#.* UC-NRLF '.H.S. 1 0*) 3T .%. *r« latitats o y p MJSae HEAtTH LIBRAR THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA PRESENTED BY PROF. CHARLES A. KOFOID AND MRS. PRUDENCE W. KOFOID REMARKS ON THE FREQUENCY AND FATALITY of DIFFERENT DISEASES, &c. REMARKS OX THE FREQUENCY AND FATALITY OF DIFFERENT DISEASES, PARTICULARLY ON THE PROGRESSIVE INCREASE OF CONSUMPTION: WITH OBSERVATIONS ON THE INFLUENCE OF THE SEASONS ON MORTALITY. BY WILLIAM WOOLLCOMBE, M. D. LONDON : PRINTED FOR tOVGMAN, HURST, REES, AND ORME, PATERNOSTER ROW J AND REES AND CURTIS, PLYMOUTH. 1808. Printed by C. S tower, Paternoftc? Row, Londo% >7" PREFACE. IN submitting to the Public the result of his own inquiries concerning some points of Statistical Medicine, the design of the Author will be accomplished, if it shall be found that some useful addition has been made to the stock of authentic materials, some useful suggestions offered, conducive to the more successful investi- gation of subjects, which he deems of importance, of questions in which he thinks the interest of the Public intimately concerned. x IM375I79 11 Of the Tables, which constitute the? essential part of the following pages, the first five ha/e been formed from materials afforded by the register of the medical cases occurring at the Public Dispensary at Plymouth, in a period of seven years from the establishment of the Institution. In framing them the object has been, to exhibit the proportionate prevalence of different diseases, and the absolute and re- lative mortality resulting from them ; as well as to afford grounds for instituting a comparison between the prevalence of diseases in different districts at the same period, and in the same district at different periods. The space of time which they include, may perhaps be deemed too limited, to admit of the deduction of general conclu- sions with much confidence in their vali- dity; yet their coincidence, in many in- Ill stances, with observations derived frona more extended experience, may afford a presumption of their not being altogether unworthy of attention. Many deficiencies in their construction, which cannot be referred to this source of imperfection, will readily be noticed. To account for these in a general way it may be sufficient to observe, that the register of the cases was not made with any reference to the use to which it has been now applied. Its pri- mary object was merely to keep in the view of the Physician the number and character of the cases immediately under his care; and to furnish the means of annually informing the Subscribers to the Institution of the extent to which their charity had been applied, and of the degree of benefit resulting from it. This will account for the deficiency observable at the end of the first Table, where the total number is made up by the addition of a, 11 Of the Tables, which constitute the* essential part of the following pages, the first five ha/e been formed from materials afforded by the register of the medical cases occurring at the Public Dispensary at Plymouth, in a period of seven years from the establishment of the Institution. In framing them the object has been, to exhibit the proportionate prevalence of different diseases, anrl the absolute and re- lative mortality resulting from them ; as well as to afford grounds for instituting a comparison between the prevalence of diseases in different districts at the same period, and in the same district at different periods. The space of time which they include, may perhaps be deemed too limited, to admit of the deduction of general conclu- sions with much confidence in their vali- dity; yet their coincidence, in many in- Ill stances, with observations derived from more extended experience, may afford a presumption of their not being altogether unworthy of attention. Many deficiencies in their construction, which cannot be referred to this source of imperfection, will readily be noticed. To account for these in a general way it may be suificicnt to observe, that the register of the cases was not made with any reference to the use to which it has been now applied. Its pri- mary object was merely to keep in the view of the Physician the number and character of the cases immediately under his care ; and to furnish the means of annually informing the Subscribers to the Institution of the extent to which their charity had been applied, and of the degree of benefit resulting from it. This will account for the deficiency observable at the end of the first Table, where the total number is made up by the addition of ^ IV considerable portion of cases, to which no. distinctive appellations of disease have been assigned. It will not be denied, that the inferences of the relation of diseases to each other, and the proportion of any one distemper to the whole number, must be affected by this omission ; yet the conclusions relating to the diseases of most importance, either as to their prevalence or their consequences, are comparatively little influenced by it ; since the omission of assigning names must generally have occurred in slight and unimportant disorders, with the exception of a few cases, where it may purposely have arisen from the obscurity in which the nature of the distemper was involved. Many of the cases unnamed may, with certainty, be referred to the class of erup- tive diseases, and are so marked in the register; the omission, in this instance, y arising from the uncertainty prevailing at the moment, as to the proper head to which they should be referred, according to the arrangement of Dr. Willan, whose nomenclature has been otherwise ad- hered to. A strict adherence to nosological accu- racy has not been aimed at. In general the names of diseases adopted are those assigned by Dr. Cullen ; in some instances they correspond with those employed by Sauvages. Where any term is used in a different or unusual sense, it is signified in a note subjoined. The inattention and irregularity in attendance of patients at Dispensaries, render precision in ascertain- ing their complaints often impracticable. The valuable work of Dr. Heberden, on the increase and decrease of diseases, having in great measure suggested the formation of these Tables, a comparison of the inferences deducible from them with his observations, naturally became a primary object. And if the following pages be found to contain any confirma- tion of the conclusions of that Author, they may derive from this circumstance a collateral claim to that attention, of which independently they might not be deemed deserving. Several facts, and many grounds of comparison, have also been derived from Dr. Willan's Reports on the Diseases in London ; a work abounding in useful and accurate information, and enriched with the practical observations of a discrimi- nating and enlightened mind. On two subjects the inquiry has been carried far beyond the limits of mere com^ parison. The desire of ascertaining with Vll more precision', than seems hitherto to have been attained, the extent of the prevalence of consumption, occasioned in the investigation of that point a minute- ness, which will be excused by those who are impressed with the importance of the question. The inquiry into the influence of the seasons on disease and mortality, was also deemed sufficiently interesting to justify a more detailed examination of the evidence on which it rests. If the popular opinion on this point be erroneous, the error is not merely speculative, but of practical influence on the inhabitants of this country, Every attempt therefore to correct it may expect a favourable recep- tion, and an attentive consideration. TABLE I. OF THS CASES OF PATIENTS ADMITTED AT THE PLYMOUTH PUBLIC DISPENSARY, FROM NOVEMBER IS, 1798, TO AUGUST 31, 1805. £ in OS s O o ■J3. «> +J a CO o d >> t/3 s to Ph a U < .13 u h ** -9 o 2 1 of each the ality. »o & 80 ■-H l-t « CO o> o t- . •n — o I-* j* pH 00 r— < -i f-i co <© t^ **H —H tn W <*> ■< • • • • en rt IO SB u A en ,c tn en O It u «? rt S s- o h rt a o O ■£3 P S 3 S c .s s < < < «* < < r-* m 00 -* ■ >n — * rt . . B u rt en o Id u o » _ t~ < • • -o • • • • • p • id ^ as zr. tu BO P a? o ri rt o rt o o ^ CO '~ ri ^ ~ ■5 Bti C "E- °u GB 5 £ c* o c 'ti t_ o w; — < ■* < < < -< < ^ < C3 t> CO o o - 1 JJI * -* uo - „_, ^ . t^ CM «N CM o »■> «0 O »H ' o O o o -t-> -»■» ■*< -«J ,H -s *■* t-* o _, « cc TT -<* cj s c c c "** •■* r 1 *~ r-l »— 1 >-i " i— 1 CO cm ec rt C* o es P-* C e^ ^ ©*> •v* «v "* •«? "** "«? i— i m C< c* CM «a CM - BQ ~ -V , o go O J>- cs CO ** ~ OS § oc Vj ~ J> «5 CM e* - CM CM T* «3 tn X - - ^ f) Ch W cc CM _ n rH 1—1 »o ~ CM i> Q i— i •a "* - •o cc - c» t>. -« cm Of - • '• • • O • • • • • • U5 "en W ..« • — = ^ i> 'X: O ^ tw o 8) J; c in « "5 . . o o o o -£ ig rt rt a % c fcr bC O s H ,2$ — ^ > c: ir; a cz _^ P, o o ^ — ~ ~ B ps rt o »*-> U O U o o j^ iO CT> 6 _^ cm V} „. o O t^. -.j »— i w-i — C» on c< r>,- CN CM c* ♦- c * s- * * * 2 — as a & a --3 a c-3 5 - _ c - t^ ©1 <0 o CN Or- >o o r-l •—I *H •H rH rH •* CO CO ■"J" CN -~ tt o eg i^ f— f C-J w — ^ CO co tT so — i c~ O SO rH Of n V-H CO CO ■>»j< — c* •"" 1 CN o i— » rH rH rH c> GO CO CO o» cv — _l o -H rH *h X ©< CO 1^ rH CO ■'J' S< r> — -* o ~J o 'O 00 co CO «r> i-H OB go CO t^ CI co CO •H M Q CO CO CO GO CO 51 CO ~ 51 © -t-> _C o O i— 1 rH l-< 1-1 00 ~ 51 t>. 51 i—i c d 5 d d • -* •"* "T UH -* »-^ ""' " H I— 1 n ■^ -« " ■^ W 1— 1 •& £>. i-< _, U5i to _ b. Oi iH ^ T? a CI r-H «* i— 1 c* CI - 1— 1 - "«* c-* V WJ - rj« e< -« d o 1>- CI n - ~ O ^ M ci O * - Oi - c» - 1 5^> o p— i SI " CO GO o ^ 1-1 CI J> - ei Ot - r^ CN »o ■ rt rt jet "C 3 OS £ -- — •J} *E "d 95 s 3 S 5 C to ci "Si >-> — i .a V c e u bC 3 o s 98 J3 t- O e o « a W a a w w w '— CJ w Ci o ©» so T* »c CO O o 01 ■"tf <* ^3- ■<# T* ■* * "3" * * 9 III! S g " s 9 Si a v O <0 o c* t^ uri «o !-•■«*-» bi Q 1804 - "* - l-H o O lO o oo o> CO ~ * r-t o o 00 ~ rl <0 eo C* r-t c* c< Is rt c< >c '" , r-t «o to CI _ »o Tf - I-* - - «o c* CN *■» >, >s >-. t», c u ■^ *7* _J -M * ~~ •"" ' 1-^ — ■H l-H _, o* CO *a? •o «o t«» CO g, o _ CN SO o s s 13 i-x si OJ so «-« E 2 3-0 ** H* CO ^ in CO T* co CO CO *i> W >/> o» CO H «o 1 O CO TT CN co ** W) C* CO ^H ""* T o c co co i-^ co F-« 30 ■** f* ~- Ul o c< M G< uO —i O 00 i— < — * — * c> «Q ^ ^< . 00 a o „_ ©♦ l> l> t» t> J> t^ K 00 00 co * * , ,. 11 a ^ 'Z c 'O e C3 CT> Tf 3-J <-« CO "- 1 «* CO CO TJF oo CO N> - »M fr- N. CO »o t^» *n CN ee -r IN n - 'O 00 -« «-l1 _ IH c {N ' H t^ -, -O o ?» *• (Si CO eo eo vo C*s «s o CN ri 1— O > 4) 3 3 tn • a o o c '5 o w 3 o 3 3 C o r • s "trt va ■1 u £1 o u 3 a a a 5h s fc> s J2 a. E o "S u o «5" "p c "3 k >n 'O »^ cc o o _ ©3 eo <* eo CO 00 CO cc * CO o o> o» 12 t ~ - z. e* C*i CO O b- O «i 13 o 'O n IN o *tf eo s & CO .2 a h n m « - 1 ci ■ TJ< 00 00 i-l t-i CO rH CO CO CO ^ CO »» l-» C* CM CO J> e) e-> oo rH o "5* ,-< c< oo 5 ~ ca rC O) ™ Oh H o — i -i — 14 <~"5 s !»> Os-- Oi l^ g g « 2 o o 3 *+ «o c> CO 00 ° co cc ■>£> CN _ CM »-o i> ?> Oi s* 00 eo O 00 „ t*. „< oa ^ BQ to ,~ O 00 *-» co oo c-. ,_: o JO 00 CO _ OS Ob — < CO CN fS £> -1» •^ « • SB ^■e >, , o « Z? e es L . — -* 1* « * .'« . "3 "0 .'£ ~?s i~ P i> > > O H — 3 1 1 * "t3 P -J w i* a ; N 00 Oi O — -* cn c^ H - ■ ' 1 j* NOTES ON TABLE I 9. Apoplexla Hydroeephalica. — By the adop- tion of this appellation for the hydrocephalus acutus, vel internus, of the earlier authors, it is not intended to subscribe to the propriety of its application. For this species of inflamma- tion of the brain, peculiarised by its termina- tion in effusion, some distinctive name seems wanting. Is hydrocephalus admissible ? 13. Asthenia. — Sauvages Nos. Meth.'cl. 6. gen. 21. Seeal so observations refcrrible to this title in Willan's Reports on the Diseases in London, p. 52. 17, 18. Ca/igo comece, Caligo lent is. — The first species includes those cases of obscuration of the transparent cornea, which are the fre- 16 quent consequences of ophthalmia, and are dis- tinguished by the terms macula, leucoma, &c. The second comprehends cataract. 19. Cancer scroti.— Tt\k case occurred in a chimney-sweeper of advanced age ; the ul- cerated part was of small extent, and was re- moved by excision. 21. Catarrhus epidemicus. — Influenza. 24. Chorea. — This has been said to be a fre- quent disease in England. In Scotland it is of rare occurrence. The number of cases in the present instance has a tendency to confirm the former observation. In one of these instances the disease had its origin distinctly in terror, in a boy of eleven years of age, in whom it first occurred during Lord Duncan's action with the Dutch fleet. In some of these cases evi- dent benefit appeared to be derived from the continued use of nitrat of silver, which has almost invariably disappointed my hopes in epilepsy. This might reasonably be expected from a due consideration of the nature of the two diseases, and of the probable mode of operation of the medicine. 39. Dysuria — To account for the fatal cases? in this instance it may be mentioned, that 17 under this title are included diseases of the bladder, arising from different causes. See Cullen Nos. Meth. gen. 124, sp. 5 & 6. 47. Febris. — Under no title in the list is the arrangement so liable to exception as in this, to which so considerable a number of cases has been referred ; and in the contemplation of it was made the previous remark, that nosological accuracy had not been aimed at. A large proportion of these cases consists of such, as by reporters are frequently styled "acute dis- eases of children;" a vague and unsatisfactory title, but possibly warranted by the imperfect st^ %t i of our knowledge of their complaints. To these must be added the slighter febrile affections of adults, arising from cold, or other causes ; and those cases, in which the symp- toms of fever, being the chief object of prac- tice, were principally regarded, the primary disease being at the time of admission doubtful or obscure. 48. Gangmna. — Mortification of the toes and feet. Pott's Works, &c. 49. Gastrodynia. — Perhaps these cases should in strictness have been referred to dyspepsia ; but the symptom by which they are here charac- D 18 terized is often so predominant/ as to entitle them to a distinctive appellation. In many instances of this most pertinacious complaint, which occurs almost exclusively in females, the pain of the stomach has entirely arisen from an inordinate use of tea, and has ceased on dis- continuing this beverage. 60. Hydarthrus. — Diseaseof the knee-joint- white swelling. 62. Ilydromeira. — Sauvages. Gen. 289, sp. 2. Ilvdrometra gravidarum. 65. Hysteralgia. — Sauvages. Gen. 209, sp. 6. '5. Mclama. — Of the four cases here set down, two are not strictly referrible to the genus melsena, the characteristic haemorrhage not having in those cases occurred. They are so associated, in defect of a more appropriate situation, because the disease in those instances was deemed to consist in that condition of the vessels of the system of the vena portarum, Vfhich precedes the haemorrhage in melasna, They were the cases also which terminated fatally. SO. Oedema pucrperale. — White — Try e — Wil- lan, 321 — Hull on Phlegmatia dolens. 2 19- S8. Pkurodyne. — The reference of so many cases to this title of Sauvages, which Cullen has not thought entitled to a generic distinction, is another instance of no very strict attention to nosological precision. It is designed in this place to include some cases, which ought per- haps to have been referred to rheumatism, to which Cullen assigns all the species of Sau- vages; some, which were sequels of pneumonic inflammation ; and others, in which neither the precise seat, nor nature of the complaint, was easily to be ascertained. 91. Pompholyx.- — In a recent case of this kind, which has subsisted many months, the vesications have occupied in succession almost every part of the surface ; chiefly the breasts at first ; latterly the belly, thighs, and feet. That the stomach, uterus, ovaria, and urinary bladder, have also participated in the disease, has been rendered highly probable by the oc- currence of disordered function of those 'or- gans. The disease supervened a sudden sup- pression of the menstrual discharge, which has not been restored. Sometimes blood, some- times a watery fluid, is thrown up from the stomach. A considerable and painful tumour has taken place in the left hypogastrium ; and no urine has been discharged during seveia! 29 weeks without the aid of the catheter. In some few instances of this disease, described under the name of chronic pemphigus, there has been suspected to subsist a connexion with disorder of the uterine functions, in the oppo- site conditions of menorrhagia and amenorrhea. 98. Purpura. — Phaenigmus petechialis, Sauv. 308 — Haemorrhsea, Adair Dissert. Inaug. d« Hasmorrhgea petechial^ Edin. 1789 — Petechias sine febre — Purpura, Willan's Reports, p. 90. 105. Scarlatina. — The identity of scarlatina anginosa and cynanche maligna, being ad- mitted, there can be little hesitation in classing the disease with the exanthemata, rather than with the phlegmasia? ; and consequently of em- ploying scarlatina, rather than cynanche, as the generic term. 108. Stomacace. — Sauvages. Gen. 241, sp. 1. 1J3. Tetanus. — In a recent case of this dis- ease, the event was favourable. In the history of it the following circumstances seemed worthy of attention. The disease arose from severe contusion pf the fore-finger, commenc- ing about four weeks after the infliction of the injury. At tjie expiration of another week, 21 when assistance was first applied for, there was no external wound, but the last joint was con- siderably enlarged. From the amputation of the finger some degree of alleviation of the symptoms was the immediate consequence. From the combined and continued use of wine, bark, and affusion of cold water, decided benefit was judged to be derived. From the application of tincture of tobacco to the ex- ternal fauces, the rigidity of the muscles was for a time evidently diminished, and pain mi- tigated. From opium, in doses from one to three hundred drops, and to the extent of two ounces and a half of the tincture, in seventy- two hours, no benefit was apparently derived ; and its effect in producing distressing dysuria could not be doubted. From the use of di- gitalis, by which the frequency of the pulse was reduced, some advantage seemed to be gained. The active treatment of the com- plaint occupied three weeks : the recovery was complete. The patient was a strong man, about twenty-five years of age. In the con- duct of the case the narrator was assisted by the judicious advice of his friend and colleague, Dr. Remmett, Physician Extraordinary to the Institution in which it occurred. 114. Trichiasis. — "Estdirectiociliorum versus oculi bulbum." Plenck. de Morbis Oculorum. TABLE II. OF THS DISEASES CONTAINED IN TABLE I. ARRANGED IN THE ORDER OF THEIR FREQUENCY OF OCCURRENCE. 25 OC W oo ^" <* •Q to Oi to « oo OJ ec 'O »o O* c5 e* — 1 00 O I— 1 "* CO -, ri 91 9 c 3 a B 93 3 5 - — s a L -Z a — B •j) 3 9 CO C H >> CJ — -a >^ >-, £t| 5 Q © ~ — — - £ W M T}« tf» w ts 00 26 *^ t> o Tji T* M eN PS eo CO c* CO c* CN o* e» e>» 0* OS CO *S J3 >-l • SO "31 en * CO P O . • * CO a "3 CO ej u CO d .2 "3 2 <1> c o 8 a> rt a xij CO (* 8 ft CJ 3 en as E o OS B o — a 24 o — it 1— 1 1— ( Q o - 'O ^ CO o> O ©» -V ■<* ^ •^f ** ■j ■<# "5" ^ O *5 >o • ea o igi o -H a eo O »o I-* ^■1 o a. ^ o -, rt d "3 i o R CO i c _d d CO CO CO a 8P u © .2 c > e .3 — 1* c CO p 1 o rt U >> o a 5 d IT. u a. 9 >-* t>- C/9 ■> - « "5 o Q fa D o fa P eo •<* «o >o iO »o »o te> «5 o <© JN oc O-, o c< so co CO so CO CO CO CO M co •"^ 28 •■3 -J3 O- O, -3 I— ( I— I W ■3 'S C O ■a O 1-3 -J-p £ s Oh J- w a Ok s o u c o s c o — 0> o> to a. Is Is is is Is Is is to to to to to- o 43 - o c S s o TO a £5 ^3 e Ol, u B S 03 pC o c C >-> C o m t 43 -S o O. I* o "Si O a. u o o « .2 ri "EL. P^ o <*> pa •a S t> l^ is Is IS t^ 20 8* ■« ■a hi © o «S d 'Sd ft eS "o CO IB © o ft "5b .2 o ft o Si O en b V o 9 C a C S 9 *-> es a a a- S >> Q •4-1 CO c < ft < < s — CN « «* o 'O N. oo &> O rt 0* o O O o o O o o o XL = c o — 'u « c a oi «< on v) +3 A a ft 0} CU 4> •J3 ■-" « 30 wm- - - - o ft o * • • " - 71 o H or. a t. rt S o .= -C « u o f- 8 i- rt H H H > co a o »— t i— i ©* c* <-S i-« i-» i-t . . , ^ m m 2 • • • • -' d C b> eS « a 'a '-3 £ o C o J3 13 m o rt >» >-» ^ A s — - » CO « »ft TABLE III. Of THE DISEASES CONTAINED IN TABLE I. IN WHICH FATAL EVENTS OCCURRED, ARRANGED IK THE ORDER OF THEIR FATALITY RELATIVELY TO EACH OTHER* 33 O Ci nf d o 2 o ■ • ' " c d a >-> u o J- 3 n d "to to 3 en ^3 d .5 d d 1 'E. d — o Cm < 'to 3 -4 J- d s u O - ,0 d ,0 d en o — c o O o 3 Oh d £ fe c T3 s d ft - ft 9 34 M tS o .5 S 3b -5 SB t« u 13 a c hi o a a, "a. bfi C "cu *5 1> V O W W w o HH CU PS H o — < a 'to ft S CL. o a 1/3 s fi £ CO =3 J2 o Oi o TABLE IV. OF THE SAME DISEASES AS IN TABLE III. ARRANGED IN THE ORDER OF THEIR FATALITY, RELATIVELY TO THE NUMBER OF CASES Or E.'.CII DIS- EASE, AS STATED IN THE LAST COLUMN OF TABLE I. 37 M TT in 1—1 o p^ T)" Tf 1 Tf 1Q a d e s d '13 !> o in t^ ee rt s -c -C > d ja -a 3. ^3 o «j rt Ph U H -> H d S >i O rt G* QO 38 ""* CO CO o» CO Tf< 00 OS CO eo m O H CM ■"* 1-1 1-1 '"* e>i CO eo >* «* ^J" a a a • a a a a a n 3 CJ> a a " * • .5 "5c . o . . *"~» rt eg rt eg a Oh M U, 8 ,C eg « O s o ferH ■2 43 oj O. u £ «3 S J3 u ed CD ea U Q . "a. an O o» ffO -* »o CO )^ 00 OS CO CO CO CO GO eo CO eo so CO co IfJ CO CO eo co CO T*

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U i_ - £ '- rt rt rt « rt rt rt y y y y y ■ i. n >s ^ ►% J*> >s ;>-> >» N'QS'OOifl'O M *• ** W ~^ O* « u * ■a = = c J >> CS td % = O S • >s = •Si o.3 5 s S Q U « a be a ^ - -5 -fi -a ? o 2 E « i £ s •a -5.2 c £ .3 ■ ^S 'g o^ >■» _i, ;»*— ^ « s " -3 C vi c« ■ B *• U «J j~ c e &:« 51 si E to ** co o o q (X e» oo cm o CO 90 1-H !-• • t* 90 00 o I-H C< CO 6? eo n b. CC 00 t> CO <0 CO C7> cr> ri o o c< CO •> *-• z> 'O «o >o O, C5 O t«» t> GO O O o> t"» G> O 0> "I 1 t> l> l> *» CO so co t> 1>- «> o -2 £ © © o © -*-> -w ^ «■ ■? T* £ O i * C£ cs ^ 5 **! o 52 E § o -5 o M £ M ° "U «S •- "i 5 M B E "B ° '5 8 s iJ u c< ,5 .s S" si « O — b ■s ft. bo C K a > Js ~ - 3 O f :a fe ■" c „ .fa -o g ui * -g tf 3 £ S fc «? a t* .s s° S P* s * j- F. «* H.-S a- .5 ■g bft.B '< B -5 g a s "s o. a g B -5 *3 *» *-* o -3 5 e.e £ 3 a v a *J . ^ u bo _e ° OT I s - "5 'bo a "O !? ?r 3 u « — » O O « *3 *j -5 2 .S e **■ a* .£ Bj 8 ■a s u 13 3 U "5 i -c * B j * * ■r «»j " > J Q . n J & .2 ■"" a. o S § | E 1 3 JF X £ - g -° t= p« £ ^ H S * f a * y I JH O ft. o u x )X. ^ .a >; tl bo r 5 . X U V .' »D ^D TJ 3 2 "« p^ £ *" vC « u u 3 ft< u u > > 3 B oa 1 CO »^- 2 Gti a! c EQ "3 3 o c c h u u 2 bo o Ed u u H ^3 w i si r 4 £ IS £ B * •" to r~ * o> 1) S3 ' From the first part of the preceding table it appears, that the absolute and re- lative mortality from consumption has been regularly increasing during the last cen- tury ; though it seems to have been con- siderably less in its relative proportion at the commencement of this period, than it had been fifty years before. Dr. Heberden has stated this augmentation, in a gross way, by the following figures, the total mortalitv in each instance being 21,000, Deaths from Consumption. At the beginning of the 18th century, 3000 —■ 1 to 7. At the middle of the 18th century, . 4000 = 1 to 5. 25* At the end of the 18th century, , 5000 = 1 to 4. 2> If he is correct in his statement of the proportion in the first period, there must have been a great decrease in deaths from consumption in the first years of the cen- tury, since the relation in the last five years of the preceding century is, as stated in the table, l to 5. 8. On the contrary, in stating the proportion in the third pe- riod as 1 to 4. 2, he is not supported by the average of the last ten years of the 34 century, which makes it as i to 3. S. As there is much reason to believe that the general mortality has for some time been on the decrease, relatively to the increas- ing population of the country, it admits of a question, whether the number of deaths from consumption, which, relatively to the deaths from all other causes, is with- out doubt very considerably augmented, is in reality increased, relatively to the population of the country. In other words, dees a larger proportion of the in- habitants of this island fall a victim to this disease at present, than did at the close of the seventeenth century*? * Many arguments might be mentioned, which would a priori have rendered probable the extension of this dis- rate. Of this fort is the argument drawn from hereditary disposition, which, if admitted, must be allowed to have considerable influence. In an opulent and flourishing country, where population is on the increase, many weakly children will be reared, who, in a less improved state of society, must have perished in early infancy ; and consequently there will be a larger proportion of adults obnoxious to a disease of this description. In such a country a much larger proportion of the people will be occupied in sedentary employments, in manufactories sub- servient to the arts of luxury and refinement- The altera- 55 That consumption has for some time been, and still is, an increasing disease in this island, is presumed from the increased relation of deaths from this disease to the whole mortality at the present period, contrasted with the relation it bore at dif- ferent periods in the last century and half, as exhibited in the bills of mortality. As- suming the variation in this relation to be a just measure of the absolute increase and decrease of the disease, it will appear from an inspection of the first part of the sixth table, that at the close of the seventeenth century the consumptive mortality was less than it had been in the middle of that century, by nearly one- sixth part ; that in the middle of the eighteenth century it had somewhat increased, but was still considerably less than it had been an hun- dred years before ; but that at the close of this century its increase had been so great, as not only to equal the mortality in the tion in diet and clothing affords arguments of an equivocal nature. How long this may be the case in the latter instance is perhaps not doubtful. The female costume of Greece is indeed elegant, but our climate is not- Attican, 56 first period, but to exceed it by nearly one- fifth. The relations of the mortality at these four periods, or half centuries, in the succession above stated, correspond to the following numbers, 48, 58, 54, 38. To the assumption of this increase of the relative mortality, as a measure of the real increase of consumptive mortality, two objections occur. First, it may be said, that the increase of consumption within the bills of mortality is no proof of its general increase in the kingdom at large, since this may be attributed to the operation of local causes ; and, secondly, it may be stated, that an increase in the proportion of mortality from one disease to the whole mortality, is no proof of its absolute increase ; since the apparent aug- mentation in the former mav have arisen from a real reduction of the latter. Each of these objections is entitled to attention. To the first it maj be. replied, that al- 57 though the ratios of consumptive morta- lity in a crowded metropolis may not at any period be a measure of relation justly applicable to the kingdom at large, yet that those ratios may justly be compared with each other at different periods ; and, that from the comparison may be formed a scale of variation, which may be justly applied as a measure of increase and de- crease to the w T hole kingdom, unless any material change can be supposed to have taken place in the local circumstances of the metropolis within the period. It is not, however, obvious that any such change has taken place in regard to London. The Improvement of the city, after the great fire in J 060, certainly tended greatly to the increase of its salubrity, and might, perhaps, contribute to the relative decrease of consumptive mortality which is ob- served after that period, although its known influence in putting a stop to the preva- lence of plague, and in mitigating the ravages of other contagious distempers, by which the sum of the general mortality must have been diminished, would rather 58 lead to a different conclusion. But what local change of circumstances has occurred in London in the la^t thirty years, to which, with any plausibility, can be attributed the great increase of consumptive mortality within that period? Great as the addi- tion to its population has been, equally great has been the extension of its build- ings ; and there is little reason to believe that the inhabitants are now more crowded than they were formerly. On the con- trary, the local improvement of the me- tropolis is believed, by the most compe- tent judges, to have contributed largely to its general salubrity ; and it seems highly improbable that to the same local circum- stances should be owing an increase of mortality from one disease, and a diminu- tion from all others. Such a consequence might indeed seem to be involved in the rapid increase of the population of the metropolis, because the emigration from the country, by which this increase is made, takes place chiefly at that period of life, which is deemed most liable to the invasion of phthisical disease. This cir- 59 cumstance may perhaps account for the greater proportion of phthisical mortality in London, compared with the countrv, and otiier towns of less magnitude ; but cannot be allowed to have any influence on the relations subsisting in London at different periods, because the metropolis must at all times have drawn its recruits from the country under similar circum- stances, But the relative increase of consump- tive mortality of late years rests not on the sole evidence of the London bills of mor- tality. It is confirmed by two instances in the second part of the sixth table, the cases of Holvcross and Ackworth. In the instance of tlolycross the increase is so great and so rapid, that it is difficult to believe that some mistake has not been committed in the numbers, although the unusual accuracy with which the record of that parish was kept by Mr. Gorsuch during thirty years, is adverse to such a supposition. If it be correct, it proves Co that the mortality from consumption was nearly doubled in the space Of ten years in a small parish, in which, during that period, very little variation occurred, either in the population, or in the general mor- tality. In the other instance of Ack- worth, the increase, in the space of ten years, amounted to one-eighth; an in- crease of a very serious nature, if the short space of time included in the observation, be considered, as well as the period itself, which was from l£5; to 1767, at which time no great increase had begun to take place in London. The period of vast in- crease at Holyeross was from 1 7G0 to 1770, from which latter year maybe dated the augmentation in the London bills. The second objection which, it was observed might be stated against the pre- sumption of absolute increase of consump- tive mortality from its relative increase at different periods, is grounded on the dif- ficulty of ascertaining whether this in- crease may net be apparent only, and 61 arising from a decrease in the general mortality. If, for example, the inhabitants of this country "had, in the year 1700, been six: millions, the proportion of mortality one ,in forty, and the proportion of consump- tive mortality one to six, the total deaths would have been 150, 000, and those from the disease under consideration 25,000, If in the year 1800 the inhabitants had been the same in number, and the deaths from consumption had been known to have increased relatively one-third, or to be in the ratio of one to four, stiil might there have been no increase in the absolute fatality of consumption ; but a reduction of the general mortality might have taken place in the same proportion, so as to have become as one to sixty ; in which case the total mortality would be 100,000, and the consumptive mortality still 25,000*. This * These, and subsequent statements of a similar nature, may be more readily comprehended by referring to the following calculations, founded on the assumed relations pf mortality : — 62 objection is therefore not without weight, and shews that, in order to establish a relative increase of mortality from any efts- ease to be a just measure of its absolute augmentation, we must ascertain the pro- portion of deaths to the inhabitants of the country at the particular periods be- tween which a comparison is instituted. As this proportion is not, and cannot be ascertained with precision, we must be satisfied with such an approximation to the truth as can be derived from the im- perfect evidence found in those authors, who have treated of that branch of poli- Population. Proportion of _. . ,. Tr »«*«= fcpuUtioa. Mortality to „55?, t:.e <_ r.=urr. ; r.. e ft* Pr.m.lariV.n. Morta.. ;. to the total C Mortality. tton. — 6 = 31.250 -4- 4 = 46,875 «£. 6 = C7.777 — 4 = 41.66G — 6 = 25.000 '•4- 4 *= 37,500 — 6 = 18,518 — 4 = 27,777 -f- C = 16,666 -4-4 =^25. U ,000,000 ~ 40 = 275 3 000 . . -^- S = 55,6CQ 60 = 100,000 63 tical economy, with which this question ii connected *. * Writers on political economy have in rain endea- voured to ascertain with precision the relations of mor- tality to population in the same country at different pe« ri>>ds. The collected information on this subject, recently obtained bv the returns to Parliament in answer to the question- proposed in the Population Act, has also proved insufficient to establish with any degree of accuracy the subsisting mortality in this kingdom at the present period; much ie-o to contrast it with the relations which have pre- vailed at antecedent periods. If the actual return of burials from the abstract of the parochial registers were complete, the annual average of deaths during the last six years of the past century would be found to be, to the population of the kingdom, as one to forty-seven. But these returns are confessedly incomplete from various causes, among which may be mentioned, a total absence of returns from some parishes ; known, and reasonably pre- sumed, omissions in those registers from which returns have been made ; and a deficiency of any return of burials occurring in places of interment, belonging to different societies of dissenters from the established church. Of the additions, which ought to be made to the sum of re- corded burials on account of these deficiencies, there are no data on which a correct estimate can be founded. This difficulty subsisting in the ascertainment of the absolute number of deaths, Mr. Malthus has presumed that the proportion of mortality to the population in this island, at the present time, may be stated as one to forty: the lowest proportion of deaths, he observes, that can well 64 Presuming, for the present, that in the year 1700 the mortality in England, in be supposed in the circumstances of the country,' and, if true, indicating an astonishing superiority in healthiness over the generality of other states. In adopting the ratio thus assumed by Mr. Malthus upon grounds con- fessedly imperfect, less scruple may be entertained from the probability that, if it be erroneous, it deviates from the (ruth by supposing the proportion of deaths to be less than it really is ; and consequently, by employing it as a measure of comparison, there is no danger of drawing ex- aggerated inferences in relation to the absolute mortality arising from particular diseases. If, however, the assump- tion be just, it confirms the persuasion, prevailing among medical inquirers, of a progressive decrease of the fata- lity of disease in general ; a decrease, which may be at- tributed in great measure to improved habits of the people in respect to cleanliness, to the adoption of measures during some years past to prevent the diffusion of con- tagious febrile diseases, and in some small degree, it may be hoped, to the gradual improvement of the healing art. The influence Avhich preventive medicine may have on the population of a country, is at present strongly illus- trated by the effects of the introduction of vaccine inocu- lation. It cannot be doubled that this practice has/ since its introduction, considerably diminished the annual mortality. It must not however be supposed that this diminution is in the same ratio with the decrease of deatiis from small pox, since that were to presume that the vac- cinated children were exempted from death by the agency of any other disease. Mr. Malthus has stated his belief, 65 proportion to its inhabitants, was one to thirty-six; and that the relative increase that, if the introduction of the cow-pock should effect the extirpation of the small-pox, a perceptible difference will be found in the increase of mortality from some other diseases, supposing the proportion of marriages to remain undiminished. The statement of this belief, which is un- avoidable, seems to have been strangely misconstrued into an objection to the practice of vaccination. The principles of that author, and the reasonings founded upon them, for- bid such an inference, even if it stood not in contradiction to the direct avowal of his inclination to believe, u that the gradual light which may be expected on the interesting topic of human inquiry in which he has engaged, will teach us to derive from the extinction of a mortal disorder a real blessing, a real improvement in the health and hap- piness of mankind." The political economist, who adopts the principles of Mr. Mai thus, could he direct at will the population of his country, would adjust the balance between the supply of inhabitauts and the means of subsistence, by the opera- tion of the preventive rather than the positive checks to superabundant population. It would consequently be his aim to prevent premature mortality, and his endeavour to preserve, by every means, the lives of those in existence, whether as already contributing by their exertions to the common support, or as advancing to the period when they would become qualified to sustain their share of active employment. He would estimate the death of every indi- vidual prematurely cut off, as a loss to the state, in the K 66 of consumptive mortality has, in the course of the century, amounted to one- proportion in which, according to his age, the expense of his maintenance had already exceeded the amount of his productive labour. Such an economist would be a most strenuous advocate for the application and extension of preventive medicine. He would deprive small-pox of its victims by encouraging vaccination : he would oppose the ravages of con'agious fevers, by instituting houses of reception : and he would check the influence of disease ia general by promoting habits of cleanliness and sobriety. If , by this preservation of life, his population increased beyond his means of subsistence, he would employ his preventive check to obviate a redundance, and by di- minishing the number of marriages, he would adjust the supply of births to the real wants of his society. That by so doing he would greatly increase the productive labour, and augment the power of his people, in proportion to their numbers, will not be denied ; but that he would increase the sum of happiness in his community mav, per- haps, be doubted. Would he not necessarily condemn a large proportion of his people to celibacy, and upon the remainder accumulate the difficulties, the cares, and the anxieties, inevitably attendant on the support and educa- tion of numerous families ? The effects which have now been hypothetical]}- attri- buted to the interference of the politician, will, in the present state of things, be produced by the operation of natural causes. A general decrease of deaths, whether it be effected by entirely closing one of the great sluices, or 67 third, or is become as four to six, it fol- lows that there must have been an absolute by narrowing all the channel?, of mortality;, must be pro- ductive of a reduction in the number of marriages, and, consequently, of births. Whether such consequences would be in themselves salutary, or conducive to the augmentation of the sum of human happiness, is an inquiry beset with too many difficulties, and involving foo many abstruse considerations, to be entered upon here. This, at least, we can perceive, that the provision for the multiplication of life prevails over the provision for its preservation ; and hence we may safely conclude, that the ultimate ten- dency of this is beneficial. It is sufficient for us to know, that the preservation of life is a duty incumbent on man ; that the means of effecting it, to a certain extent, are placed within his reach ; and that experience has shewn that those means have not been ineffectually employed. The decrease of mortality, which has been presumed, and partly proved, to have taken place of late years in this kingdom, is probably owing, in great measure, to the preservation of infant life, which the introduction of vaccination has a tendency to augment in a much greater ratio, than any of the various causes, by the combination of which it has hitherto been effected. But the diminu- tion of mortality in general, and of early mortali*) in particular, inevitably tends to increase celibacy. Aug- menting the probability of a larye family, giv.s force to the influence of the preventive check to marriage. This probability has been increased in the higher and Middle ranks of life since the introduction of variolous inocu>a- 68 increase to a certain extent, unless in the same period the proportion of mortality to population has become as 1 to 54. But this supposition is too extravagant to require refutation. It is sufficient to observe, that an uncommon degree of healthiness is attributed to this island, when it is admitted, that the mortality at present may perhaps amount only to 1 in 40. Admitting, however, with a late author, that the last-mentioned proportion is just, let us inquire what the proportion must have been in the year 1/00, to ac- count for the difference of the relative mortality of consumption, upon the sup- position of there being no absolute in- tion, and of various improvements in the treatment of children in early infancy. On these classes of society it may be presumed to have exerted its influence insensibly, in conjunction with other and more powerful causes. If the fatality of small- pox should be annihilated by the uni. Tersality of vaccination, the probability of more numerous families will extend also to the lower orders ; and on them it must be expected to have a similar effect. But its influ- ence here will be counteracted by the happy want of fore- sight in some, and, in others, by the consideration of the encouragtments to marriage, which it is the tendency of almost all our charitable institutions to propose. 4 6Q crease. In that ease we shall be con- strained to state the general mortality in 1700 to have been l in 27 nearly, which implies a degree of imhealthiness incon- sistent with the known condition of the country at that period. It is obvious, that no such proportion of deaths, as has been stated in these two instances, could have happened without such a corres- ponding augmentation in the population of the country, as is known not to have- occurred, and is altogether extravagant to suppose. From the foregoing considerations it seems to be clearly established, that the apprehension of the increase of consump- tion is not vain and imfoun d The degree of that increase will probably be estimated differently bv different calcula- tors; but will not, by any mode of cal- culation, be shown to be meorisiderable. Without pretending to otfer the following comparative statements as conclusive, I venture to propose them as probable ap- proximations to the truth. 70 Suppose the inhabitants of England to have been, at the commencement of the seventeenth century, six millions, the annual mortality one in thirty-six, .and the consumptive to the general mortality one to six. In this case, the total num- ber of deaths from consumption must have been 27,777. Suppose at the close of the century the inhabitants to be the same in number, the consumptive mor- tality to have increased to the proportion of one to four, and the annual mortalitv to have sunk to one in forty. In this case it is evident, that the absolute in- crease of deaths from consumption will be less than its apparent relative increase of one third, in the same proportion as the total mortality has decreased, which is by one ninth ; in other words, the absolute number of deaths from consumption in this case will be 37,500, instead of 41,666, the number to which thev would have amounted if the proportion of general mortality had remained unchanged ; and the absolute increase will be equal only to somewhat more than one-fourth. n If it should be thought that sufficient difference has not been allowed for the increased healthiness of the kingdom at the end of the century, under the known circumstances of its increased population, let us suppose, that in the year l,"oo the annual mortality was so great as one in thirty-two, in \v T hich case the consump- tive mortality would have been equal to 31,250; and consequently the increase in the century would have amounted only to the dirference between that number and 37,500, that is to 6250 ; and the absolute increase, instead of being one-third, would have been one-sixth. Yet if this should be deemed a juster measure of increase for the whole century than the preceding, still it cannot be considered as a just measure of the increase for the last thirty years; during which period, whe- ther we refer to London, or to the coun- try, we find reason to believe, that the consumptive mortality has increased in a much more rapid ratio than it had in the preceding part of the century. 72 In these hypothetical statements the population has been supposed to be sta- tionary, because no alteration in it does in any manner affect the argument ; but when the increase of consumptive mor- tality is admitted, the augmentation of the population can no longer be disre- garded in estimating the magnitude of the evil. From an examination of the two parts of the sixth table it appears, that during the last half century the proportion of consumptive to general mortality has been as l to 4.2. But as the consump- tive mortality may be comparatively less in the country than in towns, from which the grounds of the calculation have been chiefly derived, to avoid exaggera- tion, let the proportion for the kingdom at lame be stated to be as l to 5. If this be admitted as just, and if it be granted that the annual mortality is to the population as \ to 40, while it is ascertained that the inhabitants of Great Britain amount to eleven millions, it will be found that the 73 ANNUAL VICTIMS TO CONSUMPTION IN this island are not less than fifty- five THOUSAND PERSONS. If the period of life, at which these victims perish, be considered, the loss in a political point of view will assume addi- tional importance. The popular notion of consumption, as one of the ministers of fate, is chiefly drawn from its effects in the superior - and conspicuous ranks ol society, where it more frequently com- mences its attack at an early and interest- ing period of life. From the numerous instances of this kind, which real life daily presents to our view, and fiction continually employs to heighten the scenes of imaginary distress, we are led to confine in idea the influence of this dis- ease to an earlier and shorter period of life, than that to which it is in reality extended; and consequently to consider it as peculiarly destructive to those beings, by whom the relations have not yet been formed, which, connecting the indivi- dual with the community, combine in L 74 their dissolution the public with the pri- vate loss. But if from these scenes of conspicuous woe, we turn to the humble walks of private affliction, in the lower and laborious classes of society, in the great mass and strength of the people, we shall find it prevailing at a more advanced age, at a period at which the preservation of existence, politically considered, is an object of peculiar value. It assails the labourer and the mechanic in the prime of life ; not an insulated, unconnected, in- dividual, but the father of a family, which he leaves helpless and indigent, a burden on the public to maintain. Nor is this protracted influence less extended to the females in the same rank of life. The sufferings they frequently sustain in be- coming the mothers of a numerous off- spring, too frequently call into action the latent seeds of the disease ; and from the circumstance which renders the continu- ance of their life of increased importance, is traced the source of their untimely death* 75 From statements of Dr. Haygarth and Dr. Aikin it appears, that one half of those who died of consumption in two years at Chester, had passed their thirtieth year ; and at Warrington, three eighths had passed their forty-fifth year. At our dispensary, the number of those who have died beyond thirty exceeds the number of those who died before the attainment of that age, in the proportion of two to one*. The period between thirty and forty seems to be most fatal, the deaths within * Deaths from Consumption, Under 5 years of age Between 5 years and 10 10 15 « 20 30 , 40 Above 60 - Under 14 Between 14 Abuve 45 Total 135 45 Plymouth. 3> O i 5^ >26 e( 10> 26- -26 13" •23 75 76 that term being equal to all those occur- . ring before thirty, and rather greater than those happening after forty. The importance of determining the interesting question, whether consump- tion be an increasing disease, may justify the length to which the pursuit of the inquiry has been extended. If the increase of consumptive complaints be established as an incontrovertible fact, if this increase has already proceeded to the extent which has been rendered probable, and is still advancing with accelerating rapidity, the promulgation of it must surely add energy to the warning voice, which has loudly demanded, without having sufficiently awakened, the attention of the guardians of the rising generation to the danger which threatens it. If it be established as a fact, let us not vainly hope to find an antidote to its ravages in the hidden stores of nature ; but let us rather strenuously seek to ascertain the causes of its extended influence; and endeavour, by all the arts of prevention, to obviate the attack of a foe, which prudence may assist us to avert, but no prowess will enable us to overcome*. * It is no part of the design of this tract to enter into the investigation of the causes here alluded to. Its aim is simply to excite such an inquiry by others, possessing a wider field of observation, and to be a preliminary step towards it. The inquiry, indeed, will be unnecessary, if the preliminary fact be not established ; and, if it be not, it must be owing either to a fallacy in the sources whence the premises are drawn, to errors in conducting the calcu- lations, or to inconclusive reasonings from them. But if from the above statements, as they now are, or as they may hereafter stand corrected by just criticism, the conclusion be verified, the future inquirer will at least not be stopped in limine, as the author of a late inquiry into the changes in the climate of Great Britain, by a denial that any change had occurred. In speaking of the chance of curing consumption, it is far from my intention to depreciate the merits, or abate the zeal of those, by whom new methods of trial are re- commended ; but only to state the smallness of the chance, for the purpose of .quickeuing attention to the necessity of early recourse to prevention. In attempts to cure the disease, when formed, we generally have the earnestly concurrent assistance of the patient and his friends. In applying the means of prevention, have we not, too often, the concurrent counteragency of both these parties ? The alliance, which at first might have been decisive, is with- held ; until it is at best fruitless and unavailing. ;a Having thus deduced from the evidence contained in the sixth table, the extension of phthisical disease in general, our atten- tion is recalled to the more immediate object of inquiry ; its relative influence in this place, compared with other places mentioned in the table, especially those in the second part. If the average of consumptive mor- tality at Plymouth be compared with the general average deduced from the same source in all the places cited in the second part of the table, collectively taken, it will be found to differ only in the small proportion of one seven- teenth, the relation of the former to the latter being as 4.28 to 4. If London and Bristol be excluded, it will somewhat exceed the average of the remaining places, the relation in that case being as 4.28 to 4.3 G.- But that the difference in the latter instance would have been reversed, and in the former considerably augmented, if the comparisons had been instituted from data derived from identical periods, is a conclusion warranted by the preceding remarks in proof of the pro- gressive increase of the malady under consideration. For it cannot have escaped observation, that, while the average of mor- tality from the other places is drawn from documents which do not extend beyond the year 1773, and are included within that and the year 1747, the average of Plymouth is derived from a period so much more recent, that the far greater part of it extends into the present century. But if the average of Plymouth be con- trasted with those averages, which are deduced from periods nearly correspon- dent in time, of which we have instances only in Bristol and London, it will be found that the phthisical mortality at Plymouth has of late years been nearly one fourth less than in London*, and less by nearly one half than in Bristol*. In the unsettled state in which Europe has for some time been, and in which she * Tab. VI. P. II. 80 is probably destined long to continue; while in some countries the genial influ- ence of climate is denied by open hostility, and in others neutrality is no longer per- mitted to afford a sanctuary even to the votaries of health ; it has become an object of increased importance to determine, what places in our own island are best adapted to the residence of those, who are assailed by the " giant malady of the country" The mildness of the winter season in the south-west of England has of late vears induced consumptive invalids to seek refuge in Devon and Cornwall* It would certainly be an object of curiosity and of utility to ascertain the frequency and mortality of indigenous consumption in these counties, relatively to other dis- tricts in the eastern, northern, and mid- land parts of the island. Unfortunately for this inquiry, most of the calculations we possess, are derived from registers kept in large towns, and consequently liable to be influenced by various local Si causes. On account of this influence it has been suggested, that the number of Bo * cases of consumption occurring at Ply- mouth may not afford a just criterion for estimating the relative frequency of the disease in the western part of the island ; because the occupations and habits of many of the inhabitants of this town are conceived to be peculiarly favourable to the production of the disorder*. Various employments in a sea-port necessarily ex- pose a large proportion of the labouring class to the severities and vicissitudes of weather; and under such circumstances the inducement to a more free use of spi- rituous liquors, will be aided by a greater facility of obtaining them. Of this argu- ment it may be deemed no trifling con- firmation, that the proportion of males to females, whose deaths from consumption * This objection was suggested by a physician of this place, who, in the course of his extensive practice, has had frequent opportunities of observing the greater preva- lence of consumptive complaints in the little towns and Tillages on the seaside near Plymouth, than in the country at large. This he ascribes lo the combined operation of the causes assigned. M -. 82 are recorded in the first table, exceeds three to two ; a proportion the reverse of that which might have been expected, if the greater exposure of men in sea-faring oc- cupations had not been adverted to*. It may also be objected to the applic- ation of a proportion derived from the phthisical mortality of a Dispensary only, to the district containing that institution ; that consumption may be presumed to be more prevalent among that class which applies to such charities for relief, than among the middle and higher ranks ; and consequently, that the relative mortality will be greater in that portion, than in the aggregate of the inhabitants of the district. Consonantly to this supposition * This presumption of the greater liability of\the female sex in general is not, it must be confessed, warranted by the only other instance in point, which has occurred to me. In this the proportioa of males exceeds that of fe- males, although in a far less degree than in the instance above-mentioned. At Ackworth, in Yorkshire, there died of consumption, from 1747 to 1767, thirty-three males and twenty-eight females, which is in the proportion of 8.25 to 7, S3 it will be observed in the sixth table* that the proportionate mortality, stated from Dr. "Willan's general practice, ex- ceeds that deduced from the bills of mor- tality ; which could not have happened, if Dr. Willan's statement had not been materially influenced by the description of his patients, a large proportion of whom, notwithstanding the known extent of his private practice, must have been derived from the Carey-street Dispensary. In considering the effect of these objec- tions in the instances cited in the table, we shall find, that the latter alone, and that partially, applies to Dr. Willan's statement ; and that the former is applic- able to Bristol and London, f where the combined operation of exposure and in- temperance must assuredly be experienced in full as great a degree as at Plymouth) and not to Shrewsbury and Chester. If therefore, the mortality at Plymouth be contrasted with that at Chester or Shrews- bury, an allowance must be made for the local reasons assigned in each of the objec- 84 tions ; but if the comparison be made With Bristol or London, such a correction only is necessary as may be warranted by the second objection. Upon the whole it appears not improbable, that more accu- rate and comprehensive statements might confirm the opinion entertained of the comparatively favourable influence of the climate of the west of England on con- sumptive complaints. One observation more respecting this disease shall suffice. In the first table, the whole number of cases of phthisis is stated to be ]g8, and of deaths 75; and accordingly in the fourth table, the pro- portion of mortality is said to be as l in 2. 6l. But from this statement it must not be inferred, that the recoveries have been in this proportion. The practice at our institution lays not a claim to such suc- cess. This disagreement will be ex- plained by recollecting, that in the course of seven years the same persons may have been admitted at different times, labour- ing under the same disease, and at each 85 time of admission may have been consi- dered as distinct persons. Some also having been relieved, and discharged for the purpose of going into the country for change of air, may have there died unre- corded. Others, wearied with a long attendance, desire to be discharged, and resigning themselves to their fate, sink at' last unnoticed into the grave. What allowances are to be made on these ac- counts cannot be easily estimated. In early stages of the complaint some bene- fit is doubtless derived from preventive medicine, in removing the disease, or in deferring the period of its fatal attack ; and certainly some rare instances do, from time to time, occur of recoveries under circumstances apparently most unpromis- ing. By the recollection of these our hopes are animated, and our feelings reconciled to the task of attending the victims of this disease, the most painful office of a painful profession. The disease, which from its importance claims the next attention, is fever, the so prevalence of which in this town is, as has been already hinted, less extensive than might have been expected from the consideration of its populousness, its liability during war to an excessive in- crease of its inhabitants, and to its expo- sure to contagion from its intercourse with fleets and armies. The proportion of typhus to other dis- eases at our Dispensary, on an average of jj seven years, is as l to 20.2. At the ¥ Dispensary in Liverpool, we find from \ the tables given by Dr. Currie*, that the : proportion of typhus to other diseases was, on an average of seventeen years, as 3 to 4.5 nearly. In that period the num- ? her of general cases admitted at the Dis- * ^ pensary amounted to 213,305, of which 48,367 were cases of typhus. In the 4 space of seven years the number of gene- ral cases admitted at our Dispensary has been 44og, of which 218 have been cases of typhus. * Currie's Medical Reports, &c. 550, ?d. edit. &7 But before a comparison can be insti- tuted on these data, some circumstances must be taken into consideration, which may materially influence the result. In the first place, the disproportion will be made much more considerable by deduct- ing from the general cases, admitted at Liverpool, one sixth part*, as the proba- ble proportion of surgical cases, which '■ are not admitted in these tables. But, on • the other hand, it is probable, that this . difference would be counteracted bv the * j addition of all the medical cases admitted ;-* in the same period into the infirmary at Liverpool. And as cases of fever are not , admitted into this infirmary, and as Ply- mouth has no such institution, it is obvi- . ous that this addition must be made, be- - fore we can institute a fair comparison between the proportions of fever to other diseases, to which the same class of peo- ple in the respective towns is liable ; the * In assuming the surgical cases to be one sixth of the whole, the proportion is adopted, -which actually subsists in a return for September, l790 r stated in page 225 of the work abore cited, as care of the general diseases being in the one instance divided between two estab- lishments, and the care of the particular disease being restricted to one of them, while in the other instance, one establish- ment includes the admission of the parti- cular as well as the general diseases. This necessary correction cannot be made, owing to the number of admissions into the Liverpool Infirmary being unknown. A correction is also required, on the other hand, in the Plymouth statement, since the proportion ought to be increased by deducting from the general cases all those . which have occurred in persons not residing within the town ; as it is obvious from the nature of the Institution, that no cases of fever occurring in persons of this description can have been admitted* Still, however, after making these con- trary allowances, there will probably be no great error in presuming the prevalence of fever to be more extensive among the lower class of inhabitants of Liverpool, than it is among those of the same de- 89 Scription in Plymouth, in the proportion of four to one. This amazing difference must, however, Without hesitation, be ascribed in a much greater degree, to causes rendering Liver- pool peculiarly obnoxious to the influence of fever, than to causes operating to ren- der Plymouth peculiarly unobnoxious to similar influence. Of this, little doubt can be entertained, when it is known, that of the inhabitants of Liverpool "seven thou- sand live in cellars under ground, and nearly nine thousand in back houses, which in general have an imperfect ventilation, especially in the new streets on the south side of the town, where a pernicious practice has been lately introduced of building houses to be let to labourers, in small confined courts, which have a communication with the street by a narrow aperture, but no passage for the air through them. Among the inhabitants of these cellars ff 90 and back houses typhus is constantly present*." The proportion of fever cases at Ply- mouth approaches nearer to that which appears to obtain in London. From an average of Dr. Willan's practice, during four years, it appears that the cases of fever were to the general cases as 1 to 10, the total number of the former being 11,484, of the latter 73 if. Here, how- ever, it must be observed, that Dr. Wil- lan's cases included not only those admit- ted at the Carey-street Dispensary, but also those occurring in his own very ex- tensive private practice among the middle and higher classes of society ; and as the * (Turrit's Reports. Sec. 2<22, Cd. edit. ^ See Reports on the Diseases in London. — It is here necessary to observe, that, in estimating the number of fever case*, in Dr. Willan's Monthly Reports, I include not only what he styles contagious fever, but his synochus and slow fever, because I apprehend the term typhus, ia the other instances, to have been employed in the extensive sense in which it was applied by Cullen, and, conse- quently, to ha^e embraced all those cases. 01 prevalence of fever in those classes is comparatively very inconsiderable, we are probably entitled to deduct such a number from the general cases, as will render the proportion of fever to the re- mainder as l to 13, or even 12. It must, at the same time, be remembered, that a contrary correction must be made, as in the case of Liverpool, on account of the London hospitals, from which fever is also excluded. In Dr. Clarke's relation of the recent proceedings at Newcastle, for the estab- lishment of a house of recovery*, there are many facts relative to the prevalence of fever, in that and some other towns ; but there are not sufficient data for instituting a comparison, even on the grounds assumed in the preceding in- stances. In one placef , he speaks of the • Collection of Papers intended to promote an Insti- tution for the Cure and Prevention of infectious Fevers in Newcastle, kc. By John Clarke, M. D. t Part I. p. 19, note. 02 number of cases of fever in one year hav- ing amounted to 425 ; in another*, he gives the number of cases admitted at the dispensary in four successive years, the average of which is 15(5. But as he does not state the total number of cases ad- mitted in the same period, the relation of one to the other cannot be obtained. We may, however, arrive at a conclusion by another process, namely, by finding the proportion of fever cases to the number of inhabitants. The number of fever cases admitted at the Newcastle Dispensary, assuming 150 as the average, is to the population of that town, estimated at 30,000, as 1 to 231. And if the number of general cases admitted at the Newcastle Dispensary be to the inhabitants at large in the same relation as the corresponding number is at Plymouth, namely, as l to 24, then it will follow, that the propor- tion of cases of fever, at the former place, is as 1 to 10. Part I. p. 56. 03 Upon the whole, from these premises', which must be allowed to be but imper- fect, we, shall perhaps approximate the truth in supposing the relative occurrence of fever to other disorders, among the lower class of inhabitants, to be in Liver- pool as 1 to 5 ; in Newcastle, as 1 to 10 ; in London, as 1 to 13 ; and in Plymouth, as 1 to 18. This calculation will appear less objectionable, when it is recollected, ihat the best evidence in its support sub- sists in the two instances, which form the extremes. Few remarks remain to be made on the other diseases included in the first table. The decrease of intermittent fever in this district is sufficiently obvious, by contrasting its rare appearance at present with the frequent mention of it in the writings of Dr. Huxham. Yet, from an observation of that author*, connected * Ex quo sane tam udas habuimus tempestates, febres intermittentcs omnigenae per has regioncs grassata; sunt 94 with subsequent experience, it should seem that the prevalence of intermittents in this place, at the period when he wrote, was owing to accidental circumstances ; and that the present, as well as previous, exemption from this disorder is to be ascribed to local and original causes, and not to the operation of those general causes, connected with the agricultural improvement of the country, by which its influence in this island has been confined to very narrow limits. Dr. Heberden remarks that there is scarcely any fact to be collected from the bills of mortality more worthy of atten- tion than the gradual decline of dysen- tery. In the seventeenth century, the number of deaths under this head appears maxiiiie, etiam in hoc oppido et per viciniam ; cum tamen annis abhinc viginti veras intermittentes rarissime viderim. Imo bene memini milites plurimos, emeritos, ad arcera nostram olim transvectos ab oris Icenis et Portu magno» pertinaci admodum quartana tantum non confectos penitus, qui tamen hie, a sola benignitate cceli, convaluere protinus, -r-Huxham de Aerc, An. 1735, p. llf. 95 to have been never less than one thousand, and sometimes to have exceeded four thousand. In the eighteenth century, the decline was constant, regular, and rapid ; the average number of cases, in the first ten years, amounting to one thousand and seventy, and in the last ten years only to twenty. Yet, from the year 1733, colic has been included under the same head with dysentery. Our tables confirm the infrequency of these diseases. Dysentery is almost unknown ; and the decrease ot colic in this town, during the last thirty or forty years, has been, I have reason to think, very remarkable. Its relative oc- currence is as l to 133, and its propor- tional mortality as l to 321. Of dysen- tery no fatal case has occurred. The increase of apoplexy and palsy, Dr. Heberden observes, has been gradual and constant. The proportional mor- tality from these diseases is now more than double what it was a hundred years ago. On the average of the last five years of the last century it appears, from the 06 bills, lo have been as l to 50. Our table confirms the observation, as far as relates to the present times, by giving the relative mortality as l to 32. Dropsy is one of the diseases, which appears to be rather on the decline in the southern part of the island. This seems to have been in great measure effected by the operation of the duties imposed on dis- tilled spirits. The proportional mortality from this disease, as deduced from an average of the last three years of the eighteenth century, in the bills, corre- sponds, very nearly, with that afforded by our table, being in the one instance as 1 to 20.8, in the other, as 1 to 19. The proportion of cases of dropsy to the gene- ral cases is as 1 to 36. I am inclined to believe this proportion much less than obtains in the northern part of the island, where the use of whiskey seems still to retain a predominating influence on dis- ease. Has this species of distilled spirits a peculiarly destructive influence ? In certain districts of a neighbouring county, 5 97 where brandy is supposed to have been drunk with a liberality proportionate to the facility with which it was once ob- tained, I have been assured by a gentle- man of accurate observation, whose op- portunity of forming an opinion had been long and extensive, that dropsy did not particularly prevail. Yet the free use of spirituous liquors, as a frequent cause of dropsy, rests on evidence too strong to be questioned, Diabetes, I am led to believe from my inquiries, has been in this neighbour- hood a disease of rare occurrence. Our table gives only two instances ; and nei- ther of these furnished a well-marked case of the disease. It has been supposed to be more frequent in Scotland than in England ; yet in a place where diseases of curiosity are sought after with avidity, and where in diseases little understood relief would be sought from distant parts, twenty cases only occurred to Dr. Cullen, in his long practice. And in the same situation thirteen years afforded only o 98 twelve instances to Dr. Gregory, and twenty years the same number to Dr. Duncan. At the conclusion of the first table is stated the total number of cases treated at the Dispensary in the first seven years of its existence, together with the total NUMBER OF FATAL EVENTS arising OUt of those cases in the same period. If a comparison of these numbers had afforded any presumption of more than usual suc- cess, I should silently have participated in the gratification resulting from the reflection, that the liberality of the pub- lic had produced a more than wanted share of benefit to the objects of its com- passion. But feelings of a different ten- dency cannot influence me to forbear contrasting the real mortality, as it fairly and simply stands,* in our Institution, with that which obtains in other establish- ments of a corresponding, or nearly simi- lar nature. From the great difference in the proportional mortality at different institutions, as stated in the subjoined 99 table, it will probably be inferred, that no great confidence can be placed in any comparisons on this head, unless the nature and mode of conducting the res- pective establishments were better known. A source of material difference arises from the admission, or exclusion of sur- gical cases, the proportion of deaths from the latter being always much smaller than from the former. The mortality also, on several accounts, may be presumed to be greater at dispensaries than in hospitals. In the former, diseases of all descriptions, and at all periods, are admitted ; while from the latter, contagious distempers, as fever and small pox, in most instances, and consumption in many, are excluded : and how large the proportion of fatality from these sources is, needs not to be recapitulated. How inferior the chance of success in dispensary to that in hospital practice is, will be obvious to him who reflects on the situation of the diseased poor man in his miserable habitation, often without 100 necessaries and without attendance, or with these, when supplied, most inju- diciously employed, and contrasts it with the condition of the same person trans- ferred to a ward of a British hospital. It may perhaps be said, that a large portion of cases admitted at a dispensary are of a slighter nature, and such as would not be sent to an hospital ; and therefore, that the mortality should be proportionably less. This observation is certainly just, but it is applicable only to those hospitals where out-patients are not received. But it will not escape remark, that in the following table the greatest differences subsist in the reports from dispensaries; and this difference appears to be totally irreconcilable in the first two instances, where a more than common correspondence might have been presumed to obtain. It is equally impossible to reconcile the report of the Carey-street Dispensary, under Dr. Wii- lan's direction, with the result of that 101 physician's general practice, as well pub- lic as private. That the total proportion of deaths in our dispensary is large, I am still inclined to believe from perceiving the proportion to be unexpectedly large in two or three prevailing disorders. In typhus the loss has been one in six ; whereas in the Newcastle Dispensary, and in the Edin- burgh Infirmary, the loss is one in fifteen, and in the Whitehaven Dispensary one in twenty. In pneumonia the proportion of deaths with us is also one. in six. In the first instance, the difference may partly arise from a diversity in the appli- cation of the term typhus. Perhaps many of the cases included in our table under the title febris might have been classed as slighter cases of typhus ; and had this been done, the apparent mortality would have been much less. An observation, common to fever and pneumonia, but more decidedly applicable to the latter, is, that admission is too generally deferred to a very late period of the disease. Of 5 102 the hundred and thirty eight cases of pneumonia, I suspect there was no op- portunity of employing the lancet in a fifth part. The list of deaths is swelled also by the fatal effects of small pox, of the cases of which one half has proved mortal. If delay in applying for assist- ance be observable in the two last-men- tioned diseases, it is still more remarkable in this ; but I am far from thinking that a difference in the event would so cer- tainly follow a contrary practice in the latter instance as in the former. But whatever the influence of this cause may be, it is difficult to conceive its operation confined to our institution, unless indeed the novelty of the establishment may be supposed to involve such a consequence. TABLE VII. AVERAGE OF DEATHS AT SEVERAL INSTITUTIONS. 105 l« 'nS t>- « tf) N O 3 :: « 5) - o B3 — d SB r g o Ct-i >— < -1 ■ a PS s ~ —* O a o cS X "i •- - -— ri O — < u ■x. \^.<*J Chi C- £ < o V. ^i - u »; ■3 5 c > -— - = >> ~ I-*" £ B ft u PS ,= :3 s ~ S- " a o En r >-> J -g" s ' 2* 1 fs Dfl > 5 S c o 7. 2 Q X >-,- o - " " • ° = lo(5 - ' i£5 10 »Q o d o > >s >, *-> >■. >» -a o " oc CO «H l-H r-i e<5 (2 • /»^> -^ i~, >"~» t_ S- « . . ^ . . 3 S en t . c o o PS — CO <— i O 1 & CO as og s • • co • • • * • ♦ *b U (3 r-«. bB C c e U . 2 3 . -5 CO • CO Q a -_ 3 "S. i a jo 2« «- o | o c _% o ' g § s j= T3 w P3 O W H O .2 -£ g .2 S o ^ u -d u g *S '^ *' ^ S * j= U4 « - o ■5 s S* -5 ^ c b 3 5 ^ a t: > J= o .S .t: as «■• O 2 « pu E . °* 2 0> 4* .a < £ &• PART II. TABLES ILLUSTRATIVE OF THE INFLUENCE OF THE SEASONS ox MORTALITY, WITH OBSERVATIONS. In the following tables, the number affixed to each month is the aggre- gate amount of the deaths in that month of all the years of the stated period. In the second division of each table the succession of the months is arranged in relation to the increase of deaths in each of them. The second number affixed to February denotes the amount of the deaths, upon the supposition of the assignment of thirty-one days to that month. Ill TABLE VIII. *BLANDFORD. 40 Years— 1733 to 1772. fJune I 190 1 Summer (.February j 218 ) 511 606 991 3 >2231 J f March Spring ^ April J> 193 J- 634 (.May } 223 } 3 213 ) 1240 August 144 July 145 / September 1(55 December 168 October 172 November 174 June 190 April 193 May 218 February 218 — 235 January 220 March 223 • Phil. Trans. The deaths from small-pox, of which a separate account is given, arc not included in this table. / 112 TABLE IX. * CHESTER. 2 Years— 1772, 1773. Summer 38 > 138 f June 1 61 1 ler 1 .luly V 38 > (August ) 39 ) ( September ") 37 } «J October V 56 > (_ November J 73 J C December ') 82 Winter -^ January > 69 (February ) 81 Autumn^ October > 56 > 166 ( November C December 232 ry 3 81 i March Spring J April , 105 May 111 September 37 July 3S August 39 October 50 June Gl May 63 March 65 April 67 January 6*9 November 73 February 81 — S" December 82 * Phi!. Trans., vol.64, Gj 1 1*4 TABLE X. •WARRINGTON. 1 Year. C June 1 22 Summer < July f l6 ^ 54 £ August f September Autumn ■< October > 1 1 > 30 (_ November 84 f December Winter < January J> 35 ^-94 £ February (March 1 35 ) Spring 1 April > 29 > 84 (.May ) 20 ) 262 } 178 November 6 October 1 1 September 13 July 16 August 16 May 20 June 22 April 29 December 29 February 30 — 33 January 35 March 35 • Phil. Trans, vol.64. Q 114 TABLE XL PLYMPTON - MAURICE, PLYMPTON SAINT MARY, PLYMSTOCK, adjoining Country Parishes iu the County of DEVOX. 6 Years— 1779— -1S04-. f June 1 36 1 Summer { July > 23 V 91 (.August ) 32 ) (September ] 40 ] Autumn «> October > 43 > 120 I November ) 37 ) f December ^ 39 1 Winter ^ January > 48 > 139 £ February ) 52 J (March 1 35 1 Spring < April \ 64 > 156 (May J 57 ) 211' 506 1 295. July 23 August 32 March 35 June 36 November 37 December 39 September 40 October 43 January 48 February 52 — 5& May 57 April 64 115 TABLE XII. ST. ANDREW, CHARLES ; STOKE DAMARELL; EAST STONEHOUSE ; comprising the towns of PLYMOUTH, PLYMOUTH-DOCK, and STONE- HOUSE. 6 Years— 1799— 1804. f June Summer 1 July )> 638 J>2059 I August i -h , - >42(j5 f September 1 725 Autumn 1 October V 751 S-2206 (November J 730 ) f December 1 820 1 Winter ^January > 860 >2485 (February J 8 °5 J f March Spring V April ^ 856 } < 25S6. (May \ 7l6 } V 638 >2( J 705 ) V 751 V22( J 730 ) I 8 ' ) 81 7 899 1 }■ 856 y ) 831 ) 2 >9336 1 5071 July 638 August' 705 June 7l6 September 725 November 730 October 751 February ; 805 — 870 December 820 May 831 April 856 January 860 March 999 116 TABLE XIII. •LONDON. 15 Years— 1728, 1743. r June Summer < July V AU2I August -) 30197-) £28210 \ 89235S 3 30829 > f V 191382 r September -^ 33375 -\ I Autumn < October J 34590 S 102146 J t November J 34181 3 r December ■) 35952 -\ Winter 2 January S 37682 S 10979J (■February 3 36157 > Spring J April (•March -) 37126} ) April > 34242 > (.May 3 33410 3 104778 ! 4 214569/ >40595l' July 28210 June 30197 August 30829 September 33375 May 33410 November 34181 April 34242 October 34590 December 35952 February 36157 — March 37126 January 37682 — 39002 * Short's Observations, &c. — Heberden, p. 47, U7 TABLE XIV. ♦YORK. 7 Years, /•June -> 274 -j Summer l July > 220 S731 - i August -> 237 ■> f U23 . /-September -) 225 -\ \ Autumn J October [ 237 J 692 ) ^ I November > 230 > & I * c December -) 292 -\ ^ / 3 Winter 3 January > 320 J894 C February -> 282 -> , March -) 316 ■) Spring ? April \ 277 Ss5S I May ? 263 -> July 220 September 225 November 230 August 237 October 237 May 265 Jane 274 April 277 February 282 — 306 December 292 March 3] 6 January 320 • Heberdcn, p. 49» U8 TABLE XV. COUNTRY-TOWNS IN ENGLAND. I\Ian.y years. s June Somifler < July <• August ' 13034- > 30509' 136SO 3 12795 5 12999 r September 1 < October } 13629 J 40702 Winter Spring . 13629 I t November 3 14074 3 'S0211 December •? January •j 15658 -^ M6932 J4S716. February 3 161 26 3 > 17641 -j > 17670 J 5 1929 3 1661s 3 180856 J March 1 lay c Man >Apri (.May 100645. August 12795 September 12999 July 13034 October 13629 June 13680 November 14074 December I0608 February 16126 —17422 May 1661S January 16932 March 17641 April >176?0 * Short's Observations, &c— Heberden, p. 4?. I1Q TABLE XVI. Comprising the aggregate numbers of the eight preceding Tables. June -^45176 r j une i Summer 1 July [42325 £ 132293 t August ) 44797 2 s September -\ 4757.0 Autumn •? October Winter Spring I November J 49505 • ; 7 >494S5) > 146573 J 40 505 J r Jjecemuer -\ i>d040 -\ < January > 56166 > v. February J 5 375 1 * i March -^ 56340 ^ April (-May -\ 56340 -\ S533G8 >161220 3 51482* 275871' 324177 >6Q304S July 42325 August 44707 June 45176 September 47570 October 49480 November 405O5 May 51482 December 53040 April 5339S February 53751 January 56166* March 56340 * July 42325 August 44797 June 46682 September 49165 October 4 94 SO November 51153 May 51482 December 53040 Ap'ril 55177 January 56 166 March 56340 February 58069 * In this column the months are supposed to contain an equal num- ber of days, viz. 31. The calculation has been made by adding to each of the months which consist of 30 days, i-ioth of its number, and by adding to February 3-28ths of its number, after deducting i-- r- 1 p* o Q O o H Ci O - o P< * 9 C S H H * £ JS ^ to pq ~ 3 1 b- 1 J o 1 CO CO 1 o b. " 'tojg g »■« *■* oo e» eo r? to o> ■<* ■*? «o K OS o> o — 'N.Cir}«0. tf50>0>couo'0 eo 1 CO o c rr otioio^ooie»-«« iO -HrfO(N^Oi^«M CO 00 iO •o W«iQOKXONOO<0 Tt< pH rt I— < i-H r-i CC (N GO o o O* xt*uo — — t^eo — co^tN •M X X CO cy"?f <0 Tf C, X N'O c t-» i> t> is iO i— r* 00 o> O 00 O o Nk^flKWOMMMO 00 r^ oo ■* ^tseicTOCNK'O'O'O 1> •H PJ< 50 u t* u u £> o >-> • 3 o •- c u 2 6 S bfl Sum Aut Win Spri ' 12^ "S 3 — « -S .2 rt Z 3 Z -5 'I § ■ ► — • o o* c o 3 -9 ■5 tt .5 ■ 53 S S .2 3 -S s c * 122 TABLE XVIII. PROPORTION OF DEATHS IN EACH OF THE MONTHS OF FIVE YEARS, as in the preceding table, the months being arranged in pairs, according to their respective distances from the middle of summer. 964 91 } 3367 1212 V 123 in < fa a fa fa o -"= It- H f= £ ^ X O fa t— t p^i o x ■53 l-M o d <; w w O v-2 00 i— i P3 cn « <1 H CO H -3 fa < Q. fa O en en fc ^ o « >— 1 ,a H a fa O u* fa WJ o s o El, o o X X) CM co c o oc CO o o CO CO OJ O C- 00 — <0 NO M fl -t CiCi>Cl NO CN O* G* C-t CO CO C* O* — • — '-' "- 1 -J<30^O l O'r}<<©C0-«'*00C0 ir > ^-H^(N'o'o«i>o^ i e' t oo) 4 s -2 ~ b 3 — ^ C r ~ — -fl in *S'"8 , gJo§ia5l'3JS»§u ?■« ° « S o- ^kS =; - = > a. -* o !N o* co Co -* ~ r* ^ Tf 95 CO CO CO s. CO ^ "* rt C» »0 t-» SO 'O *fJ *>• 'O CO CI CX CO o f «5 OOOMMO'l'OlSlOStH -^i 124 TABLE XX. PROPORTION OF DEATHS IN EACH OF THE MONTHS OF SIX YEARS, as in the preceding table, the months being arranged in pairs, according to their resp Sye distances from the middie of summer. 67\ 54 \ 285 124/ 125 TABLE XXL NUMBER OF PATIENTS ADMITTED AT THE PLYMOUTH DISPENSARY, in each month of six years, from September, 1799, to August, 1805, the succession of the months being ar- ranged in the order of their abundance in disease*. 1 August . , 298 2 July • 313 3 June * . 316 4 April • . 322 5 October • . 323 6 December • , 323 7 September . . 331 8 November . 331 9 May • , 339 10 February (371) 344 11 January . • . 347 12 March • . 363 3950 * To obviate a possible objection it may be observed, that the faci- lity of admission at this institution is at all times such as to preclude the idea of the admissions being influenced by any other cause than the wants of the applicants. 120 TABLE XXII. NUMBER OF PATII OMITTED AT '■■ PLYMOUTH MSPENSA1 in each month of six yea*, from September, 170Q, to Anau=t. 1805, the months being arranged in their natu- ral succession, and classed in seasons, as in Table XIX> 1999\ ?95G 1951 / 127 The prevailing opinion in this country of the influence of the seasons on disease and mortality is justly observed by Dr. Heberdeii to subsist in opposition to the evidence of the clearest facts. Of these facts some are passing in constant and daily review, while others are derived from less obvious, though more conclu- sive, sources. But the prejudice, which prevails in defiance of the former, re- ceives a very limited correction from the latter; while it acquires continual sup- port by deriving its origin from various sources. The influence of the ever-vary- ing condition of the atmosphere of this island on the animal spirits of its inha t- tants, has been conceived to give a colour to opinion in many instances. That in the present instance it should prove a source of erroneous judgment, is little to be wondered at. Those who, to employ their own metaphorical and delusive ex- pressions, feel their bodies braced, their nerves strung with new vigour, and their spirits elastic, will naturally infer, that the sharp air, the keen frost, the serene 128 sky, to which these effects are ascribed, must be more propitious to health, than the warm, moist, and foggy atmosphere, in which they had previously been op- pressed with languor, and enfeebled by relaxation. Hence is derived the uni- versal interchange of congratulation on the healthfulness of the weather, when to a mild and open November succeeds the keen frost of January or December. At a period, happily remote from our times, when England was subject to the frequent visitation of pestilential disease, the approach of summer was dreaded as the harbinger of the plague ; and winter was hailed as the deliverer from its ra- vages. And in our own times we have had such frequent occasions to lament the wide-wasting ravage of disease in the warm climates of the western world, where British valour sinks into an un- timely and inglorious grave, that analogy, the fruitful parent of fallacious conclu- sions, leads us to associate the ideas of warmth and contagious distempers in our 129 own temperate climate. But the fevers of contagious origin in this island prevail undoubtedly to a greater extent in the winter than in the summer ; and the ex- planation of the fact is found, in part, sufficiently obvious, in the less ventilation of the houses of the poor, in which con- tagion is generated, in winter than in summer. Sparingly provided with the supplies of artificial heat, they sedulously exclude the entrance of external cold ; and preventing as much as is possible the renovation of the air in their rooms, they breathe with little intermission a highly vitiated atmosphere during a considerable length of time. Perhaps in considering the origin of the popular belief, the force of early impres- sions and early associations in those classes of society, on whom, on most occasions, depends the cast of public opinion, may be entitled to some atten- tion. In this, as in many other instances, we trace the influence of classic lore. From the poets of Greece and Rome we s 130 imbibe early notions of the beauties of spring. Their enlivening descriptions, true to the feelings of their authors in the genial climes of Italv and Greece, have, with poetic licence, been transferred to our northern skies ; and the shivering in- habitant of Britain talks of the approach of spring in the language of Arcadia. But it is not to poetic description alone, the influence of which is insensibly so ex- tensive, but to the pages of science also, that this illusion is to be traced. From the dictates of Hippocrates and Celsus originated, we may presume, the creed of the physicians of modern Europe on the salubrity of the seasons. " Saluberrimum ver est ;" (says the elegant physician of Rome) " proxime deinde ab hoc hiems ; periculosior aestas ; autumnus long^ peri- . culosissimus ;" and in the succession of eighteen centuries this observation has not become less applicable to the country in which it was originally made. In modern times the records of Marseilles and Mont- pelier, which may be cited in defect of 151 evidence immediately derived from Italy, correspond very nearly with this descrip- tion of the year. At the latter place, the mortality from June to November exceeds that from December to May nearly in the proportion of four to three. At Mar- seilles, the difference is on the same side, but not in the same degree. The strongly contrasted winters of ] 7Q5 and l/Q'D will, in all probability, be adduced in future, as irrefragably refuting the opinions, which in this island attri- bute unhealthiness to a mild, and healthi- ness to a severe winter. But, although this instance will justly be appealed to, as placing the fact in a striking point of view, yet the admission of the general position cannot reasonably be expected, without the production of evidence in its support on a much more extended scale. Of this nature is the proof adduced by Dr. Heberden from the London bills of mortality, supported by the concurrence of similar conclusions deduced from regis- ters in some other towns in England. 132 The principle also, on which the conclu- sion is founded, receives confirmation from records at Paris and throughout the kingdom of Sweden. In the preceding tables (from VIII. to XXII.) is collected and arranged various evidence on the question, as far as it re- lates to this kingdom, derived from the recorded mortality at different periods and at different places ; and particularly, in conformity with my design of illustrating relative local mortality, in this town and its vicinity. In the division of the year into four seasons, the boundaries have neither been assigned with precision by nature, nor definitely prescribed by custom. In the distribution of the months into the re- spective seasons adopted in these tables, no arrangement more correspondent to nature seemed practicable, while an equal portion of time is to be allotted to each season. The protracted arrival of sum- mer for many years past justifies the as- 133 tmeat of its commencement to the month of June, and the mild, open, and days" of many a November i »cue this calumniated month from being delivered over to the gloomy period of winter. But, however this dis- position may be objected to in the kalen- dar of the naturalist, the medical inquirer will, it is presumed, find in the tables themselves sufficient reasons for its adop- tion. In deducing inferences from the six- teenth table, no risk is incurred of erro- neous conclusions from the operation of partial causes. It includes a mortality to the extent of six hundred thousand per- sons, occurring at various periods in the course of the last seventy years of the last century, in towns and in the country, in places remote from each other, and sub- jected by situation to as great variation of climate as can occur in so limited a space. The counties of York, Middlesex, Lan- caster, and Devon, from their relative position, may be presumed to afford a 134 mean of the variations of the weather, indicated by the barometer^ thermometer, and hygrometer, in the southern division of the island. From this table, thus comprehensively formed, it appears, that the mortality is greatest in winter ; but little less in spring;' considerably diminished in au- tumn ; and in summer much further re- duced. The difference between the mor- tality in summer and winter is nearly as four to five ; and if the summer and au- tumnal period be contrasted with the winter and vernal portion of the year, it will be as six to seven. Retaining this table as a standard of comparison, in ex- amining the other tables, from which it is formed, a generally prevailing corre- spondence will of course be expected. Some variations in degree will, however, be found, and some deviations from the general course. The difference between the winter and summer half-year is less in the London table than in any of the others, and greatest in Warrington, Ches- 135 ter, and the country parishes in Devon- shire. Mav it hence be inferred, that, where the relative general mortality is least, the proportion between the morta- lity in summer and winter will be great- est ? For example, in the district in De- vonshire confined to the three towns, the annual mortality is 1 in 25* ; in the dis- trict comprising three adjacent country parishes, it is l in 45 : in the former, the deaths in the summer half-year are to those in the winter as to 7, in the latter as 5 to 7 . Or, is the difference of pro- portion in London to be ascribed to this circumstance, that the metropolis has less than the usual proportion of persons of advanced age, whose deaths happen most frequently in winter, owing to the retire- ment of many towards the close of life, and the increased proportion of people of * Perhaps tiic annual mortality is in this instance stated too high; the grounds upon which it is so stated, are mentioned in page 151 note. For the purpose, however, for which the statement is here made, it is sufficient that e mortality be admitted to he greater in lar , f .••■> ns than in the country, which Is un ScniabSe. 130 middle age derived from the perpetual recruits, which the population is receiving from persons of that description ? The deviations from the general infer- ences are chiefly to be found in the eleventh table. In the country parishes, from the registers of which it is formed, the mortality is greatest in spring, and is particularly excessive in the months of April and May. As in winter it is com- paratively less, so in autumn it is rather greater. May it from these facts be in- to j duced, that life is more directly subjected to the influence of weather in the country than in towns ; and that the diseases of spring and autumn, particularly of the former, are those to which the inhabitants of the country are most obnoxious ? If the limited extent of the table forbid the confident adoption of these conclusions, to future observations must be left their establishment or refutation. Further exceptions occur in the eighth, twelfth, and fifteenth tables, and also in 137 the tenth. In the three first, spring is found to exceed winter in fatality, and in the last summer yields in healthiness to autumn. If an exception be taken to the ratio of comparatiye mortality deduced from the aggregate table (XVI.) on account of the influence of the London table, which has been shewn to differ materially from the others, the necessary correction will pro- bably be made, and an approximation to a fair general average obtained, by stating the deaths in the winter half to exceed those in the summer half of the year by one fifth of the whole. But if no such exception be taken, the mortality in the different seasons may be apportioned on the following scale, presuming upon the grounds formerly stated, the whole annual mortality of Great Britain to amount to 2/5,000. Mortality in summer 60,400 autumn 66.800 spring 73,650 winter 74,150 T 275,000- 138 To each of the tables is subjoined a succession of the months in the order of their fatality. If, for the purpose of comparison with other months, an equal number of days be assigned to February, this month will be found most abundant in deaths. In one or two instances only it is exceeded by March and April. June, which is classed in the most healthy sea- son, yields, in many instances, in salu- brity, to some of the autumnal, and even winter months. If from the records of death in large districts, in all the various forms in which it assails mankind, our attention is direct- ed to its more confined operation in a small i circle, where it acts through the medium of decided disease, it will appear from the deaths at the Dispensary in six years, that the difference in the influence of the seasons is still more strikingly con- trasted. From the nineteenth table it will be found, that the deaths from De- cember to May inclusive exceed those in the remaining months in the proportion 13Q of three to two ; and that the mortality in the winter is double to that in the summer period. But it may be justly observed, that the scale of mortality in the different months is not a criterion of their respective un- healthiness, if that is to be estimated by the frequency of disease. If in times past, when vaccination had not yet ex- tended its security to millions, influenza had prevailed in the spring, and small- pox had raged in autumn, the former sea- son might doubtless have been deemed the most sickly, although the latter would have been distinguished by a dreadful su- periority in fatality. But exclusively of extraordinary sources of variation, the proportion of death will certainly not be found to correspond with the proportion of disease occurring in the same month ; neither will so marked a difference be ob- served to subsist between the unhealthi- ness of different months, or seasons, by the one criterion, as by the other. At least these conclusions seem to be war- 140 ranted by the monthly returns of admis- sion to the Liverpool Dispensary during seventeen years, and to the Plymouth Dis- pensary during six years. At Liverpool, the succession of the months, in respect to the frequency of disease, is in the following order : March, April, January, October, May, Decem- ber, November, February, June> Septem- ber, July, August. At Plymouth, the succession upon the same principle is March, January, February, May, Novem- ber, September, December, October, April, June, July, August ; and the dif- ference in the two months, which form the extremes, is only as eleven to nine. If the contrast be extended to longer pe- riods of time, the twenty-second table shows, that the proportion of patients admitted at the Dispensary in the summer is to that in the winter as nine to ten, and that the proportion in summer and au- tumn is to that in winter and spring as nineteen to twenty. \ 141 The popular opinion of the extensive prevalence of autumnal diseases is not confirmed by this statement, in which autumn maintains the second place among the seasons in the scale of salubrity. The refutation, however, of this opinion can- not be rested on inferences derived from the limited period of six years, in which the autumnal epidemic cholera has not been of frequent occurrence. These and many other points mav easi- ly be determined, if they shall be deemed worthy of further investigation. Upon the whole, sufficient proof seems to have been adduced, that in this coun- try the warmer months are most favour- able to the health of the inhabitants ; and that disease and death extend their influ- ence with the increase of cold in our ordinary winters. That their influence is prodigiously augmented by any extraor- dinary degree of cold, the winter of 1795 has placed beyond all question. 142 Sufficient proof has also been adduced, that the prevalent diseases of Great Britain are those which are most liable to be in- fluenced bv temperature. Few subjects relating to health are so generally misun- derstood as the effects of temperature, or so completely under the control of popu- lar prejudice. The lives, and what is of infinitely more importance to human hap- piness, the health of numbers will be pre- served, when it shall be better and more generally understood. At present it is peculiarly unfortunate, that the prejudice in favour of cold contributes, in many in- stances, to augment the disposition to disease ; and the prejudice against its em- ployment too often deprives the physician of the most efficacious mode of combating disease in existence. APPENDIX. 145 No. 1. PROPORTION OF MORTALITY TO POPULATION. In the preceding pages, when assuming the annual mortality in Great Britain to be to the population in the proportion of one to forty, the difficulty of ascertaining this relation in general was adverted to. It may not, therefore, be superfluous to subjoin the following observations relat- ing to this subject, from the works of u Dr. Price, together with a table, the ma- terials of which, with some exceptions, have been drawn from the same source. " The ingenious Susmilch, to whose works (says Dr. Price) I owe my observa- tions concerning Berlin, makes the pro- portion of people who die annually in great towns to be from 1 in 28 to 1 in 24 ; in moderate towns, from l in 28 to l in 31 ; and in the country, from 1 in 40 to 1 in 50. The observations and facts, produced in this work, prove, T think, that these proportions may be more truly stated as follows : In great towns, from 1 in lg or 20 to 1 in 23 or 24. In moderate towns, from 1 in 23 to 1 in 28. In the country, from 1 in 35 or 40 to 1 in 50 or 60. " To these proportions exceptions will, however, occur in particular places from local circumstances. " Susmilch supposes the proportion of inhabitants of the country to those of towns to be 3i to 1 . This, I think, he 14; has rendered sufficiently probable in Po- merania, Brandenburgh, and some other countries. In well-peopled countries, the proportion may be just: in Sweden, it is computed that the inhabitants of the town are to those of the country only as 1 to 13." Price on Reversionary Payments, vol. L 5th ed. 148 X X ^ o 4i *2 ^j ^ c o 00 — = O o s a, •- o u £ s £ «- r 3 ?: £ Cl o 01 E ^c -r 14Q 00 a c ^ g v_^ fa 3 rt O 3 "m> fa U2 bC C3 •a C A 13 'C a V S f. *s B 9 fa rt rt y ca £ s £ <* t^ «J t^ <0 *>. f->. 00 o o _l 94 S« c« c* > © t« tN. c o t^ t^ »m vC -. "* * H ■ • , a o ■ s m ■ SI • e 2 ■_ 3 D E CO C o > > "as a 1 6 a fa O O o o © • ^4 s »«•« a -ji "a? B i-5 © a - ■— - O 9 n fa ■ 5 e ~ «N fa g er ~ B t- -2 "** ^ =L a - V a fa © ■g — = © "^ ,° O rr. 2 u 3 — *5 •-- i2 c In o en r}» »"> t^. 00 Oi _ <* (— , <© 00 * "* <* ■^T T ^ u in »fl O -3 fa © — o £ "° So -= .ti .c > e •« -S u £ -§" 5. -2 i; a * -=: 151 .t! u p h w £ -2 ■a a « "5 fJ § "5 rt -c cog '" -a « ■£ ™ o « O bO rt U u 4> 'to 3 60 3 a u S O > 5 o g M a B £ .© s S "33 u CO w •i o > ^3 3 ji 1) = 3 cO — -5 M o t-l 1) Pi s M 1) ■q _3 B bO c c H ^ o c u Pi c C C3 to E £1 _>■. 5 fl B n -c rt rt ct 1° H E n 3 ,e CO u > bo u O ~rt a 5 (0 s u -5 .5 o, 2 L. ST* ■3 £ a c u rt -f rt B -e 3 ^ bo .2 E -C > CO 43 bo co r; 3 u -a 3 <-, >. t^ -0 ~ C •a -5 ►» « -O 00 o r^ s -r f s" "s !? s S« N Of O* —i >0 C?> * i> ©I Oi ^r cc Tf fO — Cf O CO 90 O O O «5 i— i 3 X 5 I-* — < 30 o .— i — « Ll. «Q ** CJ CO fN *o -* "V C?> oo i^ *0 ^ 'O ■* c< t^ t^ o -^ s ■o 1— ( cc o e>» o JO 80 SO o X -* — ' s N. CN o — o> X — O cr> Oi f^ CO o e i-^ X C! c^ t^ L^ , s C^ CO »n — < -o 2i « — * •o (^ ^< oc tN i^ 'O 30 o U3 rji •£ 2 ~z 'O t> CO CO r* rt f. ~ t 1 •+ co r^ OJ o C5 OX ?* •* c< X s - * c3 o a; O z o H s .e c y c „« ' T la Q o. i £ c 0) 1- u fc IT - £ > 4. ^ u, J3 gj >- -=s cm o «) ■Tl s o O ■£. « B e- "-3 e * 154 No. 3. TABLE XXV. RELATION OF DEATHS IN SUMMER AND WINTER, AT DIFFERENT PLACES. Period of calculation. Places. Deaths. Proportion. Summer. 1 Winter. 1 13 fears 2 Sweden . . . • 18880 20C90 lOtoll 5 I 2 Eccles, near Man Chester . •I 415 455 10—11 40 3 Bland ford . . • 617 725 10—11.8 15 4 London . . . • 122611 146^17 10—12 60 2 Vevey, Switzerland l6P7 2140 10— 12.5 •40 3 Blandford . . • 645 829 10—12.8 20 2 Gainsborough . • 590 765 10—13 6 5 Plymouth . . 1103 1446 10—13.1 5 Stockholm* . . 'Edinburgh . . • 1139 1515 10—13.3 10—13.3 9 * Manchester . ■ 1788 2427 10—13.3 9 25 country (own! in England . ] 1 5250S 66357 10—13.5 9 56 1210 10 — 13.5 3 •Chester . . . • 340 47S 10—14 8 a Warrington . • G92 96S 10—14 6 { 8 PlymouthDispen- sary .... i 69 121 10—17 . ! 1 1 US 11 Summer includes June, Tuly, August, and September; Winter includes December, January, Ftbruiry, and March. 42:22*222 Price on Rever sioiary Payments, 5th ed. ii. 270, note. S3 Phil. Trans. voL 68. In tie first instance, the deaths front smallpox are excluded. * Short's Observations. — Hebeden,4S. * Tab. XVII. completed to suyears, 1799 to 1804 inclusive. 8 Short's Observations. — Hebrden, 47. 7 White. — Heberden, 49. 8 Table XIX. * In the note above cited fom Price, the number of deaths at Stockholm are traniposed as t> the seasons ; but as this place is not sited as an exception, the suppsed error has been here corrected Printed by C. 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