;^ '%0JllV3J0't^ ^OFCALIf '-o'AaVHaiV^ '^(^AaVtiS: iwj'.ii^i j^.' "JI3JI1V0UI • '•■Jco'Mi'irjn-" \C r i i i rr\Tt ^i ' r lit r, tt f ,. • nr * I'/^rM iilJ/MilllJU'- ■-.^IIIBRARYQ^ ^^^tllBRARYO^ %a3AiNrt-3i\v^ '%ojiivo-jo"^^ %ojnvjjo-^ %a3AiNn3\v^^ "^Aavaani^ "^^^Aavaaii^ o FCAUFO/?' i^-?m\ir. -n O ^' si ■ \~. -5^, ■ .^WEUNIVER% ^lOSANCElfj rT-l >- ' <: 9 "^ ?3 C AN APOLOGY FOR THE NERYES: OR, THEIR HFLUEKCE AND IMPORTANCE HEALTH AND DISEASE. BY SIR GEORGE LEFEVRE, M.D., FELLOW OF THE ROYAL COLLEGE OF PHYSICIANS, LATE PHYSICIAN TO THE BRITISH EMBASSY AT THE COURT OF ST PETERSBURG, ETC. ETC. ETC. " Without a nervous system there is no animal, — there can be none ; ■without a circulating one there are myriads." — Dr Macculhch on Fevers. LONDON : LONGMAN, BROWN, GREEN, AND LONGMANS, PATERNOSTER ROW. 1844. MURRAY AND GIBB, PRINTERS, GEORGE STREET, EDINBURGH. 3-f-5 2— S^S. o^ BENJAMIN TRAVERS, Esq., F.R.S., &c. &c. &c. TO WHOSE FRIENDSHIP THE AUTHOR IS INDEBTED FOR THE OPPORTUNITY OF VISITING THE GREATER PART OF EUROPE AS A TRAVELLING PHYSICIAN; AND OF SUBSEQUENTLY PRACTISING HIS PROFESSION DURING A PERIOD OF FOURTEEN YEARS IN THE CAPITAL OF RUSSIA, THIS VOLUME IS GRATEFULLY INSCRIBED. London, October 1844. 60, Brook Street, Grosvenor Sc|iiaiv. PREFACE. If "The Travelling Physician" has been censured by his professional friends for omitting all medical topics in the account of his Rambles, he is at least willing to make the amende honorable^ by the present endeavour to supply the omission. In the physiological part of this work he has con- densed the labours of others into a small compass ; and in the pathological, he has stated the results of his own experience in a northern latitude. He is doubtful whether this will be worthy of his brethren's accept- ance, seeing that the human race is, with few excep- tions, every where subject to the same diseases, and that the treatment of these is pretty generally con- ducted upon the same plan, at least in those countries in which he has sojourned. He has introduced some peculiarities of the German school, both as regards the modus medendi, and the choice of remedies. Goethe has said of book-makers — " Sizt ihr nur immer ! Leimt Zusamnien Braut ein Ragout von andrer Schinaus." Nor is it difficult by gluing together, and collecting VI PREFACE. the fragments of others' labours, to add another volume to shelves ah-eady groaning under their heavy loads. As regards physiology, opinions fluctuate as much in this branch of science as they do in chemistry, — nothing seems stable for any length of time. To reduce a matter to the test of experiment is much more easy than to reduce it to the test of truth. After the sacrifice of hundreds of animals to establish the validity of some favourite theory, it is objected to the experimentalist, that his deductions are fallacious, and then more life is sacrificed to prove that he was wronff. There is at present a leaning towards the re-esta- blishment of old doctrines. In the blood we are again to recognize all those vital phenomena which HoflPman and his disciples could not find upon making a diligent search for them, and when the more delicate and beautiful system, founded on the influence of the nerves, triumphed over the gi'oss and peccant himiours of Boerhaave. The importance of the blood in the animal economy is one of those self-evident ti'uths which require no farther confirmation. If it be not the " life thereof," it is the food of life ; but be it remembered, that without the influence of the nervous system, it loses all its powers and its vitality, which lat- ter is rather borrowed from the nerves than inherent in the blood ; and although this fluid is essential to the well-being of the nervous system, yet it is formed through the instrumentality of the latter ; for blood is PREFACE. yil not blood Indifferently to the animal in which it cir- culates ; it must be of the same kind, and elaborated by one of the same species. It is formed from chyle, by the conjoint aid of chemical and nervous agency, which must be in due force to prepare it properly, and without which its nutritive powers are insufficient for the purposes assigned them. It is usual to speak of the blood as of a viscus, which has existed in the same state from the com- mencement ; the one waxing merely in growth, the other in quantity. Now the blood is ever changing, never the same ; at no one hour of the day is it the same in the body, either as regards its quantity or its quality. Even in a healthy state, the fibrine, the albumen, the red particles, the serum, are never for any length of time in the same proportion to each other ; but when disease manifests itself, the changes become very apparent. The fibrine is in excess in inflamma- tion, and in acute rheumatism it is found in triple pro- portion to what it is in health. The red particles abound in plethoric habits, and are deficient in the leucophlegmatic. The serum increases in the same ratio that the solid parts diminish, and its saline particles are not constant in their proportions. It must be a stumbling-block to the humoral i)utho- logists, who attribute all disease to the state of the blood, that the latter is never in its normal state in Vni PREFACE. the pregnant woman, although she may enjoy the best of health dming the whole period of gestation. It is asserted by those even who strenuously main- tain the vitality of the blood, that the red particles and fibrine alone enjoy this advantage, which is denied to the serum ; yet the latter is as essential to the con- stitution of the blood as either of the former; for when the serum is expressed from them, what becomes of their vitality? Extraneous, adventitious matters may be mixed with the blood, but they do not stand in the same relation to it as the serum, which is part and parcel of it. If the blood be vital, it is so throughout ; but we lean to the opinion that it borrows its vitality from juxtaposition with the vital solids, as iron becomes magnetic within a certain distance of the magnet. It may be wasted to almost any amount, and be reproduced by the nervous power working upon fresh materials. The dehcately framed partm-ient woman, whose requiem was all but sung (life having seemed to ebb away), shall rise triumphant from her couch, when the prick of a thorn or splinter, injuring a nerve, shall prostrate the atldete not to rise again. The blood holds a most important place amongst the vital organs, if it can usurp this title, but it does not hold the first place. To it the muscle owes its power, the nerve its tone ; from it all the secretions are prepared ; but it does nothing of itself; all depends upon its vitality, which it derives from the nerves. PREFACE, IX In the further consideration of the subject, we shall endeavour to establish its full claims physiologically and pathologically, not endowing it with properties, nor attributing to it inteUigence, but giving it its due rank in its triple alliance with muscle and nerve. " The Travelling Physician" sought protection under the authority of a sliding scale for changes in opinions during twenty years of his life; and as he is well aware that a similar scale is applicable to every branch of science, he cannot but feel that a long exile may not have permitted him to keep pace with others in noting the all but daily discoveries that have been made in physiology. But if he has not learnt all that has been done at home, he may comfort himself with the idea that he will have less to unlearn. How much has proved ej)hemeral in this short space of time I Sir Charles Bell's respiratory nerves had a local habitation, and a name, in anatomical text-books and manuals. They have been erased from subsequent editions of the same works. Poisons were proved, as far as experiment can prove anything, to be introduced into the system by means of the blood. This doctrine was set at nought by other experi- ments still more conclusive than the experimentum crucis of Mao;endie. Dr Addison and ]\Ir INIorgan maintained that the nerves alone were the operating agents, and that too upon the undeniable test of experiment. X PREFACE. Other physiologists again maintain that there was fallacy in these proceedings, — the old story, — and the general opinion seems to be in favom* of absorption into the blood to account for the effects of poisons on the system. What are we to tliink, then, of the nerves, — to hear once more of a nervous fluid, visible, ponderable, palp- able, expressible from tubes, when the idea of this structure has been rejected, reviled, and proved fal- lacious, for nearly a century. If those who think they have arrived at the top of the tree find that they have again to descend to the bottom, the Author will have less cause for reproaching the frost and snows of Ilussia, which, if they prevented him from climbing so rapidly as he might have wished, may, at least, have had the merit of lessening the height from which he might have had to fall. London, October 25, Hi44. CONTENTS. ^ti f f- PART I, Introductory— Brain and Nerves— Respiration— Animal Heat, 1 PART II. The Blood, ••...... 23 PART III. Muscular Motion— Circulation— Nutrition— Secretion, . . 33 PART IV. Sympathy— Phrenology— Mesmerism— Sleep— Dreams, . . 48 PART V. Vision— Hearing— Smell and Taste— Feeling— Voice and Speech, 85 PART VI. Influence of Blood upon Nerves— Nervous Complaints— Headaches, 117 PART VII. Epilepsy— Hysteria— Palsy— Catalepsy— Hydrophobia— Trismus Traumaticus— Delirium Tremens— Hooping Cough— Chorea, 155 xn CONTENTS. PART VIII. Cholera Morbus — Scorbutus — Diabetes, . . . .181 PART IX. Fevers, ........ 199 PART X. Ill health — Nervous Coughs — Blood to Head — Ague — Moldavian Fever — Local Diseases of Nerves — Sciatica — Iritis — Knee — Earache — Affection of Jaw, ..... 226 PART XI. Homoeopathy — Instinct and Reason — Memory, . . . 251 PART XII. German Therapeutics, ...... 271 Appendix, ....... SOS ERRATA. Page 16, line 14, for plusquam, &c. read Ilominem, non ui a matre sed a novercu natum. Me Hercle . . Mehercle. their . . its. rebel . . able, effort . . effect, proves . . prove, qu'il, &c. . . qu'il dit a la cigale. La, &c. . . La maniere anglaise a trioniphd. into . . in. conglometion . . conglomeration. 76, . . 15, .. 132, . . 23, .. 156, . . 26, .. 157, . . 14, .. 161, . . 6, .. 200, . . 24, .. 277, . . 23, .. 295, . . 9, .. 353, . . 14, .. ^^ AN APOLOGY FOK THE XERYOl'S SYSTEM. PART I. Introductory — Braiu and Nerves — Respiration — Animal Heat. INTRODUCTION. There has been for some time a leaning of medical opinion to doctrines which Avere exploded, because they were considered as untenable. The coup de grace was supposed to have been given to the humoral pathology, and the views of Hoffman were adopted, and flourished on the spoils of Boerhaave. There is in all sublunary things a principle of pro- pulsion, and one of retrograde movement. It is seldom that the machine makes a dead halt for any space of time ; if it do not go a-head it falls back. Some allow themselves to be carried down the stream, finding that they can make no head against it, — a sort of voluntary compulsion. Thus, even at the present time, and in the light of day, some anti-vaccinators are to be met with, here and there, who glory in every case of small-pox, if it succeed to vaccination, and B Z INTRODUCTIOX. look forvrarcl to tlic re-establishmcnt of Variola as to a medical mlllennmm. When it was observetl by tlie political adversary of a certain premier, tliat he Avas a drag-chain to the coach, it was retorted that, but for this check on its speed, the vehicle would topple over. It is justifi- able from time to time, to look at the foundation of systems upon which so much reposes. When the late Dr Armstrong published his work on fevers, it was hailed by the pupils, and by the jvmior members of the profession, as a Newtonian system of medicine. The treatment of fevers became a matter of certainty. It was a plausible and specious com- position, which caused the most bitter disappointment to those who put his plan of treatment into practice. The author himself, previous to the termination of his career, much modified it. This popular production savoured of the humoral pathology, and has imparted this odour to many subsequent effusions. The snake was only scotched, not killed by Hoffman, if we may judge of the attempts to twist itself into life again, which it is at present makmg. There is nothing extraordinary in this. It is the fate of all systems which have less than mathematical demonstration for their basis, and such evidence has never been claimed by the professors of the healing art. The greater the excitement, the greater will be the reaction; — the collapse follows. It has been too prevalent in found- ing a new system to sink the old to the bottom, whereas much valuable matter is to be picked from a stranded wreck. There is always something good in what is old, and it savours both of ingratitude and INTRODUCTION. 3 of prodigality not to retain what may be serviceable. It is plausible to talk of laying the axe to the root, but Ave should be sure that we have planted a better tree before we fell the old one. Lopping and pruning would often stand us in better service. How much do we lament the ill considered zeal of our ancestors in defacing our ancient places of worship I When John Knox said that the only way to prevent the rooks coming again was to pull down their nests, he was thought, no doubt, to have said a very witty tiling, and told a very plain truth; but both have proved equivocal, and the rooks are again congregating and trying to repair their old nests, and the chisel and the trowel are busy in restoring those works which Cromwell's soldiers and horses so cruelly mutilated. If we could see into futurity, we should often spare ourselves much trouble. If we could be convinced that time changes all things, we should not be so precipi- tate in our actions, but trust more to its influence ; and what is more important, we should avoid reaction. Sweeping reforms introduce consei'vative principles, which merge into restorative, and these again threaten the return to the original sin. In the medical, as in the religious, world, these changes are ringing, and teachers are at work to re-establish the doctrines which once were law in the school of Leyden. If these had been more carefully examined and sifted, they might have been reformed without being wholly rejected as untenable. " The conjecture of the old humoral pathologists was not altogether wrong as to the existence of acrimonies in the blood ; but they committed an error in sup- 4 NERVOUS, MUSCULAE, AND SANGUIFEROUS. posino: tliem to be tlie cause instead of the effects of the disorder." In the present observations Avhich I have to oft'er upon these important matters, it is not intended to trace through the Avhole system of physiology the importance due to the nervous system, but to rei)ro- duce some of the most striking features which present themselves to notice in considering the relative value of the three great vital powers. THE NERVOUS, THE MUSCULAR, AND THE SAN- GUIFEROUS. If the offices consigned to the first be dispassionately considered, — if the weight of duty allotted to it be borne in mind, — if the importance of its functions, upon whose due performance the physical is connected with the moral man, be duly appreciated, there can be no hesitation in assigning it the first claim to con- sideration. In a state of health and tone we recog- nize its powers in the perfection of the five senses ; the smallest derangement of its minutest organization is accompanied by imperfect communion with the external world in any of these five modes of relation- ship. The division of a little chord, finer than the most delicate lute-sti'ing, shall prevent the eye from seeing, the ear from hearing, the tongue from giving utterance ; nor shall there be aroma in the rose, nor smoothness to the finger's touch ; — all shall be dead without, — and then the inmost soul shall wither, pine away, and die. Its importance over the vital and NERVOUS, MUSCULAR, AND SANGUIFEROUS. 5 animal functions equally preponderates. The division of two small chords shall suspend respiration ; and circulation is so dependent upon the duties of this function, that it soon ceases afterwards. In the pro- cesses of digestion, assimilation, and secretion, there is equal evidence of its prior claim to consideration. It is not so easy to test it in these latter operations by mechanical lesion as in the former ; but pathology affords us the same conclusive evidence ; and another power, of which at present we have but imperfect notions, but which offers us much that resembles the nervous, makes that evidence still stronger. Thus the nerves, which preside over digestion, may be subjected to test ; and when, by division of these, this function is suspended, it may be renewed by the substitution of the electric fluid. Moral causes come to our aid in affording us proofs of what secretion owes to the nerves. The eye, lubri- cated by the effusion of the lachrymal gland, shall be deluged with tears, or roll burning in its socket, as the mournful tale or worked-up frenzy shall operate in augmenting or suspending this secretion. The kidney's functions are increased by nervous irritation ; paralysis of the nerves, which are destined to them, as we witness in Ischuria Renalis, suspends then* action, and speedy death ensues.* Thus, tlie vessels to honour and dishonour testify to the truth of the assertion that the nerves are paramount, and it would be waste of time to multiply instances in cor- roboration of the fact. As the lord of the vineyard would gather no grapes * The ancients preserved their tears in little vessels, — Luchrymalki. 6 NERVOUS, MUSCULAR, AND SANGUIFEROUS. nor press any Avine without labourers at his disposal ; but as, under his command, one prepares the ground, another plants the vine, while a third primes and a fourth waters, and all is perfected in due season, so we should find the nerves to hold a broken sceptre, but for the agents which are in readiness to conduct the operations which they control. These are sup- plied by the muscles. What variety do they as- sume in their forms and disposal, not less so in their functions. The brawny deltoid of an athlete, the smallest fibre, stretching and relaxing the tympanum, are of one and the same structure. The sloth mounts his ladder step by step, as he lays hold of the branches with his claws, — the sky-lark soars to the clouds by one and the same means. There is a directing power ; but this would avail nou2;ht if the instrument of obe- dience W'Cre not perfect in its kind. There are the bones and ligaments, which seem to have been rather too mucli neglected by the exclusives. The little round shot of the fo wlers gun brings down the tenant of the air a humble suppliant to the ground ; the muscle no longer obeys the nerve, because it can no longer rely upon the integrity of the bone. How the web is woven, — break but a few of its meshes, and the captive fly defies the spider still. The scratch of the lancet, which shall distort the eye and render expression hideous, shall also make that seemly which was before a blemish in the fea- tures. The twig of a twig is only imj)licated in this performance, but it is muscle or its terminating ex- tremity which is the subject of experiment. " The nerves of expression" is a term somewhat in the NERVOUS, MUSCULAR, AND S.iXGUIFEROUS. 7 usurper's style. Those v;hicli direct it would be less equivocal, for they surely can of themselves express nothing by themselves. The satirist Rabener relates the history of a lawyer, the skin of whose face was so thick that he was never seen to blush. In the performance of all the different functions alluded to, we recognize as fully the co-relative aid of the muscular power to the performance of function, as of the seeming primo-motor. Where fibre is not demonstrable, function proves its existence ; and this, in some instances, in an inverse ratio with its pal- pable operative ; but, as Fontenelle observes, we have very bad eyes. Let us return to the vineyard, whose lord has hired labourers. He visits his garden, and no man is at his work, — all are prostrate, exhausted, unable to labour. He is angry ; and yet, by the appearance of things, the men have not been all the day idle. He calls his steward to explain, for none to whom he ad- dresses himself hath power to speak; and the steward replies, that since they have been in his service, they have tasted neither of food nor drink ; and that they have gradually grown weaker and weaker, till they have fainted away. Then the lord recognizes his fault and his impotency, and he orders to each a small portion of wine ; and as each begins to revive, the portion is increased ; and, after a certain time, the men are again labouring in the vineyard. Now, he who would forbid the " banns between flesh and blood," as the author of Spasm and Palsy, &c., &c., intimates that some are inclined to do, must take but a very nsvrrow view of things, and place 8 NERVOUS, MUSCULAR, AND SANGUIFEROUS. himself In the situation of the improvident lord of the vineyard. This is precisely the case with the blood, which (whatever importance may be assigned it in the ani- mal economy) is more a product of other organs than an organ itself. The horror which nature is said to have of a vacuum is not greater than that which many physio- logists had of attributing vitality to a moving fluid. Yet, as many horrors have been overcome, this also is one which has died away without producing any great convulsion in nature. It has amalgamated itself with those Avonders of which Lucretius speaks in such energetic language : " Nil adeo magnum, nee tam mirabile quidquam Principio, quod non minuant mirarier omnes Paullatim." It is said that the clot of blood becomes organized. The fibrin poured out in inflammation, in a semi-fluid form produces false membranes, which subsequently become organized. Miiller has placed the matter in its fairest and most intelligible light. A few extracts from the division 6, p. 152, will suffice : — " To regard merely the solids as living is incorrect, for there are strictly no organic solids ; in nearly all water consti- tutes four-fifths of their weight Although, then, organic matter generally be considered as merely susceptible of life, and the organized parts as living, yet the blood also must be endowed with life, for its actions cannot be comprehended from chemical and physical laws. The blood is not the only living fluid, as Spalan- NERVOUS, MUSCULAR, AND SANGUIFEROUS. 9 zani's experiments long ago proved beyond all con- troversy. " The blood manifests organic properties ; . . . there subsists between the blood and the organized parts a reciprocal vital action, in which the blood has as large a share as the organs in which it circulates."* In the important share ■which the blood has in all the phenomena of life, we have no evidence of its being influenced by voluntary power after it has been effused. It is then the rudis indigesiaque moles, nor is design traceable in its actions unless it come in contact or relation with more formative powers ; it is false membrane only which it produces ; it is no longer the organ of thought or will. The blood is the food of the system ; and, as fimctions are anni- hilated or suspended by an excess or deficiency of nutriment, as they are deranged by adventitious noxi- ous ingredients mixed with the wholesome provender, so are the nerves and muscles annihilated functionally by precisely the same circumstances, as regards the quantity and quality of their food, Avhich is the blood. This, too, not only as concerns its constitution in the same species, but in its influence upon animals of diff'erent kinds, for it is found, by transfusion, that the blood of an herbivorous animal Avill not support the lite of a carnivorous one, whereas the blood of two animals of the same species may be exchanged with impunity. The nerves and muscles must form the blood Avhicli can alone invigorate them. Here, then, we come at once to the dependencies of the nerves, muscles, and blood, upon each other ; and it is in vain to attempt to isolate them in their mutual influences. They are * MuUer's Physiology. 10 BRAIN AND NERVES. collaborators in all the functions of life, but they are not co-equals. As futile would it be to attempt to separate mind from matter in our present state of limited knowledge; yet matter is not mind, nor is muscle will, nor blood life, nor brain thought, yet these are to life what matter is to mind. We can substitute excitement, which shall rouse irritability in muscle and nerve, but was mind ever supplied by galvanism? The human species may possess a higher power than the rational ; for this is not to be denied in many of its functions to the brute.* Instinct is common to both, nor sufficient for either. The Vicar of Harrow, in his " World without Souls," has put to nought the satire of Monboddo, " that men are monkeys with their tails rubb'd off." BRAIN AND NERVES. In contemplating, the organ of the brain, the care which nature has taken, and the provision which the God of nature has made for the preservation of this most beautiful structure, we have ample evidence of its importance. We are reminded of the parallel which Paley draws between human and Divine works ; whereas, in the former, there is ever an aim to ap- proach what they never reach, viz. perfection; so, whatever proceeds from the hand of the Creator is so perfect in all its parts, whether in great things or * Les animaux deviennent fous et enrages. S'ils n'avaient point de raison pourraient-ils la perdre ? — Dc Wsiss. BRAIN AND NERVES. 1 i small, that all the combined efforts of human skill could not make the slightest improvement. The organiza- tion of the gnat is as complete as that of the camel, nothing is forgotten, nothing omitted in all the infinity of creation. In examining the bony receptacle in which the brain is placed, "sve find the wall built up the strongest ^Yhere it is most hable to injury from accidental causes. Its spherical shape is also a great safeguard. Triple membranes cover the convolutions, the external and strongest of which dips down and separates the hemispheres from each otlier, and, expanding below, places a shield between the great and little bram. These membranes prevent the pressure of the tAvo parts of the organ upon each other. In the arrangement of the vessels, every care is taken that the circulation should meet with the least possible impediment, so that congestions of blood, so detrimental to its functions, should be avoided ; and as the vessels themselves are of more delicate struc- ture than in other parts, and are bent at their entrance into the cranium, the impetus of the blood is thus diminished. The same care is taken of that part of the brain which is lodged in the spinal canal. This is surrounded by thick layers of muscles, and on its dorsal side the spinous processes of the vertebra form a chevaux de /rise for its defence. In mass the brain is the largest organ, with the exception of the liver, hi the whole body; and in the human subject, as regards its surface, is more extensive in proportion than that of any other animal. It is not intended to enter into its minute anatomy. 12 BRAIX AND NERVE&. In oiu" dissections of this organ, we must feel dis- appointed at our ignorance of the functions of its different parts ; but we cannot but admire its beauti- ful and delicate structure, and an instinctive feeling would lead us almost to exclaim, If mind can emanate from matter, here must be its seat. Minute dissection has done much of late years towards the better know- ledge of the functions of its different parts. Its fibrous texture, insisted upon by Dr Gall, and now generally recognized as correct, clears up many of the difficulties which before presented themselves in some of its diseases, and a more wonderful effort still remained to unfold its double structm^e. In this the wisdom of the Creator is not more apparent than his goodness, which is here lavished with unbounded hand. To the moralist, as to the physi- ologist, this proves of the greatest importance in clearing up so much mystery in the history of its functions. The weight of the brain is estimated by Dr Sims at 46 ounces in the adult. Dr Elliotson estimates the .spinal chord at 1^ oz., and the nerves a few ounces more ; so we may state the nervous system of the adult to weigh 50 ounces. Dr Macartney declares he has ascertained the real nervous substance to be so inconsiderable, that he thinks " it is perhaps not assuming too much to suj^pose that the whole nervoue system, if sufficiently expanded, would be found too tender to give any resistance to the touch, too trans- parent to be seen, and probably would entirely escape the cognizance of all our senses." Besides the brain and nerves, there is a third system BRAIN AND NERVES. 13 named the o'ano-lionic. It has been a matter of con- troversy, whether the spinal chord issue from the brain, or the latter be a termination of the former. Some anatomists have asserted that rudiments of the chord are found in the embryo before any trace of brain can be discovered. It is now generally admitted that neither the chord arises from the brain, nor the nerves from the cliord ; for in acephalous foetuses the chord exists. " We must not forget," says Dr Elliotson, " that every part of the nervous system throughout the body is directly connected with others, and in- directly with all the rest, just as every blood-vessel with regard to its system." It is maintained that the nervous system is equally diffused, equally sentient, equally perceptive, tliroughout the whole body. Now these powers are not the same in the nerves and in the brain. The brain is not in the little finger, but the latter is in the brain. A circumstance of common occurrence warrants the truth of this assertion. A man feels his digitals for months after his limb has been amputated ; the impression is so strong that nothing but the assistance of his other senses can convince him that he does not feel the fingers or toes, which, perhaps, he has left in another hemisphere. Perceptive sensation is in the brain, and to whatever region pain may be referred, it has its real seat in the brain. If the nerves be divided, the functions of the parts to which they are distributed cease. If the optic nerve lose its power, the eye no longer sees ; deafness is caused by injury to the auditory nerves ; the division of the phrenic nerve suspends respiration ; the tongue is speechless when the recurrent nerves 14 BIIAIX AND NERVES. are cut. Of the blood's vitality there is no doubt, but we believe this is imparted to it by the nervous system. This is as fully developed in the foetus in utero as in the adult, so that its presence is as neces- sary to the vitality of the child as of the mother. If brain and spinal marrow are wanting, ganglia and nerves supply their place. If muscles are made to contract after the nerves are removed, it is only as long as the nervous influence is inherent in them ; even after all the blood is washed out of them the same will take place for a given time. " The vitality of the blood, its formation and trans- formation into the solids and fluids of the body, the capability seemingly inherent in solids and fluids of certain interchanges which they undergo by means of their reciprocal aflSnities and agencies, still preserving their respective homogeneity; and the resistance which collectively they are enabled to maintain against injury and disease, as well as the power of repair, are referable to their nervous endowment." — Travers on Inflammation, &c., p. 17. " The involuntary functions are closely connected with the encephalon and spinal chord, for the sudden destruction of these parts, or of a certain extent of them, puts a stop to the circulation;"* and is this not a full stop ? It Is not the question of one part of the nei"vous system or one system of nerves, but of nervous struc- ture ; and there is no instance on record of any abortion, where physical structure in the shape of * Dr Elliotsoii. BRAIN AND NERVES. 15 brain, nerve, or ganglion, is wholly absent. The most monstrous formation claims this privilege ; and where brain and spinal chord are wanting, the ganglionic system has been found in excess of development. " The heart never exists without its ganglion, so that the cardiac ganglion, as the heart is the first organ that comes into action, is the commencement of the nervous system."* Is not its first action dependent upon this little ganglion? and can more be requisite to prove the supremacy of the nervous system over the vital func- tions ? In reply to the assertion that " vegetables absorb, assimilate, circulate, secrete, and, in many instances, contract on the application of stimuli, and yet are not supposed to possess nerves," it has been found that strong electric shocks passed through the pith of the trunk destroy the tree. Although it may not be proved that vitality and nervous influence are the same, yet we find them so intimately blended together in all the functions, that it is difficult to separate them. We find, moreover, that injury to the nervous system is followed by more disastrous effects than to any or all the other parts collectively. The division of a nerve is the annihilation of mus- cular power. If a sedative be applied to it, the muscle becomes inert. The point of the stiletto dividing the spinal marrow above the phrenic nerves, fells the ox to the ground. * Dr Elliotson. 16 RESPIRATIOX. — ANIMAL HEAT. If the nervous power be abstracted from the blood it loses its vitality. " By the instrumentality of the nerves, the brain makes the voluntary muscles con- tract, influences the functions of every other part when under the operation of the different passions, and re- ceives impressions made upon every other part." So much in a general sense. We shall now treat of its influence more specially, but only as far as great leadinof and strikins facts are concerned. RESPIRATIOX.— ANIMAL HEAT. The human offspring, launched into the world wholly unprovided by nature against the physical ills which surround it, seeming, as has been said of old, plusqnam novercd qiiam matre nata, is made sensible of the change in its existence by a feeling of distress, which is convertible into a voluntary instinctive effort to breathe. It struggles itself into life. This primary effort by which oi'gans hitherto passive are called upon to play an active part, and one the most essential to its future existence, is allowed by modem physiologists to be the exercise of the volun- tary muscles ; and, as the will is conveyed to these through the agency of the nerves, it must be allowed that this power is the principal instrument in the orchestra of the drama of life. The blood, which nourished it in its dependent state, is no longer meet for the same purpose when the off- spring assumes a substantive existence, nay, it is prejudicial to it, and were it not changed in its chemi- RESPIRATION. — ANIMAL HEAT. 17 cal characters and properties by passing through the lungs, which is effected by the first inspiration, the very strua-^les it makes to breathe would render it at once a caput mortuum. The uses of respiration are the purifaction of this fluid, and the generation of animal heat. The first is efiected by submitting it to the influence of atmo- spheric air, which it receives throughout the immense surface of the expanded lungs, and this process is assumed to be wholly chemical. "We recognize the nervous power in this voluntary action of throwing the blood into the chemical laboratory. In the gene- ration of animal heat we shall find the same power possessing a still greater influence. As regards animal temperature, it must be considered in a double sense, viz. in the chemical acceptation of the term, or caloric, whether free or latent, and in the nervous sense, or the sensation of heat. The standard human temperatm-e is 94° Fahrenheit. It is susceptible of an elevation of 14° under diseased action. Dr Elliotson states that he has found it as high as 107° under the tongue in inflammatory fevers, and in tetanus 110''. In some affections, on the con- trary, there is a great reduction of temperature from the natm'al standard. In the Asiatic cholera the ther- mometer placed in the mouth did not indicate more than from 77° to 79° Fahrenheit, and the same is the averao^e in children affected with the blue disease. In many other affections, the sensation of cold is much greater than would be waiTanted by the thermome- tric indication of the abstraction of the natural tem- perature. Under natural circumstances, some parts 18 RESPiRATiox. — axi:mal heat. of the body are always warmer than others. AVhat are the principal agents employed in the generation of animal heat, and Vvhat the superintendent power ? In a chemical point of view, the whole phenomenon is resolvable into the different capacities with which certain forms of matter are endowed for holding calo- ric ; or it is attributed to a process of combustion continually going on in the extreme vessels by which the carbon of the blood is, by its union with oxygen, converted into carbonic acid gas, and, in this process, heat is evolved, as it is in the ordinary process of the combustion of charcoal, out of the body. A host of evidence proves, that however this process may be eftected, yet, as far as regards animal tempe- rature being maintained in the system, it is the bi'ain which has the supremacy in the direction of the func- tion ; for, were it merely chemical, the same conjunc- tion of matters should produce the same effects, which does not prove to be the case. Sir B. Brodie's experiments afford us evidence, that although the chemical part of the process may be performed under artificial respiration, yet that the animal heat declined rapidly in all cases where the brain had been removed, and this is in perfect harmony with the powers of resist- ing heat and cold, which the nervous system possesses in an extraordinary degree. Dr Elliotson says, that these experiments prove nothing, and insists upon the process being purely chemical. Still, the same author adds, " This does not prevent animal temperature from deserving the epithet vital, because it is re- gulated by the vital laws of the system, although through the instrumentality of chemical changes." It RESPIRATION. — ANIMAL HEAT. 10 depends upon respiration, — true, but upon that respira- tion only which is performed under the direction of the nervous power. It is lost under the artificial method. Between heat as the result of chemical action, and the sensation of heat as a nervous impression, there is a striking difference. It is allowed by those who support the mechanical chemical doctrines, that it is very difficult to account for the difference of tempe- rature in parts of the same animal. The dog's nose puzzles them, as does the circumstance of the sensa- tion of heat in certain diseases, bearing no relation to the real measurable difference of temperature. A range of from 10° to 14' is about the maximum of increase. Now, if we dip one finger in a basin of water at 96°, and the other at the same moment in one of 110°, the difference will be perceptible, but in a triflino- dea'ree. Under other circumstances, this ele- vation, nay, half of it, will be as red-hot ii'on to the part affected. This can only be accounted for by nervous derangement. "What comparison can be made be- tween the sensation of heat in the gouty limb and the sound one, placed, as far as temperature is concerned, in the same cii'cumstances. The latter would hardly be conscious of the addition which causes the excru- ciating pain of this disease, and is a direct proof of offence in the nerves of the part affected, of which this increased temperature is a consequence not a cause. There is a wide difference between heat in its free state and the sensation of heat. In fiirther considering the subject of elevation of temperature in the surrounding medium, and the constancy of that in the animal, we nmst recognize the influence of tliat 20 RESPIRATION. ANIMAL HEAT. vital power which watches and presides over the ma- chine which it animates. Thus we find the body capable of resisting a tempe- rature sufficient to decompose dead matter. Animals, as well as man, have been exposed to a degree of heat exceeding that of boiling water, and without injury ; Avhen, at the same time, a thermometer placed under the tongue, has indicated an elevation of a few degrees only above the natural standard. This power of resistance is but of short duration, for the nervous influence is exhausted by so extraordinary a demand. Chemical agents come into play, and matter is resolved into lifeless form. As regards cold, the same law prevails, the limits are the same. However great the power may be of resisting it, as soon as the nervous energy is exhausted, the system is subject to injury. I have witnessed the effects of cold too long en- dured upon the little postillions, Avho are barbarously exposed to it in the winter season at St Petersburg. The lads bear it for a time, as they sit on their horses, clapping their hands, and singing to keep up their courage ; but this fiiils them by degrees, and, finally benumbed, they fall from their saddles in a state of torpor which nothing but rolling them in the snow will overcome. There is seldom a fete given at St Petersburg, in the extreme cold weather, that occur- rences of this sort are not recorded. In very cold nights the sentries are frequently frozen to death, if not relieved at short intervals. As long as nervous excitement can be kept up, the resistance of cold is very great. General Piroffsky EESPIRATIOX. — ANIMAL HEAT, 21 informed me, that in tlie expedition to Kliiva, not- withstanding the intenseness of the cold, the soklicrs marched along, singing, with the breasts of their coats open, but only as long as they were flushed with the hopes of success. Where there is nothing to excite, and where exposure to cold takes place under tlie common routine of parade, its depressing effects are lamentably felt by those long exposed to it. In the time of the Grand Duke Constantine, a regiment of horse was marched from Strelna to St Petersburg, a distance of twelve miles and upwards. He marched at their head at a foot pace all the way. Pie had well wadded himself, and smeared his face over with oil. It was the gratification of a whim to expose the soldiers to a great degree of cold. They arrived at the square before the palace, and were dismissed to their barracks. The following day one-third of the resfi- ment was in the hospital, attacked by nervous fever, of which many died. There was no stimulus of neces- sity in this case, but the moral feeling aggravated the physical suffering. The soldier is much better taken care of now-a-days in Russia, Cerebral affections are a consequence of reaction Avhen the nervous system has been too much exhausted. I have mentioned else- where the case of the bishop of Nicolai, who died in a few hours of brain fever from exposing himself to severe cold during the performance of a religious rite. AVe find that, when the nerves whicli supply a limb have been di\ided, the temperature falls, and that it is again raised by galvanic power. Mr Earle found a paralyzed limb to indicate only 70°, the sound one 9^". By electricity the former ^vas raised to 77", 22 EESPIRATIOX. — ANIMAL HEAT. Berzelius adopts the opinion, that the nervous influ- ence not merely in connexion with respiration, but in other orf^anic processes, contributes to the production of animal heat ; and IMiiller coincides in this idea, founded upon the spontaneous generation of heat under the influence of passion, — the sudden rush of heat to the face, which is not a mere sensation, — the increase of Avarmth to the body amounting to perspi- ration. On the contrary, the equally rapid diminution of temperature. Tlie coming all over in a cold siceat is an expression of the effects of sudden fear; and sudden sensations of cold are not uncommon conse- quences of depressing moral emotions. The power of maintaining an equable temperature is in a direct ratio with the health of the individual. It is greatest in youth, and decreases wuth age. Ner- vous people are peculiarly subject to chilly feelings, and we know how much more the body is liable to catch cold when exposed to drafts or currents after some degree of fatigue. It lias been a very great mistake in the treatment of the insane to suppose them less susceptible of diminished temperature than those in a sound mind. It is just the reverse, those who are in this lamentable situation requiring more warmth than under ordinary circumstances. The whole of the evidence which can be brought to bear on this subject will tend to place this vital function under the most especial direction of the nervous in- fluence ; and this is not a little corroborated by the circumstance of that which approaches nearest to it in power, viz. Galvanism, being capable of exciting heat in a paralyzed limb. THE BLOOD. 23 PART 11. THE BLOOD. The name of John Hunter is as intimately associ- ated with the properties and functions of the blood, as that of Harvey with the discovery of its circidation. The great lawgiver of IMount Sinai did not estimate it so highly, when, denominating it the " life thereof," he poured it out in sacrifice, as do some modern physiologists, who sacrifice all to it. In following the footsteps of an idolized predecessor, we sometimes make a stride too far, and inadvertently place ourselves in the foreground ; we take the lead ourselves, and pursue the shadows of objects which have been of our own creation. It was precisely this which led the late Mr Aber- nethy astray, in the tribute he w^ished to pay to the talents and merits of this great physiologist. So anxious was he to do all justice to his doctrines, and render to him all that was his due, that he finally gave to him more than his leg-atees were willino- to claim. When Mr Abernethy broached the opinion that life and electricity were synonymous, he did not take the merit of the discovery to himself, but sanctioned it by the name of John Hunter ; whilst those who did not adopt these opinions, protested that, in all the works of that physiologist, nothing could be found to sub- 24 THE BLOOD. stantiate the idea that John Hunter had ever dreamt of the like in all his reveries : — not a word of shoulder knots was there in the testament. Now, surely it is not doing justice to anv author to treat him in this wise; and, attached as we are to the memory of that great physiologist, we do not consider that it is honoured by the modem school of medical Puseyites, who, under the sanction of his name, preach the doctrinal exclusiveness of" flesh and blood," and sink the more refined influence of the nervous poAver. John Hunter insisted upon the vitality of the blood, and his opinions upon this subject may be considered as established and recognized facts ; and, since his day, the blood and vital fluid have become synonymous terms ; but he nowhere asserted that it possessed more vitality than the other component parts of the system, nay, he only laboured to prove that it possessed as much. He based his theory upon the following rational o-rounds : — If all living structures are alloAved to be formed from the blood, at what precise period in their transition from the fluid to the solid state is this vitality transmitted to them ? Is it not rational to suppose that this principle shoidd be as inherent in the forming as in the formed stiaicture ? This is all that John Hunter maintained, and there are few who do not subscribe to the truth of his opinions upon this matter. But admitting the fact, recognizing the vitality of the blood, as far as the term can be under- stood, still the question is to be mooted as to the source of its vitality. The processes of digestion and assimilation supply THE BLOOD. 25 this fluid to the system, and it may be abstracted almost to its last drop, and again be renewed by these fmictions ; and as we find that these are under the con- trol of the nervous power, and, if it be not in full vigour, they are performed imperfectly, so we may ask at what period the chyle becomes vital in its admixture with the blood, from which, if it receive, to it also doth it impart, vitality. All the arguments brought forward by the most zealous partizansofthelTunterian doctrines in favour ot the blood's vitality, do not attempt to prove more than that it enjoys this with other structures, neither more nor less in degi'ee, nor of a more subtile or intellectual kind. If John Hunter succeeded in establishing the vi- tality of the blood, as a moveable fluid, the changes which take place when at rest, whether confined in its vessels or removed from them, add strength to this opinion — we allude to its coagulation. This is attri- buted to the stimulus of death by Hunter. Mr Travers has styled it the last act of its life, in his neat and classical Essay on Inflammation and the healing process. The mechanical and chemical arguments wholly fail in attempting to account for this singular process. It must be referred to the influence of that great efl:brt which the fluid still makes to move in its usual current ; but, baflBed in its attempt, it is thrown into an eddy, and losing by degrees its nervous power, not without leaving marks of the death-like struggle, stiffening as it cools, it yields to the superior influence of its chemical antagonist. It has often reminded us of that passage in Mon»' C 2Q THE BLOOD. taigne, wiiere he describes a combat between two warriors, and the struggles -svliich the vanquished raade to the last : — " Jamais homme n'a vecu si long-temps dans la mort, jamais homme n'a tombe si debout." Now, as regards this phenomenon of coagulation, it is as much proved to be vital bj negative as by posi- tive evidence, and vitality cannot be implied inde- pendently of nervous influence ; for when this death- struonfle — this last Ions; fiickerinor flame is not sus- tained by nervous influence, which still clings to it for a time, although removed from its channels, as the heart pulsates for a while when removed from the body ; when this influence is too suddenly withdrawn, as when the nervous power is crushed by the thunder- bolt, or exhausted and spent, as in the hunted hare, then the testamentary evidence of the last living act is not apparent ; for, in such instances, coagulation does not take place ; — the blood is found in a fluid state. It will be in harmony with the subject before us to inquire how" much of this fluid may be abstracted without causing death. We shall first speak of hemorrhagy from rupture of blood-vessels, and shall find, at the tlu'cshold of our inquiry, that nature often intervenes in arresting it, and this she does through the agency of the nervous system. The heart, de- prived of its stimulus ceases to pulsate with suflScient force to propel the blood as before, and the ruptured vessel is closed by the coagulated plug. This is efl^ected by the loss of nervous power, not total but partial, causing coagulation, which is the termination THE BLOOD. 27 of a vital process, where exhaustion of nervous power has not been too rapid. The swoon and the fainting fit are the agents by which the life apparently lost is in reality preserved. Now, this singular phenomenon, which preserves the life of the ex-sanguine, is accom- plished through the nerves negatively. It is by robbing them of theu' power that this effect is pro- duced. Deprived of their food, they fall into a state of exhaustion, which very state does, by its consequences, prevent any farther waste of nutriment. This swooning may be accomplished by means of a more subtile kind. Joy, grief, fear, the passions and affections of the mind, may so overcome the nervous power as to jiroduce it. In these cases, the blood is not the controlling but the controlled power. The same may be effected by direct injury to a nerve; any sudden pain may, nay, the treading on a corn shall be sufficient to, prostrate the strongest, and rob the body for the time of all semblance of life. In the state of swoon the blood acts but a passive part ; if it coagulate in the divided trunk, it does so from its being in a state of rest, and perhaps some atmospheric influence may assist ; its propelling power is withdrawn ; and, when this is restored by the re- newal of muscular action, it flows again at a rate commensurate with the force it feels. It is by direct application to the nerves that we endeavour to rouse the fainting man into life ; we dash cold water in his face, on the sentient extremities of a large expansion of nerves, and these outposts transmit the impression to the brain ; reaction takes place, the respiratory muscles arc called into play, the chest expands, the 28 THE BLOOD. blood passes through, the pendulum moves agam, and the life of the swooner is restored in much the same way as it is called into action in the new born child. Let us give to the blood its due in restoring the heart's action. In its retreat from the brain it is choked up in the citadel, congested in the extremities. It cannot overcome the laws of gravity, having lost its vis a tergo ; and, as the difficulty is increased by the erect, we seek relief mechanically by placing the patient in the recumbent posture, that the blood may flow more freely in a horizontal line. This disposition to swooning in an erect position, from robbing the brain of its usual quantity of blood, is illustrated satis- factorily in the following case : — " A lady, past the middle age, was so subject to faint when in the erect posture, that slie was, although otherwise in good health, confined to her bed and sofa; as soon as she attempted to rise she felt faint or even swooned. The cause of this phenomenon for a long time baffled the skill of her medical attendant, till, by some accident, he discovered that she had immensely varicose veins in both legs ; and in the erect posture these became reservoirs for the blood, which accumulated too much in them to be propelled forward ; hence the balance of the circulation was deranged, and the brain, robbed of its usual quantity, manifested symptoms of its Aveakness. By the application of proper bandages, which supported the vessels in an erect posture, this distressing aifection was overcome." * When we consider the importance of this fluid, so n^cessai'y to life that it has been identified with life * Dr Wilson, THE BLOOD. 29 itself, wc arc surprised at the enoraioiis loss which the system is enabled to support. We look ^vith horror on the bleeding soldier and parturient woman drained to the last drop, pale, ex-sanguine, pulseless, motionless, cold to the feel, bedewed with the insensible perspiration converted into sweat, and yet a spark remains. Plow is this ember to be kept alive ? How gently fan the flame or replenish the fuel without extinguishing the spark. Drained of its vital stimulus, where are we to look for a substitute ? Is it our object to replenish it by direct transfusion, about which so much has been said and so little done ? We resort to the nervous system, that it may assist the heart to continue irs action in its debilitated condition, until time be aftbrded to convert other materials into new blood, ^^"e act upon the nerves by applying stimulants to the stomach., which become thus diffused throughout the system, and M'hat remains of the vital fluid is ])ropelled, and its quantity restored at each pulsation. Here we see the mutual dependency of the systems on each other's efforts. The brain and nerves, de- ]>rived of their natural stimulus, become exhausted, and unable to carry on their functions ; but it is only by rousing them that the fluid can be supplied wdiich is necessary to this purpose. This is the peculiarity of the nervous system, — it cannot act without the food which it must itself supply. In speaking of the quantity of blood in the system, great discrepancies exist in the opinions of physiolo- gists upon this subject, — a difference allowing of a range from eight to thirty pounds. Sir Astley 30 THE BLOOD. Cooper estimated it at an ounce per pound of solid. Now, seventy ounces of blood have been taken from the arm, one-fourth of the whole of the vital fluid, Avithout causing complete exhaustion, and the system has rallied again under such a loss, Avhich, if the nervous energy be not too much impaired, will be in time replenished.* It is impossible to calculate how much blood has been lost by parturient women, or how much in cases of menorrhagia, where it streams away daily for weeks together, it is our object merely to insist upon the difference with which the system supports the abstrac- tion of these two powers. We cannot measure or weigh imponderable matter, so that we can have no idea of quantity as regards the nervous or electric fluids ; but we can judge of injury done to that form of matter with Avhich their power is identified ; and we know that if the chord through which it passes or vibrates be offended, the whole system may be thrown into convulsions. The blood may be abstracted to more than a fourth its quantity without making any very marked difference in the system for the time being. The man of Herculean strength shall bare his arm, and lose \\h\i impunity a fourth of the vital fluid. To some it is a pleasurable sensation ; but if, in the operation, some nervous twig be mutilated, such shall be the shock to the sensorium, that it shall fail in its functions, and the colossus shall fall pros- trate on the earth. * Dr Parry estimated it at 20 lb. JVofe. — A woman died of hemorr- hagy, losing "26 lb. From a full blooded young woman, who was beheaded, 25 lb. were collected. — U^risieni. THE BLOOD. 31 If we pass ill review the eiFects of injuries upon tlie nerves from the prick of a thorn, to those resuhing fi'om concussion and compression, — if we regard the moral and physical consequences from the slightest to the greatest injury, we must acknowledge how much more importance has been assigned to the nervous system by nature than to any other components of the living mass ; over the blood it has a decided supe- riority. ^^'e can abstract a very large portion of the latter from the system, — we can exchange it by trans- fusion, and still life goes on ; but all attempts to supply nervous power beyond a momentary galvanic shock, which gives motion to the muscles, but cannot propel tiie dead clot or restore its vitality, have hitherto proved fruitless. Here we see, however, the mutual dependencies of the systems on each other ; the fibre may be made to contract without the assistance of the blood ; for, when wholly deprived of this fluid, contraction will take place from irritation of nerve. The butchers' shambles furnish us with proofs. The muscles of the ox may be thrown Into contraction hours after the eviscerated animal is stretched upon the hooks. The blood plays no part here ; it has flowed into another channel, but the nervous survives the sanguiferous power. In all the experiments made upon dead bodies, where muscular contraction has been pro- duced, no change producing anything like the sem- blance of life has occurred in the blood when coagu- lation has already taken place. It is the first to part with its vitality, which never can be restored ; for chemical action asserts its prerogative, — as soon as 32 THE BLOOD. the vital power yields, the chemical predominates. This death of the blood soon involves that of the muscle and of the nerve. Neither can maintain its privileges in a divided state, either physiologically or even anatomically. We cannot drain away blood from muscle, or tear filament from fibre, without compro- mising the existence of all three ; for that which can- not perform its wonted functions is, de facto, no longer the same. In losing its adjective, constituting shape, it is not cognizable in a substantive form. The mummy can- not be said to possess muscle or nerve. These are not represented by chords and strings, nor does the putrid clot in the barber's shop afford any distinct idea of that once scarlet fluid which, propelled into the muscle by nervous influence, gave beauty to the features. How is the contrast drawn between life and death in the three systems by Ovid in his Mori- bund : — " In vultu color est sine sanguine, himina nioestis Stant immota genis, nihil est in imagine vivi. Ipsa quoque interius cum duro lingua palato Congelat, et vence desistunt posse moveri, Nee flecti cervix, nee brachia reddere gostus, Nee pes ire potest." OvkVs Metamorphoses, MUSCULAR 3IOTIOX. — CIKCULATION, PART III. Muscular ^Motion — Circulation — Nutrition — Secretion. MUSCULAR MOTIOX.— CIRCULATION. Le Gallois confesses, that in his experiments to ascertain the influence of the brain upon the circulat- ing system, he made a horrible sacrifice of animal life. Dr Wilson Phillip, not satisfied -with Le Gallois's views, performed more experiments of the same nature, and perhaps a score of experimental physiologists have pursued the same system of torture to prove, after all their trouble, that the heart has an action independent of the nerves, which, however, influence its movements under oi'dinary circumstances. It is, as has been justly observed, the business and work of a life to know what is true upon any physiological subject. Doubts, contradictions, and discrepancies, no where exist to a greater extent than on the subject of circulation. When Harvc}* laid down the rails, he little dreamt of the squabbles which would exist concerninti; the nature and mode of starting the loco- motive. It will be sufficient to quote one paragraph from Dr KUiotson to satisfy us on the point of nervous co-operation in influencing the action of the heart : — " The great influence of the nerves over the heart is demonstrated by the size of the cardiac nerves, ami by tlic great sympathy between the heart and most di MUSCULAR MOTION. — CIKCULATION. functions, however dlfFerent. A convincing proof of this is the momentary sympathy of the heart during most perfect health with all the passions." He further adds, " Since a supply of nerves and blood is requisite to the action of the voluntary muscles, it has been inquired whether these, both or either, are requisite to the heart also." In alluding to the influence of respiration on the heart's action, we get immediately into a field of con- troversy. Thus, when I was in Paris, I had an opportunity of witnessing the late Sir David Barry's experiments, by Avhich he seemed to prove that the venous circulation is performed by means of pressure, and that during inspiration a vacuum is formed in the thorax by expansion, and during this time the vejious blood is propelled towards tlie heart, whereas during expiration it remains stationary or retrograde. Dr Bostock, avIio published his system of physio- logy a little posterior to these experiments, observes : — " In natural respiration there is no effect produced upon the circulation, and consequently no alteration is felt in the pulse. With respect to all experiments, this great objection exists, that respiration must always be in a forced state from the pain produced, which invalidates the proofs." MuUer adopts the same line of argument, as it is difficult to separate the simple act from the effects of the changes which it produces in the nature of the blood, and the chemical and ner- vous influence accompanying it. " Another phenomenon," says Muller, " which dis- tinguishes the heart from other muscles, is the persis- tence of its rhythmic contractions in their regular MUSCULAR MOTION. — CIRCULATION. 35 order in the difTerent cavities, even when removed from the body and emptied of its blood. This cannot be explained otherwise than by supposing the heart, under these circumstances, to retain, with its nerves, some specific nervous influence." — P. 203. This is proved to be the case by galvanism exciting the heart to contraction after its removal from the body, a statement which has been confirmed by recent experiments. Le Gallois learnt, during his prosecution of this subject, that the brain and spinal marrow had great influence over the heart's action, and that although this might be continued for a certain time after their removal, it was much feebler, nor was circulation per- fectly performed, for Nasse measured the height of a stream of blood flowing from a divided artery, and then by injuring the spinal chord, found it decrease in altitude in direct ratio with the injury. Harvey declared the heart's action sufficient for the circulation ; and notwithstanding the many assertions to the contrary, the German physiologists still adhere to this o[)inion, and maintain that the circulation in the capillaries is wholly dependent on the heart's action, as the most feeble contractions of the heart in a frog, nuich exhausted, are perceptible in the capil- laries. Dr Bostock considers the arteries to possess nniscularity, but asserts that contractility can be eft'ected without the intervention of nerves. This applies only to the involuntary muscles, which are not excited by galvanizing the nerves which go to them. iJr li. couaitlers the cause of contraction as a pro})erty aai fjeneris, and not accounted fur by any 3G MUSCULAR MOTION. — CIRCULATION. liypothesis hitherto known. Others refer contraction entirely to the nerves of both kinds of muscle. As far as is necessary for our purpose, it is suffi- ciently evident tliat the influence of the nervous system is very considerable in promoting and main- taining the circulation of the blood. Its self-propelling power is satisfactorily disproved by Midler. All the apparent motions and flickerings observed in the ca- pillaries are due to mechanical causes acting upon the sides of the vessels, or by the attraction exerted on the blood by the solid walls of the vessels. Dr Elliotson substitutes the term myotility for the irritability of Haller. It is necessary to consider here the influence of the nerves in producing muscular contraction. " Every part of the muscles is amply supplied \^'ith blood and nervous threads. The latter appear to deliquesce into an invisible pulp, and unite intimately with the muscukr fibres." * This is most important to those who can trace the effects of the blood, under jiecidiar circumstances, to this cause, without ascribing them to ofl'ence in the blood itself. Any stimulus applied to a muscle, or to its nerves, excites contraction ; but if this deliquescence of nerve through the muscidar fibre maintains, it must, in ail cases, be an application of stimulus to the nerves. Blood and nerve, then, are inseparable from muscle in its normal state ; and sensibility and contractility are due to their influence. The two phenomena of sensation and contraction are not seated in the same nervous fibrils, as stated * Elliotson. ]MUSCULAK MOTIOX. — CIRCULATION. 37 in the consideration of sympathy. The property of contracting is retained by a muscle for some time after death by the apphcation of stimulus, chemical or mechanical. The muscles of the flank of an ox are seen to play in this way after it has been eviscerated and stretched out upon the hooks ; and if the part be touched with the point of a knife, strong contractions are produced in the muscle. I have often witnessed this in my younger days, and amused myself with the experiment. It is proved that this contractile power is diminished where animals have been destroyed by immersion in carbonic acid gas, or by poisons injected into the blood. This involves the Cj[uestion, Whether it is the blood, as Dr Stevens maintains, which is killed by the poison, or the nervous delicjuescence with which the blood comes in contact in the muscle. " The poison itself is the remote, but the vitiated state of the blood produced by the poison, is the immediate, cause of fever, as certain as that narcotic poisons, when injected into the veins, can instantly destroy the vitality of the blood, and cause death, without producing or leaving the slightest trace in any of the solids."* With respect to the first position, that the vitality of the blood is destroyed, there can be no objection, l)ecause the nervous influence of the blood may be destroyed in the fluid simultaneously with the nervous deliquescence in the muscle, into which the blood penetrates. Although our means of ascertaining the injury done * Stevens on the Blood. 38 MUSCULAR MOTION. — CIRCULATIOX. to the solids be not so complete as to demonstrate any lesion, still we judge by function that such must be the case, for we find that narcotics applied directly to the muscles destroy their irritability, and, if applied to the nerves, deprive them at the point acted upon of the property of exciting muscles to conti'action ; and this is caused to a greater degree by local applica- tion of poison in a concentrated state than when introduced into the veins. The experiment of intro- ducing strychnine into the veins, and dividing the nerve of an isolated muscle, when this muscle alone shall be quiescent, is conclusive that the solids are affected by poisons, that the injury to the nerves is the cause of contraction, and that where sudden death is produced, it is not the vitality of the blood alone which is destroyed, but of the flesh, simultane- ously. The poison of the rattlesnake introduced into the veins is instantaneous death, whereas poisons taken Into the stomach are inert, according to Dr Stevens' ideas. This but proves what nobody disputes, that there is no medium of diffusion equal to the circidating fluid ; but whether it be this primarily that is so aflected, is more than doubtful. A drop of highly concentrated prussic acid placed upon the tongue is as instantaneous in its effects as the bite of the rattlesnake, and much more so ; but this is not caused through the medium of the circulation, but by immediately getting to the brain by volatilization ; and there is no death so instantaneous from the injection of poisons into the veins, as that the brain shall not, by medium of the circulation, be affected by the injury. MUSCULAR MOTION. — CIRCULATION. 39 The presence of blood, and of decarbonized arterial blood, is necessary to the healthy contraction of muscles, as the little muscular power of those affected with the blue disease proves ; but muscular contractility does take place where all the blood has been washed out, and the heart removed. — P. 896, Mailers Physiology. Dr EUiotson combats the opinion that muscular contractility is due to the nervous system ; and still he allows that so much is dependent upon it, that but a fraction is wanting to make it a whole, lie does not ascribe it to the blood, however, but says that " the power of contraction is their own," Avhich coincides with Dr Bostock's ideas. That detached muscles contract under the applica- tion of all stimuli would only argue that nervous ]!Ower is still inherent in them. Where the trunk of the nerve has been divided which supplies them, this contraction is found not to take place. An experiment of Sir Benjamin Brodie's tends to prove that the trunk of a nerve when separated from the brain and spinal chord, retained for a considerable time its faculty of excitin": the muscles to contraction when irritated. ]Muller, who places Sir Charles Bell's experiments on a par with Harvey's, adopts a kind of middle course, but still comes to the nerves for assistance. " Irritation of the gustatory branch of the fifth excites no contrac- tion of the lingual muscles, nor does irritation of the infra-orbital nerve any motion of the nostrils and lips of animals. The fact proves that mere nervous influ- ence, as a general property, does not act as a stimulus for muscular contractions in the manner of other stimuli, but that for the excitement of muscles to contraction, 40 MUSCULAR AMOTION.— CIRCULATION". a specific action of a special class of nerves is neces- sary. The extinction of the mnsculur irritabiUty, after a time, when the nerves have been paralyzed by division, and their accidental union prevented, is the most con- clusive argument in favour of the opinion, that for excitement of muscular contractions, the integrity of the nerves ramifying in the muscles is necessary, and that the muscles themselves are not susceptible of the direct action of stimuli Yet it is evident that the contractility must be a property of muscles themselves, and that the nerves cannot, even during life, impart to them a power which they do not possess themselves. But the manifestation of the contractile property of muscles pre-.supposes a concur- rent action of the nerves." — P. 900. Of the influence of the mind upon the voluntary muscles, sufficient will be found under the head of Mesmerism. As to the iuAoluntary, it is difficult to say where one usurps the functions of the other. Dr Elliotson relates many interesting cases of the mind controlling the supposed involuntary movements. — P. 484. As reffards the share the nervous system has in their functions, it is, from whatever sense it may be derived, as great as in the voluntary.* Colonel Townsend's case is Avell known. The possibility of self-destruction by holding in the breath, was, I re- * The application of a stimulus to the nerve before it has reached the muscle, has the same effect as irritating it in the muscle itself. This i^; a fact well known with regard to the cerebro spinal nerves, but that it is true of the organic or sympathetic nerves also, has been more recently discovered.— iVii7tr, p. t'UO. NUTRITIOX.— SECKETIOX. 41 collect, positively denied by Sir Astley Cooper. The following proves the contrary if it can be depended upon : — A robber, named Coma, when taken before the consul Pupilius, is said, by Valerius Maximus, to have so destroyed himself. Let others, says the his- torian, sharpen the sword, mix the poison, &c., " nihil liorinn Coma, sed, intra pectus inclusa anima, finem sui reperit." — Lib. ix. cap. xii., extern. 1. — Elliotson's Phi/siologi/) p. 492. NUTRITION.— SECRETION. The influence of the nervous system upon the pro- cesses of digestion and assimilation, presents us with many striking facts of a moral and physical kind. It has its usual share of labour in this department of organic life. Dr AVilson Philip's experiments bring us directly to the point. When the eighth pair of nerves is divided digestion ceases, and by the application of galvanism to the divided extremities of the nerves, it is completely restored. Thus a rabbit is enabled to digest [)arsley by this substitute for nervous power. These experiments have been confirmed by others, so that the triumph of the nerves over this function is complete in its physical demonstration.* This applies equally, whatever may be considered to be the means (jf performing the function. Dr Bostock argues the assistance of chemical fermentation, and does not * Dr Carpenter cavils at this conclusion of Dr Wilson, but 1 do n<jt think upon good grounds. 42 NUTRITION. — SECRETION. consider the gastric juice sufficient of itself; and Dr Prout reduces it into two operations : reduction of the food into a homogeneous pulp, and secondly, conver- sion of the staminal principles into substances similar to those which enter the blood ;* still the controlling power is the nervous. Since the process of digestion has been studied in the living man, it will be unne- cessary to make more experiments on animals, we must refer to those of Dr Beaumont on the Canadian. These experiments, so interesting in themselves, and so rich in their application to practical pathology, prove that febrile commotion, as well as sudden emotions of mind, occasion an almost immediate change in the vascular appearance and condition of the inner surface of the stomach, and also in the secretion and sensible qualities of the gastric liquor. AVhatever disturbed the nervous system of Martin also disturbed the villous coat of the stomach and its secretions. When St ]Martin suffered from any febrile attack, with a quick pulse and dry tongue, the secretion of the gastric liquor was suspended, and any food which was swallowed in such a condition of stomach, re- mained undigested for upwards of twenty-four hours, and consequently, naturally aggravated the general symptoms of disease.! Digestion is always imperfect in weak and nervous people ; but the process, in its most healthy state, will be suspended by moral emotion, which will also cause vomiting. * Both these processes are chemical, and are styled primary and secondary assimilation, f Sir A. Crichton, p. 121. NUTRITION. — SECRETION. 43 The subject of secretion embraces a large portion of the science of physiology, and ofters much room for speculation. We have no fear of finding that the nervous system will lose any ground, as regards its superintendent powers over this function, as over all the others. It is here, however, that the blood assumes all its dignity. A combination of the elements of fluids producing a new arrangement of their parts, and the formation of a compound differing in its nature and properties from the mass out of which it is com- posed, may be said to form the process of secretion. This mass is the blood, which supplies all the material for all the difterent fluids AN'hich are eliminated from it. The product of sugar, Avhich is very abundant in disease, proves that, as healthy blood contains no particle itself of this matter, it can only be by resolution into its elements that this substance is produced. In tlie process of digestion the principal agent is a secreted fluid, the gastric juice. This formation is suspended by lesion of nerve, and restored by the nerve's substitute, galvanism ; so that, upon the outset of inquiry, Ave recognize the ruling power. In the processes to wliich it is subjected in its resolution into elements, the blood must necessarily part with its vitality ; but as we find some of its products endowed with this principle to the same extent as itself in its normal state, Ave must look for this ncAV endo\A'ment somewhere, and we can only find it regenerated by the nervous system. The secretions bear no proportion to their organs as regards mass, and Haller maintained that no [)ar- ticular structure Avas necessary for any specific secre- 44 NUTRITIOX. — SECriETIOX. tion, but that any structure might, under certain circumstances, usurp the functions of another. This, however, is not strictly correct ; the suspension of a natural secretion is not remedied by another organ usurping the function of its associate, but by absorption into the blood Avhere the natural exit is impeded, and the absorbed fluid is discharged by exudation. The vicarious secretions are never complete. Dr Wilson has called the attention of the profession to this sub- ject, as regards renal affections, but we shall speak of this hereafter. If the ureters be tied, or the nerves supplying the kidneys be paralysed, the effects are manifested on the brain. The blood is no doubt the ofl'ending agent ; for, although the experiments of Darwin, instituted to discover a high road between the stomach and the bladder, which led him to tie the ureters, were produc- tive of effusion into the ventricles, yet in the cases of renal affection mentioned by Dr Wilson, apoplexy was produced without any physical lesion, or any effusion. The offence was sufficient, of blood not fit for the purposes of life, when not deprived of what the urine takes away from it. One secretion may, however, be supplied by an- other, so as to prevent detriment of life ; if the urine is very scanty, the perspiration has a strong urinous smell. Of the suspension of urine in cholera, I have ventured the opinion that the serous evacuations compensate for it, and that there is no disorganization of the kidney. — Observations on Cholera Morbus. St Petersburg, 1832. Between the skiu and the kidney there seems to be a mutual understanding; where tlie XUTRITIOX. — SECRETION. 45 function of one is suspended, the other is constantly increased in healthy circumstances. The disease Ischuria Reralis presupposed a paralysis of the nerves of the kidneys; direct experiments of destroying the renal nerves, as performed by MuUer and Peipers, prove the fact. — P. 516, Miiller''s Physiology. If we apply to the influence of mental emotions on the secretions, we shall find that there is not a secre- tion or excretion that is not changed in quantity and quality by moral causes. The Saliva. The Gastric Juice. The Bile. The Milk. The Fat. The Tears. The Perspiration. The Urine. Menstrual Fluid. These all, and severally, are influenced by nervous impressions. Saliva. — Whose mouth has not watered " at the savoury teal either before his eyes or from recollection? "Whose mouth has not suddenly been parched by unwelcome news? Is not the rabid state due to nervous influence on this secretion, of which we have furnished an example in the case of hydrophobia?"* The Gastric Juice loses its solvent power, and is suspended by moral emotions. 77ie Bile. — " Difficile bile tumet jecur," says * It is said tliat inoculation of the blood of a rabid animal produces this disease in others. — Ilerhrig. 46 NUTRITION. — SECRETION. Horace. It is well known that this secretion is much influenced by the passions. A fit of bile is a common expression for anger, producing diarrhoea and bilious evacuations. Jaundice is sometimes produced sud- denly by a fit of passion. " Segur relates that when Murat, in his retreat from Eussia, was informed of the conspiracy which had taken place at Naples, he became jaundiced suddenly from head to foot." llie Milk. — The rush of milk to the human mother's breast, and the sight of the foal distending that of the mare, are suflficient proofs of moral emotion upon this secretion. A fit of passion so deranges it that it is not fit for the child. The Fat. — This secretion is decidedly influenced by moral causes as well as physical. It is generally the inheritance of indolence, and Swift affords us a very singular instance of the accumulation of this secretion upon losing his mental powers. He was, as FalstafF would have said, as thin as a shotten herring, till he became insane, when he grew as fat as the knight himself. Parts, wdiicli lose their powers, and which, in a normal state, possess no vestige of adeps, accumulate it, as it has been found in the scrotum of those who have lost all virile power. That cheerful people are, for the most part, more disposed to obesity than the morose and fretful, is generally admitted. Washington Irving draws the parallel between the two governors of Ncav York. Walter the doubter sat for sixteen hours in his chair smoking and sleeping, till he grew too big for it; whereas William the Testy, from his turbulent and NUTRITIOX. — SECIlETIOlSr. 47 fidgetty disposition, could not be found after his decease ; he had fretted himself all a\A'ay, so that there was nothing left to bury. Some will grow fat in spite of all. Beaumarchais says, " On s'engraisse par la misere," which is perhaps a plagiarism upon FalstafFs Pshaw upon sighing and grief, they blow a man up like a bladder. Tlie Tears. — It is unnecessary to do more than mention them as instances of moral emotions affectino- the secretions. Perspiratlun. — To come all over in a cold sweat is an expression indicating the effects of fear upon this excretion, as before mentioned. Uiine. — There is, as before mentioned, a great consent between the skin and kidney, and both are influenced by fear and moral emotions. It is not our intention, in the present work, to adduce more than has hitherto been done, or swell the volume with the labours of others. A few of the most important physiological facts have been brought forward to prove the influence which the nervous system has over aU vital functions ; more than this is not contended for. There are, no doul)t, as Dr Elliot- son has observed, fancied functions of the nervous system, and the latter does not make up the whole of life ; but we do believe it to be the most important fink in the vital chain. 48 SYIVIPATHY PART IV. Sympathy — Phrenology — Mesmerism — Sleep — Dreams, SYMPATHY. When Falstaif said he knew the Prince by instinct, he solved a very difficult problem. We are often in the same predicament, without being able to extri- cate ourselves so satisfactorily as the worthy knight. Where ideas fail we can sometimes, as Mephistopheles said to the student, substitute a sonorous word ; at other times ideas are more redundant than our means of expression. John Hunter has been criticised for his " stimulus of necessity," as an unmeaning term, yet there is something very instinctively intelligible in the idea it conveys. Some physiologists have denied sympathy, but have furnished us with no better A\'ord for a multitude of effects, which cannot be otherwise explained than by the use of some conventional term. We cannot better explain the effects produced by moral causes, or the influence of one part upon an- other, between which there is no apparent connexion, than by some expression, which implies a general consent of parts, and sympathy supplies this term. SYMrATHY. 49 We have to deal with it in U\o ways, as physically and morally affecting the system. A pinch of snuff acts upon the muscles of respiration to effect a sneeze, as does the sunbeam coming suddenly upon the eye ; an affection of the liver is indicated by pain in the shoulder ; these are sympathies not exactly definable, at first sight, by communication of nerve. In the moral sense we see the effects still more strongly manifested. The cry of the distant child will cause a ru-sh of milk to the breast, and an erection of the nipple. It requires great muscular exertion to produce a yawn, and yet a whole company may be set yawning by one open mouth. Although many sympathies cannot be traced to direct ner\'ous communication of parts, still, as motion is always implied, the brain and spinal marrow, as the seat of these, must eventually come to our assist- ance in the explanation of the phenomena. In relation to the share which the nerves have, and their mode of action, INIuller's views seem lucid and explanatory. He states, that the impressions made on the sensitive fibres of nerves, which put in action the motor fibres, are not by reflex action of the two sets of fibres on each other, but by direct communication Avitli the brain and spinal chord, and by them communicated to the motor fibres. — P. 731. This helps us out of -considerable difficidty, for we find the brain or spinal chord alone concerned in sympathetic motions of the nerves. '' If a mixed nerve (motor and sensitive) be divided, and the por- tion in connexion with the brain be irritated, the D 50 SYMPATHY. animal will prove, by its movements and cries, that pain is so caused ; but the motor fibres coming oft' from the irritated branch, -will not be excited to action, as no contractions will take place in the muscles to which they are distiibuted." — P. 75G. The spinal chord is the bond of union in all cases of reflected motions, general or local, and no muscular action takes place in which this centrifugal propaga- tion of the brain to them by the motor nerves is not implied. These views, if correct, appear to simplify the subject very considerably. In all these reflected motions the sympathetic nerve can play no part, if j)rimltlve nervous fibres are incapable of communicat- ing any influence to other fibres, which merely lie in contact with them. " The old term of sensorium commune is not misapplied to the contents of tlie skull. The action of light or snutF, then, as before mentioned, is accounted for by direct communication with the brain, as any irritation of the mucous mem- brane throughout its Avhole length is capable of excit- ing all the respiratory nerves to action, and producing convulsive movements in the muscles." This part of sympathy, therefore, is disposed of and reduced to nervous communication, however eccentric the mo- tions may appear to be. This reflex action from a common centre accounts for all the spasms, contor- tions, and convulsions which are caused by irritation of a nerve, and they will be in direct ratio with the degree of Irritation. The sympathies which arc traceable to physical causes so explained ; we may see if the moral sym- pathies may not be reducible to the same causes ; and SYMPATHY. 51 whether, in fact, the whole of these phenomena, by whatever name they may be called, are not all the offsprings of nervous influence — " Si vis me Acre, dolendum est Pi'imum ipsi tibi." Plere, then, is a moral sympathy; the feeling of another's woes, who does not feel them himself, and whose male helief is convertible into reality in an- other mind. This is a strange state of things, and proves there is more in heaven and earth than we have dreamt of in our philosophy. The hireling on the stage shall cause the eye to weep, the breast to sob, shall produce loss of sense and motion, cause the image of death in the spectator of his assumed grief. This is not only applicable to the nervous and highly sensitive being, but it is the privilege of the boor as much as of the boarding-school miss. A boor in the pit of a theatre, not forgetting that he is there — for, as Dr Johnson has observed : " The spectators are always in their senses, and know from the first act to tlie last that the stage is only a stage, and the players are only players," — may be thrown into hysterics by sympathy. Dr Blair has given us a beautiful analysis of these sympathetic feelings in his essay on the effects of tragedy. Johnson comes to this conclusion : " If there be any fallacy, it is not that we fancy the players, but that we fancy ourselves unhappy for a moment ; that we rather lament the possibility than suppose the presence of misery, as a mother weeps over her babe, when she remembers that death may take it from her. The delight of tragedy proceeds 52 SYMrATIIY. from our consciousness of fiction. If we thought it real it would please no more." — Johnson's Preface to Shahespeare. Thus the boor is made to do what he never did before, because he never was made to feel that such a thing could happen to him. It is with him the creation of a new^ feeling. He sympathizes with himself. Now what may not be, strictly speak- ing, morally real, is so, physiologically. Whether the passion be real or not, the tears are substantially so. Weeping may be voluntarily or involuntarily ; the secretion takes place ; and as we cannot deny the influence of the nerves in the first, why should we in the second instance ? In this action we witness the transition from the one state to the other, so that we cannot separate them. A person may shed tears by the influence of his will, but may not be able to refrain from doing so when they have begun to flow. All the eftbrts he can make shall not force out a drop sufficient to lubricate the globe ; all his efforts to command them shall not pre- vent their flowing down his cheek. How are the mental emotions producing increased secretion of the lachrymal gland, — how is this weeping sympathy to be accounted for physiologically? Truth may here be said to spring out of fiction. It must be remembered that perceptive sensation is in the brain, as proved by the existence of local pain and sensations in parts long removed ; and as Mr Trnvers has observed, that the operation of dividing the fibrils of nerves for neuralgic aftections is of no use ; and this must ah\ ays be the case if the trunk of the nerve which communicates with the brain be SYMrATHY. 53 affected ; for, as Miiller states, the trunk contains in itself all the primitive fibres distributed in the branches of the nerve to the skin. The division of a nerve will only give relief when the disease is seated in the branches, not in the trunk of the nerves. — P. 744. The knowledge of this circumstance has come ra- ^ ther too late in the day for those, and they are not ^ few, who have allowed their faces to be mutilated *; again and again by the surgeon's knife. It affords us "^ the greatest encouragement to prosecute our inquiries into the actions of the nerves in health and disease ; and is a justification, to a certain extent, of ex[)eri- menting upon living animals, but none for repeating them from mere curiosity.* In the functions ascribed by different physiologists to the uses of the sympathetic nerve, there is great discrepancy of opinion. The subject, as Mliller ob- serves, is involved in great obscuHty. He, however, applies the same laws to it which govern the action of the cerebro-spinal nerves, and advances the hypo- thesis : — " When, in consequence of impressions on sensitive nerves, secretions take place in distant parts, the brain and spinal chord are probably the mediiun of communication." As regards sympathy it is evident that, in a phy- sical sense, it is not the sympathetic nerve which is alone concerned. The circumstance of the wide- extended connexions of this nerve, by means of its ganglia, &c., forming, as it Avere, a nervous web, the meshes of which communicate with all the other * Soe Appendix. 54 STMPATHT. nerves, has given countenance to the idea, that all nervous affections, morally and physically, might be thus explained. Now, as regards the secretions, we may observe, that this sympathy may be accounted for in three different Avays ; and all reducible to one action on the sensorium. Thus, the palpable impres- sion made upon the sensitive nerves of the tongue, shall produce an instantaneous flow of saliva into the mouth ; and this can only be caused by an increased secretion from tlie glands, wliich must imply an in- creased mass of blood in their structure, to be so A\ orked upon and eliminated ; and this again must be produced by the reflex action of the sensitive on the motor nerves of tlic brain. It is not necessary for this secretion that the sen- sitive nei'ves should be mechanically made subject to impression, because the same effect is produced by the impression of sight, for the mouth Avill water when the eye beholds a dainty morsel. The assist- ance of this even is not necessary, — recollection is quite suflficicnt to produce the same effect. It has before been stated that the cry of the child causes a flow of blood to the mother's breast, for the blood must be there before the milk can be elaborated. '• Every part of the body has its proper seat of repre- sentation in, and chain of connexion with, the brain : thus, to a certain extent, we can call up sensation by imafjininof it."' Muller observes, " The female mammary gland receives its nerves, not directly from the sympathetic, but, as it appears to me, only from the third and fourth intercostal nerve.*' And he states, that the SYMPATHY. 55 cerebro-spinal, as well as the sympathetic, appear to liave the function of regulating secretion. — P. 517. " The organic system of the great sympathetic nerve on the one hand, and on the other, the cere- bral and cerebra-spinal structure, with its nerve, tlieir boundaries and blendings, their direct and re- flex functions, forming the system of animal life, of perception, sensation, and motion, — involve the harmonies and sympathies which are, more or less, auxiliary to life in every possible variety of circum- stances ; and if not indispensable to existence, the intellectual faculties of which they are also the seat and instruments, are among the most powerful agents, as they are the most characteristic interpre- ters, of human maladies." — Travers^ Injicnnniatlon^ &.c. p. 18. In the innumerable varieties of moral and physical effects which present themselves in our present state of existence, and in its relations with the things which surround us, and which, for want of a better term, we impute to sympathetic influence, we can but recog- nize the direct influence of the nervous power, and refer the phenomenon to its control. It is under precisely the same direction, that if the sensitive nerves of the eye are oflfended by the pre- sence of a grain of sand, the lachrymal gland pours out tears for its relief, as in a moral sense : — '• When I did name her brothers, then fresh tears Stood on her cheeks." That definition of sympathy, " the aftection of one part of tlie body directly by the aflTection of another, 56 SYMPATHY. through vital agency alone, independently of physical," cannot be correct. Sir Pertinax Macsycophant said that he could never stand straight in the presence of a great man, — he bowed, as it were, by instinct ; still the bowing was a voluntary act of the brain by some unknown or in- definable impression made upon it. The brain may have the privilege of directing its powers in any way it pleases. If a pinch of snuff offend the nose, or the glare of the sun the eye, the impression is stiU made upon the brain through the medium of the nerves. It is an offending agent, and it is at the discretion of the brain, in which perceptive sensation resides, to put such powers into action as shall best get rid of the offendino; a^ent. In the effort of sneezinj^, the eve and nose are both relieved. Now, the force of habit conquers this very sensation. The habitual snuff- taker no longer sneezes, the snuff is no longer an offence, and the brain takes no cognizance of it, beyond the agreeable impression of its odour, and the stimulus it affords. In the remote sympathies which pathology affords, there seems to be no real contradiction to the law, that all true sympathy is effected by nerves, as Dr Elhotson maintains : " If we cannot explain the occurrence or absence of sympathy by nervous distri- bution, we must remember we are imperfectly ac- quainted with this." In the affections of the parotid gland we find the testes of one sex, and the breasts of the other, sympa- thize. This merely proves that the parts of the brain, receiving impression from the sensitive nerves SYMPATHY. 57 of the gland, transfei' tlicat influence to other glands, for the tumefixction of neither can occur without the direction of this organ in distributing more fluid to the part ; so that, directly or indirectly, the nervous system must be implicated, and Miiller ascribes this to the principle of reflection in this instance. There is positive evidence of sympathy being seated in the nerves. " In sympathetic muscular movements the sympathy is not between the excited part and the muscles, but between it and the nerves of the muscles ; wherefore, if the nerves of the muscles be divided, the sympathy still exists, but ceases to be manifest, be- cause the muscles are no longer influenced by the sympathizing nerves." " The iris ceases to contract when the third pair is divided, though light glares on the retina ;" nor Avill it contract if the latter be insensible by disease. So many proofs are afforded us of sympathies traceable to physical causes, and to direct or in- direct nervous communication, and the laws of re- flection, that our imperfect knowledge of this com- plex system at present may be fairly argued to be the only barrier to reducing all to one and the same cause. Dr Marshall Hall's view of the sympathies merits due attention, and must be read with great interest ; but it is impossible to make works of this kind duly appreciated by a few extracts. The whole bears upon every part ; but each single part conveys no accurate idea of the whole. 58 PHRENOLOGY PHRENOLOGY. " The brain is the mansion of the mind, and the index of its powers." The shape of the head has been looked upon in all ages as indicative of mental facul- ties. It must be boi'ne in mind that the skull is modelled by the brain, and not the brain by the skull. Every protuberance, every indentation, con-esponds with the shape of the cerebral mass within, and this is not always confined to the adult period. The same power of exercise which developes the muscular fibre will act upon this nervous mass, and extraordinary occupation of the mind will change the form and in- crease the size of the skull long after what is termed the full period of growth. Napoleon offered a strik- ing example of this phenomenon. " On peut en citer un exemple, le plus connu qu'on a observe, dans la personne de Napoleon, dont la tete peu volumineuse, dans sa jcunesse, avait acquis depuis, quelques annees un developement presque enorme.'' — Diet, des Sciences Mediccdes. The shape and size of the head are not infallible guides, but they have the experience of ages in their favour ; and Mr Abernethy has observed, that a Greek sculptor never placed the head of a philoso- pher on the shoulders of an athlete. It avIII be long before phrenology can be ranked amongst the sciences, for there must be a crusade in all parts of the globe, and the examination of thousands of skulls, and a knowledge of the moral characters of their owners, before the basis of this theory can be solidly esta- blished. PHRENOLOGY. 59 Lavater is too much forgotten in the present day. His facial angle cannot but persuade those who study- it carefully, that they can read the man in his phy- siognomy. There is nothing repulsive to religion or morality in these doctrines. The same Almighty power which created the whole may liave assigned different functions to its parts. AVe are not all created with tlie same moral or physical powers : St Paul has said that some enjoy gifts which others do not. But all phrenologists are not agreed as to the seat of the organs of specific moral qualities ; and so long as there can be any doubt upon such a point, the whole science must dissolve as the baseless fabric of a vision. No doubt exists as to the seat of sound in the audi- tory, or of sight in the optic, nerve ; and the demon- stration m.ust be as complete as regards the endow- ment of certain portions of the brain with respect to tlie moral functions, as to the physical. Mr Travers has well observed, " Cerebral regions and cerebral agencies, are as indispensable to the production of local physical sensations as to the operations of the mind. The phrenological system, I may here remark, owes its existence to the countenance which it derives from a twilight of truth, though only sufficient to serve as a beacon to the absurdities with which it is enveloped." — Physiokxjt/ of Inflammation, <fec. It is sometimes objected to phrenology, that it is an apo- logy for immorality and crime, and that the vicious may screen themselves under its cloak. This objec- tion, however, cuts both ways, for if our actions or propensities depend upon organization, then to do good or ill is not voluntary on our parts. We should 60 PHREXOLOGT. not have more power to do ill in one case than of re- fraining from it in the other. That certain states and conditions of the brain do influence moral actions, is beyond all doubt. Not only do the various forms of insanity prove it, but also the unconquerable propen- sities manifested by some who are still reputed of sound mind. The disposition to steal is not unfrequently innate, where no plea of want can justify it. I knew the son of a Polish nobleman who had this propensity, — nothing could cure him. All means had been tried, the mildest and the severest, but to no purpose. There are few shopkeepers in London who cannot point out persons of rank who will readily lay out £100, yet, if they have an opportunity, will steal a yard of lace. It is useless to multiply similar instances. Accidental circumstances coincide in ffivinjT great weight to the opinion of physical cerebral derangement influencing the moral man. The most pious have been made re- probates by a fall from a horse. I, myself, knew an instance of a highly gifted youth becoming a dull, foolish man from this very cause. He laboured under convulsions for some time, and recovered all but his senses. Dissection does not always aflTord us sufficient phy- sical evidence. Our senses are too obtuse to identify these subtile conditions, but we have sufficient moral proofs that something does occur, — that some charge in the balance is eflTected, some disorganization of the nervous mass ; for Ave find friends and relations, with whose well regulated conduct we have been all our lives conversant, launch out at once into the most extrava- gant course of life, sometimes without apparent provo- PHRENOLOGY. 61 cation, while at others we attribute it to some verj iinsatisfactoiy cause. I do not alhide to temporary delirium or febrile excitement, but to genuine mania ; not evanescent as the former, but permanent for the rest of life. These effects must have their cause some- where, however inscrutable they may be. It is not in the blood that we are to look for them. Aii inflamed condition of this fluid may produce temporary mental derangement, which will subside when the exciting cause has been removed ; but it is not in the circulation that we can trace any clue to the state in question ; yet how common and mischievous has been the practice of bleeding under these circumstances. It is not, perhaps, too much to say, that this state has been per- petuated by such practice, when a diffusible stimulus, a dose of o])ium, might have cut it short. We must refer such states to a change in the condition of those parts by which the passions are expressed. Dr Gall has related the following case in point : — " A young man who was trepanned for an injury of the head, lost a portion of the upper surface of the brain in the ope- ration, the wound healed, and he recovered. From this period he evinced the most unconquerable pro- pensity to steal. In spite of the severest chastisements, he carried this practice to such a pitch, that he was at length condemned to the gallows. He expressed himself pleased at the circumstance, for he was con- vinced of the impunity of his proceedings, and said that he had no hopes of ever being able to correct himself." The subject of phrenology is one of too much im- portance to be discussed in a cursory manner, or by 62 PHRENOLOGY. the non idonei. It was impossible, however, not to touch upon it in discussing our present subject. Al- though, I believe, I have mentioned It elsewhere, still I must relate the following instance of Dr Spurzhelm's skill in ascertaining the moral and physical characters of a patient, who was long under my care, from a simple examination of the head. I bad the charge of a child five years of age, whose brother and sister had died about the same age of hydrocephalus. I requested Dr Spurzheim to see her. She was in good health at the time, but was considered to be threatened by the family disease. I had made some changes in the plan of treatment, both moral and physical. The child was subject to headaches and debility, and her mind was so lively to any impression, that if a fairy tale were told her by her nurse at night, she would dream of it, and act it in her dreams. She would sit up in her bed, and perhaps get out of bed, and walk and talk in her sleep. These symptoms being considered as indications of approach- ing hydrocephalus, she was kept very low, and calo- mel purgatives continually administered, by which the debility was naturally increased. Taking a different view of the case to that which had been taken by my predecessors, I ventured to change the whole plan of treatment. If a day had passed without the bowels being moved, a dose of calomel was always given, and then, after its effects, constipation would recur, and again the same remedy. Her diet Avas confined to soup and vegetables, and exercise in the open air was proscribed as too much for her strength. I had many prejudices to overcome before I could persuade to a PHRENOLOGY. 63 diiterent plan of treatment, and my responsibility was very great, for the child was motherless and in the hands of menials, her father not being able to reside with his daughter for a long time together. Consi- dering air and exercise essential to the well-being of childhood, I put a donkey and very large Chinese parasol in requisition, by -which means an hour's exer- cise round the town could be obtained at any time of the day without fatigue or annoyance from the sun. The diet was changed. Soup and potatoes were dis- missed from the board, and mutton and poultry, in moderate quantities, were allowed daily. This, with baked fruits, constituted the dinner meal. Very weak tea and milk, with bread and butter, were the break- fast and supper repast. Some ripe fruit was permitted in the afternoon. As regarded the torpid state of the bowels, I avoided medicine, and my great difficulty Vvas to break through this habit. Common enemas, however, answered the purpose ; but so rapidly did an improvement take place under the change of diet and exercise, that the bowels acquired a proper tone, and performed their functions Avithout interference. The moral education required as much attention as the physical. Ardent, irritable, and impetuous, impatient of control, and highly susceptil)le, all this was to be overcome, or rather she was not to be placed in the way of excitement. I requested that education, or such as consists of reading and writing, should be dispensed with, for at least some months ; and as an improvement had taken place physically, I had gained confidence enough to be allowed to recfulate the moral system. No books but picture-books, no 64 PHRENOLOGY. cards, no draft-boards, were allowed ; nor did I per- mit, after a certain time of day, any histories or stories to be recited or read to the patient : an im- provement ^Yas as soon visible in the night as in the day. The sleep became more tranquil, and the talk- ing and agitation less, not suddenly, but by degrees ; as the body waxed in strength, so did the mind. It was after a six months' trial of this plan that Dr Spurzheim saw her by chance. I told him merely what the fears were as regarded the tendency to hydrocephalus, which was hereditary in the family. He could have known nothing of her history. Upon examining her head, he said you have nothing to fear, she will do very well, but avoid all moral excitement ; her brain is weak, and she must not be pushed beyond her powers at present. When the physical substance is stronger, the external impressions will do less harm : but let her run wild, leave her education alone ; let her amuse herself as she likes ; dont contradict her. She is irascible, impatient of control ; this will improve by degrees, but do nothing to call it forth ; humour her. He drew her character to the greatest nicety in every particular. I then explained to him the treat- ment I had adopted, and what had been adopted previously. It is her only chance, he replied, and you have hit the mark ; continue all you are doing, and you will carry her through in triumph. As far as I can recollect, these were his very words. The impi'ovement was gradual, but solid ; and as she got stronger, her education was commenced paula- tim, but she was not permitted to stiidi/ till she had attained her tenth year, when all predisposition to PHRENOLOGY. 05 disease vanislied. I had, by request, kept a journal of the medicines Avhich she took during the five years she was under my care ; this had Ijeen done by my predecessor, and, on comparing the two, it was found that more calomel had been administered in any three months previously, than during the whole of the five years. She had been treated for a disease which did not exist, but which was anticipated; and the means employed to ward it off, would most probably have brought it on. She had but one severe illness during the whole of this period. She was suddenly attacked, when riding on her donkey, with a pain in her head, followed by severe headache-delirium, great constitutional fever, which, however, yielded to common antiphlogistic treatment. In the commencement, she Avas very subject to slight but sudden attacks of pain in the head, which would occur without any assignable cause, and were, for the most part, of very short duration, but always left her very languid. These seemed to warrant the employment of calomel. In detailing this case so minutely, and perhaps un- necessarily for those who have met with many such, it must be remembered that it Avas one of great respon- sibility, and upon Avhich all my future career hinged. To those Avho have practised twenty years it ofiers nothing new, but young practitioners may be placed in the same situation as I Avas at that period, Avhen all their knoAvledge is derived from books, and to such it may not be uninteresting, as proving how much may be accom})lishcd by measures Avhich apply to the general health only, and hoAV much is to be feared (j\j rHRENOLOGY. from precipitate medical interference, where disease is rather threatened than existing. When in Edinbui'gh, I was cHnical clerk to the late Dr Entherford, with whose memory are associated most grateful recollections, and from whom I received most marked kindnesses. His practice was considered by the students, who know so much, or think they know so much, as puerile and inert, and his visits drew but few followers into the wards. Cases, which seemed to iis to demand the most active treatment and a free use of the lancet, were treated by a saline diaphoretic mixture and a foot bath, and got well under such treatment. He once said to me, with a smile, iny practice differs from that of my colleagues ; but it is my object to let the students see how much nature ^v'iIl do in many instances, and how patients recover under the most simple treatment, and by the removal only of all exciting causes. It is too com- mon with you all to ascribe every thing to the medi- cines you administer. The veiy active treatment you employ relieves the symptoms, and you take great ci-edit to yourselves for your decided practice ; but you forget that long convalescences follow, and tlie constitution is shattered and impaired by such abstrac- tion of its powers. You will find that patients who have been apparently cured by large bleedings which have conquered pain in the first instance, remain eventually longer in the wards than those who have not been so speedily relieved ; moreover, you will find them return again, after their dismissal, with dropsy and chronic aflPections. As regarded bleeding, the Doctor never took away more than from eight to MESMERISM. 67 twelve ounces at a time ; and now, after a period oi twenty-five years, his vie>vs of things, and those of his colleague, Dr Gregory, seem to have been correct; for, as the latter has beautifully expressed it, " Nam ut sanguis semel missus nunquam in venas redit, sic neque vires cum illo amissaj in variis morbis unquam refici possunt." The change in this part of the treatment of disease has undergone great modifications, and practitioners no longer boast of their bleedings, ad deliquium, which thev did formerly. This decided practice, as it was styled, and which usurped the claims of confidence, is now proved to have been decidedly bad. I am indebted, perhaps, to the admonitions and example of the discoverer of Nitrogen for tlie success with which my treatment of this case was happily crowned. MESMERISM. This subject must be considered physiologically and morally. In the latter sense it surpasses any- thing which can come within the cognizance of our senses, and, at all events, is out of the pale of medical inquiry. The exhibitions Avhich we have daily made before us, if true, can only be referred to the class of miracles. It may not be amiss to warn tlie public how far, and by ^A'hat complication of machinery, systematic imposture may be carried on. We refer to the Appendix for an extract from M'Crie's Life of John Knox. 68 MESMERISM. Considered physiologically, it may be asked what is true, and what is new in these histories ? and whether, in this view, the whole be not reducible to excited nervous influence, which has at all times pre- vailed under particular circumstances, without usurp- ing any specific name or term ? There is nothing new in the discovery, that pain may be suspended by moral impression ; the number is, perhaps, comparatively few of those who have not proved this in their own persons. The pain of tooth- ache is recognized to be as severe as any to which flesh is heir, — the stoutest are knocked down by it. The celebrated Tom Crib was deprived of all his muscular force during a fit of it ; and yet this agoniz- ing pain, this torture Avhich often makes a man run his head against the wall, is entirely dissipated, not mei'cly for the moment, but for weeks ; — not by oils and opiates, not by the extracting iron, but by the simple rap at the' door of him who is supposed to have the irons in his pocket. The fear of incurring a momentary pain still more severe than the one in operation, is suflficient to expel the latter. "\Ve require no name for this phenomenon ; Ave speak of its eflfects ; and we see, in this instance, that moral causes can operate upon the nervous system, and suspend physical action ; the pain in question being referable to irrita- tion of the nerves. If the passions of the mind, of which fear is one, be still more Avrought upon, the sentient condition of the nerves may be so paralysed as to allow the tooth to be extracted, or the limb to be amputated, Avithout causing pain to the patient. I see no reason to doubt of the veracitA^ of these Avit- MESMERISM. 69 nesses ; I can find no object in deception, no reason to suspect collusion, because there is nothing more extraordinary in the effects of the will directing all its powers to the consummation of one object, than that this should be effected by the operation of one passion. It is the faith which removes mountains. This is a word Avhich seldom finds entree to medical levees ; it sits at the gate like Mordecai, and it is sure to triumph. It will finish by hanging its foes, Scepti- cism and Credulity. It is the same that cured the woman of hemorrhagy, and the man at the pool of Bethesda. AVhy should we suppose that its reign is over ? It is as paramount in the present day as in times gone by. It has existed from the beginning of time, and will endure to the end. It is a part and parcel of our moral existence. It represents a great power equal to a host or army, exercising its influence over our moral and physical being. It is not at our own dis- posal ; it is not in the power of all to believe ; but those who do, and do in right earnest, often reap the fruits of what some Avould style their weakness. — How strong in their weakness. None are so well acquainted with it as those who found systems upon it, which last as long as they can fan the flame ; for it will some- times go out, and may not be rekindled. We appeal to the Ilomoeopathists to tell us what they have accomplished by knowing how to avail themselves of this power. We return to the influence of the will over tlic physical man — over the muscular system, and we shall find that, by continued cftbrt of this will directed to one object, the distorted arm — the contracted leg, have been restored to their normal 70 MESMERISM. state ; as has been proved in our own experience. We see the muscles only through the nerves ; the older physiologists believed them to be expansions of the latter. Mr Hone, in his Every Day Book, relates the following instance of extraordinary muscular ex- ertion: — A man with a wooden leg was leaning against a high gate, when he was suddenly alarmed by the sight of an enraged bull coming full speed at him down the lane. There were no means of escape, and death or horrid mutilation seemed to await him. Under this excitement of fear he made a violent effort, leaped over the gate, and escaped from his foe. Some soldiers in the late wars, under the full excitement of victory, stormed and took a fort. The following day, upon seeing what they had done, they could hardly believe it possible ; they doubted their own achievements. Their commanding officer ordered them to renew the attack in a sham fight ; not a man could mount to the point where he had placed his foot the preceding day. It was a sham fight ; the stimulus of reality w^as wanting to assist the will. A man has been confined to his bed by a fit of the gout, and so perfectly helpless as to require the aid of several men to move him from one side of the couch to the other. In the middle of the night he has been suddenly alarmed by the house taking fire, when he has, without any assistance, jumped out of bed, run down stairs, and gained the street. It is useless to multiply cases of this nature. It may be allowed to draw a parallel between them and some of those effects attributed to mesmerism, and see in what they differ physiologically. MESMERISM. 7 1 The most striking instance on record of the power of the Avill over muscular motion, is presented to us in the case of Colonel Townsend, Avho could, by voluntary effort, suspend the action of the heart for a considerable time, during which he lost all appearance of life. Is there anything in all the distortions and monkey tricks, which we see those exhibit who are said to be under this mesmeritic po\A'cr, so wonderful as this ? tlie suspension of the heart's pulsation by voluntary effort ? I A\itnessed, when in St Petersburg, some children exhibit a great many pranks when mesmerized by a female magnetizer of the name of Tutchanienoff. These children had all some physical defect ; one had a hump on his back, a second, a distorted spine, a tliird, a contracted limb, &c. She promised to put all things straight by the power of her eyes. She Avas of middle stature, very dark complexion, with piercing ])lack eyes. She exhibited in public. She Avas seated in a corner of the room, wore a dark blue riding habit, and had a black velvet cap, with gold tassel, on her head. The children were admitted. They had sallow complexions, were meagre, and in bad condition. They were told to approach her. She avoided looking at them for a time, during which they remained quiet. She suddenly turned her head towards them, and gave a piercing look ; and at the same instant they com- menced their antics. The boy with the hump back took up a folio book, liolding a lid in each hand, and throwing it over his head, thumped the hunch with the body of the leaves. Some muscular power was 72 MESMERISM. employed, but the thumps were not hard enough to hurt him. The contracted arm was pulled by two attendants, one holding the body, whilst another pulled at the arm, and the child vociferated krepka, krepka — pull harder, pull harder. The shortened leg was served much in the same way. This continued for about two minutes, Avhen the exhibition ceased. As soon as the magnetizer turned her eyes from them, the children were powerless. Several of my colleagues were present, and we all agreed that a greater piece of imposture was never attempted. No good was done to the children. This woman continued to per- form her miracles for a long time in St Petersburg, patronized by the nobility. Amongst other feats, she was said, by her look, to have caused long thread-like bodies to issue from the digital extremities of a child, which, from some vibratory motion which they mani- fested, were said to be living Avorms. Still all is not imposture. It is but fair that I should relate the following case as coming under my own cognizance, and that of most of my colleagues. A lady, the wife of a physician, met with the following accident : — Her foot having slipped in mounting the steps to her door, she fell down the area, and concussion of the spine was the consequence. She lost all power of motion in the lower extremities. Various means were resorted to : blisters, setons, frictions, with tar- tarized antimony, galvanism, and, finally, she suffered the excruciating tortures of seven moxas burnt upon the sacrum, at different periods, — all without eftect. She remained a cripple, without any power of moving her limbs, and this for the space of twelve months. JIE.SMERISM. 73 She was carried in a litter to the steam-boat, which took her to Paris by Havre. Upon her arrival there slie was treated bv Recamier. He introduced a series of setons from the nape of the neck to the sacrum, but with no better effect. She was a woman of e-reat moral courage. Kit desperandam. She resolved on trying magnetism. A female treated her, and in six weeks she was going the rounds of a gay Parisian life, with her limbs perfectly restored. This was called mesmerism. Let us instance a case Avhere no sucji power was employed : — In the town of Southam[)ton lived a shoemaker who had a short leg ; he walked upon the point of the toe wdth the help of a stick, and was nicknamed " Hoppy." He had been in that state for years, and was knoAMi to the whole community. The days of acupuncture arrived. AVhat has become of it ? One of these operators visited the town and blew his trumpet. He performed many cures. " Hoppy" presented himself. He undertook to make him walk straight. He pushed pins and needles into the foot, and in a short time the man left off his high shoe, the sole of the foot rested flat upon the ground, he walked without limping, and without the help of a stick. His cure, however, Avas not of long duration. This was acui^uncture. It may be difficult to account for such things, but to deny the evidence of our senses in such instances, is tacitly to give ourselves the lie. In neither of these two instances could there be a question of collusion ; the acts were performed, no matter by what means. In neither of them do Ave see more than has been recognized in the cure of 74 SLEEP. toothache by fear, in the wooden-legged man jumping over the gate, or the gouty man quitting his bed. In all we must admit a moral influence Avhich, for a time, sometimes longer, sometimes shorter, predominates over and controls the physical powers. This influence is, perhaps, always voluntary ; for, as regards muscular motion, it must be borne in mind that the voluntary muscles act independently of the manifestation of the Avill. Sleep-walking cannot be instanced in proof of this, for it is by no means clear that the will is not active in this state. Dr Whytt observes that many of the bodily motions are performed when Ave are insensible of the power of the will excited in their production. We are not aware that the eye-lids are kejtt open by the will ; but when drowsiness and sleep steal upon us, we find it requires a considerable effort to prevent the falling down of the upper curtain. In a physiological sense, all these apparently won- derful phenomena are true, but they are by no means new. Of the rest of mesmerism, as far as the opera- tions of the mind are concerned and its knowledge of things, these are new ; it will require undeniable evidence to prove them true. If they be, they rank with miracles, and are without the pale of physiology. See Appendix. SLEEP. In the few observations to be made upon a subject ■svhich has given rise to so much speculation, it Avill be evident, Avhether sleep be considered as a function SLEEP. 75 of the brain, or as resulting from an exhaustion of nervous power, it is this organ which is principally con- cerned in the process. In no function of the system does the blood play a more important part than in influencing this phenomenon. If it flow too freely, or its momentum be too great, (from Avhatever cause, moral or physical, this may arise,) it is fatal to sleep, and this effect is mechanical and independent of any change in its constitution. Some maniacs will resist sleep for days and nights together, if the nervous system be in a great state of excitement. Where the circulation is weak, as when the body is exhausted by fatigue, so irresistible is the power of sleep, that the culprit at the stake, and the mast-head midshipman, cannot resist its influence. Of the direct eflects of the circulation on this func- tion, proofs are afibrded us by compressing the brain, and large vessels which furnish it with blood. If the carotids be forcibly compressed, a state of sopor is induced. Sir Astley Cooper used to relate the case of a sailor who had been trepanned, the pulsations of Avhose brain were visible through the bony ring, which Avas covered only by integument ; and if the thumb were pressed upon this spot, sleep immediately fol- lowed. The state and condition of the blood must not be lost sight of in these matters ; for, as an increase of momentum in the arterial blood will cause insom- Jiolency, so will a diminished circulation, retarding tlie return of the venous blood, produce sopor and coma, and often apoplectic symptoms. Asphyxia is so produced. If a marchande de modes be crossed in love, she shuts herself in a small room, places a pan T(> SLEEP. of liglited charcoal on the floor, and Hes down to sleep the long sleep. — This is asphyxia. If the mind be excited at the usual time of repose, it is often preventive of sleep ; there is an increased vascular action ; and the Germans have a very forcible term for that tossina; and cjeneral restlessness of bodv accompanying this wakeful state, " Das Blut ist in Wallung." As long as this irritability is kept up by physical or moral causes, sleep will not be induced. John Browne, whose essay upon this function is the chef d'cenvre of his writings, insists upon a due balance between the exciting powers and the excitability as necessary to sound sleej). It is upon the principle of subduing the latter that opium acts as a diffusible stimulus. Me Uerde, he exclaims, opium non sedaf. Feeble doses of this drug, far from producing the de- sired effect, only increase the irritability of the system, and prevent sleep. I have often been surprised at the very small quantity of opium wdiich German practi- tioners employ with a Aiew of inducing sleep, not at the disappointment they experience. Physical and moral causes, as they are in due proportion or in excess, will induce or counteract the process. We understand the expression of an agreeable degree of fatigue, which invites to this state, as an excess of the same prevents it. Moral influences act precisely in the same way ; grief and anxiety repel, as tlie thoughts of anything pleasurable court, sleep. But these have also their limits, and sleep w'ill at last conquer in spite of the aggravated torments of mind and body. When witchcraft was punished as a crime, it was the great object of tlie torturers to keep the poor sufterers awake. SLEEP. (7 which they did by ninning needles into tlieir eyes. Sleeplessness is a characteristic symptom of insanity ; it often precedes it, and is one of the first of the many harbingers of this approaching malady. " If I do not get sleep I shall go out of my senses." is not an uncommon expression from those exhausted by long Avatchfulness. I have known some persons subject to confusion of intellect and waking dreams, who recover their mental energies by a five minutes nap. The force of habit, together with all the innumer- able causes which operate through the inliuence of ex- ternal impressions on the sensorium, the rustling of the leaves, the bubbling brook, the warbler's notes, the fairy tale, the more mechanical influence of the friction of the skin, will not allow us to doubt of the nervous power as one of great importance in the performance of this function. I have a patient at present Avith an affection of the heart, who is lulled to sleep by the nurse taking his hand in hers and tickling it. The child Avill not often go to sleep without the thumb in its mouth. In the language of Shakspeai'e — '' Our little life is rounded by a sleep." l»ut, nevertheless, it is not the image of death, nor is there any analogy between the two. Every function of life is performed during sleep. Respiration, which of all others is the most characteristic of life, so that to cease to breathe is to die, is never so well per- formed as in this state. As to the mental functions, they are, I believe, always awake. ]\Iemory may not assist us to recall what has passed, but it fails us in 78 SLEEP. many other circumstances. Some do not recollect that they have slept at all, and maintain the point in spite of credible Avitncsses to the contrary. I knew a lady avIio insisted that she never slept, and drank Burton ale when she ■went to bed to produce sleep. Being in the habit of waking up very often, she Avould not be convinced, even by the testimony of her husband, that she slept great part of the night. A gentleman, who was hurried to Paris by the distressing news that his son was dying, took a courier with him for expedition. They left town in the evening. 1 he man informed him that he never slept in all his journies by night. In less than ten minutes he was fast asleep, and only awoke at the different stages. On arriving at Dover in the morn- ing, he maintained that he had never closed his eyes. It is not logical to say that the mind is unemployed, because we cannot recollect what occupied it ; for we find memory very treacherous. The state of the somnambulist does not argue that the mind is asleep. The nervous system is awake ; for the muscles are controlled by the will, and there is a determination in the exercise of it. There is a decided object in view, for the movements are directed to some one point. There must be some degree of vision. The man on the roof top does not walk over the parapet, and seldom comes to harm, unless some foolish attempt be made to awaken him. Then there may be fear of his losing his senses and his life at the same time. Lady Macbeth was morally awake when she exhibited this phenomenon. There is nothing more capricious in its visits than SLEEP. 79 sleep. It treats rich and poor, the happy and un- happy, alike, as regards its favours. Some, in the enjoyment of good health, are most indifterent sleepers. " Mr Good gives us a singular instance of a man who never slept, and yet enjoyed a very good state of health till his death, which happened in the seventy- third year of his age. lie had a kind of dozing for about a Cjuartor of an hour once a-day, but even that was not sound, though it was all the slumber lie was ever known to take." — Medico- Clilnoyical Obser- vations. The people of northern latitudes sleep more than those of the south. The Russians boast that they can sleep at all times of the day or night ; and this, Avith the common people, is the case. Most part of their unemployed time is spent in sleep. The influence of sleep upon the faculties of the mind is different in different individuals, as is the refreshment which it affords physically and morally. The autlior of the Waverley novels has stated, that liis powers of authorship required seven hours of total oblivion for their full energy ; he was good for no- thing if he had not so much sound sleep in the twenty- four hours. I knew a gentleman of very nervous character, who was never so nervous, nor seemed so much exhausted, as after a night's sound sleep. The theory of Brown respecting the diffusible stimulus of opium, is not applicable to morphia, which indeed invalidates the theory. " That opium contains two principles, the stinnilant and narcotic, is not now matter of specula- tion ; as they have been separated chemically, and 80 ON Drj:A:.is. tlio narcotic part, morphia, can be used to produce sleep Avitliout the stimulant. The stupor from opium Avas said to be the sedative effect subsequent to, or produced by, the exhau^stion of the stimulus ; but this is not the case ; for, the stimidant part being taken away, the morphia produces sleep as certainly ; thus realizino; the lono;-sou2:ht desideratum of an unstimu- lating opiate." — Billing's Principles of Medicine, p. 87. ON DREAMS. Lord Brougham has hazarded the opinion, thiit dreaming is confined to that period which exists between the sleeping and -waking state ; and that, during sound sleep, people do not dream at all. Although, upon rising in the morning, we may imagine that Ave have been dreaming all night, yet if this state has prevailed, it has been by continual successions of transits from sleep to wake ; and as all standard as to time is lost under such circumstances, so the Avhole of the dreaming period, Avhich may appear to us to have occupied hours, is in reality accomplished in a fcAv seconds. It appears to us that the author has not made out a clear case, and that facts are opposed to this theory. The late Dr Cullen observes, in his Physiology of Sleep, that the body, as Avell as the mind, may be in any state of Avaking ; and as the latter does not go to sleep all at once, but by degrees, so it may aAvake in the same manner. ON DREAMS. 81 As regai'tls the amount of dreaming comprised in the shortest period of time, the idea is not new, how- ever true it may be, for Dr Darwin has advanced the same supposition in his Zoonomia. " The rapidity of the succession of transactions in our dreams is ahiiost inconceivable ; insomuch, that when we are accidentally awakened by the jarring of a door, M'hich is opened into our bed-chamber, we sometimes dream a whole history of thieves or fire in the very instant of waking." — Vol. i. p. 295 ; sect. xviii. 11. In the process of sleep the senses take their depar- ture seriatim. The eyes, covered by the relaxation of the muscles, which hold up the curtain, are no longer conscious of the real fonns of objects presented to them, although lioht be not alto^-ether excluded. They enjov as mucli visual power as some animals do at all times, and it is some time before the halo is quite extinguished. The ear is Ion"' sensible to sound after the functions of the eye have ceased ; and the tongue can still babble out some inarticulate words. The muscular system does not become torpid all at once, sometimes a leg or arm will take precedence of its feUow, fall asleep, or wake up without consent of its partner; hence the sensation in a limb as if it were dropping through, when we first fall asleep, or when anything suddenly rouses us. In the process of waking, the ear is the first of the senses which regains its functions, as it was the last to lose them in that of sleeping. It is susceptible of the impression of sound long before the eye is able to 82 ON DREAMS. distinguish objects, or the muscular power so much awake as to be able to lift up the curtain. This explains the phenomena to which Darwia alludes, of the dreams which take place in this inter- mediate state between the awakening and the broad awake conditions of the sensorium ; and as Cullen has advanced the proposition, both body and mind may be in any state of waking. As the senses, physically, are not able to perform their functions correctly if entirely isolated, but each requires, for the perfect performance of its own special duties, the co-operation of its associates, and runs into error when their correcting influence is suspended, so is the sensorium all abroad and dreaming, when de- prived of the combined influence of the external senses. The thieves and fires vanish, therefore, as soon as the eye has the power to correct the error caused by the insulated impression of sound made upon the ear. It is not to this period alone that dreaming is con- fined. It occurs during the soundest sleep, of which there are suflicient demonstrative proofs. If it were confined to this period, the slightest power exercised by a second person would be suffi- cient to awaken the dreamer, but this is not the case. ]Many who give sufficient evidence of their state of dreaming by the agitation of their features, and by vocal expression, require a good deal of external force to be exerted upon their bodies before they can be made to awake ; and we have known some of the hardest sleepers to be great dreamers, although upon awakening, they are not conscious of having dreamt at all. With many the dreaming state may be thua ON DREAMS. S3 recognizable to a bystander, and yet the dreamer shall have no recollection of Avhat he dreamt, nor can be persuaded that he did dream. Instances are not uncommon of persons waking in a dream by the effects of some external cause, and continuing the same dream when relapsed again into sleep, which proves that dreaming is something more than a succession of ideas crowding upon the imagination, during the period of moral and physical struggle between sleep and wake. Has not many a sportsman had opportunities ot proving, by ocular demonstration, that dogs enjoy the pleasures of the chace in their dreams. Has he not observed his spaniel, after a day's shooting, stretched out upon the rug before the fire, exhausted by fatigue, and enjoying sound repose, — and has he not heard him -uhine and groan, and, finally, give tongue in full cry, and yet so far from the transition state, as to requu-e a hard kick before his dream could be dispelled. This faculty of animals has been beautifully described by Lucretius, in the following lines : — " Venan tumque canes in moUi saepe quiete, Lactant crura tamen subito, vocesque repente, Mittunt, et crebro reducuiit naribus auras, Ut vestigia si teneaut invcnta ferarum ; Expt'rgefactciquc scquuntur inania soepe Cervorum simulacra, fugaj quasi dcdita cernaiit ; Donee discussis redeant erroribus ad se/' Liierd. lib. iv. O.'KI. " Spurzheim has observed, that some do things in their sleep of which they are incapable Avhen awake. J)r Good relates the case of a clergyman, who iiad 84 ON DREAMS. deeply cultivated music, to M'hich he was passionately attached, who composed during his sleep a very beau- tiful ode of about six stanzas, and set the same to very agreeable music ; the impression of which was so firmly fixed in his memory, that on rising in the morning he sat down and copied fi-om his recollection both the music and the poetry." It has been asserted that men have solved problems in their sleep which puzzled them in their waking hours, and, shouting out, Eureka ! they have awaked. THE FIVE SENSES. 85 PART V. Vision — Hearing — Smell and Taste — Feeling — Voice and Speech. THE FIVE SENSES. That tlicse faculties depend upon the perfect inte- grity of the nervous .structure, is a fact too well un- derstood to require any comment. In tracing some of those curious histories which result from various degrees of derangement and disease, the importance of its sound state will be best illustrated. This, however, opens a very wide field of inquiry, over which our limits will allow us to skim but lightly ; a very curious pheno- menon here fii'st presents itself, in the circumstance, that a certain relation and dependency exist througli- out the whole of the systems of created beings, and that even here the perfection of one sense is some- times due to the co-operation of another. Thus, the eye corrects the sense of touch, which again is sometimes requisite to correct vision. " The senses are not," as Spurzheim observes, " of themselves sufficient, inde- pendent of the internal operations of the mind. It is said that the senses correct each other, and they do so in a certain degree, but they do not correct the functions of the senses. Thus we see objects reversed, but the touch assures us they are not so, yet, having been convinced of this by the touch, we do not see 86 THE FIVE SENSES. them otherwise than as before. Some other power vi' the mhid is necessary for this." The organs of the five senses which connect us w ith the external world are subject to lesions of different kinds, by which they are no longer susceptible of impressions, or by which the impressions which they receive do not convey just ideas of things to the sen- soriiun. Tliese erroneous impressions allow of every variety of perversion, and are often productive of most unpleasant consequences. They may be often traced to mechanical injury ; and where this is not evident, still we must judge by derangement of function, that such must exist, although not cognizable by our senses. In the convalescence of fevers, we find that the senses ^vhich had been annulled during the disease return to their perceptive state by slow degrees, while some are more acute than in a natural state. It is long before the eye regains all its vigour. Taste and smell are obliterated or changed from what they should be. Deafness is of long duration, and the sense of touch does not recognize olijects pre- sented to it with the same degree of accuracy as in a liealthy state of the system. The mental powers long feel the injury done to the sensorium ; until it becomes fixed and steady the mind will continue wavering. Memory is sometimes lost for weeks. These effects will be found, iu general, to be in a ratio with the severity of the disease, and its mode of treatment ; in both cases it is the loss of nervous power, which is to be deplored. In those cases of general ill-health which are, ac- cording to Macculloch, ascribable to obscure inter- THE FHTE SENSES. 87 mittents, this morbid state is found to prevail very greatly. He traces it to direct influence on the nerves themselves. " Nor is that consequence a secondary one, origi- nating in false or perverted moral views, or in an alierration of the reasoning faculties ; since it appears on the contrary, where that does or does not exist, and to be absolutely an insensibility or a primary disorder in the nerves of those organs of sense which are the mediums of pleasure." Thus, some have complained, " that beautiful ob- jects, such as pictures, natural scenery, and so forth, Avhich, when in health, had been most pleasurable or engaging, seemed to make no impression at all upon the sense. So those who, as musicians, were accus- tomed to delight in music, not less from science than feeling, complained that they seemed to sufl:er under a positive insensibility as to what used to be a source of the most refined delight, although labouring under no affection of the temper, nor any of those sensa- tions commonly called hypochondriacal; and thus have others complained that the most gratefvd things had ceased to give pleasure, — that the scent of a rose was not only powerless, but produced absolute pain, by reminding them of what it once Avas, while every attempt to revive the former association connected with this and other similar objects of delight was un- availing." — ^facculloch, vol. i. p. 324. The effects of derangement of the nerves are illus- trated by the fact, that " external agencies can give rise to no kind of sensation which cannot also be pro- (Uiccd Ijy internal causes exciting changes in the con- 88 THE FIVE SENSES. dltion of our nerves/' A constant action may tlius be going on internally, and keeping np impressions which distress the hypochondriacal ; and although aris- ino- from within, are as real sources of uneasiness, as if visibly exerted from without. The senses of seemg, hearing, smelling, tasting, and feeling, may be all excited by internal causes without any exciting ex- ternal agent. An increased determination of blood to any of these parts will increase their susceptibility, and excite sensations. Moreover, all these things are accomplished in our dreams ; and the direction of the mind to any one physical ailment will increase it as much as the influence of external impression. If it be established that each organ of sense is capable of but one kind of sensation only, and not of those proper to the other organs of sense, and that one nerve of sense cannot take the place and perform the function of the nerve of another sense, " Still a strong impression made upon a nerve of sense will, by reflex action through the sensorium, excite other senses. There is, however, no power of transposition of one nerve's function to another. The eye cannot hear, nor the ear see, nor did Miss JNIacaulay ever see with her fingers ; but the power of any one sense may be so increased by exercise, as in some measure to com- pensate for the loss of another by increase of its own function, v.'ithout in any way performing that of the lost one. This is very important as regards the sup- posed power of those who see through the skin in the mesmeretic state." VISION. 89 VISION. The integrity of the optic nerve is necessary to vision ; but many circumstances may prevent light getting access to it ; or light may reach it and make no impression upon it if it be too much disorganized. It wastes away for Avant of use, as other parts of the svstem are found to do. It is of some disordered functional states, and not of organic lesion, that any mention is to be made at present. These states may arise from physical causes, which may be either suf- liciently evident, or so obscure, that we cannot recog- nize them. A certain definite time is necessary for tlie impression of objects to be transmitted through the nerve to the brain, and there be painted in their real form. Hence the explanation of all jugglers' tricks, that motion is quicker than vision. This is the explanation of all the rotatory toys : however distant the objects may be in the disk, the rapidity of motion so blends them together, that they form but a single impression on the brain. Seeing double implies some physical derangement. It may be transitory, as when produced by too free potations, and wearing off as the fumes of the liquor evaporate. The story is well known of two able states- men of former days going to the House of Commons after a banquet. On taking their seats, one said to the other, why, I can't see the speaker ; not see hiin ! said his friend, I see two. But this state may be more permanent. I attended an old gentleman in St Pctersburtr Avho laboured for three weeks under 90 visiox. determination of blood to the head, during the whole of which time he saw everything double when both eyes were open. It is when the brain and nervous system have been shattered by moral causes, or by the sequela of phy- sical ones, that the most curious phenomena occur, as regards the visual powers. The author of the Diary of a late Physician has published a ludicrous paper of the spectre dog which followed the man wherever he might be ; he could not shake him off, either in his walks, or in his bed-room, or in the stage coach ; the dog was always there. I know not whether this story be founded on fact or not, but a case very similar occurred in a gentleman, who related it to me : — In great distress of mind, he had taken a quantity of laudanum with the intent to poison himself. It did not accomplish what he intended, but was productive of most distressing nervous affections. Among others, as soon as he was in bed at night, he saw a dog lying at the foot of his bed upon the floor. He got out of bed to verify it, the dog vanished ; when he returned to his couch tliere was the dog again. The most singular item in the history was, that his mind could not rectify the error ; the visual impressions overcame the rational powers. He would leave his bed two or three times in the same night to be shamed by a phantom, and this lasted for full six weeks. At a subsequent period, and previously to his death, which was a melancholy one, he was haunted night after night by a chess-board with men upon it. That ghosts and apparitions have appeared to people cannot be doubted. Carlyle has alluded to the history VISION. 91 of Luther and the blue-bottle fly, and referred it naturally to that imperfect state of the sensorial powers when debilitated by physical exhaustion or moral causes. It is not true that there are ghosts in sub- stantial forms, paradoxically expressing it, but they are visible to the mind's eye. It is nowhere recorded that two people ever saw a ghost at the same time and in company. It might so happen, that of two men walking down a lane at night, one should fancy he saw a ghost and point it out to the other, whose fear might persuade him that he saw something ; but no two men at the same time, and in each other's com- pany, ever saw the same spectral form before their eyes. It is true that Shakspeare makes the ghost of Hamlet's father appear to Marcellus and Bernardo, and afterwards to Hamlet in their company ; but this may be accounted for under circumstances as Avhen — " Time is out of joint." The best ghost story of modern times is to be found in Southey's Life of Wesley, to which I can only refer, as it is a very long one ; but it is evident that the author placed implicit confidence in the truth of the whole history. Dr Ferriar Avas one of the first to give some rational explanation of these seeming wonders. It is reducible to physical certainty, that the im- pression of some bodies on the sensorium lasts long- after the object which caused them is removed from sicfht. After lookinji; at the sun for some time till we are blinded, for, as Lucretius observed, " Sol etlani coucat, contra si tendere pergas," 92 VISION. Ave see the globe of fire a long time. In cases, there- fore, where the mind has long dwelt or has been for- cibly impressed by any circumstance, it forms the subject for a night's dream ; and, as this dreaming state is performed sometimes in a semi-waking state, and when vision may be in some measure in function, so almost any object may substantially represent the mind's picture ; and this illusion may be more com- plete and permanent, as a certain degree of fear with the timid may prevent them from verifying the object by actual examination. The following will go far to prove how such things have oecm'red and found their explanation by close examination, and will also sug- gest the idea, that, for want of this alone, many semblances have been recorded as realities. " A traveller, benighted in the remote Highlands of Scotland, was compelled to ask shelter for the evening at a small lonely hut. When he was to be conducted to his bed-room, the landlady observed, with mysteri- ous reluctance, that he would find the window very insecure. On examination, part of the wall appeared to have been broken down to enlarge the opening. After some inquiry, he was told that a pedlar, who had lodged in the room a short time before, had com- mitted suicide, and was found hanging behind the door of the house, and to convey it through the window was impossible without removing part of the wall ; some hints were dropped that the room had been subsequently haunted by the poor man's spirit. The traveller laid his fire-arms, properly prepared against intrusion of any kind, by the bedside, and retired to rest, not without some degree of apprehen- VISIOX. i)o tiion. He was visited, in a dream, by a friglitful apparition, and, awakening in agony, fomul himself sitting up in bed witli a pistol grasped in his right hand. On casting a fearful glance round the room, he discovered, by the moonlight, a corpse dressed in a shroud reared erect against the wall, close by the window. With much difficidty he summoned up resolution to approach the dismal object, the features of which, and the minutest parts of its funeral apparel, he perceived distinctly. He passed one hand over it, felt nothing, and staggered back to the bed. After a long interval, and much reasoning with himself, lie renewed his investigation, and at length dis- covered that the object of his terror was produced bv the moonbeams forminoj a lono- bright imaae tiu'ough the broken window, on which his fancy, impressed by his dream, had pictured with mischie- vous accuracy, the lineaments of a bc»dy prepared for interment."' Now, many would have put their head under the clothes from fear, and the following day related, with every semblance of truth, that they had seen the corpse of the pedlar. The power of the clouds in reflecting images, and the beautiful and wonderful phenomena of the mirage, oidy remained to be made intelligible to explain many apparitions which were supposed to be supernatu- ral. The Ilartz mountain has been robbed of its mystic wonders. It is })robal)le that the cross which Constantino saw in the air was also some imajjfe reflected from the clouds. Tliese belono; to substantial physical delusions ; for clouds, in the scale of matter. 94 VISION. are very dense bodies compared with gases. Matter is not always gross enough to be visible. It is more in harmony Avith our present subject, to trace the causes of illusions in disturbed states of the nervous powers, to which these physical realities serve as introductory prefaces. " That forms of objects, which have no external prototypes, are exhibited to the mind in certain states of the brain," is advanced by Dr Ferriar ; and we need not quote the instances which he brings forward, having mentioned the case of our friend who was haunted by the spectre dog. " Vriien the brain is partially irritated, the patient fancies he sees animals crowd into his room. These inijiressions take place even while he is convinced of their fallacy." This was precisely the case in that instance. The person knew that no dog was in the room, and yet he got out of bed to verify it. There is something very expressive in the state- ment of Cullen, that the body may be in any state of waking. It may be equally said of the mind, which may be in every state of soundness, from the slightest aberration to complete insanity; or in any state of sleep, from restless dreaming to perfect unconscious- ness. There is a leaking dream ; and there is no better definition for a state of mind which occurs when the ])hysical man is wide awake, and Avhen the system is performing all its functions.. This state implies every degree of disturbed sensorium. The recollection of images in this state converts them into real forms, and gives them a local habitation and a name, — sup- poses them the faculty of speech. It is no imposture. VISION. 95 but self-deception, arising from physical causes ; all the faculties of the sensorium not being fully awake, and still sufficient rational power existing to perforin the common offices of life. In the following, where we acknowledge physical causes, we trace nervous derangement very clearly : " Sauvage mentions, that a woman subject to epi- lepsy saw, during the paroxysm, dreadful spectres, and that real objects appeared magnified to an extra- ordinaiy degree ; a fly seemed as large as a fowl, and a fowl appeared equal in size to an ox. In coloured objects green predominated with her, a curious fact, which I have seen verified in other convulsive diseases. A very intelligent boy, who Avas under my care for convulsions of the voluntary muscles, when he looked at some large caricatures glaringly coloured with red and yellow, insisted that they were covered with green, till his paroxysm abated, during which his in- tellects had not been at all affiscted." The impression was too strong for him to discredit Avhat is styled the evidence of his senses, and yet such evidence often proves very equivocal, as we find that we cannot always trust to one sense exclusively ; that one corrects the other; and it may happen that all the five senses may mislead, if the sensorium coinmnnc, or common sense, be impaired. We find tliat all and each of the five senses do, under certain circumstances, communicate wrong impressions to the brain ; and this may arise in various ways from l)hysical obstruction in the part or in the whole. A\'hcn a man, having taken poison with the intent to kill himself has failed, and is tormented afterwards by 96 -s'lsiON. ociilar spectres, apparitions, &c., we think there is notliing so astonishing in it ; we refer it to a morbid condition of the brain ; words stand for ideas, with- out knowing at all what that condition is. But when in apparent health, and no known cause has inter- vened, then we are lost in Avonder and astonishment, and cannot account for it. Now, we know that pas- sions and affections of the mind are just as capable of producing diseased states of the brain as physical causes ; and by Avhatever means they operate, either by too much pressure upon one part, or by exhaus- tion of another, the nervous equilibrium is lost. We cannot, by thinking it is true, add a cubit to our stature, but we can very easily raise up a giant before us ; and that which is invisible to others, is as real to us as if present in body corporal. " From recalling images by art of memory, the transition is direct to behold- ing spectral objects." If we can so readily account for this whei'e we recognize physical causes, why seek for other interpretations, where, if we do not directly see the cause, we judge, from function, that some must exist ? Once let the imagination be wrought upon, and all the rest will follow. Those who see figures and apparitions will easily be convinced that they hear them speak, and will put Avords into their mouths, Avhich Avill be reflected back to themselves ; and thus divination is, in many cases, to be accounted for ; — so much also for proijhecy. It is wrong to treat all such as impostors ; they really are not so ; if they deceive others, it is because they are too often deceived themselves. But it is still more strange, that others ascribe powers to them wliich they do VISION. 97 not claim themselves ; and it is by adulation and wor- ship that they are made to believe themselves to be what others tell them they are. It is not difficult for a man to repeat a story till he believes him- self to be the hero of the very tale which he has borrowed from another ; and so may the reveries of a disordered sensorium be received with such atten- tion and veneration as to be recognized as prophecy,* and the body physical, from which they spring, be canonized on earth. It is not difficult to prove the truths of such inspiration. We mark when we hit, as Lord Bacon has observed, but not when we miss. This is the history of all second sight and presenti- ments, Avhich latter I have myself often watched and recorded. The fidfilment of one shall produce more faith in their reality than the failui'e of a thovisand. The same holds good in regard to the singular coin- cidences which are perpetually occurring in common life, of people being admonished of the death of their friends by noises in the night, by dreams, and even by seeingthem at noon-day, of Avhich I remember a remark- able case when I was at Dieppe in 1826. A young woman said she saw her brother in the room where others were present, and spoke to him, to the astonish- ment of all. She could not be convinced but that he was there for some time ; — by the next post she heard of his death. If these cases be scrutinized, it will be found that the same people have had the same presentiments many times in their lives, and have never seen them fulfilled. As to the ocular demon- * Here only is the <iuestion of deluded people who have believed themselves so gifted. F 98 VISION. stration, it proves nothing in the last-mentioned case ; because, upon cpaestioning the lady about her brother's appearance, she described his dress, which differed in nothing from that of other men. Noav, though the time at which the form appeared, and that of his death, tallied, there is still this inconsistency, — he died un- dressed in his bed. Dr Ferriar's is now an old book, but it is a very good one, — the work of a gentleman, a scholar, — a physician of the olden time. His analysis of characters, as those of Hamlet and Don Quixote, is quite original.* " There are beauties in the character of Don Quixote which can only be understood by persons accustomed to lunatics. The dexterity and readiness with which he reconciles all events with the way- ward system which he has adopted, — his obstinacy in retaining and defending false impressions, and the lights of natural sagacity and cultivated eloquence which break frequently through the cloud that dims his understanding, are managed with consummate knowledge of partial insanity, though it is sometimes hardly perceptible to the general reader." The physical condition of the optic nerve must not be lost sight of in these observations, which are of more general application. The subject of muscce voli- tantes has been lately much elucidated by the experi- ments of a gentleman upon himself. It was intro- duced by Dr Budd of Bristol, in his Ketrospective View of Physiology, delivered at Northampton on the twelftli anniversary of the Provincial Medical and Surgical Association. * Theory of Apparitions, p. 112. HEAEING. 99 HEARING. The auditory nerve is liable to very disordered states, arising from mental affections. Nervous deaf- ness is a complaint to which many are liable. It is, however, probable, that the labom^s of Mr Toynbee will throw much new light upon this subject, as his examination of the tympanum tends to establish the fact, that many of these cases are due to disease of its structure, and to modifications of inflammation of this membrane. The influence of the mind upon the sense of hear- ing is very considerable ; hence the term listening, which implies a voluntary act, and direction of the mind to the sound, which is not specially recognized but by this act. Thus, when we are asked if we heard what was said, we often reply, — No, we were not listening ; yet half the force of the voice would have been heard by us if the mind had been directed to it. Falstaff would not allow that he was deaf, but said " it was the disorder of not listening, — of not mark- ing, that he was troubled withall." So that many sounds perfectly audible, when the mind is awake to them, are not so when it is absent. On the other hand, a sound may remain in the ear long after all impression, as far as pliysical means are concerned, has ceased ; but it is kept up by the nerves. An expression exemplifying which is, " That same noise is still buzzing in my ears."* It may be the clacking * It is proljablc that this was very instrumental in causing Martin to 100 HEARING. of the wheels of a mill, or the uoisc of a falling ham- mer, or the screaming of a ballad-singer, the impres- sion lasts long after the impressing cause is removed. Of double vision I have afforded illustrations, — of double hearing I know of none, though Muller asserts that it is possible. The circumstance of deaf people hearing common tones of voice when a stun- ins: noise is created near them, is of ordinarv occur- rence. The deafest hear what is said in a low voice, when rattling over the pavement in a carriage; whereas those who hear well on common occasions do not do so under these circumstances. Neither the physiology nor pathology of the ear is so thoroughly understood, but that much still remains unsatisfactory both in regard to the knowledge of the relative powers of the different parts of this minute and very complicated structure, and the remedial means of deafness or of morbid susceptibilities of the impression of sound. I kncAv an instance of most painfully acute hearing towards the fatal termination of a very protracted illness. A young woman of twenty-five died from chronic stricture of the intestines, and for the last three or four weeks suffered most acutely from this affection. It was almost incredible fi'om what long- distances she could hear the least rustling of her nurse's clothes. The slightest sound, not to say noise, was like an electric shock passing through her ears. This w'as more painful to her than all her other suffei'ings. set fire to York Minster. He was evidently in a morbid nervous con- dition, and influenced by fanatical zeal to do some great work worthy of canonization, he 'was kept in continual remembrance of his vow by this buzzing of the organ of which he so much complained. SMELL AND TASTE. 101 Dr Good mentions the case of a young lady in whom this moi'bid state sympathized with vision. " A noise affects my eyes so much, that I am obliged to dai'ken my room when at any time I am under the necessity of hearing any thing like a voice. A loud sound aftects my eyes, and a strong light my ears. They seem to act recii)rocally." — Good's Stiuhj of Medicine. SMELL AND TASTE. There is a certain relation between these two func- tions. Taste may exist without smell, but flavour does not. If the nerves which supply the mucous membrane of the nose have been destroyed, the latter faculty is lost. In states of catarrh, we commonly say that we can neither taste nor smell, and in this instance the olfactory nerves may be supposed to be much more influenced by the morbid condition of the membrane than the gustatory. These two senses offer a wide field of inquiiy for such as diligently prosecute inquiries into the powers of the nervous functions ; all rests here upon impressions made upon nervous papillie, and the communication of these to the sensorium by larger trunks. Idiosyncrasies play a distinguished part in this comedy. The aversion of some persons to the taste and smell of different objects is not imaginary but real. It is not to be dis- guised. The late Lord Selkirk told me that one of the most robust and indefatigable of the North-west Con)pany's agents could not sit in the room if salmon 102 SMELL Al^B TASTE. Avere upon tlie table. He had been known to faint under such circumstances. " Die of a rose in aro- matic pain," expresses sufficiently the effi^cts of such aroma upon the nervous system. A near relative of my own, a medical man, evinced in his own person the truth of morbid susceptibility of the olfactories to the scent of flowers. He was a pious man, and I have known him almost faint in church, and often complain of severe headache for the rest of the day after sitting out the service in summer-time, when the neighbouring pews have been garnished Avith bouquets. A lady arriving in the evening at a country-house, was immediately seized with unplea- sant and uncomfortable feelings, as she sat with the family upon the lawn. She said that it would be considered ludicrous, but she felt persuaded that a hare must be nigh, and that the smell of that animal always made her ill. The shrubberies and lawn were scoured, but none could be found. She still persisted in the assertion, and remained faint and languid. Upon further search, a basket of game containing a hare was found in the larder. In disordered states of the system, the sense of smell is impaired, and, in severer conditions of disease, lost. Its return is not a proof of approaching convalescence, but of the progress to complete recovery. I recollect attending a gentleman who had been convalescent for some time ; but who could not shake oiF, as he styled it, all his uncomfortable feelings. He ate, drank, and slept, but still was not well, a state of things which I have observed to prevail in northern lati- tudes. One day he said to me, I shall do now. SMELL AND TASTE. 103 doctor, for I can come to my snufF again. It was the crisis to the remains of his disease. The hay asthma affords a very good instance of the peculiar susceptibilty of the nerves of the Schnei- derian membrane to the impression of the pollen of flowers floating in the air. A botanist told me it was caused by one species of grass, and by that only, when cut and dried; but the following case proves the contrary : — A gentleman residing in the south of England was annually troubled with this affection to a tiresome degree, and finding that nothing relieved him but avoiding the causes, he migrated to the sea- side at this period of the year. lie avoided going into the fields, and confined his walks to the sea- shore. Upon one occasion, when he had congratu- lated himself upon defying the enemy, he began to sneeze very violently, and was unable to ascertain the cause, till he discovered a solitary black thorn in full blossom. He discontinued his walks till the flower- ing was over, or at least kept to windward of the shrub. I have noticed the case of a relative who Avas mor- bidly aftected by the smell of flowers. It is singular that his mother was occasionally annoyed by a salt taste. She was a healthy old lady, who lived to eighty, and was subject to slight attacks of gout in her hand. These attacks were generally preceded by a saline taste in her mouth. So strong was this, that she could eat eggs Avithout salt. When the gout was fully formed in her hand, her natural taste returned. Some complain that every thing tastes sweet to 104 SMELL AND TASTE. them ; but all unnatural tastes, and the mouth being out of taste, which is a very forcible expression, imply a morbid condition of the sensitive papilloe of the nerves. I knew a gentleman engaged in commercial concerns, whose mouth was out of taste for many months. He consulted several medical men, with no rehef; and as he was otherwise in good health, his friends laughed at him, but that made him no better. His nervous system was, during this time, much influ- enced by the state of his affairs ; for the sudden death of his predecessor had left him a deal to wind up, and he was very anxious to establish himself in the business. In this state he was obliged to go to England, where, having found every thing to his satisfaction, his taste came round again. There is a certain relation between taste and smell, and the simultaneous mixture of the two adds to the pleasure or disgust of certain liquids. The aroma of the fine wines is twice tasted by the gourmet, who applies the glass to his nose before he drinks the contents. The child is told to hold his nose tight before he swallows his senna tea. The sense of taste is improved by cultivation, yet is lost by long use. Hence it is said of French artists, after a certain time, II ne vaut plus rien ; son gout est trop use, il a perdu son gout. It is the cook's taste which regulates the culinary laboratory. Some maintain that substances excite a different taste as they are applied to different parts of the papillae of the tongue. The term arrier gout of the French, certainly seems to express this forcibly, and to justify the idea of a TOUCH. 105 physical cause, for some things which taste very plea- santly in the first moment leave an unpleasant taste behind. The sense of taste leaves its impression long after the substance which excited it has ceased to act upon the nerve, and this interferes with other substances afterwards applied to the tongue. If different kinds of food or wines are presented to a person whose eyes are covered, it is difficult for him to distinguish one from another. TOUCH. We have to say a few words only upon the sense of Touch, to prove (what cannot be disputed) that, as regards the five senses, and their nerves, there is not much real difi^erence in the meaning of the terms. That the senses depend upon the integrity of the nerves for their perfection, is demonstrated by evi- dence so conclusive, that more time need not be occupied in repetition. The effects of a cold, which sheathes their sentient extremities from the impression of matters impinging upon them, or even arrests undulations, rob us of three out of the five senses at once, and leave nothing but siirht and touch to connect us with the external world. The nervous papilla of the tongue, which are con- cerned in the sense of taste, may be rendered more sensitive of impression by use and education ; and those distributed to the ends of the fingers may, by 106 TOUCH. the same means, render touch infinitely more exquisite. There is a certain degree of idiosyncrasy in this sense, as tickling implies, which to some is a most painful operation. Why the nerves of the soles of the feet should be more alive to it is not easily explained. It is a privilege Avhich Shylock claims for the Jew as for the Gentile. There is, I believe, a great deal to be done, in a medical sense, by mere rubbing, if well performed. In many instances, it is the best means of soothing, and induces sleep as sure as an opiate. In many female obstructions, constant rubbing with the flesh-brush will do more than steel and myrrh pills ; but this must not be trusted to the patient, for then it is never done effectually, either from forgetful- ness, fatigue, or the intervention of a hundred other causes. A steady old nurse should perform this opera- tion. In the mesenteric affections of children, the same system is most efficacious. In chronic dlarrha?a I have found it most beneficial ; and in that half and half kind of gout which sometimes makes its appear- ance, and threatens worse attacks for the future, this will often effect Avonders. When I was at Dieppe in 1826, a case of tliis kind occuiTed to me. A captain in the navy was laid up with a swelled ancle, and was unable to walk. Not being in good health, he was in the constant habit of taking medicine. There was not much pain or redness in the limb. After taking some cooling medicine, the local inflammation soon subsided, but the ancle re- mained stiff and swollen He had been subject to the same thing before. I recommended him to rub it nl^ht and morninor TOUCH. 107 for half an hour. Not satisfied with his manipulations, I begged him to employ a fish woman to rub it for him ; and this was done regularly for a fortnight, after which period it was discontinued, the ancle being reduced to its usual dimensions. He had no return of his complaint for years, — I believe, never since ; and, moreover, he left off all medicine, by which his general health was much improved. Rubbing is a soothing, pleasurable, sensation, in many cases, and the whole system sympathizes with it ; tlierefore, time is gained in more general aiFection« ; and, if long continued, it may afford time for the secre- tions to become more natural by degrees. It is un- fortunately of too simple a character to gain much faith, and yet it is a stronger dose than anything ever exhibited from a homoeopathic laboratory. A gentleman complained to me, that he had had an attack of the common cholera some months pre- viously, and that his bowels had since been in so disordered a state as to interfere with his pursuits, tlms being a source of great annoyance to him, and rendering him irritable. I told him to buy a flesh brush, or a pair of hair gloves, and rub himself night and moniing. He told me, some weeks afterwai'ds, that he had found the greatest benefit from the rubbing system. It is questionable if the hair shirt of catholic penance mio-ht not l)c useful in some of these chronic cases of diarrhoea. In some states of disordered nervous functions the nerves of touch get out of order also. Bodies do not make the same impressions u})on them as heretofore. 108 TOUCH. and that which, under most circumstances, is most delightful, becomes unpleasant in morbid conditions of the system : — " A gentleman deeply in love, but labouring inider a neuralgic fever, received no plea- sure from the gTasp of his betrothed's hand, but even a sense of disgust." This is instanced by Dr Macculloch as one of the consequences of that morbid state when every sense is found to be affected. As applied to the skin, the sensations of heat and cold, to which hypochondriacs are subject, even when the thermometer indicates no change in external tem- perature, can be referred only, as Midler has observed, to change in the condition of the nerves. In some cases, heat and cold render precisely the same sen- sation. To a blindfolded man, a red-hot ball, or one of frozen mercury, would produce the same degree of pain. It has been before observed, that perceptive sensa- tion is in the brain. The direction of the sensorium is necessary to the perception of an impression, as before instanced with respect to hearing, and an im- pression is either gi*eatly increased, or may be wholly obliterated, as the mind is directed to or from it. Dr Holland has made some interesting observations on the effects of mental attention on bodily organs, or the direction of the mind to any one point. I shall only extract the following note : — " It may be reasonable to refer to the same prin- ciple some of the alleged facts in homoeopathy, espe- cially the long train of symptoms catalogued as proceeding from infinite small quantity of matters, which are inert or insignificant in other manner of use. TOUCH, 109 The attention, urged to seek for sensations, has no difficulty in finding them. They generate one another, and are often actually excited by expectation of their occurrence." — P. 68, Medical Notes and Reflections. A circumstance in illustration of this came to my knowledge soon after I had read Dr Holland's in- teresting publication. I was mentioning it to a medical friend, who was much struck with the fact. " This," says he, " is in precise confirmation of what has occurred with . He has been attended by Dr , a Homocopathist, who gave him some powders to take, and told him that he would probably spit blood in so many days after he commenced their use. He begged that this might not alarm him, for it would prove critical to his disorder. It did annoy him, how- ever, and his mind was pre-occupied with the idea during the whole of the interval, and on the day spe- cified he did spit blood in the morning. This raised the system of Homoeopathy to the standard of evan- gelical truth — in his mind." Of the truth of this position, Dr Holland has instanced many examples. It is questionable if some of those neuralgic affec- tions, which have their diurnal paroxysms, are not long kept up by the mind being habitually directed to them, and to the hour of their arrival. jNIany must have heard some such observations as the following from patients so affected ? — " The palpitation — the spasm, did not occur yesterday at its usual time ; for, to tell you the truth, I was so very much occupied with a pressing affair that I had not time to think of it." An increased current of the blood, or increased momentum, as Dr Parry observes, as noticed in 110 TOUCH. Tinnitus Aurium, will excite periodical sensations in the organs of sense ; but these will occur without any mechanical causes, and from nervous irritation only. Persons complain of a periodical ticking in the ears ; and the influence of the mind alone will excite all the pleasurable and disagreeable sensations to which the senses are liable. Thus a whole company may be made squeamish on board a vessel, by the example of one individual who is sea-sick, and the thoughts alone of tickling will cause laughter. I question if some nervous affections are not made periodical by the influence of the mind alone. It occurs to some to have what they style a good and a bad day ; and impressed fully with the idea of having an intermittent disorder, they create it afterwards by looking for the bad day. I have known some so very well on the good day as to guarantee them against the bad one, if the mind had not been so prepossessed ; and it has happened that something of extraordinary interest has occasionally caused the bad day to be overlooked, and, by thus breaking the periodic cha- racter of the complaint, has restored the patient at once to health. In the treatment of such cases it would be well, where change of air, &c., are recommended, to make the patient occupy himself with the preparations for his journey on the bad day. This would perhaps convert the bad into a good one, and the following day being the good one, two good days would come together, and this would at once relieve the mind from the spell of periodical disease, which, with the idea of the change of air, might at once effect a cure. THE VOCAL ORGANS. Ill THE VOCAL ORGANS. If it be allowed that the inner man is made manifest in the outer, through the medium of nerves, we must also contend for the exercise of their influence on the organs of utterance. To be struck dumb by fear, by joy, or by any mental emotion, is a phrase of common acceptation, founded on daily experience ; but be- tween this annihilation of the voice and the various modifications of its tones, as influenced by nervous energy, there is every degree of variety. The " vox faucibus haesif^ implies the eflfects of fear in a greater or less degree, which prevent distinct utterance, as long as the moral cause remains unconquered. " The virginity of oratory" is often embarrassed, and even old and hackneyed debaters, under particular circum- stances, experience a difficulty of enunciation at the outset, which wears away by degrees as they warm with their subject, till finally the powers of rhetoric assume their sway, and the will triumphs over all impediments. In his satirical criticism of oratory, Goethe has observed — " Und wenn's eueh ernst ist was zu sager Ist's nosthig Worten naclizujagen Still this embarrassment exists as long as a certain power controls the will; and when we observe speakers in this situation, we say that they are nervous ; and, moreover, we are often made very nervous ourselves by their hesitation. Some sing well in private who cannot face an 112 THE VOCAL ORGANS. orchestra. The fear of the many robs them of that confidence which the few inspire. Others require all the stimulus which crowded benches afford them ; they gain confidence where othei's lose it ; such can- not sing in private. The act of inviting renders some mute, who will sing of their own accord till we wish them dumb. " Injussi nunquam desistunt." The larynx is recognized as the seat of the voice in man, and the inferior larynx in birds. Sounds are also formed in the mouth. If an aperture be made in the trachea below the glottis, which contains the vocal chords, the voice becomes extinct, as long as the aperture remains open. Operations performed upon the human subject for the extraction of swallowed coins, or to prevent suffocation from the closing of the air passages in disease, have established this fiict beyond all con- troversy. If the nerves supplying the apparatus that regulates the conditions of the vocal chords be injured, the voice becomes indistinct ; if the recun-ent nerves be divided, it is altogether extinct. Thus, physically and mentally, we have proofs of the operation of nervous influence over this function. Speech is considered as man's prerogative. There is a line to be drawn between speech and language ; for all animals possess the latter. The peculiar shriek of the hen tells her chickens that the hawk is hovering over them, but this does not imply all the rationality of speech. It is when speech is swamped in lan- guage that we say, He talks like a parrot, or chatters THE VOCAL ORGANS. 113 like a monkey, iclio does not talk, as Dodart observes, solely because he has nothing to say. Dr Elliotson, upon the authority of Locke, who had it from Prince Maurice, instances a parrot, who not only pronounced words, but held a rational conversation. Of this sin- gular exception it may be said, as of some few things of the same nature, that we can only account for it by doubting the fact. If it were true, and speech were proved not to be man's sole prerogative, it would add a sting to Beaumarchais' satire on our species : — " Boire sans soif et faire Tamour en tout temps, il n'y a que cela, monsieur, qui nous distingue des autres betes." Speech is under the immediate control of the volun- tary muscles, which may be so influenced by nervous power, as to correct the impediments to which some are liable. Under the influence of mental excitement stammerers will speak most fluently, but it requires a strong dose for this purpose. If we attempt to help them with Avords, Ave only embarrass them, and render them more nervous by making them conscious of their impediment. If Arnott's opinion be correct, that this depends upon spasm of the glottis, then Diefenbach's barbarous operation was wrong on prin- ciple, when he divided the nerves of the tongue. In exercising this piece of cruelty, he actually excised the organ in one poor boy, who died of hemorrhagy. The defect has been overcome by long perseverance in the exercise of the voluntary muscles. I knew a young lady who Avas cured by reading aloud eight hours dally; but upon relaxing in her practice she relapsed into her former state. The circumstance that 114 THE VOCAL ORGANS. stammerers can sing more readily than speak,* either invalidates Arnott's opinion, or proves the triumph of the nervous power in the greater effort which is re- quisite to perform this function. The decay of the voice is in direct ratio Avith that of the nervous energy. The vocal chords get un- strung, as we find in some nervous affections, and the tone of the voice changes with time, as exemplified in the seven ages : — " And his big manly voice Turning again toward cliildish treble, pipes And whistles in his sound." The impression of cold air has considerable influ- ence upon the voice. The Italian female singers complain of the cold of St Petersburg injuring their vocal powers in the winter season ; and we send aspirants to the south in early life to ripen the voice. Nightingales do not inhabit cold regions, and per- haps they would not sing as they do in the south if they did. Whether birds confabulate or no, Rousseau must determine; but that their song is given them as a compensation for language cannot be doubted, and with some for a specific purpose. It is during the time of incubation that the male nightingale sits on the bough and charms his partner with his song. When the eggs are hatched, the mother regains her liberty, and requires nothing more to amuse her than * I know a singular instance (which in fact came under my own ob- servation) of a gentleman who could not speak two words consecutively without the greatest pain, apparently to himself, and assuredly to those present, giving a most beautiful imitation of John Kemble's delivery of Hamlet's Soliloquy. THE VOCAL ORGANS. 115 tlie care of her brood. The male not only ceases to sing, but he loses his sweet notes and croaks like a frog. Here then the nervous system is in full force. This is a beautiful insight into the bounty of the All- wise in providing enjoyments for the minutest of his creatures. It is not only existence which he has given, but the means of enjoying it to the fullest extent. Those who maintain the ascetic doctrines, that life is a bill of pains and penalties, must in vain look for justification of such ideas in the manifest intentions of Providence. Those who construe good into evil are more morally cruel than the durus orator : — Qualis populea moerens Philomela sub umbra Amissos queritur fcEtus, quos durus arator, Observans nido implumes detraxit ; at ilia Flet noetem ramoque sedens miserabile carmen. Integral et moestis late loca questibus implet. Virij. Geo. iv. I met with a complete case of ajihonia in a Russian general, who returned invalided from the siege of Varna. His voice was perfectly extinct. He remained some time at Odessa, and received no benefit from anything that was tried to restore it. I gave him Ijark, ammonia, and valerian. He w^as a very nerv- ous man. The Emperor desired him to return to St Petersburg. Upon his route to Moscow he sud- denly recovered his voice in an instant, and did not lose it again for years afterwards, as I had an oppor- tunity of knowing; but he was a martyr to other nervous aflfections. A circumstance in his case is worthy of note ; soon after his return to St Peters- burg, and not long after he regained his vocal powers, lie was affected with a painful induration of the sper- 116 THE VOCAL OEGANS. niatie chord, which troubled him for some time. As I did not treat him for it, I do not know what mea- sm-es were employed. It made the more impression upon me at the time, as Dr Macculloch mentions a neuralgic affection of the testicle ; and the sympathy which exists between these parts in early life made it still more impressive. INFLUENCE OF BLOOD UPON NEEVES. 117 PART vr. Influence of Blood upon Nerves — Nervous Complaints — Headaches. INFLUENCE OF BLOOD UPON NERVES. "When Gil Bias told tlie bishop that his sermon smelt of the apoplexy, he proved himself more conversant with the animal economy than his master, Sangrado. The practice of the latter is most justifiable in this affection, but the removal of the offending agent does not remove the injury •which it has perpetrated ; nor is it from post mortein examinations that we can always judge of the nature of these injuries. In the Appendix v,\\\ be found a case of what the Germans style Xevven Schlag, where the appearances w^ere not suf- ficient to warrant the sudden death of the patient. The brain may receive a shock, or be injured by noxious matter, so that the nervous system shall be completely paralyzed Avithout any organic lesion being demonstrable, as before observed, e. g. in such morbid states of the kidney as prevent them from performing their purifying offices. Here the blood becomes the direct cause of offence, as certainly as when it conveys adventitious matter introduced into it by way of experiment. In saying that no lesions exist, it can only be understood that none arc found, rccogniz- 118 INFLUENCE OF BLOOD UPON NERVES. able by our senses. The blood may be the cause of injury to the brain, either from morbid constitution, or abnormal circulation, for Avhich the brain may in some cases have to thank itself; for physical effects arise from moral causes. That the blood has great influence in the production of a numerous class of diseases which are generally denominated nervous, cannot be denied ; but the question remains to be solved, what the nature of its influence really is ? Are we to look for it in a change of the condition of the fluid itself, or to change in its impetus and momentum, or, in many cases, to a com- bination of the two causes ? It is perhaps going too far to adopt all the views of the late Dr Parry upon this subject, but that there is a mass of evidence in his favour, in very many instances, is highly probable. In the mechanical views, which he takes of the causes of many diseases, there is much more probability of truth, than in attributing these to chemical changes in the blood itself. If inquiry be made as to the causes productive of the disturbed balance in the circulation, they must often, in the first instance, be referred immediately to derangement of the nervous system. Epilepsy offers a good illustration, for it is fre- quently produced by some irritation of a local nature, w^hich throws the nervous system into convulsions by indirect action through the sanguiferous system ; and it is more probable that the epileptic fit, Avhich ushers in some of tlie exanthemata, is rather due to deranged balance of circulation than to morbific matter in the blood. Dr Parry observes — " Epilepsy is also most apt INFLrENCE OF BLOOD UFOX NERVES. 119 to affect young persons, who are well known to be most liable to diseases accompanying the nervous tempera- ment, and of these, more especially females, who have not yet reached the period of fully established men- struation. " At a more advanced age, it chiefly attacks those who have long been constitutionally nervous, or who have lost the accustomed excessive sanguineous de- terminations of gout, hemorrhages from the nose, hemon-hoids, ulcers, eruptions, &c., and in all these cases the pulse in the carotids is habitually stronger than natural. It is often one modification of that increased determination to the head which attends dentition, and not rarely comes on in that stage of the cold fit of agues, and before the eruption in certain other fevers, when the blood is accumulated about the heart and large vessels. I have seen it form one link in the chain of excessive determinations following scarlatina, of which articular inflammation, hemorr- hasre from the kidnevs, and anasarca, constituted the preceding links. " It frequently follows hysteria or mania, or alter- nates with them. In several instances I have known, in the same patient, paroxysms occur at different times in all the intermediate degrees between common hysteria and the severest epilepsy. Lastly, it often terminates in or is exchanged for sanguineous or serous extravasation in the brain, and consequent liemiplegia or apoplexy, whether hemiplegic or otherwise." These observations only tend to prove that existing causes, which increase tlie determination of blood to the brain, or the force witli which the blood is [)ro.T 120 INFLUENCE OF BLOOD UPON NERVES. jielled, produce such an impi-ession upon the cerebrum, ah'eady predisposed, and in a previously irritable condition, as to excite the convulsions of epilepsy. A sudden passion or emotion of the mind, and, indeed, all those causes which influence the heart's action, beinsf able to effect this, it is evident that it is not the quality but the quantity of the blood, which is in fault. And the same applies to many cases of simple fever, which are kept up by irritation of the brain, from increased determination, rather than from any dele- terious quality of the fluid itself; because we often see an attack of fever cut off at once by a judicious bleeding. It is well known that the quantity of blood, which is no more than requisite to health, may be super- abundant in disease ; and the same argument may be applied to its momentum, just as the weak eye cannot bear the light, neither can the irritable brain support the influence of the same quantity of blood as in its normal state. The symptoms arising from this state of the circulation, as headache, throbbing noise in the ears, sleeplessness, have all been suspended by mecha- nical causes interrupting the floAv of blood to the head, as by pressure of the carotid arteries ; and a sudden hemorrhagy or loss of blood will, as Dr Parry observes, sometimes cure a long existing and intractable disease. I had an opportunity of witnessing this in a patient of my own, a young man of delicate constitution, w^ho had l3een long troubled with severe headaches, which interrupted his course of studies. His horse having run away with him, and fallen at full speed, threw him with o-reat violence against a gate post. He was taken up INFLUENCE OF BLOOD UPON NERVES. 121 insensible, and I was sent for; as some hours had elapsed before I arrived, a practitioner in the neigh- bourhood had been called in, who bled him from the arm and applied leeches, one of which biting a branch of the temporal artery, caused a considerable loss of blood. He remained from the Friday to the Sunday evening speechless, when, opening his eyes, he said, " Put the horse in the stable." This was the point to which the mind returned after forty-eight hours oblivion. He recovered eventually ; and, since this accident, has had no return of his headaches. The idea is too prevalent, that nervous diseases must be all attributed to a weak condition of the nerves, and that bark, and wine, and valerian, are the agents which are alone applicable to the cure of such. This is as absurd as to suppose that all fevers spring from a vitiated state of blood. If many of these complaints are relievable by abstracting the causes which excite them, are they the less nervous on that account ? The nerves are as liable to im- jiression from the circulation, as the bones or muscles, and they are subject to every degree of irritation. The only difference is this, that they often generate their own diseases. It is, therefore, a matter of great importance and nicety to determine, not what is the nature of the disease, but what causes it ; and he who resorts to stimulants for all nervous affec- tions, must find himself often thwarted in his plans of relief. The terms nervous, and nervousness, are too sweep- ing, inasmuch as by such is generally implied a certain modm medendl, which is often most inapplicable. Dr G 122 INFLUENCE OF BLOOD UPON NERVES. Wilson has made some very valuable observations on this head. The referring of deafness to this cause has proved a a:reat stumblino-block hitherto in the treatment of that malady. It is often the deafness which makes people nervous, and not nervousness which causes deafness ; and hence the opportunity is often let slip of alleviating this complaint. It is nervous in the strictest sense, for when inflammation is set up in the membrane of the tympanum, the nerves are immedi- ately acted upon, and the impression is communicated to the sensorium. The irritation of a nervous twig wull produce a host of distressing symptoms, which, though of secondary occurrence, become so predomi- nant, that the primary cause is lost sight of. In this way the delicate membrane becomes disorganized, and, as it occurs generally in one ear only at a time, it is neglected or unheeded, till the same series of symptoms commencing in the sound one, some medical relief is sought for. Mr Toynbee informs me that he frequently does not see patients till they have lost their hearing on one side. " There is a common species of deafness, of which Dr James Sims has spoken, if not first, at least best, in an excellent memoir read before the Medical Society of London. Like many other disorders of circulation, it is usually called nervous. It seems evidently to arise from obstruction in the Eustachian tube; ac- cordingly, when it is simply of this kind, the patient can hear well Avhen the tube is distended by strongly blowing with the nose, — mouth and cheeks closely shut. He can usually, also, at all times hear acute INFLUENCE OF BLOOD UPON NEEVES. 123 sounds, but not the more grave ones. In this case there is so far from being any real paralysis of the nerves, that acute or very loud sounds are even painful; and what demonstrates that this is a disease of in- creased vascular fulness or impetus, and not of nervous insensibility, is, that I have known it, first, removed on the occurrence, in the respective examples of hepatitis and hemiplegia, andreturn as those complaints were diminished ; secondly, entirely cease in two in- stances, forty-eight hours before death ; and thirdly, completely cured for more than a year of the remainder of life, by an accidental hemorrhage from the humoral artery. This species of deafness is very commonly produced by colds in the head, in which it is evidently owing to a communication of disorder from the mouth and nose along the membrane, which is continued into the Eustachian tube. It is probable, however, that, on many occasions of deafness, the malady is not confined to this part ; but it is worthy of inquiry, whether, in such cases, the effect does not originate in a similar excessive impulse of blood acting on some other essential part of the organ of hearing." — Parry's Elements of Pathology, p. 176. The numerous dissections which Mr Toynbee has made of the car, have convinced him that the seat of deafness is almost always confined to the tympanum, and is the result of slow, long-continued congestion in the vessels of the membrane, finally destroying the nerves, and becoming itself opaque. It is generally observed that deaf people are irritable and nervous, and it is not to be wondered at, when, by this malady, they are cut off from the mental 124 INFLUENCE OF BLOOD UPON NERVF^S. world. Did not they too long mistake cause for eft'ect ; and, instead of considering that their deafness arose from nervousness, attribute the latter to the former, they might often prevent the loss of this sense. Here again, we see cause and effect reacting on each other : the irritation, from the local cause, creates general irritability of the nervous system, which again increases the very cause which has produced this state. It is not in this affection alone that we trace the operation of nervous influence, for headache, noise in the ears, dimness of sight, and vertigo, may all be in- duced by mental emotion, or the too strong direction of tlie mental powers to any particular study. The blood may be propelled with too much or too little force to the brain, and equally produce disorders of the nei'vous system. In all these disorders, so styled nervous, consequent upon deranged circulation, it is a question merely cf mechanical influence, and not of vitiated quality ; for so necessary is the healthy state of blood to the well-being of the system, that when it is really altered in quality, we find it productive of the most fiital consequences. It matters not whether the prime cause of offence be in the blood itself, or whether this be brought about by deterioration of nervous influence, the effects are the same. It may become corrupted by degrees, as in cases of fever, and no longer afford the stimulus to tlie nerves which is necessary to life. If the blood be materially altered in its constitution, — if it be charged even with those matters which should have been separated fron^ INFLUENCE OF BLOOD UPON NERVES. 125 it by the secreting organs, or if any cause or impedi- ment prevent their due operation, so that it be not purged of matters which are incompatible with its healthy state, then we see the disastrous consequences, and nowhere better than in those cases of sudden death, proceeding from the suspension of the ui'inary secretion, either in Ischuria Renalis, or in certain morbid conditions of the kidney. In such cases no organic lesion, no effusion, are visible, but the mat- ters contained in the blood are applied to the brain, which thus becomes poisoned. This is efiected not by injury to the blood itself, for of this there is no proof, but by injury to the brain from contact with noxious matter. It is upon this knowledge, therefore, that we may presume that many of the diseases caused by the circulating fluid are rather to be attributed to the mechanical influence of impetus and momentum, in excess or in deficiency, than to any change of quality in the fluid itself. I can only refer to Dr Parry's work for a numerous list of those diseases which he attributes to increased determination of blood. — P. 320. Among these will be found headache, vertigo, sleeplessness, common nervous aflPections, mania, deli- rium, convulsions, hysteria, epilepsy, catalepsy, &c., all of which are not the less nervous, because an ex- citing cause is made evident. It is a very great mistake, too often made, to ne- glect seeking for the real cause of nervous complaints. The term nervousness is sufficient to occuj)y our attention without further examination. It implies generally every thing with which we are really not 126 INFLUENCE OF BLOOD UPON NERVES. acquainted. To believe tliat a patient is only ner- vous is sufficient to stop farther inquiry. lie is then without the pale of rational medicine. Now, there is often as palpable a cause for this state as for any other morbid condition of the system ; and these sweeping clauses bring the profession into disrepute, whilst they allow quacks to triumph. The author of the Bath Guide was hardly too severe upon the profession, when, after the consultation of physicians, the patient is made to say in his letter to his mother — " I'm bilious, I find, and the women are nervous." So it is even in the present day ; and the two com- plaints are associated with valerian and bark, or blue pill and black dose, by which treatment, in many cases, the evils are aggravated tenfold. I have now an op- portunity of knowing, that a gentleman affected to a most uncomfortable degree by nervous deafness, under which he laboured for years, has been perfectly re- stored to hearing by such treatment as was scientifi- cally adapted to chronic inflammation and increased determination of blood to the tympanum. In St Petersburg hemorrhoids prevail to a very great extent. Of this there is often sufficient ocular demonstration ; but they are supposed to exist inter- nally much more frequently than they are found externally, so that if there be the least obscurity attending the state of a patient's disorder, it is attri- buted to hemorrhoids. In my own practice I have known a discharge of pus from the bowels in mesen- teric affection, denominated a hemorrhoidal abscess. The patient died of marasmus. A calculus passing INFLUENCE OF BLOOD UPON NEFtVES. 127 from the kidney to the bladder, and sliding down the ureter by degrees, so as to create the most painful neplu-itic symptoms, at several periods during a jour- ney of ten months, was denominated a hemorrhoidal colic ; but the calculus made its appearance in the urethra and was extracted. This case I published in the Medical Gazette. A valet of the Count , with whom I lived, was long affected with hemorrhoids, till examined by a skilful surgeon, when he was found to have an abscess in the perineum. Spitting of blood is a common hemorrhoidal affec- tion, as are most affections of the eyes not attended by inflammation. The late Mr Tyrrel was consulted by a Russian nobleman for an affection of the eyes, which he was told was hemorrhoidal. He laughed heartily at the idea. This generalization of complaints must give way to the more scientific views of the present day ; but it is not all eradicated ; and if a large class of ailments do come under the definition nervous, which is tanta- mount to confessing our ignorance of their causes and seats, still a great many, upon careful investigation, will be found to depend upon positive affections of the nerves. The great difficulty lies in administering to these affections. We cannot get at an individual nerve but tiirou^h the medium of the circulation, so that the dose we apply to it must be very small, and, at the same time, we are subjecting healthy parts to discipline which they do not require. Even in such cases, as where we can subject an individual nerve to experi- 128 INFLUENCE OF BLOOD UPON NERVES. ment, we often gain nothing by it, for if this nerve have its roots in the brain, it is useless to operate on its twigs. There are cases where the whole nervous system is affected by irritation of a part, as where lancing the gums has arrested the convulsions which often arise from teething. I have known a whitloe attended with pain in the chest and dyspnoea. The pain of toothache drives a person mad, in common phraseo- logy. These are come-at-able nervous affections; but how are we to get at those situated internally, produc- ing distressing effects, and so operating by sympathy upon other parts of the system, as to be lost them- selves in the crowd of other affections to which they give rise. Many of these depend entirely upon abnormal cir- culation, and are attended with jDcriodical paroxysms of pulsation when the system is under the influence of exciting causes. An affection of this kind is some- times met with in the pylorus. A gentleman laboured under a complaint of this kind for many months. It was treated as a nervous affection, to v/hich its perio- dical return lent a degree of probability. It regularly occurred just two hours after his dinner, and continued for several hours. All the anti-nervous medicines Avhich he took tended only to increase it. He sub- mitted to the hunger cure, by which he was per- manently relieved, though he w^as reduced to great debility by the experiment. Here, then, was a case of diseased nerve, and not of nervousness, and a proof that the nerves when affected are not to be treated upon one and the same plan. It was evident INFLUENCE OF BLOOD UPON NERVES. 129 here that the distension of tlie vessels from determi- nation of blood during the digestive process, was tlie cause of the evil ; and, by cutting off this process, or reducing it to no more than was necessary for the mere purposes of life, the nerves were allowed to regain their healthy state. We have pathological proofs of the conversion of insensible into sensitive parts by the influence of dis- ease, as in affections of the serous membranes, which, in health, arc hardly susceptible of pain from injury ; but when once inflammation is set up, they become, by reflex action, most highly sensitive, nor is it till this condition is effected, that inflammation can he said to be fully formed. In the treatment of membranous inflammation, local bleeding is perhaps, in this country, too much ne- glected. On the Continent it is seldom dispensed with. Full bleeding from the arm is accompanied by free applications of leeches to the part affected, and many a repetition of the general bleeding is in this way prevented. In cases of peritoneal inflammation, it is not uncommon for the patient to complain of severe pain after the first bleeding, which is relieved by a second, or still more by the adjunct influence of topical abstraction. A dull heavy pain is converted into an acute lancinating one from partial depiction. The cause is evident ; the larger vessels being re- lieved without the same relief being afforded to the capillaries, the action of the heart has greater power in forcing the blood into them, as the vessels most contiguous to them admit, by being unloaded, of greater distension; so that tlie relative momentum, as 130 INFLUENCE OF BLOOD UPON NERVES- i-egards the capillaries, is greater than before, and hence the nervous expansions are more tortured than previously ; but when the general momentum is di- minished, and the capillaries are allowed to unload themselves by topical abstraction, then the nervous irritation subsides gradually. I may say that I have never seen inflammation otherwise treated on the Con- tinent, but by conjoint use of general and topical blood letting. In many instances free application of leeches su- persedes venesection ; nor can we well account for the relief experienced, which is sometimes immediate. This may be understood where w^e act upon anasta- mosing vessels ; but this is not always the case, for, as John Hunter has observed, there is no connexion between the vessels of the scrotum and testicle, and yet there is no more certain way of relieving that painful affection. Hernia humoralis, than by topical bleeding. This same argument applies probably to some affections of the synovial membranes and cartil- ages of the joints, viz. that all the good is not done which might be done by a continuance of the deplet- ing system. It is not persevered in long enough, nor is the depression suflficiently long maintained to allow the minute vessels to recover. It is a hunger cure which they require ; and the stimulants and rubefa- cients which are employed, sometimes by the external pain which they create, disguise the real state of mis- chief going on beneath. Hence long continued chro- nic inflammation may proceed to disorganization of these parts. A moderate but long continued abstrac- tion of blood would restore them more certainly to HEADACHE. 131 their normal state than one copious abstraction fol- lowed lip by counter irritation. It is here the question, as must be evident, of decided inflammation acting upon the nerves, and not that neuralgic state which often occurs in the knee, and which would be aggravated by such treatment. HEADACHE. It would be one of the most important discoveries in our art, if we could arrive at such a knowledge of the causes of this cruel torment as would enable us to pursue some rational mode of treatment. It is here that we have the most cause to complain that we have very bad eyes ; could we look into the skull, and see what is going on there, we might per- haps arrive at something like rational practice. We have advanced but little in our knowledge of the matter when we are told, that the headache is nervous ; the value of that phrase has been already dis- cussed ; but even when we know, as in these cases, that the organ of the brain is affected, Ave do not know in what precise manner ; hence, nothing is more empi- rical, nothing more unsatisfiictory, than the means adopted for its relief, and, for the most part, unsuc- cessfully. Patients who have suffered long under these affec- tions, and have gone what they style the round of physicians, with little or no benefit, give up all hopes; and to use a phrase of a Russian whom I 132 HEADACHE. treated for this tormenting complaint, — " I must live with it." Lord Byron, who was a martyr to it, used to exclaim, as he placed his hand upon his brow, — " This head of mine was made to ache." It is the nerves which suffer in this, as in the many disorders already instanced, whatever may be the exciting cause. Increased determination of blood to the vessels of the brain is one of the most common, and this may arise from a variety of circumstances. Moral influence plays an important part in these affections, and they are the inheritance of the philo- sopher, the poet, and the statesman. The conse- quence of abnormal circulation in the first instance, they subsequently are the permanent effects of dis- eased organization. The vessels, from continual dis- tension, lose their tone, and chronic inflammation is the result of such injury. Hence these affections get v.'orse and worse, lead to derangement of intellect, or fever is set up in the system, and is of fatal issue. It may be idiopathic from nervous lesion, or the sus- ceptibility of impression being increased by pernicious eflfluvia, find the ground prepared for their reception. This was probably the history of our great bard's fate. These affections are difficult to treat in all their stages ; but they would be remediable, if those who suffered from them would make the same effort to get rid of them that they do to render them permanent. It is the continued dropping of the water that wears away the stone ; the impression is long before it is perceptible, but the basin is hollowed out at last. HEADACHE. 166 Mental excitement, however rapturous, must be fol- lowed by exhaustion ; the materials of which we are composed are evidently not intended for eternal dura- tion. There is a limit to our mortal existence. There is a natural period of decay ; the house may be propi)ed up for a long time, but it will fall at last. In a ratio with the demand made upon it, the energy of the mind will be found to decrease, provided that this demand lead to excitement, and influence organic structure. It is the " restless and unquiet thing" to which we par- ticularly allude, the man of passion and of strong ima- gination, who is exhausted by excitement, morally and physically. Byron and Southey have offered two illus- trations. The men who cannot, or will not, control their passions, — who sacrifice all to mental intoxica- tion. It was so of old times, and it will be ever so. The abstract studies may be pursued with safety, and the mathematician numbers a long series of years. The statesman and bard, — how many reach three- score ? If physical power is exhausted, there is no longer manifestation of moral powers ; they die away, or go out of the right road. I must lean to the opinion, that mental aberration in excitable beings is a con- sequence of a disease which the mind has itself created. It has been lately stated by Mr Bai'low, that the mind may control matter even after disorganization has taken place. Of this there can be no positive proof; and the circumstance of injury to the brain from acci- dents permanently disturbing the mental powers, woidd argue against it ; but it is often Avithin our ])ower to prevent this physical state by controlling mind. It is 134 HEADACHE. not when the man is restless, tossing about on his couch, his hand burning, liis head throbbing under the paroxysm of fever, that we can say to him, " Lie still, — be calm, — go to sleep, and the fever will leave you." It is not till the latter has left hira that he will compose himself; and so it is with the fmictions of the brain ; if these be disturbed by local injury, from whatever cause, and from none more readily than from moral causes acting upon the physical organization, the healthy moral state will not be manifest till the exciting cause be removed. It is in the early stages, therefore, where function only is concerned, and organic deterioration has not taken place, that hopes of alleviation can be justly entertained. It will de- pend, however, even in this extremity, upon the amount of injury done, whether it may not be remedi- able. The membranes of the brain are under the control of medical agents, as are other membranes of the body ; and if all exciting causes can be removed, and they are not sufficiently deranged in structure as to become themselves a permanently exciting cause, so that cause and effect are continually operating to effect injury, the evil is not irremediable. The source of many headaches is to be attributed to that state of excitement, which determines a greater quantity of blood to the brain than it can bear with impunity. Of this there is sufficient evidence on record ; for a sudden loss of blood from accidental causes has liberated those who have suffered for years under such affections. It is not often, however, that medical aid is demanded, till a certain degree of mis- chief is done. People give themselves credit for great HEADACHE. 135 discrimination in these matters ; they distinguish be- tween a sick headache, which is caused bj repletion, and that kind of nervous headache, for which they think there can be no cure if Hoffman's drops are not equal to effect it. The literary man understands the cause of his ailment, but is content to put up with it as long as it is not intolerable ; when it is so, it is too frequently irremediable ; and the expression of such must be familiar to many medical men : — " If you wish to do me any good you must give me a ncAV head, for this one is worn out." The nervous female endures it for years, and is persuaded that there is nothing which can relieve a nervous headache ; and she is confirmed in this opinion by not finding any relief, when she has applied too late for it. I M-ish I could assert that my success in the treat- ment had been in any ratio with my opportunities of beino- conversant with these affections, which are so very prevalent in the north, for reasons already stated. If increased momentum, or determination of blood, be the primary offending cause in many of these cases, it must be remembered also, that the effects which they produce will, after a certain time, generate a condition wliich will be aggravated by means that might, in the first instance, have conquered the enemy. General and local depletion are as unadvised, when a chronic state of inflammation is set up, as stimulants would be at the commencement of the malady. I have, in these so called nervous disorders, which occur periodically in many, and are attended with threatenings of mental aberration, prescribed the shower-bath with the most happy results. A gentle- 136 HEADACHE. man of very irritable temper, and about the middle age of life, liable to be put out by any untoward domestic circumstance, was subject to periodical at- tacks of headache, accompanied by great nervous irritability, and such loss of temper, as to make his state rather alarming to his friends. His health was in other respects very good, his circumstances were easy, and there was no moral cause in apparent ope- ration. I recommended him to try the shower-bath as soon as he quitted his bed ; he felt immediate relief from its use, and afterwards, (for he disconti- nued it when the affection had quite subsided,) when- ever he had the least threatening of an attack, resorted to it, and always with the same success. It is some years since it was prescribed for him, and he has never had a paroxysm, such as he before experienced, since he commenced its employment. A clergyman, subject to periodical attacks of head- ache, accompanied by hypochondriacisra to a great degree, had found the only relief to his paroxysms in this remedy. In a village w'here he was staying, he was attacked by one of his usual paroxysms, and not being able to procure a shower-bath in the house, rode daily to a gentleman's seat in the neighbourhood to benefit by this application. A lady who was subject to constant headache, was greatly relieved by the use of the shower-bath. She was very delicate, had borne many children, and was subject, after each parturition, to uterine hemorrhagy. She had received a blow upon the breast, which caused her great inconvenience, and she experienced periodical attacks of pain and uneasiness at the menstrual period HEADACHE. 137 more particularly. She was so much annoyed by the pain which the cold water caused, as it trickled over the breast, that she was compelled to abandon the use of her bath. Her headaches returning, however, she resorted to her old remedy, and used to cover her chest with an oil-skin cape, which allowed her to continue it as usual, and with the same good effects. I have found it equally beneficial in cases of hemi- crania. On the medical treatment of nervous headaches I have but little to state that is satisfactory. Arsenic is often useful when there is decidedly an intermittent tendency ; from quinine I have experienced less suc- cess, and, where it is used, it should be combined with some purgative, for an open state of the bowels is always a source of relief, although purgatives do but little good if given alone. The medicine which I liave often found useful is Griffith's mixture, combined with a blue pill once or twice a week. \'ery much is to be gained by attention to diet ; and as regards rules upon this matter, it would be well to direct that patients should resist the tempta- tion to take what disagrees with them, and all know that by experience. Upon the point of wine, how- ever, there may be room for discussion, and patients may honestly require advice upon this head ; for many to whom the taste of wine is disagreeable take it medicinally ; some take it too freely, but upon medical recommendation ; for the fiiculty is divided in opinion upon the subject. I have never found it of service in nervous headaches, although these might arise from direct debility, if it produce heat and flush- 138 HEADACHE. ing of the face. The home-brewed bitter malt liquor is preferable in these cases. Having advocated Father Mathews' cause when disease really exists, I Avould reprobate it under other circumstances ; for I hold that a generous diet and the use of wine will often be the best preventatives to disease. If, as I have men- tioned in another place, a change of life from the redundant to the extreme abstemious be sometimes attended by disastrous consequences, so symptoms which were aggravated by a mistaken forbearance fi'om the good things of this world, are wholly relieved by adopting a generous mode of life. This was the case with a relative of my own, who was very subject to low spirits and hypochondriasis. His medical attendant felt his liver so often, with the view of discovering if there were no disease there, that he at last made the patient believe that something was wrong, for the side from touching became sore to the touch. The patient put himself upon a very abstemi- ous plan, lived chiefly upon fish and boiled meat, and being much interested in politics, read Cobbett's Register. He did not improve under such discipline; he was nervous, irritable, subject to headache, and all the train of symptoms which accompany this state. This continued for years, when his attendant per- suaded him to try the Cheltenham waters. Previous to doing this, he resolved on consulting the late Dr Baillie, who, on being asked his opinion as to the patient's going to Cheltenham, replied in the affir- mative ; or, he added, anywhere else where he would best amuse himself. He changed his plan of diet, took wine in moderation, and in a little time was HEADACHE. 139 restored to perfect health, which he has now enjoyed for the last five and twenty years, and for which, I believe, he is wholly indebted to his change of regi- men. Dr Macciilloch has much enlarged upon an ascetic principle, as he styles it, in our natures, a self-denial of thinors which are more beneficial than otherwise when used in moderation. These nervous headaches are more frequent in the female than the male sex, and are often consequent upon exhaustion from rapid child-bearing, periodical evacuations, and a mode of life which society pre- scribes, and to which they must submit. The circu- lation is languid from want of exercise, with which their domestic callings often interfere. Tea is a favourite beverage with them, and there is none more pernicious, particularly if there be any green tea in the infusion. At all events, it should never be taken in the evening. Light cocoa is better for a mornino; beverage than tea. Coffee is less j)ernicious, and a strong cup of it will sometimes dissipate a nervous headache. As to all that can be said as regards social enjoyments, it is as well to be nnite, or to say of them as of regimen, all know how far they can trespass ; and it is not the want of the knowledge of their effects, but the want of courage to resist the temptation, that is the point in question. It is here that homoeopathy triumphs. The practi- tioner of this quackery has every thing in his favour but his medicine. The sensualist, the votary of pleasure, think nothing of the sacrifice which they make when he commands it; but they turn a deaf car 140 HEADACHE. to the entreaties of a regular practitioner. It is not that these affections are cured by homoeopathy, for it is negative for good; but they are avoided by the circumstance of non-exposure to such causes as pro- duce them. Under the term of nervous headaches, may be included such as are the result of exhaustion, which are more or less constant in their attacks. Sometimes enduring for days together, at other times visiting at irregular periods, they are generally confined to the fore part of the head. They may occupy a single point, or one side only. They attack and quit in- stantaneously. I witnessed an attack of this kind in a female, past the middle age of life, who Avas sitting at the tea-table, Avhen she complained of a sudden shot through her head, and felt hardly able to sit upon her chair, from the vertigo which it occasioned. She resorted, as usual, to Hoffman's drops, but without benefit, and the whole of the head ached violently for at least three hours. I begged her to apply a large sinapism to the neck, and this afforded her some relief. As suddenly as the first attack manifested itself, so suddenly she exclaimed that the pain had entirely left one side of the head, but was equally severe on the other. I recommended her to take a dose of laudanum. She retired to rest, and hardly had she got into bed when the headache entirely left her. She did not take the opiate. She has been subject to headaches for years, but said she never w^as attacked so severely or so suddenly before. Upon the pre- sumption of these being the effect of debility, she had been in the habit of drinking a deal of porter. HEADACHE. 141 Wine was hardly at her command. She went into the country, and from some cause gave up malt liquor, and with evident benefit to her health. I saw her afterwards, and prescribed GriflSth's mixture, which was of the greatest service to her, and she has been freer from headaches than for a long period previously. In this case, the digestive system was greatly deranged. She suffered fi'oni dyspepsia, and could only digest mutton, fowl, and game. Fish of all kinds, veal, pork, and every kind of pastry, were as so much poison to her. These headaches, and many more of the same kind, depend upon some state of the nervous system, which is often too obscure to allow us to say what that con- dition is. They are hard to bear ; but hundreds do o'o through life with such inflictions entailed upon them. They are chiefly the inhei'itance of females, who bear suffering more patiently than men, and whose physical lives are sometimes a continued state of pain and penalty. In the rheumatic headache we have something more tangible. If Ave do not succeed in relieving it, we seem to set about the task with more confidence. It is the most painful perhaps of all the kinds, but it is sometimes remediable. It often begins in a point over the eye, or in the temple, and then gains the whole head. A full dose of cotchicum, at the com- mencement, Avill sometimes cut it oftj and with this a dose of calomel and opium at night. A lady whom I treated for this aflfection, was relieved by a mixture of decoction of bark and guaiacum, in e({ual parts, of which she took a dose three times a day. With her 142 HEADACHE. it proved a specific, and she wrote to me for the pre- scription sometime afterwards from Italy, as she had found nothing else relieve her. For that species of headache which commences a day or two before the menstrual period, and continues throughout the same, there is perhaps no means of relief. I have known it attended by the most excru- ciating pain, the patient confined to bed, with the head under the clothes, and almost distracted for the time. There is another kind of headache, the treatment of which our continental brethren understand better than ourselves. It is the hemorrhoidal. It manifests itself by dullness, heaviness, and sense of weight in the head, causing inaptitude to all mental exertion. It is with some almost periodical ; and, for this aflPection, leeches to the fundament are a specific. La tete est degagee, is the expression of all who are thus treated. I have seen the good eflfects of such practice many many times. Of bilious headaches the cause is sufficiently clear to point out the treatment. Resolution to avoid the evil is the desideratum. There is a species of headache to which children are subject, and which is alarming as a sympton which threatens hydrocephalus. Spunging the face, fore- head, and back of the neck with cold vinegar and wat^r, often relieves it. Ice to the head is too strong an application, and perhaps may do mischief, by keeping the whole of the membranes of the brain too full of blood. In these cases, if they are obstinate, and in girls, the Germans put an issue in the arm till the menstrual period is formed. HEADACHE. 143 There is an epispastic much used abroad, which I think Avould be advantageously introduced into British practice. It is the pommade vegetale de Swisse, a preparation of the bark of the mezereon, which, when rubbed on the skin, produces immediate vesication, without causing the same irritation, and never ac- companied by any of the unpleasant symptoms which are sometimes produced by the blistering fly. It is employed generally to produce vesication behind the ears, and particularly in the affection we are speaking of. A small portion, rubbed strongly in, raises a blister in a few hours, and the surface may be made to discharge for any length of time, by smearing it over with the same preparation. Where a large blister of the lytta has been first applied, this prepa- ration answers much better than the savine ointment in keeping it open. I have not been able to procure it in any of the druggist or patent medicine shops in this metropolis. In cases threatening hydrocephalus, the Germans apply it behind the ears, and keep one side in a state of exudation for years consecutively, where they do not insert an issue. Counter irritation is the favourite practice of the German school for a host of disorders. If it do all that is attributed to it, which is saying too much of any preventive measures, (for we must always ask the question, whether such have been really so,) it has a great disadvantage even in this view of the subject. It cannot be permanently employed. People in good health will be disposed to do without it, after a certain period of endurance. Yet there is no affection, of whatever nature it may be, nor at how distant a 144 HEADACHE. period soever it may occur, after the closing of a fon- tenclle, that is not immediately attributed to that unhappy circumstance. In investigating the history of most diseases, it is a leading question, whether some local discharge has not been dried up. It remains to speak of that species of headache which, for the most part, is, I believe, the result of moral influence, and is caused by an increased deter- mination of blood to a brain which is constitutionally irritable. This is the inheritance of the unquiet spirit. It may terminate in phrenitis, mania, or fatuity. " It appeal's," says Dr Parry, " that a certain determination of blood to the brain is absolutely ne- cessary for the support and continuance of all its functions." If the circulation be too weak, there is a correspond- ing diminution of physical and moral power. Syncope and death may be its consequences. " If, on the other hand, there be an increase in the momentum of the blood, sensation is increased, thought is more rapid, and sleep is almost always wanting ; or, if, after some long interval, the patient for a moment forgets the surrounding objects, horrid images pre- sent themselves to his sense of seeing, so exactly mocking realities, that he starts out of his sleep vio- lently, and for a while hardly believes that he was in a dream." These are the extremes of a state of things of which there are all degrees, and of which headache is the premonitory affection. We must quote again from this author : — " This momentum producing excessive impulse on susceptible parts, seems to be one of the HEADACHE, 145 chief causes of Avhat may be called idiopathic pain in the animal frame." An attentive perusal of the elements of pathology v,i\\ convince the reader that Dr Parry does not at all embrace the views of the humoral pathologists. It is a question not of quality but of quantity, which is agitated ; but undue quantity may eventually, by its influence on the nervous system, deteriorate the quality. Deep thought occasions headache, as all who have thought at all, or, perhaps, I should say, all irritable and susceptible persons, must have experienced. This momentary sensation may be relieved by a temporary cessation from thought, for thought is under the power of the will as much as muscular motion. In the " Travelling Physician," I have cited a case of confusion of intellect from directing thought to any one subject, however insignificant or grave it may be. It produces a sort of reverie which passes away upon seeking quiet. There is much truth in the parody of Childe Harold, in the Rejected Addresses ; for in such circum- stances, " Thinking is but an idle waste of thought." This state is, I believe, owing to decrease of blood on the brain. It is consequent upon some cause Avhich impedes the circulation through the heart, for it is accompanied by a sense of fulness, which is relieved by frequent gaping. It may be what is termed purely nervous, and accounted for in this way : — The loss of the thread of reasoning, which would be but momentary u 146 HEADACHE. in many instances, excites alarm in a very susceptible constitution, and this as much as pain diminishes the action of the heart. The moral first acts upon the physical, which reacts upon the moral, and the very endeavour to get out of the labyrinth becomes a cause of failure. I have known this state occur after great anxiety of mind. It is momentary, and is dissipated by the horizontal posture and the free return of blood through the heart, as the gaping indicates. Nothing so much resembles the waking dream as this state while it lasts. There is a common form of headache, arising from deficient circulation in the brain when the vessels are emptied of their blood too rapidly, or when, from congestion in other organs, the balance is destroyed. The case of varicose veins, as before quoted, is highly instructive in acquainting us with the immediate effects of abstraction of blood from the brain, causing syncope. This headache is found mostly in females who have borne many children, or have been liable to large periodical discharges of blood. It is a constant affec- tion ; the head is seldom free from pain ; but the paroxysms are sometimes more severe than at others. In these cases the hair generally falls off early in life, the feet are generally cold, and the hands and fingers benumbed. The blood is in undue proportion in the viscera; and this state of things is generally accompanied by constipation. Now, although the indication here is to rouse the nervous system, yet I have not found that wine is of much service. The shower-bath is decidedly HEADACHE. 147 in many cases useful, and should be follo\A'ed by warm hand rubbing. The patient should also be cased in flannel; and the use of the flesh-brush, well applied by a good assistant, is highly beneficial in such cases. As far as medicine is concerned, it is diflScult to make choice of a tonic which has not some drawback, from the disposition to constipation being increased under its use. A combination of blue pill and colocynth twice a week will generally be necessary, in conjunction with bark and steel. The vegetable bitters do not seem to have any decided effect in these cases, and arsenic is never indicated in such. The hygean me- thod is more to be relied on than any specific plan of treatment. Exercise is of great importance in con- ducing to a regular distribution of the circulating fluid. It should never be excessive nor carried to fatigue, but it should be persevered in constantly, and in all weathers. I think that it Avas a saying of George the Third, that there was not a day in the year in which he could not take a walk ; and much as it has been a fashion to abuse our climate, there are few which allow of so much exercise in the open air as does that of England. Warm clothing in winter, thick-soled shoes in damp w^eather, and change of apparel, defy all weathers. It is the perseverance in finding health that is wanting, whereas many will per- severe too long in losing it, not deceiving themselACs either, but sinning with their eyes open ; for none endowed with common sense Avill plead ignorance of the i)ernicious effects of indulgence in the table, — late iiours, heated rooms, and the penalties of society. 148 HEADACHE. The headaches consequent upon want of proper circulation in the brain depend upon the loss of that tone in the nerves which is imparted to them by the blood. It is probable that the capillaries become debilitated, and that the circulation is not free in these vessels, from a deficiency of the vis a tergo. Mere congestion is not inflammation, although it may eventually lead to it. I have known these headaches entirely relieved by excitement. I have known ladies leave their couch when suffering from violent pain in the head, and lose it in the ball-room. The pleasure and exercise of the dance have relieved this state for the time. It has naturally returned with increased force. The headache, from increased determination of blood to the head, which commences by slow and insidious degrees, is of the most dangerous and irre- mediable kind. It terminates in the different ways before mentioned. This is not the species of headache characterized by being confined to any one point or region, by return- ing periodically and disappearing instantaneously ; but it occupies the whole head, and is seated in the membranes of the brain. It is always present, but subject to great fluctuations as to the amount of pain. Paroxysms may occur which border on insanity. Long endurance of pain, not sufficient to produce this excitement, leads to loss of memory and fatuity. Of this an example has occurred to my knowledge in a most worthy and estimable colleague, whom I often met in consultation at St Petersburg. He always complained of headache, became absent by degrees ; his memory gradually failed him ; and, of HEADACHE. 149 course, his practice, which was very extensive, began to decHne. He finally lost his intellect for a time. I am not aware whether he has recovered it. There is a rapidity of thought and increase of intellectual power, caused by increased momentum of blood to the brain ; and so distinct is the impression left by this state on the writings of poets and authors of this class, that we can recognize at a glance, in different passages of their works, w^hat has been written during excitement and during exhaustion. They betray, in the characters of their heroes, their own feelings. I should say that Byron's death-bed scene of the Caloyer in the Gaiour is a true picture of what he had himself suffered in life : — '• I only watched, and wished to weep : I could not, for my burning brow Throbb'd to the very brain as now. » * * * * 1 would not, if I might, be blest — I want no Paradise but rest ! " We recognize in this the tortures of those headaches to which this noble author was a martyr ; and the last line contains no profane idea, but simply an expression that rest would of itself be a sufficient Paradise Avith- out any positive enjoyment. If the physical condition of this great genius had been better understood, he would not have been treated so harshly ; but it has been his fiite, as it has been of others, to be known and appreciated more and more as we recede from the period in which he lived. There is a much milder spirit manifested towards his Manes than Avas shown to him in his life. Few can snv what Scott did upon 150 HEADACHE. his death-bed : — " It is a comfort to me to think that I have tried to unsettle no man's faith, to corrupt no man's principle ; and that I have written nothing which, on my death-bed, I should wish to have blotted." The same cause operated in different ways to extin- guish these two lights. Byron and Scott fell sacrifices to mental excitement, operating, just as we might suppose it would, in beings of so different tempera- ments. The spark, too quickly blown upon, kindled a fire in the one which quickly consumed itself. In the other the spark became exhausted by slow combus- tion, without kindling into flame. It is said that Lucretius wrote his poem, de Rerum Natura, in the lucid intervals of reason and sense, during a fit of delirium ; and no one who is conversant with that production, can doubt of the state of mind under which it was composed. The opening of the second and third books, — " it would be profane to call it inspiration," — but still, " it is not of this world." Men like these generate organic disease by pur- suing their occupations to excess, and the completion of the mental offspring is fatal to the physical organs in which it was nurtured. Post mortem examinations discover thickening of the membranes, ossific deposits, congestion of the vessels, serous eflfiisions, — in some instances, abscesses in the brain. In the treatment of the studious man's headache, or that which is derived from mental occupation, of whatever kind it may be, provided it be attended with excitement, there are few means of relief to be expected from medicine, as long as the cause is allowed HEADACHE. 151 to operate. The preventive is the only effectual sys- tem, and this is difficult to accomplish ; for the man who writes for his bread cannot, the one who does so for his gratification will not, sacrifice to what is at first but a trifling headache, the intoxicating plea- sure of his mental labours; but it is the jy^incipiiis obsta which should be borne in mind. The cause acts by slow degrees in the beginning ; the increased mo- mentum of the blood produces in the commencement but an increase of mental function, and this is plea- surable to the individual ; but in the course of time, and by continual distension, the vessels lose their tone, and congestions follow ; these may be in any de- gree of severity, and removable by fresh impulse ; but this state leads to disorganization of membrane and of brain, and the whole nervous system is implicated in the consequences. Study and application should never be continued when they produce decided headache ; and if the mind cannot be idle, its occupation may be varied by lighter work. By such precaution the foundation of many a disease may be prevented. There is always time enough for the accomplishment of wholesome labour, and that which exceeds this point is criminal ; it is voluntary and gradual suicide, unjustifiable under any circumstances. The midnight oil is too willingly consumed by the studious, because there is, as tlie Germans state, a kind of hallucination in the system, and, moreover, the mind feels more at liberty to work when it is secure from interruption. The charm of midnight composition consists in the certainty that the train of thought shall not be disturbed by 152 HEADACHE. external causes. Neither the postman's rap nor the milk-woman's ring is expected at this hour in the great streets of the metropolis. The conversion of night into day is most pernicious to health, and those who spend nights in dissipation or study bear the stamp of it in then- front. To add evil to evil, green tea is often the beverage of the midnight book-worm, of which the trembling morning hand and the morning headache are but too true vouchers. There is but a shadow of difference in the state of him who has passed his night in a tavern, and of him who has passed it in his study. When the excitement of the night is over, morning exhaustion is alike in both ; the nerves in both are still reeling from intoxication. Collingwood used to complain of his evening cramps and spasms, and of his morning headaches, states no doubt induced, in that most meritorious officer, by long continued mental anxiety. The nervous system at- tacked at its source, every fibre must respond ; and patients themselves are sufficiently aware of the causes and ciFects of such headaches. If on examination of symptoms Avhich manifest themselves, we judge there is deranged structure, still relief may be afforded by medical means. A gentle but long continued use of mercury, Avith a moderately nutritious diet, and the most courageous moral conduct of the patient in resisting all temptation to over excitement, will produce a cure. The mem- branes of the brain may be thus disgorged of their contents, and even their adventitious coating dissolved, as is the case wuth congestions in other parts, by the absorbent power , but this can only be expected in HEADACHE. 153 incipient stages of disorganization. Quiet, abstraction of all excitement, early hours, moderate exercise, well regulated diet, avoidance of too much artificial light and heat, and the courage to accomplish all this, may ■work wonders even in aggravated cases. In this form of headache, I should not think of recommending the shower-bath ; the shock and reaction are opposed to the quiet enjoined ; but sponging the head with vinegar and water may be beneficial. The obstinacy of some headaches in another class of patients, has been attributable to the irritation of some bony excrescence, and, under such an idea, patients have been trepanned. I remember a case in Guy's Hospital, where a woman, under the care of the late Dr Currie, was subjected to this operation. The circle of bone removed was perfectly smooth internally, and Sir A. Cooper strongly reprobated the operation. Dr Good quotes some cases in which it proved successfid. In attributing many affections, commonly styled nervous, to the direct influence of the blood upon the nerves themselves, the question of its quantity rather than its quality has hitherto been agitated ; but the latter is not to be lost sight of in its operations, when these are in force, as a first cause. The blood may be deteriorated in quality by the absorption of oifend- iner agents from the oflandular structures, from the cavities of reflected membranes, from the inner coats of the intestines, &c., and produce many injurious effects to the system. Some of these have already been noticed ; among others, the bile, and, as the Germans maintain, the 154 HEADACHE. milk, which, when absorbed into the blood, Is a cause of puei'peral fever, mania, and phlegmatia dolens. The blood may be vitiated by the absoi'ptlon of the bile, and require a long time for its purification ; hence many of these jaundiced affections drag on for indefinite periods. It is probable, also, that the cholera of this country is attributable to the absorption of morbid secretions or unwholesome matters into the blood. When the latter is affected. It is not long before it manifests symptoms of the offence, and this Irritating the nerve in the fibre, produces spasm and contraction ; nor can it be doubted that many of the spasmodic affections and cramps of the stomach may also be due to quality of the fluid, which acts upon the nervous system and sets up disease, but it can only do so by Its influence over the other systems ; its condition as to itself is passive to itself in most affections of this nature. The blood is the food of the system, and this will be maintained in a healthy state only when it Is nou- rished by provender, proper in quantity and sound in quality. It Is rather in respect of the former than the latter that the blood for the most part sins, not absolutely, but relatively ; when undue quantity and deteriorated quality are combined, the effects are pro- portionally severe on the living solids. In all that has been stated, we trust there wUl not be found anything so uncanonical, as a desire to " forbid the banns between flesh and blood." SPASMODIC DISEASES. 155 PART VII. Epilepsy — Hysteria — Palsy — Catalepsy — Hydropohobia — Trismus Traumaticus — Delirium Tremens — Hooping Cougli — Chorea. SPASMODIC DISEASES. Dr "Wilson maintains in his work upon Spasm, Palsy, and Lano-uor, that " It is from what offends the blood in the fibre that spasm is produced for the most part in the voluntary muscles. The blood entire is sensitive as the individual nerve of external impres- sion, instantaneously and simultaneously perceived through all its distributions." These views are chieily grounded upon the eflPects of pioisons upon the blood. Although Drs Addison and Morgan deny that poisons are thus inti'oduced into the system, still let it be admitted that the poisons thus circulate and pro- duce their effects through the medium of the blood upon the brain. If a muscle be laid bare, and the filament of nerve with which it is supplied be irri- tated by the sharp pomt of any instrument, the fibre is thrown into contraction, and spasm is produced. This is at all times demonstrable ; but if it be asked whether the injury done to a single nerve by lesion or by poison, shall be as manifest in the system in the same space of time, or as universally, as when this is 156 SPASMODIC DISEASES. effected through the circulation, as is supposed to be the case where strychnine is injected into the veins, it must be answered in the negative. It cannot be ex- pected otherwise ; for how can the part so soon affect the whole as the whole the part ? In the first instance, the offence is transmitted through the sensitive nerves, along one line of route, to the brain and spinal mar- row, which take cognizance of it, as the motor nerves bear evidence. In the second, where the blood be- comes the medium of communication, the whole of the system is affected at one and the same time through the muscular fibre to the nervous filament, and so to the brain and spinal marrow directly and indirectly. That it is the nerve which alone is of- fended, and that the blood is passive in the business, is proved by the following experiment : — If a muscle be isolated, and the trunk of the principal nerve which supplies it be divided, then this muscle is not thrown into contraction by the injection of strychnine into the blood, although the whole muscular system be, with this exception, convulsed. It must be considered, in this respect, that the offence is in the blood which circulates freely through the isolated flesh ; but the nerve is wanting to express its sorrows. It cannot be allowed, I think, with due deference to the rebel author before quoted, " that the blood is sensitive as the individual nerve of external impres- tion, instantaneously and simultaneously perceived through all its distributions." Its derangement is only made manifest in the flesh, not in itself by any re- cognizable evidence ; and we see the flesh takes no cognizance of it, where no nerve is present. The SPASMODIC DISEASES. 157 experiments of Muller, moreoyer, prove, that the nerves are paralyzed by direct application of poison to them. " Certain as it is that the general effects of poison- ing depend on the absorption of the poison into the blood, nevertheless the action of poisons on the nerves cannot be denied The most obvious case of local paralysis of nerves by a narcotic poison, is the dilatation of the pupil and loss of contractile power of the iris consequent on the application of a drop of solution of extraction helhdonha'. In this instance the poison reaches the iris and the ciliary nerves, which are distributed to it by imbibition. It is evidently a local effort, and not in the slightest de- gree the result of absorption into the blood, for the pupil of the other eye is unaffected .... I dis- sected out the ischiadic nerve in a frog for a consider- able extent, and let it hang in a solution of acetate of morphia ; after a little time, I found that the end of the nerve had wholly lost its excitability." — P. 679. Upon what is the assertion grounded, that the blood is offended in the fibre ? It seems most probable, that the latter is offended by coming in contact with the noxious fluid, of which the nerve takes cognizance : For what proof have we that the blood is offended ? AVe ask for evidence in the blood itself. If so, why not manifest some evidence of the misdemeanour ? "Why arc we to look for this in the fibre rather than in the blood itself? The blood should be throAvn into contraction and spasm, and this, too, at the point wliere it is most immediately injured, the point of con- tact with the poison ; but of this we have no evidence; 158 SPASMODIC DISEASES. nay, we have proofs to the contrary ; for its current would be thus impeded, and this would prevent the diffusion of the poison throughout the system. If drawn from the body in this condition, does it evince proofs of being under, poisonous influence ? Does it coagulate more or less rapidly than under ordinary circumstan- ces ? The blood is not sentient of the noxious effects, or they would be first manifested in it. No effect is apparent till it is poured into the fibre, — till the nerve supplying that is ofi'ended, then contraction and spasm are induced, as w^e sec when we bare a muscle and irritate a nerve by the prick of a pointed instrument. The blood can only be looked upon as a vehicle in the operation. Could we isolate a part, drain away every drop of blood from its vessels, and fill them Avith water impregnated with poison, the same effects would be manifested as where the blood is the vehicle, upon granting, merely for argument sake, that this is the case. Some few instances are upon record, where the in- jury to a nerve is followed by immediate effects upon the spinal marrow, causing tetanus. Dr Gregory used to relate the case of a waiter who divided the fleshy part of the thumb in lifting a heavy dish off' the table ; the piece between the finger and thumb breaking off", he was immediately seized with spasms of the muscles, and died in less than an hour. When I was doing duty in the Edinburgh Infir- mary, a man was brought in whose thigh had been gored by a bull ; there was not much injuiy to the flesh, but several branches of nerves were exposed and lacerated. He died of tetanus within forty-eight hours. SPASMODIC DISEASES. 159 I had an interesting case of cholera during its pre- valence in St Petersburg, which illustrates the influ- ence of the circulating fluid on the muscular fibre and nervous filaments. An old lady had long suffered from numbness in the whole of the left arm and hand, which, though not amounting to paralysis, rendered the limb almost useless. She had tried all kind of stimulants and rubefacients without benefit, and had desisted from any farther attempts, as she said at her advanced age it was not of much consequence. She was attacked Avith spasmodic cholera in its most pain- ful form, and all the muscles of her body were tortured by spasms. She weathered the storm, however, and, to her great surprise, entirely recovered the use of her arm. There was a very general feeling of dislike in that city, and among a certain class, to allow that their friends died of cholera, — a certain odiiun was attached to the word as to the plague. If a patient resisted a few days, and died of its sequela, the com- mon parlance ran, — II n'est pas mort de cholera mais Ic cholera, a develope une maladie, que I'a tue. This was perhaps the only individual who could boast of proving this disease to be a remedial agent for other evils. In this case, the blood itself was in a poisonous state, and became the offending agent. It is immaterial in Avhat way the nerves were affected. The impression was made upon them generally. It is true that tlie influence of some poisons upon a nerve, is as great, and as instantaneous, and as general through the whole system, as if the entire mass of nerves had sinuiltaneously been sulyected to the impression through the medium of the circulation ; 160 SPASMODIC DISEASES. but this is not always the case. Midler asserts that the action of poison on a nerve is limited to the point of contact, and does not extend to the branches of the nerve. This, he says, accounts for the slow propaga- tion of the injury to the sound pai'ts, and the time which elapses before constitutional symptoms are manifested, which, when the blood is the medium of communication, are instantaneous, affecting the whole nervous system at once. It cannot be doubted that the blood may become poisoned by impression made upon the nervous system, without resorting to the supposition that the poison is first introduced into the system by the blood ; for nothing can be more instantaneous than the general effects of the single point of contact of some poisons, which imply as ready transit to the brain as can be effected through the circulating system. It would perhaps tend to clear up the matter, if we were to dilute the dose of poison with the quantity of fluid with which it must be mixed previous to getting to the brain, and inject this into the carotid of a living animal. This might decide whether the ImjH'ession were made upon the latter, by primary offence to the nerve in its concentrated state, or by means of circu- lation in its diluted form. There is, I think, room for more experiments upon this matter than have hitherto been attempted. There is no reason Avhy both these means should not be available in the system. Three powers are concerned In the formation of spasm — the nerves, the muscle, and the blood. Two of these are absolutely necessary to its existence, SPASMODIC DISEASES. 161 muscle and nerve. It is the irritation of the latter which thus manifests itself in the former. Muscular contraction cannot exist without the assistance of nerve. It is essential to it, and any experiments made upon muscle cut off from the brain, which may seem to prove the contrary, only proves that nervous fluid is still inherent in the nerves, supplying sufficient power to the muscles to make them contract. The blood contributes much to this effect, but it is not essential to it. Muscles drained of their blood, and washed out by warm water injected into their vessels, still contract when their nerves are stimulated. Blood may act in two ways in producing spasm, either by morbid influence on the muscle, through the nerve, or by mechanical excitement, through increased momen- tum. A case in the Philosophical Transactions for 1811, p. 89, is related of a " constant twitching of the fore-arm, which was suspended by compression of the carotid artery on the opposite side, while it was not diminished by pressure of the carotid on the same side." Although many poisonous substances seem almost inert Avhen introduced into the system by the stomach, others affect it almost as rapidly in this way as when applied to the nerves of a part exposed, or injected into the blood. I have known an over-dose of strych- nine produce immediate and fearful consequences. A patient had been taking small doses of this poison in a solution by tea-spoonfuls. I forget in what men- struum it was dissolved, but the nurse in attendance finding that the patient was purged, concluded he was taking a cathartic ; and, as she required a strong dose 162 EPILEPSY. — HYSTERIA. herself, took what there was in the phiaL She was soon convinced of her mistake. I was sent for to treat a person supposed to have swallowed poison, for her cries alarmed the neighbourhood. She rolled upon the ground, and every fibre in her frame was convulsed as if by electric shocks. She was vomited and purged most fm-iously. She ultimately recovered, but she was in a state of tremor for months afterwards. As far as I can judge, she might have swallowed about two grains of the extract. EPILEPSY.— HYSTERIA. These two diseases have been sometimes con- founded with each other; and when the latter has occurred in the male, it has been considered as epi- lepsy, although deficient in many of the characteristic symptoms. By whatever name it may be called, precisely the same train of symptoms sometimes show themselves in both sexes. If we adopt the French term, attaque des nerfs, there will be no room for cavil. A young collegian returned to see his friends in Russia, and was placed under my care. He was about nineteen years of age, of studious habits, high moral feeling, and most amiable disposition. He had been attacked at college with extraordinary symptoms, and was reported to have had one or two fits. I observed nothing particular about him at first, except a degree of wildness about the eye. He was in good bodily health, but had been recom- EPILEPSY. — HYSTERIA. 163 mended to pass a long vacation in the country, as it was considered that lie had been over studious, and was subject to partial loss of memory. Some time after his arrival, as he was sitting at table, he was observed to be rather absent, not to reply when spoken to, and to have his eyes fixed. As his friends were upon the qui vive, no notice was taken, and he slid off' his chair under the table. His eyes Avere turned up, his fists clenched, with much convul- sive movement of the mouth, but no foaming nor bitinn; the tono-ue. He was stiff" and motionless. In this state he was removed to a sofa, Avhere he slept for some hours, and when he awoke remembered no- thing that had passed. Nothing was said to him, for I was acquainted with what had transpired upon my arrival, and took no farther notice of it. I recom- mended air, exercise, and the use of the shoAver-bath. Some days afterwards a similar paroxysm mani- fested itself, but accompanied by more ludicrous an- tics, lie crawled round the room on his hands and feet, tried to climb up the walls of the room, and performed all kinds of tricks, — rolling himself into a ball, &c. He kncAv nothing of what he had per- formed when he returned to himself. He was now seen by two English physicians, in company with myself. AVe agreed completely as to the nature of the case, — did not look upon it in a serious light, — recommended sea-bathing, amusements of all kinds, and travelling. We did not think it Avorth Avhile to prescribe any medicine, and we all referred it to that condition which Sydenham speaks of in his chapter on Rheumatism, — o«r yofv KXcopof. He started 164 EPILEPSY. — HYSTERIA. for Planover, where he was addressed to some emi- nent physician, who took a totally different view of his case, — said it was a confirmed case of epilepsy, and gave him large quantities of indigo, which natu- rally did no good. He returned again to college, where he was subject to the same attacks occasionally; but the following year he relaxed in his studies, formed an early matrimonial connexion, and has never since had the slightest return of his complaint. We were thus confirmed in the belief that both our diagnosis and prognosis were right, and had no hesi- tation in giving the disease the name of Hysteria. I should have mentioned, that copious secretion of limpid urine accompanied all these attacks. I have never met with a similar case, though I have fre- quently seen hysteric paroxysms in youths, but never in the same degree. Dr Wilson has mentioned a feature in the history of small-pox, viz. that the disease is often ushered in by an epileptic fit. The same observation has been made by Cullen iu his Outlines, and w^as much dwelt upon by Dr Gregory in his Lectures. It can hardly be a proof of the poison in the blood acting upon the nerves. It is a curious fact, but the Avhole of this disease is involved in so much obscurity, that it is diflfi- cult to draw any certain conclusions from it. Worms in the intestines will equally give rise to it. A lady, the wnfe of my late colleague, Dr , was attacked in three successive pregnancies, about the period of quickening, with a single fit of epilepsy ; at no other period had she ever showed the least disposition to a renewal of these attacks. EPILEPSY. — HYSTERIA. 165 Laennec, who inclines to favour the humoral patho- logy, considers the state of the fluids to be the cause of convulsions and epilepsy from spontaneous conges- tions. The blood, in such as have died of these affections, resembles that found in those killed by electricity. It may be as reasonable to suppose, that the shock given to the nervous system has been suffi- cient to kill the blood, decompose it, and, by arrest- ing the circulation, give rise to these congestions. This is precisely what takes place in death by lightning; the nervous system is annihilated, as it also is by a severe blow on the stomach, causing instant death, and the same appearance in the blood. It is deprived, by the absence of coagulation, of the testamentary evidence that it has ever lived. Epilepsy is a very common disease in Russia. I liave seen a great many cases, but never known any relieved permanently. I had a lady under my care for some years, who was seized for the first time in her eleventh pregnancy. The child was born at the natural time, and lived. The mother Avas ever after subject to slight attacks. She bore no more children. She was about forty-five when this first occurred. There was nothing worth recording in the case, except the very singular way in which she experienced wamhigs of the approach of an attack. She was a most amiable woman, and felt distressed at the state of her mind at these times. She never knew that she had epileptic fits; this was always kept from her know- ledge. She supposed herself subject to fainting fits. She one day complained to me that she did not know 166 EPILEPSY. — HYSTERIA. how it was, she could not explain it, but nothing seemed right ; the month, the week, the day, the season, the house in which she lived, her children, nothing seemed as it ought to be. These were her very words, and she burst into tears. Some similar moral condition preceded every attack. In the pa- roxysm she bit her tongue and foamed at the mouth, so as to leave no doubt as to the nature of the disease. I have seen epilepsy, in very aggravated forms, lead to imbecility of mind. A young lady of twenty years of age, after suffering from childhood, and that to such a degree as never to be considered safe when alone, being subject to paroxysms which lasted two and three days and nights, requiring the manual aid of several attendants to control the force of such muscular power, as was hardly credible, was cured permanently by removal from the country. She has had no return of her complaint for years, and is so improved in looks and in mind as to seem a different being. There was nothing left untried, and many were consulted upon her case without any benefit to herself. Emigration cured her. Dr Baillie said, in his day, that palsy was upon the increase. I have been much surprised, since my return to England, at the number of people whom I meet in the streets dragging a leg along. I can- not speak comparatively upon this subject, as I do not recollect what ])roportion this state bears here to what it did in former times. It is but too evident that the nerves, when once injured, are not so easily restored to their healthy condition, and their import- ance is made manifest in their derangement. How EPILEPSY. — HYSTERIA. 167 few of such cases ever completely recover. It Is not improbable that the universal system of blood letting upon all such attacks, and even threatenings of them, has converted remediable into incurable diseases. Paralysis has sometimes immediately followed the depletion intended to prevent apoplexy ; and where this plan has been persevered in for the relief of flow of blood to the head, it is not an uncommon conse- quence. Dr Holland has commented very freely upon this in his Notes and Reflections : — " I have known cases of this kind where bleeding has immediately been followed by convulsions of epileptic character, occasionally by amaurosis, or deafness, more frequently still by rambling delirium, and where wine or other cordials have as speedily abated these tendencies." Sir Charles Bell has stated, I think, in some of his earlier surgical productions, that when a man is taken up in the streets apparently lifeless from the con- cussion of a fall, the nurse gives him a dram, and the surgeon bleeds him; but the nurse is right. As Dr Holland observes, " The use of the lancet is easy, and gives a show of activity in the practitioner at moments wlien there appears peculiar need of this promptitude. Current opinions and prejudices are wholly on the side of bleeding, and the complexity and danger of cases tend to obscure the results of the treatment. The physician needs all his firmness to decline a practice thus called for, Avhere the event is so doubtful, and where death may be charged upon his presumed feebleness or neglect." The whole body medical might be appealed to if tiioy have not, particularly in their early career, had 168 EPILEPSY. — HYSTERIA. to contend with such popular feeling. They have felt their reputation at stake, they have been thoroughly convinced that every blame would be attributable to them if they did not immediately bleed their patient ; by doing so they would place themselves on the safe side ; and, as Dr IMacculloch has justly observed, whatever might be the consequence where copious depletion has been used, the friends will always express themselves, " that every thing was done that could have been done." This we see again and again with the same results ; we hear daily of paralytic seizures where medical aid was immediately at hand, so that the patients were bled, but still to no good purpose. I w^as strolling along the quay in St Petersburg, and seeing a crowd at the door of the principal banker, I walked into the house. I was immediately requested to bleed a orentleman who had fallen from his desk in a fit. I knew the patient ; and, from his appearance, and previous knowledge of his habits, it appeared to me that his nervous power had failed him. I hesi- tated, therefore, in spite of the pressing demands of the friends, to bleed a man in apoplexy. In this dilemma I was fortunately relieved by the timely visit of the gentleman's medical attendant. He was authority in the case, and a cordial was administered, w'hich soon revived the patient, who had been long in a nervous state of health. Upon another occasion, I was sent for, very early in the morning, to see a patient who had been sud- denly seized in the night with inflammation of the lungs. He was in great pain, as I was informed, EPILEPSY. — HYSTEPJA. 1G9 and could not breathe. Upon my arrival, I found a basin and tea-cups, with bandages, lying upon a table, by his bed-side. All was in readiness ; but it was a case of gout in the stomach, and was immediately relieved by a full dose of brandy and laudanum. I think I have seen good effects from strichnine in cases of paralysis, when steadily continued. I re- member a case treated by the late Dr Birkbeck, at the General Dispensary in Aldersgate Street, by the powder of nux vomica. The woman, whose leg was palsied, made a better walk of it every time she attended. I cannot say that a perfect cure was effected, for I lost sight of her ; but the doctor was so much satisfied with the progress which she made under this treatment, that he made mention of it at a meeting of the INIcdico-Chirurgical Society. The value of this medicine is fully recognized in palsy from lead, and mentioned by Dr Marx of Gottingen; Tetanus and Paralysis afford us the strongest patho- logical proofs of the importance of the nerves, and of the extreme difficulty of restoring them to their normal state, when affected by disease. As I am now Avriting, I am informed by letter of a former patient who, by a paralytic stroke, has irretrievably lost the use of her left side. This is a forcible term, but one too easily understood. We do not call the case irretrievable when the blood is in a morbid state. In the very same family, I have known a parturient female so exhausted by hcmorrhagy in many of her confinements, that there have been moments when life has been almost judged extinct, yet this was not an irretrievable state. I 170 EPILEPSY. — HYSTERIA. In the treatment of Palsy and Tetanus, the field is still open, as we may hope, for great and useful discoveries. When I was at Wildbad, in Germany, I heard of many cases which had been much benefited by immersion in the hot springs which gush from the rocks. The supposed advantage of these baths over others, is the equable temperature which is maintained during the whole period of immersion. The hot water continues to flow over the surface of the same degree of heat, and always renewing itself from the same source. The body leaves the bath with the same impression which it received upon entering it. The water is, in this case, continually renewed ; w^hereas in others, the temperature lowering, fresh heat must be applied ; and this can never be so arrano-ed as that some difference of sensation be not experienced. This is the sole advantage which the baths at Wildbad boast ; for no active ingredients are found in the waters. The question has been agitated, and upon rational grounds, Avhether these natural re- servoirs of caloric do not possess some chemical elec- tric principles, not to be developed in the artificially heated cauldron, which did not bubble — bubble till the witches had thrown their charms into it. W^e must not refuse evidence till we have more knowledge than we at present possess of nature's chemical combinations. The arteries which supply a paralyzed Hmb beat with less force than previously, and animal tempera- ture falls as a natural consequence, both evidences of diminution of nervous power.* * The French term is very expressive, un bras rpfroidi — a paralyzed arm. EPILEPSY. — HYSTERIA. 171. In cases of what the French style apoplexie fou- droyante, and where blood is effused into the cere- bellum, there is a symptom sufficiently indicative of the precise scat of the lesion. The grasping motion of the hand which I once witnessed in a patient who lived about twelve hours after the blow, was the only sio-n of voluntary action which remained till his death. It was incessant, and distressing to the bystanders in every sense. The nerves alone must bear the shame of such excitement. The following case may deserve the title of slight catalepsy ; it is the only one I have ever seen : — A lady, fifty years of age, and of most nervous temperament, who had been an invalid for years, subject to constant headaches, never free from cough with copious expectoration, her hands and fingers always in a state of tremor, her temper very irritable, and the alvinc secretions continually out of order, was suddenly seized with a fit ; such was the account the messenger brought me. I was in the immediate neighbourhood, and saw her in less than ten minutes after the attack. She had fallen off the bed upon which she had been re- posing, about six o'clock in the afternoon. She was replaced upon the couch ; her face was much as usual, perhaps a little paler, the eyes were semi-closed and immoveable, the pulse was quite natural, or a little slower than usual ; one arm was raised towards the head, bent, and the fingers clenched ; the other was stiflf' and straight by her side ; the animal heat was natural. She was perfectly insensible to the im- pression of noise, nor did she feel, apparently, any 172 EPILEPSY. — IIYSTEPJA. effort made to straigliten the arm. She remained in this state for nearly an hour, during which nothing more was done than bathino; her head and face with cold vinegar and water, and occasionally a few drops of a?ther, were poured upon the scalp. She returned to the normal state by degrees, first opening the eyes, and relaxing the arm. She could not speak for a long time, but became thoroughly conscious. At length she said " I am coming round ; " the pulse became quicker and smaller, and a moisture appeared on the surface. She was allowed to remain quiet, and got some refreshing sleep. I remained the night with her. When she awoke she was not in the least conscious of any thing that had passed. She was feeble and much depressed. Strong cathartic enemas opened the bowels. Cam- I)hor and ammonia were given internally at short in- tei'vals. For some days afterwards she was much inclined to sleep, but the drowsiness did not amount to coma. Her usual copious expectoration was much diminished. She then began to have a good and bad day alternately ; and upon the bad day there was evi- dently a chill in the morning for some time. She got warmer and better as the day wore on. My colleague, Dr Handyside, who saw her repeatedly, was con- vinced with myself that there was a decided inter- mittent tendency. She had never been able to take bark, as it caused constipation, and we gave her Fowler's solution, but the prejudice was too strong against it, and we determined upon employing quinine, combined with purgatives. She recovered rapidly under its use. EPILEPSY. — HYSTERIA. 173 For several years afterwards she had no return of this affection, whatever name it deserves. She was always, however, subject to nervous derangement. I must here observe, that Ave incurred the highest censure for not bleeding her* The practice was stig- matised as puerile and inert, and if she had succumbed ■we should have been held responsible for our want of energy. I am convinced that if we had bled her, and even paralysis had followed, nothing but appro- bation would have greeted us for having done all in our power. Some physicians, perhaps, have met with the fol- lowing case : — A gentleman, past the middle age, who has been in the habit of living freely, has taken some whim into his head, either that he Avas getting too fat, or that he should enjoy better health (having in reality no fault to find with his actual state) if he entirely changed his mode of life. He leaves off wine and malt liquor, takes strong exercise to fatigue, and lives upon tea and toast, w'ith little animal food. After some time of such probation, he is attacked with para- lysis. I knew a country squire, a fox-hunter, avIio pursued this plan, and with this result ; and I believe that very lately a celebrated vocalist, under the im- pression, that by changing his mode of life he might prolong it indefinitely, has fallen a victim to his ex- periment. I shall be surprised if many Avho take Father Alathew's pledge do not fall into the same snare. The nervous system will not tolerate these sudden changes with iniuunitv. An excess of abstemiousness 174 HYDROPHOBIA. is dangerous to the man who has, perhaps, sinned in the other way, and particularly at a certain period of life. If he be Misely determined to reform his habits, let him do it gradually, and he will do so safely, — Chi va piano va sano, va sano va lontano. HYDROPHOBIA. The following circumstances, which occurred in St Petersburg before I inhabited that city, were detailed to me by persons who were eye witnesses of the facts. The case occurred on the premises of an English merchant, and the victim was a young Englishman, one of the counting-house clerks. He had been in the constant and foolish habit of teazing a large dog, chained to his kennel in the yard. The animal was so enraged with him from being pelted with stones, and flicked with a long whip at a distance, that he made constant efforts to seize him, which, one day, by sudden snapping of his chain, or disengaging his head from his collar, he was able to accomplish. He bit him in the hand. No particular notice was taken of this at the time, but a few days afterwards the young man was attacked by symptoms of the disease, of which he died, with all its accompanying horrors. This case offers matter for consideration, and pre- sents a double proof of the nervous influence in forming the malady, and in its reproduction by ino- culation. That hydrophobia can be thus generated spontaneously by the influence of passion upon chang- ing a natural secretion, or concocting one sui generis, HYDROPHOBIA. 175 there can be no longer any doubt. The animal had not shewn any symptoms of disease previously. He was made mad literally, not figuratively, by irritation and torment. Whence the secretion might have been derived which produced such dire effects on the human subject by inoculation, its morbid state was engendered by the influence of nervous ex- citement. It is as evident that the poison was generated under this state of phrenzy, as that the milk of a woman's breast is changed in quality by a fit of passion. As regards the disease, when developed in the human subject, its whole history and course refer it to the nem-oses. I have never had but one opportunity of seeing a hydrophobic patient. It was in Guy"s Hospital, and prussic acid was largely administered, but with as little effect as all its predecessors. The patient was a master carpenter, an intelligent man, who seemed to wish to give information as to his wretched state. It was not a dread of water, but of lluids, which agitated him ; and as he lay in a corner of the Avard, he Avas so convulsed by the trickling of tlie rain down a spout on the outside, that he was re- moved to the centre of the ward, Avhere he could not hear it. His nervous instability was appalling. I can never forget his countenance. His friends insisted upon removing him, and it \vas impossible to prevent them. Two men carried him out on their shoulders ; as they descended the steps leading down to the outer quadrangle, he made a sudden spring and fell dead upon the pavement. Whether it was the last strug- gle of life, or whether the concussion from falling with 176 TRISMUS TRAUMATICUS. such effort on the pavement, caused immediate death, may be doubtful.* There is a similar case related by Dr Good, vol. iii. p. 275, of spontaneous lyssa, reported by Mr Zitman. Is the generation of the poison which is fatal to the human subject by inoculation positively so to the ani- mal itself? If there is a suspicion of the dog, he is immediately killed; but have not people gone mad who have only been reminded of having been bitten by the appearance of the disease long afterwards ; and in such cases are there always proofs of the dog's having died after biting the person ? TRISMUS TRAUMATICUS. I have seen this produced by the application of a blister in scarlatina. The patient w^as a child of eight years of age, to whose chest a blister was applied to relieve dyspna?a. The wound sphacelated, and gave rise to trismus, which lasted two or three days, and the child sank. In the same family, a blis- ter applied to the neck of a young woman of twenty, attacked by the same disease, ran into gangrene in twenty hours. She died in fifty hours from the first symptoms of the eruption. * Since writing tliis, a letter from St Petersburg informs me of the death of a respectable Englishman, who died from fright. He was snapped at by a dog running through the streets, and the dog seized the tailof his coat, but did not bite him. He was so prepossessed with the idea that he should die of hydrophobia, that he fell a victim to his fear. ■^2dd Jiiit/ inu. DELIRIUM TREMENS. 177 DELIRTUM TREMENS. This is a very common disease in St Petersburg. It is found only among the lower orders, and hence being an hospital disease, practitioners in private have not much opportunity of seeing it. The higher class of Russians are very moderate livers, and indulge but little in wines or spirituous liquors. I have met with this disease several times amongst the counting house clerks, who carry out the bills, &c., termed artelcheks. Cold has certainly much to do with it, for it encourages drinking of spirits ; and when once this class of people take these to intoxication, they continue to do so for days and weeks afterwards. I have, in another pul^lication, described what is techni- cally styled a Zappoi. There is nothing peculiar in the delirium tremens, so produced, to require further com- ment. It always proved fatal in the cases which 1 treated. In the naval hospitals, Avhere it is very prevalent, opium and musk sometimes succeed in saving the patient. In a numerous class of spasmodic disorders we require nothing more than moral excitement to de- monstrate their nervous origin. It matters not by what means indeed they may be produced, and by none more generally than by changes in the balance of the circulation ; it is the nerve which speaks, the nerve which suffers. This system may, from its great intricacy, its reflex action, sometimes lead us astray : we may get upon a wrong scent, but when we have threaded its mazes and labyrinths, we come to earth 178 DELIRIUM TREMENS. there. Muscle can no more be thrown into contrac- tion without nerve, than a hare can run with its legs broken. Singultus is a troublesome spasmodic affection of the diaplu-agm and respiratory muscles. It may be caused by increased determination of blood irritating t'ae nerves of the stomach, but we know that any thing which excites the moral feelings immediately suspends it. We check it in children by fear. Hoop- ing cough is a disease of a spasmodic character, and I believe the brain to be more or less affected in this disorder. Its nervous nature is proved by the habit Avhich the system acquires under its influence, and which continues long after the essence of the disease has been destroyed. I may here mention the treatment which we find most useful in northern climates. We have not the advantage of changing the air for a long period, so that the complaint is often of formidable duration ; but as soon as the febrile stage has subsided, which generally takes place tow^ards the end of the third week, doses of musk seem to have a specific influence. I have seen the most happy effects from its use, both in the general practice of my colleagues, and ray own, in St Petersburg. A grain of musk three or four times a-day, will, in general, arrest the most convulsive species of coughing in a few days. I have generally, in the early stages, experienced great advantage from the application of leeches to the temples ; for I believe that there is very often congestion in the brain, and that the latter, if not previously, is often secondarily, affected. DELIRIUM TREMENS. 179 It has been stated, but it may perhaps Avant more confii-mation, that it is suspended by vaccination ; but does it not return again after the local irritation has subsided? In this respect its nervous character is only more strongly indicated, for these affections are especially relieved by setting up new action in the system, or by metastasis from one mucous membrane to another, of which, in convulsive cough, simulating pertussis, I have known instances. The force of habit is very considerable in influenc- ing such affections, and reproduces symptoms of the original disease when its specific character has been destroyed. Thus, pertussis may be apparently cured for months, when, upon the accession of a catarrh, the convulsive cough returns, for which the same treat- ment would no longer be available. This is not con- fined to this species of irritation alone, for some are subject to habitual cough, observing certain periods, and subject to renewal from the slightest causes. These spasmodic affections require very different treat- ment ; they are nervous affections, to be relieved only by removing the exciting causes to the nerves, which may be plethora on the one hand, or debility on the other. Hence we treat some by digitals, — antimony, — others by stimulants, of which ammonia is the most powerful. In some cases, the moment of changing a line of practice becomes very critical. In the ad- vanced stages of pneumonia the cough and expectora- tion suddenly cease, and the pain, which had been subdued, as suddenly returns. Here depletion would be instantaneously fatal ; and it is only by rousing the nervous system, to excite the bronchia? to expel accu- 180 CHOREA. mulated secretion, or to stimulate the vessels to renew this, if it be suspended by a fresh access of inflamma- tion, that life is preserved. In the advanced stages of ptysis we often find the cough subdued and the expectoration diminished, affording hopes to the patient, who, by this very cir- cumstance, is placed in extremis. CHOREA. Dr Depp, chief physician to the Foundling Hospi- tal in St Petersburg, acquired a great and deserved reputation for his success in the treatment of this disease. His plan was almost wholly confined to the use of the shower-bath at all seasons of the year ; and as soon as the weather permitted, he removed his patients into the country, selecting as elevated a position as pos- sible, that they might enjoy the advantages of a brac- ing atmosphere. He insisted also upon the hair being cut close, and the head spunged with cold vinegar and water at several periods during the day ; the shower- bath to be employed as soon as the patient left the bed, or rather hard mattress, which he also insisted upon. He prescribed few medicines, and nothing usurping the name of a specific. The bowels were to be regulated by the mildest purgatives, but the shower- bath seemed to supersede the necessity of these. I saw but few cases of this singular affection, but a very aggravated one was most materially relieved by this treatment. CHOLERA MORBUS. 181 PART VIII. Cholera Morbus — Scorbutus — Diabetes. CHOLERA MORBUS. I HAD, during my residence in St Petersburg, some opportunities of seeing this disease in its most mur- derous form ; for the deaths in the city averaged more than a thousand daily at its onset. I published the results of some of my experience, and now, after a lapse of fourteen years, I must subscribe to the truth of Dr Holland's assertion, as expressed, page 568, in his Notes and Observations : — " That strange pesti- lence of our time, which, while affrighting every part of the world by its ravages, has seemed to put at nought all speculations as to its causes, or the laws which govern its course; — a disease, nevertheless, which, by the mystery of its first appearance, its suddenness, inequality and fatality, and the failure hitherto of every method of treatment, may well excite the inquiry of all who are zealous for the extension of medical science." The idea of its originating in insect life was adopted by several German professors very soon after its first appearance. The eccentric movements of the malady, its zigzag direction quitting the broad line of route, flying off at a tangent to appear in a widely distant point, would all argue certain atmospheric cm-rents wafting their 182 CHOLEEA MORBUS. poisonous contents in regions, beyond our powers of arrest.* Dr Prout's observations, proving that there was a constant increase in the weight of the atmo- sphere, deserve much attention in our future investi- gations, for this may not have been a casual coinci- dence; its constancy during the whole prevalency of the disease militates against this opinion. Freely con- fessing that what we pi'ofessed to know about this plague, when in the heat of the battle, was but mere presumption, we still pertinaceously adhere to the belief of its non-contagious character ; and we repeat, in the words of our former little treatise, " As far as my practice is concerned, both in the quarter allotted me, and also in private houses in different parts of the town, I have no proof whatever that the disease is contagious. In one case I attended a carpenter in a large room, where there were at least thirty other workmen, who all slept upon the floor among the shavings, and though this was a very severe and fatal case, no other instance occurred among his companions. In private practice, and amongst those in easy circumstances, I have known the wife attend the husband, the husband the wife, parents their children, children their parents, and in fatal cases too, where, from long attendance and anxiety of mind, we might conceive the influence of predisposition to operate, yet in no instance have I found the disease communicated to the attendants ; ... so that, as far as proof can be drawn from my own limited experience, I have none to offer in favour of contagion." In the ^ This would equally apply to Malaria, which i.s transportable in this way, as proved by Dr Macculloch. CHOLERA MOEBUS. 183 history of its prevalence in St Petersburg, it is certain that the anti-contagionists did increase with the increase of the disease ; and its spread over Europe has considerably increased their ranks, and the number of those has much diminished who contributed at one time to excite so much alarm among the people. This is, perhaps, all the knowledge we have gained upon the subject, and the evidence has been sufficient to convince most that the disease has nothing in its form or features, nor in its mode of propagation, which can entitle it to rank amongst those of a positively contagious character. Even negative evidence may become positive in certain circumstances, and of this the town of Odessa has furnished convincing proofs at two separate periods since the retreat of the cholera from Europe. It was found that the strictest military cordons did not, in any country whatever, arrest its progress. It stole its way through them, dodged the sentries, — defied the point of the sword and bayonet. It is said to have reached Sunderland by a ship which left Hamburg before it was recognized to exist in that city, where its appearance, some days afterwards, was sufficient, with some logicians, to prove that it was imported from thence. It must be recollected that none of the crew were attacked by it on the voyage; and here we may quote Dr Holland: — " Nor will previous communication, though certainly concerned in part in the transmission of the disorder, resolve these sin- gularities." It was not human contagion that operated in this instance. Still this distinguished physician observes, '' ]\Ian becomes an agent in the diffusion," p. 577 ; and, again, in his hypothesis of insect life as 184 CHOLERA MORBUS. a cause of tliis disease, he observes, " But also pos- sessing the power of reproducing itself, so as to spread the disorder by fresh creation of the virus which ori- ginally produced it." — P. 574. To return to the Hamburg brig which discharged her cholera cargo at Sunderland, and might then, as far as her crew was concerned, have got a clean bill of health, it is still an anomaly, that she should trans- port a disease from a town w here it did not exist when she left the port, when so many more ships could not effect this Avhich left infected ports. This was the case with Elsinore, where upwards of five hundred vessels touched, all chartered in the port of Cronstadt, where the cholera raged furiously. We do not know that up to the present day this town was visited by a single case, although its vis a vis across the Sound, the Swedish town, where no vessels touched, suffered severely. This is one of the inexplicable frolics of this disease. Now, with respect to the negative evidence, which becomes positive. The plague has twice been imported into Odessa from Turkey within the last few years, and several have died of it ; but by means of rigid quarantines and cordons, and the energy which Count Woronzoff displayed in arresting its progress, such as hano-ing a Jew who was about to violate the laws established, not a single death occurred without the city ; the plague never got out of the gates. Why should not the same observances and precau- tions, for they were the same, have succeeded in both cases. The cholera has never been arrested by human means in its progress — the plague often. CHOLEKA MORBUS. 185 AVhen the former has located itself in a country, it will be easy enough for those so disposed to find evidence of its human communication and propagation from one town to another. A man may take it by railroad from Liverpool to Manchester, at least be supposed to do so ; but have we evidence of its first invasion in this way wherever it has appeared ? Has any landsman, any sailor, made his appearance in any place with the disease upon him, and first communicated it to the inhabitants of town or village ? It was not so pro- pagated in Sunderland. It was not so in St Peters- burg. Hundreds came into the latter city from ]\Ioscow, where it raged eight months previously, not a soul was affected on the whole line of route. When it did appear, the same anomaly was presented as in the Hamburg ship. It was said to be brought down by the tallow barks from the frontiers of Siberia, though not a single baro;eman had been affected dur- ing the long transit. The man Avho Avas said to be first affected was not so till after his arrival in St Petersburg. In three days every quarter of that wide spreading city was grievously punished by the disease. The man died in the suburbs of the town amongst the lowest class of the inhabitants, none of whom coiild directly, or indirectly, have communicated with the higher orders. Many locked themselves up in their rooms as soon as the disease was announced, and died isolated from hvmian communication. There was no more proof that the bargeman brought it than that he fijund it at St Petersburg. It is the argument ad ahaurdam to say that it should take a tortuous route of three thousand miles to arrive there, when it was 186 CHOLERA MORBUS. raging for seven months at Moscow, a distance of five hundred only, and with which there were all the time daily communications, A fact well worthy of note is the circumstance, that of the eleven medical men who fell a sacrifice to it in St Petersburg, they were almost all practitioners who had the least to do with it — men practising in private, and not those who were attached to the great hospi- tals, of v\^hom I do not recollect that more than one perished ; and precisely the same observation Avas made by one of our colleagues who practised in Dantzic. As regards the nature of the disease, Dr Wilson has observed : — " Epidemic cholera is the result of an atmospheric poison, or other vice in the blood." I had two opportunities of seeing its attack — of recognizing the first symptoms of its presence. I observed a. labourer who was walking in the street stagger, reel, put his hand to his head, and fall down. I thought he was in liquor, and overcome by the heat of a bm-ning sun. Upon approaching him, I found him attacked b}^ cholera. He was removed to the nearest hospital. I do not know his fate. A director of one of the cholera hospitals was presiding at a committee where I was present. In discussing some matter Avith one of the physicians, he suddenly put his hand to his forehead, and complained of a shooting pain through his head, Avhich he attributed to having taken a pinch of strong snuff. It increased, however, in the evening. It was the commencement of the disease, which carried him oflP on the fifth day. In these two cases it would appear CHOLERA MORBUS. 187 that the brain was first attacked. In some few in- stances it hardly deserved the name of spasmodic, to judo-e from the outward manifestation of spasm. I have known it kill in six hours without much pain in the muscular fibre, but here the injury done to the nerves was more manifest. The derangement of all those fimctions under their control, — as the loss of animal heat, suspension of secretions, conversion of insensible perspiration into clammy sweat, the almost involuntary pouring out of the contents of the stomach, all proved how much the great vital power was para- lysed. Of the offence to the blood, there can be no doubt, and of the reaction of this diseased fluid again upon the nerves ; but it is questionable if the poison first creep in through the blood. Supposing the poison to be in the blood, the spasm and cramp are in the muscles, and this in a ratio with the virulence of the poison. As regards the use of opium, it was found, as Dr Wilson has stated, to be followed by very deleterious effects. Low nervous fever was the result of its em- ployment in repeated doses ; and if the disease were tlioroughly formed, it was never arrested by the use of this drug ; but I must add, that for those uneasy symptoms, which threatened a commencement, a dose of laudanum, combined with an antispasmodic, stood me in much service in my practice. In many, probably in most cases, there was no other disease to combat than the effects of fear, where this antidote proved useful. The patient, attentive to every little pain and ache, was rendered more susceptible of the malady, and the immediate relief afforded him by this diffusi- 188 CHOLERA MORBUS. ble stimulus dispelled liis fears of future consequences. John Brown, one of the brightest but most eccentric meteors that ever illumined the medical horizon, has observed, that no man, however disposed he might be to commit suicide previously, Avould ever think of doing so after a dose of laudanimd, at least while under its intoxicatino; influence He ranked it araono-st the most powerful stimulants. I therefore put all who were in the habit of consulting me, in possession of a " sovereign remedy," in case of need, and I had no reason to repent of so doing. In the treatment of decided cholera, there is at present nothing to fall back upon. The saline prac- tice was not more successful than any of the other modes of treatment. Two cases occurred in the town, and two of the worst that I met with, more than a twelvemonth after the malady had made its retreat. The one was a government courier, an Englishman, who was seized on the road, a day's journey from St Petersburg. He died with all the severe symptoms of the malady. The other occurred six months afterwards. It was the severest case that I ever knew recover. Here the vomiting was the most distressing symptom. The spasms of the diaphragm were terrific, and the efforts to vomit seemed to tear the patient to pieces. Iced water to drink, and ice applied all over the region of the stomach, seemed to afford him the greatest relief. I am not aware of any other case occurring in the city subsequently. I was requested by the police to certify that these were not cases of cholera, for fear CHOLERA MORBUS. 189 of creating alarm with the public from the re-appear- ance of the enemy. None of the numerous attendants upon these two cases had any cause to repent of their charitable exertions ; but the fear of contagion had been pretty well rooted out of the public mind before this period. JNIy friend and colleague, Dr Markus, had worked wonders in this respect. Still more con- ducive to this end was the conduct of the Emperor, who exposed himself at the very acme of the disease to quell a riot, caused by the idea that poison was mixed with the food of the people. His presence on this occasion was more than the tower of strength in a king's name. His manly, intrepid conduct, is worthy of a better chronicle than mine. Several causes conspired to aggravate the panic, which the invasion of a mortal and hitherto unknown disease must, under all circumstances, produce in the minds of uneducated people. Hecker informs us that the first appearance of many of the fatal epidemics which have from time to time invaded Europe, has been associated with the idea of poison, and hundreds of innocent people have been put to death in former times, at the instigation of constituted authorities, and by l^ynch law, upon presumptive evidence, of exercis- ing powers which were the prerogative of the diseases alone in question. In the present epidemic, it was not peculiar to Russia that erroneous ideas possessed the people's minds. When they saw their friends and companions fall suddenly from a state of health into the jaws of death, when they found them attacked at the same time by vomiting, excruciating pains in the bowels. 190 CHOLERA MORBUS. and watery evacuations ; when this was accompanied by a sudden and indescribable change of countenance, their bodies becoming of a blue leaden cast ; and all this within the space of a few hours, such things having never been seen before, it is not surprising that the people were suspicious as to the cause of these strange sights. It happened at this time, how- ever, that the disturbances took place in Poland, and as a mortal hatred exists between the Poles and Russians, many of the lower orders believed that the Polish population were wreaking their vengeance in this way, and this opinion was not confined to the lower orders. As few who were transported to an hospital, survived many hours, the dread of being carried there was extreme ; and as the police had peremptory orders to convey all who were attacked with the complaint immediately to these institutions, — an arrangement which led to great abuses on the score of bribery, some who were ill with other complaints being forced away from their houses against their wills; others, by means of fees, allowed to remain when they ought to have been removed, and, above all, the injudicious autopsies in the hospitals, — all these things combined, worked up the wrath of the people to the highest pitch. It Avas believed by many that the doctors were in collusion with the police, and that they shared the bribes, which were given by those who either were not cholera patients, or, if so, would have given their last piece of coin to escape the hospital. This was proved to be the case in one' wretched instance, where a Jew doctor did exercise such a trade, and being de- tected in the fact, laid violent hands upon himself. CHOLERA MORBUS. 191 A coach driving towards the hospital in the hay- market, was stopped by the populace, owing to the cries which proceeded from within. A man jumped out and exclaimed that he was as well as ever he was in his life, and that they -were taking him to the hos- pital by force. Exasperation was now at its height, and the populace made an attack upon the building. They laid hold of the principal physician, pitched him out of the window, and so maltreated him that he died. Another physician escaped by hiding him- self under a mattress ; and God knows what might not have been the consequence, but for the timely arrival of the Emperor, who, as soon as he heard of the disturbance, mounted horse, and dashing into the midst of an infuriate populace, addressed them in some such terms : — " What is the meaning of this, do you call yourselves Russians ? You are more like . On your knees, this moment, rebellious subjects, implore the pardon of the INIost High, and propitiate his wrath for your ingratitude." This operated like magic. A whole multitude of furious men were prostrate in an instant. The lion became the lamb.* He then consulted the best authorities for information, and as those were times when men dared to speak the truth, he immediately forbade all future interference of the police, and placed the re- sponsibility into worthier hands. This was the termination of all disorders, and no breath of poisoning was afterwards whispered. It worked still farther good, for when the sovereign * I have, since writing this, seen nearly the same statement in Fraser's Magazine, 192 SCORBUTUS. himself was seen to issue more purified from the fur- nace, the fear of contagion was greatly diminished; and as it was impossible to shrink from that which he had braved, the higher orders were found at their posts, visiting the sick, and encouraging the faint-hearted. The nervous system certainly has much to do with cholera. SCORBUTUS. Dr Stevens has rescued salt provisions from all blame in the production of this disease. It is the loss of the succulent matter in the salted provisions which produces the evil. This view is no doubt correct, and the experience of the Canadian fur-traders proves that the absence of vegetable food is not sufficient to pro- duce scurvy, for Sir George Simpson informs me that the boatmen live for months together upon fish and flesh, without tasting bread or vegetables, and enjoy the best health. They are not always furnished with salt. Of animal food they consume an enormous quantity in the cold weather. The late Lord Selkirk, who took a number of Highland labourers to his set- tlements on the Red River, informed me that they ate to the amount of seven pounds of buflfalo flesh per diem per man. The use of flesh had previously, perhaps, been unknown to them in the Highlands. The scurvy, which is considered a disease of the blood, par excel- lence, seldom manifests itself in the system till the nervous power be greatly depressed, of which the Russian expedition to Kiva furnished sufficient proofs, SCORBUTUS. 193 for not a man was affected by it till he was dispirited by retreat, when it made great havoc among the troops. The w^ant of vegetable food is not alone suf- ficient to produce it ; but as mixed food is evidently conducive to the health of an omnivorous animal, this privation may act amongst other predisposing causes. In the nature of all fevers, we witness the effects of the morale both in warding off their attacks or carry- ing the patient through. In the malignant fevers of the West Indies, it has been observed by one of our naval officers, that the crew^s of vessels most kindly treated by their officers are those among which there is the least mortality. When the men are vexed, and harrassed, and punished, for trivial offences, they invariably fall sick. Nothing is more conducive to the health of a crew than keeping them in good humour. Collingwood proved to our navy what could be done by kindness, even consistently with the maintenance of the strictest discipline. So ge- nerally "^^"as this allowed in the fleet, that it was a saying with the officers of other ships, Avhen they had a refractory subject, We must send him to Col- lingwood, he will be able to manage him. It is the duty of us all, in as far as we can, to study kindness in the management of our patients. Tiiey often require it ; and a cheerful countenance, a good humoured address, and a certain method of encourage- ment, are not without their beneficial effects in the treatment of disease. " The very look of him does me good," has been often said of a late eminent sur- geon by many of his patients ; and life may be in the K 194 SCURVY. balance between hope and fear, as inspired by the conduct of the attending physician. SCURVY. There is no better description of this disease than that given by Commodore Anson in his voyage round the world. After mentioning the hopeless state to which his crew was reduced by storms and tempests, and the probability of total destruction, he proceeds to describe the breaking out of the scurvy. Chapter X. " However, though it frequently puts on the form of many other diseases, and is therefore not to be described by any exclusive and infallible crite- rions, yet there are some symptoms which are more general than others, and therefore occurring the oftenest, deserve a more particular enumeration. These common appearances are lai*ge discoloured spots, dis- persed over the whole surface of the body, swelled legs, putrid gums, and, above all, an extraordinary lassitude of the whole body, es^^ecially after exercise, however inconsiderable; and this lassitude degenerates into a proneness to swoon on the least exertion of strength, or even on the least motion. " This disease is usually attended with a strange de- jection of the spirits, and with shiverings, tremblings, and a disposition to be seized Avith the most dreadful terrors on the slightest accident. " Indeed it was most remarkable in all our reite- rated experience of this malady, that whatever dis- couraged the people, or any time damped their hopes, DIABETES. 195 never failed to add new vigour to the distemper, for it usually killed those who were in the last stages of it, and confined those to their hammocks who were before capable of some kind of duty, so that it seemed as if alacrity of mind and sanguine thoughts were no contemptible preservatives from its fatal malignity." DIABETES. Louisa Subiron, aged fifty, of a naturally good con- stitution, and inclined to corpulency, was subject to frequent nervous attacks, which rendered her melan- cholic. She consulted me respecting a disease, which she had concealed for some time, and which the great inconvenience to which it subjected her compelled her at length to reveal. She complained of excessive thirst, which she could not quench ; she drank from ten to twelve pints daily of different kinds of cooling beverages ; she slept ill, and whenever she awoke, her tongue felt so dry, that she could not articulate tUl she had moistened her mouth. The skin was dry and rough, without the slightest moistm'c, which she could not excite by any of the ordinary means. The l)owels were constipated, the digestion weak, appetitq bad, and the nervous system much shattered. She ^vas subject to vertigo, and her eye-sight failed her. Tlie preceding winter she had suffered much from j)ains in her loins Upon comparing the quantity of fluid which she drank with that which was voided, I found the latter to be a sixth part more abundant than the former. 196 DIABETES. She passed about fifteen pints of water daily, Avhich, when analysed by M. Chevreul, was found to contain a quantity of sugar. There were no longer doubts as to the nature of her complaint. I decided upon bleed- ing her in spite of her nervous condition, — the pains in her loins seeming to justify it. Twelve ounces only were taken from her arm ; but she felt much relieved from it ; slept better than usual, and was more gay, and felt lighter; the thirst was diminished, but the skin was as dry as before. I put her upon animal diet, allowing only a small portion of bread and milk, and lime w^ater for drink. Ten grains of Dover's powder were given at bed-time, and she took a warm bath every evening. The urine decreased to twelve pints, and all the symptoms dimi- nished for several days ; but recurring again, although with less severity, I decided upon taking away twelve more ounces of blood. It coagulated more rapidly than upon the former occasion, the crassamentum was firmer, and the serum clearer. She felt immediate relief, and expressed surprise at finding herself stronger after bleeding. Two days subsequently, the urine Avas diminished by a third part. It was of dark colour, had an ammoniacal odour, but still contained much suo-ar. As the functions of the skin were not restored by sudorifics, or the warm bath, and as all hopes of cure were founded upon the restoration of this func- tion, I decided upon employing the vapour bath, and keeping up the perspiration, Avhich I trusted to excite by this means, by violent exercise. She was subjected to a vapour of 45° Reaumur, for the space of half an hour. She perspired pro- DIABETES. 197 fusely, and changed her lineu three times during the evening. She found herself better the following day, but weak. She walked the distance of a mile, warmly clad, and perspired freely. The urine was noyv re- duced to five pints daily. As bad weather prevented her from taking exercise m the ojjen air, and the skin became dry again, the vapour bath was repeated. She could not remain so long in it as on the former occasion, owing to the profiiseness of the perspiration. She was feeble for some days afterw^ards, and per- spired freely without exercise. From this period all the symptoms of her disorder gradually subsided, and the functions returned to a healthy state. She went into the country, where she completely recovered. She once complained of pains in her loins, to which succeeded a diarrhoea, upon the cessation of which she required no more medical interference. Upon analyzing the urine three months afterwards, no ves- tige of sugar was found. — Abridged from Magendie's Journal of Expenmental Physiology, Paris, Xovember 14, 1824. In republishing this case I have had two objects in view, viz. to prove that this affection may be much influenced by nervous derangements, and that such are not always to be cured by nervous medicines ; and to state, that in this case the cure was per- manent. I was enabled to procure every information rcs[)ccting the patient for ten years afterwards, and I saw her again in 1837. She never had the slightest return of her disease ui) to this period, and died of hydrothorax, in her sixty-third year, in Poland. It is 198 DIABETES. true tliat I lost sight of her for the two last years of her life. Dr Bright observes, that the most severe instance of pleuritis which he ever witnessed was in a case of diabetes, where the inflammatory disease carried off the patient in two days. FETERS. 199 PART IX. FEVERS. It would be a laborious task to bring into any mo- derate compass all the different views which havQ been maintained respecting the causes of fever; it will suflSce at present to touch upon such doctrines as seem to be at present reviving and threatening to produce a change in medical opinions. Some works have appeared during the last ten years which savour strongly of the humoral pathology, and none more so than that of Dr Stevens' upon the blood, which, hap- pening to be produced at a time when the cholera was marching througliEurope, excited general and deserved attention ; and we think with the author, that there is not anything derogatory to the dignity of the profes- sion in looking back and halting in our march, or returning again to a belief in doctrines which have been laid aside, provided we have reason to be dissa- tisfied with those which have been adopted in their stead. "To arrive at truth we must lay aside all previous prepossessions, and look calmly but closely at the disease itself." If we meet with error and uncer- tainty in the mazy paths of metaphysical enquiry, there may be little assuredly to excite our astonish- ment, but to find palpable errors handed down from generation to generation, does seem to imply that even common observation rcrpiires a certain time for 200 FEVEns.' its maturity. If Ave seek for the greatest number of such we shall find them among the long recognised and well established facts which have stood the test of time and experience. But let us proceed merely into the physical world, and we shall find that such as required but the use of two eyes for their explosion, have been inculcated by divines, philosophers, and poets, as undoubted truths, and received a sanction which it would have been deemed irreverent to ques- tion. We mount not to the stars for illustration. AVe trudge along the road side — our foot stumbles upon an ant hill. It is painful to be undeceived, and yet all the lessons of our youth, all the moral of the tale, prove but a fable. We have sung hymns to his praise, — we have enjoyed the wit of the littlehero, who, in consciousness of his own thrifty and precautionary virtues in laying up store for the future, tells the famished and suppliant grasshopper to dance through the winter as he sang all the summer. I believe Ileaumur to have been the first to point out this error, though it has long survived him. Yes, says that most acute of all observing naturalists, " Malgre, les belles choses qu'il ne dit a la cigalle," the ant does not hoard up grain nor make provision for the future, about which he is as reckless and careless as the danc- ing chirping grasshopper. It required no effort of genius to make a discovery as available to the clown as the philosopher ; yet from lack of that legitimate curiosity, which consists in the ascertainment of facts, this error has prevailed from time immemorial. The naturalist may have blushed FEVERS. 201 to have been made wise only at the eleventh hour, and the comparative anatomist have reproached him- self for remaining in error when anatomical inspection should have demonstrated that the mandibulary organs argued the carnivorous nature of the insect. The nerves were formerly considered as tubes which conveyed a subtile fluid too fine to be recognisable by our senses ; still the doctrine of a nervous fluid was long prevalent, and was only abandoned as being untenable upon demonstrative evidence ; for neither could the naked or assisted eye discover this tubular structure. The doctrine of vibrations replaced that of undulations, and the nervous animal was compared to an ^Eolian harp, the nerves being mere chords like strings of cat-oTit. It was not upon demonstrative evidence that the one theory was maintained, as it has since been proved; AVas it upon demonstrative evidence that the other was adopted in its place ? Our demonstrative evidence, therefore, about which so much is said is but relative after all, nor do we sit safely or even long together upon this stool. If demonstration placed us there it pushes us off" again. To reject Avhat is not demonstrable to our senses is but poor philosophy, seeing that we are often led astray when we trust to their guidance. We now find that the nerves are really tubular, for our eyes being better assisted, they can see fartlier into things than they did before. It nmst be remembered, however, that it was upon microscopical evidence that we decided against the doc- trine of a structure which we now rccoj'nise to be true 202 FEVERS. In fact we may consider ourselves still upon our journey ; we have been twice unable to proceed in our route. In the first instance we were in the right path, but the way was so obscure that we could not proceed safely. In the second, an ignis fatuus led us astray — took us completely out of the narrow way, which was as usual also the straight one. Some steadier star has conducted us once more into the old track ; whether it Avill remain stationary and aflbrd us light enough to carry us through, or fall meteor like, and leave us in the dark again, is still to be seen. We can seldom say more than this in all such in- quiries. We have seen as far as our present means will alloio us to see. We cannot say that /mother means shall not be afforded us. We have a great deal of curiosity, and still our eyes are very had. The nerves are again recognised as tubes, and found to contain a fluid, so that we return again to our old schoolmaster, nor do we blush to do so ; and if other antiquated ideas turn out to be correct, none ought to hesitate to reinstate them in the ranks from which they have fallen back. " If we gain by going back, the sooner Ave return, the better it will be both for the sake of science and the cause of humanity." — Dr Stevens. The original and very valuable researches of Dr William Stevens, on the physiology and pathology of the blood, supported as they are by experiments and practical results, will constitute an era in the history of medicine. The almost forgotten experiments and observations of Boerhaave, Huxham and Haller, have thus been incidentallv revived, and clothed with a new FEVERS. 203 and Important interest, by the aid of modern chemistry. A spirit of liberalism is the offspring of enlightened science, and weighs the value of discoveries by their intrinsic worth, from Avhatever quarter emanating — allows for the errors of persons unversed in the tech- nicalities of the schools, and honestly and carefully separates valuable facts from trivial inaccuracies. Such a spirit, while it conduces to the progress, regu- lates the march, of truth, and preserves us from the danger of relapsing into the solidism or humoralism of our predecessors. With every appreciation of the claims of Dr Stevens, it is impossible to overlook the fact, that his views of the importance of the blood in the economy, lay him open to the danger, if not the charge, of exclusivism, which he so much deprecates." — Travers's Inquiry into Constitutional Irritation, p. 217. " As a general rule," says Dr Stevens, " fever or febrile diseases may be divided into two great classes. First, into those which do not arise from any of the aerial poisons, but depend entirely upon other causes ; such, for example, as cold-checked perspiration, long continued excessive heat, local inflammation, &c. Secondly, into those which do not arise from any of tliese causes, but are produced entirely by the intro- duction of some deleterious poison into the system. These two classes are totally separate and distinct from each other." Notwithstanding this difference, the fevers of the first class assume, under peculiar circumstances, all the malignity of the latter, as the typhus wards of hospitals too frequently demonstrate. 204 FEVERS. As regards those which are tlie result of poison to the system, Dr Stevens observes : — " The most con- centrated poisons never produce fever in less than forty-eight hours — there is not one single exception to this rule — even the poison of cholera, never less than two days from the time it is taken into the system." All those cases, therefore, of " deadly fevers being kindled up in the course of a few hours, proving that the nervous system is the first to feel the influ- ence of the cause of fever" — all such histories are treated by Dr Stevens as mere " romance, and as untrue as the Fables of .Esop."— P. 232. If this applied exclusively to the fevers of the West Indies, our experience would not be of any avail upon the point ; but in limiting the poison of cholera to two days, if this be proved correct, it is fotal to the doctrine of this disease being communicated solely by animal contagion, for our own experience and obser- vations can warrant the assertion, that in the city of St Petersburg it appeared in the most wide spread quarters of the town, Avithin twenty-four hours from the first recorded case, by which it could not, there- fore, either directly or indirectly have been propagated'. " The cause of all malignant fevers is attributable to a poison decomposing the sahne matter of the blood,, and all consequences upon the solids produced by diseased blood itself. The objection to nervous im- pression as a cause of fever is this, that all impressions ujion the nerves produce an inimediate eiFect ; thus, v,hen light strikes the eye, the impression is imme- diately conveyed to the brain ; whereas, these poisons may lie dormant days, weeks, and months, before they FEVERS. 205 pi'oduce fever, and create the cold stage which is caused by the loss of power in the heart, poisoned by the blood."* This reasoning can only hold good upon the sup- position that all the authority extant for the belief of fever being caused by sudden influence upon the nervous system, is to be treated as romance, and as a fable of ^5^sop's. '' A vitiated state of the blood producing functional disease in all the solids, derangements in all the secre- tions, and sudden variation of temperature, not merely of a part, but in the whole system, is, as I believe, in every instance the very essence of fever." I'his is applied by Dr Stevens to fevers generally, and not to those peculiar to the West Indies. Dr Billing, in his Principles of ^Medicine, maintains opi- nions diametrically opposed to those of Dr Stevens. In idiopathic fever, the lesion of the nervous system is, in fact, the local disease. It is, in my opinion, the nervous system itself, which, being injured, produces synocha or inflammatory fever, as it arises in hot r-limatcs, and in this country in the heat of summer, in labourers exposed to Avork under the heat of the sun, or some times from the opposite cause of excessive cold, combined with deprivations, excesses, depressing passions, or other causes of injury to the nervous system, by infection or epidemic influence, as is the case in the synocha i'>etechiuUii." There is some thing to us much more intelligible in this theory, more consonant with tlie whole train of symptoms, as they usher in the disease; more con-- * Si!e Appendix, 20G FEVERS. sistent Avitli such as develope themselves dunng its progress ; more explanatory of those causes which pre- dispose to it, as of those which maybe said to be morally prophylactic ; more certain guides to the forming a prognosis of its issue, and more indicative of a rational mode of treatment, than in the supposition of the blood being the primary offending agent. In the first place, a sudden shock to the nervous system has produced fever instanter ; and Dr Copland, wlio is well versed by experience in fevers of other climates, states — " When the infecting agent is intense, as when a concentrated animal effluvium, or an accumulated emanation from the bodies of the sick, is directed upon a susceptible person, then the effect may be instiDita- neous as eleetriciti/, as well as most intense. In some rare cases of this kind, as in plague and in other pes- tilential maladies, life may be destroyed in a few hours by the morbid impression which it has been quite incapable of opposing, and against which it has been unable to re-act. I have seen the emanations from typhus fever, from yellow fever, and from pesti- lential cholera, immediately produce sickness, vomit- ing, pain, sinking, and anxiety at the epigastrium ; faintness, oppression at the chest, remarkably weak pulse, headache, and general vital depression, with pale countenance and shrunk surface, and from these the patient has never rallied, the symptoms increasing in severity, and others supervening, until death has occurred in a few hours." — CoplancVs Medical Diet., p. 355, Part VI. In further illustration, regarding the manner in FEVERS. 207 ^^■hich infections invade the economy, and their im- mediate or direct effects, the same author observes, — " That certain infectious agents impress the organic nervous system directly and chiefly, is shown by the suddenness of the effects, by the sensations experienced at the time of exposure to those agents, especially to emanations conveyed in the air, by the sense of con- striction and oppression produced in the chest, by the frequent and forcible efforts made to dilate or fill the lungs, as if the impression of the infectious emanation had impared the vital resiliency of these organs, by the offensive odour frequently perceived at the time of infection, by the sickness, fear, and alarm instantly afterwards felt," &c. We must all have had opportunities of hearing patients say, and particularly students in fever wards, that they knew when they took the fever, — they felt it at the time. It is evident, therefore, that the nervous system is the first affected ; and in the progress of the disease, its powers becoming less and less, the blood no longer receiving the same stimulus from it, is affected sub- sequently. " It is difficult to ascertain the state of the blood at the commencement of these fevers, for most of them preclude its abstraction. In some few cases, where blood has been submitted to examination in the early stages, its appearance indicates rather the vital conditions, derived from the organic nervous system supplying the vascular system and vital organs, than any change in its chemical constitution." The blood's vitality is due to the nervous fluid, (a term which recent experiments allow us again to 208 FEVERS. employ) ; but tliis vitality is necessary to stimulate that very system to clue action which supplies the means, and hence their mutual dependency. The blood is no longer nutriment to the nervous system when deprived of its invigorating principle ; and it degenerates, pari passu, with the loss of nervous energy, till it becomes a noxious decomposing mass, as it is found congested in the organs. " The ex- haustion in these diseases arises from, 1st, The pre- vious excitement ; 2d, From the changes induced in the course of this stage, especially at its acme, mani- festly depressing the organic nervous influence, the tenacity of the vascular system, and the action of the heart itself" The power of certain salts, particularly the muriate of soda, the nitrate of potash, the tartrate of potash, &c., as well as of the alkaline carbonates, to render the nervous blood florid, and to effect its fluidity and coagulating powers, was long since demonstrated by Verhugen. — (VoL ii. p. 29.) It is upon the decrease of saline matter in the blood that Dr Stevens founded his practice of administering the alkalies in the treatment of these fevers. " The fact, however, upon which it is based, has not received that confii-mation for which there have been time and opportunity." " The characteristic phenomena of the last stage, the hemorrhages and discoloured blotches, are manifestly owing as much to the exhaustion of organic nervous influence, and of irritability, as to the attendant changes in the blood." These changes are attributed by Dr Stevens to the loss of saline matter, and " the basis of the pathology and treatment is the FEVERS. 209" relation subsisting between the colour of the blood and the saline matter contained in it." But granting that the colour of the blood is changed to its healthy state by these salts, it does not follow that they shall be absorbed into the circulation during the advanced stages of this fever, or that they shall have the effect of rallying the exhausted powers of life. As to both these circumstances, the sanguine expectations of Dr Stevens require confirmation." " The curability of any given case is in a great degree determined by the amount of their primary actions on the brain. It matters not in a practical point of view, whether the brain and other vital organs are primarily or secondarily affected ; that is, whether contagion acts immediately on the nervous system, or mediately through some preliminary con- tamination of our fluids, the result is the same." — Sir .1. Chrichton, p. 120. A convincing proof that the blood is not the first offended in fevers is the condition of the blood itself; for if it be di'awn in the onset of many fevers, it is not so much altered as to manifest any change commen- surate with the effects already produced. It is always in precise ratio with the deterioration of the nervous energy that the blood developes its morbid state. " The occasions on which the blood seems to be more inxmediiitely contaminated by infectious agents, are, first, when a specific virus or morbid secretion is in- serted into a wound, or beneath the cuticle ; and, secondly, ^vhcn putrid or septic matters are similarly applied. The period which elapses between the ino- culation of a specific virus and the development of 210 FEVEns. the constitutional affection, however, by no means shows that the immediate operation is upon the blood, and that this period is required for the production of morbid changes in it. That the organic nervous system is the chief channel by which the first change induced in the part is communicated to the whole body, is shown by the circumstance of the constitu- tional effect being frequently as great Avhilst the local change is slight, as afterwards when it has become fully deYe\oi^e(\r— Copland, p. 357, Part V. From local injury to nerves, as in cases of amputa- tion, fever is sometimes set up, and assumes a typhoid form. How it progresses in local inflammation is well expressed by Mr Travers. " The setting up of fever is gradual. It is not esta- blished under many hours more than local inflamma- tion ; so is the alteration in the properties of the blood which induces it, so are the changes to which it gives rise. Whether the first morbid impression and action be upon the nervous system, transmitted by the nerves of the part injured, or inflamed to the nervous centre, and thence to the organs of circulation, is a moot question. To my mind, the pathognomic signs, as well as the facts of physiology, are in favour of this opinion. The premonitory symptoms, viz. headache, lassitude, disquietude, nausea, chilliness, and rigour, are indications of the more or less troubled condition of the nervous centres ; to these the alteration in the measure and force of the circulation, the permanent and sensible changes upon the internal and external surfices and their secretions, succeed, viz. quick pulse, hot skin, dryness of mouth and fauces-furred tongue. FEVERS. 211 vitiated and scanty excretions, &c. Of the cliangcs that ensue in the parts which are the seat of inflam- mation, we sliall speak in another place ; but that the action of fluid and sohd is reciprocal in the production of inflammation and fever, as it is in the functions of health, and that it is inconsistent with all we see and know of the animal functions ; to imagine the possibility of either being exclusively in fault, is a })roposition which scarcely needs to be exemplified.'' — Travers on Inflammation and the Healing Process, p. G2. The poison of malaria may remain sometime in the system before it manifests its effects. It may be in the blood, A^hich is doubtful ; but when it passes from a latent to a free state, its first offence is to the nerves. These fevers are styled by the Germans masked inter- mittents ; and as they prevail, wdiich they do very much, in Vienna, the German practitioners are very cautious about bleeding in the first stages of synochus, lest the mistake shoidd prove fatal, and the fever unmask itself I had a very marked case of this kind in St Petersburg. A gentleman whom I had often seen and attended, arrived as courier from some of the swampy districts of Turkey. He sent for me in the evening, and, ob- serving him to be in a very nervous state, and much agitated, which, however, I attributed to a very forced march, I ordered him a warm bath, and a sedative. The following day he was somewhat calmer, but there was an indescriljable something in his manner, Avhich I coidd not understand, lie said he thought his liver was out of order, and felt his side, and walked very (piickly up and down the room. I prescribed some 212 FEVERS. colocynth and calomel, and left him for the night. I was sent for early in the morning by the people of the house, who informed me that the gentleman was out of his mind. I found him in the state they described, and had leeches freely applied to his temples. The whole of this day and the following he remained mvich in the same state, more quiet, but talking incessantly about his family and his affairs. He took a large dose of morphine in the evening, and the following day he was more composed. About eleven o'clock a.m. I was sent for to him, as he was supposed to be dying. I found him as black in the face, and as cold to the touch, as in the last stage of cholera. His teeth chat- tered in his head, and the very bedstead shook under him. I immediately recognized his malady, gave him a tumbler of hot brandy and water, and ordered him ten grains of quinine every four hours. He rallied, and at night took a grain and a half of morphine. The next day another fit, about the same time, but less violent, attacked him. I plied him freely with bark, wine, and opium, and in a week he was convalescent. I have had the pleasure of seeing him since I returned to England, and he tells me he has enjoyed excellent health since. Now, I have little doubt, but that he brought this malaria with him from Brailoff. It must be remtjmbered that Dr Stevens maintains that poison in the blood is the cause oi all fevers. It is not to those of the West Indies that he confines himself. Now, we cannot recognize it in those we have seen in this country, not in the one which at- tacked us so severely in the fever hospital of Edin- burgh, when we dreamed for nights and days that we FEVERS. 213 were rowing in a boat ; and when, during convales- cence, neither country air, nor exercise carried to fatigue, would allow us to close our eyelids for weeks. We Avere in a state of nervous tremour all this time not to be described, but of which the recollection will never pass away. During our Russian medical cam- paign, in the fevers which we treated, in which, for the most part, cold and the abuse of spirituous liquors were the exciting causes, we found no reason to abandon old ideas upon the subject, and we can subscribe to the assertion of Dr Billing. From the very nature of fever, Avhich I have de- scribed to be a disease essentially affecting the nervous system, it follows, that the functions of the viscera must be disturbed ; and though, as just pointed out, sometimes disease of one organ predominates, some- times of another, yet every organ suffers more or less congestion in every fever from the loss of nervous influence The phenomena of idiopathic fever show that the nervous system is first implicated, dcbihtated by a mor- bid poison from the first ; and Dr Billing asks tlie ques- tion, "But how is it to be known when the fever was gone?" which he answers, " By referring to its essence the loss of function of the nervous system. The fever is gone where the nervous system begins to regene- rate nervous influence, — when the intellect becomes clear and volition free, however weak, .... for subsultus may still remain, and other marks of great debility, and there may be debility of brain, amounting to childishness, but delirium is gone, and the eye ioUuws objects. Patients themselves can often refer 214 FEVERS. to the exact time of tlic fever passing off." — Billing's Frinciples of Medicine, pp. 179-18G. IMost have had opportunities of sympathizing with patients under this latter circumstance, — the very look is sufficient, on approaching the bed-side, to convince us that the fever is gone. There is often a beautiful expression of the eye, — a tear steals into it. We would almost judge from the look that it is one of gratitude to a supreme power. I was once much struck with this when attending some invalids during the siege of Varna, Avho had come to Odessa, where I was staying. A Russian general, who had been ill for about a fortnight with continued fever of no very severe kind, exclaimed, as I opened his bed-room door in the morning. Doctor, my fever is gone, it went away in the night, and I went to sleep. He was convalescent from this time. We cannot altogether pass over the influence of moral causes in producing and aggravating fever on the one hand, and rendering the system insusceptible of it, and can-ying the patient through, on the other. Mrs Quickly, in alluding to Falstaff's fever,* for it was one of which he died, — he was " shaked by a burning quotidian tertian" traces its origin to this cause, — " The king has killed his heart." Here was the fatal blow, — the sorrow that worketh unto death, — wearing the system out by slow poison to the nerves, and degenerating into fever. The gra- * In this view Falstaff is not an imaginary being. The man living upon the smiles, anrl pining away upon the frowns, of court, is a sad but not single reality, and, as such, worthy of pathological inquiry. FEVERS. 215 dual loss of the nervous power is traced >vith graphic accuracy. AVe find it failing physically. His friend Bardolph's nose, studded with carbuncles, misled his failing visual j^OAvers into the belief, that a flea was sticking upon it. Then the mental powers failing him, he (the ruling passion still strong in death) talks of sack, but " After I saw hira fumble with the sheets, and play with the flowers, and smile upon his fingers' ends, I knew there was but one way with him ; for his nose Avas as sharp as a pen, and he babbled of green fields." The occurrence of fever in a sporadic form leaves room for conjecture, as the term predisposition offers matter of controversy, for we cannot tell a priori that predisposition exists ; and not until the disease has manifested itself do we conclude, at least in many cases, that it did. In passing a regiment in review previous to marching it over the Pontine Marshes, we should not be able to pick out the men who would be attacked by malaria, presuming all to be in good health at the time,forone disease invites to another, and Avhat- ever renders the nerves weak renders them susceptible of impression ; yet, as soon as the man falls down, we say he was predisposed, though Ave Avere unable to say so before hand, and, if Ave had passed judgment in the case, might have erred as to the individual. It is a facon dc parler, and is often an instance of the sub- stitution of Avords for ideas. In adopting the views of those Avho place the first stroke of fever in the nerves, it is much more easy to understand the terra predisposition and its conse- quences ; for, in this vicAV of things Ave have a chain of 216 FEVERS. moral causes continually operating, -svhich act upon these organs. We have seen that moral emotions change the healthy states of the secretions throughout the system, for which the integrity of the nervous influence is requisite. A stronger dose of this moral poison prostrates the man and engenders fever ; now, whether it be possible for a man to fret himself into a fever is a question which many will perhaps dispute, but there is no cause or impediment against such an occurrence. Moral causes continually acting upon the nerves deprive them of their energy, and the blood and secretions by degrees feel this deterioration, become more and more unfit for the purposes to which they are destined, and losing their vital properties cease to impart them; hence they become offending agents, and may be themselves the causes of fever. There is phy- siological as well as moral truth in those lines of Byron, alludino- to blighted ambition and reverses of fortune. It has been the lot of many, as of our fat knight, to be " The sword laid by That eats into itself and rusts ingloriously."" ''^ This fever at the core" does prey and prey upon the system till all healthy action ceases, and morbid con- ditions arise which finally threaten feverish exhaustion. We may suppose Falstaffareal character, and find no better illustration of these views than in his whole history. Broken hearted, disappointed, removed from the scenes of all his former joys, hopeless of their return, finding him upon whom he had rested the broken FEVERS. 217 reed, deserted by tlie man whose frown was noAv death, as his smile had been life, to him, banished even from his atmosphere, rusticated upon a pension granted him Avith the galling moral that he might have wherewith to live and not be tempted to do ill, he was left to himself to brood over his mis- fortunes, to recognize his impotency, to find no sym- pathy, to be pointed at and held up to shame, to he trodden under foot. He was as morally dead as Yorick was physically. He had no courage left, no moral energy, and then his physical nervous powers Avould fail him by degrees. The sack would no longer rouse his spirits though it might drown his cares for the moment. His heart was killed. Here, then, we might presuppose predisposition, and what more likelj than to find his death in an aguish fever.* Of all predisposing causes, in the general acceptation of this term, Avhatcver depresses the nervous energy is by aU considered as the most important, whether from the physical effects of heat and cold, fatigue, hunger, or the moral effects of anxiety. Of all the prophylactics none is equal to moral energy and moral courage. Of this the plague affords us the most striking examples. Nowhere are the fatal * Af^ues often arise from cold damp air, and now and then from a cold east wind alone, and often from great and sudden distress of mind alone, of wliieli / fiuve seen iico aises, and more are mentioned in the annals of medicine. — Sir A. Cliricldon, p. 126. In a patient lahouring under severe symptoms of incipient fever, showing itni'lf in extreme lieat of the skin, of the head and neck, a very quick and full pulse, and a violent headache, 1 have seen all the symp- toms nearly removed in a few seeon<ls by the moral operation of fear. — Parry' i Elcm/'ida, L 218 FEVERS. eflects of fear better or more beautifully recorded than in the plague of Athens by Lucretius : — " lUud in his rebus miserandum magnopere un um ^■Erumnabile erat, quod, ubi se quisque videbat Implicitum morbo, morti damnatus ut esset, Deficiens animo mocsto cum corde jacebat Funera respectans, animam inmittebat ibidem." The plague of Marseilles furnishes us with an in- stance of individual heroism, Avhich contrasts well with the above. So dreadful was the mortality, that the dead were left to bury their dead. No one was found with courage enough to drag away the corpses, till an opulent citizen boldly sallied out, laid hold of the bodies with his own hands, and by his example inspired courage into the souls of the most timid, who rallied round his standard, and cleared the ground of the putrid carcasses ; nor is it recorded, that any one thus inspired was infected by the disease. It is difficult to understand, by any other rationale than a certain degree of courage or confidence in the individuals, the dogma that exposure to disease renders the exposed less susceptible of its influence. This ia decidedly a sophism. If the same susceptibility exist the frequent intercourse with the diseased can only increase the danger ; but the fact is, that fear being conquered by the first escape, the susceptibility of impression is diminished. Physicians and nurses do fall victims to infectious diseases, but not in any ratio with the amovmt of their exposure ; and although the average of medical life is very low in the scale, still it is high in consideration of the degree of exposure, if there were not a controlling power which diminishes impression ; we find it in the moral acting upon the FEVERS. 219 nervous. Thus the dread of evil is sometimes greater than the evil itself. Of this the cholera afforded us a good illustration. AVhen it was raging at jSIoscow, we of the faculty greeted each other in the streets of St Petersburg with very lengthened faces ; but as soon as it came among us, and we plunged in medias res, there was no fear apparent. The stimulus of exei'tion to vie with each other in finding some reme- dial means, became a buckler to ourselves. The fever in Edinburgh in 1818, to which I have alluded, afforded a very striking evidence of the effects of moral depression upon one individual, who was superintendent of the Queensberry House Fever Hospital. He was the most active man in the insti- tution, and escaped the fever, when all the medical inmates, myself among others, had ])assed through the ordeal. Pie seemed proof against its influence. But he wrote a book upon the subject, — a large volume, and embarked all his little means in the speculation. It turned out unfortunately for him, and preyed upon his mind. He took the fever when the wards were almost cleared of it, and, though he struggled through it, he died of its consequences. I thinkthatsuchinformationas the following has sad- dened the heart of many, upon inquiry after old acquain- tances : — " He got wrong in his affairs, was harassed by domestic misfortunes, got into a low nervous state, caught cold,which terminated in fever, of which he died." Sporadic fever generally singles out the nervous and iri'itablc. The following case, which was one of great interest throughout its whole course, occurred to me in St Petersburjj : — 220 FEVERS. A gentleman of very nervous temperament, and for some time previous in a state of irritability from a variety of depressing causes, having but a few months pi'eviously suffered very severely from spasmodic cholic, and whose digestive organs were seldom in good order, awoke in the morning with sense of Aveight in his head, and a general feeling of languor and debi- lity. He was determined to make an effort to shake it off; and after an early dinner, set out to take a long walk. Upon his return he felt his headache much increased, he was cold and chilly, and went to bed. I saw him the same evening, and prescribed an emetic. It did its duty, but did not relieve him ; he passed a restless night, and the following morning I found him feverish ; his tongue foul, and pulse quick, but rather feeble. I prescribed a brisk dose of calomel and colo- cynth, and gave him salines, with nitrate of potash and antimony. The bowels were opened, but there was no marked relief; and when I saw him in the evening he complained of intolerable pains in his loins, causing him to groan. His morale was already much depressed, and he augured ill of himself. Twenty leeches were applied to the lumbar regions, and a considerable quantity of blood was lost. He had some sleep during the niglit, and in the morning the muscular pain Avas much reheved. Saline purgatives were continued; the urine was scanty but limpid ; the skin and pulse not changed. The body Avas sponged Avith vinegar and Avater, and some leeches applied to the temples ; the headache Avas only severe upon moving it from the pillow. On the fifth day he bcca-ne incohe- rent, and slightly comatose, with some twitching in FEVERS. 221 the muscles of the hands, as he was drowsy and unable to lift up the eyelids. The heat of the skin was increased, the pulse quick but feeble ; the bowels had been freely evacuated. I requested farther assistance ; and Sir AYilliam Chrichton met me on the sixth day, when small petechias appeared all over the surface. The delirium was on the increase. We prescribed a warm bath, with ice on the head during the immersion of the body. This was accomplished without producing any decided effect. A mixture of equal parts of infusion of valerian, and camphor mixture, Vvith spt. of mirdererus, was given every three hours ; tlie sponging of the body was continued, and no change Avas made in the practice, nor did any occur in the state of the patient for two or three days. He seemed always dosing, and was quite deaf; still he could be roused to take his medicine, and he motioned for the lu-inal and bed-pan. The petechia? increased in size. Upon the tenth day we commenced by giving him fhamjjagne every two hours, and he took a bottle In the twenty-four. Tlie nervous symptoms rapidly increasing, fine old sherry A\as poured down the throat, and this alternated with bark and ammonia. Upon the fourteenth morning, I observed for the first time a slight cloud In the urine ; towards evening the lower jaw fell, and his mouth was thrown into continual contortions ; there was great subsultm tendinum. Musk was forced down the throat with some difficulty, 'i'lie animal heat still kept up. Sinapisms were applied to the calves of the legs. I lis friends left him In the suppfjsition tliat he was In the agony of death. I had observed in the morning that he had made a rotatory 222 FEVERS. motion with one hand round his head. The respiration became more laboured as the night advanced, and all the symptoms aggravated. Towards four o'clock in the morning of the fifteenth day, the nurse came to me as I was lying upon the sofa in an adjoining room, and told me that, in some effort which she had made to move him, he had suddenly opened his eyes and spoken. Upon going to him, I found perspiration on liis brow, the respiration was more calm, the motion of the jaw had ceased, but there was much twitching of the buccinator muscles. He was asleep. I remained with him for some time, when he again opened his eyes ; he recognized me, called me by my name, and asked me where he was. I gave him some more wine, and he again slept. He woke into convalescence. He recollected nothing that had passed for the last ten days. His cure was slow, being protracted by large sphacelus of the back and nates. The impression of my colleague and myself was, that if we had bled him from tlie arm, he would not have recovered. There was no fever in the town at the time. Whe- ther it be considered that the brain or ganglionic systems were offended, the case must be referred in its accession and in all its course, to lesion of the ner- vous system. "In the symptoms which usher in fever, the languor, lassitude, decreased muscular power, in the moral effects Avhich predispose to it or resist its attack, in the train of symptoms which develope themselves in its pro- crress, in those Avhich precede its termination, when this is fatal, or in those cases where we see it sua- FEVERS. 223 deuly disappear or gradually dissolve away, we seem to recognize its nervous character." As soon as the brain is enervated to a certain degree, by the action of contagion, or of any of the common causes of typhus fever, the heart, stomach, liver, and all the organs of secretion and excretion, are also disordered, though at first in a slight degree in general, when compared with what takes place in the course of the disorder. These affections of the heart and other viscera, do not follow each other like a series of causes and consequences, as is the case in the subsequent stages of fevei*, they are at first simultaneous phe- nomena, showing their dependence on one common cause. Upon this view of the subject, Sir Alexander founds his plan of treatment : — " Keeping in remembrance the facts previously enumerated, that the chief action of the common causes of typhus fevers, is on the brain and nervous system ; and knowing by experience, tiiat we do not possess a remedy by which we can restore its lost energy, except through the medium of the heart's action and the functions of the digestive organs, we ought to direct our chief attention to them in the first instance." * In the effects of lightning we find the blood killed by the shock, yet this is through the nerves, and the same efi'ects may be produced in the same way from the injection of poisons. Still the death is never so immediate when tliis means is employed — there is time for the transmission of the poison through the * Commentaries, Sir A. Chrichton, pp. 1U5, 123. 224 r'EVERS. whole nervous system, whereas the immediate death of the blood must cause instantaneous cessation of the heart's action. Sir Alexander Chrichton has, in his late work upon fevers, fully maintained the doctrines of nervous influence, and his long and successful career entitle his opinions to full consideration. There is great truth, that sporadic cases of fever are quite as severe as those traceable to infection — and these may be pro- duced by causes which admit of no primary poison. " To attempt an explanation of the nature of nervous energy, or to conjecture how it is formed, accumu- lated, or renewed, by living medullary matter, is perfectly idle in the present state of our information ; but so much we know by observation and experience, that it is a motor force to other livins; organs of the body, and that the functions of such organs depend on its regular supply ; that they are active and healthy, when it is abundantly and freely supplied to them, that they are weak when it is scantily distributed, that they are interrupted, when it is interrupted; and, finally, that they terminate when it ceases to be formed or distributed." It is not to be denied that the fluids and the blood are implicated in the progress of fevers ; and Dr Stevens has called the attention of the profession to the morbid state of the blood, to which he directs his treatment. The solids do not enjoy the preroga- tives of vitality alone, nor are they alone oflfended in disease — for as Miiller has observed, these solids contain a great portion of fluid in their composition, viz. four-fifths. AVe cannot suppose that vitality is im- parted to the solid at the moment of its separation, or FEVERS. 225 in its transition from the one state to the other, as John Hunter has long since made evident. From what we know, however, of the nervous system, seeing as we do, that the slightest local lesion will be followed by constitutional fever, and as we find that direct application of poison to a nerve, is productive of more decided action than w^hen the same is introduced into the blood, except when this carries it to all the system at once by means of the circula- tion ; and finally, when it is proved that a muscle whose nerve is divided, does not participate in the spasm of its colleagues, when this mode of operating is adopted, sufl&cient evidence seems to be afi^brded, that all the effects produced upon the blood result from primary injury to the nervous system. It is not evident that the blood is killed by the in- jection of poisons, till it has carried these into the nuiscular and nervous tissues, when the latter may be so injured that the blood shall participate in the injury. 22 G ]^IALAKIA. PART X. ill Health — Nervous Coughs — Blood to Head — Ague — Molda- vian Fever — Local Diseases of Nerves — Sciatica — Iritis — Knee — Earache — Affection of Jaw. MALARIA. The late Dr Macculloch has considered this poison to be a more prolific source of disease than most of his contemporaries are willing to admit ; but that much more is attributable to it than meets with general belief^ is, I think, demonstrable. I have seen malarious dis- ease in its most severe forms, and in its milder ; but, as far as treatment is concerned, in its more obsti- nate character, baffling the skill of medical interfe- rence, and yielding to nothing but migration from it? locality. The first steam-boat which leaves the Neva upon the breaking up of the ice, affords an annual proof to the faculty of St Petersburg, that a great number of patients who have defied their skill for months, will shake off their diseases in the voyage, and most of them will not require any more medical assistance as soon as they ha-^e put foot on another soil. Situated in a bog, surrounded by march and peaty i^IALARIA. 227 formations on every side, the city of St Petersburg rises a monument of the triumph of art over nature. It was as great a feat for Peter the Great to erect his capital iu such a situation, as for the Roman emperor to conquer the sea by his bridges. It was determined by the savants in Paris, when they discussed the causes of the black death, that if the disease had oc- curred in Sardinia, not a soul woukl have been left alive, so much did they attribute to local influence in the creation of that epidemic ; and were it not for the hard frosts in winter, malaria would probably destroy the population of St Petersburg. Whether the cause of intermittents be attributed to a specific poison, or may arise from other circum- stances, it will be referred by most to a baneful impression upon the nervous system. If there be any disease, both from its mode of attack, and through its whole course, especially as regards its treatment, and the innumerable means which have succeeded ill curing it, that can be denominated nervous, this is the one par excellence. Previous to coming to this point, it will be permitted to make some ge- neral observ^ations on a state of ill health and local affections which circumstances of situation allowed me to witness, and which I refer, with Dr INIacculloch, to the pernicious influence of malaria. The protean form which diseases arising from this cause assume, was then made known to me practically; but it was, unfortu- nately, a knowledge of the causes upon which they dei)cnded, rather than of any successful mode of treat- ing them. Of some of these I shall noAv speak. To many, i^robably, I have nothing new to oft'or. I detail 228 MALARIA. merely the experience of fifteen years' practice in difterent parts of the llussian empire. It will be for others to determine whether it pi^esents anything so novel as to be worthy of special record. " The disorder may be found, and not unfrequentlyy Avith scarcely any marked symptom, except mere muscular Aveakness, — a debility on any attempt at exertion which seems unaccountable, inasmuch as it occurs in persons even in youth, and apparently strong, and is not very obviously accompanied by any proper febrile symptoms. At times not even the appetite seems affected ; and here, almost necessarily, the result is to suspect the state of the patient's mind, or his moral dispositions, rather than his health, to suppose, for example, that a soldier is shamming, that an opu- lent female is indolent or aftected, or a studious or professional man hypochondriacal." This is the character of the slow fever, the fever on the nerves, which lasts for years, with certain inter- missions, but never allows the patient to enjoy good health. It has occurred to me after having in vain essayed to relieve this state, to find that the patient has suddenly been seized with an ague fit, and the character of the fever has thus become developed. There is an observation, also, which applies to these cases, and to others of the same family, and especially nervous spasmodic coughs, which I remember to have seen confirmed by Dr Holland, viz. that the disorder wears away as the day wears on, and in such cases (the sequela of influenza), where there was even pain in the chest ; but where the pulse permitted it, Dr II. told me he prescribed quinine with the best eftect. Dr MALARIA. 229 Maccullocli observes, tluit midnight is the nervous patient's holiday. Although it is generally admitted that no patient Avith real organic disease feels better at night, the reverse being almost always the case, yet this general nervous derangement is an exception to this rule. The Germans insist, that in a state of health, there is always at midnight a revolution in the system, pro- ductive of a degree of nervous excitement. It is decidedly true, as regards these complaints, and hence the little compassion which nervous people meet with, and the construction put upon their com- plaints, as whims, vagaries, nervousness, being syno- nymous terms with many, because these people are found to enjoy society, to be brisk in the soiree, to I»lay their rubber, or enjoy the opera. How can they who seemed so well-last night be credited when they are found groaning under a load of nervous oppression in the morning ? This state, which permits still of alle- viation from social means, might otherwise become more aggravated, and other symptoms arise, which might lead to the conclusion that caprice was bordering upon insanity. " Whatever be the causes," says Dr Maccul- loch, " it is a fact well worth recording or recollecting, that some of the most remarkable suicides have been committed on rising in the morning and in a certain paroxysm of fever, which many persons who ha\e fc'lt and checked that inclination, have described as attended with confusion of thought, thirst, tremor (>[' the hands, and other unequivocal symptoms of fever."' If it be asked how far autopsy assists us in the recog- 230 MALABIA. nition of these diseases of the nerves, Vve must answer that our means of detecting alterations in structure are not sufficient in our present state of knowledge to permit us to recognize any physical alteration. The severest and long protracted torture of a facial nerve shall leave no signs of physical affection. Dr Wilson has brought forward several most in- teresting cases of fatal apoplexy arising from renal disease, where there was " no lesion of the brain, and no effusion on its surfaces or into its ventricular cavities. The fits and all other symptoms in this case terminat- ing by death were, in my opinion, consequent on dis- organization of the kidney, urine was not secreted, the blood was not elaborated, and so by circulation not life but principles ftital to it were in the end con- veyed to the brain as to every structure of the body." — Wilson on Spasm, &c. If, therefore, such infliction of injury to the brain shall be sufficient to annihilate its functions, and leave no trace of its modus ojyeraudi, what are we to expect from the examination of the nervous organs under other circumstances. In many eases we may ask what do we gain fiom an examination of the blood. Do the circumstances of its possessing more or less serum, forming a more loose or solid coagulura, possessing a buffy coat, fully explain to us all we look for to account for effects. IIow often are we not deceived in our expectations ; and if Ave are not disappointed in appearances, we are doubly so in the effects we had anticipated ; all the symptoms of inflammation shall be manifest, and yet the disease shall not be conquered ; whik-t on the other MALARIA. 231 hand, a bleeding shall prove of the most infinite ser- vice, and the blood shall exhibit nothing abnormal. Dr Itichter relates that a consultation of physicians decided upon bleeding the Empress, consort of Peter the Great, who was supposed to have some internal inflammation, but upon examination of the fluid, to their astonishment it presented the characters of de- bility of the system. It is not upon such tests that we can always hope to find our views confirmed. Why is the blood of a pregnant woman always buflfy ? Why is this appear- ance influenced by the rapidity with which it is made to flow — the size of the orifice — the direction into the centre or sides of the vessel. These disorders are the inheritance chiefly of the opulent, and of such as have no active employments, or who have to live or die upon the smiles of court. These are the circumstances which allow disease to take root, and throw out branches of the most eccentric kind. I have stated in an Essay on Thermal Comfort, that no people are less tormented with cough than the inhabitants of Petersburg during the winter season; but spasmodic obstinate coughs in the spring, which wear the patients out with long paroxysms, and the l)erspiration which the muscular eftbrts cause, are not infrequent. These coughs were formerly mistaken for phthisis, and those wlio went away to die got fiit upon their journey ; but the economy of these coughs, if one may be allowed such an expression, and their resistance to every species of medical treatment, lead me to refer them to the ranks of malaria. They are moot capricious in their attacks, sometimes leavinff 232 MALAEIA. the patient for forty-eight hours, and he congratulates himself upon their departure, when a sudden convul- sive fit, simulating pertussis, convinces him of his great mistake. This will torment him incessantly for a whole day and night, when another respite will in- crease his hopes, or sometimes the cough will seem to subside gradually for some days, and then begin de novo. I have twice been attacked in this way myself, and twice has it endured for three months successively, nor yielded to anything but change of air. In both attacks, however, there was a sudden departure of the cough preceded by local pain. In the first instance, after coughing most violently and being almost exhausted by paroxysm, I ate a plateful of raspberries, and drove out into the country. I had not been absent from home above half an hour when I was seized with violent spasms of the stomach, and was obliged to return. I was bent double almost with the pain. I took, upon going into the house, a basin of hot tea. It Avas scalding hot, and as soon almost as I had swallowed it my spasms ceased, and ^vith them the cough entirely left me. It had lasted three months. On another occasion, after precisely the same history, I was at- tacked by a sudden pain in the coccyx, a^ hicli lasted thirty hours, and consisted of continual shocks, as if from electricity, and so severe as to make me start from my seat. When this subsided, my long har- rassing cough also quitted me. In two other attacks I got well as soon as I k^ft the country. Now^, there is something in this so similar to neuralgic affections proceeding from the influence of malaria, that I must attribute it to this cause. From the nervous state MALARIA. 233 which these coughs produce in delicate females, from the perspiration attending them, from the fever occur- ring of an evening, construed into hectic, and from the Avasting of the body, when these symptoms have been })ut together without being duly analyzed, such cases have been referred to the class of phthisis. As far as I have had opportunities of seeing such, I have generally found that there has been some decided local aifection, either toothache, pain in the cheek, rheumatism of the jaw, or eyebrow ague. These cases get well as soon as the patients leave the Gulf of Finland ; nor are moral effects to be lost sight of in the cure of these diseases, and in throwing light upon their nature. The })romise — the faith in the cure which change of air and scene is to effect Avhen the time of migration arri\cs, arc fulfilled at the time. There are few females in St Petersburg who are not subject to nervous headaches. These are, I think, attri- butable in a great measure to the heat of the rooms and the close air of the apartments, which are useful only as preventatives of phthisis, but are far from conducive to strong health; these affections of the head are accompanied by varieties of uneasy feelings, loss of appetite, sleeplessness, vertigo, and more or less of fever. They are not relieved by country air nor the admission of free air into the houses, nor by the re- moval of the double windows at this season, because with the circumstances that permit of these opera- tions, others arise. The emanations from the decayed vegetable matter which were kept under by a coat of snow and hard frost are now let loose, and it is in the s|)ring season that all these affections are most aggra.- 234 MALARIA. vated. This is the season of the greatest moi'tality ; and the breaking up of the ice, and its departure from the Neva, are most dreaded by those who have long been ilL II s'en ira avec le debacle, is a phrase in the mouths of all the Mrs Qaicklys in St Petersburg. It is the turning of the tide with them. To those, however, who are able to get away, it is the speedy return to pristine health. Those who are robust by nature brave this climate with impunity; those whose lives are active, and employments sufficient to occupy their time, enjoy the best of health ; but, to the ailing and nervous, it is a species of martyrdom. Hypochondriacs abound, and I have known such quit the country for fear of worse consequences in a mental sense, and return again in a fev/ months to laugh at their own folly. Dr Macculloch ascribes this state of ill health, and all these symptoms, to which others might also be added, to that poison of malaria, which generates obscure and chronic remittent. Whether a long resi- dence in St Petersburg would lead most to adopt his theory as to the cause, I know not, but I am sure that he would have been strengthened in his vicAVS, by what he would have himself witnessed. A young lady of very full habit, was suddenly attacked with violent pain in the head, which threat- ened of apoplexy. She lived at some distance from town, and some hours elapsed before I saw her ; when I did arrive, she begged me to bleed her or her head would burst. I found the pulse very full and com- pressed, and I took away sixteen ounces of very dark coloured blood. I was requested to remain the night, and during this, as the symptoms Avere not sufficiently MALARIA. 235 relieved, I took away ten more. In the morning she was better, and I did not see her again till late in the evening, when I was induced again to bleed her, and took away eight ounces. The head affection was from this time relieved, but the following day she complained of burning pain at the epigastrium, which was painful upon pressure, and thirty leeches were applied. The inflammatory symptoms were then conquered, and this is the largest quantity of blood which I ever took from one patient during the time I practised in Russia. A day or two after the application of the leeches, I was sent for in a hurry, and was informed that she was dying. Upon my arrival, I was told that she had had a fit, and the attendants supposed her in extremis. She had rallied before I arrived. I was requested to pass the night and following day there, and about the same hour the next day, she Avas attacked in the same manner. Violent spasms of the limbs, accompanied by a shrill cry — convulsive twitchings of the mouth — the eyes turned up in their sockets. There was no rigor. It was decidedly a form of hysteria. I gave her a very brisk dose of calomel, which brought away much offensive matter. The following day the fit returned much at the same time, but less severe ; the calomel was repeated. She Avas removed to town, and finally recovered, after what the Germans style a long mas- querade des Nerfs. Dr ]Macculloch attributes these hysteric affections to the influence of malaria. The attack occurred in the autumn, in the rainy season, and in a marshy situation ; and though I do not attri- bute the first blow to it, still, it is probable, that the 236 MALARIA. depletion made her suscei^tible of some influence of this natm'e, which remained in hei* system for some months afterwards. Rheumatic fevers, and local affections of the inter- costals, are very prevalent. Where these are treated upon the supposition of pleurisy, they are very much prolonged, and sometimes aggravated. I have known fever of a typhoid type supervene to these depletions. Under all circumstances, they are very tedious, and, in general, perfect recovery is not effected till the season of migration arrives. It must be borne in mind that convalescences in these countries are very protracted. There is a disease of convalescence, if it may be so styled. This arises from the circumstance of in-door confinement and heated rooms. It is too great a risk to expose the patient to the rigours of the atmosphere, upon recovering from illness, and nothing but fresh air will complete the recovery ; so that if a person be subjected to any serious illness in the month of November, he is sure to be a prisoner till the following April. This does not prove merely a passive evil, it becomes active, and generates a nervous state, which harrasses both patient and practitioner ; hence the ffreat migration of convalescents wdiich I have men-, tioned, at the breaking up of the ice in the Gulf of Finland. These cases occur more frequently, and are more obstinate, where much depletion has been used. Large bleedings never answer in these lati- tudes ; the vital powers are too much exhausted by them. Even in inflammatory cases, where they can- not be dispensed with, small, but repeated bleedings, MALARIA. 237 arc more suitable than one large one. From ten to twelve ounces, is as much as should be drawn at a time. From Avhat has already been said upon these nervous complaints, and their origin, it will be evident that little is to be expected from any other source than that wliich shall remove the offending agents, or restore the nerves to their normal functional condition. That this state is much aggravated by indiscriminate quack- ing, and by the constant use of blue pill and black draught, cannot for a moment be questioned. This has ))een fully exposed by Dr Macculloch ; and Dr Hol- land, in his Notes and Observations, has added strength to these opinions. " In many instances," says the former, " the change of place, which leaves the medi- cine chest behind, cures the disease." How far the health of families is preserved, or the rising generation rendered vigorous, in consequence of the maternal medicine chest, or the daily visits of the apothecary, is amply evinced by the fact, that in such families, and in such individuals, and often through a long life, sound health is as unknown as a perpetual state of disease is common I must iierc notice the effects of this practice in producing what are called nervous diseases. " The patient was a single lady of thirty, of a vigorous and healthy family, and, to all appearance, of an originally vigorous constitution, without organic affccti(ms, and who had never known any real disease ])eyond the usual disorders of infancy in their more blender forms. Every nervous affection enumerated in AVhytt's formidable catalogue had been, liowevcr, licr torment almost from childhood and on makinir 238 TREATMENT OF AGUE. inquiry respecting her own practice, which experience has taught me to place among the first, the answer WHS, that she had taken salts or calomel almost every day since she was eight years of age, and was sur- prised that she should still be ill, and not in the least degree better." — Maccidloch, Vol. I. p. 465. TREATMENT OF AGUE. If it w^ere to be asked, What will cure a fit of the ao-ue ? it might be replied to by the question. What will not do it ? It is cm^able by every moral emotion, by every drug that acts upon the imagination. Now, those who have passed through the cold stage of intermittents will not be persuaded that it is no reality. The strongest are unnerved by it, — death is sometimes caused by the shock. " He had a fever when he was in Spain ; And when the fit was on him I did mark How he did shake : 'tis true this god did shake. His coward lips did from their colour fly ; And that same eye, whose bend doth a\ve the world, Did lose its lustre ; — I did hear him groan." Now, this was not a matter of mere imagination to Cfcsar, but he might have been cured of all this by a cobweb, by a live spider taken internally, by an abracadabra tied round his neck ; what similar means have not prevented a fit of ague ? " The simplest remedies," says Dr Macculloch, " are those which act iipon the mind, or through it In whatever way these remedies act, the fact itself is TREATMENT OF AGUE. 239 an important one, as relates to the theory of the dis- ease, since that action and the mode of it, also the suddenness, among other things, go far to prove that it is situated in the nervous system, or in the brain and nerves ; and that to influence that system directly and solely is the cure, and probably the end to be arrived at by every remedy." — Vol. i. p. 434. " In enumerating the difterent remedies which act in this way, either from disgust, or the opposite effect, we must not omit the sight of a beautiful woman as having, from the testimony of African travellers, pro- duced a cure. Fear, the sudden necessity of exertion, hope, joy, unexpected success, or sudden grief and disappointment, enter into the same cateo-ory."— P. 437. " As regards the remedies of a domestic nature, which are given with this intent, and are considered stimulants, under whatever form they are given, alcohol, opium, and spices, represent the whole." It is not, however, of the treatment that we have to speak in this essay, except to prove that it is directed to the nervous system for the cure of a ner- vous disease. If it be objected to this, that none of the so called specifics will cure many cases of ague, it must be remembered that these diseases soon produce other consequences, which demand other treatment. Thus, the use of mercurials is directed to the chylo- poictic viscera, which arc impaired by the shock to the nervous system. It is only in the commencement of the disorder, therefore, that we must look for success in the use of these remedies, when to cure a fit is to terminate the disorder. 240 TREATMENT OF AGUE. The blood and secretions maybe secondarily aflPected, but they are not the prime movers of the disease.* Moreover, mercury has a peculiar action on the ner- vous system. I had some opportunities of becoming acquainted with the iSIoldavian and Wallachian fevers, when I was in Odessa, and found Sir A. Chrichton's obser- vation, that bark alone was seldom sufficient for their cure, perfectly true ; but I found it equally apply to the agues in St Petersburg. Dr Baillie has observed, that where bark fails to cure an inter- mittent, a grain of calomel at bed-time, for a few nights successively, will generally accomplish the object, and with this I generally commenced the treat- ment. The following case occurs to me : — A lady of * Dr Stevens observes, " The mind has an influence over the motion of the blood, and there are many reasons for believing that the nervous, like the electric fluid, can produce a sudden change in the quality of the vifhole circulating current. Excessive grief, violent pain, &c., may derange its physical properties, and this derangement of the blood is probably the immediate cause of the fever which sometimes follows ; for, often where such cases are fatal, no appearance can be found in the solids to enable us to explain the cause of death, while the blood is invariably found to be dark in colour in a fluid state, with little disposition to coagulate either while in the vessels or when exposed to the air." — -P. 260. Now, if all these changes can be immediately effected in the blood by a fit of passion, thx'ough the agency of the nervous fluid, — efi^ects which resemble those from the influence of a specific poison, — why should the latter require so long a time before its operation is manifest? and why should it not, when applied to the brain, produce the same consequences as those effected by moral emotions ? Why should not the shock to the nervous system, which is capable of thus changing the blood, be the cause of the fever, as it in reality i-;, and of which the deterioration of the circulating fluid is an efl'ect ? It is surely quite as romantic to attribute fever to an instantaneous derangement of the nervous fluid from the effects of passion, as to a dose of malarious or other poison to the brain. TREATMENT OF AGUE. 241 middle age, and very full habit, -syitli eruptions on the skin, had been long in an indifferent state of health. I can find no better term for it. She was never laid up ; but she was never well ; headache, toothache, chronic rheumatism and flying pains, loss of appetite, &c., had harrassed her for months. She at length was seized with an ague fit, for which her German attendant immediately prescribed bark. It did her no good. She felt its influence, but it did not relieve her from her painful and nervous condition. An English prac- titioner was requested to see her ; he recommended a dose of calomel, to be repeated two or three times before having again recourse to the bark. His views met with decided opposition : but he was attended to, and the patient was radically cured in ten days. Upon the authority of the late Dr Baillie, I gene- rally prescribed a grain of calomel for several nights before I used the bark, and I was seldom disap- pointed. I have succeeded by this plan when others, by commencing immediately with the specific, had failed. In some instances there was not time for such practice, as in the case of the courier, before alluded to ; the fit would be so severe as to threaten danger on its renewal ; and in such cases I must state what I had an opportunity of doing in the Medico- Chirurgical Society, that a very large dose of quinine was the only way of securing success. I mentioned that I had often failed in the commencement of my prac- tice by giving undcr-doses, and that attributing my failure to the bad quality of the drug, I imported some quinine from England. The failure was the same. 1 then [jrc-cribcd it in ten grain doses at three intcr- 242 TREATMENT OF AGUE. vals during the intermission, and I was much more successful. Dr Gregory confirmed my vievrs by re- lating similar occurrences in this country, and urged the employment of full doses in the commencement. When the snake was thus scotched, it Avas necessary to resort to mercury, in the shape of calomel, in small doses, to complete the cure. The muriate of ammonia was most serviceable in this stage of treatment. The following was the usual fonii : — li Amnion, muriat. 5 j. Ext : Taraxac 5 ss. Aqua? : Petroselin, 5 vji. Cujus sumat jeger cochlear ampl. duo ter de die. This, wdth one grain of calomel at night, for four or five times, and then every other night for as many more, seldom failed in ordinary cases. I must state here, that after some, nay, many trials of the blue pill, I was obliged to abandon its use in that latitude, both in the treatment of visceral affections and in the venereal disease. I know not Avhat may be the cause, and I wish some one more able than myself would take up this subject ; but medicines do not act in the same way in all climates. The blue pill constantly baulked me. I latterly employed calomel, and the bichloride. In the case of intermittents, I have to mention a singular anomaly. It is positively fatal to a medical man's reputation, to prescribe arsenic to the higher classes — they will not hear of it. There is no means of disguising it. I did succeed, for some time, by writing SoliUio Fowleri, to which the eye- TREATMENT OF AGUE. 243 brow ague yields in general sooner, than to any other medicine; but it was discovered, and I could not persevere. It is usual, under all circumstances, for a patient to send to the druggist's for a copy of the prescription in the vulgar tongue, and this is sub- mitted to a council of friends before it is taken. There is no means of escape. Now, it is positive that the people take this poison in very large doses. An old lady, who lived in the country, and whose kindness to the poor was un- bounded, spent a deal of money in the purchase of quinine, by which she cured a great many gardeners, -who, living among the enormous cabbage plantations in the neighbourhood of the city, and often lying down to sleep on decaying vegetable matter, are very subject to agues in the spring, when they come from their villages to work in these plantations. She once told me, that an old Avoman in her neighboiu'liood, cured the ague much better than she could, and robbed her of her practice. I was curious to ascertain the modus medendi, and foimd that she sold bottles of beer for this purpose. The effects were violent vomiting and j^iurging, severe cholics, &c., but the disease was cured. Arsenic was the remedy, and the answer as to the (piantity put into the quart of beer, was as mucli an will He upon a sixpence.* I have no doubt, that some were sacrificed in the experiment, but hundreds were cured by this means. In a paper published in the Lancet, on poisons, I have mentioned the precautions taken by government, to * Tlie coin Orttvcuz is as near the size of sixpence as possiMe, it is worth fivepencc-halfpcnny. 244 LOCAL AFFECTIOXS. prevent abuses, by placing all possible difficulty in procuring deleterious drugs fi'om the druggists shops. It is absolutely true, that a person, who cannot buy a grain in this way, can purchase a hundred weight at the wholesale venders without difficulty, even in St Petersburg. LOCAL AFFECTIONS. A gentleman, with whom I was in the habit of associating daily, suffisrcd from attacks of rheumatism, which invaded him at all seasons of the year and times of the day, and without any warning. In the midst of health, at table, in the drawing-room, he would be seized with sudden twitches in the knee or instep, sometimes on the inner side of the leg, which would soon amount to pain, and, in the course of an hour, render him unable to walk across his room without assistance. The following day he would suffer from constitutional fever, and these attacks generally lasted two or three days ; the pain would gradually leave him, or sometimes instantaneously, as it had com- menced. It would occasiona'ly fly from one leg to the other, but was always confined to the lower extremities. The parts w-ere hot to the touch, seldom discoloured, and never sAvollen. Meteorical changes seemed at times to be the most traceable causes of these attacks. Nothing was of any service either in arresting the seizure at once, diminishing its course, or preventing the usual periods of its return. This state of things had continued for years. He quitted St Petersburg during my residence there, and went LOCAL AFFECTIOXS. 245 to England, whence I learnt that he had no return of his complaints. ^Sciatica is a common affection in Russia, but not more obstinate than in other countries. The most effectual plan of treatment, -svlien taken early, consisted in full doses of colchicum, calomel, and opium at night, and blisters to the part affected. The latter might often be dispensed -with. I have known the tibial nerve the seat of the disease, and causing great pain, particularly at night. This, in one case, was soon cured by calomel and opium. The following plan was adopted for the cure of a very obstinate case of a sciatica, in a young man of my acquaintance, whose complaint had baffled all the ordi- nary means. Needles were pushed deep into the part affected, and heated red hot by a spirit lamp. The cure was permanent after one such species of firing. I do not remember who proposed the operation, nor Avhether it came from the faculty. I can testify that there was no return of the disease for years, and, I believe, never since that period. The brow ague, as I have observed, yields more readily to arsenic than to any other remedy ; but I have found that one application of leeches always ex[)edited the cure. It was only possible to employ the former with English or Germans. The pes anserinus is subject to become affected, and always, as far as I could trace it, from exposure to cold, and to a sudden impression of it. It is not uncommon to see people rub one cheek. It is not very severe, and often yields to opiate liniments. Iritis is a very common disease in St Petersburg, 246 LOCAL AFFECTIONS. and, from its very obstinate nature, I have reason to think that malaria has something to do with it. I have witnessed several cases ; and have observed that those subject to it were rheumatic and gouty subjects. It is also not uncommon for it to fly to the other eye, when one only has been affected for some time. It is a very common sequel of ill treated syphilis. The treatment has appeared to me unsatis- factory ; but in this, as in many other cases, the plan of continually changing remedies without giving any thing time to effect that for which it was first pre- scribed, appears to me the chief error of German practice. Upon none is the maxim of Hippocrates more necessary to be inculcated than on the Germans in this respect, and it is rather an anomaly in their character, for, in most matters, they are a most patient and persevering people. Mercury is not given to affect the system in this disease. A few mercurial purges may be presciibed in the commencement. Leeches are employed ; but in their application the law is to apply them as far as possible from the part affected. Sinapisms to the feet, the brow smeared Avith mercurial ointment very gently, and the hydriodate of potash in ten grain doses, form the basis of the treatment. A rag dipped in laudanum is hung as a curtain before the eye, and this alternated with a bag containing aromatic herbs. The most rigid abstinence is enjoined, and a dark room. I have seldom known the affection subdued in less than six weeks. Relapses are very common ; and, in the cases which I can now call to mind, vision has never been completely restored ; a haze sweeps before the LOCAL AFFECTIONS. 247 eye. The active treatment which is adopted in this country at the commencement, is often deferred till late in the disease, and then makes but little impression. Epidemic opthalmia has frequently made great ravages among the troops. The Knee is subject to malarious affection, of which I have seen several cases. The first which occurred to me was in the commencement of my career in the north; and I am certainly indebted to Dr MaccuUoch's essay for the success of my treatment. A young man of particularly nervous habits, and who had led a gay life, sent for me the day after his wedding. I found him quite lame, unable to walk, suffering considerable pain, and in a general state of tremor. He could hardly speak distinctly. He told me that he was subject to such attacks occasionally, but this was more severe than usual. He was very nervous. There was neither redness nor swelling, but the patella was exquisitely sensitive. I gave him frequent doses of camphor, valerian, and ammonia, and a grain of opiiun at night. The following day he was considerably better, and in the night the attack entirely left him. He died of nervous fever some years afterwards. A much more obstinate case was that of a youug Avoman, who suffered from violent pain in the knee, and who went through the severest treatment for months, Avithout any alleviation. She was subjected to repeated applications of leeches and blisters, and other stimulating applications. Finally, several raoxas were burnt upon the knee, but all to no effect. There was a symptom in her case, which should have led to a different plan from that which was so futilely prac 248 LOCAL AFFECTIONS. tised ; an intermission, viz. of pain for hours daily, the worst paroxysm occurring towards evening. No change in the size of the joint was at any time visible, but it was warmer than usual during the time of pain. I Avas consulted in the case, and recommended quinine, but it was not persevered in, and I could not counte- nance the severe methods of local treatment which were proposed. An old woman persuaded her to tie a string of bottle corks upon the thigh, an hour or two before the wonted paroxysm, promising that it would act as a charm. Faith was placed in her words, and it did so. She missed the paroxysm for several evenings ; as the faith, however, decreased, the pain returned again. Had any thing more of the same kind been adopted, I believe it would have succeeded. This circumstance confirmed me in the idea of the real nature of the disease, and that it belonged to painful neuralgia, from constitutional causes. She migrated in the spring, and since her absence from Russia, has not suffered the slightest inconvenience. I shall add but one more case of neuralgia, which occurred, though not in my own practice. It was one of a young girl of twelve years of age, who suf- fered every evening from lancinating shooting pains in one ear, often so severe as to cause her to cry out and become almost distracted. It resisted various remedies, and finally yielded to mercury. The place of her residence was a i)eaty soil, and the neighbour- hood never free from fevers of the remittent kind ; and it was here that I met with all the worst cases of scarlatina. LOCAL AFFECTIONS. 249 With respect to the use of quinine in all these loc.il affections, as far as my own experience is concerned, I have found it of very little service. Arsenic, where it could be given, has seemed more beneficial ; from calomel and opium, there has often been speedy and positive relief afforded ; but change of air and locality, are the sovereign specifics for these, as for the more general manifestation of constitutional symptoms, from one and the same cause. Now, -what has been said concerning the treatment of constitutional fevers, is equally applicable to local neuralgic affections. The same moral emotions, the same charms, the same quackery, wdiich cure the ague fit, will drive away the toothache. It is the triumph of faith, the influence of belief in both cases. The following case occurred to me early in life, and I believe the first after obtaining the warrant "Universis ct Singulis.*' I had just arrived in London from Edin- burgh, and met with a friend whom I had knowai some years before in the country, where he was employed as an officer of engineers upon the trigonometrical survey. After exchanging a few w^ords, he said to me, Do not you perceive what is the matter wdth me ? I replied in the negative. Wliy, he continued, I can- not open my jaws, and am half-starved. I then found that he could not open his mouth wide, w^ithout caus- ing great pain in the articulation of the jaws. lie informed me that he had been upon the survey in the Shetland Islands, where he had been exposed to all kinds of weather, and had thus got locked jaw. Upon finding that he had been, as he styled it, par-boiled in liot baths, and had taken bark and arsenic without any 250 LOCAL AFFECTIONS. effect ; and, moreover, finding that there was a good deal of pain upon pressure, I told him that I could cure him, and that he should be able to eat a biscuit in a Aveek's time. He shook his head, and doubted much of such a possibility. I begged him to let me try, and told him as the means would be vei*y simple, he need not be afraid. He consented to allow me to put on leeches the same even- ing, and while they were still attached and bleeding, he exclaimed, good God, I can open my jaw^s — before they were all removed, he said the pain was gone, and the movement of the jaw was quite easy to him. He slept better that night than he had done for months, and the following day Avas surprised to find that he could masticate his food without difficulty — there was, however, still some degree of stiftness. I advised a second application of the leeches, to Avhich he readily consejited, and from that time he Avas radically cured. I have stated this case just as it occurred, for I knoAv I shall be pardoned for that selt- confidence, which is the portion of a Tyro, and this was one of a Tyro's lucky hits. It is interesting, hoAvever, as regards the affection itself, and a proof that diseases resembling local neu- ralgia are not to be treated under all circumstances by nervous medicines. I consider this to have been a case of inflammation of the cartilages of the jaw, and not of the nerves. Some years after, the same patient was affected with iritis, from similar exposure to cold. HOMCEOPATHT. 251 PART XL Homoeopathy — Instinct and Reason — Memory. HOMCEOPATHY. Although nervous disorders arise from local circum- stances, and the removal of these sometimes cures the complaint, still they demand medical attention, and are prolific sources of revenue. It is here that the homoeo- pathists have unfolded their banner opportunely, and marched triumphant over the field. It is as easy to prove that hundreds of nervous affec- tions have been allowed to get well under this treat- ment, as it would be diflficult to decide that any diseased organic structure has been thus restored to its normal state. This system is, in the truest sense, the " art of amusing the patient whilst nature cures the disease." I have elsewhere endeavoured to analyze, in some measure, the claims of tliis new species of quackery, and I shall reproduce the arguments here as not out of place in the consideration of a variety of affections, Avhich are proved curable by moral influence. According to the principle laid down by the author of the system, it implies the doctrine, that deranged animal functions are remediable by the application of such agents as would, if administered in the normal 252 IIOMCEOrATHY. state, produce similar dei'angements. This is asserted on the authority of Hahneman, "who, in the observa- tion that fire draws out fire, instances the application of his theory in the practice of Dv Kentish ; and the difference between^homoeoj)athy and allopathy is this, that one goes along Avith the disease, the other wars against it. We shall not enlarge upon the various coincidences which seem, a priori, to justify this statement, but shall state our belief, that a definite combination of atoms is as necessary to produce specific action in the animal as in the chemical laboratory, and that a spe- cific disease is not the result of indefinite combinations, as gases are not formed by indefinite mixtiues of certain ingredients. If we take the combinations of oxygen with nitrogen, we have an opportunity of examining several compounds which differ from each other in colour, in smell, and in external characters, as they do more essentially in the effects which they produce in the animal economy. It may be stated, therefore, that chemical combinations are the result of elective aflfinities, without which election matters do not combine chemically. It is more than probable that such elective principle is active in the formation of specific diseases, for we believe in these and in their appropriate remedies. Organic chemistry seems to confirm these ideas. AVe choose for illustration, that affection, which is parti- cularly brought forward by the homoeopathists to prove that certain agents applied to the body will produce morbid action in a state of health, and that the normal state will be restored by the application of the same HOlICEOrATIIY. ZOO agents, — Ave instance scarlatina. If belladonna berries be swallowed inadvertently, nausea, vomiting, fever, and a scarlet eruption will ensue. Hence belladonna is employed as the natural remedy for the cure of scarlatina. It is used, also, as a prophylactic against its contagious influence. We have known whole nur- series put upon a course of this drug, where a child has been labouring under the disease. This is a comprehensive style of practice, — a kind of medical trinity, recognizing, in the same agent, the power of creating, annihilating, and preventing, a particular malady. But to come to the point. Is a scarlet skin, accompanied by the aforementioned symptoms, suffi- cient to constitute the specific disease, scarlatina ? AVe have seen enough of this disastrous complaint to prevent us from regarding it as merely an eruptive fever of a common kind ; but to induce us to believe that we recognize in its mode of attack, its progress, its fatality, or in its sequela, some specific morbid poison not producible by a dose of belladonna, the effects of wliich are no more comparable to those caused by the real disease than is the redness of the flagellated schoolboy to the efflorescence of the same eruptive malady. Let us trace the progress of the two affections through all their stages before we admit their identity. Docs belladonna produce a scarlet eruption in all individuals to whom it is administered, or does not this effect come under the category of idiosyncracy, as we see it results from eating salmon, shell-fish, mush- I'ooms, &c., in peculiar constitutions? How many deaths are upon record of the disease produced by 254 HOMCEOrATHY. belladonna, Avliere it has not been taken in sufficient quantity to act as a sudden poison ? When its influence has been sufficient only to simu- late scai-latina, Avhat proportion of mortality is there in the simulated and real disease ? Do patients affected by the former sink in the course of forty-eight hours from the outset, often with little suffering, slight fever, scanty eruption, slight derangement of senso- rial powers, but with difficult breathing, livid fauces, difficult deglutition, and with swoUen purple fingers, as they do but too frequently in the latter. Is the desquamation which follows in the one case, M'here the patient survives a slight furfuraceous, peel- ing off the cuticle ? or does the skin come aAvay from the arms and hands like a leather glove ? Is such ever the case in belladonnic disease ? Are ulcerations of the tympanum, exfoliation of the bones, violent inflam- mation of the eyes, morbid secretions from the lach- rymal passages, swelhngs, abscesses of the v.'hole chain of glands in the neck, dropsical efiusions into the cavities, hydrocephalus, are these ever the sequela of irritation from belladonna ? Is the affection produced by it communicable by contagion ? If these symptoms have never coincided in the pro- gress of the two diseases, there are no grounds upon which to establish their identity. If they are not the same diseases they are not produced by the same causes, nor are the remedial agents the same. Genuine scarlatina can no more be produced by a combination of belladonna with the animal secretions, than a specific gas can be formed by the mechanical mixture of un- combinable elements. nOMCEOPAXnY. 20D It is again stated that mercury will produce all the symptoms of the venereal disease, hence the true homoeopathic rationale of administering it for the cure of syphilis. That it does cure tliis complaint is beyond doubt ; but no justification of its use is to be founded upon the bare circumstance of its causing an eruption which simulates those of secondary symptoms ; for as twenty grey horses will never make a white one, so a variety of merely similar symptoms does not consti- tute identity of disease. If, then, the diseases be not the same, the argument falls to the ground, — the prin- ciple fails upon which the whole scheme is based, and there is no medical signification in the term Homa-o- pathy. Take another view of the subject. Supposing that the remedy which we apply for the cure of a malady should be capable of producing the same, if adminis- tered in the normal state, what principle warrants the conclusion, that by adding fuel to fire we can control a furnace ? If a disease be characterized by a variety of dis- tressing symptoms, is there any philosophy in adding to their number or intensity by the employment of similarly exciting agents ? Can we subject life to the laws of inorganic matter, and, upon the principle that similarly electrified bodies repel each other, generate a positive morbid electricity, in the hope, that when the already positively electrified morbi^l pole shall be brought in contact with the similarly electrified arti- ficial end, the two will fly off from each other? AYe might, upon such principles, recognize the unity of disease, — " the chronothermal principle, the electric 256 HOMGEOrATIIY. state of the brain, and class love and pregnancy among the varieties of intermittent fever." The term Homoeopathy is lost sight of in the prac- tice of the system, just as the name of Butler is lost in his hero Hudibras. In its general acceptation, the public only recognizes the infinitesimal dose system, ■which, with that same public, constitutes the great charm of homoeopathy. It is rightly conceived by those who hold their burnt children's fingers to the fire, and keep them there as long as the increase of pain can be tolerated by the sufferers. The principle is directly opposed to tlie ancient belief, " chaque mal est gueri par maladie contraire" the idea upon which the old King Charles acted when he invoked the aid of Joan of Arc to remedy the dis- asters accruing to the state from his amours with Agnes Sorel. We do not deny that advantages are to be derived from infinitesimal doses of medicine. Much mischief has been generated by long and protracted drugging wuth powerful remedies in chronic disorders, many of which would have been benefited by rare interfer- ence, or, which comes to the same thing, by homoeo- pathic treatment. " It can do no harm." This is its rock of salva-- tion. This sweUs the ranks of Ilahneman ; but if such nonentities be negative for harm, can they be positive for good ? Is the drowning man, Avhom physical exhaustion incapacitates for saving himself, more in- indebted to the one bystander who Avill not lend him a helping hand than to the other who makes HOMCEOPATHT. 257 o-reat efforts to save him, altliougli he may foil in tlie attempt. But in reahty this practice does effect positive good, inasmuch as by that part of it which inculcates abstin- ence, regularity of diet, sober hours, the avoiding of all physical and moral excitement, great assistance is afforded to the vis medicatrix natura;; — add to which the faith in the remedy which works such Avonders over all disorders likely to be influenced by it, viz. the nervous. It is only ascribable to the perverseness of our natures that Ave implicitly conform to particular re- gulations, when they are associated with something new, although we should never comply with them if prescribed under other circumstances. Would patients but do one half for an ordinary practitioner that they do for an honifcopathic one, they would soon be able to dispense with both. In all cases of a nervous and chronic character, where little is to be gained from medicine, and much from moral treatment from the removal of existing causes, from the stimulus of novelty, and from faith in nonentities, this system is invaluable. I had one fair opportunity of testing homoeopathy. General slipped in the winter season and bruised his shoulder; he thought it was dislocated, and sent for me to examine it. I found that there was no luxation, but very severe contusion. I ordered thirty leeches and fomentations. The following day the tumefaction had much subsided, but he still com- j)lained of a good deal of pain. He said to me half in joke, how long Avill it take to cure this by the ordinary mode of treatment. It is not so easy to say I replied. 258 HOMCEOrATIIY. You Avill long feel the effects of such a blow, and pro- bably you will not use your arm freely for a week or two. He paused, and then said, my lady is at present under the care of an homceopathic doctor, and she is very anxious that I should let him treat me ; have you any objection to meet him here to-moiTow. I replied that I should have the greatest pleasure in doing so, as I was anxious to test the practice, and this was a good opportunity. (I must observe that he had him- self great faith in it, but did not think it good for a bruise.) The following day we met, and my colleague examined the arm and was fully acquainted with what had been done, nor at the time did he make any the slightest objection to my practice. I informed him of the conversation which I had had with the General, and of my statement, as to the probable time required for the cure in the ordinary plan of treatment. I told him I was willing to put the case entirely into his hand if he could promise greater expedition. Yes, he assured me, " Uber-morgen," the day after to-morrow, all wdll be right. He applied a lotion of arnica, and gave a powder of arnica at night. I saw the patient the fol- lowing day ; the ann was no better, but he had passed a good night. Upon meeting the doctor the day after, and finding things no better, I reminded him of his promised cure. He shook his head and said, " Had you not applied the leeches it would have been the case." But you did not say so at first, I replied, although you Avere aware they had been applied. He continued his treatment for some days, when I was again applied to, as the plan had failed, — the pain and weakness yielded to the ordinary means. HOMCEOPAxnv. 259 Even in this case I think the operation of the nervous influence is to be traced. The powder pro- duced the rest at night, because the faith was sufficient in the commencement to quiet the nerves ; but this charm vanished as soon as the homoeopathist pro- nounced that the previous treatment had interfered with tlie results to be expected from his plan. In the apology wdiich we offer for the influence of the nervous system, we find that this homoeopathic quackery holds an important place. AVe shall not pursue the subject farther at present, as enough, we think, has been brought forward to rescue the nervous system from the submersion which threatens it by the revival of the humoral pathology. These doctrines are again reviving, and there is, doubt- less, much in them worthy of consideration ; but it is the misfortune under Avhich all systems labour, that their advocates, carried away by intoxicating potions of adulterated liquors, find the flavour of the genuine jui^te milieu too mawkish for their tastes. In such paragraphs as the following, we cannot recognize the spu'it of calm research which should guide us in the pursuit of inquiries where the broad path leads to a precipice, and the narrow path is so entangled with intricate vmderwood, as utterly to impede our progress. Those beautiful prairies of the far west, whose carpets are bedecked with the richest flowers, which ask for the hand to gather them, whose forests dotted .'iI)out like islands in the sea, arc not encumbered by tliorn or briar, but allow of ready and iminterrupted transit throughout, without entangling the traveller's 260 noMCEorAxnY. foot by a single snare, — these are not the regions of tlie physiologist. It is a mazy path which he has to tread, with but little light to guide hira, and that little often proving an ignis fatuus. " Self-moving, self-producing, maintaining its own fluidity, arresting its own current by self-coagulation, the blood, in its wide range of capacity, is affected directly and at once by the countless agents of vital impression " The blood entire is sensitive as the individual nerve of external impression, instantaneously and simultaneously perceived through all its distributions." We cannot subscribe to such opinions ; and those, perhaps, who do, may with equal justice object to such as those with which we terminate these observa- tions, as too exclusive on the side of the question which we have embraced. In the language of the late Dr Macculloch, than whom few ranked higher among scientific men, " Nor can physiology and physic well forget their offices, — forget that it is not the circulating system, that system which has almost drawn all favour to itself even in their minds, but the nervous system which is the prime mover : the cause even of all circulation, of all motion, of life itself; that it is the life ; that the nerves are the man — the animal ; and that every thing else, the whole animal structure, in all its parts, is a mere machine and a chemical laboratory, as purely subservient to the nervous system as is a steam-engine to the intelligence of man. Without a nervous system there is no animal, — there can be none ; without a circulating one there are myriads." IXSTIXCT AND KEASOX. 2G1 INSTINCT AND REASON * Much has been said, and great are the pains which have been taken, to draw the line between Instinct and Eeason, and the whole seems to resolve itself into the conclusion, that what is denominated instinct in the brute is dignified by the title of reason in the man, and vice versa. If the latter were a simple fsiculty, such misrht hold good, but if it be considered as a compound one, then the totality of all the component parts is alone the privilege of the human species. The one, as much as the other, is dependant upon organization. Instinct is not the same at all periods of animal life any more than reason. It is matured with the development of the organs. Young animals are said to be foolish, as are young children. What meaning is attached to the saying, that old birds are not to be caught with chaff? It can only imply that tlicy know better, and this includes mental educa- tion. ]Many of the reasoning faculties are compre- liended in tliis species of knowledge. Dr Bostock, in his Elements of Physiology, has allowed that instinct has the preponderance over reason in animals, and that the instinctive faculties are weak in the human subject ; but he does not deny rational faculties to brutes. It will entirely depend upon the meaning we attach to the word reason, in order to prove in what the difference consists between it and instinct. Many of the wonderful feats related of animal sagacity are, I think, referable to instinct * Sec p. 10, Part I. 262 INSTINCT AND REASON. only. On the other hand, it is not true that this said faculty, whatever it may be, is the attribute of any exclusive species. It is the property of the whole race. All animals are capable of education, — all are not equally so, — all do not possess the same quantity of natural talent. It has been said by some, that education can only be carried to a certain extent Avith the lower order of animals, e. y., that after teaching the elephant a certain number of tricks, his education is finished, — he can go no farther. I very much^doubt this assertion ; he goes as far as his keeper wishes for the purposes of his hire. Animals are said to have no idea of the uses of fire, nor how to supply it. Thus, a monkey sitting in the corner of the chimney, with logs of wood around him, will let the fire go out and shiver with cold, and yet never put a bit vipon the embers ; still I have known a dog to open the door of the stove Avith his foot when he found it shut, and this he did regularly when he came into the parlour previous to lying downbefore the stove. Again, it is argued, that in the construction of the honey cell, it is an instinctive faculty which has led the bee to economize space : this is certainly true, but it is not proved that the insect can make no other arrangement. On the contrary, if the work be pai-- tially destroyed, the bee will restore it as it was before ; but if, in consequence of continual depredation upon parts of it, it is easier to complete it upon another plan, it will abandon the original instinctive model and change the style of architecture. It is difficult to suppose that animals can dream upon mere instinctive powers, and yet, as we have instanced in the chapter INSTINCT AND REASON. 263 on dreams, there is no doubt of the fact. Memory is one of their attributes whether sleeping or waking. The effects of liquors upon the animal senses are the same as upon the human, though it is only the pig which seems to take pleasure in tliis species of recrea- tion. The passions are all in full force among them, — love, hatred, revenge, jealousy, are of daily obser- vance. I once saw the effects of the latter upori a quail, that literally died of chagrin. A young lady had a pet quail that lived in her room, and which she fed and caressed. A squirrel was introduced, and on the young lady paying more attention to this new guest than to her old favourite, the bird ran about the room distracted, whining and crying, would not touch food, and died on the second day. How far animals are capable of laying down plans for the execution of their purposes, when revenge is their object, the anecdote related of the monkey in the Penny ^Magazine affords an astonishing proof. " A monkey tied to a stake Avas robbed by the Johnny Crows (in the West Indies) of his food, and he conceived the folloAving plan of punishing the thieves. He feigned death, and laid perfectly motion- less on the ground, near to his stake. The birds approached by degrees, and got near enough to steal his food, which he allowed them to do. This he re- peated several times, till they became so bold as to come within the rcacli of liis claws, lie calculated his distancx', and laid hold of one of them. Death was not his plan of punishment. He was more refined in his cruelty. He plucked every feather out of the bird, and then let him go and show himself to his compa- 264 iNSTEsrcT and reason. nions. He made a man of him, according to the ancient definition of a " biped Avithout feathers." It is difficult to say, therefore, in -what the differ- ence consists, if we look to the two only in the sense of powers resulting from organization ; and that these two powers, or these modifications of the same power, depend upon it, cannot be doubted ; for they grow with the growth, and strengthen with the strength of the latter, and are impaired or annihilated in the physical injuries which it sustains. The diflference is only in degree, but this is so great as almost to constitute two distinct powers. If the dog be capaljle of availing himself of the comforts of a stove fire, he will never, by any stretch of his mental powers, be able to invent a safety lamp. If, however, the higher powers of reason be denied to animals they are not, on the other hand, charge- able with some of its less noble attributes. It is doubtful w^hether they possess that species of sophistry which allows man, under certain circum- stances of self-deception, to make evil appear good, — and of necessity a virtue. If a dog Avere caught by the leg in a trap or gin, would he find such means of consoling himself as Hudibras did when his feet were fast in the stocks ? It was then, and not till then, perhaps, that the knight understood the value of his spiritual half — the uncon- finable part — the free agent : — " Quoth he, — Th' one half of man, his mind. Is sui juris uneonfineil. And cannot be laid by the heels, Whatever the other moiety feels." INSTINCT AND REASON. 265 It was by dwelling upon the advantages of one that he lost all feeling of the other, as others have done before him. Plere then, as he himself expresses it, the rationalia have advantages over the animalia, and pur- suing his system still farther, sophistry allowed him to believe that his valour was increased by his defeat. The rational faculties of Ralplio were of a much less noble order, and mark the difference between the man and the philosopher. His mode of reasoning ap- jiroaches, or rather hardly soars above, that which the dog woidd have manifested under similar circum- stances : — " Quoth Ralph, — How great I do not know, We may by being beaten [iroic. But none that see, how here we sit, AVill judge us overgrown with wit." The sophistry of Hudibras allowed him to glory in his captivity, — his mind soared as his body became debased. Ealpho's inferior soul was downcast and mortified, — he regretted the want of that Avit or cun- ning which (had he possessed it) might have preserved him from his disgraceful imprisonment. The dog might feel as much in a similar case. We say of animals that they go mad, — that they lose their senses. We say the same of our species, but we say also that they go out of their minds. This is not said of animals. There seems to be some difference between the two, if we may judge from what language implies. We never say that a man goes out of his soul, — to lose one's soul has a totally different signification. Soul implies, therefore, more than mind or senses ; N 2Q(^ MEMORY. and is not the union of mind, sense, and soul, the power which constitutes human reason ? MEMORY* It was in the gardens of the Tuileries that I met with an old college friend. He was promenading a young lady, who seemed to me to have some difficulty in making herself understood, and still more in under- standing her cavalier. They soon parted company, and my old acquaintance came up to me, and com- plained of the difficulties he found in speaking the French language. " I always had a bad memory, you know, but I can remember facts better than words." I should have instantly recognised my man by this expression alone. He went by the name of " The jMan of Facts" when he was at college ; and it was to this alone that he ascribed all superiority. To possess more facts than one's neighbour was to have the greatest advantage over him. When asked how he got through his examination, he replied, "well enough ;" but regretted that he had not so many facts as the professors who examined him ; and he sighed for his want of memory. Now, nothing can be more erroneous than his ideas upon the subject. A man may possess an im- mense number of facts, and yet be a very great goose. There are two kinds of memory, — the one purely mechanical, which those possess who retain names, dates, and some facts, — the other is the result of an '' From Fraser's Magazine. MEMORY. 267 impression made upon the feelings ; and the complaint of want of memory is in general nothing more than the obtuseness of an important portion of the intellectual faculties. Few clever men complain of want of me- mory, or find difficulty in retaining those things which form a part or parcel of their intellectual enjoyments. The lover of poetry may not be able to recollect when the battle was precisely fought, but if he have ever read Campbell's " Hohenlinden," he can never forget it. He may have read it but once, may not be able to repeat a line of it, but there it is indelibly impressed upon his feelings, — he can call it up when he pleases. It is as much his own as the author's. The man with- out memory or without susceptibility of impression, Avhich is almost synonymous, may have read it many times, and yet know nothing about it ; his eyes have passed over it, but it has not passed through those portals to be indeUbly stamped upon the sensorium. His ear may, perhaps, again recognise the sound of the words, but still the thing itself has escaped his memory, and from the best of all reasons — that it was never there. The want of memory, of which such complain, may be compared to FalstaflPs deafness, " Kather out, please you. It is the disease of not listening, the malady of not marking, that I am troubled Avithal." He who has summed up every thing, and placed all things in their true light, has not been wanting in the true definition of memory. When the Ghost says to Hamlet, " Remember me," he replies, " Yes, as long as memory holds a place in this distracted globe." Here is precisely what we contend for, viz. that 2G8 MEMORT. true memory is made up of impression. Such is implied in the tone of Hamlet's reply, that it would be impossible to forget it, that nothing less than the dissolution of the moral and physical world could prevent him from remembering the scene which he had just witnessed. It became hereafter no matter of will with him to do so. To tell him to forget it or to remember it, would be synonymous. It formed from that time a portion of his moral existence, in- separable but by general dissolution. It is precisely the same in other matters; that which has made a very strong impression is never forgotten ; it may not always be at hand, but it is still there : circumstances may again call it forth, fresh as it was deposited in the storehouse of the mind. The man without memory is the man whose mind is not organized to receive such impressions as excite those sensations which guarantee durability ; such as read the book and lay it down, and forget where they left off; a state which may occur to all at times, when the mind may be preoccupied, but which is habitual with those who complain of bad memories. In these arguments a healthy state of body and mind is presupposed ; for by nothing is the faculty of memory so impaired as by physical derangements. It may be annihilated by organic affections, or it may be suspended, or go to .sleep. It may happen that the power of speech and the use of language be annulled, that all moral existence may seem extinguished, whilst the physical powers continue their functions ; but when the causes operat- ino- these effects shall have been removed, then shall blessed memoiw return with all its force to the point MEMORl^ . 269 where its functions had been suspended. The fol- h)wlng case, quoted from the lectures of the late Sir Astley Cooper, illustrates this position in a most satisfactory manner : — A sailor falling from the yard- arm was taken up insensible, and carried into the hospital in Gibraltar, where he remained in the same state for many months ; he was conveyed from thence to England, and admitted into St Thomas's Hospital. " He lay upon his back with very few signs of life, breathing, his pulse beating, some motion in his fingers, but, in all other respects, apparently deprived of all powers of mind, volition, or sensation. Upon the examination of his head, a depression was discovered, and he was ti'epauned at a period of thirteen months and a few days after the accident. The man sat up in his bed four hours after the operation, and, upon being asked if he felt pain, immediately put his hand to his head. In four days from this time he was able to get out of bed and converse, and in a few more days he was able to say where he came from, and remembered meeting with the accident; but from that time up to the period when the operation was performed [i. e. for a period of thirteen months and and upwards), his mind remained in a perfect state of oblivion," Nothing was remembered which occurred between the periods of the infliction of tlie wound which caused the pressure, and the removal of the piece of bone which produced it, because nothing during that long time liad made any impression on the sensorium. There was a distinct separation of animal (rum moral existence. 270 MEMORY. Mr Herbert Mayo has published a case of double consciousness with temporary loss of memory. It is rather complicated in a metaphysical point of view, but proves satisfactorily the power of impression. There was no loss of memory where the former had had its due influence. Some physical impediment in the circulation operated to prevent its manifestation at will ; but it was there, and as soon as the obstruc- tion was removed, memory again triumphed. I believe, therefore, that we are not far from wrong in accvising our friend of that w^ant of perception, and of impression, w^hich so much limited the number of his facts, that he retained but very few; and his complaint against his memory was unjust and ill- founded, inasmuch as the food w^ith which it is nou- rished must be duly digested and assimilated, before it form an integral part of that intellectual state, which seldom complains of want of memory. PECULIARITIES OF GERMAN PRACTICE. 271 PART XII. GERMAN THERAPEUTICS. SOME PECULIARITIES OF GERMAN PRACTICE. German Therapeutics hold a middle rank of action between the French and the English, being more energetic than the former, and less so than the latter. The Germans boast of a simplicity of prescription, and have a horror of contrarieties, carrying this to a ludicrous nicety, and an unmeaning orthodoxy. Thus, a solution of sulphate of magnesia in an infusion of roses, or the combination of a laxative with an astrin- gent, meets with the severest criticism from those, who profess as much abhorrence of a contreHens in prescription, as nature does of a vacuum. There is much to commend in simplicity of prescription ; and the nudtifarious ingredients which formerly entered into the British recipe, have not undeservedly merited the stigma of farrago, applied to the latter by conti- nental practitioners. Dr Paris long since pointed out the error, and has done much to rectify it. The study of pharmaceutic chemistry, and the supe- rior education of the genei'al practitioner of modern days, have almost accomplished this desideratum ; still, we do meet with combinations of materials, which would be better for a little sifting. To Dr Pereira we 272 SOME PECULIAEITIES OF are indebted for the most valuable information upon these matters ; and the labour he has bestowed upon this subject, has been fully appreciated by the highest authorities at home and abroad. The Germans find the advantage, and it is one of some importance, of administering many remedies per se, which if diffused in mixtures rendered palatable by syrups, undergo decomposition. Thus, chlorine water, which is a very favourite remedy with them, is decomposed by sugar. Colchicum, cherry laurel Avater, tincture of digi- talis, are generally prescribed in form of drops, to be taken in water. The pure and simple influence of such remedies upon the system, and their impression upon disease, are best recognized in this shape. An exception to this is found in their forms of de- coctions, which are the essence of a large proportion of the vegetable kingdom ; and in the influence of minute doses, they countenance the practice of the homoeopathists. Their ideas, well or ill founded as they may be, of infinitesimal doses, are illustrated in the preparation of a decoction much esteemed for the cure of eruptions which disfigure female beauty. It is composed of sarsaparilla, dulcamara, pine tops, beet root, buds of the bii'ch and broom, &c., but the most active ingredient is a small piece of the glass of antimony, tied up in a muslin bag, and boiled for a limited time in the decoction which is supposed to be impregnated by it, although it may have lost no weight in the operation. A German prescription seldom boasts otherwise of more than two or three ingredients. Nothing is held inert, if it be stronger than distilled water ; and if GERMAN PRACTICE. 273 active remedies be administered in a variety of other menstrua, the latter are not chosen indifferently, but with a specific view, and to perform a part in the operation of the whole. One carminative water can- not be substituted for another, it being granted that each has a specific action on- the system. I have known a practitioner cavil at the use of black currant jelly, in the sore throat of scarlatina. In respect to dietetics, their views are peculiar upon some points. In the treatment of fevers, any thing from the animal kingdom is strictly prohibited ; not a drop of milk is allowed, — not even a few drops sufficient to discolour the tea, and this prejudice I have found to prevail throughout the Russian empire with all classes of people. It is considered a matter of the greatest importance. Gruel is the universal form of food alone permitted in febrile complaints, and this in small quantity. Sago is a stepping-stone to more nutritous diet. Tea, with lemon juice instead of milk, and toast and water, made l)v pouring boiling water upon toasted bread, and nut by plunging a bit of burnt bread into cold water, as we manufacture it. They lay great stress upon articles of diet, during the treatment of diseases of all kinds ; and when it is a question of undergoing a course of mineral waters, tables are constructed and suspended in all the eating rooms of the hotels, specifying what provisions are permitted to be used. Salad is so strictly prohibited, that it is not permitted to be served at the tables of the healthy, during what is styled the season in Carlsbad. It is sonic fifty years siuce an English ])ra(;titi(»iK'r 274 SOME PECULIARITIES OF laid the foundation of a reputation, afterwards Avell sustained, by deciding upon changing the modus me- dendi, in a case of fever in a patient of high rank. He insisted upon bleeding, contrary to the opinion of a host of practitioners, all of Avhom, in those days, were imbued with the doctrines of John Brown, so that the Brunonian practice was the law of the land at the period alluded to. It was the late Sir James Leighton, who first ventured upon this innovation ; and from the circumstance of the rank of the patient, of the times as regarded the estimation in w hich medicine was held, &c., he gave the coup de grace to the treat- ment of febrile diseases, as it had been conducted for many years in the North of Europe. How long a period was employed in fully working this change, I am not enabled to say, but certainly nothing can have been more complete than the over- throw of the system, if I may judge from what is now the current practice in public andprivate, of the pre- sent school of medicine. The treatment of fevers is antiphlogistic in the strictest sense of the term ; and, perhaps, convales- cences are longer than they would otherwise be, if the depleting system were not carried to such great lengths as it often is. There is nothing Avorthy of peculiar note in the nature of the remedies administered ; the patients are purged freely with neutral salts, in a mixture of senna tea, a potion well known under the name of the Vienna laxative. The common saline mixture with antimony, is given very freely; and if the animal temperature is very much increased, the nitrate GERMAN PRACTICE. 275 of soda is generally preferred to the nitrate of potash, as possessing more antiphlogistic virtues. It is cus- toraaiy to keep the head cool, with evaporating lotions, and if there be much congestion and fulness of the vessels, leeches are generally applied. In the applica- tion of these, it is always the object to apply them, as far as possible, from the part affected, upon the prin- ciple that, by unloading these vessels, there is a greater influx of blood into them than before. Thus, I have seen in cases of severe headache in febi-ile affections, a large application of leeches made to the loins. In inflammations of the eyes, they are applied behind the ears or the back of the neck, but the favourite treatment is to bleed from the foot. The same holds ffood with blisters, which are not favourite remedies, and sinapisms are for the most part pre- ferred. These are applied in succession upon the ancles, calves of the legs, inner part of the thighs, and on the arms, and between the shoulders. They are not allowed to remain longer than to produce a pun- gent sensation of heat. Vesication is not desirable. The lancet is seldom used in simple cases of fever, where there is not decided determination of blood to any organ, producing pain and uneasiness. Cupping is of rare employment, and those who do perform it, are so little cm fait at it, that I have never seen it performed in a dexterous manner. The Germans adhere to critical days, and often use a bath upon the eve of an expected crisis. In so doing, cold water is poured over the head, whilst the body enjoys an elevated temperature. From what little I have seen of its application, I cannot speak 276 SOME PECULIARITIES OF very favourably of the bath in fevers, when they are fully formed. The patient is generally exhausted by the operation, without any compensating benefit. When nervous symptoms manifest themselves, then valerian and small doses of camphor form the basis of the treatment. Bark is never given as an anti-spas- modic or a tonic, unless the disease assume an inter- mittent tendency. If subsultus tendinum and other indications of nervous debility appear, musk is ad- ministered, and old Rhine wines in moderate quantity. I should, upon the whole, say, that the practice under such circumstances is not so bold, and active treat- ment is delayed to a longer period than it would be by English practitioners. The following case will, perhaps, in some measure illustrate this. An admiral high in the service, was attacked with simple fever and pleuritic symptoms, which in a few days assumed a nervous character, but not of an alarming nature. The patient had been an invalid for years, and subject to all kinds of nervous affections, for Avhich he had taken very strong reme- dies, and had often, from circumstances of situation, been obliged to prescribe for himself. He had been in the habit of taking musk and ammonia in very large doses — of the former to the amount of tho'ty grains. He ate food very highly seasoned with cayenne. pepper, &c., drank strong wines and bottled porter. Such were his usual habits, and without such aid he was always in a state of depression. His mind was actively employed in abstruse studies, and having been, early in life, subject to fits, abstemious living was subversive of his moral and physical power. geema:^ practice. 277 He had been ill about ten days when I first saw him, and had been treated very judiciously by a German practitioner, but he was low and nervous, and wished to see one of his countrymen. His pulse was frequent but feeble, his skin hot and tongue loaded, he had not slept for several nights, and as there was some very slight twitching about the angles of the mouth, it was proposed to give him an infusion of arnica ; he had been well purged previously, and had been taking saline medicines, but without producing any sensible effect. I saw him towards the evening, and from what I knew of his former mode of life, resolved upon chang- ing the plan. I proposed tliat he should take a large tumbler of bottled porter at bed time. This was strongly objected to by his attendant, who washed his hands of all responsibility. I took it upon myself, and gave him the delicious draught, as he styled it, with my own hands. Tlie following day I met my colleague on my Avay to the patient's house, who addressed me, with that good nature and good feeling, which during four- teen years, I ever experienced from the faculty of St Petersburg. La maniere anglaise a triuempho. The patient, soon after taking the porter, slept for eight hours successively, and awoke in a state almost of con- valescence. The porter was continued, and bark and wine were prescribed subsequently, and in a day or two nutri- tious food completed the cvu'e. The Germans adhere to their Rhine wines for medi- cinal use, and seldom use port or sherry. It did not require, perhaps, so sudden a change in the plan of 278 SOME PECULIARITIES OF treatment as is here detailed, nor would the case, under any circumstances, have done badly, but it is probable that convalescence was thus much expe- dited under the peculiar circumstances in which this person had been placed by his former habits of life. Of the cold effusion in fevers I have had few oppor- tunities of seeing it employed in foreign practice. I have known it used in scarlatina, but not at that point when the least good could be expected from its em- ployment, — or rather, when it could only do harm. Of this disease I can only speak in terms of horror, as I have witnessed its fatal issue in this country ; and as I have alluded to it in the chapter on homoeopathy, I can only say that no one plan of practice has seemed to me to be preferable to another. Whenever several members of a family have been attacked, some have always sunk so rapidly that no means could avail to make an impression on the complaint. I should say, that in those cases which are stamped at first with symptoms of decreased vital energy, the system of stimulus, — the use of the warm bath, wine and ammonia, would offer the best chances of a happy issue ; and that this plan is generally deferred too long, — that a few hours may decide upon the life of the patient ; and that in cases where this disease attacks a family, the visits of the medical man can hardly be too frequent. I may state here that I have had the disease three times myself. Once in infancy, and twice I have gained it fi'om attendance on patients. The only peculiarity in the German practice is the use of belladonna, which they invariably prescribe upon GERMAN PRACTICE. 279 the homoeopathic principle, which I have endeavoured to prove to be a false one. Severe and fatal as this disease is in the north of Russia, equally mild and insignificant in their conse- quences do the measles show themselves. I cannot call to mind a single fatal case, not merely in my own practice, but in that of any of my colleagues, during my residence in the Eussian capital. It announces Itself with very severe catarrhal symptoms, but the appearance of the eruption is generally the termina- tion of the complaint. In the treatment of fevers I have merely sketched the ordinary routine of practice, but I must add, that after Dr Stevens' visit, and his explanation of his views upon this subject, the saline practice was adopted by one of my countrymen, and that upon a very extensive scale, as he had an hospital at his command. He employed the oxymuriate of potash, the carbonate of soda, and the muriate of soda, in the same proportions as recommended by the author, and he seemed much -atisfied Avith the effects which followed this new svstem. He told me that he found the tongue set cleaner under this treatment, and the disease upon the whole assumed a milder form than under the more usual method; but where the nervous system manifested much depression, it was not by any means more useful than the old plan, and that more powerful medicines were substituted. The fact is, that in wliatever manner <imple fevers arc treated, they will, if not too much interfered with, go away of themsehcs with but very little assistance. The saline practice was also adopted in some of tlic larger hospitals, but was not found to 280 SOME PECULIARITIES OF possess any advantage over the more established method ; nor were the cooling treatment, and the use of acid potations, so grateful to the fever patient, re- cognised to be so deleterious as Dr Stevens has ima- gined. Dr Holland, in his chapter entitled, " On Points where a Patient may Judge for Himself," has advanced this opinion. In the majority of instances of actual illness, provided the real feelings of the patient can be ascertained, his desires, as to food and di'ink, may safely be complied with There may seem some exception to be made for those cases where urgent thirst gives the wish for liquids of a kind hurt- ful to the stomach ; but it is the fluid alone which is the object of desire ; and when the choice is before the patient at the moment, he will usually take that which most simply satisfies this natural want. — P. 78. Notes and Reflections. If a thirsty feverish patient be asked what is the most grateful to him — an alkaline or acid potation — he will be hardly found to decide for the latter ; and seeing, as I have done, and as it is in general a prevalent practice, that cream of tartar water and lemonade form the usual drinks of patients in fever wards, there can be nothing so detrimental in their use, if we may judge from the results as regards the numbers who make a triumphant exit. In northern latitudes, the people believe that the cranberry is sup- plied them by a bountiful Providence, as a corrective to scurvy and disorders of a putrescent nature ; and the feverish peasant has often no other means of assistance than what this berry, soaked in water, affords him. Apples sliced, and allowed to remain some hours in water, impregnate it with a subacid flavour, and this GEEMAN PEACTICE. 281 is a common fever drink for hospital patients. It would be in such cases probably, as Dr Holland has maintained, that the patient might fairly be allowed to judge for himself of the quality, whereas the dis- cretion as to quantity must be left with the physician. Grape Cure. Those who have practised long in Russia will have been made conversant with the cure du raisin. I had an opportunity of becoming so when in the south of the empire, and in a grape country. It is necessary to state in what this cure consists, and for what class of diseases it is recommended. The latter may be dis- missed at once, by stating that all those functional nervous affections, which resist the routine of treat- ment generally employed, are the cases which may be so benefited, seeing that the discipline is more into- lerable than the disorders for which it is instituted. A lady of rank leaves her bed of down and cushioned canopy, and migrates into the country, — turns a poor family out of their habitation (not without making them an ample recompense) and becomes the tenant of a filthy hut. This is part of the cure, viz. to forego all luxury, to sleep in the peasant's crib, to sit upon his bench, and to avoid anything in the shape of com- fort. The grape alone for meat — the grape for drink; a small quantity of dry bread is perhaps allowed. This is continued for the space of three weeks, and it is no wonder, if all circumstances are taken into con- fjidcration, that a cure is effected. I have known 282 SOME TECULIARITIES OF people of the highest rank subject themselves to such discipline, and have full faith in its results. It is homoeopathy and hydropathy in another shape, and as the Italians say of all the varieties of form in which they make their pastes, c'est toujours du macaroni. As to the physical effects of the grape, which, when the only food consumed, may be supposed to be taken in very large quantities, they are laxative to a con- siderable deofree in the commencement, so that the treatment is not altog-ether neo-ative. I must here protest against the statements of itinerant temperance society lecturers whom I have met v/ith in England, and who have persuaded their audiences that wine is not sanctioned upon scripture authority as a potion for man. They strenuously insist upon it, that the juice of the grape is the only thing alluded to. It is easy to defeat them upon this ground, for the word wine is not one of doubtful or equivocal interpretation. It means fermented liquor. As such, St Paul recom- mended it to Timothy '• wherewith to comfort his bowels,'' and surely he would not have prescribed a crude juice, or one in a state of fermentation, which takes place soon after it is expressed, for such a com- plaint as his patient was labouring under. It was wine, and nothing but wine, of which the apostle speaks, the same which, when taken in excess, he stigmatizes as a mocker. We are, moreover, told that new wine must not be put into old bottles, lest they should burst in the process of fermentation. Leather bags are of course here implied. We are mistaken also, if there be not some such phrase as that, Wine is made to gladden GERMAN PRACTICE. 283 the heart of man. It was not the mere juice of the grape wliich our Saviour supplied at tlie marriage of Cana, when, in its conversion, " The conscious water saw its God and blush 'd'." Nor can there be a more decided argument in favour of the use of this liquor in moderation, than this very circumstance supplies. That a man of education should bind himself by oath not to taste of wine or fermented liquors, is to pass a sentence of libel upon his own understanding, and to misinterpret the intentions of Providence, by refusing to accept such blessings as have been so abundantly provided for him whilst a dweller upon earth. It should be made known to teatotallers, that it is much more doubtfid whether this beverage was in- tended for such general use as the juice of the grape, seeing that the growth of the plant is so very limited on the earth's sm-face, and that this infusion may be taken to intoxication, and very often does produce more lasting and deleterious effects on the nervous system than liberal potations of wine. Those who have undergone the discipline of the grape cure for a month, are glad to come back again tu the more comfortable liquor, which, when used, and jiot abused, is often one of the greatest blessings. Erysipelas. This disease is considered very formidable by Ger- man physicians, both in its immediate effects, and as leading to results of great consequence for the future. 284 SOME PECULIAEITIES OF The treatment of it, iu its primary attack, is conducted upon purely antiphlogistic principles, as regards in- ternal remedies, and to the application of dry materials alone to the local afl'ection. The application of any- thing in liquid form to the part is most severely reprobated; and a practitioner who would apply a cooling lotion to a leg with erythema (in common language, the rose), would risk the censure of the medical Board of Control. There is a great and insuperable fear universally prevalent amongst Ger- man physicians of repelling anything in the form of eruption ; and should this have been done, it seems sufficient to explain the production of any subsequent malady at any future period, however remote it may be. The blood, once contaminated by the retrocession of an eruption, will require quarts of decoction to purify it. Fevers are attributed to the use of Gowland's lotion, as surely as puerperal mania and phlegmatia dolens are ascribed to the absorption of milk into the blood. The rose is looked upon with a jealous eye, both as to immediate and future consequences ; and a patient who has once suffered from erysipelas, is hardly considered out of jeopardy for the rest of his life. If any means have been used to cure the complaint by local applications, then the danger is quadrupled. Metastasis from the extremities to the head is held in terrorem. The treatment is confined to laxatives, sudorifics, and nauseating doses of antimony ; and the parts are dusted with starch or finely levigated chalk, with a small proportion of camphor, and the whole limb is enclosed in cotton waddinsf. GERMAN PRACTICE. 285 If the head be attacked, a mask of this material is made to envelope it, apertures being left for the eyes, mouth, and nostrils, so that the patient has the look of a Spanish inquisitor. In the plan of treatment here, the object is to divert to the extremities ; and the pediluvium with mustard flower, sinapisms, and dry cupping, are re- sorted to ; and this with increased hopes of success, if there be the slightest probability of gout in the system. I have never known bark administered in this affection, nor are opiates allowed in any stage of the disease, even after the departure of all unpleasant symptoms, and when sleep is but the one thing w\an ting. In an abridged sketch of the history of medicine in Russia, published in the first or second volume of the Quarterly Medical and Surgical Review, it will be seen that the failure of Dr Leo's treatment of the son of a Czar for this disease in his leg, led not merely to his disgrace, but to his execution. I once witnessed erysipelas attacking the scrotum, and running into gangrene in forty-eight hours. One- half of the bag sloughed away, leaving the testes quite denuded. Bark and wine in large and repeated doses, with opium, arrested the progress, and the patient recovered. He was treated by Saloman and myself. The patient was a young man of dissolute habits, who led a hard life, and was much addicted to drink- ing. He had been exposed to very severe cold, after getting wet through and standing in the water. A twelvemonth after this period, he was again under my care for erysipelas of the head, from which he re- covered without any severe symptoms. He was 286 SOME POPULAR REMEDIES OF alarmed about his health after these two attacks of illness, and left the country. SOME POPULAR REMEDIES OF THE GERMAN SCHOOL. Muriate of Ammonia. Previous to my sojourn in Russia, 1 had never seen this remedy employed otherwise than in the form of lotion. I have, within the last fourteen years, had much experience of it as a medicine, administered inter- nally, and have had very convincing proofs of its effi- cacy, or even preference, over other, salts in a variety of complaints. I have stated, that although tuber- cular disease is comparatively rare in high northern latitudes, yet pleuritic affections, subacute, and con- gestive inflammation of the lungs and their envelopes, are of frequent occurrence. These are the effects of vicissitudes of temperature on the breaking up of the winter, and go under the name of refroidissement, a term which implies something more than our English phrase of catching cold. In cases of serous and mucous congestion, Avhere the inflammation does not run liigh, I have seen this salt employed with the most beneficial effects. In pleuritic affections it is usual to combine tartarized antimony with it, and the following is the formula in general use : — B Ammonia? Mur. 3j. Antimon. Tartar, gr. ij. Decoct. Glycyriz, gvij. Syrup. Altheai gj. Mft. haust. THE GERMAN SCHOOL. 287 A table spoonful of this is given every two hours, and continued in spite of the nausea and occasional vomit- ing, which the fevr first doses seldom fail to produce. When prescribed by itself with the same view as nitrate of potash, I should, as far as my own expe- rience is concerned, give it a decided preference. It is hardly Avorthy of the dignified title of a specific, nor is its deobstruent power so great as its advocates maintain. It acts slightly upon the kidneys, and ex- pectoration is often facilitated but not always so, and cases treated by it progress to cure without decided critical evacuation. In cases of congestion of the mucous membranes in chronic sore throat, with elongated uvula, and flabby state of the tonsils and parts about the fauces, it is very beneficial. In that condition of the mucous membrane of the stomach, caused by the action of a variety of medi- cines, and which gives rise to anorexia in convales- cence, I have seen it employed with happy results. The tongue loses its pallor, and acquires a healthier appearance under its influence, and it paves the way advantageously for more decided tonic remedies in the convalescence after gastric fever. In some forms of uterine disease, accompanied by discharges, it is also useful. Its salt unpleasant taste is best disguised by liquorice root in form of decoction, or by a solution of the extract in water. Generally, after the first few doses, patients take it without disgust. Nitrate of Soda. I have already stated that the Germans consider 288 SOME POPULAR REMEDIES OF this salt of a more antiphlogistic nature than the nitrate of potash. Muriate of Soda. This, in the form of brine in which cucumbers are preserved, is a most popular aperient. A small watery seedv cucumber is preserved in salt and water, to Avhicli a very small proportion of vinegar, and some leaves of the black currant-tree, are added. Thousands of barrels are so prepared annually, and serve as salad for rich and poor during winter. The liquor, impreg- nated with the rhind of the cucumber and the leaves of the black currant-tree, is drunk in tumbler doses, and seldom fails in the desired effect. Bitter Wasser. This is more generally used in St Petersburg than any other purgative. It is imported from Germany in stone-bottles. Its action is mild and speedy. It is taken fasting, in half pint or pint doses. Its taste is mawkish. Previous to a commencement of a course of mineral Avaters, it is customary to administer a few doses of this to prepare the way for them. Pregnant women use it with very great advantage, for it pro- duces all the desired effects without causing griping. It is a Carlsbad water, and the active ingredients are the sulphates of soda and magnesia. The Pulna water is the best substitute I have found for it in this country, but it is not by any means so certain in its effects. THE GERMAN SCHOOL. 289 Phosphoric Acid. This is given in all those cases where British practi- tioners employ sulphuric and nitric acid. It is pre- scribed in its solid form, in pills, but more frequently in the liquid state, and is considered to possess more tonic j)Owers then the two former. Acidum Mariaticum Oxygenat, (Chlorine Water.) Is a favourite remedy in putrid fevers, and in cases of ulcerated sore throat, which assume a putrid form. It is useful in gargles, and I have used it with much advantage in St Petersburg, where sore throats are very prevalent, owing to the alternations of extreme cold and moisture which prevail in the spring and autumn. It is best gi^en by itself in drops, from thirty to fifty in water. Sugar decomposes it. I have used it with decoction of bark. Tlnct. Digital, ^ther. This is a very useful preparation, and a convenient mode of administering this remedy. The leaves of the fox glove are macerated in sulphuric aether in lieu of proof spirit. The nauseating properties of the digi- talis are counteracted by the stimulant power of the menstiamm, and, in cases of serous effusion, where it is desirable to increase the action of the absorbents, and to determine to the kidneys, this preparation seems to combine these advantages without producing the o 290 SOME POPULAR REMEDIES OF nausea and exhaustion which frequently accompany the use of the simple tincture. Aqua Lcmro-cerasi. This preparation is in much and deserved esteem in Germany. Dr Malfatti of Vienna has used it more frequently than any other practitioner, and no con- tinental physician has been more consulted in ner- vous complaints. I am surprised to find it so rarely employed by London medical men. It is highly serviceable in spasmodic affections, and it is what the French style a calmant, in the most extensive sense of the term. It is prussic acid chawn mild, but it is more available in practice, and indeed is almost used to the exclusion of it by continental physicians. It is a safer prepara- tion — the dose may be increased from ten to sixty drops, and a patient may be trusted with a phial of it. The aqua lauro-cerasi deserves a trial. It is most useful in spasmodic affections of the stomach, in hypo- chondriac uneasiness, in hysteria, w^here there is un- easiness about the uterus. The late Dr Sutoff of St Petersburg gave it in very large doses in puerperal mania, where there was manifest uterine irritation. In such cases, he considered it a specific, and gave it in table spoonful doses. In nervous palpitation of the heart I have found it most signally efficacious. It relieves the pain caused by inspissated bile, or small calculi passing through the ducts, more speedily than any other remedy with which I am acquainted. A near relative, continually suffering from this cause, THE GERMAN SCHOOL. 291 generally found immediate relief from it. Pie has passed very large calculi at different periods. There is no medicine with which I am acquainted varying so much in its virtues from difference in the mode of its preparation. I have not found it of equal strength in any two chemists shops. A preparation of the bitter almond is often substituted for it, but is far inferior to it. The distillation of the fresh leaves of the Pruno lauro-cerasus is the medicine to which I allude, and I have found it no where so good as at jNIessrs Hudsons' in the Haymarket. As, upon my return to England, I had not, for some time, sufficient opportunity of ascertaining whether all the effects which I had witnessed abroad from the use of this medicine, Avere not to be procured from the more concentrated hydrocyanic acid of Scheele, I could not state my opinion so decidedly as at present; but from the few cases which I have since treated, I may aflSirm that the aqua lauro-cerasi is by far the more effective preparation of the two. In many nervous affections, as palpitation, hysteria, &c., I generally prescribe the following draught : — R Aquae lauro-cerasi, vri xx. Aqua3 Flor. Aurantii 3j. Syrup. Tolutan 3j. Mft. liaust p. r. n. s. The French often prescribe a concentrated prepa- ration of the orange flower in sugar and water for spasmodic uneasiness about the stomach, — for indi- gestion arising from repletion. 292 SOME POPULAR REMEDIES OF Arnica Montana. This has been lately introduced into British prac- tice. Whether it is held in much estimation by the faculty here I am unable to state. With the Germans it is classed among sacred remedies. Its virtues are extolled throughout two pages of the " Pharmacopoeia Ruthensis." I have been much disappointed in its effects, as far as I have been conversant with its use. It is gene- rally used in cases where strychnine is indicated, but it is much more uncertain in its operation. I have known it exhibited in large doses, without producing any sensible eifects. Indigo. This remedy I have seen administered in cases of epilepsy, hysteria, and also in all the convulsive dis- orders of children, from such as result from difficult dentition to those which are caused by effusion on the brain. I have ever protested against the idea of the pos- sibility of its doing any good in such cases, and have discontinued my attendance where a continuation of its use has been insisted upon, to the exclusion of really active remedies. It is, nevertheless, a very popular one with German physicians. As, in olden time, the madder root was prescribed in virtue of its colour for scanty menstruation, 1 believe the blue indigo appearance of the mouth and face in THE GERMAN SCHOOL. 293 convulsive attacks has, upon some homoeopathic prin- ciple, led to the belief that this drug Avould be useful in such affections. It may be said in this instance, with much truth, " Nimium ne crede colori."' lulix Mas. ^ This is a popular remedy for worms. A German practitioner told me that he found the male fern alone possess the power of expelling the tape-worm, and that want of success might generally be attributed to the employment of the female plant. Extracts. Vegetable extracts form a large item in German prescription. The two favourite ones are the ext. taraxaci, and the ext. graminis (tritlcum repenx). The former is employed in hepatic affections, jaundice, dropsy, &c. The latter is used as a mild tonic and deobstruent in the convalescence of fever. Perhaps no two remedies are so frequently employed as the two in question. Their indigenous growth is one of their principal merits. The llussians, as far as drugs are concerned, patro- nise home produce. They have a prejudice against taking such as do not grow in the quarter of the globe in which they reside, and question the influence of Asiatic products upon European constitutions, unless the latter happen to be I'csidcnt in Asia. 294 SOME POPULAR REMEDIES OF The domestic medicines of the people, the roots, the herbs, the simples, are much in vogue with the higher classes, from the cu'cumstance of their indige- nous growth. Many of these are employed in hospital practice. As a diaphoretic, the infusion of the dried raspberry, or the flower of the elder, answers the purpose very Avell in cases of catarrh. Juniper-berry tea, and parsely-root tea, are some of the commonest diuretics, or serve as menstrua for other powerful remedies of the same class. The flowers of the lime-tree are sup- posed to possess very soothing powers, Lime-flower tea is much in vogue. The species jyectoral is com- posed of a variety of herbs, the violet or pansy, the borage, the coltsfoot, the horehomid, &c., &c. ; and in all cases of catarrh, ptisans made with these herbs are in great esteem. Ox Gall. If we look into the histories of past times, and analyse the views of our ancestors respecting the operation of medicines, we shall find that there is no- thing new in homoeopathy. In the prosecutions by the College of Physicians of those dealers in medicines who used to adulterate their drugs, we find that sheeps lungs were often substituted for foxes' lungs, and the bones of horses' hearts for the bones of stags' hearts. As the fox is a long winded animal, and can run for a long time without being out of breath, so his lungs dried and powdered were supposed to be efficacious in the treatment of asthma and dyspnoea ; and as the THE GERMAN SCHOOL. 295 stag is said to be subject to epilepsy, his heart's bone was administered against this disease. Much of this still remains to be weeded out of German practice. In cases of prolapsus uteri it is the custom with some to fill a bag with cascarilla, make it warm, and apply it high up on the abdomen ; and surely this savours of the old idea of drawing the womb up by the odour, as when it got into the throat it was the object to draw it down again into the globus hystericus ; nor can I see what virtue the fuligo sjylendeyis, which an accoucheur considered as a specific for this affection, can have, unless the propensity which soot possesses to fly up the chimney. Upon the same principle, then, is the gall of the ox universally adminis- tered in all affections of the gall bladder, either where the bile is inspissated, or where calculi are formed. It is a powerful bitter, and may be of service as a tonic, but the idea of dissolving gall stones upon such homoeo- pathic principles, is rather ancient. Dr Baillie main- tained that there was no solvent for these in the living body. It may remain for galvanism to do something with them. Where there is a suspicion of biliary calculi, this resinous matter is very generally pre scribed. Oleum Jecoris Aselli. This animal substance, one of the most unpalatable in the whole list of internal medicines, has been much used of late in scrofulous cases, and is reported to be efficacious in strumous affections. I have not sufficient experience to state anything decisive as to 296 SOME POPULAR REMEDIES OF its merits. I have seen it given to very young children ; but the dislike and disgust to its taste have generally produced more disquiet and uneasiness than any good Avhich might otherwise have been antici- pated from its use. When the horror of a medicine will well nigh throw a child into convulsions, and ■when this has to be repeated several times in the course of the day, little good can be anticipated from its specific powers. This is a part of German practice which appears unnecessary, viz. the constant repetition of the dose. It is common to givo small quantities of active matter, and repeat the dose every hour in most cases ; so that the nausea and disgust of one potion is hardly got rid of before it is renewed by a second ; and is it to be wondered at if homoeopathy should triumph over such practice ? I made this objection once to a German physician, whom I often met in consultation. He replied to me, True, but when I order a medicine to be taken five times a day, I may hope that it wall be taken three times. It is not necessarv to go abroad to prove that regiments of phials are never uncorked by the patients ; and it is often from the fear of being compelled to take so much, that the good which a little might do is often refused by the patient. The system certainly is fundamentally bad, as it is, or rather was, once prac- tised in this country. "When one thing is substituted for another, it is never done so with impunity. No two things are precisely alike, as no two words are perfectly synonymous. If labour and talent are to be charged upon drugs, it must follow that both patient and practitioner will eventually suffer. The former TfiE GERMAN SCHOOL. 297 "^ill refuse the quantity altogether ; or, in case of a second illness, will, from fear of the same system being pursued, defer timely application, when a little medi- cine might be of great assistance; and the practitioner will suffer in his reputation, and lower the dignity of his profession to a trade. There are few who will not uphold me as to the truth of this statement, and Avho earnestly desire some other method of remuneration than that, which they are almost by law compelled to exact, upon this substitutive system. This should be the basis of medical reform ; — to place the profession upon the standard of truth and respectability; — to allow practitioners pecuniary remuneration for their time and talents, without being under the necessity of charging these upon a superfluous supply of drugs. To remedy this, the plan naturally suggests itself, of separating the prescriber from the dispenser of medicines, and this would do if men were perfect ; but a system of collusion may here creep in, and the patient have to pay as much for his drugs, and receive them in as large quantities from the simple dispenser as from the compound apothecary, of which I have seen too many instances abroad, where the physician does not dispense, but has a per centage allowed him for his prescriptions. The temptation is often irre- sistible. Nay, I hare known tiiat, in many cases where practising among a poor but respectable class of society, unable to afford a fee, he receives no other remuneration th:m what he takes from the druggist, who dispenses only for ready money ; and thus the patient is as much nauseated by quan- 298 SOME POPULAR REMEDIES OP tity as by a simple DOSE of the Oleum Jecoris ASELLI. There is an art in prescribing. It cannot be donbted that many remedies would work better upon the system if they did not excite that nausea and disgust, which cannot be nugatory as regards their effects. Thenerves do not bear it with impunity, and remedies are shorn of their natural powei's by this very cu'cumstance. We may instance the capivi capsules as forming this de- sideratum ; for many a stomach has revolted against this balsam, in whatever other form it may have been prescribed. The Germans are in the habit of giving pills and powders in what is styled ouhli. It is a paste, such as we see on the bottom of macaroons, — a kind of wafer. Little squares of this are made for the purpose. They are dipped in water, and the pills or powders folded up in them ; and they are of so slippery a nature when thus moistened, that they glide down the throat without the slightest difficulty, and are perfectly tasteless. This answers better than gilding the pill ; for many have the greatest difficulty in swallowing these, and thus they are half dissolved in the mouth, and when of bitter ingredients, cause nausea and vomiting. Foreigners, indeed, will not take pills unless enveloped in the way above stated. As powders may be so administered, it is hardly necessary to resort to this globular method ; for a large powder may be so slipped down the throat. When insoluble substances are prescribed, there is no other way of administering them but in pills or powders. The latter must be taken in jelly ; for, if mixed with fluids, not one-half of the active ingredient THE GERMAN SCHOOL. 299 is swallowed. These inconveniences are to be remedied eftectualiy by the use of these wafers. It is better than sugaring the edge of the cup, as Tasso has instanced. " Cosi all' egro fanciul porgiamo aspersi Di soave licor gli orli del vaso, Succhi amari, ingannato, intanto ei beve, E dair inganno suo vita riceve. Gerusalemme Liberata, Canto I. APPENDIX. APPENDIX. Venereal Disease — Cancer — Credat JucIeeus — Sectio Cadaveris of a Patient dying Suddenly — Disease of Kidney — Poisons — Rupture of Gall Bladder — Puncture of Intestines — Mesmerism — Plica Polonica — Experiments on Animals. — Sound. VENEREAL DISEASE. John Hunter long since asked the question, if a chancre would heal of itself? and Broussais would have replied to him, yes, as readily as other local in- flammations, when treated upon the antiphlogistic plan. A more important question, and a more difficult problem, remains to be solved. When a chancre heals of itself, or with the assistance of some very slight local treatment, is the constitution guaranteed from future effects ? Opinions differ much upon this head, and run into very opposite extremes. A gentleman applied to me with a local sore. I told him to wash it with cold water and let me see him again in a day or two. lie did so. I then pro- 304 APPENDIX. nounced it venereal, and recommended the usual plan of treatment. Some time afterwards I met him in society, and he told me that I had been mistaken in the case, and he had got well in a few days. Six months afterwards, he came to me with secondary symptoms, sore throat and eruptions, and went through a long course of mercury. He had allowed a German surgeon to apply caustic to his local wound, which had healed. Similar cases have occurred to most who have had any practice in tliis complaint. The healing of a local sore will not prevent the constitutional effects of the poison absorbed into the system from manifesting themselves in various shapes. This is not the question at issue. The difficulty lies in being able to decide upon the true character of the local primary affection. If practitioners can be found w^ho can at once pronounce safely upon this matter, they must have very good eyes. There is what is styled the Hunterian chancre, well defined, easily recognized ; but how many more forms of wound are there which are not Hunterian, and from which all the same unpleasant consequences arise, if they are not treated constitutionally, Dr CoUes's opinions are very decided upon this subject, and very alarming; for he states that no excoriation, however slight, if healed by astringent lotions, may not prove to have been of a specific nature, and reproduce the disease in secondary forms. There is no proof wdiatever that a slight sore is not venereal, if anything more than cold water has been applied to heal it. Here, then, is at once a drawback to the value of the Hmiterian patent. VENEREAL DISEASE. 305 If we now turn to the other side of the question, we shall find that not only the slight excoriations here alluded to, but that malignant and foul ulcers will heal under local treatment, and the patient will not suffer from future consequences ; and we shall, more- over, find that both primary and secondary symptoms will be treated successfully by negative practice, — by the water cure and the hunger cure, and that thousands ofcases are dismissed from hospitals that have never undergone any specific treatment. If an illustration were wanted to prove the fact, that diseases are changed from what they were when they first appeared amongst us, the venereal disease would aiford the most satisfactory one. It is im- possible not to observe the milder forms under which it now presents itself; and true, as it may be, that the treatment is much milder and better understood, and that many of the dreadful ravages which were formerly made upon the system were manufactured by the abuse of mercury, still I do not believe that the present treatment would have been so successful, if the disease itself had not undergone some modification as well as the modus medendi. It is not to be denied that the most disastrous consequences have resulted from the indiscriminate and injudicious employment of mercury, as a medicine of universal application in this affection; and that such liave been the direful consequences of its abuses, that, in the couplet of Sydenham, " Graviora morbis patimur remedia. Nee vita tanti est vivere ut possis mori." Still all these torments were not attributable to 306 APPENDIX. merciiry alone ; and from all that we have seen and gathered from our medical brethren abroad, both for and against its employment, we are far from being converts to the new system, and still look upon the mercurial treatment as the safest and most satisfactory method of combating the venereal disease. When in Stockholm in 1842, we had an opportunity of visiting the large military hospital in that city, and of seeing a great number of patients treated upon the antiphlogistic system, where no mercury was used ; and, upon inquiry as to the appearance of secondary symptoms, we were informed, from the statistical tables, that the number of patients so infected gra- dually decreased as the plan was more generally adopted, and that they did not, during the last year, average more than seven per cent. In Berlin we found that the results were very different, and that the cases of secondary symptoms w^ere very numerous ; and Dr Diefenbach himself informed me, that he had abandoned the non-mercurial plan, as he found that it was both more uncertain in its final results, and the constitution of the patients was much more shattered by the abstraction of nourish- ment almost to starvation, than by a moderate use of mercury and a moderate diet. I had, however, an opportunity, to me most desir- able, of visiting the military hospital at Stockholm on admission day, so that I could judge of the natm'e of the local affections, before any plan of treatment had been adopted ; and this at once convinced me of what I had ever presumed to be the case, that however ex- cellent such treatment might be, it was often employed VENEREAL DISEASE. 307 in cases where no venereal affection really existed, and thus usurped a reputation which it could not legiti- mately claim. I was accompanied by Dr Smith, a most intelligent English physician, residing at Stockholm, and we saw the patients together, who were just ad- mitted into the venereal Avards. Of these — some had phymosis and paraphymosis ; others, clusters of sores round the edge of the glans penis, excoriations of the prepuce from uncleanliness, excrescences of doubtful character about the anus, and there were not more than two or three at the most, out of eleven whom we examined, who would have been subjected to mercurial treatment by any well-educated British practitioner; yet, these cases, eight out of the eleven, all perfectly tractable by baths, purgatives, and cooling treatment, for which a mercurial course would have been criminal, subse- quently, no doubt, figured in the numerical lists of patients treated without mercury for syphilitic affec- tions. The plan adopted in this hospital is much the same as in Hambm*g and Berlin, or wherever the disease is treated upon this idtra antiphlogistic plan. Great precautions are taken to prevent any fermented liquors being smuggled into the wards ; for, not only are the doors barred and bolted, but a lock is put upon tlic key hole, to prevent even a quill from being in- troduced, so much addicted are the Swedes to the abuse ofspirituous liquors. Baths, saline purgatives, and a diet of weak tea, and a small proportion of white bread, form the whole of the treatment, and the most aggravated cases are said to yield in from five to six weeks. It is doubtful whether these most 308 ArrENDix. aggravated cases do not get well sooner than those whose appearance is much more simple, for the very circumstance of a sore being bad at the commence- ment in its appearance, is often proof that it is not decidedly syphilitic. It cannot be denied, however, that what bears all the character of a venereal ulcer, will get w^ell by this plan of treatment ; and the only question that remains to be agitated, Is it preferable, and in what respect is it so, to a mild mercurial one ? The advocates for its adoption, admit that the former plan is not more certain than the latter ; and as to the objection to the havoc which mercury makes upon the constitution, it is admitted that patients are much more exhausted under the new, than under the old method. As to the question of secon- dary symptoms, it is difficult to get at the truth. Eruptions may arise from a variety of causes ; and pains in the bones are rheumatic ; but upon a fair investigation of the matter, it will be found that a regular mercurial treatment, well directed, is a surer guarantee against subsequent effects on the system, than where this specific is dispensed with. In the Berlin hospital, the cases of secondary symptoms are very numerous, and many of the Prussian practitioners have abandoned this mode from this circumstance. Another and material objection to this system is, the impossibihty of employing it except in those cases where the patients are wholly under the control of the practitioner. In fact, it is confined to the wards of a Lock Hospital. A debauch is more prejudicial in the uninterrupted antiphlogistic j)lan, here insisted VENEREAL DISEASE. 309 upon, than any other ch'cumstancc; and reliance cannot be placed upon mdividuals ; nor is it to be supposed, that for the slight inconvenience under which they may suppose themselves to labour, they will adhere literally to the plan laid down for them, and not yield sometimes to temptation, where this, moreover, cannot in their minds be associated with excess. In the opportunities I had of seeing this plan adopted in St Petersburg, I found that it was con- fined to a very few, and to the hospital practice only, and this upon no very extensive scale, for the lower orders are little subject to the disease ; and the class which does suffer, is not one that readily submits to the discipline of an hospital. In those cases where it M'as employed, the same report was made of its success, as in the Hamburg establishments. I shall not enter into any details upon this matter, as a fidl account of the plan of treatment is to be found in Sir Alexander Chrichton's late publication upon fevers, from which I have already freely quoted ; and it Is cheering to find a man, whose career was so brilliant, and whose moral character stood so high in the Russian capital, still labouring In his vocation with all the energy and ability of the maturest of his days. It is also an objection to this new system, even under circumstances where the plan is fully maintained, that the class of patients suffer too much from Its debilitating effects. Tradesmen and mechanics have not much stamina, and can ill bear a diminution in the quantity of food, of which they can hardly procure cnoTigh by their healthy labour. How arc they to make up for the loss of nutritious matter when dlcj- olO APPENDIX. missed from an hospital, weak and emaciated, witli no money at command, and no strength to work ? They are placed in the anomalous situation of having no means tUl^they gain them ; and being unable to do this from lack of physical power. On the other side of the question, we are much in- debted to this system for the knowledge which we now possess, that mercury is not absolutely necessary in the treatment of Lues Venerea ; for we have abundant proof, that every stage of it, from the simple primary idcer to all the protean forms which it afterwards assumes, in the shape of eruptions, nodes, &c., is curable by simple treatment ; and as we occasionally meet with those whose constitutions will not bear the impression of mercury, we may congratulate ourselves that we have other means at our command. Upon this subject the profession has long been all abroad. When secondary symptoms appeared after a mercurial course, it was, in the olden time, attributed to an insufficient dose of this mineral, and another course of it was commenced de novo. Now, the very same symptoms are attributed to the modes of cure which were formerly ascribed to the indomitable character of the disease ; and notwithstanding all that has been said upon the matter, nothing will prevent their appearance in some peculiar constitutions. Still, I am of opinion, that whilst we in conclave have been discussing the nature of this malady, and the various modes of treating it, the disease has taken the opportunity of changing its nature, and of losing its malignancy ; nor do I attribute this to a change in the treatment onlv, for, be it remembered, that there are VENEKEAL DISEASE. 311 still some practitioners of high eminence, who employ- it as freely as aforetime, and who will not listen to any other doctrine than that of the mercurial. Dr Colles of DubUn ranks perhaps foremost in this list, and prescribes a month's course of mercury for a })rimary sore, and insists that during three weeks out of the four, the patient's mouth should be thoroughly affected. Nor does a scrofulous constitution, according to this author, forbid its employment, but it should, on the contrary, be pushed to ptyalism, by which alone its healthy action is produced. We do not meet with anything more decisive than this in all that has been written in its favour ; and such doctrines would, with many, be accused, if prac- tically adopted, of producing all the dire effects which mercury has been said to do. That these consequences are frequently unjustly attributed to the use of the latter, is a matter of occa- sional occurrence, and I had, myself, an opportunity of knowing an instance of such defamation. A young man of dissolute habits had been frequently annoyed by primary sores, which he had always ti'eated himself by caustic ; and when bubo succeeded to them, he used to apply leeches very freely. He had done so for years, when suddenly he broke out all over in one mass of sores, from head to foot. He then, and not till then, applied for medical assistance. Five grains of blue pill were given him night and morning for three or four days, when he became maniacal, and the pills were discontinued, and no more of the mineral was employed. As soon as circum- 312 ArPENDIX. stances permitted, he was conveyed to England, almost a putrid mass. I know not mider whose care he was placed, but his state was attributed to the abuse of mercury, of which he had taken, at the most, twelve or fifteen grains. This circumstance was noti- fied in the history of his case, which was read to the person under whose care he was placed in England. He finally recovered, but remained a wretched object. Before speaking of the mercurial treatment of this complaint, as practised in Russia, and it must be borne in mind that this implies the German Faculty, I may mention some points which have afforded more matter for controversy in England than in the north of Europe. In my Lehrzeit, or the days of my medical stu- dentship, the idea of the complaint being propagated by sexual intercourse, where no external symptoms were at the time manifest, was altogether ridiculed by the heads of the profession. Mr Pearson began to waver upon the matter about the year 1820, and finally, I believe, changed his opinions in toto upon this important subject. Now, what is the general idea ? Not certainly that it is not the case, but a mat- ter of wonder that there could ever have been doubts upon the subject. Dr Colics now mentions, " Infants are infected In utero by parents, both of whom are, and have been, pre- vious to marriage, in a sound state of health, but one or both of whom have had venereal symptoms, which they supposed to have been eradicated previous to marriage. These cases have been proved, by repeated abortions of diseased, and, generally lifeless, children ; VENEREAL DISEASE. 313 and again, an infant afFected with secondary symptoms may infect a dry nurse -who handles it, and who, thus gaining sores, may infect another sound child whom she may subsequently handle. It is singular that a syphilitic infant never aifects the breast of its own mother, although it immediately affects the nipple of a wet nurse. This infection may easily be propagated through a whole family, and is not less contagious than the itch." — Colles on the Venereal Disease. Now these are opinions which may be supposed to savour of ultra notions, and would not have passed current some thirty years ago, but they are those which have ever been adopted by the German school, and the question with them is as to the time that a syphi- litic taint may remain in the constitution without being wholly eradicated, and so capable of propagating its effects. I should say that Germans will prescribe no limit to such cases, and that with them the period is indefinite. Sir Astley Cooper maintained that if a patient were free from any outward and visible sign of the disease for two whole years, any subsequent suspicious symptoms which might afterwards manifest themselves, could not be attributed to the consequences of the primary affection. The Germans would lay down such a law as the following : — " Although the probabilities are much against the reappearance of syphilitic symptoms where there has been no manifes- tation of such for an interval of some years, still there is no standard by which m'C can judge of perfect immunity from such ; and the circumstance of their having lain dormant for a long period, does not negative their specific character Avhcn they reappear." The same r 314 APPENDIX. reasoning applies to gonorrhea as to lues, and I have known an erythematous affection of the leg attributed to a simple clap, from Avhich the individual had never experienced any inconvenience for five or six years. The state of health of wet niurses, is a matter of very great importance, and involves professional reputation. As regards their choice in St Petersburg, not a spot must be found uj^on their skins ; a flea bite is equivocal, and any disease which a child might have in after life would be ascribable to a pimple, if such had really existed upon the wet nurse's cheek. Thus they have to pass through a very critical medical ordeal before they are furnished with certificates of qualifica- tion for their important offices. They are chiefly the young wives of peasants. They are well paid, clad in sumptuous apparel, treated in the kindest mannei', for the Russians understand the influence of the nerves over the secretions, and do nothing that shall excite angry passions in the nurse. They naturally choose, as far as they are able, the best tempered women. The accoucheurs prefer a woman whose child is three months old to one who has just been confined, and the mother of a second child is preferable to a novice. It is, however, an unjustifiable system, for no heed, — no care is taken of the poorer offspring, who generally falls a sacrifice in the first few weeks. This is often concealed from the mother, from no particular anxiety about her feehngs,but from fear that any shock to them might give a colic to the parasite. There is no doubt, as Dr Stevens has remarked, that these diseases are communicated to cliildren by mothers and nurses through the medium of the blood. The VENEREAL DISEASE. 315 lues venerea and variola afford ample proofs ; and upon the authority of Dr Lind, the same author observes that agues are so transmitted. This is much more problematical. The secondary affections are, according to Dr Colics, capable of generating primary symptoms, as ulcers on the tongue and lips create chancres in others. The following is related by the same author. " An ac~ couchem* got a sore upon his finger in his obstetric practice. He took mercury, and the sore healed. Upon bruising liis finger two years afterwards, the sore broke out again, and proved to be of venereal character, as it communicated the disease to two females whom he attended in labour." The posif hoc, propter hoc, does not seem evi- dent in this case. The practitioner was in the habit of attending the lowest orders of females, as is evident from the statement. He gained the first sore in this way, — when his finger was bruised : what reason is there to suppose that he did not gain the second sore in the same way as the first without having recom'se to the idea of the disease being again revived by an accidental bruise. This is, of course, only matter of conjecture ; the authority is too high to allow us to suppose that all circumstantial evidence has not been fully weighed ; but I, and I venture to say many others, have known of men being Infected by females in whom no trace of the disease could be discovered. A very promiscuous intercourse may account for such an occurrence. I shall now state the general plan of treatment pursued by the German faculty iu this complaint, 316 APPENDIX. wliere mercury is employed, and state my reasons for adopting their system to a certain extent in the general, but never in the local, plan of treatment. Much of what I am now about to reproduce has already appeared in the Lancet. It is customary with German practitioners to apply caustic immediately upon the discovery of a local sore ; and this is done very effectually, not merely touching the surface with the nitrate of silver, but burning it deeply in, so that a considerable slough afterwards separates, — and with this is eradicated the local disease. If this be done in time, it may answer very well, but it is difficult to say what is precisely the meaning of doing it in time ; for however soon the local sore may have been discovered, (and this is a point also of importance, for a local sore may exist many days before its nature is suspected,) still ab- sorption may have taken place into the system, so that the practice can never be considered as safe. This, however, prevails very generally, and it arises from the difficulty of persuading those who are so affected (for the most part militai-y men) to undergo a regular treatment. They cannot imagine, that for a local inconvenience so trifling in itself at the com- mencement, they must abstain from all their usual habits ; and as the mercurial treatment, where judici- ously administered, is slow in its operations, and makes no impression upon the local affection for some days, they lose patience, apply elsewhere, and it is seldom that they do not pass through the hands of several practitioners in the course of the treatment. If, therefore, the local affection be thus timely taken, VENEREAL DISEASE. 317 it is eradicated by caustic in the first instance. If a sore is decidedly venereal, and the patient is aware of the nature of the disease, and disposed to submit to a rational plan of cure, the following mode is gene- rally adopted. A simple purge and a w^arm bath take the initia- tive. The black wash is used locally, and the bichlo- ride is given internally upon the following plan : — ft. Hydrarg. Bichlorid gr. iij. Solve in aqua fontan nx ij. Ext. Glycyrrhiz 5ss. