound, with raised bands and double titles. We do not hesitate to pronounce it the best and most comprehensive system of modern surgery with which we are acquainted. — Medico-Chirurgical Re- view. The fullest and ablest digest extant of all that re- lates to the present advanced state of surgical pa- thology. — American Medical Journal. The most learned and complete systematic treatise now extant.— Edinburgh Medical Journal. CLYMER (MEREDITH), M. D., &.c. FEVERS; THEIR DIAGNOSIS, PATHOLOGY, AND TREATMENT. Prepared and Edited, with large Additions, from the Essays on Fever in Tweedie's Library ot Practical Medicine. In one octavo volume, of 600 pages. CHRISTISON (ROBERT), M. D., V. P. R. S. E., &.c. A DISPENSATORY; or, Commentary on the Pharmacopoeias of Great Britain the United States; comprising the Natural History, Description, Chemistry, Pharmacy, Ac- is, Uses, and Doses of the Articles of the Materia Medica. Second edition, revised and im- and I tions proved, with a Supplement containing the most important New Remedies. With copious Addi lions, and two hundred and thirteen large wood-engravings. By 11. Eglesfeld Griffith, M. D. In one very large and handsome octavo volume, of over 1000 pages. It is not needful that w, should compare it with the other pharmacopoeias extant, which enjoy and merit the confidence of the profession : it is enough to say that it appears to us as perfect as a Dispensa- tory, in the present state of pharmaceutical science, could be made. If it omits any details pertaining to this branch of knowledge which the student has a right to expect in such a work, we confess the omis- sion has escaped our scrutiny. We cordially recom- mend this work to such of our readers as are in need of a Dispensatory. They cannot make choice of a better. — Western Journ. of Medicine and Surgery. There is not in any language a more complete and perfect Treatise. — A'. Y. Annalist. In conclusion, we need scarcely say that we strongly recommend this work to all classes of our readers. Asa Dispensatory and commentary on the Pharmacopoeias, it is unrivalled in the English or any other language. — The Dublin Quarterly Journal. We earnestly recommend Dr. Christison's Dis- pensatory to all our readers, as an indispensable companion, not in the Study only, but in the Surgery also. — British and Foreign Medical llevteto. BLANCHARD & LEA'S MEDICAL CONDIE (D. F.), M. D., &c. A PRACTICAL TREATISE ON THE DISEASES OF CHILDREN. Fourth edition, revised and augmented. In one large volume, 8vo., of nearly 750 pages. {Lately Issued.) From the Author's Preface. The demand for another edition has afforded the author an opportunity of again subjecting the entire treatise to a careful revision, and of incorporating in it every important observation recorded since the appearance of the last edition, in reference to the pathology and therapeutics of the several diseases of which it treats. In the preparation of the present edition, as in those which have preceded, while the author has appropriated to his use every important fact that he has found recorded in the works of others, having a direct bearing upon either of the subjects of which he treats, and the numerous valuable observations — pathological as well as practical — dispersed throughout the pages of the medical journals of Europe and America, he has, nevertheless, relied chiefly upon his own observations and experience, acquired during a long and somewhat extensive practice, and under circumstances pe- culiarly well adapted for the clinical study of the diseases of early life. Every species of hypothetical reasoning has, as much as possible, been avoided. The author has endeavored throughout the work to confine himself to a simple statement of well-ascertained patho- logical facts, and plain therapeutical directions — his chief desire being to render it what its title imports it to be, a practical treatise on the diseases of children. Dr. Condie's scholarship, acumen, industry, and practical sense are manifested in this, as in all his numerous contributions to science. — Dr. Holmes's Report to the American Medical Association. Taken as a whole, in our judgment, Dr. Condie's Treatise is the one from the perusal of which the practitioner in this country will rise with the great- est satisfaction — Western Journal of Medicine and Surgery. One of the best works upon the Diseases of Chil- dren in the English language. — Western Lancet. Perhaps the most full and complete work now be- fore the profession of the United States; indeed, we may say in the English language. It is vastly supe- rior to most of its predecessors. — Transylvania Med. Journal. We feel assured from actual experience that no physician's library can be complete without a copy of this work. — N. Y. Journal of Medicine. A veritable pediatric encyclopaedia, and an honor to American medical literature. — Ohio Medical and Surgical Journal. We feel persuaded that the American medical pro- fession will soon regard it not only as a very good, but as the very best "Practical Treatise on the Diseases of Children." — American Medical Journal. We pronounced the first edition to be the best work on the diseases of children in the English language, and, notwithstanding all that has been published, we still regard it in that light. — Medical Examiner. COOPER (BRANSBY B.), F. R. S., Senior Surgeon to Guy's Hospital, &c. LECTURES ON THE PRINCIPLES AND PRACTICE OF SURGERY. In one very large octavo volume, of 750 pages. {Lately Issued.) For twenty-five years Mr. Bransby Cooper has been surgeon to Guy's Hospital; and the volume before us may be said to consist of an account of the results of his surgical experience during that long period. We cordially recommend Mr. Bransby Cooper's Lectures as a most valuable addition to our surgical literature, and one which cannot fail to be of service both to students and to those who are actively engaged in the practice of their profes- sion. — The Lancet. COOPER (SIR ASTLEY P.), F. R. S., &c. A TREATISE ON DISLOCATIONS AND FRACTURES OF THE JOINTS. Edited by Bransby B. Cooper, F. R. S., &c. With additional Observations by Prof. J. C. Warren. A new American edition. In one handsome octavo volume, of about 500 pages, with numerous illustrations on wood. BY THE SAME AUTHOR. ON THE ANATOMY AND TREATMENT OF ABDOMINAL HERNIA. One large volume, imperial 8vo., with over 130 lithographic figures. BY THE SAME AUTHOR. ON THE STRUCTURE AND DISEASES OF THE TESTIS, AND ON THE THYMUS GLAND. One vol. imperial 8vo., with 177 figures, on 2d plates. BY THE SAME AUTHOR. ON THE ANATOMY AND DISEASES OF THE BREAST, with twenty- five Miscellaneous and Surgical Papers. One large volume, imperial 8vo., with 252 figures, on 36 plates. These last three volumes complete the surgical writings of Sir Astley Cooper. They are very handsomely printed, with a large number of lithographic plates, executed in the best style, and are preseuted at exceedingly low prices. CARSON (JOSEPH), M. D., Professor of Materia Medica and Pharmacy in the University of Pennsylvania. SYNOPSIS OF THE COURSE OF LECTURES ON MATERIA MEDICA AND PHARMACY, delivered in the University of Pennsylvania. Second and revised edi- tion. In one very neat octavo volume, of 208 pages. {Note Heady.) AND SCIENTIFIC PUBLICATIONS. CHURCHILL (FLEETWOOD), M. D., M. R. I. A. ON THE THEORY AND PRACTICE OP MIDWIFERY. A new American, from (he last and improved English edition. Edited, with Notes and Additions, by D. Francis Condie, M. D., author of a "Practical Treatise on the Diseases of Children," &c. With 139 illustrations. In one very handsome octavo volume, pp. 510. {Lately Issued.) To bestow prai se on a book that has received such marked approbation would be superfluous. We need only say, therefore, that if the first edition was thought worthy of a favorable reception by the medical public, we can confidently affirm that this will be found much more so. The lecturer, the practitioner, and the student, may all have recourse to its pages, and derive from their perusal much in- terest and instruction in everything; relating to theo- retical and practical midwifery. — Dublin Quarterly Journal of Medical Science. A work of very great merit, and such as we can confidently recommend to the study of every obste- tric practitioner. — London Medical Gazette. This is certainly the most perfect system extant. It is the best adapted for the purposes of a text- book, and that which he whose necessities confine him to one book, should select in preference to all others. — Southern Medical and Surgical Journal. The most popular work on midwifery ever issued from the American press. — Charleston Med. Journal. Were we reduced to the necessity of having but one work on midwifery, and permitted to choose, we would unhesitatingly take Churchill. — Western Med. and Surg. Journal. It is impossible to conceive a more useful and elegant manual than Dr. Churchill's Practice of Midwifery. — Provincial Medical Journal. Certainly, in our opinion, the very best work on the subject which exists. — N. Y. Annalist. No work holds a higher position, or is more de- serving of being placed in the hands of the tyro, the advanced student, or the practitioner. — Medical Examiner. Previous editions, under the editorial supervision of Prof R. M. Huston, have been received with marked favor, and they deserved it; but this, re- printed from a very late Dublin edition, carefully revised and brought up by the author to the present time, does present an unusually accurate and able exposition of every important particular embraced in the department of midwifery. * * The clearness, directness, and precision of its teachings, together with the great amount of statistical research which its text exhibits, have served to place it already in the foremost rank of works in this department of re- medial science. — N. O. Med. and Surg. Journal. In our opinion, it forms one of the best if not the very best text-book and epitome of obstetric science which we at present possess in the English lan- guage. — Monthly Journal of Medical Science. The clearness and precision of style in which it is written, and the great amount of statistical research which it contains, have served to place it in the first rank of works in this departmentof medical science. — N. Y. Journal of Medicine. Few treatises will be found better adapted as a text-book for the student, or as a manual for the frequent consultation of the young practitioner. — American Medical Journal. BY THE SAME AUTHOR. ON THE. DISEASES OF INFANTS AND CHILDREN. In one large and handsome volume of over 600 pages. We regard this volume as possessing more claims to completeness than any other of the kind with which we are acquainted. Most cordially and earn- estly, therefore, do we commend it to our profession- al brethren, and we feel assured that the stamp of their approbation will in due time be impressed upon it. After an attentive perusal of its contents, we hesitate not to say, that it is one of the most com- prehensive ever written upon the diseases of chil- dren, and that, for copiousness of reference, extentof research, and perspicuity of detail, it is scarcely to be equalled, and not to be excelled, in any lan- guage. — Dublin Quarterly Journal. After this meagre, and we know, very imperfect notice of Dr. Churchill's work, we snail conclude by saying, that it is one that cannot fail from its co- piousness, extensive research, and general accuracy, to exalt still higher the reputation of the author in this country. The American reader will be particu- larly pleased to find that Dr. Churchill has done full justice throughout his work to the various American authors on this subject. The names of Dewees, Eberle, Condie, and Stewart, occur on nearly every page, and these authors are constantly referred to by the author in terms of the highest praise, and with the most liberal courtesy. — The Medical Examiner. The present volume will sustain the reputation acquired by the author from his previous works. The reader will find in it full and judicious direc- tions for the management of infants at. birth, and a compendious, but clear account of the diseases to which children are liable, and the most successful mode of treating them. We must not close this no- tice without calling attention to the author's style, which is perspicuous and polished to a degree, we regret to say, not generally characteristic of medica. works. We recommend the work of Dr. Churchill most cordially, both to students and practitioners, as a valuable and reliable guide in the treatment of the diseases of children. — Am. Journ. of the Med. Sciences. We know of no work on this department of Prac- tical Medicine which presents so candid and unpre- judiced a statement or posting up of our actual knowledge as this. — N. Y. Journal of Medicine. Its claims to merit both as a scientific and practi- cal work, are of the highest order. Whilst we would not elevate it above every other treatise on the same subject, we certainly believe that very few are equal to it, and none superior. — Southern Med. and Surgical Journal. BY THE SAME AUTHOR. ESSAYS ON THE PUERPERAL FEVER, AND OTHER DISEASES PE- CULIAR TO WOMEN. Selected from the writings of British Authors previous to the close of the Eighteenth Century. In one neat octavo volume, of about four hundred and fifty pages. To these papers Dr. Churchill has appended notes, embodying whatever information has been laid be- fore the profession since their authors' time. He has also prefixed to the Essays on Puerperal Fever, which occupy the larger portion of the volume, an interesting historical sketch of the principal epi- demics of that disease. The whole forms a very valuable collection of papers, by professional writers of eminence, on some of the most important accident! to which the puerperal female is liable. — American Journal of Medical Sciences. 10 BLANCHARD & LEA'S MEDICAL CHURCHILL (FLEETWOOD), M. D., M. R. I. A., &c. ON THE DISEASES OF WOMEN; including those of Pregnancy and Child- bed. A new American edition, revised by the Author. With Notes and Additions, by D Fran- cis Condie, M. D., author of "A Practical Treatise on the. Diseases of Children." In one large and handsome octavo volume, with wood-cuts, pp. 684. [Just Issued.) We now regretfully take, leave of Dr. Churchill's book. Had our typographical limits permitted, we should gladly have borrowed more from its richly stored pages. In conclusion, wo heartily recom- mend it to the profession, and would at the same time express our firm conviction that it will not only add to the reputation of its author, but will prove a work of great and extensive utility to obstetric practitioners. — Dublin Medical Press. Former editions of this work have been noticed in previous numbers of the Journal. The sentiments of high commendation expressed in those notices, have only to be repeated in this; not from the fact that the profession at large are not aware of the high merits which this work really possesses, but from a desire to see the principles and doctrines therein contained more generally recognized, and more uni- versally carried out in practice. — N. Y. Journal of Medicine. We know of no author who deserves that appro- bation, on " the diseases of females," to the same txrent that Dr. Churchill does. His, indeed, is the only thorough treatise we know of on the subject; and it may be commended to practitioners and stu- dents as a masterpiece in its particular department. The former editions of this work have been com- mended strongly in this journal, and they have won their way to an extended, and a well-deserved popu- larity. This fifth edition, before us. is well calcu- lated to maintain Dr. Churchill's high reputation. It was revised and enlarged by the author, for his American publishers, and it seems to us that there is scarcely any species of desirable information on its subjects that may not be found in this work. — The Western Journal of Medicine and Surgery. AVe are gratified to announce a new and revised edition of Dr. Churchill's valuable work on the dis- eases of females We have ever regarded it as one of the very best works on the subjects embraced within its scope, in the English language; and the present edition, enlarged and revised by the author, renders it still more entitled to the confidence of the profession. The valuable notes of Prof. Huston have been retained, and contribute, in no small de- gree, to enhance the value of the work. It is a source of congratulation that the publishers have permitted the author to be, in this instance, his own editor, thus securing all the revision which an author alone is capable of making. — The Western Lancet. Asa comprehensive manual for students, or a work of reference for practitioners, we only speak with common justice when we say that it surpasses any other that has ever issued on the same sub- ject from the British press. — The Dublin Quarterly Journal. DICKSON (S. H.), M. D., Professor of Institutes and Practice of Medicine in the Medical College of South Carolina. ELEMENTS OF MEDICINE; a Compendious View of Pathology and Thera- petitics, or ihe History and Treatment of Diseases. In one large and handsome octavo volume of nearly 800 pages (Noiv Ready.) As a text- book on the Practice of Medicine for the student, and as a condensed work of reference for the practitioner, this volume will have strong claims on the attention of the American profession. Few physicians have had wider opportunities, than the author, for observation and experience, and few perhaps have used them belter. As the result of a life of study and practice, therefore, the present volume will doubtless be received with the welcome it deserves. From the Preface. Tffe present volume is inlended as an aid to young men who have engaged in the study of medi- cine, to physician-; who have recently assumed the responsibilities of practice, and to my fellow professors of the Institutes of Medicine, and private instructors who have felt the difficulty of com- municating to the two (irst classes the knowledge which they are earnestly seeking to acquire. Having been a teacher of medicine for thirty years, and a student more than forly, I must have accumulated some experience in both characters. I have prepared and printed for those in attend- ance on my lectures many successive manuals or text-books. I have also written and published several volumes on medical subjects in general. The following pages are ihe result of a careful collation of all that has been esteemed valuable in bolh, with such matter as continued study and enlarged experience has enabled me to add. DEWEES (W. P.), M.D., &c. A COMPREHENSIVE SYSTEM OF MIDWIFERY. Illustrated by occa- sional Cases and many Engravings. Twelfth edition, with the Author's last Improvements and Corrections. In one octavo volume, of 600 pages. (Just Issued.) BY THE SAME AUTHOR. A TREATISE ON THE PHYSICAL AND MEDICAL TREATMENT OF CHILDREN. Tenth edition. In one volume, octavo, 548 pages. (Just Issued.) BY THE SAME AUTHOR. A TREATISE ON THE DISEASES OF FEMALES. one volume, octavo, 532 pages, with plates. (Just Issued.) Tenth edition. In DANA (JAMES D). ZOOPHYTES AND CORALS. In one volume, imperial quarto, extra cloth, with wood-cuts. Also, AN ATLAS,- in one volume, imperial folio, with sixty-one magnificent plates, colored after nature. Bound in half morocco. DE LA BECHE (SIR THE GEOLOGICAL OBSERVER volume, of 700 pages. With over three hundred wood-cuts HENRY T.), F. R. S., &c. In one very large and handsome octavo (Lately Issued.) AND SCIENTIFIC PUBLICATIONS. a! DRUITT (ROBERT), M.R. C.S., &c. THE PRINCIPLES AND PRACTICE OF MODERN SURGERY. A new American, from, the improved London edition. Edited by F. W. Sargent, M. D., author of "Minor Surgery," &c. Illustrated with one hundred and ninety-three wood-engravings. In one very handsomely printed octavo volume, of 576 large pages. Dr. Druitt's researches into the literature of his I is really practically useful at the bedside will be ubject have been not only extensive, but well di- found in a form at once clear, distinct, and interest- rected ; the most discordant authors are fairly and impartially quoted, and, while due credit is given to each, their respective merits are weighed with an unprejudiced hand. The grain of wheat is pre- served, and the chaff is unmercifully stripped off. The arrangement is simple and philosophical, and the style, though clear and interesting, is so precise, that the book contains more information condensed into a few words than any other surgical work with which we are acquainted. — London Medical Times and Gazette, February 18, 1S5I. No work, in our opinion, equals it in presenting so much valuable surgical matter in so small a compass. — St. Louis Med. and Surgical Journal. Druitt's Surgery is too well known to the Ameri- can medical profession to require its announcement anywhere. Probably no work of the kind has ever been more cordially received and extensively circu- lated than this. The fact that it comprehends in a comparatively small compass, all the essential ele- ments of theoretical and practical Surgery — that it is found to contain reliable and authentic informa- tion on the nature and treatment of nearly all surgi- cal atfections — is a sufficient reason for the liberal patronage it has obtained. The editor, Dr. F. W. Sargent, has contributed much to enhance the value of the work, by such American improvements as are calculated more perfectly to adapt it to our own views and practice in this country. It abounds everywhere with spirited and life-like illustrations, which to the young surgeon, especially, are of no minor consideration. Every medical man frequently needs just such a work as this, for immediate refe- rence in moments of sudden emergency, when he has not time to consult more elaborate treatises. — The Ohio Medical and Surgical Journal. The author has evidently ransacked every stand- ard treatise of ancient and modern times, and all that ing. — Edinburgh Monthly Medical Journal. Druitt's work, condensed, systematic, lucid, and practical as it is, beyond most works on Surgery accessible to the American student, has had much currency in this country, and under its present au- spices promises to rise to yet higher favor. — The Western Journal of Medicine and Surgery. The most accurate and ample resume of the pre- sent state of Surgery that we are acquainted with. — Dublin Medical Journal. A better book on the principles and practice of Surgery as now understood in England and America, has not been given to the profession. — Boston Mtdi- cal and Surgical Journal. An unsurpassable compendium, not only of Sur- gical, but of Medical Practice. — London Medical Gazette. This work merits our warmest commendations, and we strongly recommend it to young surgeons as an admirable digest of the principles and practice of modern Surgery. — Medical Gazette. It maybe said with truth that the work of Mr. Druitt affords a complete, though brief and con- densed view, of the entire field of modern surgery. We know of no work on the same subject having the appearance of a manual, which includes so many topics of interest to the surgeon ; and the terse man- ner in which each has been treated evinces a most enviable quality of mind on the part of the author, who seems to have an innate power of searching out and grasping the leading facts and features of the most elaborate productions of the pen. It is a useful handbook for the practitioner, and we should deem a teacher of surgery unpardonable who did not recommend it to his pupils. In our own opinion, it is admirably adapted to the wants of the student. — Provincial Medical and Surgical Journal. DUNGLISON, FORBES, TWEEDIE, AND CONOLLY. THE CYCLOPAEDIA OF PRACTICAL MEDICINE: comprising Treatises on the Nature and Treatment of Diseases, Materia Medica, and Therapeutics, Diseases of Women and Children, Medical Jurisprudence, &c. &c. In four large super royal octavo volumes, of 3254 double-columned pages, strongly and handsomely bound. *#* This work contains no less than four hundred and eighteen distinct treatises, contributed by eix-ty-eighl distinguished physicians. The most complete work on Practical Medicine extant; or, at least, in our language.— Buffalo Medical and Surgical Journal. For reference, it is above all price to every prac- titioner. — Western Lancet. One of the most valuable medical publications of the day — as a work of reference it is invaluable. — Western Journal of Medicine and Surgery. It has been to us, both as learner and teacher, a work for ready and frequent reference, one in which modern English medicine is exhibited in the most advantageous light. — Medical Examiner. We rejoice that this work is to be placed within the reach of the profession in this country, it being unquestionably one of very great value to the prac- titioner. This estimate of it has not been formed from a hasty examination, but after an intimate ac- quaintance derived from frequent consultation of it during the past nine or ten years. The editors are practitioners of established reputation, and the list of contributors embraces many of the most eminent professors and teachers of London, Edinburgh, Dub- lin, and Glasgow. It is, indeed, the great merit of this work that the principal articles have been fur- nished by practitioners who have not only devoted especial attention to the diseases about which they have written, but have also enjoyed opportunities for an extensive practical acquaintance with them, and whose reputation carries the assurance of their competency justly to appreciate the opinions of others, while it stamps their own doctrines with high and just authority. — American Medical Journ. DUNGLISON (ROBLEY), M.D., Professor of the Institutes of Medicine in the Jefferson Medical College, Philadelphia. HUMAN HEALTH; or, the Influence of Atmosphere and Locality, Change of Air and Climate, Seasons, Food, Clothing, Bathing, Exercir-e, Sleep, fee. &0 , on Healthy Man ; constituting Elements of Hygiene. Second edition, with many modifications and additions. In one octavo volume, of 464 pages. 12 BLANCHARD & LEA'S MEDICAL DUNGLISON (ROBLEY), M.D., Professor of Institutes of Medicine in the Jefferson Medical College, Philadelphia. MEDICAL LEXICON; a Dictionary of Medical Science, containing a concise Explanation of'the various Subjects and Terms of Physiology, Pathology, Hygiene, Therapeutics, Pharmacology, Obstetrics, Medical Jurisprudence, &c. Wilh the French and other Synonymes; Notices of Climate and of celebrated Mineral Waters; Formulae for various Officinal, Empirical, and Dietetic Preparations, etc. Twelfth edition, revised. In one very thick octavo volume, ot over nine hundred large double-columned pages, strongly bound in leather, with raised bands. (Just Issued.) Every successive edition of this work bears the marks of the industry of the author, and of his determination to keep it fully on a level with the most advanced state of medical science. Thus nearly fifteen thousand words have been added to it within the last few vears. As a complete Medical Dictionary, therefore, embracing over FIFTY THOUSAND DEFINITIONS, in all the branches of the science, it is presented as meriting a continuance of the great favor and popularity which have carried it, within no very long space of time, to a twelfth edition. Every precaution has been taken in the preparation of the present volume, to render its mecha- nical execution and typographical accuracy worthy of its extended reputation and universal use. The very extensive additions have been accommodated, without materially increasing the bulk of the volume by the employment of a small but exceedingly clear type, cast for this purpose. The press has been watched with great care, and every effort used to insure the verbal accuracy so ne- cessary to a work of this nature. The whole is printed on fine white paper ; and, while thus exhi- biting in every respect so great an improvement over former issues, it is presented at the original exceedingly low price. We welcome it cordially ; it is an admirable work, and indispensable to all literary medical men. The labor which has been bestowed upon it is something prodigious. The work, however, has now been done, and we are hnppy in the thought that no hu- man bring will have again to undertake the same gigantic task. Revised and corrected from time to time, Dr. Dunglison's " Medical Lexicon" will last for centuries. — British and Foreign Med. Chirurg. Review. The fact that this excellent and learned work has passed through eight editions, and that a ninth is rendered necessary by the demands of the public, affords a sufficient evidence of the general apprecia- tion of Dr. Dunglison's labors by the medical pro- fession in England and America. It is a book which will be of great service to the student, in teaching him the meaning of all the technical terms used in medicine, and will be of no less use to the practi- tioner who desires to keep himself on a level with the advance of medical science. — London Medical Times and Gazette. In taking leave of our author, we feel compelled to confess that his work bears evidence of almost incredible labor having been bestowed upon its com- position. — Edinburgh Journal of Med. Sciences. A miracle of labor and industry in one who has written able and voluminous works on nearly every branch of medical science. There could be no more useful book to the student or practitioner, in the present advancing age, than one in which would be found, in addition to the ordinary meaningand deri- vation of medical terms — so many of which are of modern introduction — concise descriptions of their explanation and employment; and all this and much more is contained in the volume before us. It is therefore almost as indispensable to the other learned professions as to our own. In fact, to all who may have occasion to ascertain the meaning of any word belonging to the many branches of medicine. From a careful examination of the present edition, wecan vouch for its accuracy, and for its being brought quite up to the date of publication ; the author states in his preface that hehusadded to it aboutfonr thou- sand terms, which are not to be found in the piece- readers to its peculiar merits; and we need do little more than state, in reference to the present reissue, that, notwithstanding the large additions previously made to it, no fewer than four thou- sand terms, not to be found in the preceding edi- tion, are contained in the volume hi fore us. — Whilst it is a wonderful monument of its author's erudition and industry, it is also a work of great practical utility, as we can testify from our own experience; for we keep it constantly within our reach, and make very frequent reference to it, nearly always finding in it the information we seek. — British and Foreign Med.-Chirurg. Review. It has the rare merit that it certainly has no rival in the English language for accuracy and extent of references. The terms generally include short physiological and pathological descriptions, so that, as the author justly observes, the reader does not possess in this work a mere dictionary, but a book, which, while it instructs him in medical etymo- logy, furnishes him with a large amount of useful information. The author's labors have been pro- perly appreciated by his own countrymen ; and we can only confirm their judgment, by recommending this most useful volume to the notice of our cisat- lantic readers. No medical library will be complete without it. — London Med. Gazette. It is certainly more complete and comprehensive than any with which we are acquainted in the English language. Few, in fact, could be found belter qualified than Dr. Dunglison for the produc- tion of such a work. Learned, industrious, per- severing, and accurate, he brings to the task all the peculiar talents necessary for its successful performance; while, at the same time, his fami- liarity with the writings of the ancient and modern '• masters of our art," renders him skilful to note the exact usage of the several terms of science, and the various modifications which medical term inology has undergone with the change of theo- ries or the progress of improvement. — American Journal of the Medical Sciences. One of the most complete and copious known to the cultivators of medical science. — Boston Med. ding one. — Dublin Quarterly Journal of Medical Journal. Sci-nc.s. i Tne most comprehensive and best English Die- On the appearance of the last edition of this I tionary of medical terms extant. — Buffalo Medical valuable work, we directed the attention of our | Journal. BY THE SAME AUTHOR. THE PKACTICE OF MEDICINE. A Treatise on Special Pathology and The rapeuties. Third Edition. In two large octavo volumes, of fifteen hundred pages. Upon every topic embraced in the work the latest information will be found carefully posted up. — Medical Examiner . The student of medicine will find, in these two elegant volumes, a mine of facts, a gathering of precepts and advice from the world of experience, that will nerve nim with courage, and faithfully direct him in his efforts to relieve the physical suf- ferings of the race.— Boston Medical and Surgical Journal. It is certainly the most complete treatise of which we haveany knowledge. — Western Journal of Medi- cine and Surgery. One of the most elaborate treatises of the kind we have. — Southern Med. and Surg. Journal. AND SCIENTIFIC PUBLICATIONS. 13 DUNGLISON (ROBLEY), M.D., Professor of Institutes of Medicine in the Jefferson Medical College, Philadelphia. HUMAN PHYSIOLOGY. Seventh edition. Thoroughly revised and exten- sively modified and enlarged, with nearly five hundred illustrations. In two large and hand- somely printed octavo volumes, containing nearly 1450 pages. It has long since taken rank as one of the medi- cal classics of our language. To say that it is by far the best text-book of physiology ever published in this country, is but echoing the general testi- mony of the profession. — N. Y. Journal of Medicine . There is no single book we would recommend to the student or physician, with greater confidence than the present, because in it will be found a mir- ror of almost every standard physiological work of the day. We most cordially recommend the work to every member of the profession, and no student should be without it. It is the completest work on Physiology in the English language, and is highly creditable to the author and publishers.