T 1 3 2 1 Tr aclieo - Bronclioscopy, 190^ Esopliagoscopy and rjbevalier Jackson^ M.D* -I'll—l'^Wl THE LIBRARY OF THE UNIVERSITY OF CALIFORNIA LOS ANGELES GIFT OF SAN FRANCISCO COUNTY MEDICAL SOCIETY ./ Tracheo-Bronchoscopy, Esopnagoscopy and Gastroscopy. BY CHEVALIER JACKSON, M. D. Laryngologist to the Western Pennsylvania Hospital, tlie Eye and Ear Hospital, and the Montefiore Hospital. WITH FIVE COLORED PLATES AND MANY ILLUSTRATIONS. ST. LOUIS, MO.: THE LARYNGOSCOPE COMPANY. 1907. COPYRIGTED 1907 BY Chevalier Jackson. TO THIC Father of Bronchoscopv, Professor Gustav Killiax, as a token of esteem, this book is dedicated. \^ 6242S7 Bicnedieal Library (^07 Preface. The )«ime has L-ome when not onlv the profession hnl also the pubnc demands tliat every Iar\-ngologist shall be expert at the removal of for- eign bodies from the trachea, bron:iii, esophagus and stomach. The day has come when the treatment of diseased organs, especially chronically diseased organs, without looking at them is regarded as a groping in the. dark that i^ pennissible onl\- in organs that cannot be safely examined. The eso|)hagus has lieen for some years granted, though somewhat grudgingly, a place among the organs to be examined. The trachea and l>ronchi, owing to the initiative of Professor Gustav Killian, have been recently accorded a place also. Lastly it has been the author's privilege to demonstrate the ease with which the stomach may be examined by endoscopy. At the present time, the only available information in the English language on these subjects is the reports of cases scattered through the journals. These reports do not give working data li\' which the student mav learn how to proceed. This book is intended to furnish this informa- tion, and is not in any sense exhaustive. It is preliminary to a complete work, which the author has in preparation. While the author realizes that there are men more capable of writing on the subjects, yet. as they have not done so, this little book is offered with a full realization of its shortcomings, but also with the assurance that every assertion therein, not attributed to someone else, is the result of practical experience. Thanks are due to Dr. Jnhn W". Boyce and Dr. Ellen J. I'attersoii for aid. Chev.\lier J.\cksox. Pittsburgh. Pa.. ]\larch. 1907. Introduction. P.\- direct larvnn;oscopy is meant the direct examination of the interior of the larynx, in contradistinction to indirect laryngoscopy by which a reflected image of the larvnx is examined. Direct laryngoscopy is prac- ticed with the aid of various instruments which serve to drag out of the way the anatomical structures which ordinarily obstruct the view. By tracheo-bronchoscopy is meant the inspection of the interior of the trachea and bronchi with the aid of tubes which serve as specula, bring- ing into view successively the various passages, by pushing aside struct- ures that would obstruct the view, or dragging the passages into a new position where they will be in the direct line of vision. ^^'llen the tiilies are introduced through the natural passages, the procedure is spoken of as upper tracheo-bronchoscopy, as distinguished from lower tracheo-bronchoscopy in which the tubes are passed through a tracheotomy wound. By esophn.goscopy is meant the inspection of the interior of the esoph- agus with the aid of long tubes which serve as specula. It is almost al- ways practiced through the natural passages. By gastroscopv is meant the inspection of the interior of the stomach by means of tubes wdiich serve as specula. It is usually practiced through the natural passages, though it is occasionally done through an abdominal wound or fistula. Contents Part I. tuaciii-:ii-i:ronchoscoi*y. Chapter I. Historical Xdtes. Cliapter II. Jnstruniciits. Chapter III. Acquiring Skill. Chapter I\'. Technic. Chapter \'. Direct Laryngoscopy. Chapter \1. Anatomy of the Tracheo-bronichial Tree, Topographi- cally. Radiographically and Endoscopicallv Consid- ered. Chapter ATI. Tracheo-briinchiiscoi)y in Diseases of the Trachea and Bronchi. Chapter A III. Tracheo-bronchoscopy Upper and Lower, for the Di- agnosis and Extraction of Foreign Ilodies. Part II. ESOPHAGOSCOrV. lntr( iduction. .\natomical Notes on the Esophagus. Xormal Esophagoscopic Appearances. Technic of Esophagoscopy. Diseases and Anomalies of the Esophagus. Stenotic Diseases of the Esophagus. Acute Inflammations. Cicatricial Stenoses. Neoplastic Stenoses. Spastic Stenoses. Compression Stenoses. Chapter XV. Non-Stenotic Diseases of the Esophagus. Diverticula. Diffuse Dilatations. Chapter IX. Chapter X. Chapter XL Qiapter NIL Chapter XIII. Chapter XIV. COXTEXTS— Continued. Tntlanmiations and Ulceration?. Paralyses and Pareses. Neuroses. Chapter XVI. Foreign Bodies in the Esophagus. Part III. GASTROSCOPY. Chapter X\'II. History. Chapter X\'III. Usefulness of Gastroscopy. Chapter XIX. Instruments for Gastroscopy. Chapter XX. Technic of Gastroscopy. Chapter XXI. Area of the Stomach Explorable by Gastroscopy. Chapter XXII. Difikulties, Dangers and Contraindications. Giapter XXIII. Gastroscopic Appearances. Part I CHAPTER I. Historical Notes. Bozini in 1807 examined the npper end of the esophagus. \'oltolini and Waldenberg, in i860, and Stocrck, in 1861, devised esophageal spccida iisini;- the laryngeal mirror. Kussmaul, in 1868, did the first esophagoscopy worthy of the name, using a Desormeaux urethroscope elongated to 43 cm. He diagnosticated a carcinoma of the thoracic esophagus and approache) hav- ing a drainage tube made in its wall which maintains the lield of observa- tion, clean and free from secretion, and prevents the necessity for interrup- I''lG. 7. — AiiUior's separable speculum for passing tironchoscopes. Handle. A B. is onl.v used on tlie sitting patient. tion for the patient to expectorate, the constant desire to do which is the source of more discomfort to the patient than any other part of direct lar- yngoscopy. For the introduction of tubes he uses a split spatula pat- terned after the ingenious device of Killian. but having it separable in the other direction, so as to avoid wounding the mucosa. (Fig. 7) It is made in two forms, one is self-illuminated, the other is not. 20 INSTRUMENTS Fig. S. — .Mikulicz's psophagosoope, maudrin aud (ui'.\t to bottojii) "practice liougio." Tlic liandle portion i.-. a Caspar liandlamp. Fig. 0. — Rosenheim".s esophagoscope. mandrin forceps and cotton liolder. IXSTKL'MBXTS. ■n 1 U„rv-linped hou.^ie. li. Tube with mandrin in place. :'.. ( ottou holdeu 4 1. lM)i.\ uppeci )oi.„ii i„i„rerl curette S, !>. li>. H. Fofceps :a\vs. and 7. Forceps. 5. Forceps handle. (,. .Jointed curette. ., 12. Leiter's paneloctroscope attached to luhe. 10 II 12 '3 I" 7 8 9 10 II I il ^0 ^R ^^B ^^^ ^^^ ^^n .••■jmwiiwt^**'^"*""^' forcep. for removal of specimens. S. Coiuaatel toiop. 10 to IC. Sounds and foreign body hooks. 1.. (ott.m lu.ld.i. 99 TUBES. Mikiilic", whose work is mainly esophageal, uses straight metallic tubes, the distal ends of which are cut off slantingly. (Fig. 8.) They are fitted with a mandrin tipped with a soft rubber pilot. Tlie inside of the tube is Ijlackened to prevent annoying roHections. For illumination he uses the Casper handlamp. Rosciihciiii uses a similar tube and illuminalnr. (Fig. 9.) J'oii Hacker for the esophagus uses a similar tube but uses the Leiter panelectroscope, a half open cylindroid box with mirrors. (Fig. 10.) Fio 11'. — Killian"^; bronclioscope and (below) Kirstein's esophagoscope with wiiuliiw. Starck's esophageal tubes, shown in h'igure 11, have no fitted man- drin, a form of esophageal sound being used as a pilot. Kil Han's tubes (Fig. 12) are designed especially for the trachea and bronchi, the svstematic exploration of which dates from Killian"s original demonstrations. He uses straight rigid tubes of plated copper, graduated in centimeters outside, and highly polished inside. They all fit into a uni- versal handle. (Fig. 13.) The sizes of Killian's tubes for bronchoscopy Fig. 33. — Uuiversal handle to fit Killian's tubes. to be had in the shops vary from 7 to 9 mm. in diameter and 14 to 52 cm. long. For esophagoscopy the sizes are from ii to 13 mm. in diameter, and from 19 to 52 cm. long. Including both esophagoscopes and bron- choscopes 18 sizes are listed, besides the 6 tubular spatulje. All of these are not essential, but for the best work and to be prepared to meet all emergencies, the largest possible assortment should be on hand, so that the tube of shortest length and largest diameter possible may be used, for the technical difficidties varv inverseh' to the size. TUBES. 23 Killian uses the Kirsk'in lK'a(ll:iiii|) fur ilkiminatidn. X'on SchrrittiT designed a bronchoscope (Fig-. 14) the chief advantage of which is that the tubes fit in a universal handle, so that after passing a second tulje through the first, the handle may be removed fmm the first and attached to the second and thus onl\ one handle is in use at a time. Fig. 14. — von Sohrijtter's hrouclioscope. A. Bi'oiiclioseii|iic tube. B. Dotacliable liantlle. which can he removed, leaving onl.v the c.vlimlrical part of tlie tuhe and attaclied to a second tube passed throngh tlie lirst. Einhorn's esophagoscope (Fig. 15) consists of a straight tube without lip or ring or thickening at the distal end. In the wall of the tube is made a small auxiliary tube in which a light carrier is inserted, carrying the light to the distal end of the instrument. A mandrin locked by a pin is fitted, presenting a conical end for insertion. Fii;. 1."). — Kiuhorn's esophago.scope and mandrin. Ingals uses a Killian tube in which he inserts a little lamp on a light carrier (Fig. 16), removing the light carrier before he inserts a mop or a forceps. Tlie light being removed, the forceps are inserted, and the foreign body or specimen is seized by the sense of touch and the memory 24 TUBUS. of its pDsitinii, ilic depth (if insertion licinn;- known liv liavin,^;- a provionsly placc(l mark, as h\ a niljljer hand, on the forceps shank, showing the length of the particular tnbe used. The author's tubes (Fig. 17) are ilUiniinated liy a small "cold" lamp carried down to the extremity by a light carrier. The chief advantages of this form of illumination are these: I. The light being in the tube is always illuminating the object, re- .gardless of the movements of patient or operati ir. I'or this reason. i)rolonged practice, as with the headlamps and unil- J''i(;. IG. — Ir.sals' lirouehoscope. A. Killiau liilit. B. Iiii^als' light ciirrier. luminated tulies. is not necessary. True, the lamp occasionally gets smeared with blood, but it requires no more time to withdraw the light carrier and clean the lamp than it does to clean off the mirror or lenses of a head- lamp which are Ijcdaubed every tinue the patient coughs, and when thus bedaulx'd the light is dimmed. The constant readjustment of a headlamp consumes nuich time, as each time a piece of sterile gauze nuist be picked up to handle it with in order not to infect the hands. 2. There is no urgent need of selecting the shortest ])Ossible tube. Tlie illumination is as good and the \'iew as good through an 80 cm. gas- T" FUi. 17 Author's bruiichoscopc. csoiiliagoscope au , clean condition at the distal end oi the tube. Occasionallv a tube is needed without this auxiliary drainage, but oul\- l-'u.. LS. — Antlior's secrftiou-:\s|iii;ilcir. rarely, as in case of passing a narrow stricture. The secretion is pumped out by the negative pressure maintained in the bottle with the aspirating syringe (Fig. 18), the rubber tubing connected with the bottle being slipped over the outlet of tlie drainage canal. Should the drainage canal become obstructed, which very rarely happens, an extra drainage tube is run in and out as needed, being connectable to the same asjiirator. These extra drainage tubes are useful for blowing in medicaments or bismuth oxide for Roentgen rav localization, b'or bronchoscopy drainage is not often necessary. ACCKSSORV INSTKCMENTS. Forccf^s. The forceps of Coolidge ( Fig. 19) are exceedingly satis- factory. The tube is pushed over the jaws by a trigger action and the large handle will be very convenient to most operators. Starck's forceps (Fig. 11) are actuated by pushing a thumb Initton and are good. 26 FORCEPS. Fig. lU. — C'ooliilge's forceps Fig. 20. — Killian's toiveps antl manner of holding it. Fio. 21. — Killian's .stronger forceps anil varions .iaws, tlie threatled one being an expanding form for the extraction of hollow foreign bodies. FORCIiPS. 2( Kalian's forceps (Fig. 20) are made in t\\ i styles of mechanism and Will be found to do their' work ijerfectly. The) arc excecdino-ly conven- ient to those accnstomcd to the tin,L;er-lever aclinn >>\ Dr. .Mnrrcll .Macken- zie. A stronger pattern is shown in 1-ig. 21. G:==C I-'K,. 2"-!. — Aiitlior's forceps. The author's in-eference is for tlie light, convenient, ringed handle (Fig. 22) we are all so much accustomed to manipulate in the hemostat. The'tuhe is pushed over the jaws, the jaws are n..t drawn into the tube. ''■'>5!!^ r-'iG. 2o. — Author's I'orci'iis, oiu-vimI .i,T\\> the thus they do not retreat from their bite. As with all tube torceps, strength of grip of this instrument is astonishmg. Different lengths of canuhe and ''differently formed jaws are made to fit one handle. The !''«:. 24.— Aiillior's forrcps. ciippiil .jaws. form shown in h'lgure 27, is for going down alongside a |iin or ncedl.- and grasping it sidewise, or reaching around a turn or bend, or sidewise past the end of the tube. Tliese are also made with cupped extremities like Fig. 24, for the biting out of a specimen laterally from a wall. Either cup- ped or serrated they will b.' found exceedingly useful for biting off a pa- 28 ACCESSORY IXSTRCMHXTS. jiillciiiia or other neoj)lasin from the anterior commissure of the larynx, and similar jnirposcs. as will also the pimch forceps (Fig. 25). Cotton carriers with roughened ends are too uncertain. It is ainioy- ing to have the di>ssil slip off. and still more so is the delay occasionally necessary for a prolonged search for it. Mikulicz has devised a very in- genious claw end to hold the cotton. Coolidge uses the most comfortably i'J(j U-j. — Author's forceps, rinicli jaws for excision of a speciun'ii. U'lie lower instrument is a tent carrier to work in forceps liaudle. safe device (Fig. 26). The slip collar screws down on the spring jaws so that thoy cannot lose the dossil. The author uses these exclusively for bronchoscopic work, though for the esophagus and stomach where there is no risk from, or delay in removing, the lost mop, the author uses the simple slide which does not screw, small gauze sponges being used instead of cotton, which is pront soiisa Fig. iMj. — Coolidae's cotton lioliler. to leave threads that interfere with vision. About a dozen carriers are needful for rajiid work. ( )f the other accessory instruments, various hooks, probes, etc., are useful. Alosher has devised a most ingeniou.= safety pin closer (Fig. 2j). It consists of a ring which is passed clown below the open pin ; then the pin Flc. 27. — Moslier's safet.v |)iu closer. is pushed in spring-end first by the little pronged instrument. To facili- tate passing the ring below the pin, the author has arranged a stem that permits of introducing the instrument with the ring in the same plane as the stem. ,\fter the ring has passed the pin, moving the handle turns the ring to a right angle with the stem. ( Fig. 28. ) For endolarvngeal surgerv, such as the incision of edematous masses, Acciissni^y ixsriu witixis. •29 (lixisimi of stenotic webs, openinj;' of abscesses, ami similar work it will be found necessary to bave at least one knife. (Fitj. 29.) A mouth g-ag is a most important accessory, b'ergusou's (Fig. 30) has given tbe author most satisfaction. .\ long cleanins.'' wire for the >'■-,' \ ^■> Flu. 1!^. — Till? aiitliur's safety piu clustT. canals, extra lamps, sterile vaseline, small gauze strips about 4x6 cm. in size and folded into sponges, a steel centimeter rule and battery complete tbe outfit. Comiuercial lighting circtiits should never lie used iVir lighting the Fig. -'•). — Aiuliur's lar.vii;;i'al kiiifi'. lamps. .Ml rheostats ha.vc one live side which may be "grounded" tlirrmgh the patient, involvmg great danger, even if of no more than no volts pressure, on account of the good contact with the moist mucosa, through- out the length, of the tube. Dry batteries (Fig. 31 ) involve no risk what- FlG. .30. — Fersiisou's moutli sas. ever and with intelligent care are perfectU" satisfactory. The box should have a rheostat for regulation of the current. If much work is to be done a storage battery (Fig. 32') will be found conveniuit. 30 BATTERIES. If the operator does not wear g-lasses habitually, it will be necessary to have spectacles with plain eyes of larsje size for the prevention of infec- KiG. ol. — Eight-cell dry battery for euilnsidijy. Fig. o2. — Four-cell storage battery for eudoscopy. tion from coughed out secretions, which shoot out like projectiles from the tubes. A list of instruments is here appended for convenience: LIST ()/•■ IXSTRL'MHXrS. 31 LIST OF TXSTR^^[F.^■TS. TUBICS. The author's tubes are made in the following sizes: lo mm. X 53 cm. eso|)hagoscopc for adults. 7 " >^45 ' children. 7 " X40 • bronchosco])c adults. 8 " X 20 ' ' tracheoscope adults. 5 •' X 14 ' . It children. 5 •■ X30 ■ bronchoscope adults. 5 ■■■' >^45 • i t> children. 12 ■' X 17 ' ■ tubular specul luni. 12 ■■ X f7 • separable for adults 10 " X70 ■ S'astroscope for adults. If rigid economy nnist be practiced, much good work can be done with a 7 mm. x 45 cm. esophagoscope, a 5 mm. x 30 cm. bronchoscope, and a 12 mm. X 17 cm. separable speculum. The 7 mm. x 45 cm. esophago- scope can be used in the adult trachea and main bronchi, but if used in the latter, the absence of lateral openings must be remembered. Lateral open- ings are a disadvantage in an esophagoscope. He who expects to work- to the best advantage with any and every case encountered will need the entire set. For bronchosco])y tubes with drainage are not often needed. The diameters of the tubes as here given are of the cylindrical tubes before the canals are uiade in the walls. These canals bulge outward slightly, thus increasing one diameter, though this need not be taken into account as the resiliency of the passages more than compensates for it. Killian"s tubes are made in the following sizes : For bronchoscopy, adults 9 mm. x 18 cm. " " 9 ' ■ X25 ii 9 " 9 ' children 7 ' " >;35 " X41 ' >^ 13 ^t ( 7 " x 18 n ti a 7 7 " X23 " x28 esophagoscopy adults 7 1 1 " X35 • X19 *' II " X32 C4 •' 1 1 " -^45 (( a II " X52 a a 13 " X19 it a 13 " X 24 it ti ti a 13 13 " X32 " X42 t ( a 13 " X52 32 .-ICCRSSORIHS. For esoj)hagoscopy in children the y mm. bronchoscopes are used. One universal handle for all tubes. Tube spatulas, three sizes. Tube spatulre, split, three sizes. The following list of accessories will be found to contain the essen- tials : ACCESSORIES. Aspirator and tuljing". 3 mm. X ()0 mm. extra drainage tube. 3 ■■ >^40 4 •■ x84 ' I forceps 25 cm. canula and 4 jaws. I ■■ .VS 4 " I " 60 " ■' ■■ 4 " I " 84 4 " yi doz. sponge holders 2^ cm. long. i^ '• •■' •• 66 ■' ■' I " •• ■■ 84 " " I hook and probe 25 cm. long. I " '• ()0 '■ I ■■ •• 84 •■ " I Lister-Killian hook 23 cm. long. I '■ ■■ '■ 60 ■■ I •' •• " 84 " " I safetv pin closer, 3 mm. ring, 30 cm. long. I "■' •• •■ 10 •■ •■' 60 •■ " I Sajous laryngeal sponge forceps, (curved) I .Laryngeal knife. I ■' cautery electrode and cord. 1 " galvanic electrode (monopolar) and cord. y2 doz. extra lamps. 2 wires for cleaning canals. I sterilizing tube for packing sterilized extra lamps. Eye glasses for the protection of operator's eyes. I double bronchoscopic battery and conducting cords. I extra battery cord. CHAPTER III. Acquiring 5i<:ill. As bronchoscdin- with the avera,c:e laryngologist or surgeon is rela- tivelv a rare procedure, some prehminary practice is advisable. If Killian tubes with the Kirstein headhght are used considerable preliminary train- ing will be necessary to keep the light projx'rly directed down the lube, and the general physician or surgeon, who has had no experience whatever with even the ordinary head mirror, will find that long preliminary prac- tice is necessary in order to see anything. With the distally illuminated tubes anyone can see clearly. line author has frequently had physicians totally unfamiliar with tube work, discuss appearances at their first exami- nation in a way that revealed the fact that they had obtained good clear views. Nevertheless, some practice is, of course, necessary. Endoscopy is in no case like looking through an opera glass. Many details require attention. Lights are to be cleaned and readjusted, secretions to be con- tended with, cough and reflexes to be combatted. The first step should be the technical management of the miniature electric lights and the batteries. If possible, this should be acquired by instruction. If not possible, the details may be worked out by experiment. After burning out a few lamps, the current strength they will stand is soon learned. If too strong it will shorten the life of the lamp even if it does not immediately burn it out. All lamps, whether used in tubes or on head- lamps, must be adjusted by watching the filament. It will never do to start using the tube and then run up the rheostat until the ojierator thinks he is getting enough light on the object. This will mean no end of trouble. Every lamp will stand just so much, and no more. This amount gives what is called full illumination. It is not easy to describe, further than to say that it is the point where the filament seems to grow thicker and turn white, just beginning to lose the yellow. \\'hen first commencing to glow, it is red. As the rheostat is run up, it turns to yellow, and then to white. \\'hen just commencing to turn white is the point of full illumination. 34 TESTING LIGHTS. If pushed to intense dazzling whiteness, it is overilluminated and will soon burn out ; while if only yellow, with the filament plainly visible, it is underilluminated and useless. Until this is thoroughly mastered, it is use- less to attempt endoscopy. Many utter failures have been due to rushing into endoscopv on the living without a full mastery of the purely mechani- cal details of the instruments. Some practical experience in the location of electrical troubles is ex- ceedingly useful and can only be acquired b}' practical experience with elec- trical api^aratus. An automobile ignition experience may help. A skill- ful experienced operator will quickly locate the cause of "no light" where the inexperienced will give uji in despair. All electrical apparatus turned out for medical work, including that for endoscopv is too flimsv. The wires are too fine, the switches and rheostats too delicate. Of course, even if perfect in construction, wear and also damage by transportation, rough handling, sterilization, and other things will cause broken circuits, short circuits, and "no light." The best way is to have a definite routine for locating trouble. The following order is a good one: 1. See if your switch is on and the rheostat where it ought to be, pressing the levers to see if they have sprung away from contact. 2. Test all contacts and connections by screwing home the lamp, twisting the bayonet catch, screwing down the thumb nuts on the binding posts. 3. Next try a new light carrier that lighted uy ])ro])erly before. If this lights u[), the trouble is in the previously used light carrier or lamp, which of the two being quickly located by trying a new lamp. If the light carrier which worked perfectly before, fails to light up, trv a new cord, or if this is not at hand, close the circuit from one binding post to the other through the light carrier. If at any time, the light flashes on again, note where you were touch- ing the apparatus at the time, as there is likely a loose connection at the point, brought into contact by your touch. These tletails are soon learned and are necessary with any endoscopic apparatus, unless an electrician be available in the operating room. The location of "no light" troubles with the Ivirstein headlamp is much the same. First, see if the current is on by turning on one of the room illuminating lamps. Tlien test the Kirstein lamp to see if it is screw- ed home, or, if the glass looks blackened on its interior surface, trv a new one. Next, test the cord as before described, then the switch, then the binding posts and rheostat. Usually the commercial lighting circuit is used, and rheostats for this purpose as made at the present day are flimsy and subject to constant disorder. Two or more are necessary as at least one will be always at the factory for repairs. Tliere is no need for Ibis to .icurih'ixa SKILL. 85 be the case, but such seems to be the condition of meiiico-electrical nianu- faeturing to-day. Doubtless there would be less trouble, too, if physi- cians were better skilled in electrical mechanics. After the details of batteries and lights have been mastered some fa- miliarity with the manii)ulations may be gained from tubal exaiuinations of the interior of the clenched fist, pushing the tube ilnwii ihrnugh it from the upper (radial) side. The rubber manikin of Killian (big. S3) is '^■^"''}' "seful for i)r;ictice, being ingeniously designed to sinudate actual obstacles to the intn.KJuction 1' IG. ;!3. — Killiau's niniiikia for practiuin^' lii-ouchoscnpy anil esophagoscopy. of a tube through the natural passages. The dog offers a convenient ani- mal subject for ]nactice. Chloretone hypodermaticallv in doses of I gramme is a convenient anesthetic for the dog. The author's preference is for scopolamine gr. i/ioo (0.00065 gm-) with morphin gr. 1/2 (0.0324 gm.) given hypodermatically one hour before, and repeated, if there be no signs of oncoming stupor, twenty minutes before the time for practice. 36 .-ICOUIRIXG SKILL. Much available material is wasted about the average clinic. Cases of gfoitre that complain of dys]jnoea, justify tracheoscopy, and any case of goitre which by its size demands o])eration should be tracheoscopized for tlie information yielded. Cases complaining of difficulty in swallowing are neglected or sent to the general medical or gastro-enterologic clinic, when in reality it is the plain duty of the laryngologist to find out by direct laryngoscopy, and by esophagoscopy idiy they cannot swallow. Patients wearing tracheal canulse would be the better for a tracheoscopic watcii upon their endotracheal condition. Mucosal inflammations and ulcera- tions, perichrondrial and chondrial diseases could be detected and cured. A]\ this material is at the present writing wasted in all the clinics of this country, to say nothing of the neglect of the patients' best interests. CHAPTER IV. Technic of Direct Laryngoscopy and Tracheo- bronchoscopy. General Considerations. Asepsis. It cannot be too strongly emphasized that the strictest de- tails of aseptic technic must be followed out. Tliis will limit infective risks to those organisms already present in the mucosa. If this be not (lone, sooner or later, the operator will have upon his conscience the bur- den of having inoculated a fellow creature with syphilis. di])htheria. ery- sipelas, tuberculosis or other infection. In regard to the field of operation, absolute asepsis is impossible, but the mouth, the most septic portion of the tract, can be put in a relatively clean condition. A definiti; routine position, of all tallies, instruments, liatteries, assist- ants and nurses should be followed, otherwise all is confusion, which is not conducive to good work. Ouiet, orderly ])roc.?dure is essential. Sterile caps should be worn as well as gowns, to {)revent infection of instruments in passing them to and fro, especially the long instruments, particularly when an assistant or the operator stoops, kneels or sits. llie patient is clothed in a sterile gown if the sitting [josture is used; or covered with the usual sterile sheet and towels if examined in dorsal decubitus. Either way he should wear a sterile rubber cap pulled well down over the ears. StcriIi.':aflon. All instruments except the light carriers, battery cords and aspirator can be boiled. The light carriers should be immersed in alcohol before using and a stock of lamps already sterilized shoufd be packed in glass sterilizing tubes. The battery cords are rubber covered so they can be wiped with mercuric bichloride solution. The a.spirator is immersed in 5 ])er cent, carbolic acid solution, which is also pumi)ed through it a luimlier of times. It is then rinsed in sterile water. 38 BRONCHOSCOPY. If, during the course of an upper bronchoscopy, it is decided to do a lower bronchoscopy, everything should be resterihzed before opening the trachea, provided there is time. Sterile tracheotomy instruments should be at hand on a separate table where they will not get soiled while work- ing with the bronchoscopes through the mouth, and where they are reail}' for immediate use. If, as will occasionally happen, an immediate trach- eotomy is required, it is an advantage to have an assistant who has not been contaminated with the mouth, or the instruments used therein, to stab the trachea. In any case there will be ample time to resterilize all tracheo-bronchoscopic instruments before introducing them into the trachea, and it is utterly unjustifiable except in dire emergency to intro- duce through a tracheotomy wound, the instruments soiled in the mouth. It may be argued that in upper bronchoscopy the tubes are introduced through the mouth, but they are introduced through a split spatula and no great amount of infective material need be carried downward. Besides, one great advantage of lower bronchoscopy is its asepsis, and this advan- tage will be lost if instruments infected in the mouth be used without re- sterilization. During an examination the small lights require cleansing frequently, the light carrier being withdrawn for the purpo:-e. \\ ith trained help this requires but a moment. Occasionally it will be found that the ciu'rent requirements of the lamps vary, and a little readjustment of the rheostat is necessary for a fresh lamp. For rapid work, it is imperativelv necessary to have a trained assistant who is thoroughly familiar with all the appara- tus, and also a nurse who is trained to keep the lamps and tubes clean and in good order while working, so that the operator has nothing to do but to observe, while armed sponge holders, forceps, probes, hooks, fresh light carriers with lights properly illuminated are handed to him as called for. A stock of extra miniature lamps should be kept sterile, packed in glass sterilizing tubes with a wad of cotton between each lamp, so that a single extra lamp can be taken out when needed without infecting the others more deeply placed. In this way the extra lamps are always ready and never need sterilizing but the once. Unilluminated tubes should never be boiled as boiling soon dulls the brilliancy of their interior polish. Preparation of the patient. Foreign body cases will often be dealt with without pre]5aration of the patient. Where there is time, as there usuallv is in most other cases, and in many foreign body cases, it is best to insist upon proper preparation. A purge should be given, and no food allowed for 6 hours for tracheo-bronchoscopy. 8 hours for esophagos- copy and 12 hours for gastroscopy. Even in direct laryngoscopy the pres- ence of the instrument in the pharynx may excite vomiting if there be food DIRECT LARYXGOSCOPy. 39 in the stomach. The possiljlc need for general anesthesia also renders fasting- necessary in a Ux-ally anesthetized case. If the patient has just eaten.and delay is inadvisable, lavage of the stomach is called for. The nearest approach to oral asepsis is imperative. Whenever practi- cable the teeth should be put in the best of condition by the dentist. The patient is then, directed to brush his teeth with soap and chalk and to rinse his mouth every two hours with thirty per cent alcohol. As shown recently by Dr. A. \\'adsworth. alcohol is the most efficient oral antiseptic. A more eligible preparation, as advocated by Wadsworth, is made bv adding sodium bicarlx>nate and chloride in normal salt propor- tions and spirits of chloroform and oil of wintergreen as flavoring to the alcohol. The patient should wash his face thoroughly with soajj and water, be- mg particularlv thorough with beard or mustache if he have these ; and he should rinse first with water and then with i :iooo perchloride of mercur_\- sohition. DIRRCT L.VRYNGOSCOPY. Anesthesia. For ordinary routine work either in the consulting room or in the operating room, local anesthesia is sufficient. A 4 per cent Fn;. 34. — Sajous' cotton liolilins forcin» for prelimhinr.v oocainizntioii of the larynx and pliar.vnx. solution of cocain is applied w ith a mop of cotton held in the Sajous for- ceps (Fig. 34). After waiting a few moments, the laryngeal speculum (Fig. 6) is introduced until the epiglottis appears and a more accurate apphcation is made to the epiglottis and all tissues in its neighborhood. Then the instrument is passed posteriorly to the epiglottis, bringing into view the interior of the larynx and the introitus esophagi, which are swept over with a 20 per cent solution. Cotton mops may be used for this. For operative work, where there is no dyspnoea, a general anesthetic should be used, as the relaxation and absence of tetanic reflexes renders the examination very nnich easier. It is not painful, though a spectator would not believe this, as in many instances the patient looks as if he were chok- ing to death. Cocain must he used cautiouslv in children. 40 TECHNIC If a general anesthetic be used, chloroform is preferable; being con- tinued, after the examination starts, by a gauze sponge held with a hem- ostat and saturated with chloroform. This is held over the mouth and nostrils, or, if the jiatient has been tracheotomized, over the tracheotomy wound. Direct laryiii/oscol^y. Patient sittiiu/. For ordinary routine direct lar- yngoscopy in the consulting ro(^m, the patient sits upon a low stool, the assistant sits on a higher stool or stands behind the patient and holds the gag and the head an' ASSISTANT ^ INSTRUMENl TABLE l-'io. .^0. — Direct lar.vngo.s(:oi).v. I'atient sitting. iJiasrain of posilions of jktsous and liiiiigs. Table slionld be a little nearer the operator. is used she may work this, or it may be done by the second nurse. If but one nurse is to be had, a good supply of sponge-holders is needed. In looking at Fig. 37 the table would be the foreground, with the nurse to the right, and the first assistant to the left, as seen in the diagram Fig. 36. The duties of the second assistant are extremely important. He must liold the patient's head bent backward, with the trunk, and especially the neck pushed forward, the bend being as much as possible in the region of the axis and adjacent cervical vertebrae. At the same time he holds the mouth widely open with the gag, and in a case of a sitting patient, with the forefinger he keeps the patient's upper lip away from the upper teeth. 42 USE OF LARYNGEAL SPECULUM. He should realize the importance of his duties, and that a cut upper liji means the most reprehensible carelessness upon his part. All of the details as here given are not absolutely necessary for the brief examination in the consulting room ; but for more prolonged exami- nations, removal of foreign bodies, and certainly for all operative proced- ures attention to all the details given is absolutely essential, as already mentioned, for good work. Using the laryngeal speenhiui. The light on head lani]) or light car- rier having been adjusted to the proper brilliancy, and the field being an- esthetized, the tubular speculum is inserted until the epiglottis appears in view. The flat end of the tube is passed behind the epiglottis about a I'll;. '.1. Liiwur traclit'o-broiicliosciipy. I'atirut siltiiij;. centimeter, and now comes the only point where difficulty in the manipula- tion is encountered. Once this knack is acquired, no difificult}- will be met with. The epiglottis must be pushed forward tightly against the base of the tongue, which, with the tissues attached to the hyoid bone, must be forcibly pushed forward out of the line of vision. This pushing is done with the spatular extremity, the directioii of motion being shown schemat- ically in Fig. 38. The instrument is given a forward motion of the tip by an upward and backward motion of the handle, the pivotal point bemg at the junction of handle and tube. By this it is not meant that the tube rests on the upper teeth. This is the first and most serious error made bv Tf.CHNIC. 43 the iiu'xp.Ticnccl. li is mtcrly impossible to get a good. view, of the laryii.x if the upp-''- t^^'th are used as a fulcrum to pry the mouth open and the hyoid tissues forward, and the strength required is painfully great for both patient and operator. Another error frequently ronnnitted by the inexperienced is the inser- tion of the speculum too deeply, so that it gets behind the cricoid cartilage. This is evidenced h\ interference with the patient's breathing, by the open- ing up of the upper end of the csojihagus to view and resistance to the for- ward pressure of the tip of the mstrument. Under these circumstances, when the specuUnn is withdrawn slightly the "brassy" tubular respiratory sound denotes the right place. One soon learns to tell by the sound when tubes are at the laryngeal orifice. Upper tmcheo-bronchoscopy. Silting posture. If desired, as in se- vere dvspnoea. the bronchoscope may be passed with the patient seated. j.'iQ 38.— Diagrammatic represeutation of direct laryngoscopy and scliema. sbow- iug dh-ection of force applied in usiug llie tubular speculum and separable spatula. The split tubular speculum is used and the bronchoscope passed as shown in Fig. 39, which, however, shows the first assistant in the wrong position, the correct one being as in Figs. 36 and 37. Hie technic is the same as described for the recumbent posture. The author prefers the latter post- ure for bronchoscopy and he would tracheotomize patients too dyspnoeic to lie down without it Should tracheotomy be demanded, it is an advan- tage for the patient to be already recumbent upon the tal)le. \Mien a gen- eral anesthetic is used recumbency is imperative. Fig. 39 .shows left upper bronchoscopy, the split tubular spatula in the right buccal angle, the bron- choscope passed througli the tubular spatula which has not yet been re- moved. The second assistant holds the gag in the right side of the pa- tient's mouth, while with his left forefinger he elevates tb.e patient's upper lip at the left side (removed when the photograph was taken so as not to hide the instruments). 44 TRACHEO-BROXCHOSCOPy. Fii;. '.i'J. — \jnit u\)\)vv iracliHu-brimsfUoscopy. Patient >ittiLig. First assistant's position should be as shown in Figs. 30 and 37. Fid. 40. — Left upper tracheo-bronchoscopy, showing the introduction of broncho- scope through the separable speculum. TRACHF.O-BRONCHOSCOPY. 45 Urwcv tyachco-bronchoscofx. Stttuui tosturc. ( Fis,'. 37- I This also is not advisable for prolonged work, hut it is perfectly feasible. It is a ..reat convenience and should always he used in one class of cases : namely, walking cases wearing tracheal eanuUe. A close watch should be kept on these cases, for tjranulations, ulcers, et cetera, in the trachea. I lus is easily and quicklv done with a short tracheoscope, which is nu.ch better than anv form of dilator tor even the deeper parts of the wound, wlule for the trachea itself it is the only wav that ulcers, granulations, etc.. may be treated and cicatrices and stenotic webs prevented. Shenild dyspnoea supervene when the tracheal caiuila is removed, a quick inserti..n ot the tracheoscope will give instant relief. If previously tracheotomized the bn.nchi may be examined in this wav Of course in patients just tracheotomized. the recumbent posture is used and the author prefers recumbency in all cases, Direct laryu^oscotx. dorsal decubitus. The chief differences between direct larvngosccipN- with the patient in the sitting and dorsally decumbent positions.' are in the arrangement of nurses, assistants and operating room detail and in the manner of grasping the tubular speculum. The operating room arrangement is the same as described in the following pages under "Upper tracheo-bronchoscopy." The manner of making pressure with the tube does not differ so far as the relation of tube to the patient's anatomy is concerned. The tubular spatula is grasped f^rmlv in the operator's left hand, as shown in Fig. 40, and the motion .shown in the schema ( Fig. 38) is imparte.l to it, as if to lift the patient off the table with the tip of the speculum, or as if to force the epiglottis out between the hyoid bone and the thyroid cartilage with the tip of the speculum. Care must be taken to avoid mistaking the infe- rior constrictor, or a glosso-epiglottic fold for the epiglottis. UPPER TR.VCHF.O-BRONCHOSCOPV, DORSAL DKCIJBITUS. Posture and oilier detaUs. The patient lies upon an operating table, the foot of which is 15 inches lower than the head. The table shown in the figure 40 was designed by the author for this and other throat work. It is pivoted horizontally in the center so that it balances and no matter how heavv the patient, it is easily raised or lowered. The headlioard is only dropped after the second assistant is ready to support the head. Most tables have a dropping headboard of this kind, but if not the patient must be moved until his shoulders slightly overhang the edge of the table. \\''hen everything is ready, lights regulated, tubes greased, sponge-holders armed, assistants in position, the headboard is dropped and the patient's head is in the air free to move in every direction (Fig. 40) under the con- 46 TRACHEO-BRONCHOSCOPY. trol of the second assistant, who (in left upper bronchoscopy) sits upon a high stool on the right side of the patient, his right arm back of the pa- tient's neck, holding the gag in the left side of the patient's mouth, while his left hand supports and controls the patient's head from underneath, the hand resting upon his (the assistant's) knee, which is elevated to the proper height by a footstool or by crossing one knee over the other, de- pending upon the height of the table. In this position the second assistant can do his duty without undue fatigue during a prolonged search or opera- tion. As before stated, the second assistant is the most important factor in the work. His work is fatiguing and he should be made as comfort- able as possible. The holding of the gag is a thing that few men ever do correctly. The best gag is Ferguson's, and it must be placed on the canine or lateral incisor teeth, not back on the molars, where it is sure to slip. It NURSE STRUMENT TABLE I'.' ASSISTANT OPERMOR :V ASSISTANT j ^ OPERATING TABLE ane:sthetist Fi(i. 41. — Direct laryugoscopy. tiMrlii'ij-ljnmi-hoscuii.v. esopliagoscopy. gastro.'iooiiy. Patiei.l itoi'mbent. is placed on the side of the mouth opposite to that through which the tube is passed. In order to take the jihotograph tlie operating room arrangement was disturbed. It is shown diagrammatically in Fig. 41, and it is very essential that this arrangement be strictly follov\'ed, otherwise all will b^chaos with the long instruments needed in upper tracheo-bronchoscopy. The duty of the first assistant is to pass instruments, always in position for insertion. The nurse works the aspirator, refills sponge -holders, and cleans the in- struments. ANESTHESIA. 