— Canadian Medical Journal. The most complete and satisfactory system of Physiology in the English language. — Amer. Med. Journal . The best work of the kind in the English lan- guage. — Siliiman's Journal. The most full and complete system of Physiology in our language. — Western Lancet. BY THE SAME author. (Just Issued.) GENEEAL THERAPEUTICS AND MATERIA MEDICA; adapted for a Medical Text-book. Fifth edition, much improved. With one hundred and eighty-seven illus- trations. In two large and handsomely printed octavo vols., of about 1100 pages. The new editions of the United States Pharmacopoeia and those of London and Dublin, have ren- dered necessary a thorough revision of this work. In accomplishing ibis the author has spared no pains in rendering it a complete exponent of all that is new and reliable, both in the departments of Therapeutics and Materia Medica. The book has thus been somewhat enlarged, and a like im- provement will be found in every department of its mechanical execution. As a convenient text- book for the student, therefore, containing within a moderate compass a satisfactory resume of its important subject, it is again presented as even more worthy than heretofore of the very great favor which it has received. As a text-book for students, for whom it is par- ticularly designed, we know of none superior to it. — St. Louis Medical and Surgical Journal. In this work of Dr. Dunglison, we recognize the same untiring industry in the collection and em- bodying of facts on the several subjects of which he treats, that has heretofore distinguished him, and we cheerfully point to these volumes, as two of the most interesting that we know of. In noticing the additions to this, the fourth edition, there is very little in the periodical or annual literature of the profession, published in the interval which has elapsed since the issue of the first, that has escaped the careful search of the author. As a book for reference, it is invaluable. — Charleston Med. Jour- nal and Review. It may be said to be the work now upon the sub- jects upon which it treats. — Western Lancet. It purports to be a new edition, but it is rather a new book, so greatly has it been improved, both in the amount and quality of the matter which it contains. — iV. O. Medical and Surgical Journal. We bespeak for this edition, from the profession, an increase of patronage over any of its former ones, on account of its increased merit. — N. Y. Journal of Medicine. We consider this work unequalled. and Surg. Journal. -Boston Med. BY THE SAME AUTHOR. NEW REMEDIES, WITH FORMULA FOR THEIR ADMINISTRATION. Sixth edition, with extensive Additions. In one very large octavo volume, of over 750 pages. One of the most useful of the author's works. — diseases and for remedies, will be found greatly to Southern Medical and Surgical Journal. enhance its value. — New York Med. Gazette. This well-known and standard book has now reached its sixth edition, and has been enlarged and improved by the introduction of all the recent gifts to therapeutics which the last few years have so richly produced, including the anaesthetic agents, &c. This elaborate and useful volume should be found in every medical library, for as a book of re- ference, for physicians, it is unsurpassed by any other work in existence, and the double index for The great learning of the author, and his remark- able industry in pushing his researches into every source whence information is derivable, has enabled him to throw together an extensive mass of facts and statements, accompanied by full reference to authorities; which last feature renders the work practically valuable to investigators who desire to examine the original papers. — The American Journal of Pharmacy. DE JONGH (L. J.), M. D., &c. THE THREE KINDS OF COD-LIVER OIL, comparatively considered, with their Chemical and Therapeutic Properties. Translated, with an Appendix and Cases, by Edward Carey, M. D. To which is added an article on the subject from "Dunglison on New Remedies." In one small 12mo. volume, extra cloth. DAY (GEORGE E.), M . D. A PRACTICAL TREATISE ON THE DOMESTIC MANAGEMENT AND MORE IMPORTANT DISEASES OF ADVANCED LIFE. With an Appendix on a new and successful mode of treating Lumbago and other lorms of Chronic Rheumatism. One volume, octavo, 226 pages. FRICK (CHARLES), M. D. RENAL AFFECTIONS; their Diagnosis and Pathology. One volume, royal 12mo., extra cloth. With illustrations. 14 BLANCHARD & LEA'S MEDICAL ERICHSEN (JOHN), Professor of Surgery in University College, London, &c. THE SCIENCE AND ART OP SURGERY; being a Treatise on Surgical Injuries, Diseases, and Operations. Edited by John H. Brinton, M. D. Illustrated with fhree hundred and eleven engravings on wood. In one large and handsome octavo volume, of over nine hundred closely printed pages. {Just Issued.) It is, in our humble judgment, decidedly tlie best book of the kind in the English language. Strange that just such books are notoftener produced by pui> lie teachers of surgery in this country and Great Britain Indeed, it is a matter of great astonishment. but no les* true than astonishing, that of the many works on surgery republished in this country within i tie jast fifteen or twenty years as text-books for medical siuiients, this is the only one, that even ap- proximates to ihr fulfilment of the peculiar wants Ol young men just entering upon the study of thi* branch of ihe profession. — Western Jour. of Med. and Surgery. Embracing, as will be perceived, the whole surgi- cal domarii, and each division of itself almost com- plete and perfect, each chapter full and explicit, each subject faithfully exhibited, we can only express our exiimaie ol it in the aggregate. We consider it an excellent contribution to surgery, as probably the lies! single volume now extant on ihe subject, and with great pleasure we add it 10 our text books — Nashville. Journal of Medicine and Surgery. lis value is greatly enhanced by a very copious well-arranged index. We regard this as one of the most valuable contributions to modern surgery. To one entering his novitiate of practice, we regard il the most serviceable guide which he can consult. He will find a fulness of detail leading him through every step of the operation, and not deserting him until the final issue of the case is decided. For the same rea- son we recommend it to those whose routine of prac- tice lies in such parts of the country that they must rarely encounter cases requiring surgical manage- ment. — Stethoscope. Prof. Erichsen's work, for its size, has not been surpassed; his nine hundred and eight pages, pro- fusely illustrated, are rich in physiological, patholo- gical, and operative suggestions, doctrines, details, and processes; and will prove a reliable resource for information, boih to physician and surgeon, in trie hour of peril — iY. 0. Med. and Surg Journal. We are acquainted with nn other work wherein so much good sense, sound principle, and practical inferences, stamp every page. To say more of the volume would be useless; to say less would be doing injustice to a production which we consider above all others at the present day, and superior and more complete than the many excellent treatises ot the Knglish and Scotch surgeons, and this is no small encomium. — American Lancet. ELLIS (BENJAMIN), M.D. THE MEDICAL FORMULARY : being a Collection of Prescriptions, derived from Ihe writings and praciice of many of the most eminent physicians of America and Europe. Together with the usual Dietetic Preparations and Antidotes for Poisons. To which is added an Appendix, on the Endermic use of Medicines, and on the use of El her and Chloroform. The whole accompanied with a few brief Pharmaceutic and Medical Observations. Tenth edition, revised and much extended by Robert P. Thomas, M. D., Professor of Materia Mcdica in the Philadelphia College of Pharmacy. In one neal octavo volume, of two hundred and ninety-six pages. (Lately Issued.) After an examination of the new matter and the alterations, we believe the reputation of the work built up by the author, and the late distinguished editor, will continue to flourish under the ao spices of the present editor, who has the industry and accu- racy, and, we would say, conscientiousness requi- site for the responsible task. — American Journal of Pharmacy, March, 1&J4. It will prove particularly useful to students and young practitioners, as the most important prescrip- tions employed in modern practice, which lie scat- tered through our medical literature, are here col- lected and conveniently arranged for reference. — Charleston Med. Journal and Review. FOWNES (GEORGE), PH. D., &.c. ELEMENTARY CHEMISTRY; Theoretical and Practical. With numerons illustrations. A new American, from the last and revised London edition. Edited, wilh Addi- tions, by Robert Bridges, M. D. In one large royal 12mo. volume, of over 550 pages, wilh 181 wood-cuts, sheep, or extra cloth. (Now Ready.) We know of no better text-book, especially in the l The work of Dr. Fownes has long been before difficult department of organic chemistry, upon the public, and its merits have been fully appreci- which it is particularly full and satisfactory. We ated as the best text-book on chemistry now in would recommend it to preceptors as a capital existence. We do not. of course, place it in a rank " office book" for their students who are beginners superior to the works of Erande, Graham, Turner, in Chemistry. It is copiously illustrated with ex- Gregory, or Gmelin, but we say that, as a work cellent wood-cuts, and altogether admirably "got for students, it is preferable to any of them. — Lon.- up." — IV. J. Medical Reporter, March, 1S54. don Journal of Medicine. A standard manual, which has long enjoyed the reputation of embodying much knowledge in a .small space. The author baB achieved the difficult task of condensation with masterly tact. His book is con- cise without being dry, and brief without being too dogmatical or general. — Virginia Med. and Surgical Journal. A work well adapted to the wants of the student. It. is an excellent exposition of the chief doctrines and factsof modern chemistry. The size of the work, and still more the condensed yet perspicuous style in which it is written, absolve it from the charges very properly urged against most manuals termed popular. — Edinburgh Monthly Journal of Medical Science. FLINT (AUSTIN), M . D., Professor of the Theory and Practice of Medicine in the University of Louisville, &c. PHYSICAL EXPLORATION AND DIAGNOSIS OF DISEASES AFFECT- ING THE ORGANS OF RESPIRATION. In one handsome octavo volume. (Now Ready.) The reputation already acquired by the author with respect to his researches on this and kindred topics, is sufficient guarantee that he will accomplish his object in presenting the student with a good practical text-book, which will facilitate the acquirement of a knowledge of this dilficult sub- ject. The work will be ready in time for the Fall sessions. AND SCIENTIFIC PUBLICATIONS. IS FERGUSSOM (WILLIAM), F. R. S., Professor of Surgery in King's College, London, &c. A SYSTEM OF PRACTICAL SURGERY. Fourth American, from the third and enlarged London edition. In one large and beautifully printed octavo volume, of about seven hundred pages, with three hundred and ninety-three handsome illustrations. {Just Issued.) The most important subjects in connection with I No work was ever written which more nearly practical surgery which have been more recently comprehended the necessities of the student and brought under the notice of, and discussed by, the | practitioner, and was more carefully arranged to surgeons of Great Britain, are fully and dispassion ately considered by Mr. Fergusson, and that which was before wanting has now been supplied, so that we can now look upon itasa work on practical sur- gery instead of one on operative surgery alone. There was some ground formerly for the complaint before alluded to, that it dwelt too exclusively on operative surgery ; but this defect is now removed, and the book is more than ever adapted for the pur- poses of the practitioner, whether he confines him- self more strictly to the operative department, or follows surgery on a more comprehensive scale. — Medical Times and Gazette. that single purpose than this. — N. Y. Mud. and Surg. Journal. The addition of many new pages makes this work more than ever indispensable to the student and prac- titioner. — Ranking- s Abstract. Among the numerous works upon surgery pub- lished of late years, we know of none we value more highly than the one before us. It is perhaps the very best we have for a text-book and for ordi- nary reference, being concise and eminently practi- cal. — Southern Med. and Surg. Journal. GRAHAM (THOMAS), F. R.S., Professor of Chemistry in University College, London, &c. THE ELEMENTS OF CHEMISTRY. Including the application of the Science to the Arts. With numerous illustrations. With Notes and Additions, by Robert Bridges, M. D., &c. ecc. Second American, from the second and enlarged London edition PART I. (Lately Issued) large 8vo., 430 pages, 185 illustrations. PART II. {Preparing) to match. The great changes which the science of chemistry has undergone within the last few years, ren- der a new edition of a treatise like the present, almost a new work. The author has devoted several years to the revision of his treatise, and has endeavored to embody in it every fact and inference of importance which has been observed and recorded by the great body of chemical investigators who are so rapidly changing the face of the science. In this manner the work has been greatly increased in size, and the number of illustrations doubled ; while the labors of the editor have been directed towards the introduction of such matters as have escaped the attention of the author, or as have arisen since the publication of the first portion of this edition in London, ml8.'")0. Printed in handsome style, and at a very low price, it is therefore confidently presented to the pro- fession and the student as a very complete and thorough text-book of this important subject. GRIFFITH (ROBERT E.), M. D., &c. A UNIVERSAL FORMULARY, containing the methods of Preparing and Ad- ministering Officinal and other Medicines. The whole adapted to Physicians and Pharmaceu- tists. Second Edition, thoroughly revised, with numerous additions, by Robert P. Thomas, M. D., Professor of Materia Medica in the Philadelphia College of Pharmacy. In one large and handsome octavo volume, of over six hundred pages, double columns. (Just Issued.) It was a work requiring much perseverance, and j It is one of the most useful books a country practi- when published was looked upon a< by far the best work of its kind lhat had issued from the American press, being free of much of lhe trashy, and embrac- ing most of the non-officinal formulae used or known in American, English, or French practice, arranged under the heads of'the several consiitueutdrugs. plac- ing the receipt under its more important constituent. Prof Thomas has certainly "improved." as well as added o this Formulary, and has rendered it addition- ally deserving of the confidence of pharmaceutists and physicians. — American Journal of Pharmacy. We are happy to announce a new and improved edition of litis, one of lhe most valuable and useful works that have emanated from an American pen. It would do credit to any country, and will be found of daily usefulness to practitioners of medicine; it is belter adapted 10 their purposes than the dispen?ato rie&.— Southern Med. and Surg. Journal. A new edition of this well-known work, edited by R. P. Thomas, M D., affords occasion for renewing our commendation of so useful a handbook, which ought to be universally studied by medical men of every class, ami made use of by way of reference by office pupils, as a standard authority. It has been much enlarged, and now condenses a vast amount of needful and necessary knowledge in small com- pass. The more of such books the better for the pro- fession and the public— N. Y. Med. Gazette. lioner can possibly have in his possession. — Medical Chronicle. The amount of u=efu l.every-day matter, for a prac- ticing physician, is really immense.— Boston Med. and Surg. Journal. Tbi= is a work of six hundred and fifty one pasres, embracing all on the subject of preparing and admi- nistering medicines that can be desired by the. physi- cian and pharmaceutist. — Western Lancet. In short, it is full and complete work of the kind, and should be m the hands of every physician and apothecary. O ■ Med. and Surg. Journal. We predic a great sale for this work, and we espe- cially recommend it to all medical teachers. — Rich- mond Stethoscope. This edition of Dr Griffith's work has been greatly improved by the revision and ample additions of Dr. Thomas, ami is now. we believe, one of the most complete works of it* kind in any language. The additions amount to about seventy pages, and no effort has been spared to include in them all the re- cent improvements which have been published in medical journals, and systematic, treatises. A work of this kind appears io us indispensable to the physi- cian, and lh»reis none we can more cordially recom- mend. — iV. JT. Journal of Medicine. BY THE SAME AUTHOR. MEDICAL BOTANY; or, a Description of all the more important Plants used in Medicine, and of their Properties, Uses, and Modes of Administration. In one large octavo volume, of 704 pages, handsomely printed, with nearly 350 illustrations on wood. GREGORY (WILLIAM), F. R. S. E., LETTERS TO A CANDID INQUIRER ON ANIMAL In one neat volume, royal 12mo., extra cloth, pp. 384. MAGNETISM. IG BLANCHARD & LEA'S MEDICAL GROSS (SAMUEL D.), M. D., Professor of Surgery in the University of Louisville, &c. A PRACTICAL TREATISE ON THE DISEASES, INJURIES, AND MALFORMATIONS OF THE URINARY BLADDER, THE PROSTATE GLAND, AND THE URETHRA. Second Edition, revised and much enlarged, with one hundred and eighty- tour illustrations. In one large and very handsome octavo volume, of over nine hundred pages. (JYow Ready.) The author has availed himself of the opportunity afforded by a call for a new edition of this work, to thoroughly revise and render it in every respect worthy, so far as in his power, of the very flattering reception whicn has been accorded to it by the profession. The new matter thus added amounts to almost one-third of the original work, while the number of illustrations has been nearly doubled. These additions pervade every portion of the work, which thus lias rather the aspect of a new treatise than a new edition. In its present improved form, therefore, it may confidently be presented as a complete and reliable storehouse of information on this important class of diseases, and as in every way fitted to maintain the position which it has acquired in Europe and in this country, as the standard of authority on the subjects treated of. On the appearance of the first edition of this work, I away this reproach ; and so completely has the task the leading English medical review predicted that it ' been fulfilled, that we venture to predict for Dr. would have a " permanent place in the literature of I Gross's treatise a permanent place in the literature surgery worthy to rank with the best works of the of surgery, worthy to rank with the best works of present age." This prediction has been amply ful- the present age. Not merely is the matter good, filled. Dr. Gross's treatise has been found to sup- but the getting up of the volume is most creditable ply completely the want which has been felt ever to transatlantic enterprise; the paper and print since the elevation of surgery to the rank of science, would do credit to a first-rate London establishment ; of a good practical treatise on the diseases of the I and the numerous wood-cuts which illustrate it, de- bladder and its accessory organs. Philos iphical in monstrate that America is making rapid advances in its design, methodical in its arrangement, ample and this department of art. We have, indeed, unfeigned sound in its practical details, it may in truth he said pleasure in congratulating all concerned in this pub- to leave scarcely anything to be desired on so im- lication, on the result of their labours; and expe- portant a subject, and with the additions and modi- rience a feeling something like what animates a long- fications resulting from future discoveries and im- expectant .husbandman, who, oftentimes disappointed provemtnts, it will probably remain one of the most by the produce of a favorite field, is at last agree- valuuble works on this subject so long as the science ably surprised by a stately crop which may bear of medicine shall exist. — Boston Med. and Surg, comparison with any of its former rivals. The Journal, June 7, 1855. : grounds of our high appreciation of the work will A volume replete with truths and principles of the ! &e obvious as we proceed ; and we doubt not that utmost value in the investigation of these diseases.— i the Present facilities for obtaining American books will induce many of our readers to verify our re- commendation by their own perusal of it. — British and Foreign Medico-C hirurgical Review. Whoever will peruse the vast amount of valuable American Medical Journal Dr. Gross has brought all his learning, experi- ence, tact, and judgment to the task, and has pro- duced a work worthy of his high reputation. We feel perfectly safe in recommending it to our read- ers us a monograph unequalled in interest and practical value by any other on the subject in our language. — Western Journal of Med. and Surg. It has remained for an American writer to wipe practical information it contains, and which we have been unable even to notice, will, we think, agree with us, that there is no work in the English language which can make any just pretensions to be its equal. — N. Y. Journal of Medicine. BY THE SAME AUTHOR. (Just Issued). A PRACTICAL TREATISE ON FOREIGN BODIES IN THE AIR-PAS- SAGES. In one handsome octavo volume, with illustrations, pp. 468. A very elaborate work. It is a complete summary a most interesting and hitherto a most neglected de- of the whole subject, and will be a useful book of partment of surgical pathology and practice. — St. reference. — British and Foreign Medico-Chirurg. Louis Med. and Surg. Journal, May, 11555. Keview. Surgical authors, isolated reports in medical pe- A highly valuable book of reference on a most im- riodicals and modern surgeons ' blend their common portant subject in the practice of medicine. We ' toil" to make a book which exhausts the subject, conclude by recommending it to our readers, fully and must forever remain the standard work on the persuaded that its perusal will afford them much management of this accident. — Buffalo Med. J ourn. practical information well conveyed, evidently de- | We consider tnis work one of the most important of the recent additions to practical surgery. Con- taining all that has been recorded relating to the class of accidents of which it treats, admirably arranged and systematized, it should find a place in rived from considerable experience and deduced from an ample collection of facts. — Dublin Quarterly Journal, May, 1855. In this valuable monograph Dr. Gross has cer- tainly struck a new lead in Surgery, and is entitled everyinedical library. — Montreal Med. Chronicle. to the credit of having illustrated and systematized I by the same author. (Preparing.) A SYSTEM OF SURGERY; Diagnostic, Pathological, Therapeutic, and Opera- tive. With very numerous engravings on wood. BY THE SAME AUTHOR. ELEMENTS OF PATHOLOGICAL ANATOMY; illustrated by colored En- gravings, and two hundred and fifty wood-cuts. Second edition, thoroughly revised and greatly enlarged. In one very large and handsome imperial octavo volume, pp. 822. We recommend it as the most complete, and, on The colored engravings and wood-cuts are exceed- the whole, the least defective compilation on the subject in the English language. — Brit, and For. Med. Journal. It is altogether the most complete exposition of Pathological Anatomy in our language. — American Journal of Medical Sciences. if. is the most complete and useful systematic work on Kthological Anatomy in the English language. ingly well executed, and the entire getting up of the work does much credit to the enterprising publishers. We regard it as one of the most valuable works ever issued from the American press, and it does great honor alike to the author, and the country of his birth. — N. Y. Journal of Medicine. We commend it to the attention of the profession as one of the best extant upon the subject on which it treats. — Southern Journal Med. and Pharmacy. AND SCIENTIFIC PUBLICATIONS. 17 GLUGE (GOTTLIEB), M. D., Professor of Physiology and Pathological Anatomy in the University of Brussels, &c. AN ATLAS OF PATHOLOGICAL HISTOLOGY. Translated, with Notes and Additions, by Joseph Leidy, M. D., Professor of Anatomy in the University of Pennsylva- nia. In one volume, very large imperial quarto, with three hundred and twenty figures, plain and colored, on twelve copperplates. This being, as far as we know, the only work in the unconnected observations of a great number of which pathological histology is separately treated authors. The development of the morbid tissues, of in a comprehensive manner, it will, we think, for and the formation of abnormal products, raav now this reason, be of infinite service to those who desire be followed and studied witli the same ease and to investigate the subject systematically, and who satisfaction as the best arranged Bystem of phy- have felt the difficulty of arranging in their mind siology.— American Med. Journal. GARDNER (D. PEREIRA), M . D. MEDICAL CHEMISTRY, for the use of Students and the Profession: being a Manual oi the Science, with its Applications to Toxicology, Physiology, Therapeutics, Hygiene, &c. In one handsome royal 12mo. volume, of about 400 pages, with illustrations. HASSE (C. E.), M. D. AN ANATOMICAL DESCRIPTION OF THE DISEASES OF RESPIRA- TION AND CIRCULATION. Translated and Edited by Swaine. In one volume, octavo. HARRISON (JOHN), M . D. AN ESSAY TOWARDS A CORRECT THEORY OF THE NERVOUS SYSTEM. In one octavo volume, 292 pages. HUNTER (JOHN). TREATISE ON THE VENEREAL DISEASE. With copious Additions, by Dr. Ph. Ricord, Surgeon to the Venereal Hospital of Paris. Edited, with additional Notes, by F. J. Bumstead, M. D. In one octavo volume, with plates (Now Ready.) 1^° See Ricord. Also, HUNTER'S COMPLETE WORKS, with Memoir, Notes, &c. &c. In four neat octavo volumes, with plates. HUGHES (H. M.), M . D., Assistant Physician to Guy's Hospital, &c. A CLINICAL INTRODUCTION TO THE PRACTICE OF AUSCULTA- TION, and other Modes of Physical Diagnosis, in Diseases of the Lungs and Heart. Second American from the Second and Improved London Edition. In one royal 12mo. vol. pp. 304. HORNER (WILLIAM E.), M. D., Professor of Anatomy in the University of Pennsylvania. SPECIAL ANATOMY AND HISTOLOGY. Eighth edition. Extensively revised and modified. In two large octavo volumes, of more than one thousand pages, hand- somely printed, with over three hundred illustrations. This work has enjoyed a thorough and laborious revision on the part of the author, with the view of bringing it fully up to the existing state of knowledge on the subject of general and special anatomy. To adapt it more perfectly to the wants-of the student, he has introduced a large number of additional wood-engravings, illustrative of the objects described, while the publishers have en- deavored to render the mechanical execution of the work worthy of the extended reputation which it has acquired. The demand which has carried it to an EIGHTH EDITION is a sufficient evi- dence of the value of the work, and oi its adaptation to the wants oi the student and professional reader. HOBLYN (RICHARD D.), A. M . A DICTIONARY OF THE TERMS USED IN MEDICINE AND THE COLLATERAL SCIENCES. New and much improved American Edition. Revised, with numerous Additions, from the last London edition, by Isaac Hays, M. D., &c. In one large royal 12mo. volume, of over five hundred pages, double columns. (Now Ready.) In passing this work a second time through the press, the editor has subjected it to a very tho- rough revision, making such additions as the progress of science has rendered desirable, and sup- plying any omissions that may have previously existed. The extent of these addilions may be estimated from the fact that this edition contains about one-third more mailer than the previous one, notwithstanding which it has been kept at the former very moderate rate. As a concise and convenient Dictionary of Medical Terms, at an exceedingly low price, it will therefore be found of great value to the student and practitioner. JONES (T. WHARTON), F. R. S., &c. THE PRINCIPLES AND PRACTICE OF OPHTHALMIC MEDICLNE AND SURGERY. Edited by Isaac Hays, M. D., &c. In one very neat volume, large royal 12mo., of 529 pages, with four plates, plain or colored, and ninety-eight wood-cuis. The work amply sustains, in every point the al- ready high reputation of the author as an ophthalmic surgeon as well as a physiologist and pathologist. The book is evidently the result of much labor and research, and has been written with the greatest care and attention. We entertain little doubt that this book will become what its author hoped it might become, a manual for daily reference and consultation by the student and t lie general practi- tioner. The work is marked by that correctness, clearness, and precision of style which distinguish all the productions of the learned author. — British and Foreign Medical Review. BLANCHARD & LEA'S MEDICAL JONES (C. HANDFIELD), F. R. S., &, EDWARD H. SIEVEKING, M.D., Assistant Physicians and Lecturers in St. Mary's Hospital, London. A MANUAL OF PATHOLOGICAL ANATOMY. First American Edition, Revised. With three hundred and ninety-seven handsome wood engravings. In one large and beautiful octavo volume of nearly seven hundred and fifty pages. (Just Issued.) In a work like the present, intended as a text-book for the student of pathology, accurate engrav- ings of the various results of morbid action are of the greatest assistance. The American pub- lishers have, therefore, considered that the value of the work might be enhanced by increasing the number of illustrations, and, with this object, many wood-cuts, from the best authorities, have been introduced, increasing the number from one hundred and sixty-seven, in the London Edition, to three hundred and ninety-seven in this. The selection of these wood-cuts has been made by a competent member of the profession, who has supervised the progress of the work through the press, with the view of securing an accurate reprint, and of correcting such errors as had escaped the attention of the authors. With these improvements, the volume is therefore presented in the hope of supplying the ac- knowledged want of a work which, within a moderate compass, should embody a condensed and accurate digest of the present state of pathological science, as extended by recent microscopical, chemical, and physiological researches. Asa concise text-book, containing, in a condensed authors have not attempted to intrude new views on form, a complete outline of what is known in the their professional brethren, but simply to lay before domain of Pathological Anatomy, it is perhaps the them, what has long been wanted, an outline of the beat work in the English language. Its great merit present condition of pathological anatomy. In this consists in its completeness and brevity, and in this they have been completely successful. The work is respect it supplies a great desideratum in our lite- one of the best compilations which we have ever rat u re. Heretofore the student of pathology was ' perused. The opinions and discoveries of all the obliged to glean from a great number of monographs, leading pathologists and physiologists are engrossed, and the field was so extensive that but few cultivated bo that by reading any subject treated in the book it with sny degree of success. The authors of the you have a synopsis of the views of the most ap- present work have sought to corrrct this defect by proved authors. — Charleston Medical Journal and placing before the reader a summary of ascertained Review. B^hilSK!llh^ i rfA e ^ l Tiw tte ^^?Jf ,,, ^" ,,t w e have no hesitation in recommending it pathologists both ot the Old and New \\ odd. simple work of reference, therefore, it is value to the student of pathological anato should be in every physician's library.— Western i eminent vve ] mve nn hesitation in recommending it as Id. As a worthy of careful and thorough study by every mem- of great i, er ))f (ne p r<) f eS sion, old, or young. — iV. W. Med. omy, and and Sur? Joltrna i. Lancet, We urge upon our readers and the profession gene- rally the importance of informing themselves in re- gard to modern views of pathology, and recommend to tiiem to procure the work before us as the best means of obtaining this information.— Stethoscope. From the casual examination we have given we are inclined to regard it as a text-book, plain, ra- tional, and intelligible, such a book as the practical man needs for daily reference. For this reason it will be likely to be largely useful, as it suits itself to those busy men who have little time for minute investigation, and prefer a summary to an elaborate in offering the above titled work to the public, the treatise. — Buffalo Medical Journal. KIRKES (WILLIAM SENHOUSE), M . D., Demonstrator of Morbid Anatomy at St. Bartholomew's Hospital, &c.j and JAMES PAGET, F. R. S., Lecturer on General Anatomy and Physiology in St. Bartholomew's Hospital. A MANUAL OF PHYSIOLOGY. Second American, from the second and improved London edition. With one hundred and sixty-five illustrations. In one large and handsome royal 12oio. volume, pp. 5-">0. (Just Issued.) In the present edition, the Manual of Physiology i the practitioner who has but leisure to refresh his has been brought up to the actual condition of the l memory, this book is invaluable, as it contains all science, and fully sustains the reputation which it that it is important to know, without special details, has already so deservedly attained. We consider which are read with interest only by those who the work of MM. Kirkes and Paget to constitute one I would make a specialty, or desire to possessa criti- of the very best handbooks of Physiology we possess ', cal knowledge of the subject. — Charleston Medical — presenting just such an outline of thescienee, coin- | Journal. prising an account of its leading facts and generally \ 0ne of the best treatises that can be put into the admitted principles, as the student requires during hands of the stu dent.— London Medical Gazette. his attendance upon a course of lectures, or for re- | Particularly adapted to those who desire to pos- sess a concise" digest of the facts of Human Physi- ology. — British and Foreign Med.-Chirurg. Review. We conscientiously recommend it as an admira- ble " Handbook of Physiology."— London Journal of Medicine. lor examination. — Am. ference whilst preparing Medical Journal . We need only say, that, without entering into dis- cussions of unsettled questions, it contains all the recent improvements in this department of medical science. For the student beginning this study, and KNAPP (F.), PH. D., &.c. TECHNOLOGY; or, Chemistry applied to the Arts and to Manufactures. Edited, with numerous Notes and Additions, by Dr. Edmund Ronalds and Dr. Thomas Richardson. First American edition, with Notes and Additions, by Prof. Walter R. Johnson. In two hand- some octavo volumes, printed and illustrated in the highest style of art, with about five hundred wood-engraving's. LONGET (F. A.) TREATISE ON PHYSIOLOGY. With numerous Illustrations. Translated from the French by F. G. Smith, M. D., Professor of Institutes of Medicine in the Pennsylvania (Preparing.) Medical Colles LALLEMAND (M.). THE CAUSES, SYMPTOMS, AND TREATMENT OF SPERMATOR- RHCEA. Translated and edited bv Henry J. McDougal. In one volume, octavo, 320 pages. AND SCIENTIFIC PUBLICATIONS. 19 LEHMANN (G. C.) PHYSIOLOGICAL CHEMISTRY. Translated by George E. Day, M. D., and edited by Prof. R. E. Rogers, of the University of Pennsylvania. In two large octavo volumes, with nearly two hundred illustrations. (Now Ready.) This great work, universally recognized as the most complete and authoritative exposition of ita intricate and important subject in its most advanced condition, has received every care during- n* passage through the press, under the superintendence of Prof. Rogers, to insure the entire accuracy indispensable to a work of this character. It has also been improved by the distribution in the appropriate places throughout the text of the numerous additions and corrections embodied in the Appendix, while a number of illustrations have been introduced from "Funke's Atlas of Physiological Chemistry," and an Appendix of Plates has been added. The publishers, therefore, trust that it will he found a complete and accurate edition, and in every respect worthy of the reputation of the work. The progress of research in this department is so and exact view of its present aspect, should lose no rapid, that Prof. Lehmann's treatise must he re- time in attaching themselves to the Society by which garded as having completely superseded that of it is in course of publication. — British and Foreign Simon; and all who desire to possess a systematic , Medico-Chirurgical Review. work on Physiological Chemistry by a man who is T]]e work of Lehmann stands unri valled as the thoroughly qualified, both by his physiological and most comprehensive book of reference and informa- Chemical acquirements, by his own eminence as an tion ext;lnt „„ ny br . inch of ll|t , Bub j ect ,,„ which experimentalist, and by the philosophic impartiality it treats — 2Jrfia6«rg- Monthly Journal of Medical of his habits of thought, to afford a comprehensive Science. by the same author. (Now Ready.) CHEMICAL PHYSIOLOGY. Translated, with numerous additions, by J. Cheston Morris, M. D., with an Introduction by Prof. S. Jackson, of the University of Penn- sylvania, la one handsome octavo volume, with illustrations. The original of this work, though but lately issued by its distinguished author, has already assumed the highest position, as presenting in their latest development the modern doctrines and discoveries in the chemistry of life. The numerous additions by the translator, and the Introduc- tion by Professor Jackson will render its physiological aspect more complete than designed by the author, and will adapt it for use as a text-book of physiology, presenting more thoroughly than has yet been attempled, the modifications arising from the vast impulse which organic chemistry has received within a few years past. LAWRENCE (W.), F. R. S., Sic. A TREATISE ON DISEASES OF THE EYE. A new edition, edited, with numerous additions, and 243 illustrations, by Isaac Hays, M. D., Surgeon to Wills Hospi- tal, &c. In one very large and handsome octavo volume, of'950 pages, strongly bound in leather with raised bands. (Lately Issued.) This work is so universally recognized as the standard authority on the subject, that the pub- lishers in presenting this new edition have only to remark that in its preparation the editor has carefully revised every portion, introducing additions and illustrations wherever the advance of science has rendered them necessary or desirable. The various important contributions to ophthalmological science, recently made by Dalrymple, Jacob, Walton, Wilde, Cooper, &c, both in the form of separate treatises and contributions to periodicals, have been carefully examined by the editor, and, combined with the results of his own experience, have been freely introduced throughout the volume, rendering it a complete and thorough exponent of the most advanced state of the subject. This admirable treatise- the safest guide and most ] octavo pages- has enabled both author and editor to comprehensive work of reference, which is within j do justice to all the details of this subject, and o n- the reach of the profession. — Stethoscope. dense in this single volume the present state of oar This standard text-book on the department of whieh it treats, has not been superseded, by any or all of the numerous publications on the subject heretofore issued. Nor with the multiplied improve- ments of Dr. Hays, the American editor, is it at all likely that this great work will cease to merit the confidence and preference of students or practition- knowledge of the whole science in tltis department, whereby its practical value cannot he excelled. We heartily commend it, especially as a book of refe- rence, indispensable in every medical library. The additions of the American editor very greatly en- hance the value of the work, exhibiting the learning and experience of Dr. Hays, in the light in whieh he ousht to be held, as a standard authority on all sab- - . . .._ :_;_' ... .u: ....;. .It.- M V ATtA C±n~ ers. Its ample extent — nearly one thousand large; jects appertaining to this specialty.— A. Y. Med. Gaz. LEE (ROBERT), M. D., F. R. S., &c. CLINICAL MIDWIFERY; comprising the Histories of Five Huudred and Forty-five Cases of Difficult, Preternatural, and Complicated Labor, with Commentaries. From an edition. In one royal 12mo. volume, extra cloth, of 238 pages. the second London edition. In one royi LUDLOW (J. L.), M. D., Lecturer on Clinical Medicine at the Philadelphia Almshouse, &c. A MANUAL OF EXAMINATIONS upon Anatomy and Physiology, Surgery, Practice of Medicine, Chemistry, Obstetrics, Materia Medica, Pharmacy, and Therapeutics. Designed for Students of Medicine throughout the United States. A new edition, revised and improved. In one large royal 12mo. volume, with several hundred illustrations. (Preparing.) LISTON (ROBERT), F. R. S., &c. LECTURES ON THE OPERATIONS OF SURGERY, and on Diseases and Accidents requiring Operations. Edited, with numerous Additions and Alterations, by T. D. Mutter, M. D. In one large and handsome octavo volume, of 506 pages, with 216 wood-cuts. 20 BLANCHARD & LEA'S MEDICAL LA ROCHE (R.), M . D., &c. PNEUMONIA ; its Supposed Connection, Pathological and Etiological, with Au- tumnal Fevers, including an Inquiry into the Existence and Morbid Agency of Malaria. In one handsome octavo volume, extra cloth, of 500 pages. A more simple, clear, and forcible exposition of I This work should be carefully studied by Southern the groundless nature and dangerous tendency of | physicians, embodying as it does the reflections of certain pathological and etiological heresies, has I an original thinker and close observer on a subject seldom been presented to our notice. — N. Y. Journal peculiarly their own. — Virginia Med. and Surgical 0/ Medicine and Collateral Science. j Journal. by the same author. (Now Ready.) YELLOW FEVER,, considered in its Historical, Pathological, Etiological, and Therapeutical Relations. Including a Sketch of the Disease as it has occurred in Philadelphia from 1699 to 1854, with an examination of the connections between it and the fevers known under the same name in other parts of temperate as well as in tropical regions. In two large and handsome octavo volumes of nearly 1500 pages. The publishers are happy in being able at length to present to the profession this great work, which they are assured will be regarded as an honor to the medical literature of the country. As the result of many years of personal observation and study, as embodying an intelligent resume of all that has been written regarding the disease, and as exhausting 1he subject in all its various aspects, these volumes must at once take the position of the standard authority and work of refe- rence on the many important questions brought into consideration. curate and thorough knowledge of the subject, ac- quired by ample experience and opportunities for investigations both at home and abroad, while he brings to his task peculiar qualifications by his pro- found learning in all that appertains to the science and art of healing. AVe recommend it to the pro- fesaioo and the public as an able and elaborate ri- l ,, "I all that is known on the subject of Yellow Fever, with a vast amount of information upon every aspect of this important topic, upon which the author has expended an amount of industry and renins which can never be adequately rewarded, however appreciated by his brethren. — N. Y. Medi- cal Gazette, October, 1655. From Professor S. J{. Dickson. Charlestcn, S. C, September 18, 1855. A monument of intelligent and well applied re- search, almost without example. It is, indeed, in itself, a large library, and is destined to constitute the special resort as a book of reference, in the subject of which it treats, to all future time. This truly great work has just appeared in two large octavo volumes, and while it will be hailed throughout our country as a must timely and desira- ble contribution to American Medical Literature, it, will be sought for and read with avidity abroad, for its author has a world-wide reputation in scholastic and practical medicine. Dr. La Roche has an ac- LARDNER (DIONYSIUS), D. C. L., &.c. HANDBOOKS OF NATURAL PHILOSOPHY AND ASTRONOMY. Revised, with numerous Additions, by the American editor. First Course, containing Mecha- nics, Hydrostatics, Hydraulics, Pneumatics, Sound, and Optics. In one large royal 12mo. volume, of 750 pages, with -124 wood-cuts. Second Course, containing Heat, Electricity, Mag- netism, and Galvanism, one volume, large royal 12mo., of 450 pages, with 250 illustrations. Third Course ( now ready), containing Meteorology and Astronomy, in one large volume, royal 12mo. of nearly eight hundred pages, with thirty-seven plates and two hundred wood-cuts. The whole complete in three volumes, of about two thousand large pages, with over one thousand figures on steel and wood. Any volume sold separate. The various sciences treated in this work will be found brought thoroughly up to the latest period. MACKENZIE (W.), M.D., Surgeon Oculist in Scotland in ordinary to Her Majesty, &C.&C. A PRACTICAL TREATISE ON DISEASES AND INJURIES OF THE EYE. To which is prefixed an Anatomical Introduction explanatory of a Horizontal Section of the Human Eyeball, by Thomas Wharton Jones, F. R. S. From the Fourth Revised and En- larged London Edition. With Notes and Additions by Addinell Hewson, M.D., Surgeon to Wills Hospital, &c. ccc. In one very large and handsome octavo volume, with plates and numerous wood-cuts. (Now Ready.) The treatise of Dr. Mackenzie indisputably holds 1 accordance with the advances in the science which the first place, and forms, in respect of learning and have been made of late years. Nothing worthy of repetition upon any branch of the subject appears to have escaped the author's notice. We consider it the duty of every one who has the love of his profes- sion and the welfare of his patient at heart, to make himself familiar with this the most complete work in the English language upon the diseases of the eye. — Med. Times and Gazette. The fourth edition of this standard work will no doubt be as fully appreciated as the three former edi- tions. It is unnecessary to say aword in its praise, for the verdict has already been passed upon it by the most competent judges, and " Mackenzie on the Eye" has justly obtained a reputation which it is no figure of speech to call world-wide. — British and Foreign Medico-C 'hirurgical Review. This new edition of Dr. Mackenzie's celebrated treatise on diseases of the eye, is truly a miracle of industry and learning. We need scarcely say that he has entirely exhausted the subject of his specialty. — Dublin Quarterly Journal. research, an Encyclopaedia unequalled in extent by any other work of the kind, either English or foreign. — Dixon on Diseases of the Eye. Few modern books on any department of medicine or surgery have met with such extended circulation, or have procured for their authors a like amount of European celebrity. The immense research which it displayed, the thorough acquaintance with the subject, practically as well as theoretically . and the able manner in which the author's stores of learning and experience were rendered available for general use, at once procured for the first edition, as well on the continent as in this country, that high position as a standard work which each successive edition has more firmly established, in spite of the attrac- tions of several rivals of no mean ability. This, the fourth edition, has been in a great measure re-writ- ten ; new matter, to the extent of one hundred and fifty pages, has been added, and in several instances formerly expressed opinions have been modified in AND SCIENTIFIC PUBLICATIONS. 21 MEIGS (CHARLES D.), M. D., Professor of Obstetrics, &c. in the Jefferson Medical College, Philadelphia. ON THE NATURE, SIGNS, AND TREATMENT OF CHILDBED FEVER. In a Series of Letters addressed to the Students of his Class. In one handsome octavo volume, of three hundred and sixty-five pages. (Now Ready.) The instructive and interesting author of this | This book will add move to his fame than either of those which bear his name. Indeed we doubt whether any material improvement will be made on the teachings of this volume for a century to come, since it is so eminently practical, and based on pro- found knowledge of the science and consummate skill in the art of healing, and ratified by an ample and extensive experience, such as few men have the industry or good fortune to acquire. — N. Y. Med. Gazette. work, whose previous labors in the department of medicine which he so sedulously cultivates, have placed his countrymen under deep and abiding obli- gations, again challenges their admiration in the fresh and vigorous, attractive and racy pages before us. It is a delectable book. * # # This treatise upon child-bed fevers will have an extensive sale, being destined, as it deserves, to find a place in the library of every practitioner who scorns to lag in the rear of his brethren. — Nashville Journal of Medi- cine and Surgery. BY THE SAME AUTHOR. WOMAN : HER DISEASES AND THEIR REMEDIES. A Series of Lec- tures to his Class. Third and Improved edition. In one large and beautifully printed octavo volume. (Just Issued.) pp. 672. The gratifying appreciation of his labors, as evinced by the exhaustion of two large impressions of this work within a tew years, has not been lost upon the author, who has endeavored in every way lo render it worthy of the favor with which it has been received. The opportunity thus afforded for a second revision has been improved, and the work is now presented as in every way superior to its predecessors, additions and alterations having been made whenever the advance of science has rendered them desirable. The typographical execution of the work will also be found to have undergone a similar improvement and the work is now confidently presented as in every way worthy the position it has acquired as the standard American text-book on the Diseases of Females. It contains a vast amount of practical knowledge, by one who has accurately observed and retained the experience of many years, and who tells the re- sult in a free, familiar, and pleasant manner. — Dub- lin Quarterly Journal. There is an off-hand fervor, a glow, and a warm- heartedness infecting the effort of Dr. Meigs, which is entirely captivating, and which absolutely hur- ries the reader through from beginning to end. Be- sides, the book teems with solid instruction, and it shows the very highest evidence of ability, viz., the clearness with which the information is pre- sented. We know of no better test of one's under- standing a subject than the evidence of the power of lucidly explaining it. The most elementary, as well as the obscurest subjects, under the pencil of Prof. Meigs, are isolated and made to stand out in such bold relief, as to produce distinct impressions upon the mind and memory of the reader. — The Charleston Med. Journal. Professor Meigs has enlarged and amended this great work, for such it unquestionably is, having passed the ordeal of criticism at home and abroad, but been improved thereby j for in this new edition the author has introduced real improvements, and increased the value and utility of the book im- measurably. It presents so many novel, bright, and sparkling thoughts; such an exuberance of new ideas on almost every page, that we confess our- selves to have become enamored with the book and its author ; and cannot withhold our congratu- lations from our Philadelphia confreres, that such a teacher is in their service. — N. Y. Med. Gazette. BY THE SAME AUTHOR. OBSTETRICS : THE SCIENCE AND THE ART. Second edition, revised and improved. With one hundred and thirty-one illustrations. In one beautifully printed octavo volume, of seven hundred and fifty-two large pages. (Lately Published.) The rapid demand for a second edition of this work is a sufficient evidence that it has supplied a desideratum of the profession, notwithstanding the numerous treatises on the same subject which have appeared within the last few years. Adopting a system of his own, the author has combined the leading principles of his interesting and difficult subject, with a thorough exposition of its rules of practice, presenting the results of long and extensive experience and of familiar acquaintance with all the modern writers on this department of medicine. As an American Treatise on Mid- wifery, which has at once assumed the position of a classic, it possesses peculiar claims to the at- tention and study of the practitioner and student, while the numerous alterations and revisions which it has undergone in the present edition are shown by the great enlargement of the work, which is not only increased as to the size of the page, but also in the number. BY the same author. (Lately Published.) A TREATISE ON ACUTE AND CHRONIC DISEASES OF THE NECK OF THE UTERUS. With numerous plates, drawn and colored from nature in the highest style of art. In one handsome octavo volume, extra cloth. The object of the author in this work has been to present in a small compass the practical results of his long experience in this important and distressing class of diseases. The great changes intro- duced into practice, and the accessions to our knowledge on the subject, within the last few years, resulting from the use of the metroscope, brings within the ordinary practice of every physician numerous cases which were formerly regarded as incurable, and renders of great value a work like the present combining practical directions for diagnosis and treatment with an ample series of illus- trations, copied accurately from colored drawings made by the author, alter nature. BY THE SAME AUTHOR. OBSERVATIONS ON CERTAIN OF THE DISEASES OF YOUNG CHILDREN. In one handsome octavo volume, of 214 pages. £2 BLANCHARD & LEA'S MEDICAL. MACLISE (JOSEPH), SURGEON. SURGICAL ANATOMY. Forming one volume, very large imperial quarto. With sixty-eight large and splendid Plates, drawn in the best style and beautifully colored. Con- taining- one hundred and ninety Figures, many of them the size of life. Together with copious and explanatory letter-press. Strongly and handsomely bound in extra cloth, being one of the cheapest and best executed Surgical works as yet issued in this country. Copies can be sent by mail, in five parts, done up in stout covers. This great work being now concluded, the publishers confidently present it to the attention of the profession as worthy in every respect of their approbation and patronage. No complete work ot the kind has yet been published in the Engli>h language, and it therefore will supply a want long felt in this country of an accurate and comprehensive Atlas of Surgical Anatomy to which the student and practitioner can at all times refer, to ascertain the exact relative position ol the various portions of the human frame towards each other and to the surface, as well as their abnormal de- viations. The importance of such a work to the student in the absence of anatomical material, and to the practitioner when about attempting an operation, is evident, while the price of the book, not- withstanding the large size, beauty, and finish of the very numerous illustrations, is so low as to place it within the reach of every member of the profession. The publishers therefore confidently anticipate a very extended circulation for this magnificent work. One of the greatest artistic triumphs of the age in Surgical Anatomy. — British American Medical Journal. Too mueh cannot be said in its praise; indeed, we have not language to do it justice. — Ohio Medi- cal and Surgical Journal. The most admirable surgical atlas we have seen. To the practitioner deprived of demonstrative dis- sections upon the human subject, it is an invaluable companion. — N. J. Medical Reporter. The most accurately engraved and beautifully colored plates we have ever seen in an American book — one of the best and cheapest surgical works ever published. — Buffalo Medical Journal. It is very rare that so elegantly printed, so well illustrated, and so useful a work, is offered at so moderate a price. — Charleston Medical Journal. Its plates can boast a superiority which places them almost beyond the reach of competition. — Midi- cat Examiner. Every practitioner, we think, should have a work of this kind within reach. — Southern Medical and Surgical Journal. No such lithographic illustrations of surgical re- gions have hitherto, we think, been given. — Boston Medical and Surgical Journal. As a surgical anatomist, Mr. Maclise has proba- bly no superior. — British and Foreign Medico-Chi- rurgical Review. Of great value to the student engaged in dissect- ing, and to the surgeon at a distance from the means of keeping up his anatomical knowledge. — Medical Times. The mechanical execution cannot be excelled. — Transylvania Medical Journal. A work which has no parallel in point of accu- racy and cheapness in the English language. — iV. Y. Journal of Medicine. To all engaged in the study or practice of their profession, such a work is almost indispensable. — Dublin Quarterly Medical Journal. No practitioner whose means will admit should fail to possess it. — hanking's Abstract. Country practitioners will find these plates of im- mense value. — N. Y. Medical Gazette. We are extremely gratified to announce to the profession the completion of tins truly magnificent work, which, as a whole, certainly stands unri- valled, both for accuracy of drawing, beauty of coloring, and all the requisite explanations of the subject in hand. — The New Orleans Medical and Surgical Journal. This is by far the ablest work on Surgical Ana- tomy that has come under our observation. We know of no other work that would justify a stu- dent, in any degree, for neglect of actual dissec- tion. In those sudden emergencies that so often arise, and which require the instantaneous command of minute anatomical knowledge, a work of this kind keeps the details of the dissecting-room perpetually fresh in the memory — The Western Journal of Medi- cine and Surgery. fi^ST 1 The very low price at which this work is furnished, and the beauty of its execution, require an extended sale to compensate the publishers tor the heavy expenses incurred. MULLER (PROFESSOR J.), M.D. PRINCIPLES OF PHYSICS AND METEOROLOGY. Edited, with Addi- tions, by 11. Eglesfeld Griffith, M. D. In one large and handsome octavo volume, extra cloth, with 550 wood-cuts, and two colored plates, pp. 636. The Physics of MQller is a work superb, complete, | tion to the scientific records of this country may be unique : tiie greatest want known to English Science | duly estimated by the fact that, the cost of the origi- coufd not have been better supplied. The work is I nal drawings and engravings alone liaE exceeded the of surpassing interest. The value of this contribu- | sum of £2,000. — Lancet. MAYNE (JOHN), M . D., M . R. C. S. A DISPENSATORY AND THERAPEUTICAL REMEMBRANCER. Cora- prising the entire lists of Materia Medica, with every Practical Formula contained in the three British Pharmacopoeias. With relative Tables subjoined, illustrating, by upwards of six hundred and sixty examples, the Extemporaneous Forms and Combinations suitable for the different Medicines. Edited, with the addition of the Formulae of the United States Pharmacopoeia, by R. Eglesfeld Griffith, M. D. In one 12mo. volume, extra cloth, of over 300 large pages. MATTEUCCI (CARLO). LECTURES ON THE PHYSICAL PHENOMENA OF LIVING BEINGS. Edited by J. Pereira, M. D. In one neat royal 12mo. volume, extra cloth, with cuts, 388 pages. AND SCIENTIFIC PUBLICATIONS. 23 MILLER (JAMES), F. R. S. E., Professor of Surgery in the University of Edinburgh, &c. PRINCIPLES OF SURGERY. A new American, from the third and revised Edinburgh edition. In one large and very beautiful volume, of about seven hundred pages, with two hundred and forty exquisite illustrations on wood. 'Novj Ready.) This edition is far superior, both in the abundance and quality of its material, to any of the preceding. We hope it will be extensively read, and the sound principles which are herein taught treasured up for future application. The work takes rank with Watson's Practice of Physic; it certainly does not fall behind that great work in soundness of princi- ple or depth of reasoning and research. No physi- cian who values his reputation,^or seeks the interests of his clients, can acquit himself before his God and the world without making himself familiar with the sound and philosophical views developed in the fore- going book. — New Orleans Med. and Surg. Journal. Without doubt the ablest exposition of the prin- ciples of that branch of the healing art in any lan- guage. This opinion, deliberately formed after a careful study of the first edition, we have had no cause to change on examining the second. This edition has undergone thorough revision by the au- thor ; many expressions have been modified, and a mass of new matter introduced. The hook is got up in the finest style, and is an evidence of the progress of typography in our country. — Charleston Medical Journal and Review. We recommend it to both student and practitioner, feeling assured that as it now comes to us, it pre- sents the most satisfactory exposition of the modern doctrines of the principles of surgery to be found in any volume in any language. — N.' Y. Journal of Medicine. BY the same author. (Lately Published.) THE PRACTICE OF SURGERY. Third American from the second Edin- burgh edition. Edited, with Additions, by F. W. Sargent, M. D , one of the Surgeons to Will's Hospital, cV*c Illustrated by- three hundred and nineteen engravings on wood. In one large octavo volume, of over seven hundred pages. No encomium of ours could add to the popularity of Miller's Surgery. Its reputation in this country is unsurpassed by that of any other work, and, when taken in connection with the author's Principles of Surgery, constitutes a whole, without reference to which no conscientious surgeon would be willing to practice his art The additions, by Dr. Sargent, have materially enhanced the value of the work. — Southern Medical and Surgical Journal. It is seldom that two volumes have ever made so profound an impression in so short a time as the " Principles" and the " Practice" of Surgery by Mr. Miller — or so richly merited the reputation they have acquired. The author is an eminently sensi- ble, practical, and well-informed man, who knows exactly what he is talking about and exactly how to talk it. — Kentucky Medical Recorder. The two volumes together form a complete expose of the present state of Surgery, and they ought to be on the shelves of every surgeon. — N. J. Med. Re- porter. By the almost unanimous voice of the profession, his works, both on the principles and practice of surgery have been assigned the highest rank. If we were limited to but one work on surgery, that one should be Miller's, as we regard it as superior to all others. — St. Louis Med. and Surg. Journal. The author distinguished alike as a practitioner and writer, has in this and his il Principles," pre- sented to the profession one of the most completeand reliable systems of Surgery extant. His style of writing is original, impressive, and engaging, ener- getic, concise, and lucid. Few have the faculty of condensing so much in small space, and at the same time so persistently holding the attention; indeed, he appears to make the very process of condensation a means of eliminating attractions. Whether as a text-book for students or a book of reference for practitioners, it cannot be too strongly recommend- ed. — Southern Journal of the Medical and Physical Sciences. MALGAIGNE (J. F.). OPERATIVE SURGERY, based on Normal and Pathological Anatomy. Trans- lated from the French, by Frederick Brittan, A. B., M. D. With numerous illustrations on wood. In one handsome octavo volume, of nearly six hundred pages. MOHR (FRANCIS) PH.D., AND RED WOO D (TH EOPH I LUS). PRACTICAL PHARMACY. Comprising the Arrangements, Apparatus, and Manipulations of the Pharmaceutical Shop and Laboratory. Exiled, with extensive Additions, by Prof. William Procter, of the Philadelphia College of Pharmacy. In one handsomely printed octavo volume, of 570 pages, with over 500 engravings on wood. NEILL (JOHN), M. D., Professor of Surgery in the Pennsylvania Medical College, &c. OUTLINES OF THE ARTERIES. With short Descriptions. Designed for the Use of Medical Students. With handsome colored plates. Second and improved edition. In one octavo volume, extra cloth. OUTLINES OF THE NERVES. With short Descriptions. Designed for the Use of Medical Students. With handsome plates. Second and improved edition. In one octavo volume, extra cloth. OUTLINES OF THE VEINS AND LYMPHATICS. With short Descrip- tions. Designed for the Use of Medical Students. With handsome colored plates. In one octavo volume, extra cloth. ALSO — The three works done up in one handsome volume, half bound, with numerous plates, pre- senting a complete view of the Circulatory, Nervous, and Lymphatic Systems. This book should be in the hand of every medical Btudent. It is cheap, portable, and precisely the thing needed in studying an important, though diffi- cult part of Anatomy. — Boston Med. and Surg. Journal. We recommend every student of medicine to pur- chase a copy of this work, as a labor-saving ma- chine, admirably adapted to refresh the memory, with knowledge gained by lectures, dissections, and the reading of larger works. — N. Y. Journal of Medicine. This work is from the pen of a Philadelphia ana- tomist, whose familiar knowledge of the subject has been aided by the press, the result of which is a vo- lume of great beauty and excellence. Its fine exe- cution commends it to the siudent of Anatomy. It requires no other recommendations. — Western Jvurn. of Medicine and Surgery. 24 BLANCHARD & LEA'S MEDICAL NEILL (JOHN), M. D., Surgeon to the Pennsylvania Hospital , &c .; and FRANCIS GURNEY SMITH, M. D., Professor of Institutes of Medicine in the Pennsylvania Medical College. AN ANALYTICAL COMPENDIUM OF THE VARIOUS BRANCHES OF MEDICAL SCIENCE ; for the Use and Examination of Students. A new edition, revised and improved. In one very large and handsomely printed royal 12mo. volume, of about one thousand pages, with three hundred and seventy-four illustrations on wood. Strongly bound in leather, with raised bands. [Now Ready.) The speedy sale of a large impression of this work has afforded to the authors gratifying evidence of the correctness of the views which actuated Ihem in its preparation. In meeting the demand for a second edition, they have therefore been desirous to render it more worthy of the favor with which it has been received. To accomplish this, they have spared neither time nor labor in embo- dying in it such discoveries and improvements as have been made since its first appearance, and such alterations as have been suggested by its practical use in the class and examination-room. Considerable modifications have thus been introduced throughout all the departments treated of in the volume, but more especially in the portion devoted to the "Practice of Medicine," which has been entirely rearranged and rewritten. Notwithstanding the enlarged size and improved execution of this work, the price has not been increased, and it is confidently presented as one of the cheapest volumes now before the profession. Having made free use of this volume in our ex- aminations of pupils, we can speak from experi- ence in recommending it as an admirable compend for students, and as especially useful to preceptors who examine their pupils. It will save the teacher much labor by enabling him readily to recall all of the points upon which his pupils should be ex- amined. A work of this sort should be in the hands of every one who takes pupils into his office with a view of examining them; and this is unquestionably the bestof its class. Let every practitioner who has pupils provide himself with it, and he will find the labor of refreshing his knowledge so much facilitated that he will be able to do justice to his pupils at very little cost of time or trouble to himself. — Transyl- vania Med. Journal. In the rapid course of lectures, where work for the students is heavy, and review necessary for an examination, a compend is not only valuable, but it is almost a sine qua non. The one before us is, in most of the divisions, the most unexceptionable of all books of the kind that we know of. The newest and soundest doctrines and the latest im- provements and discoveries are explicitly, though concisely, laid before the student. Of course it is useless for us to recommend it to all last course students, but there is a class to whom we very sincerely commend this cheap book as worth its weight in silver — that class is the graduates in medicine of more than ten years' standing, who have not studied medicine since. They will perhaps find out from it that the science is not exactly now what it was when they left it off. — The Stethoscope NELIGAN (J. MOORE), M. D., M. R. I. A., &c. A PRACTICAL TREATISE ON DISEASES OF THE SKIN. In one neat royal 12mo. volume, of 334 pages. BY THE SAME AUTHOR. (JllSt Ready.) ATLAS OF CUTANEOUS DISEASES. In one beautiful quarto volume, with splendid Colored plates, presenting nearly one hundred elaborate representations of disease. This beautiful volume is intended to accompany the author's " Treatise on Diseases of the Skin," so favorably received by the profession some vears since. In the description of the plates, reference is made to the chapter and page of the " Treatise," so that together the two constitute, at a much smaller cost than has been hitherto attempted, a complete work of reference for the Diagnosis and Treatment of this difficult class of diseases, which, more than any other, perhaps, require this mode of pictorial elucidation. Dr. Neligan deserves our best thanks for this i ence to the chapter of that work where the disease attempt to supply a want which has been long felt, j receives special mention. Great care has evidently For a small sum he here presents us with an Atlas , been taken to procure proper subjects for the artist containing some ninety plates of the more com- and the daguerreotype, which has been employed in mon and rarer forms of affections of the skin, and ; several of the plates, " to secure correctness in the for the benefit of those who possess his useful I design." — Edinburgh Medical Journal, September, Manual, he supplies with each illustration a refer- | 1855. OWEN (PROF. R.), Author of" Lectures on Comparative Anatomy," " Archetype of the Skeleton," &c. ON THE DIFFERENT FORMS OF THE SKELETON, AND OF THE TEETH. One vol. royal 12mo., with numerous illustrations. (Just Issued.) PANCOAST (J.), M. D., Professor of Anatomy in the Jefferson Medical College, Philadelphia, ice. OPERATIVE SURGERY; or, A Description and Demonstration of the various Processes of the Art ; including all the New Operations, and exhibiting the State of Surgical Science in its present advanced condition. Complete in one royal 4lo. volume, of 380 pages of letter-press description and eighty large 4to. plates, comprising 486 illustrations. Second edition, improved. This excellent work is constructed on the model cerned, we are proud as an American to say that, of the French Surgical Works by Velpeau and Mai- of its kixd it has no superior. — N. Y. Journal of gaigne; and, so far as the English language is con- Medicine. PARKER (LANGSTON), Surgeon to the Queen's Hospital, Birmingham. THE MODERN TREATMENT OF SYPHILITIC DISEASES, BOTH PRI- MARY" AND SECONDARY; comprising the Treatment of Constitutional and Confirmed Syphi- lis, by a safe and successful method. With numerous Cases, Formulfe, and Clinical Observa- tions. From the Third and entirely rewritten London edition. In one neat octavo volume, AND SCIENTIFIC PUBLICATIONS. 25 (Noiv Complete.) PEREIRA (JONATHAN), M. D., F. R. S., AND L. S. THE ELEMENTS OF MATERIA MEDICA AND THERAPEUTICS. Third American edition, enlarged and improved by the author; including Notices of most of the Medicinal Substances in use in the civilized world, and forming an Encyclopaedia of Materia Medica. Edited, with Additions, by Joseph Carson, M. D., Professor of Materia Medica and Pharmacy in the University of Pennsylvania. In two very large octavo volumes of 2100 pages, on small type, with over four hundred and fifty illustrations. Volume I. — Lately issued, containing the Inorganic Materia Medica, over 800 pages, with 145 illustrations. Volume II. — Now ready, embraces the Organic Materia Medica, and forms a very large octavo volume of 1250 pages, with two plates and three hundred handsome wood-cuts. The present edition of this valuable and standard work will enhance in every respect its well- deserved reputation. The care bestowed upon its revision by the author may be estimated by the fact that its size has been increased by about five hundred pages. These additions have extended to every portion of the work, and embrace not only the materials afforded by the recent editions of the pharmacopoeias, but also all the important information accessible to the care and industry of the author in treatises, essays, memoirs, monographs, and from correspondents in various parts of the globe. In this manner the work comprises the most recent and reliable information respecting all the articles of the Materia Medica, their natural and commercial history, chemical and thera- peutical properties, preparation, uses, doses, and modes of administration, brought up to the present lime, with a completeness not to be met with elsewhere. A considerable portion of the work which preceded the remainder in London, has also enjoyed the advantage of a further revision by the author expressly for this country, and in addition to this the editor, Professor Carson, has made whatever additions appeared desirable to adapt it thoroughly to the U. S. Pharmacopoeia, and to the wants of the American profession. An equal improvement will likewise be observable in every department of its mechanical execution. It is printed from new type, on good white paper, with a greatly extended and improved series of illustrations. Gentlemen who have the first volume are recommended to complete their copies without delay. The first volume will no longer be sold separate. When we remember that Philology, Natural His- [ Medica, although completed under the supervision of tory, Botany, Chemistry, Physics, anil the Micro- I others, is by far the most elaborate treatise in the scope, are all brought forward to elucidate the sub- | English language, and will, while medical literature ject, one cannot fail to see that the reader has here , is cherished, continue a monument alike honorable a work worthy of the name of an encyclopedia of j to his genius, as to his learning and industry. — Materia Medica. Our own opinion of its merits is that of its editors, and also that of the whole profes- sion, both of this and foreign countries— namely, '• that in copiousness of details, in extent, variety, and accuracy of information, and in lucid explana- tion of difficult and recondite subjects, it surpasses all other works on Materia Medica hitherto pub- lished." We cannot close this notice without allud- ing to the special additions of the American editor, which pertain to the prominent vegetable produc- tions of this country, and to the directions of the United States Pharmacopoeia, in connection with all the articles contained in the volume which are re- ferred toby it. The illustrations have been increased, and this edition by Dr. Carson cannot well be re- garded in any other light than that of a treasure which should be found in the library of every physi- cian. — New York Journal of Medical and Collateral Science, March, 1854. The third edition of his "Elements of Materia American Journal of Pharmacy, March, 1854. The work, in its present shape, and so far as can be judged from the portion before the public, forms the most comprehensive and complete treatise on materia medica extant in the English language. — Dr. Pereira has been at great pains to introduce into his work, not only all the information on the natural, chemical, and commercial history of medi- cines, which might be serviceable to the physician and surgeon, but whatever might enable his read- ers to understand thoroughly the mode of prepar- ing and manufacturing various articles employed either for preparing medicines, or for certain pur- poses in the arts connected with materia medica and the practice of medicine. The accounts of the physiological and therapeutic effects of remedies are given with great clearness and accuracy, and in a manner calculated to interest as well as instruct the reader. — The Edinburgh Medical and Surgical Journal. PEASLEE (E. R.), M. D., Professor of Anatomy and Physiology in Dartmouth College, &c. HUMAN HISTOLOGY, in its applications to Physiology and General Pathology; designed as a Text-Book for Medical Students. With numerous illustrations. In one handsome royal 12mo. volume. [Preparing.) The subject of this work is one, the growing importance of which, as the basis of Anatomy and Physiology, demands for it a separate volume. The book will therefore supply an acknowledged deficiencyin medical text-books, while the name of the author, and his experience as a teacher for the las.t thirteen years, is a guarantee that it will be thoroughly adapted to the use of the student. P1RRIE (WILLIAM), F. R. S. E., Professor of Surgery in the University of Aberdeen. THE PRINCIPLES AND PRACTICE OF SURGERY. Edited by John Neill, M. D., Professor of Surgery in the Penna. Medical College, Surgeon to the Pennsylvania Hospital, &c. In one very handsome octavo volume, of 780 pages, with 316 illustrations. We know of no other surgical work of a reason- able size, wherein there is so much theory and prac- tice, or where subjects are more soundly or clearly taught. — The Stethoscope. There is scarcely a disease of the bone or soft rmrts, fracture, or dislocation, that is not illustrated by accurate wood-engravings. Then, again, every instrument employed by the surgeon is thus repre- sented. These engravings are not only correct, but really beautiful, showing the astonishing degree of perfection to which the art of wood-engraving has arrived. Prof. Pirrie, in the work before us, has elaborately discussed the principles of surgery, and a safe and effectual practice predicated upon them. Perhaps no work upon this subject heretofore issued is so full upon the science of the art of surgery. — Nashville Journal of Medicine and Surgery. One of the best treatises on surgery in the English language. — Canada Med. Journal. Our impression is, that, as a manual for students, Pirrie's is the best work extant. — Western Med. and Surg. Journal. 26 BLANCHARD & LEA'S MEDICAL PARRISH (EDWARD), Lecturer on Practical Pharmacy and Materia Medica in the Pennsylvania Academy of Medicine, &c. A PRACTICAL INTRODUCTION TO PHARMACY. Designed as a Text- Book for the Student, and as a Guide to the Physician and Pharmaceutist. With numerous Formulae and over 200 Illustrations. In one handsome octavo volume. (Now Ready.) The want of an elementary textbook on this subject has long- been felt and acknowledged While vast stores of information on all the collateral brandies of pharmacy are contained in such works as Mohr and Redwood, the U. S. Dispensatory, the Pharmacopoeia, Pereira, and others, there has been no compendious manual presenting wiihin a moderate compass, and in systematic order, the innumerable minor details which make up the everyday business of those who dispense medicines. It has been the object of the author to supply this want, and while to the pharmaceutist such a work is manifestly indispensable, its utility will hardly be less to the country practitioner, residing at a distance from drug stores, and obliged to dispense the remedies which he prescribes. Familiarized with the elements of therapeutics and the essentials of materia medica, by his at- tendance at lectures, he has hitherto been obliged to learn for himself the details of prescribing, compounding, and preparing medicines. The volume commences with a chapter on the "outfit" of the country physician, describing the different articles, their various kinds and comparative ad- vantages; the Pharmacopoeia is described, explained, and commented upon, its contents classified and arranged so as to be easily comprehended and referred to; all the operations of pharmacy are given in minute detail, and under each head the various preparations are specified to which it is applicable, with directions for making them, giving in this manner a comprehensive and practical view of the materia medica, with much valuable information regarding all the more important ar- ticles. All the officinal formulae are thus presented, with directions for their preparation and use, together with many empirical ones of interest, and numerous new ones derived from the praclice of distinguished physicians. Especial attention lias been bestowed on the new remedies, the more important of which are minutely described, particularly those derived from our indigenous plants, which have of late attracted so much attention, and which the author has thoroughly investigated. The chapters on extemporaneous pharmacy contain clear and accurate instructions for writing prescriptions, selecting, combining, dispensing, and compounding medicines, making powders, piils, mixtures, ointments, &c. &c, with formulae; and the work concludes with an ap- pendix of valuable hints and advice to those purchasing articles connected with their profession. Numerous tables interspersed throughout elucidate the various subjects, which are rendered still clearer by a large number of engravings. Care lias been taken in all instances to indicate and describe the simplest apparatus and procedures affording satisfactory results. The long experience of the author, both as a teacher of pharmacy, and as a practical pharmaceutist, is BUfficienl guarantee of his familiarity with the wants and necessities of the student, and of his ability to satisfy them. ROKITANSKY (CARD, M.D., Curator of the Imperial Pathological Museum, and Professor at the University of Vienna, Ice. A MANUAL OF PATHOLOGICAL ANATOMY. Four volumes octavo, bound in two. (Now Ready.) Vol. I. — Manual of General Pathological Anatomy. Translated by W. E. Swaine. Vol. II.— Pathological Anatomy of the Abdominal Viscera. Translated by Edward Sieveking, M. D. Vol. III. — Pathological Anatomy of the Bones, Cartilages, Muscles, and Skin, Cellular and Fibrous Tissue, Serous and Mucous Membrane, and Nervous System. Translated by C. H. Moore. Vol. IV. — Pathological Anatomy of the Organs of Respiration and Circulation. Translated bv G. E. Day. To render this large and important work more easy of reference, and at the same time less cum- brous and costly, the publishers have arranged the four volumes in two, retaining, however, the separate paging, &c. The publishers feel much pleasure in presenting to the profession of the United States the great work of Prof. Rokitansky, which is universally referred to as the standard of authority by the pa- thologists of all nations. Under the auspices of the Sydenham Society of London, the combined labor of four translators has at length overcome the almost insuperable difficulties which have so long prevented the appearance of the work in an English dress, while the additions made from various papers and essays of the author present his views on all the topics embraced, in their latest published form. To a work so widely known, eulogy is unnecessary, and the publishers would merely slate that it contains the results of not less than thirty thousand post-morte.m examina- tions made by 1 he author, diligently compared, generalized, and wrought into one complete and harmonious system. R1GBY (EDWARD), M.D., Physician to the General Lying-in Hospital, &e. A SYSTEM OF MIDWIFERY. With Notes and Additional Illustrations. Second American Edition. One volume octavo, 422 pages. ROYLE (J. FORBES), M. D. MATERIA MEDICA AND THERAPEUTICS; including the Preparations of the Pharmacopoeias of London, Edinburgh, Dublin, and of the United States. With many new medicines. Edited by Joseph Carson, M. D., Professor of Materia Medica and Pharmacy in the University of Pennsylvania. With ninety-eight illustrations. In one large octavo volume, of about seven hundred pages. This work is, indeed, a most valuable one, and will fill up an important vacancy that existed be- tween Dr. Pereira's most learned and complete system of Materia Medica, and the class of pro- ductions on the other extreme, which are neces- sarily imperfect from their small extent. — British and Foreign Medical Review. AND SCIENTIFIC PUBLICATIONS. 27 RAMSBOTHAM (FRANCIS H.), M.D. THE PRINCIPLES AND PRACTICE OF OBSTETRIC MEDICINE AND SURGERY, in reference to the Process of Parturition. A new and enlarged edition, thoroughly revised by the Author. With Additions by W. V. Keating, M. D. In one large and handsome imperial oclavo volume, of 650 pages, with sixty-four beautiful Plates, and numerous Wood-cuts in the text, containing in all nearly two hundred large and beautiful figures. (Now Ready.) In calling the attention of the profession to the new edition of this standard work, the publishers would remark that no efforts have been spared to secure for it a continuance and extension of the remarkable favor with which it has been received. The last London issue, which was considera- bly enlarged, has received a further revision from the author, especially for this country. Its pas- sage through the press here has been supervised by Dr. Keating, who has made numerous addi- tions with a view of presenting more fully whatever was necessary to adapt it thoroughly to American modes of practice. In its mechanical execution, a like superiority over former editions will be found. The plates have all been re-engraved in a new and beautiful style ; many additional illustrations have been introduced, and in every point of typographical finish it will be found one of the handsomest issues of the American press. In its present improved and enlarged form the pub- lishers therefore confidently ask for it a place in every medical library, as a text-book for the student, or a manual for daily reference by the practitioner. From Prof. Hodge, of the University of Pa. To the American public, it is most valuable, from its intrinsic undoubted excellence, and as being the best authorized exponent of British Midwifery. Its circulation will, I trust, be extensive throughout our country. The publishers have shown their appreciation of ; cine and Surgery to our library, and confidently the merits of this work and secured its success by recommend it to our readers, with the assurance the truly elegant style in which they have brought that it will not disappoint their most sanguine ex- it out, excelling themselves in its production, espe- I pectations. — Western Lancet. cially in its plates. It is dedicated to Prof. Meigs, and has the emphatic endorsement of Prof. Hodge, as the best exponent of British Midwifery. Wc know of no text-book which deserves in all respects to be more highly recommended to studeuts, and we could wish to see it in the hands of every practitioner, for they will find it invaluable for reference. — Med. Gazette. It is unnecessary to say anything in regard to the utility of this work. It is already appreciated in our country for the value of the matter, the clearness of its style, and the fulness of its illustrations. To the physician's library it is indispensable, while to the student as a text-book, from which to extract the material for laying the foundation of an education on obstetrical science, it has no superior. — Ohio Med. and Surg. Journal. We will only add that the student will learn from it all he need to know, and the practitioner will find But once in a long time some brilliant genius rears bis head above the horizon of science, and illumi- nates and purifies every department that he investi- gates ; and his works become types, by which innu- . merable imitators model their feeble productions, it- as a book of reference, surpassed by none other.— Such a genius we lind in the younger Ramsbotham, Stethoscope. and such a type we find in the work now before us. The character and merits of Dr. Ramsbothara's The binding, p;'per, type, the engravings and wood- t work are so well known and thoroughly established, cuts are all so excellent as to make this book one of i that comment is unnecessary and praise superfluous, the finest specimens of the art of printing that have The illustrations, which are numerous and accurate, given such a world-wide reputation to its cnterpri- j are executed in the highest style of art. We cannot sins' and liberal publishers. We welcome Rams- ! too highly recommend the work to our readers. — St. boiham's Principles and Practice of Obstetric Medi- i Louis Med. and Surg. Journal. RICORD (P.), M. D., Surgeon to the Hopital du Midi, Paris, ice. ILLUSTRATIONS OF SYPHILITIC DISEASE. Translated from the French, by Thomas F. Betton, M. D. With the addition of a History of Syphilis, and a complete Bib- liography and Formulary of Remedies, collated and arranged, by Paul B. Goddard, M. D. With fifty large quarto plates, comprising one hundred and seventeen beautifully colored illustrations, hi one large and handsome quarto volume. by the same author. (Lately Publislted.) A TREATISE ON THE VENEREAL DISEASE. By John Hunter, F. R. S. With copious Additions, by Ph. Ricord, M. D. Edited, with Notes, by Freeman J. Bumstead, M. D. In one handsome octavo volume, of 520 pages, with plates. Kvery one will recognize the attractiveness and value which this work derives from thus presenting the opinions of these two masters side by side. But, K must be admitted, what has made tiie fortune of the book, is i lie fact that it contains the "most com- plete embodiment of the veritable doctrines of the Hopital du Midi," which has ever been made public. The doctrinal ideas of M. Ricord, ideas which, if not universally adopted, are incontestably dominant, have heretofore only been interpreted by more or less skilful secretaries, sometimes accredited and sometimes not. In the notes to Hunter, the mister substitutes him- selfforhis interpreters, and gives his original thoughts to the world, in a summary form it is true, but in a lucid and perfectly intelligible manner. In eonclu sion we can say that this is incontestably the best treatise on syphilis with which wc are acquainted, and, as we do not often employ the phrase, we may be excused for expressing the hope that it may find a place in the library of every physician — Virginia Med. and Stcrg. Journal. BY THE SAME AUTHOR. LETTERS ON SYPHILIS, addressed to the Chief Editor of the Union Medieale. With an Introduction, by Amedee Latour. Translated by \V. P. Laltimore, M. D. In one neat octavo volume of 270 pages. » BY THE SAME AUTHOR. A PRACTICAL TREATISE ON VENEREAL DISEASES. With a Thcra- peutical Summary and Special Formulary. Translated by Sidney Doane, M. D. Fourth edition. One volume, octavo, ,110 pages. 28 BLANCHARD & LEA'S "MEDICAL SMITH (HENRY H.), Professor of Surgery in the University of I enns t vania, &c. MINOR SURGERY; or, Hints on the E very-day Duties of the Surgeon. Illus- trated by two hundred and forty-seven illustrations. Third and enlarged edition. In one hand- some royal 12mo. volume, pp. 456. And a capital little book it is. . . Minor Surgery, we repeat, is really Major Surgery, and anything which teaches it is worth having. So we cordially recommend this little book of Dr. Smith's.— Med.- Chir. Review, A work such as the present is therefore highly useful to the student, and we commend this one to their attention. — American Journal of Medical Sciences. No operator, however eminent, need hesitate to consult this unpretending yet excellent book. Those who are young in the business would find Dr. Smith's treatise a necessary companion, after once under- standing its true character. — Boston Me J. and Surg. Journal. This beautiful little work has been compiled with a view to the wants of the profession in the matter of bandaging, &c.,and well and ably has the author performed his labors. Well adapted to give the requisite information on the subjects of which it treats. — Medical Examiner. The directions are plain, and illustrated through- out with clear engravings. — London Lancet. One of the best works they can consult on the subject of which it treats. — Southern Journal of Medicine and Pharmacy. BY THE SAME AUTHOR, AND HORNER (WILLIAM E.) f M. D., Late Professor of Anatomy in the University of Pennsylvania. AN ANATOMICAL ATLAS, illustrative of the Structure of the Human Body. In one volume, large imperial octavo, with about six hundred and fifty beautiful figures. These figures are well selected, and present a late the student upon the completion of this Atlas, No young practitioner should be without this little volume; and we venture to assert, that it maybe consulted by the senior members of the profession with more real benefit, than the more voluminous works. — Western Lancet. complete and accurate representation of that won- derful fabric, the human body. The plan of this Atlas, which renders it so peculiarly convenient for the student, and its superb artistical execution, have been already pointed out. We must eongrato- as it is the most convenient work of the kind that has yet appeared ; and we must add, the very beau- tiful manner in which it is ■' got up - ' is so creditable to the country as to be flattering to our national pride. — American Medical Journal. SARGENT iF. W.), M. D. ON BANDAGING AND OTHEi; OPERATIONS OF MINOR SURGERY. Second edition, enlarged. One handsome royal L2mo. vol., of nearly 400 pages, with 182 wood-cuts. {Now Ready.) The very best manual of Minor Surgery we have seen; an American volume, with nearly four hundred pages of good practical lessons, illustrated by about one hundred and thirty wood-cuts. In thes^ days of "trial," when a doctor's reputation hangs upon a clove hitch, or the roll of a bandage, it Would he well, perhaps, to carry such a volume as Air We have carefully examined this work, and find it well executed and admirably adapted to the use of the student. Besides the subjects usually embraced in works on Minor Surgery, there is a short chapter on bathing, another on anaesthetic agents, and an appendix of formulae. The author has given an ex- cellent work on this subject, and Ins publishers have gent's always in our coat-pocket, or, at all i vents, illustrated and printed it in most beautiful style. — to listen attentively to his instructions at home — The Charleston Medical Journal. Buffalo Med. Journal. SKEY (FREDERICK C), F. R. S., &c. OPERATIVE SURGERY. In om very handsome octavo volume of over 650 pages, with about one hundred wood-cut> SHARPEY (WILLIAM), rV >., JONES QUAIN, M.D., AND RICHARD QUAIN, F. R. S., &c. HUMAN ANATOMY. Revised, with Notes and Additions, by Joseph Leidy, M. D. Complete in two large octavo volumes, of about thirteen hundred pages. Beautifully illustrated with over five hundred engra\ ings on wood. We have no hesitation in recommending this trea- tise on anatomy as the most complete on that sub- ject in the English language ; and the only one, perhaps, in any language, which brings the state of knowledge forward to the most recent disco- veries. — The Edinburgh Med. and Surg. Journal. Admirably calculated to fulfil the object for which it is intended. — Provincial Medical Journal. It is indeed a work calculated to make an in anatomical study, by placing before the student every department of his science, with a view to the relative importance of each ; and so skilfully have the different parts been interwoven, n i no one who makes this work the basis of his studies, will hereafter have any excuse for neglecting ir undervaluing any important particulars coin.'" ed with the structure of the human frame, nd whether the bias of his mind lead him in a ml re especial manner to surgery, physic, or physiology, he will find here a work at once so compreli isive and practical as to defend him from exclusi on the one hand, and pedantry on the 01 Journal and Retrospect of the Medical S ' The most complete Treatise on Anatomy in the English language. — Edinburgh Medical Journal. There is no work in the English language to be preferred to Dr. Quain's Elements of Anatomy. — London Journal of Medicine. In one volume, octavo, STANLEY (EDWARD). A TREATISE ON DISEASES ( '■■ THE BONES. extra cloth, 2S6 pages. SOLLY (SAMUEL), F. R. S. THE HUMAN BRAIN; its Structure, Physiology, and Diseases. With a Description of the Typical Forms of the I'.iain in the Animal Kingdom. From the Second and much enlarged London edition. In one octavo volume of 500 pages, with 120 wood-cuts. AND SCIENTIFIC PUBLICATIONS. 29 STILLE (ALFRED), M. D. PRINCIPLES OF GENERAL AND SPECIAL THERAPEUTICS. In handsome octavo. (Preparing.) SIMON (JOHN), F. R. S. GENERAL PATHOLOGY, as conducive to the Establishment of Rational Principles for the Prevention and Cure of Disease. A Course of Lectures delivered at St. Thomas's Hospital during the summer Session of 1850. In one neat octavo volume, of 212 pages. SMITH (W. TYLER), M.D., Physician Accoucheur to St. Mary's Hospital, &c. ON PARTURITION, AND THE PRINCIPLES AND PRACTICE OF OBSTETRICS. In one large duodecimo volume, of 400 pages. by the same author. — (Now Ready.) A PRACTICAL TREATISE ON THE PATHOLOGY AND TREATMENT OF LETJCORRHOZA. With numerous illustrations. In one very handsome octavo volume ot about 250 pages. The investigation of the pathology and treatment of leucorrhcen is a task that may well engage the time and energies of the most philosophical and skilled physician ; and there are few men more capa- ble of conducting and deducing important observa- tions from sucli a study than the author of the pre- sent treatise. l;r. Tyler Smith's previous researches, not less than his devotion to physiology and scientific medicine, point him out as one eminently Calculated to throw light on many subjects, which less able men might fail to elucidate. We consequently take his work in hand with high expectations and we have not been in the least disappointed. The fore- going cursory examination of Dr. Tyler Smith's work will be sufficient to prove its value, and we hope more than enough to induce every practitioner to study it for himself. — Tke Lancet. The above list contains simply the general head- ings of the different chapters; to have enumerated all the subjects discussed, or to have made further extracts, would have compelled us much to exceed our limits. This, however, we scarcely regret; because we think a perusal of the extracts given will induce the reader to examine the work for him- self; and we would advise all who are anxious for correct ideas respecting these discharges, and their sources, to possess themselves of it. — Dublin Med. Press. SIBSON (FRANCIS), M.D., Physician to St. Mary's Hospital. MEDICAL ANATOMY. Illustrating the Form, Structure, and Position of the Internal Organs in Health and Disease. In large imperial quarto, with splendid colored plates. To match "Maclise's Surgical Anatomy." Part I. (Nearly Ready.) SCHOEDLER iFRIEDRICH), PH.D., Professor of the Natural Sciences at Worms, &c. THE BOOK OF NATURE; an Elementary Introduction to the Sciences of Physics, Astronomy, Chemistry, Mineralogy, Geology, Botany, Zoology, and Physiology. First American edition, with a Glossary and oilier Additions and Improvements; from the second English edition. Translated from the sixih German edition, by Henry Mkdlock, F. C. S., &c. In one thick volume, small octavo, of about seven hundred pages, with G79 illustrations on wood. Suitable for the higher Schools and private students. (Now Ready.) TOMES (JOHN), F. R. S. A MANUAL OF DENTAL PRACTICE. Illustrated by numerous engravings on wood. In one handsome volume. (Preparing.) . TRANSACTIONS OF THE AMERICAN MEDICAL ASSOCIATION. VOLUME VIII, for 1855, 8vo., extra cloth. (Nearly Ready.) A few complete sets can still be had, in eight volumes, price $38. Applications and remittances to be made to Caspar Wister, M. D., Tivu-urer, Philadelphia. *#* These volumes are published by and sold for account of the Association. TODD (R. B.), M. D., AND BOWMAN (WILLIAM), F. R. S. PHYSIOLOGICAL ANATOMY AND PHYSIOLOGY OF MAN. With numerous handsome wood-cuts. Parts I, IJ, and III, in one octavo volume, 552 pages. Part IV will complete the work. The first portion of Part IV, with numerous original illustrations, was published in the Medical News and Library for 1853, and the completion will be issued immediately on its appearance in London. Those who have subscribed since the appearance of the preceding portion of the work oan have the three parts by mail, on remittance of $2 50 to the publishers. TOYNBEE (JOSEPH), F. R. S., Aural Surgeon to St. Mary's Hospital, &c. A MANUAL OF AURAL SURGE RY; being a complete Treatise on Diseases of the Ear. Illustrated with numerous engravings on wood, from original drawings. In one octavo volume. (Preparing.) 30 BLANCHARD & LEA'S MEDICAL TANNER (T. H.), M. D. Physician to the Hospital for Women, &c. A MANUAL OF CLINICAL MEDICINE AND PHYSICAL DIAGNOSIS. To which is added The Code of Elhics of the American Medical Association. In one neat volume, small 12mo., extra cloth. (Note Ready.) The object of this little work is to furnish the practitioner, in a condensed and convenient com- pass, and at a trifling cost, with a guide for the daily exigencies of his practice. A large portion of the volume is occupied with details of diagnostic symptoms, classified under the different seats of disease. This, in itself, is well worth the price of the book, but in addition, there will be found an immense amount of information, not usually touched upon in the systematic works, or scattered throughout many different volumes — such as general rules for conduct, taking notes, clinical exami- nation of children and of the insane, post-mortem examinations, medico-legal examinations, exami- nations for life insurance, instruments employed in diagnosis, such as the microscope, tests, the spirometer, dynamometer, stethometcr, stethoscope, pleximeter, ophthalmoscope, speculum, uterine *ound, &c. ; directions for the chemical and microscopical examination of the blood, urine, sputa, &c. &c. ; with many other subjects of" equal importance which hitherto the young practitioner has had to learn in a great measure from experience alone. Although necessarily treated in a condensed manner, the topics will be found to embrace the latest and most approved modes of procedure, while the addition of the admirable " Code of Ethics" of the American Medical Association renders it complete as a guide for the student and as a manual of daily reference for the younger practitioner. Those who desire to u