47 The anesthetist stands upon the left side of the patient and wlicther giving the anesthetic or not. must keep the hp of the patient away from the edge of the teeth with the loft forefinger. This duty cannot he performed hv the second assistant with a recumbent patient. Anesthesia. The examination of the bronchi is perfectly feasible un- der cocain anesthesia. especiall\- if a large dose of morphin be given: the morphin adding courage, rather than anestliesia : but except in dysp- noeic cases the author prefers chloroform, and in any case he considers morphin, with its prolonged alx>lition of the cough reflex unsafe. The cough reflex is the watch-guard of the lungs, by which infective or dele- terious materials are removed. Cocain is first applied as described when writing of direct laryn- goscopv. After the glottis is passed, the tracheal antl bronchial mucosa are anesthetized a portion at a time in stages as the tulx^ is advanced, using cotton, or as the author prefers, gauze, sponges. Chloroform is given in the usual way on an Esmarch i'.ihaler until the patient is fullv under its influence. Then the split spatu'.a is inserted and the lar>nx is mopped with 20 per cent cocain solution. It is often pos- sible to anesthetize the trachea also thus through the tube spatula with a long applicator. After the bronchoscope is passed the cocain solution is apiilied to the tracheal and bronchial mucosje from time to time. In this way a minimum amount of chloroform is needed and the cardiac stimu- lant effect of the cocain is a safeguard of value. After the bronchoscope is passed the chloroform is dropped upon a gauze sponge held intermittently in front of the tube, for but little air is taken in past the tube which is clamped in the glottis by the reflex spasm of the adductors. The preliminary use of atropine to lessen secretion as suggested by Ingals is a good, safe procedure. It has the additional advantage of pro- tecting the circulation from shock. Adrenalin assists in this and also m lessening the mucosal swelling. Passhi^ the broiicliosrope. The author's first work was done by passing the bronchoscope witli the left forefinger as a guide and fulcrum upon which the tube was ti;rncd into and through the glottis by a rocking motion. Tlie pilot was in situ and was removed as soon as the glottis was passed. When Killian devised his ingenious split tubular spatula, the sim- pler method was followed. At present the author uses the split speculum shown in Fig. 7, one battery cord being attached to it and one to the bron- choscope. The method is briefly as follows : The separable speculum is passed in precisely the same way as is the tubular speculum, as described under 48 FASS/XG THR BRONCHOSCOPE. direct laryngoscopy. After the glottic aperture is brought fully into view, the patient, if under local anesthesia, is told to take a deep breath and when the cords separate the well greased bronchoscope without a mandrin, with tubing unattached, is pushed in. .\fter passing the glottis the aspirating tubing is attached if necessary, which it rarely is. The patient does not always take the deep inspiration at command because the glottis is closed by a spasm of the adductors, due to a reflex from the presence of the instrument. He may be making violent efforts to draw in a deep breath, but cannot do so. Slightly withdrawing the in- strument and a quiet reassurance of the patient by the operator usually relaxes the spasm. It is less likely to occur if the laryn.x is well cocainized. If a general anesthetic be used, of course the patient cannot be told to take a deep breath ; but anyway it is needless, as the rythmic respiratory movements of the cords are watched and the bronchoscope inserted just as they are on their inspiratory abductive excursion. The tube mouth should not touch the cords until it is thrust through. The split tulnilar spatula is used in its illuminated form, but the light of the bronchoscope may be used by simply holding it in place within the tubular speculum with the right hand to show when the glottis is exposed to view by the energetic lifting of the split tubular spatula held in the left hand. The operator's eye is held at the bronchoscope, which is then passed by sight. The latter plan is necessary when a double battery is not used. The mandrin is not used, and the battery cord is attached to the bronchoscope from the beginning. In the first described plan one battery cord is used on the separable speculum, and another cord on the bronchoscope. In either method, after the bronchoscope mouth has passed the larynx, the spatula is separated and removed. (See schema, page 53.) Once past the glottis, the entire bronchial tree is easily explored. The left bronchus, which deviates more obtusely from the trachea than the right, is no more difficult to enter with the tube than is the right. The right upper lobe bronchus is perhaps the most difficult. To explore the right bronchus the tulie is moved to the left angle of the moutli, and the head and neck of the patient are moved slightly to the left. The amount of elasticity of the bronchial tree is astonishing. Care must be taken to see that there is always a free passage for air. As shown by Killian if the bronchus examined is occluded by a foreign body, the other bronchus being shut off by the passage of the tube, will leave the patient without air. In passing Killian's tubes the Kirstein headlight should be first care- fully focused and then adjusted before the eye. Then the tube should be warmed, as, if cold, the polish of the interior of the tulic will be dimmed TR.ICllliU-BKUXCIIUSCUry 4SI by the condensation of moisture from the patient's i)reath, wliich will se- riously interfere with the amount of liijht that will reach the nhject at the distal'end of the tube. Much of the li,i;ln that reaches ihe hntmm ni the tube is not tlie direct rays but the rays ret1ecte wall one or more times in the length of the tube. I'or this reason, also, the interior of the tubes must be kept cleaned of secretion and blocd as thonni-hly as pos- sible during the examination. .\11 tubes, of whatever kind, should he lubricateil with vaseline. A jelh- lubricant soluble in water is not satisfactory. In the use of the unil- iuniinated tubes particular care should be taken that none is allowed to get upon the interior walls, as this will diminish the illumination of the object. Particular care is necessary to see that a Mirplus does not get upon the far end of the tube where the wididrawal of the swabs will carry it into the tulie. Another method of jiassing the unillummated bronchoscope is witn the aid of a catheter-like mandrin which is longer than the tube and pro- jects bevond the tube, acting as a pilot. As soon as the catheter passes the glottis, the tube is pushetl on past, also, and then the catheter is (piickly withdrawn. Sufficient air passes through the catheter to prevent inter- ruption of respiration. It may be in some cases advisable to have the tongue drawn forward out of the mouth during the introduction of a tube. The author has not found this necessary except m a few instances, even before the use of the separable spatula. A rocking motion of the tube, throwing the distal end of the tube forward and the proximal end backward, using the end of the left index finger as a fulcrum has always served the author better than drawing out the tongue or pulling it forward with the Kirstein spatula. Much depends upon the operator's training. Those accustomed to intuba- tion will find their index finger the best guide. The separable tube spatula has. however, rendered all other methods difficult by comparison. Thor- ough masterv of direct laryngoscopy renders bronchoscopy easy. An absolute essential in the use of unilluminated tubes is the skillful technical management of the headlamp or handlamp. Many of the utter failures to get results with these tubes is due to faulty management of the Kirstein headlamp. Adjustiiii^ the Kirstein headlamp. I'irst the hood (L l-'ig. i ) should be removed, the mirror (S) and lens cleaned and polished, and then the rheostat run up to the point where full illumination is secured, yet not so high as to burn out the lam]i or materially to shorten its life. This point should be learned bv demonstration if possible. It may be described as the point where the filament seems to thicken and grow white, bcuinning to lose the vellowness of its earlier and weaker stage of illumination. 50 TRACHEO-BRONCHOSCOPY. The next step is to focus the rays. The ho The bifurcation is usually a little to the right of the medium line : about half way between the vertical center line of the sternum and its right border. This varies, of course, though slightly, with the position of the body and with the respiratory movements. Tlie deviation of the right bronchus is usually about ly . and its length unbranched. measured from the bifurcation, is about j.5 cm. The deviation of the left bronchus is about 75°, and its length is about 5 cm. These angles and distances laid off, upon a radiograph, from the bifurca- tion as indicated by the landmarks just referred to, will give the location TRACH EO-BKOX C H I AL TRUE. fi5 of the first branch of the respective main bronclii. These are the land- marks most important radiographically, and for the lateral plane, they are fairly constant and very satisfactory, both for the location of foreign bodies and diseased areas at or above these points. For localization below, they are accurate enough, so far as the lateral plane is concerned, but beginning with the first branch of the bronchi below the bifurcation, the anteropos- terior plane has to be studied, and here the radiograph is not of much aid on account of the distance the rays must pass through the body before reaching the plate, in attempting to take a lateral view of the thorax. However, having localized a foreign body or diseased area in reference to the tracheal bifurcation and the first branch of the main bronchus, we will have accomplished all that is needed in the majority of cases, and in in- stances of involvement of even the deepest bronchi, we will have reduced the area to be explored to very narrow limits. Much remains to be ac- complished in the topographic, radiographic, and endoscopic study of the finer subdivisions of the bronchi and their relation to peripheral lung areas. Dimensions of the traeliea and bronelii. While the lumen of the in- dividual bronchi diminishes as they bifurcate the sum of all the areas shows an increase of total tubular area of cross section. Thus, the sum of the areas of cross section of tiie two main bronchi, right and left, is greater than the area of cross section of the trachea. The same is true of each bronchial branching. TTiis follows the well known dynamic law. The relative increase in surface as the tubes diminish in size increases the friction of the passing air, so that an actual increase in area of cross sec- tion is necessary. This is a fortunate thing for the tracheo-bronchoscop- ist. If the area of cross section were cut in half at every bifurcation he would not get as near the periphery as he now does. The dimensions of the tracheo-bronchial tree may be epitomized ap- proximately thus: Ailult Male. Female. Chilil. Infant. Diameter, Trachea 14x20 mm. 12x16 mm. SxlO 6x7. Length Trachea 12. cm. Ic . cm. 6. cm. 4. cm. Right Bronchus 2.5 " 2.5 " 2. " 1.5 " Left " 5. " 5. " 3. " 2.5 " Upper Teeth to Trachea 15. " 13. 10. 9. Total to Secondary Broiichus..32. 28. 19. 15. These dimensions, especially those given in the last line, are subject to wide variations, and are only approximate. Tliey were taken from the cadaver. The diameters do not take into account the dilatability of the trachea and the amount of yielding of the membranous posterior wall. When the foregoing table is used as a basis for the selection of tubes, several things must be taken into consideration. The full diameter of the trachea is not available for upper tracheo-bronchoscopy, on account of the 66 TRACHEO-BRONChllAL TREE. glottic ajxM'ture which in the atUilt is an cciuilatcral triangle measuring ap- proximately 12x22x22 millimeters, and permitting of the passage of a tube not over ten millimeters in diameter without risk of injury. As to length, a number of additional centimeters will have to be al- lowed. The tube must project above the upper teeth for convenience in working. As to the length of tube required to reach below the first branch of the bronchi, tubes of 45 cm. and even 50 cm. will occasionally be recjuired, though these very long and necessarily slender tubes are usually introduced inside of shorter and wider ones. In many instances, a view is had, and probes and applicators are passed, beyond the tube so that a full length is not always required. The endoscopic appearances of the trachea and bronchi are interest- ing and their study is easily accomplished. The appearance of the inte- rior of the trachea is familiar to all who have used the laryngeal mirror. The interior of the bronchi in the living was never studied until the advent of the bronchoscope. As seen in the bronchoscope the trachea is a tube slightly flattened on the posterior wall. It assumes in some instances a greater or lesser tendency to an elliptical outline, the longer axis being variously placed. This is noted more particularly in twV) locations. The upper flattening is in the cervical portion and is due to pressure of the thyroid gland. The lower one is intra-thoracic, just above the bifurcation, and is due to the pressure of the aorta. This flattening is rythmically increased with each pulsation. In children a flattening is occasionally noticed due to pressure of the thyroid gland. In mentioning these flattenings reference is had only to conditions strictly within the limits of health. All these changes of outline may be enormously exaggerated, even to entire obliteration of the tracheal lumen, in diseased states. The entire trachea is often seen to deviate slightly, usually toward the left, and occasionally it is seen to deviate first in one direction, then in another, making a slight tendency to an S curve. The mucosa of the trachea is moist and glistening, whitish in circular ridges corresponding to the cartilaginous rings, the intervening grooves being reddish. At the bottom of the trachea a white shining ridge is seen to divide the trachea antero-posteriorly into two unequal parts. The ridge shades ofif anteriorlv and posteriorly into two reddish triangles. On the left of the ridge is the slanting orifice of the left main bronchus, and on the right, its larger fellow. Passing the tube down the right bronchus, a view is presented that differs considerably in different instances. The view shown in Figure 11, TRACHEO-BROXCHIAL TREE. (57 Plate II, is from a water color drawing of the right hrcjiicluis of a man 25 years of age. In Figure 47 the same view is shown without color. At the right (SL) is seen the orifice of the fi.rst branch, the upper lobe bronchus. Farther down anteriorly is seen tlie orifice of the middle lobe bronchus (M). At the left (1) we look into the depth of the inferior lobe bronchus in which the orifices of ventral and dorsal branches arc seen. In Figure 46 is shown a bronchoscopic view of the left bronchus of this same man (see also colored Plate II, Fig. 10). At S is seen the opening of the superior lobe bronchus while th.e entire right of the view shows the inferior lobe bronchus, (really the continuation of the main bronchus) with the 0[)enings of the dorsal and ventral Ijranchcs in more or less perspective. It will be noted that the dorsal and ventral branches are not given ofl:' opposite each other. Tlie reference letters are duplicated in the dlustration of the traclieo- FiG. 40. Fig. 47. Bronchoscopic views. Left bronchus. Right bronchus. S. Superior lolic bruiHii.w. S L, Superior lobe bronchus. I, Inferior lobe bronchus. .M. iliddle lobe broiu'hu>-. bronchial tree, Figure 45, and it will be found useful to study these to- gether. Not that they are to be taken as accurate representations of con- stant anatomical types, but, rather, as a suggestion as to how the tracheo- bronchial tree is to be studied endoscopically. The illustrations are semi- diagrammatic. The mucosa of the bronchi is siniilar to that of the trachea, showing, however, difil'erenccs meriting the closest scrutiny. The movements of the trachea and bronchi as observed endoscopically in health and disease are worthy of study, of -which thcv have as yet re- ceived but little. The normal movements may be classified as respiratory, pulsatory, and deglutitory. The two former being rythmic the latter be- ing noticed occasionally, and only in lower tracheoscopy. Various spas- modic and transmitted movements, the true nature of which has not yet been demonstrated, have been noted. CHAPTER VII. Tracheo-Bronchoscopy in Diseases of the Trachea and Bronchi. The brilliant work in the removal of foreign bodies has led to the im- pression that tracheo-bronchoscopy is useful for this only. The near fu- ture, however, will see the bronchoscope, and even more the tracheoscope and tubular speculum, in frequent use for the diagnosis and treatment of diseased conditions. The diseases of the trachea and bronchi in which tracheo-broncho- scopy is useful may be divided into non-stenotic and stenotic. All cases of stenosis of the trachea or bronchi justify tracheoscopy, upper or lower, as may be indicated. Of the non-stenotic tracheal diseases it is chiefly those in which no satisfactory view is obtainable by indirect or direct lar- yngoscopy that will demand tracheoscopy. Of non-stenotic bronchial dis- eases, many that cannot be said at the present day to demand broncho- scopy, certainly should be investigated from a scientific point of view, as thus our knowledge of n:aii}- bronchial and pulmonic conditions will be in- creased. Nou-stcnolic morbid conditions of the trachea and bronchi may be tabulated the same as the stenotic diseases, the difference being chiefly of degree. In addition, however, there are a number of diseases rarely associated with stenosis. Acu.te and chronic inflammatory conditions of a mild type usually called "catarrhal," objectionable as this word may be, will occasionally demand tracheoscopy when they cannot be examined by in- direct or direct laryngoscopy. Many of the chronic inflammatory condi- tions will require tracheo-bronchoscopy, not only for diagnosis but for treatment of the diseased conditions revealed. Many a case labelled ner- vous cough, and allowed to annoy the patient and relatives for months will be found, when tracheo-bronchoscopized, not only to be due to visible lesions, but to lesions that can be cured. TRACHEO-BRONCHOSCOPY . 69 In a case of this kind referred lo mc by Dr. L. W. Swopc, an annoy- ing cough of several months' duration, which had been disturbing rest and producing emaciation, was promptly cured by six direct swabbing appli- cations of argentic nitrate to a non-specific ulcer discovered, at the bifur- cation of the trachea, by tracheoscopy. Ulcerations more deeply seated, as in -inother case of the author's at the bifurcation of a bronchu';, may be discovered and treated. Qironic tracheal inflammation, that does not yield to treatment based upon indirect laryngoscopy, justifies direct laryngoscopy or tracheoscopy for diagnosis and treatment. The same may be said of ozena, if necessary for diagnosis, but the results of treatment are so far too discouraging to render it advisable. Pus foci near the periphery of the lung may be endoscopically evac- uated or may be localized for the general surgeon to attack externally. Necessarily the cases of this kind of tracheoscopic possibilities will be those in which communications have been established with the bronchi of not too small lumen. Knowing the anatomy and the normal endoscopic appearances, the bronchoscopist starts his tube downward from the trach- eal bifurcation, noting the orifices of the lateral branches as they are passed until a bronchus is reached in which disease products are found, or the walls of which give ocular evidence of disease, as inflammation, perforation, granulation. Specimens may be taken with a mop or aspi- rated into the accessory drainage tube. As orientation is not easy, a radiograph ma}' be taken after blowing in bismuth oxide through a dry extra drainage tube. Abscesses of the lung due to the presence of a for- eign body may be thus localized ; and if the foreign body cannot be re- moved endoscopically, a probe passed through the bronchoscope into the pus focus can be felt through the lung and pleura after the thoracic wall is opened. Stenoses of the tracliea may be classified as to their pathologic mech- anism into peri-tracheal, muro-tracheal and endo-tracheal conditions. Bronchial stenoses may be likewise classified. In considering peri-tracheal conditions causing stenosis we nnist re- member that the trachea, though not soft as compared with the esophagus, is not a rigid tube. It is very readily compressible, and is subject to the encroachment of cervical and intra-thoracic tumors. Peri-tracheal con- ditions producing stenosis include glandular hypertrophies, glandular (lymphatic) infiltrations, aneurysm, benign and malignant tumors of ad- jacent tissues. The great frequency of stenosis from these peri-tracheal and peri- bronchial conditions was not known until the development of- tracheo- bronchoscopy, as in many instances they do not show at autopsy. 70 1 RACHEAL STENOSES. Of glandular livpcrtropliics the most frequent is the thyroid. Struma intrudes upon the tracheal lumen much more frequently than was sus- pected until tracheoscopy was extensively practiced. The outline of the cross section of the tracheal lumen may be compressed from before back- ward and to one side as in Figure 2, Plate I, drawn from a case of goitre in a man 36 years of age. Or it may be compressed in addition from behind forward by the retro-tracheal portion of the goitre producing a narrow oval slit, the so-called "scabbard" trachea. The long axis of the ellipse is more apt to be at an angle than exactly in the transverse plane owing to the relative frequency of asymmetric Aruma. For many years it has been a disputed question as to whether the thymus gland can compress the trachea. It has been the author's privi- lege to demonstrate tracheoscopicallv the error of Friedleben's dictum, "Es gicbt kein asthma thyuiiciun:' This case, already reported, is here briefly abstracted : Case XXI, Earl L., aged 4, was admitted for dyspnoea and stridi^rous breathing, increasing since the sudden onset of a croupy attack six weeks before. Immediate tracheotomy by the author failed to relieve the dysp- noea, but the passage of a tracheoscope relieved it completely. Tlie walls of the trachea were collapsed from before backward (Fig. 5, Plate I) and they opened up ahead of the tracheoscope like the cervical esophagus, and like those of the esophagus they tended to close on expiration. One of the author's long tracheal canulae was inserted which relieved the dysp- noea, and later held the trachea open while the little finger was passed be- hind the sternum into the anterior mediastinum, and while the thymus gland was thus brought up and removed. The d\spnoea never recurred and a complete cure resulted, without ill eiTect from the absence of the gland. (Fig. 48.) A radiograph by Dr. Russell H. Boggs shows th; hypertrophied gland before operation. (Fig. 49.) This case demonstrates the diagnostic value of tracheoscopy in com- pression tracheo-stenoses. In the absence of his long tracheal canulx the author has more than once used a tracheoscope as a temporary canula until one of the latter of proper length could be procured. Infiltrated lymph nodes frequently produce stenosis of the trachea and bronchi. Fig. 15, Plate II, shows compression stenosis of the right bronchus thus produced, in a woman of 26 years. Benign and malignant tumors of the peri-tracheal tissues produce compression stenoses. Such a case is illustrated in Fig. 9, Plate I, wdiich is drawn from the case of a man, aged 60, in whom an epithelioma of the thoracic esophagus produced a compression stenosis of the trachea. Later the tracheal wall became secondarily involved by extension of the infiltra- THYMIC TRACHEOSTENOSIS. 71 Fig. 4S. — From photograpli of patieut 4 months thymic Iracheo-stei.osis diagnosticaterl tracheoscopically after th.vmi'ctom.v. Case of TRACHEAL STENOSES. Fli;. V.) — Tliymic traflieo-stenosis. ItacHograpb sUovviiig gland before operatiou. TRACHEAL STENOSES. 73 tion. AFediastinal tumors are frequently the cause of tracheal compres- sion. Aneurysm is a not infre(|uent invader of the trachea and bronchi, as shown in Fig. 3. Plate I, drawn from the case of a man aged 50, a physi- cian. The excursion of each pulsation is shown by the dotted line. This pulsatory excursion inward of one portion of the tracheal wall must not be confused with the transmitted cardiac or aortic impulse in which the entire trachea is pushed or tugged aside. A radiograph of this case is reprotricturc. Very often this will be of almost a pin-hole size seen in tlie ll:it wall against which the tube moutl! is gently pressed. Often prolonged exploration of a diverticulum or a number of diverticula will he necessary before the strictural opening is discoveretl. When found, the smallest Hmit bougie is inserted. If it pass readil}', the next size is inserted, and so on up until a size is reached whose distal olive passes readily, but the second olive en- gages. Tliis is pushed through and the next larger size is used. At the next treatment, three or four days later, these same sizes are used again, followed bv one size larger. This is continued until a sufficientl)' large lumen is secured to permit the patient to swallow solids normally. The ordinar\- flexible silk-and-wax bougie is then gently tried with- out the esophagoscope, the patient being instructed to make continual-swal- lowing efforts wdiile the bougie is being passed. If the flexible bougie pass readily, the patient is taught to pass it himself, and instructed to pass it regularlv once a week or oftener, if any signs of strictural closure super- vene. After a time, once a month will be enough. This may be called a symptomatic cure and is brilliant compared to gastrostomy, either with or without retrograde chlatation. Of the other methods, dilatation with a laminaria tent placed with the aid of the esophagoscope, deserves mention. It is carried on the end of a stylet fitted to the tube forceps (Fig. 22). The disadvantage to tent dila- tations is that the tent expands more below the stricture than at it. This lower expansion in extraction has tc be pulled through th.e stricture. This is not often difficult to do, but may be attended with slight risk, though no cases of untoward results have come to the author's knowledge. The axial tugging on the esophagus, rather than the stretching of the circum- ference constitutes the danger ; for as demonstrated sphygmomanometri- cally by Boyce on some of the author's cases of laryngectomy, tugging on the esophagus produces a great fall in blood pressure. Instrumental dilatation with steel expanding forceps is a feasible pro- cedure and is advisable in a few instances. There is always some risk of rupture of the esophageal wall, which is a very serious complication. There are many other plans of treatment, instrumental, electrolvtic, etc., but that given is the most practical. Medicinal treatment is of no use so far as cure is concerned, but it may be well to know that cocain. adrenalin and morphin have a decided effect in temporarily opening a stricture sufficiently to permit liquids to pass. This is of use at times in tiding over a few davs, when the patient is not seen until he is in a serious state of inanition. Under these circum- stances it is also well to know that ice cream will go down when nothing else will. The action of the cold probably is to contract the chronically 110 MALIGNANT DISEASE OF THE ESOPHAGUS. inflamed mucosa, so as temporarily to increase the available lumen. Of course most of the ice cream is regurgitated, but enough leaks through to prevent starvation. Malignant Disease of the Esophagus. As in malignant disease elsewhere in the body, the crime of the day is in the failure to recognize malignancy and pre-malignant conditions early. It is not until emaciation, cachexia, regurgitation and absolute ina- bility to swallow solids supervene that the profession, even the laryngolog- ical member of the profession, thinks of serious disease of the esophagus. All earlier stages are dismissed thoughtlessly with the label "globus hys- tericus." Illustrative of this the following case may be cited : Miss L., aged 41, was under the author's care for chronic maxillary sinuitis. She mentioned incidentally that she felt a lump in her throat at times upon swallowing. When asked if she felt the lump rise in her throat when she was not attempting to swallow, she answered that at times she did. There had been no difficulty in getting even solid food down, and there was no regurgi- tation. She was undoubtly a neurasthenic, yet the author has made it a rule to consider that a neurasthenic may have a lesion as well as a person without neuropathy, and that a person with abnormal esophageal sensations should be examined as well as one with abnormal laryngeal sensations. In this instance, it was two months before the attending physician grudingly gave his consent to an esophageal examination. Under ether, preliminary to a secondary sinus operation, the esophagoscope was passed and an epithelioma (Fig. 8, Plate III.) discovered. The foregoing case dlustrates : 1. The latency of esophageal symptoms. 2. TTie necessity for the examination of the esophagus in all cases where any chronic throat symptoms, other than laryngeal, are complained 3. The fallacy of labelling (it would not be accurate to say diagnos- ticating) a case of "globus hystericus," because the patient complains of "a lump rising in the throat," whether she be a neurasthenic or a hysteric subject or not. Malignant diseases of the esophagus for esophagoscopic purposes may be divided into endo-esophageal, muro-esophageal and peri-esopha- geal diseases. Naturally this only applies to the early stages. Late in the disease all three forms are usually combined. Peri-esophageal disease in its earlier stages will present a hard resist- ing sensation to the end of the esophagoscope, though the overlying muco- sa is normal. This is well shown in Fig. 7, Plate III, where the mass is to the left, the lumen to the right. This deviation of the lumen must be dis- tinguished from the simple neglect of making the tube follow the direction MALIGNANT DISEASE OF THE ESOPHAGUS. 1 1 1 of the axis of the normal hinien. The figure is drawn from a case of epithelioma in a man 6o years of age, referred lo me by Dr. Sanes. Tlie esophagoscope could not be introduced past the hard mass, though the mucosa was normal. Later the wall and still later the mucosa, became involved. The esophagoscopic appearances of nuiroand endo-esophageal ma- lignancy varies in different cases and in different stages. In the early stage Von Acker regards distinctive, slight narrowing of the lumen with islands of infiltration raising the mucosa in spots, the mucosa being red- dish with purplish hemorrhagic dots, and with here and there enlarged vessels visible. This is an early condition prior to ulceration. Gottstein, whose experience is large, describes five forms of esoph- agoscopic appearances in esophageal cancer. 1. Segmentary mural infiltration in thickened whitish patches alter- nating with bright red. 2. Annular form, seen as a more or less extended ring of infiltration which narrows the lumen below a fungating ulceration occupying m.ore or less of the ring. Above this ulcerated area there is more or less dilatation dependent upon the duration of the narrowing. The mucosa of this dilated area is more or less altered. 3. Carcinomatous infiltration not only annular but funnel-shaped. 4. Bleeding cauliflower fungating masses. 5. Papillomatous vegetations. The most common in form is the second. Stoerk urges the diagnostic importance of the absence of the respira- tory enlargement and the diminution of the esophageal lumen, due to infil- tration of the esophageal walls. He also attaches weight to flat infiltra- tion, bleeding after wiping, and superficial ulceration of the tumor. It must not be forgotten that all of these appearances may be simu- lated by syphilis, but the therapeutic test will soon distinguish. The taking of a specimen is in all cases advisable, and is quite harm- less. If bleeding follow, which is rare, it can be stopped by swallowing ice cream, iced water, or pieces of ice. Epithelioma and endothelioma may be distinguished microscopically with some degree of certainty, if an adequate specimen be removed. But, obviously, the pathologist can only report on the specimen submitted, so that a good, ample specimen must be obtained, preferably one at the edge of the neoplasm and including both normal and neoplastic tissue. In cases of deep-seated growth covered with normal mucosa, it is useless to take a specimen unless the forceps be plunged deeply into the mass, which is seldom justifiable. In fibro-sar- comata, of which the author has seen one case, the microscopic appear- ances are characteristic, as they are also in sarcomata of other than the 112 BEXIGN NEOPLASMS OF THE ESOPHAGUS. small round-celled variety. The latter form is not with certainty dis- tino-uishable from tuberculoma, syphiloma, and inflammatory round-celled infiltration ; at least such has been the author's experience from small in- adequate specimens submitted to various pathologists. If the entire mass or a portion extending from the surface of the growth clear down into healthv tissue be obtained, the pathologist would have a fair opportunity and could give a dependable opinion in all cases. Tlie treatment of malignant disease of the upper portion of the esoph- agus when associated with similar disease in the larynx may be extirpated by resection of the esophagus at the laryngectomy. For extensive opera- tive work upon the upper end of the esophagus, Mosher's ingenious spec- ulum (Fig. 5) is well adapted. If the patient be not tracheotomized it is necessary to watch the breathing carefully while using this, as the broad flat surface is apt to close the laryngeal orifice. The author has had a large oval opening made in the spatular part of iMosher's instrument which obviates this to a great extent. It is better in most cases to do a trache- otomy as the chloroform may be administered through the tracheal canula bv means of a simple piece of rubber tubing one end of which is fitted into the tracheal canula, while the other end has tied over its extremity a tuft of gauze upon which the chloroform is poured. Used with a tracheotomy, the Mosher instrument has the advantage of closing the laryngeal orifice so that tamponade of the larynx is unnecessary, or if tamponade be needed the instrument serves to hold the previously placed tampon in place. In deeper portions of the esophagus palliative treatment will greatly prolong life and relieve pain. When stenosis threatens to interfere with nutrition the esophagoscope is introduced and the narrowed lumen dilated, as described in reference to cicatricial stricture. Tlie ordinary flexible bougie should never be used except after the esophagoscope has deter- mined the absence of ulceration or weakening of the esophageal wall. Benign Neopt^asms of the Esophagus. Benign neoplasms, when large enough, produce esophageal stenosis. In many instances, however, they will be discovered quite accidentally. In this connection, however, it must be remembered that, at the present dav, slight difficulty or inconvenience in swallowing is either absolutely ignored or labelled "neurasthenia" or "globus hystericus," and dismissed. Such a thing as examining the case with an esophagoscope does not seem to occur to the clinician's mind. When the neglected subject of esopha- geal disease receives its merited study, benign tumors will be found to be less infrequent than is at present supposed. Edematous polypus has been observed but is rare. The most fre- quent benign tumors are. papillomata, fibromata, myomata, fibromyomata, mixomata, angiomata, lipomata, adenomata and cystomata. BHXIGX MiOrL.ISMS OJ- THE IlSUI'U .IGUS. 11.'? The base of a benign ,u;n>\vth is never indurated : though we must be on our guard against diagnostic error in case of its occurring at the site of a scar. The naked eve diagnosis of benign tumors is only possible when they are observed to have long, distinct pedunculi. Malignant ncoplasmata rarely, if ever, occur ni this form. All sessile growths, whether ulcerated, fungating or smooth, can only be diagnosticated with certainty by the aid of the microscope. The removal of a specimen is always justifiable. No hemorrhage need be feared, if one condition be excluded, namely, vari- cosities of the esophageal vessels. Even in such a case it is doubtful if any hemorrhage will occur that will not yield to the eating of ice cream, or the swallowing of pieces of ice. Treatment. All benign tumors of the esophagus demand removal. Tlie possibility of their undergoing malignant degeneration is disputed, but, while it is true that cells never change their type, the benign neoplastic tissue is more liable than normal tissue to become the site of a malignant neoplasm. For removal, strong forceps are necessary, especially in case of pe- dunculated tumors. Necessarily the pedunculi are tough and strongly attached, else the growth would be detached and swept downward by the swallowed food. It is necessary as a rule to bite out the mucosa where the peduncle is attached, not only because it is safer than the severe trac- tion necessary to tear away the growth, but to prevent repullulation. This is illustrated in the following case : Mr. P., aged 36 years, was referred to the aiitlmr by Dr. Heard for vague and indefinite throat symptoms, which would certainly not have aroused any suspicion of esophageal disease in a mind not particularly bent toward the subject. He said his throat "bothered" him, he had some "throat trouble" and like indefinite expressions of his unlocated sensations. There was some cough, also occasional hoarseness. Examination with the laryngoscope revealed a chronic laryngitis, nothing more. Examination of the upper end of the esopha- gus with the laryngeal speculum revealed whitish granular tumor attached by a pedicle three centimeters in length. (Eig. 12, Plate III.) The pedicle was at- tached about two centimeters below the level of the inlerarytenoid space. Upon a subsequent e-xamination with the laryngeal mirror the growth was seen lying in the inlerarytenoid space (Fig. 9, Plate III.). The growth was certainly not there at the first examination with the laryngeal mirror. The mystery was ex- plained, however, when the patient was told to swallow, and upon re-examina- tion the tumor was nowhere to be seen. The long pedicle permitted the tumor to rise above the introitus like a floating buoy above its anchorage, but in swallowing the growth was carried below the inferior constrictor. With the assistance of Dr. Heard, the neoplasm was removed under local anesthesia by direct inspection through the tubular speculum (Fig. 6). The peduncle was found of such a tough fibrous nature that the esophageal wall was pulled into the mouth of the speculum, without tearing away. The cup-shaped forceps 114 SPASTIC STENOSES OF THE ESOPHAGUS. (Fig. 24) were then used to bite out the esophageal wall to which the peduncle was attached. The wound healed promptly and si.x months later there was no sign of recurrence. The growth was examined by Dr. Jonathan Wright, who pronounced it fibroma papillare. This case is interesting as showing: 1. The absence of symptoms associated with small esophageal neo- plasms. 2. The likelihood of overlooking such conditions. 3. The necessity of examination of the esophagus in all doubtful throat cases. 4. The ease with which the upper end of tlie esophagus can be ex- amined, and the ease of removal of neoplasms therefroni, with the aid of the tubular speculum. 5. Tlie advisability of excision of benign growths with the cupped forceps, as compared to evulsion with serrated forceps. Many benign growths have a strong tendency to recur. They do not infiltrate, hence are not malignant, but they repullulate in a most stubborn manner if any portion is left. Spastic Stenoses of the Esophagus. Cardiospasm, as its name implies, is applied to a condition of spas- modic closure of the cardiac orifice of the stomach. It is applied, how- ever, to spasmodic closure of the esophageal lumen without limitation strictly to the cardia. The cardia is not a genuine sphincter, though Hyrtl has demonstrated circular fibres. The prevention of regurgitation is prob- ably as mucli a ki'.iking of the esophagus due to expansion and upward movement of the fundus ventriculi as to any sphincter-like action at the cardiac orifice. There is, however, a distinct sphincter-like action at the hiatus esophageus. Wherever future study may demonstrate the seat of the spasm to be, there can be no doubt of its occurrence. Many observers have seen it. In all three of the author's cases it occurred in the abdom- inal esophagus between the cardia (as indicated by the mucosa) and the hiatus. In two of these cases it was associated with peptic ulcer of the abdominal esophagus. It disappeared completely while the patient was under deep general anesthesia. It was associated with slight dilatation of the superjacent esophagus. A number of competent observers have noted this dilatation of a very marked degree. Phrenospasm is a name given by the author to a closure of the esoph- agus at the hiatus esophageus by a tonic spasm of the neighboring portion of the diaphragm. It is frequently seen in passing the long esophagoscope or gastroscope without anesthesia or in withdrawal of the instrument after the tube mouth has retreated from the hiatal portion of the esophagus. Frequently in the absence of anesthesia, the instrument is clamped so COMPRESSION STENOSES OP THE ESOPHAGUS. 115 tightly in this plircnospasni that the niovoments of the tube are hindered. It disappears completely during the relaxation of deep general anesthesia. This complete disappearance of the obstruction, along with a normal yield- ing wall and a normal mucosa establishes the diagnosis absolutely. It is almost invariably associated with dilatation of the portion of the eophagus immediately above it, just as organic stricture is. Esophagospasni or esophagismus is usually the condition found m globus hystericus. It is associated with great difficulty in introducing an esophagoscope under local anesthesia, but it disappears promptly under deep anesthesia, when the esophagoscope may be passed freely up and down the esophagus, revealing a wall of normal resiliency, which wall shows the normal respiratory excursion, and which is covered with normal mucosa. Occasionally esophagisnuis will be found to be secondary to a lesion, the most frequent lesion being a simple ulcer. The treatment of spastic conditions of the esophagus may be pallia- tive or curative. Palliative treatment consists in the use of iced liquid food in some instances, of hot liquids in others. Drugs as morphin and cocain have an effect, but their use should be avoided. Curative treat- ment consists in the cure of ulcers if present, in the application of gal- vanism with the olive-pointed electrode, and in bouginage. After the esophagoscope has demonstrated the normality of the esophageal wall, the daily passage of the flexible esophageal bougie by the patient will establisii a cure after extreme tolerance to the bougie is developed. Retrograde in- strumental dilatation is used in extreme cases, but the esophagoscopic di- latation is the most useful in abolishing the hypersensibility of the esoph- agus, which is the chief factor in many cases. Compression Stenoses of the Esophagus. Compression stenoses of the esophagus are produced by many differ- ent conditions. Hypertrophic, inflammatory, neoplastic and exudative diseases of adjacent tissues may compress the esophagus. The most fre- quent conditions are: struma, glandular infiltrations, mediastinal or cer- vical tumors, aneurysms, pleural and pericardial effusions, abscesses, spinal deformities, etcetera. The differential diagnosis of these conditions depends less upon end- oscopic examination than upon general clinical diagnostic methods. Tlie location of the stenosis as measured esophagoscopically is often an aid. In aneurysm the pulsations are diagnostic, if the observer is familiar with the normal pulsatory movements as observed in the esophagoscope. The radiograph is a very important aid in diagnosticating aneurysm and some forms of mediastinal tumors. (Figs. 50 and 62.) In aneurysm the pul- sations may be seen fluoroscopically. Fill. 62. — Radiogram showing location of a malignant mciliastmal tumor produc- ing ctanpression stenosis of the esophagus. CHAPTER XV. Non-5tenotic Diseases of the Esophagus. Diverticula. A divcrticulniii is a circumscribed ectasi?. of the esophageal wall, in centra-distinction to a dilatation which is a diffuse ectasia. Though a di- verticulum of the esophagus is not in itself a stenotic disease, it is usually associated with a subjacent stenosis, which is the chief factor in its pro- duction, lliis form is called a pressure diverticulum, because of the probable etiologic influence of the pressure of the esophageal contents, which the musculature is endeavoring to propel. The other form is called a traction diverticulum, being due tc traction, as by an adhesion, externally on a circumscribed portion of the esophageal wall. The esophagoscopic picture is not as clear as might be at first sup- posed, though the diagnosis can be made in every case bv careful explora- tion. The possibility of the presence of a diverticulum must be borne in mind in every case of esophagoscop}-. ^^'hen the esophagoscope enters the diverticulum the orifice of the sub-diverticular esophagus is usually not noticed. The tube mouth comes against a flat surface which is usually mistaken for a strictural or neoplastic stenosis. The tube is withdrawn and yet no orifice is seen. Often it cannot be found until regurgitation forces some fluid through, or forms one or more bubbles. The orifice is usually very small, often slit like, and hidden by a fold or band. To favor regurgitation, the patient, if under general anesthesia, should be allowed to come out partially. The bottom of the diverticulum is usually chronically inflamed as shown in Fig. 5, Plate III, drawn from one of the author's ca.ses. This chronic inflammation is probably due to the pres- ence of food, which is not well tolerated by the esophagus. The normal esophagus endeavors to rid itself of everything, even its own secretions, by upward or downward expulsion. Frequently the diverticulum will be found full of secretions, but, with the aspirator attached to the esophago- scope, (Figs. 17 and 18,) the latter is slowlv inserted and the secretions 118 DILATATION OF THE ESOPHAGUS. removed ahead of the tuhe in a manner that eliminates all trouble from this source during the examination. Large masses of food, sometimes present, may be removed with the forceps. The treatment of diverticula is mainly surgical. Dilatation of the sub-diverticular stricture will produce a symptomatic cure and occasion- ally some recession of the size of the diverticulum may thus be brought about, if the strictured passage be kept open. If so located that external surgery is of aid, a radical cure may be brought about. Such cases have been reported by Depage, Kocher, Bilroth, Goris, and others. DlL.^TATlOX OF THE EsOPHAGUS. Dilatation is a diffuse ectasia of the esophageal wall, in coiitra-dis- tinction to a diverticulum which is a circumscribed ectasia. The most common form is the spindle shaped esophagus. It is very rare in tiie upper portion of the esophagus. It occurs in three classes of cases : 1. Those in vvhich there is below the dilatation an anatomic stricture which is evidently its cause. 2. Those in which there is a spasmodic stricture, usually a phreno- spasm or cardiospasm below the dilatation. 3. Those in which there is no stricture anatomic or spastic demon- strable, and which are supposed to be due to atony of the esophageal wall. There is every likelihood that there has existed at some previous time a cardiospasm or a phrenospasm. Various clinical and chemical methods of differential diagnosis be- tween diffuse dilatation and diverticulum have been advocated from time to time, but none of them compare in accuracy with the simple procedure of esopliagoscopy, by which we put a tube down and actually see the con- ditions present. The esophagoscopic picture in dilatation is unmistakable. In the normal esophagus, the walls are visible at all times ; the lumen enlarging upon inspiration, but never to such an extent that the walls are not visible. In dilatation, on the contrary, during inspiration the entire wall disappears and the tube end is seen to be in a large cavity, the walls of which are ballooned out. The upper wall, if the patient be in dorsal decubitus, may sag downward, and it will be noticed that to bring the lower (posterior) wall into view the tube mouth must be lowered quite a distance. Later- ally the enlargement of the lumen is equally apparent upon a lateral move- ment of the tube mouth. Of course, this description applies to extreme degrees of dilatation. All sizes and stages of dilatations are met with and the lesser degrees may raise the question of the border line between normalitv and disease. DILATATION OF THE P.SOPHAGUS. 119 The dilatation is not always concentric and it is not always possible to determine whether it is concentric or not. The possible extent of lat- eral drag in all directions is some criterion, but this varies within the limits of health, and considerable experience in esophagoscopy is neces- sary to determine the degree of eccentricity of the dilatation, and, indeed, the presence of a dilatation, if the dilatation be of very slight degree. Dilatations, if of any size, usually contain food particles, and also more secretion than the normal esophagus, due to the chronic turgescence and inflammation of the mucosa. TTie accumulation is due rather to the obstruction below, and to the motor insufficienc}- than to the mere dilata- tion per se. The mucosa often shows dilated capillaries and occasionally erosions. In cases associated with cicatricial stenosis, cicatrices may be seen. In pushing the tube on downward the presence of the subjacent stenosis and its character, whether anatomic, cardiospastic, or phrenos- pastic will be determined as before described when speaking of stenotic diseases. A tumor more frequently malignant than benign may exist in the dilatation. Ulceration, benign or malignant, occurs. In cardiospastic and phrenospastic dilatations, the mucosa is very much reddened, especially in the upper two-thirds of the dilatation. In the lower third, it is usually paler and the dilated branching capillaries are particularly noticeable at the site of the spastic stricture. Below this the mucosa is sometimes noticed to fold in over the end of the tube in transverse folds. The differential diagnosis between spasmogenic dilatations and those resulting from anatomic stricture is easily made by the determination of the presence or absence of an anatomic stenosis. TTie differential diagnosis between spasmogenic and atonic dilatations, if, indeed the latter kind ever exists alone, is difficult. As previously stated, tlie author's belief is that the so-called atonic dilatation is a result of pre-ex- istant spasmogenic conditions. The differential diagnosis between dilata- tion and a deeply situated diverticulum, impossible by other methods, is easily made esophagoscopically. If a diverticulum exists, no hiatal slit or cardia will be found, instead, the tube mouth will stop against a lightly stretched wall, the bottom of the diverticulum. The orifice of the sub- diverticular esophagus can be found by careful search as the esophago- scope is very slowly withdrawn. The treatment of dilatations is based upon eradication of the cause. The subjacent stenosis, anatomic or spastic must be dealt with. If ana- tomic it is treated as previously outlined, by dilatation, forcible or prefer- ably gradual. The wearing of a short tube or sound for an hour or more is beneficial, but the size must be exactly determined so as to cause some dilatation and yet not too much. The size should be gradually increased, 120 INFLAMMATIOX .IXD ULCERATION. and a strong heavy braided silk cord must be attached for removal. Electrol\tic dilatation of the stricture might be tried. The inflammation and ulceration of the mucosa can be treated by topical applications, if necessary, after the relief of the dilatogenic stenosis. Often it will not be necessary. Inflammation and Ulceration of thic Esophagus. Acute csophagitis arising from any cause save traumatism is a posi- tive contra-indication to esophagoscopy. Where due to traumatism, esophagoscopv is also contraindicated save where the traumatic agent, as a foreign body, is still in the esophagus. In this case it should be re- moved at once. The esophagoscopic appearances are those of an acute mucosal in- flammation elsewhere. Intense congestion of the mucosal capillaries pro- duces as intense reddening, which may be diffuse or circumscribed ac- cording to origin. If the inflammation is more intense in some point than others, a flecked or patchy appearance may be observed. After the in- cipient stage is passed, if serous effusion takes place, the mucosa assumes the edematous semitranslucent appearance often seen in the larynx. Vessels are not, as a rule, visible in acute inflammation. Acute inflammation is easily diagnosticated, but care must be taken that we do not overlook associated lesions. For instance, a nniral esopha- geal carcinoma may be intruding the overlying mucosa into the lumen, wherewith the irritation thus resulting, the mucosa may give the ap- pearance of acute inflammation. Chronic csopliagitis may follow acute csophagitis, or, more fre- quentlv. it mav be the result of long-continued irritation of food particles, mucus, ])us, etcetera, which are entrapped in the esophagus by spastic or anatomic stenoses, dilatations or diverticula, which prevent the esophagus from immediately emptying itself, which it always does promptly under normal conditions. Uncomplicated simple catarrhal inflammation of the esophagus exists, commonly in alcoholics, due to general engorgement and vaso- motor relaxation from the systemic action of the alcohol, and also from the local irritant eft'ect of the insufficiently diluted alcohol upon the esophageal mucosa. Catarrhal inflammations also result from other causes local and systemic, the latter usually diathetic. The esophagoscopic appearances are usually a dirty gray, or grayish white, or pale red, sometimes mottled, mucosa streaked with vessels, and covered with a tenacious mucus which is sponged away with difficulty. (Fig. 5, Plate III.) ULCliRATlOX or rill-. JiSUI'JLlGUS. 1-il Ulceration is often seen. I'lcers may be divided into two general classes : Those above and those lielow the hiatus. 'I be npjier class may be due to the same causes as tlie innammation. abrasions and the like, or they may be due to the intensity of the inflammation itself, resulting in a localized tissue necrosis. They may be due to a local thrombosis of em- bolic or other origin. Those occurring in tyjihoid fever are usually of thrombotic pathology. Epithelial erosions frequently occur in profound toxemic states in the course of the general infections. Deep ulcerations occur in syphilis more often than is realized, as unless the resultant cicatrix is sufficient to interfere seriously with de- glutition the lesion is overlooked, as it is usually painless. Deep ulcera- tive lesions occur in tuberculosis, and is very frequently overlooked. As much as four-fifths of the esophagus has been known to be involved without an esophageal disease having been suspected. The author has seen a great many cases where the dysphagia and odynphagia present were attributed to the concomitant laryngeal tubercular lesion. Tuber- culosis of the esophagus, like that of the larynx, is usually secondary to a pulmnnarv lesion, the infection being conveyed by the sputum: or it mav occur by continuative extension from a tubercular bronchial gland or vertebra. It may occur by contiguous extension, as for instance on the posterior wall from contact of the tubercular larynx. (Fig. 6, Plate III.) Peptic ulcer. Ulcers occurring below the hiatus esophageus are usual- ly classed as peptic ulcers and often bear a strong resemblance to peptic ulcer of the stomach. They are often attributed to functional insuf- ficiency of the cardia. but the author's opinion elsewhere stated is that the functional closure of the upper end of the stomach is due to a kinking of the esophagus at the hiatus, due to pressttre of the gastric fundus and the peri-hiatal structures. This permits the stomachal contents frequently to invade the lower end of the esophagus. Whatever may be the ]:)athology of peptic ulceration of the esophagus, it has a pathology essentially dif- ferent from that of other mucosal ulcerations. In whatever they may consist these differences are participated in to some extent by duodenal and lower esphageal ulcerations. It is, therefore, logical to suppose that the stomach contents are a factor in the production of these ulcerations. Ulcerations of [jathology other than that of those enumerated occur rarelv. When an unexplainable ulcer is found, especially if fungating a buried foreign body should be thought of. The treatment of inflammation and ulceration, consists in removal of the cause, be it local or general. Then topical applications of argentic nitrate, arg^rol, glvcerole of iodin or of tannin will be beneficial. If 1-22 NEUROSES OF THE ESOPHAGUS. the lesion be circumscribed, the apphcations should be made with a dossil of cotton on a sponge holder. In the treatment of peptic ulcer the gen- eral methods advocated for gastric ulcer are useful, but they are of only secondary importance to the direct application of silver nitrate, argyrol, etcetera, to the ulcer under direct inspection of the eye, looking through the esophagoscope. Bismuth powder may be blown directly upon the ulcer by means of the extra drainage tube. The ulcerated surface should first be cleaned off with a dossil of cotton dipped in hydrogen perqxid solution. There is no danger of either perforation or of hemorrhage from these procedures if the manipulations be gentle, and guided by the eye through the esophagoscope. There is great danger from blind poking with a bougie, especially in these lowly situated ulcers, as reflex spasm from the presence of the tube is apt to close up the lumen ahead. Neuroses of the Esophagus. Spastic neuroses have already been touched upon. Sensory neuroses, including hyperesthesia, anesthesia, and para- esthesia exist, but careful esophagoscopic search often reveals an anatomic basis, such as an ulcer, a scar, or an inflammatory area, in cases in which theretofore a diagnosis of neurosis had been made on the anamnesis and sounding. The symptoms complained of are usually of a vague char- acter as of contraction, itching, sticking, pricking, uneasiness or irritation, or of a foreign body or crawling insect. Exclusive of hysteria, sensory neurosis of the esophagus will be found exceedingly rare. In almost all cases of anamnestic similarity will be found to be anatomic, not purely neurotic in origin. The treatment is by very mild galvanism locally, using the inter- rupted current, and general treatment and regime as deemed best by the internist or neurologist. Paralysis and Pareses oe the Esophagus. Tlie symptoms of defective inervation of the esophagus point very markedly to esophageal trouble. All solid food is swallowed with diffi- culty ; fluids are usually swallowed freely. In some cases even fluids re- fuse to go down except in very small quantities. There are pain back of the sternum after eating, regurgitation of food and mucus. With a history of trouble of this magnitude one is apt to expect the esophagoscope to meet with obstruction to its passage. Exactly the reverse is the case. It readily enters the introitus and passes on down into the stomach without the slightest resistance, going as readily without an anesthetic as it would in the normal esophagus with the deepest general PARALYSIS OF THE ESOPHAGUS. 123 anesthesia. Tlius the (Hagnosis is estaWished. In spastic stenoses we find the spasm if no anesthetic be used, while in anatomic stenoses we find a stricture uninfluenced by anesthesia. The paralysis may be ocularly demonstrated by Stark's pill experiment. With the aid of an csophago- scope and forceps a pill or capsule is deposited in the esophagus at a dis- tance of 27 cm. from the upper teeth. If the peristalsis be normal the pill will be carried downward into the stomach ; if the pill remains where placed it demonstrates a paralysis or at least an abnormal feebleness or atony of the esophageal musculature. The causes of paralytic conditions of the esophagus include central and peripheral nerve lesions, most common being bulbar paralysis and neuritis, including diptheritic, alcoholic and lead palsies. TTie treatment of these conditions is usually not esophagoscopic, but general. Local electrical applications are beneficial adjuncts. It must be confessed that we know but little of esophageal neuroses and much remains to be studied esophagoscopically. For this purpose all clinical material should be availed of, and experimentally the dog may be used, double vagotomy, being done under chloretone and morphia anesthesia. CHAPTER XVI. Foreign Bodies in the Lsophagus, Considering the brilliant achievements of esophagoscopy in the re- moval of foreign bodies from the esophagus, it is time to pronounce the prevalent use of the sound, the vertebrated forceps, the coin catcher, the bristle and the sponge probangs obsolete, dangerous, unsurgical and ut- terly unjustifiable. There are numerous cases on record of fatal results from their use, and there are many times as many cases that have never been reported. The author has seen in consultation two fatal cases from attempted extraction, both unsuccessful. In one case a sound (with stilet) had been pushed through the thoracic esophageal wall in an efifort to push a peach stone downward, and in the other, the esophagus had been ripped open by a coin catcher. A number of instances of shock from esophageal wounds have been observed by the author, and many cases of minor wounds. (Fig. lo, Plate III.) Even the sound may make dangerous wounds by forcing a sharp or pointed body through the eso- phageal wall. Equally erroneous and dangerous is the practice of making light of the patient's fears, and the telling him that if he has swallowed anything, it will go on downward without doing any harm. Some things will, and others will not. Pointed and sharp objects, as a rule, lodge, perforate and often prove fatal. Smooth round objects, such as intuba- tion tubes, usually pass without difficulty. Coins are very prone to lodge, though usually in a vertical position, so that they allow food to pass. In one case of the author's a penny remained in the esophagus of an i8- months-old child for two months and eroded through into the trachea. The anamnesis is unreliable and misleading. The patient often does not know that he has a foreign body, but comes for difficulty in swallow- ing. In infants the swallowing of the foreign body may not have been observed. Tlie little patient is taken to the physician for regurgitation of food, or as in one case of the author's for respiratory difficulty, which arose from perforation of the foreign body from the esophagus forward into the trachea. Often patients will sav thcv no longer feel it when the ESorii.nnTis. i-5 foreign body is still in situ. Still nmrc mislca.ling is the patient's localiza- tion. The corpus delicti is very rarcl> located where the patient assures us it is. The Roentgen ray is much more reliable and its aid should be avaded of in every case. What has been said in a previous chapter in regard to the rav in the diagnosis of foreign bodies in the air passages, applies equallv well in relation to the esophagus. It may be well here to em- phasize a statement there made. In no case should a negative radiograph deter one from making an esophagoscopic examination, if the anamnesis or the symptoms justify a suspicion of the presence- of a foreign sub- stance. In a number of instances the author has been rewarded l)>- success in the face of a negative radiograph. In other instances he has found lesions of the esophagus due to long standing disease attributed to a supposed swallowing of a foreign bodv. In ,Mie instance the patient complained of the lodgement of a chicken boiu- which she located back of the sternum, where she could feel it every time she swallowed. fpon gastroscopic examination an old ulcer was found just above the cardia, and another on the posterior wall of the stomacli. As suggested bv Dr. Clement Jones, who assisted at the gastroscopy, a large l.iolus of food in passing the ulcer had produced a sensation of pain which had since persisted, and which had been wrongly attributed to a supposed bone. The matter of anesthesia is governed by rules elsewhere given. Local anesthesia is sufficient, though as a rule, a general anesthetic is better in all cases free from respiratory difficulty, which complication is more frequent than might at first be supposed. In ad.lition to edema of the larvnx from previous blind groping attempts at removal, there may be mechanical obstruction of the trachea from pressure of a large body or from inflammatory exudates in the tracheo-esophageal wall, or possibly feebleness of the respiratory movements from pressure of the foreign sub- stance or inflammatory exudates upon the vagi. When a case suspected of a foreign body comes to the author, a regular routine is followed. After taking the history, the nasopharynx, fauces, pillars, tonsils, the back of the tongue, gloss-epiglottic fossae, larvnx. and all parts of the upi)er air passages accessible are ex- amined with the mirror and brushed with a cotton moii. If nothing is found the case is sent to a Roentgenologist and a plate is made (the fluoroscope is not used). If no foreign substance is seen and the symp- toms and anamnesis warrant the case is esophagoscopized ; and, if noth- ing is found, the trachea and larger bronchi are examined in some cases, if'"'the foreign bodv supposed to be present is small enough to pass the glottis. If the radiograph shows the foreign bodv to be in the thoracic 116 ESOPHAGOSCOPY FOR FOREIGN BODY. esophagus, there is a great temptation to put the esophagoscope down at once to the point located. This would be a mistake. The tubular specu- lum should first be used to examine the pyriform sinuses and all the neighborhood of the introitus. The necessity of this is shown by a case referred to the author by Dr. Pool. While we were esophagoscopically searching the thoracic esophagus at the level of the fourth dorsal vertebra, where the pin was when the radiograph was made by Dr. Boggs, the as- sistant picked the pin out of the mouth with the fingers. Possibly it had been regurgitated by the retching incidental to the application of the local anesthetic. Be this as it may, it emphasizes the rule to examine seriatim all the surfaces from above downward. This pin might have escaped into the air passages. Another reason for the rule is that lesions weakening the walls or exposing vessels may exist coincidentally or as a cause of the symptoms of a foreign body when none exists. The only safe and certain way is by careful, orderly procedure to examine all tissues. The technic of the passing of the esophagoscope is given under "Gastroscopy." As a rule, the finding of a foreign body in the esophagus is a very easy matter. It is possible, however, for it to get so buried in the swollen mucosa as not to be visible. In one case referred to the author by Dr. Day a double-pointed pin (D Fig. 63) was buried out of sight, having penetrated beneath the mucosa and having wandered from the point of entrance. Even in such a case patient search is usually suc- cessful. The same may be said of foreign bodies lodged in diverticula. When found, the foreign substance may be so large that it cannot be ex- tracted through the esophagoscope. In such a case the tube, forceps and the intruder are all withdrawn together. The foreign body may be so sharp or so angular or pointed that to remove it involves serious risk of wounding the esophageal wall. If the points cannot be covered by withdrawal into the esophagoscope, the substance in some instances may be divided and removed in sections. In the case of an open safety pin with point downward, a hook or forceps may be used to draw it into the esophagoscope. If the point is upward (Fig. 64), it may be possible to draw the point into the tube mouth with the forceps, to turn the pin with a hook inserted in the ring of the spring end. This, however, involves some risk of forcing the point through the esophageal wall. A safer plan is to close the pin. The credit of having first done this belongs to Mosher. The ring of the instrument (Fig. 27) is inserted and insinuated into position below the pin which is then pushed into the ring with the pronged instrument. The author has modified this instrument to facilitate its introduction. The ring lies in the same plane as the stem during introduction, and is FOREIGN BODIES. 127 Fig. C3. — Foreign bodies removed by esophagoscopy aud gastroscopy. (From the author's collection.) C, I'in lemoved from esophagus of pregnant woman aged 23 years. Cocain. F, Safety pin from esophagus of 9 mouths' old infant. Chloroform. E, Forceps jaw removed from the stomach of man aged 32 years. Ether. A, Cufl" bntlon removed from esophagus of 4 months' old infant. Cocain. G. Joint of carpenter's rule removed from esophagus of boy of 7 years. Cocain. 128 FOREIGN BODY IN THE ESOPHAGUS. turned to a ris^ht anisic after ii has reached a [xiiiit below tlie pin. If the ring of the needed size for tlie narticiihir ])in is too large for introduction through the esophagoscope. the closer may be started in first, and the esophagoscope "threaded" over it, or the esophagoscope may be started alongside the stem of the closer. Tn tlie latter case care must be taken that the combined diameters of the closer and the esophagoscope do not exceed the safe dilatability of the esophageal lumen. Fig. G4. — Open .safety piu in osopliagiis Part III. GASTROSCOPY. CHAPTER XVII. History of Gastroscopy. \Mien the author first obtained gooil endoscopic views of the stomach he thought it had never been attemjotcd before. But a search of the hter- ature brouglit to hght several previous attempts. Nitsc and Letter. The first recorded attem]5t to construct a gastro- scope was by Mr. Leiter and Dr. Nitze, whose names are inseparably con- nected with the cystoscope. Both before and after this time attempts to construct flexible and jointed instruments containing optical apparatus failed in the mechanical stage. Tvouvc. in 1873. perfected a "])olyscope" (Fig. 65) with which Col- lin, of France, demonstrated endoscopically the functions of the stomach Fig. (!•■>. — The "Polyscope" of Trouve. HISTORY 01' G.ISTKOSCOI'V. 181 of a bull, and with whicli Ledcntn and Raynaud diaiincisticatod a cicatri- cial stricture of the esophagus near the cardia. Mikiilic::. in 1881, started on the l)asis that a gastroscope must be ris^id. but after rejjcated trials he came to the conclusion that a straight rigid instrument could not be passed into the stomach on account of the physiologic curve of the vertebral column, to accommodate his instrument to which, he gave the instrument an angle of 150° at the junction of the ventral and middle thirds. (Fig. 66. ]•".) This angle prevented a rotation Fig. iii> — .MiUulicz's gastroscopo. of more than 180° within the stomach, so that two complete instruments were necessary with windows o]iening in opposite directions as shown m Fig. 67. T'o touch the gastric walls means to fog the window and dim the image. The Mikulicz gastroscope was ^.5 cm. long and 14 mm. thick. The light was furnished bv a platinum loop at the ventral end which shone through a window in the side (Fig. 66, B). The loop was sup])lied with current b\- wires entering at C. and was kept cool by water circulating through two canals in the wall of the tube, the entrance and exit being shown at D. .\ third canal in the wall of the tube, with an exit at L' was for inflation of the stomach with air pumped in at L. ( )ne did not look directlv at the tissues, but an image was projected outward through a ter- 132 HISTORY OF GASTROSCOPY. restrial telescopic optic apparatus with the aid of two prisms, one at E and one at F. To prevent soihng the window during introduction, a sHde is attached at H, operated by a hand-piece J, b)' which the window is un- covered after the stomach walls are distended. Mikulicz arrived at the conclusion that a straight instrument was absolutely impracticable ; that it could be passed as far as the cardia, which he believed to be located at the eighth or ninth vertebra, where it encountered an insurpassable obstruction in the subjacent vertebra. His straight experimental staff never really reached the cardia at all. What he encountered was the constriction, anatomic and spasmodic, at the hiatus diaphragmatis and the subjacent esophageal curve. Later Mikulicz tried to adapt to gastroscopy his method of passing the esophagoscope, by which, instead of a mandrin he introduced a flexible bougie, the distal Fin. 67. — Mikulicz's gastroscope in stomach. Dotted lines show the necessity for right and left instruments. Center instrument does not show its bend. end of which protruding lo cm. beyond the esophagoscope, piloted tlie lat- ter in. He did not succeed in thus piloting the gastroscope. Mikulicz used morphin anesthesia and placed the patient on a table in lateral horizontal position, first one side then the other, according as the right or left gastroscope was being used. In quite a proportion of cases Mikulicz was unable to pass his gastroscope into the stomach. He tried chloroform, but states that under partial anesthesia the reflex irrita- bility seemed to be so much increased that he could not get his instrument even into the esophagus ; while under deep anesthesia he was afraid ta pass it lest it might prove dangerous from pressure on the trachea, larynx or other parts. Mikulicz's examinations were mostly on healthy persons, as he thought the normal was to be studied first, and he seemed to doubt the safety of examining the stomach in serious disease of this organ. W ith one exception he did not record the appearance of any MIKVLICZ'S GASTROSCOPE. 133 lesion within the stomach, and his description of the normal is very meagre and unilhistrated. After 1883 no account of the use of gastroscopy appears in literature for 12 years, and the procedure was evidently abandoned by its originator. Rosenheim, in 1896, reported experiments with a gastroscope 12 mm. Fig. 68. — Mikulicz's gastroscope iu situ, bility of passing a straight instrument. Drawing by Mikulicz to show impossi- in diameter, 68 cm. in length. It was made up of three concentric tubes, the inner (i, Fig. 69) being a terrestrial telescope of 60°, with the addition of a prism below the objective, a different prism to be substituted to inspect different areas as shown in Fig. 70. the optic tube being withdrawn for the purpose. External to the optic tube is the intermediate or illuminat- 134 ROSENHEI.]rS .GJSTROSCOPE. ing tube, containing a window, F, behind which is the electric lamp, S. Above this window is an opening closed b}- the prism of the optic tube. Four canals run in the walls of this intermediate tube (2, Fig. 69) ; two for water (CD.) circulation to cool the lamp, (water at 40° C to prevent condensation on the glass surfaces being required) ; a third canal for con- 3. t Fig. 00. — Itoscnheim's gastroscope. 1, Optical apparatus. 2, Cooling water jacket. 3, Casing to keep wimlow clean during ii.trodiiction. S, Lamp. G, Itubber tip. G. Rigid exploratory staff, hard rubber. ducting wires : and a fourth canal beginning at L and ending below F, for the purpose of inflating the stomach with air. Tlie external tube (3) serves two purposes ; a measure of depth by its scale markings, and a protector to prevent soiling of the window and the prism during introduc- tion, the external tube being turned after introduction so that its windows IflsrORV OF G.lSTROSCOPy 135 mav correspond to those of llic i)]itic ami intcrmcclialo tul)i.s. all three be- ing- known to be in line when the knobs on the external llans'es of all three are in line. The stativ ( l-'ii;'. 71 ) holds the snpply and escape vessels for cirenlating- water and the l)attery. Rosenheim tried to (Hs]iense with the water eircnlation, bnt the .^reat heat nf the platinnm filament lamj) con- fined in a closed instrnnient threateneil canterization of the nnieosa if lighted for longer than ten seconds. In addition to the straight gastroscope, Rosenheim stales that in Si)nie cases the spiral twist of the lower esophagns required an instrument bent at an angle of i()0° at a point 7 cm. from its distal extremity (6, Fig. 69). He also used a straight rigid stai? of the size of the gastroscope to ascer- tain if it were possible to pass his gastroscope in the particular ease, and if possible to nieasnic the dist?nce that the gastroscope will have to be introduced. He also used a straight sound to overcome the reflex excita- liilitv in ditficult cases. This straight sound could be intrdduced in only Fid 70. — Itusinilu'im".s ga^troricope iu stomach, showing need for prisui.s of dif- fei-eut degrees. about 70 per cent of his eases. He found that various bends and curves were necessarv and in some instances lie used a corkscrew-like twist, throwing the longitudinal axes of parts of the instrument above and be- low the bend out of the same plane. A very significant' fact is that after the beak of the instrument entered the stomach the straight part followed readily. His whole trouble in introduction was that his instrument was not designed to be passed by sight. He used cocain anesthesia applied with an esophageal syringe. As to results, Rosenheim states that gastroscopy is impossible in tumor of the stomach, and that it is contra-indicated in ulcer. Rcividcof, in 1889, reported results with a modified Rosenlicini gas- troscope which he passed through a previousl)- introduced flexible rubber tube. 136 HISTORY OF GASTROSCOPy. None of these early workers has left us any drawing of what he saw, and the written descriptions are hopelessly meagre. The procedure has been entirely abandoned. The cause for the failure and abandonment of gastroscopy may be summed up in two words : Impractical instruments. At the door of the Nitze cystoscopc must be laid the blame of the practical failure of gastroscopy up until the present The attempt to adapt the cystoscopic principles to the totally different conditions in the QESORVOIP J\ BATTERY ^1 \ WATER TUBES Fic. 71. — Stativ for Rosenheim's gastroscope. stomach resulted in the misdirection of the earnest, able, scientific efforts of Mikulicz, Rosenheim and Rewidzof. T'he instruments were difficult of introduction. The optic apparatus absorbed light and yielded a feeble image, which soon disappeared alto- gether from soiling of the window every time it touched the mucosa. For the same reason the apparatus could not be greased for introduction. The optic apparatus, furthermore, prevented the passage of the in- struments by sight, it prevented the wiping away of secretions and the HISTORY OF GASTKOSCOPY. 137 probing of suspected areas, without wliich little or nothing can bo learned. The stomach had to be empty, which it never is. All failed to recognize the mistake of trying to see a large field in a dilated stomach. The field must be traversed in the collapsed state of the stomach, fold by fold. These things are not said in criticism, for, while the work of these pio- neers was of no help to the author, as his work was done before he learned of their lalxirs, yet they have rendered great aid, as we now know by their lack of success, tliat cystoscopic methods are not adapted to gastroscopic work. This would certainly have been tried by others, and nuich time and thought consumed by some one. ]\Iikidicz himself recognized the com- plexity of his apparatus. He said : "There remains no doubt but that the instruments, as well as the method, furnish ample room for improve- ment and simplification." The simplification, I think, has now been reached, though of course, there is still ample room for improvement. The steps in the development of gastroscopy are these : ^Mikulicz determined one point, namely : that a gastroscope must be rigid, but he gave it a bend. Rosenheim went a step further and said it must not only be rigid but should be straight, though he failed at times to introduce it without a bend. Now, I think, we are ready to add four more dicta: 1. Optic apparatus must be abandoned. 2. The tube must be passed by sight. 3. Tlie stomach must be examined in a collapsed state, to permit of mopping, palpation with the instrument, probing, and combined endo- scopy and external palpation. 4. General anesthesia is indispensable to prevent retching, during ■which the diaphragm clamps the tube, rendering exploration impossible. CHAPTER XVIII. The Usefulness of Gastroscopy. (jastroscopy is not simply a feat. It has a field of usefulness that will increase as our skill and knowledge increase. Naturally, the ten- dency of everyone is to say that only in the obscure cases will gastroscopy be needed. Yet this opens a gap for the loss of the opportunity for an early diagnosis of malignancy, and pre-cancerons conditions. ^^'hen the gastroscope shall have reached its deserved recognition, patients will be examined gastroscopically sufficiently early to give the abdominal surgeon a fair chance. Better still, a positive diagnosis of pre-cancerous conditions vviill be made sufficiently early to enable him to save lives now being lost through reluctance of the patient to submit to an exploratory operation. Gastroscopy is not a substitute for exploratory celiotomy in every case. Every surgeon knows the number of cases of malignant disease of the stomach that are fatal because the patients have refused an explora- tory operation in the early curable stages. A large proportion of all cases of merely suspected malignancy will refuse to be (as they express it) "cut open to see what the matter is." They start out to find a man who can make a diagnosis without "cutting them open," and they soon find one who will give them the comforting assurance that they have no cancer and only need a little treatment. Thus their last opportunity is lost. If, however, it is proposed to pass an instrument through the mouth, consent will rarely be refused, especially when the patient realizes that one is going actually to sec the conditions present. Indeed, the author has been begged in two instances by hopeless cases of cancer to examine them. He deemed examination inadvisable, lest their impending death might be attributed to the gastroscope, which at this stage should not be subjected to more than its share of criticism. That the diagnosis of malignant disease of the stomach by symptom- atic and chemical data is not always easy, even in the later stages, is shown by the following quotation from Riegel : THE USEFULXESS OF GASTKOSCOFY. i;!9 "There is another class of cancer cases in which the symptoms that are ordinarily considered characteristic for carcinoma are absent, but ,n wh>ch dyspeptic disturbances, loss of appetite, belchin;, and general weakness appear. 1„ view of this, it wotild seem diffictilt by the common methods abso- hitelv to excltide carcinoma in a patient past thirty years of age. All such cases tlien would seem to justify gastroscopy, rather than to be con- fronted with the neeessit^■ of revising the diagnosis later after treatment on the basis of a benign condition has failed to cure. By that time the patient will have become hopelessly inoperable, and his death will be due to the lack of an early diagnosis. And this from Satmdby : ••Since the era of stomach surgery we havejearned how latent in certain •cases the characteristic signs of cancer may be." ^\■hen the diagnosis is made from a palpable tumor, cachexia an at present is the limited value to be placed ttpon negative results. Any lesion, if it exist in the explor- able area can be seen and. if advisable, felt, with the probe, and its nature determined ; but if no lesion be found we cannot be certain that none exists in the unexplorable area. However, with improvements m technic this unexplorable area will be diminished. When the gastro-enterologist shall have put the instrument into fre- quent use. it is reasonable to expect that our knowledge of the physiology and clinical pathology of the stomach will be greatly enlarged. In peptic ulcer the gastroscope is of great service both for diagnosis and treatment. Forcii^n Bodies. The feasibility of removing foreign bodies from the stomach has been demonstrated by the author. Any foreign body, the sharp points or edges of which can be guarded by the forceps or by the end of the tube, so as not to lacerate the esophagus, can be removed from the stomach with the aid of the gastroscope. CHAPTER XIX. Instruments for Gastroscopy. The Gastroscope. To examine the stomach requires frequently an 80 cm. tube, though for many cases a 70 cm. length is sufficient. It is impossible to illuminate a field of view at this distance by any form of light projected in through the proximal end, for while the loss of light is not, with parallel rays and a polisVied interior, as the square of the dis- tance, there is too great a loss for practical work. Kirstein's light, though excellent for other purposes, is useless for this great length. In addition to the loss by distance, there is the loss from slight springing of the tube and from bubbles in its lumen. These, while not interfering greatly with vision, do cut off much of the light projected in. With the gastroscope shown (Fig. 17), the length of tube is immate- rial. Tile view is as good at the end of an 80 cm. tube as that of a 45 cm. esophagoscope of the same diameter. The construction of the instrument is the same as the bronchoscopes and esophagoscopes devised by the author. In the wall of the gastroscope, as in the esophagoscope, there are made two small auxiliary tubes or canals. Both of these canals open into the main tube close to the distal end. One canal ends near the handle in a tip for the attachment of rubber tubing connected with the aspirating apparatus. This keeps the field clear of all fluids, and prevents smearing of the lamp. Large quantities of fluids have to be pumped out of the stomach in some cases. The other canal is for the light carrier, which is a small removable double conductor carrying the lamp to the distal end of the instrument where it sheds its light at close range at the point where needed, leaving every object between it and the observer's eye in darkness. The diameter of the lumen of the adult gastroscope is 10 mm. Many cases will permit a larger tube than this and die author uses frequentlv a tube whose outside dimensions are 11 mm. in one diameter bv 14 in the other. IXSTRUMEXTS FOR GASTROSCOPY. 141 The distal end of the instruniciiL is funned uf a thickened ring to prevent injury to the tissues. The exterior of the tube is not graduated. The depth is measured with a steriHzed steel rule by noting the distance between the proximal end and the upper teeth. Thus, 80 — 20=60 centimeters. An obturator or mandrin witli a projecting conical end is fitted to Fig. 72. — The Clement Jones bougie for facilitating the introduction of the gastroseope. facilitate the passing of the inferior pharyngeal constrictor, especially for those unfamiliar with esophageal work. At the suggestion of Dr. Clement Jones, the Kny-Scheerer Co. have made a sound of 90 cm. in length (Fig. yz) to facilitate the introduction of the gastroseope at the hands of those accustomed to passing the stom- ach tube, but who are unfamiliar with the passing of rigid instruments. CHAPTER XX. Technic of Gastroscopy. Anesthesia. Cocain in a courageous patient is sufficient so far as the pain of examination is concerned, but it does not stop the retching like deep general anesthesia. A large dose of morphin given hypodermati- callv assists. The stomach itself was altogether insensitive in the only case examined under local anesthesia by the author. Qiloroform the author considers dangerous for esophagoscopic. and especially for gastro- scopic, though not for bronchoscopic work. Deep anesthesia is absolutely necessarv to prevent retching, which is to be avoided while the tube is in the stomach, both because it might be fraught with danger, and because it stops the examination by the diaphragm clamping the tube at the hiatus. Prolonged deep anesthesia is not safely maintainable with chloroform. Ether, then, is the choice, preferably started with nitrous oxide. A little chloroform mav be given from time to time as relaxation is needed, espe- ciallv in bad ether subjects. Dr. Boyce has demonstrated for the author, that chloroform is much preferable technicall}' to ether, but this does not outweigh against the increased risk. Once the patient is anesthetized, ether and the occasional few drops of cliloroform are administered on several layers of folded gauze laid over the mouth, nose, gag and instrument. Incidentally it may be said that considerable quantities of the anes- thetic reach the stomach ; whether it be swallowed or be excreted by the gastric mucosa, remains to be demonstrated ; but certain it is that a strpng vapor is ejected from the tube into the observer's eye during examination, and this seems to be the case regardless of the n.iethod of administration. The preparation of the poticnt. is, in a general wa}-, the same as for tracheo-bronchoscopy. The essentials are an empty gastro-intestinal canal and a clean mouth. No food is allowed for twelve hours, black coffee and water may be taken within seven hours unless there have been symptoms of pyloric stenosis, in which case eighteen hours with nothing at all per os is essential. ^^^ashing out the stomach is not a satisfactory substitute for fasting. When necessarv, as in motor inadequacy, it should be done three or four TECH.XIC OF G.ISTROSCOPy. 148 hours before the gastroscopic examination, so that the remains of food or fluid will have had time to be absorbed or to pass on. The author has discovered in p^astroscopic investigations that after washing out the stom- ach there are from four to six ounces of fluid retained, pocketed off in the folds. The autlior has never seen an absolutely empty human stomach. There is always some fluid to he drained or pumped from pockets and valleys here and there. Postiirr. The author's earlier work was dune in a ])osture half way between the Trendelenburg and the horizontal, so that fluids drained away through the tube by gravity. But at the suggestion of Dr. E. S. Mont- gomery he has been using in some instances the reverse of this: that is, Fi(i To. — I'osiiioi: uf a>.sUiaiit.s, nurses, operator and patk'ut during the iulroduc- tion of the ga.stroscope. with the f(X)t of the table lowered about fifteen inches. To do this, the aspirating apparatus has been improved so that every ])ocket is pumped out as soon as entered. This permits of a comfortable seat on a stool for the operator. After the gastroscope is passed with the table horizontal, the plane of the whole table top is changed so that the head of the table is about 30 cm. higher than the foot. This would be too high for starting. The jxisition of the patient, operating table, operator, assistants, anes- thetist, nurses and apparatus during the starting of the gastroscope is- shown in Fig. j^. The diagram (Fig. 41 ) shows the positions more 144 PASSING THE GASTROSCOPE. accuratelv. These positions are absolutely essential, because of the length of the instruments. Otherwise everything will be in chaos. Passing the Esophagoscope or the Gastroscope. The first essential is gentleness. If the tube does not pass readily it is either not in the right place or not rightly directed. The tube should be well lubricated with vaseline. The proximal end should be held lightly between the fingers of the right hand, the handle directed horizontally to the right as in Fig. 74, which shows the position as seen by the operator looking down upon it. The forefinger of the left hand passes into the right glosso-epiglottic fossa, posteriorly to the lateral glosso-epiglottic fold, posteriorly to the tense pharvngo-epiglottic fold, and if possible into the right pyriform sinus. The tube then is made to follow this same route, while the finger Fig 74. — Position ol the riglit liand during tlie introduction o£ tlie gastroscope. viewed from above by tlie operator loolcing downward. slides toward the median line and lifts the tongue and anterior pharyngeal tissues upward (dorsal decubitus). When the cricoid cartilage can be reached, which is possible usually only in children, it is better to lift upon it directly (Fig. 75). When impossible, as it is usually in adults, the cartilage must be lifted indirectly by traction upon the tissues at the ex- treme point reachable, often the right glasso-epiglottic fossa. The introduction of the gastroscope is easy to one accustomed to the esophagoscope, and is readily learned by any one. Personally the author prefers itsing one index finger as a guide. Some may prefer starting the instrument by sight, without the obturator as in bronchoscopy ; others may prefer threading the instrument over an esophageal bougie as suggested by Dr. Clement R. Jones. Whichever of these methods be used, as soon as the introitus is passed the instrument must be guided by sight to make a safe procedure. v DUTIES OP THE SE.COND ASSISTANT. 14.-) The neck of the patient is bent backward to straighten tiic cervical curvature, or rather to cause the axis of llie oral cavity to approach paral- lelism with that of the esophagus. This also moves the upper teeth as nuich as possible out of the wav of the tube. In bending tlie neck the angle should be as much as possible at the upper cervical vertebrae so as to straighten the oro-pharyngeal angle as much as feasible, while keeping the pharyngeal axis as straight as it can be kept. After the tube is started the head may have to be raised (supine patient) slightly to prevent tracheal compression. Dr. Bovce has develo|)ed the details of holding the head to a degree Fig. To. — Diagramalio positiou of the left band in starting the esophagoscope or gasti'oscope. of perfection that makes all endoscopy per os easy. It is more difficult to teach an assistant how to hold the head than to teach him endoscopy. Tlie following is a description of the correct position. DUTIES OF THE SECOND ASSISTANT IN ENDOSCOPY PER OS. By Dr. John W. Boyce. In all this work safety demands that the mouth, pharynx, and esophagus be brought into a straight line, not by a crowbar like action of the tube, but by holding the head steadily in extreme extension with the mouth widely open. Not only does lateral pressure add to the operator's diflSculty, but it also en- tirely prevents any sense of what the point of the tube is touching. Trial with an unanesthetized patient will show that if the head is simply allowed to hang over the edge of the table, not only is an unnecessary strain thrown upon the ligaments of the neck, but full extension is not as well secured as by proper support of the head. It is further to be remembered that no mouth gag is absolutely self-retaining and a slight slip while the tube is in position may have serious consequences. For this reason it is best to detail a second as- sistant to hold the head and steady the mouth-gag, impressing him with the importance of the matter and his entire responsibility therein. To carry him out of the operator's way it is necessary that he shall hold the head at arm's 146 DUTIES OF THE SECOXD ASSIST AXT. length and to hold it in this position steadilj' for fifteen or twenty minntes a support is necessary. The weight of the head is so little that the matter seems easy, but if the assistant's arms are unsupported, about the time the most critical point of the examination or operation is reached his muscles will be trembling. Nor is it possible to rest him by any shift of position after the tube is started, .\fter many unsuccessful trials, it has been found that the best position is as shown in Fig. 76. The patient is drawn forward until the tops of his shoulders clear the table by from four to six inches, and the mouth- ^•V^ Fig. 70. — Position of sucond assistant and patient for endoscopy per os. caps and cover.* arc omitted better to show the positions. Gowns. gag is inserted on the left side. The assistant is placed on the right side of the patient's head on a stool of appropriate height, as though on a side saddle; his right leg beneath him in the kneeling position, his left foot supported on a stool 26 inches lower than the top of the table; his right forearm is passed beneath the patient's neck, supporting it; his right hand grasps the mouth-gag drawing it strongly backward. His left hand rests on the left knee, grasps the head strongly at or in front of the bregma, bending it backward and exerting a certain degree of upward pressure. The exact proportion of backward and upward pressure cannot be described, but is readily appreciated on trial, es- i'assim; the cisTROscorn. i it pecially it" the assistant lias actually oxperienccd the difference in sensation when the head hangs free and when it is properly supported in extreme ex- After the introitus is passed, the obturator is rcmovcrl, the cord is attached to the light carrier by the bayonet fitting, which by rotation is used as a switch to turn on and oft" the current, the rheostat on the battery having been previously reguhited to full illumination when the instruments were ])repared. Turning the ba\-onet fitting now lights up the instrument and the passing is under the guidance of the eye. the sense of touch onl_\- being used to note resistance, which if felt, means something to be over- come bv skill, not force. Once started, the passage of the instrument down the esophagus is easy if three important points are watched: 1. The instrument must have been well greased before starting. 2. The tube must be guided by the eye so as to follow the esophgeal lumen by sight. 3. The pinching of the tube by the teeth must be avoided so that the tube will be free to move as needed to follow the axis of the esophageal lumen as it is seen to open up ahead. Ik;. 77. — Diagram showing occlusion of the trachci hy faulty dirnlion of the gastroscope (or esopbagoscope). 4. The holding of tlie head must be exactly as just described by Dr. Boyce. After passing the introitiis care must be taken to raise the head of the patient slightly to prevent the tube pressing on the trachea (Fig. yj). This is readily noticed if the passing is done by sight. In finding the lumen the normal respiratory movements are of great assistance. The way often seems to be completely blocked ahead by what seems to be the esophageal wall, but with the next inspiration a lumen ap- pears in one or other quadrant of the tube, a few bubbles are seen, and the tube is readily glided along. The introitus passed, onlv two points will give any trouble. The first is at the hiatus diaphragmatis. the second the bend of the abdominal esophagus to the left. The hiatus is passed by placing the long axis of the elliptic cross section of the tube from the right posteriorly forw-ard toward the left anteriorly. This is easily done by placing the handle of the gastroscope in the direction of the visual axis of the ]3atient, if he were 148 PASSING THE GASTROSCOPE. looking forward (if erect) to the left. The axis of the hiatus is shown in Figure 59. Full relaxation assists passing both the hiatal narrowing and the abdominal esophageal bend. The abdominal esophagus is readily passed if the head and neck of the patient are moved to the right (Fig. 78) and the lumen is carefully watched and followed. The difficulty met here is very nutch like the fold- ing over of the trousers when the foot is not inserted in the right direction. If any serious difficulty is experienced in passing the hiatus, it will be found, usually, that the patient has come partially out. Upon deepen- FlG. 78. — Schema. Head and neck moved to right to reach left limit of the ex- plorable area ; also, during introduction, to pass through the hiatus and abdominal esophagus. ing the anesthesia the gastroscope will glide easily through the hiatal esophagus into the subphrenic portion if the lumen be watched for through the tube and follow^ed. This involves a lateral drag. After the distal end of the tube is in the stomach, the exploration is easily accom- plished if a systematic plan be followed. From one to six square centi- meters are visible at one time, so that a systematic plan of tube travel has to be followed to be reasonably certain of examining all portions of the ventricular mucosa. TECHXIC OF G.ISTKUSCOI'Y. 14!) There are two plans of exploration, both of which should be carried out. First the tjastroscope should be jiassed down carefully and gently to the greater curvature, inspecting the anterior and j)ostcrior walls. At times these walls do not seem to be fully collapsed ahead of the tube and one will have to be examined first, then the other. Then the tul)e is with- drawn, inclined slightly laterally in the same iilane. then pushed gently downward again in a new series of folds. This is repeated until the ex- treme pyloric limit is reached. To reach this limit the head and neck of the patient are moved to the left (Fig. 79) with the tube below the cardia. After the whole possible range has been covered in this way. we pro- FiG. 79. — Schema. IK-aJ uuJ ueck moved to left to reach right limit of the ex- plorable area. ceed to the second plan. The tube is passed down until the extremity touches the wall of the greater curvature in the extreme left of the pos- sible field. Then the tube is moved slowly along the greater curvature, but not in too close contact tiierewith. until the extreme right is reached. Withdrawing the tube a centimeter or two. the field is slowly swept again in the same plane, but at a higher level, and so on upward to the cardia. Next the deft fingers of one skilled in abdominal palpitation are called upon to manipulate the unexplored portions over in front of the tube. This is sometimes better accomplished by turning the patient on his side, 150 TECHXIC OF GJSTKOSCOPY. first on line then on the otlier. DurinL;- all these manipulations the tube must be \\ itlvlrawn witiiin the esophas^us. When the stomaeh is in its new position the gastroscope is again pushed downward and the newly available surfaces are explored. Should retelling supervene while the gfastroscope is in the esophagus, no harm will result. Init when the tulie is in the stomach, retching is the signal for immediate withdrawal of the gas- troscope until the distal end of the tube is above the diaphragm. No harm has been done in a number of the author's cases where retching has occurred with the tubal extremity in the stomach, vet it is to be regarded as dangerous in diseased conditions at least, and to be avoided in all cases. The vertical diameter of the stomach is easilv determined by meas- iirement. The depth from the teeth to the cardia is taken, then the gas- troscope is pushed on down until the greater curvature is encountered and the distance from the teeth again is taken. The diiTerence between this and the first measurement gives the vertical diameter of the stomach at this point. Care must be used that the measurements are not rendered inaccurate by pushing the greater curvature downward, which is exceed- ingly easy to do without knowing it, if the sense of touch is relied upon to determine when the lower wall is reached. If the downward progress of the gastroscope is watched through the upjier orifice, it is easy to see when the wall at the greater curvature is touched. Having taken our measurements, we then place the obturator externally parallel to the tube within and indicate to the abdominal manipulator the exact position of the lower end of the tube which he can then mark on the skin, giving thus with absolute certainty the exact location of the greater curvature of the empt}- stomach at that point. Care must be taken of course to re-steril- ize the obturator should it touch anything unclean. The smallest vertical diameter found by the author in any adult was 4 cm. (I'j inches) and the greatest 36 cm. (14 inches). There is a tendency for the gastric walls to be dragged along with the tube when the tube is moved, so that we shall not get a full new area unless care be taken. Withdrawal for a few cm., followed by re-insertion, allows the walls to regain their average place. The time required to examine the entire explorable area is about thirty minutes, if there are no interruptions. CHAPTER XXI. Area of the Stomach Lxplorable by Gastroscopy. Tt ,.av be acccpte.l as an axio.n tbat the more horizontal the stomachal posit':S;e less J,l he the e.plorable area. Thus ^-roptotu. v.n,c^ Ld infantile-form stomachs afford the greatest range. The reason tor 2t ;: atonce apparent when we consider that the lateral range ot mot.on is that of the hiatus esophageus. The lateral distance to which this hiatus can be slutted ^'"'^;- the individual being greatest in feeble, elderly, emacated patents, and vM h^S h of an^s^esia, being greatest in profound chloroform a,je. esia The antero-posterior mobility of the hiatus ,s of h tie use ( ex ep^ arS;ili^ng the pLing of the tube at this point) for the surroun.hng "scera crowd the stomach walls in ahead of the tube, and usuallv both anterior and posterior walls are visible at one tmie. The pivotal point of rocking of the gastroscope .s ---\'-- ; ^ thorax, not, as might be supposed, either at the upper thoracK ap.rtu.e or at the hiatus esophageus. ( Schema, b ig. 80. ) The full range of the upper thoracic aperture ,s --1^"^ 5;^'*^\' ; the whole head and neck laterally, as well as, n. some cases, shghtu ante ^°"^r':;dio4if"(S^tj'bl Dr. .oggs. taken in the li.ng under ethe7 how^^ rang! ofmotion of the gastroscope in th,s particular ^ase of gastroptosis. which was not a very good one for den.onstrat.on as re- laxation was not complete and the diaphragm hampered movement. '^ol^Lrilv there is no diffictdtym making the ^^^^^^ -- toward the ri-ht and the left anterior superior spnie ol the il um. He no force was used, and it was not a case of ecta.-,ii.. rFicr 8^) shows the position of the pylons m this case. ^ 'if ;i e iaphragn' were rigid, gastroscopy would be very much ban. pered I'ut ,t has. when the patient is fully relaxed under anesthesia, a 152 EXPLORABLE AREA. range of flexibility that may be averaged roughly at a 5x15 centimeter ellipse, the long axis being laterally, and a very slight antero-posterior rocking will bring either the anterior or posterior wall into view alone. In one gastroptotic stomach the author succeeded in exploring about the entire mucosal area. In one instance, a horizontal stomach, not more than one-third of the stomach could be explored. Fig. so. — Schema. Showing extreme right aud left positions. In the foregoing remarks reference is had only to cases in which the esophagus is normal. Anomaly or organic disease of the esophagus may render esophagoscopy and gastroscopy difficult or impossible. GASTKOSCOPy. l.>i Fig. si. — Radiograph of gostro-scope in two ditFerent positions, in a case of gas- ti'optosis, the patient under etiier. Sbadow of coin locates tlie umbilicus. ( Radi- graph by Dr. Russell H. Boggs. ) G.-^STROSCOPY. n rv <^^y:^.-'iyfe*yv^' >■>'->> ■ V'. .aavVaC Flo. S2. — Kadiograph of gasl roscope in position in tin' living patient. Tiilje mouth iu tlifi pyloris (gastroptosis). .Shadow of coin louatos the umbilicus. (Radio- graph by Dr. Russel! H. Boggs.) CHAPTER XXII. Difficulties, Dangers and Contra-Indications. Difficulties. When it is said that gastroscopy is easy, it is not meant tlnat no training is necessary. One does not learn ophtiialmoscopy in a day. Yet so far as seeing the tissnes is concerned, gastroscopy is the easier. There are two classes of dil^ficulties. They are toth slight and easily surmounted. One class concerns manipulation, including introduction and exploration, and the other class concerns the eye, which consists in comprehending the picture. Those physicians who have looke.l through the instrument at tUe stomach mucosa without any previous training at tube work, or at oph- thalmoscopv or microscopy, have been able to see clearly. Some of these same men have said that they cannot tell, on looking into an ear. what is drum membrane and what is canal. Naturally, those accustomed, like the laryngo-rhinologist. to viewing deep-seated mucoss with one eye, while relaxing the accommodation of the other eye, and ignoring its image will be enabled to see at a glance. His experience in intubation and in esophageal work will also make him facile at passing the instrument. By this It is not meant that gastroscopy should be done by the laryn- gologist. On the contrary, it is the province of the gastro-enterologist, The physician and the surgeon. None of these will have the slightest difficulty in acquiring the necessary technic, and manual dexterity. Lordosis, Potts disease and other morbid conditions of the vertebra: mav make gastroscopy- impossible. ' Daiii;a-s. In careful hands there is no danger other than that of ether anesthesia. In general, it mav be stated that the stomach is a very much less sensi- tive organ than the esophagus ; not .mly less sensitive in the strict meaning of the Sensation, but in the matter of efferent impulses for the production loG DANGERS OF GASTROSCOPY. of reflexes, and of congestion and inflaniinatory reactions to local irrita- tions. As the real question of importance is as to shock incident to the passing of a rigid instrument through the entire length of the esophagus, (which, a priori, would seem the only question of importance as the stom- ach is quite insensitive) a number of sphygmomanometric observations upon the author's cases were made by Drs. Boyce, Barach and Upham. Tbe analysis of these observations was published in the jMedical Record, from which the following is quoted : "Gastroscopy is apt to be done under very shallow anesthesia, and the pres- sure curve is particularly likely to be distorted by accidental circumstances, but in the four cases observed, the readings were fairly imiform, and it seemed safe to say that there is ordinarily no appreciable disturbance of the circula- tion, but that in an occasional case the characteristic esophageal fall will occur from the passage of a rigid instrument of this length. In these cases, how- ever, the pressure does not remain at the low point, but starts to rise at once and reaches the original level while gastroscopic search is in progress." Gastroscopy certainly is not as dangerous as passing a sound or tube, for all diseased spots are seen and pressure upon them avoided. Thus in malignant disease of the cervical esophagus, the natural constriction at the introitus is increased, and carelessness might force a stomach tube through, but with the rigid gastroscope passed by sight the growth at once is discovered. As stated, the tube is started with the finger, and a pre- vious laryngoscopic examination is relied upon to exclude disease of the introitus. Dysphagia without regurgitation is usual in disease of the upper esophagus ; so that in dysphagia with regurgitation we may safely conclude that the disease is far enough within the esophagus to allow the tube to be started by the sense of touch without reaching the diseased tissue. Mikulicz doubted the safet}' of examining cases of suspected malig- nancy, and doubtless he was correct, with his instrument with its bend which had to be swung with necessarily imperfect control, and most im- portant of all without seeing what the end was doing. With a perfectly controllable straight instrument unobscured and unweighted with a tele- scopic optic apparatus, the touch is gentle, certain and under full control. Suspicious spots can be seen and pressure upon them avoided. Dis- v-'ase of the abdominal esophagus, which makes a more or less sharp turn, (relative to the advancing tube) would be particularly dangerous with an instrument passed blindlv. As to the danger of taknig a specimen, the author has done so in a number of cases without any ill result. They were all cases associated with fungation. It is wise, probably, not to remove a specimen from the coNTR.i-i\Dic.rno.\'s to GASTROSCOI'V. 1">7 edge of a.:y flat ulceration, as there nni;-ht lie some risk of perforation, or possiblv of hemorrhage. The foregoing statement of dangers is based upon the utmost gentle- ness of manipulation under the relaxation of deep anesthesia; the passage of the gastroscope bv sight : the withdrawal of it within the esophagus, should retching supervene: and upon the strict ,.bservance of all the mmor details already alluded to. Confra-indicahoiis. \Miile. as stated, there is practically no danger, there are certain cases where gastroscopy is not advisable. In the pro- found cachexia of the last stages of malignancy : in the profound anemia of inanition from known or unknown cause; cardiac, pericardiac or major vascular lesions ; general or local, acute or chronic conditions associated with either dyspnoea or dropsical effusions ; the late stages of organic dis- eases, as cirrhosis of the liver, nephritis, etc. It will be noted that all foregoing conditions are really contra-mdi- cations to anesthesia. While it is bv no means certain that even in these cases there is any danger other than that of anesthesia, it is prudent to be particularly care- . iul.'m the earlv development of gastroscopy, not to risk a death that, " rightlv or wrongly, would be attributed to the procedure and not to the anesthetic or the concomitant aneurysm or other lesion, thus attaching a stigma of danger to a safe and useful procedure. CHAPTER XXIII. Gastroscopic Appearances. In describing and illustrating; what he has seen, the author wishes to ])oint out that these may not be usual or averag-e appearances. They are only descriptive and illustrative of these particular cases. Not until at least a thousand cases have been examined can any ono say what is the average or usual appearance of normal and pathologic conditions. Nor, until then, can any one properly classify the latter. This opens up an enormous field for research. There are many difficulties in the wav of reproducing the gastro- scopic views. These difficulties have been surmounted so far as possible in the accompanying color drawings which were made by the author from memory after the examinations. They are only a few of thousands of pictures. Normal. The folds of the stomach form an endless variety of pic- tures in front of the gastroscope. A hundred or more difTerent views are presented at a single examination. Not that the folds themselves vary so much, but the manner in which they are presented to the tube varies. T'here is one horseshoe-shaped form (Figs. 4, 16 and 18, Plates IV and V) that is often seen, especially near the cardia. It seems to come most often from the lesser curvature, and to be formed by the tube mouth encountering a fold at nearly a right angle to the side of the fold. In some instances it may be formed at the branching of a fold. When the tube mouth enters the cardia the folds seem to extend down- ward away from the tube and parallel with its axis, and the tube enters upon a half-open tunnel, the walls of which are formed by longitudinally arranged ridges separated by narrow and deep valleys. The sense of depth of the tunnel is difiicult to portray. Proceeding on down this tun- nel the ridges show a lateral trend and we suddenly end with a blank, sometiines mottled surface, rather flat, sometimes slightly ridged. It flat- tens and blanches as we proceed downward, for although we have en- countered the wall of the greater curvature of the stomach, we do not ^forF.^[l:^'Ts or the stomach. i')'.t realize it at once by the touch as we pu^li it on (lnwnw.'ird fur len or more centimeters before resistance is felt, if the patient he fully anesthetized. If the jiatient comes out partially and bevjins retchins;' resistance is at once felt, but less than misiht be expected. \\'hen the tul)e i.s withdrawn the di^k of tlattened stomach wall fol- lows the tube mouth in close contact to a position sometimes higher than where it was encountered. Landmarks, among' these folds, in size or direction, will be discciv- ered, probably, but as yet orientation is difficult except by the general sense of direction and distance from the cardia. This is difficult to esti- mate because of the dragging along of the walls by the tube. In addition to the change iri form of the folds by the pressure of the tube, variations are caused by the various movements. The iiwvciiiciits of the stomach are constant. The\' may be classified into respiratory, pulsatory, anti-peristaltic and peristaltic. llie latter class possibly includes different motions which further work will analyze. Of the anti-]ieristaltic movements there are two kinds, the duodenal vari- ety Ijeing limited to the pyloric end and the vomitory to the fundal half. Other movements of the stomach resulting from, apparently, the activity of its own muscular fibres, are frequently seen, and may be classed as peristaltic, but may be due to the communicated movements of adjacent intestines. Tlie respiratory movements in the strmiach are not so marked as those in the esophagus. They seem to produce alternately negative and positive pressures. They are sufficient to cause an in-and-out flow of air, the outflow being strongly saturated with the vapor of the anesthetic which is present in considerable quantity in the gastric secretions. The pulsatory movements are transmitted from the heart and to a great extent from the descending aorta. The impulses are not so strong as those in the esophagus where the aorta is crossed. The p^■lcric third is the most unstable portion of the stomach. In one instance the pylorus was surrounded by a rosette of annular folds. In another case the folds were seen to be larger as the pylorus was ap- proached. These folds would cur\-e in ahead of the tube, tlien be pushed aside by the advancing tube mouth. Finally cue large fold was moved aside and a slit something like Fig. 25 came into view. Almost imme- diately it resolved itself into a rounded opening which receded into a cup- like depression followed by the wrmkling into the tube of numerous small folds as shown in Fig. 26, accompanied by the ocuding of a dram or two of dark cloudy olive-colored fluid. This evidently was an anti-peristaltic movement, and it immediately preceded retching. This was at the apex of the interior of a hollow cone, the walls of IHO GASTROSCOPIC APPEARANCES. which the tube had followed. The question arose in the author's niinu whether this was the pylorus, or the constriction of an hour-glass con- traction, or the kink of a gastroptotic stomach. Either of the latter might show a narrowed opening lying at the apex of the interior of a hollow cone, with a reverse flow of fluid exuding, and an hour-glass contraction might show the depth beyond ; but the question was decided when the small, annular duodenal folds beyond were seen, and no doubt remained when these folds wrinkled up, came toward the tube and filled the opening. There seemed to be a degree of rh\1;hm in the movements of the py- loric end of the stomach in one case, but the author could not be certain. It was a much slower rhythm than that of the heart, the movements being a minute or two apart. Whether the presence of the tube was a factor in their production or not, could not be determined. The line of demarcation between the esophageal and the gastric mu- cosa is sometimes one of strongly constrasting color. The gastric mucosa varies more in tint than does the esophagus, probably on account of its greater vascularity. It is at times a deep crimson and then the contrast with the pale pink mucosa of the esophagus is marked. The contrast is represented by writers on esophagoscopy as much greater than it really is, because the writers have never seen it except by endoscopic tubes that use reflected light projected down into the tube from without. This brings out the esophageal margin in pale pink, while the insufficiently illuminated depths of the stomach are all in dark shadow if indeed they can be seen at all, and thus the true color of the gastric mucosa has never been seen properly illuminated. While in some cases it is a very dark, deep crimson, it is quite often verv pale pink. In one case, the color of the stomach about an hour after taking a glass of milk was crimson (Fig. i6, Plate III), due to the en- gorge;nent of active function from the presence of food. Half hour after vomiting the milk the mucosa was very i^ale. In another case, the mucosa was this same color four hours after tak- ing chicken soup, but as whiskey had been taken about one hour before this may have uifluenced the vascularity and consequently the color. There was carcinomatous pyloric stenosis, also, in this case, with conse- quent feeble motility. In many cases of foreign body in the esophagus the author has used a gastroscope instead of an esophagoscope, and after removing the foreign body has taken a look at the gastric mucosa by passing the cardia. These were presumably healthy stomachs, and from these experiences, as well as the views obtained in cases where only cardiospasm and csophagismus were found, he has come to the conclusion that \\hen the stomach is empty its nnicosa varies from pale red to pale pink, llie co'or seems deeper in GJSTROSCOPIC APPEARANCES. 161 ether anesthesias than wlun chloroform is used, prohably due to the greater engorgement of tlie stomach vessels. Possibly it may be the ether present in the stomach. It was much less deeply colored than in the two cases examined after eating food. The gastric mucosa as seen through the gastroscope presents a moist appearance, but it has a more velvety, less glistening, and less transparent look, than the upper mucosre. The visibilitv of the minute arterial twigs is a matter which affords great opportunities for investigation. Vessels are not usually visible through the gastroscope in the normal gastric mucosa when the stomach is empty, as it usually is when examined gastroscopicallv. In the instance where the author has seen vessels, there was reason to believe that recent taking of food or presence of ether itself or of ether intoxication has engorged the vessels. Yet in some cases no vessels were visible. In one case where the gastroscope was passed under cocain and morphin anesthesia for a foreign body in the esophagus, after removing the foreign body, the tube was passed on down a few centimeters distance into the stomach and arterial twigs were noted in a number of locations. There were no stomach symptoms in this case, and no secretion that lead one to think that a lesion might have existed. Gastritis. In one case the mucosa was covered everywhere with thick pasty secretions that looked like an exudate and was very difficult to wipe away. In another case the secretion was in patches. Swallowed muco-pus was seen in several cases without gastritis lying free, not adher- ing : so that tliere is no danger of confusing swallowed mucus with that of the stomach. The color of the mucosa was a darker red in one case than seemed normal, and the mucosa seemed thickeneer Stenosierung der Pulmonalartcric, zugleich ein Beitrag zur Kenntnis der Metastasierung der Uteruskar- zinoms, Deutsche Arztezeitung, Heft 21, 1901. 171 BIBLIOGRAPHY OF TRACHnO-BRONCHOSCOPY. (155) V. Schrottcr. H., Extraktion eines Fremdkorpers aiis der recliten Lunge mittelst direkter Bronchoskopie. Wiener klinische Wochenschrift, Nr. 45, S. 1196, 1902. (156) V. Schrottcr, H., Zur llierapie tiefsitzender Stenosen dor Liift- wege. Sitzungsbericht der oto-larying. Sekt. des XI\'. interna- tion. Kongresses in jMadrid, April, 1903. (157) V. Schrottcr, H., Heilung eines Falles von Pneumothorax. Sitz- ungsber. des \'ereins fiir innere Medizin in W'ien vom 9. Juni, 1904; s. Wiener medizinische Wochensclirift, Nr. 26, 1904. (158) V. Schrottcr, H., Demonstration tracheo, und bronchoskopischer Bilder mit dem Projektionsapparate. Sitzimgsber. d. \'ereins f. inn. iMedizin in Wien vom 27,. 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(294) Mackcitzic, Die Krankheiten dcs Halses und der Xase. Uber- setzt von Semon 1884 11., S. 24. (295) Mayr. K. it. Dchlcr, A., Beitrag zur Diagnose und Therapie der Divertikel der Speiserohre. Miineh. med. W'oclienschr. 1901, Nr. 37. (296) Mcrkcl, F., Uber Oesophagoskopie. \'ortrag gelialten im Stutt- garter arztl. Verein am I. Juli 1897. ^led. Korrcspond.-Bl. des wurtt. arztl. Landesvereins. 1897, Bd. 67, Nr. 29. (297) Mcrkcl. ¥.. Uber Oesophagoskopie. \'ortrag gehalten im arzt- lichen Bezirksverein I. (Stuttgart) Med. Korrespond.-Bl. d. wurtt. arztl. Landesvereins. 1898, Bd. 68, Nr. 34. (298) Meyer, Ed., Uber Autoskopie und Oesophagoskopie. Allg. med. Zentral-Zeitnng 1895, Nr. 100, S. 1201. (299) V. Mikiilic::, ]., Ueber Gastroskopie nnd Oesophagoskopie. Zen- tralbl. f. Chirurgie 1881, Nr. 43. S. 673. (300) »'. Mikiilicc, J., Ueber Gastroskopie und Oesophagoskopie. W'ien. med. Presse 1881, Nr. 45. S. 1405 ; Nr. 46, S. 1437 : Xr. 47, S. 1473: Nr. 48, S. 1505; Nr. 49, S. 1537. 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F., Demonstration eines Stein-und Glasessers. Sitzungs- ber. des V'ereines deutscher Arzte in Prag. 7. Febr. 1896. Prag. med. Wochenschr. i8g6, Bd. 21, Nr. 8. (309) Piggcr, H., Beitrage zur Lehre des Speiserobrenkrebses mit besonderer Beriicksichtigung der neuesten tliagnostischen und therapeutiscben Bestrebungen. Diss. Gottingen 1899. (310) Rcizenstcln, Zur Klinik der Speiserohrenerkrankungen mit Dem- onstration. Miinch. med. Wochenschr. 1900. Nr. 31, S. 1089. (311) Rcizcnstein, Die Besichtigung der Speiserohre vom Munde aus ( Oesophagoskopie und vom Magen aus (retrograde Oesopha- goskopie). Festschr. zur Feier des 50 jalir. Bestehens des arztl. X'ereins Nurnberg 1902. (312) Rcizc\istcin, Nachweis und Extraktion von Fremdkorpem der Speiserohre mit Flilfe des Oesopbagoskopes. \'ortr. geh. im arztl. Lokalverein Nurnberg 5. I. 05. s. a. ^lunch. med. W'o- chenschrift 1905. (313) Rozcnstcin, Ueber die Dilatation cicatricieller Stenosen der Spei- serohre mit Hilfe des Oesopbagoskopes. A'ortr. geh. am i. XH. 04 im arztlicben Lokalverein Nurnberg. (314) Roscnfcld. C, Die A'erwendung der Rontgenstrahlen in der in- neren Medizin. Allg. med. Zentr.-Zeitschr. 1896, Nr. 98, S. 1 177. Nr. 99, S. 1 189. (315) Roscniiciiii. Th., Beitrage zur Oesophagoskopie. I. Oesopha- goskopische Bilder beim Speiserohrenkrebs. Deutsche med. Wochenschr. 1895, Nr. 50. S. 836. (316) Rosenheim, Ih.. Ueber Oesophagoskopie. Berlin, klin. \\'nchen- schr. 1895, Nr. 12, S. 247. (\'ortrag mit Demonstration) ge- hal. in der Berliner med. Gesellschaft 13. Marz. 1895.) (317) Rosenheim, Th., Ueber die Besichtigung der Kardia nebst Bemerkungen uber Gastroskopie. Deutsche med. Wochenschr. 1895, Nr. 45, S. 740. (318) Rosenheim, Th., Ueber die Neurosen des Oesophagus. Allg. med. Zentral-Zeitung 1895, Nr. 98, S. 1173, Nr. 99, S. 1189. (319) Rosenheim, Th., Pathologic und Therapie der Krankheiten der \'erdauungsorgane. 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Char- ite-Annalen 1898, Bd. 23, S. 501. DESCRIPTION OF PLATES. Plate I. 1. Tracheal papilloma. Girl of 4 years. Removed through trache- oscope. Referred by Dr. Brush. 2. Tracheal compression by struma. Feeble pulsatory excursion. Man of ^^ years. Referred by Dr. Heard. 3. Tracheal compression by aneurysm. Violent pulsatory excur- sion. Dotted line shows limit of recession of bulging. Man of 60 years referred by Dr. Price. 4. Cicatrical stenotic web in trachea resulting from ulceration caused by a foreign body in the esophagus. Child 2 years of age. Referred by Dr. Ryall." 5. Scabbard trachea. Thymic tracheo-stenosis. Cured by thymec- tomy. Child of 4 years. Referred by Dr. Boyce. 6. Egg shell in edematous larynx. In situ 4 weeks. Removed by direct laryngoscopy. Infant 9 months of age. Referred by Dr. Moyer and Dr. Wechsler. 7. Button fixed in the trachea by the swollen mucosa. Whistling respiration. Boy of 14 years. Referred by Dr. Crawford. 8. Luetic tracheal stenosis. Man 24 years of age. Referred by Dr. F. T. Smith. 9. Compression stenosis of the trachea by an esophageal carcinoma. Man aged 60. Referred by Dr. Sanes. Plate II. 10. View looking down left bronchus. To the left above is the opening of the superior lobe bronclius. To' the right the inferior lobe bronchus. 11. Normal \'iew looking down right bronchus. Above is the mid- dle lobe bronchus : below to the left the inferior lobe bronchus ; to the right the superior lobe bronchus, appearing larger because nearer. 12. Fungating granulations from healing cartilage, after trache- otomy. Skin allowed to unite per priiuam. DiLSCRirriox or plates. i89 13. ]^-in,ary Irechcal ozena, (iirl aged ih years. Referred by Dr. Wallace. ^^^^^^^^^ ^^^^^^ ^^^^^^,^ cicatrices. Right bronchus of man aged 23 years. Referred by Dr. F. T. Smith. „ , , , . , IS Compression stenosis of trachea. Posterior wall bulged forward by tubercular lymph nodes. Woman aged 25 years. Referred by Dr. Schildecker. Pi,.\TE HI. 1. Introitus esophagi. Normal. Dark lino must not be understood as a gaping. Collapsed shut. Man of 36. 2. Intra-thoracic esophagus. Unusual view, but normal. More usual appearance shown in Fig. I.. Plate I\ . ... 3. Esophagus at hiatus diaphragmatis normal. Note axis of lumen. ^""T" Gcatricial esophageal stenosis. Pin-hole lumen. White scars. Recurrence of stenosis following ulceration during typhoid fever. Prim- ary lesion, burned bv swallowing lye in childhood 14 years previously. I\l'r H. aged 21 years. Referred by Dr. Stevenson. _ 5 Ibid Bottom of diverticulum. ?>Iucosa chronically inflamed. 6 Tubercular ulceration posterior esophageal wall, simulating decubitus ulcer often seen in typhoid fever. Tubercular lesion m this location is somewhat rare, though still more rarely is it diagnosticated Incidentally this figure shows the introitus esophagi when the cricoid cartilage is lifted bv the laryngeal speculum. Compare Fig. I., above. 7 Carcinoma of the thoracic esophageal wall (left) covered with normal mucosa. Lumen pushed to the right and almost obliterated. Man aged 60 years, referred by Dr. Sanes. 8 Carcinoma, endo-esophageal. Woman of 41 vears, referred for chronic nasal sinus disease. Esophageal symptoms slight and attributed to globus hystericus. 9 and 12. Fibroma papillare, attached by long slender fibrous ped- uncle Disappeared into the esophagus at times after swallowing. Fig. 12 shows the attachment within the esophagus when the cricoid cartilage is moved forward (instrument not shown). Removed through tubular speculum. ]Man aged 36 years, referred by Dr. Heard. 10. View in thoracic esophagus showing wounds (above) made by blind groping with a coin extractor which did not extract. Boy of 14 years. II. Wound in esophageal wall made by a pin which was afterward found higher up. Woman of 23 years, referred by Dr. Pool. 13. Normal. "Kink" of the esophagus at the hiatus, probably more a preventive of regurgitation than the cardia. 190 DESCRIPTION OF PLATES. 14. Peri-esophageal carcinoma overlaid with normal mucosa, lumen deviated so far to right as to be out of view. Diagnosis upon hardness of mass, and age of the patient. jNIan of 60 years, referred by Dr. Swope. 15. Stomach ulcer (on left side of right fold in the view), bed showing dark after secretions had been wiped away. ( )ther folds normal. Woman aged 26 years, sent by Dr. Moss. 16. Stomach. Normal. Branched fold. Dark crimson color. Ex- amined one horn- after drinking milk. Man of 32 years. 17. Stomach. Carcinoma. Zone of hyperemia. ]dan of 46 years, referred by Dr. Walton. 18. Stomach. Same patient. Mulbcrry-likc nudule at another por- tion of growth. Pl.vte IV. 1. Thoracic esophagus. Expiration. Xote lumen not entirely closed. Man aged 40. 2, 3, 4, 5 and 6. Normal stomach. I'olds in various positions as seen separating and collapsing ahead of the tube as it is inserted and withdrawn. In Fig. 4 is shown a horseshoe-shaped position of a fold often seen near the cardia, usually to the right. At times seen elsewhere. Compare Figs. 16 and 18, Plate V. 7 and 8. Stomach. Normal wall of inferior curvature flattened by pressure of the tube mouth. 9. Gastritis. F'old in lower right hand corner is cajiped by secretion sitnulating ulcer, before wiped away. 10. Gastritis. All folds sponged but one. which shows thick tena- cious secretion. 11. Gastric nicer seen on edge. Not sponged. Man aged 32. Pa- tient of Dr. Finkelpearl. 12. Same patient. Scar after healing of the ulcer. Scar shows yellow bv engraver's error ; it should be grayish, nearly white. 13. Carcinoma of cardia. Infiltrated but not ulcerated hard mass to right of view. Man 38 years. Referred by Dr. Haworth. 14. Same patient. Farther to right than Fig. 13, on lesser curva- ture. Fungating portion of mass. 15. Carcinoma of pylorus. Left bolder of the tumor. Man of 44 years. Referred by Dr. Haworth. 16. Normal stomach. Three cm. below the cardia. Note horseshoe- shaped fold to the right. Maid of 19 years. Patient of Dr. Lichty. 17. Normal stomach, farther down, same patient. (\'iews are never twice alike, no form is meant as t\pical of local it w) 18. Normal .'■-tomacH. Four cm. from cardia. Woman of ^t, years. DIISCRH'TIOX or f'L.ITF.S. 191 19. Normal stdiiiacli. W niiian ui 19 years. Showing diversifie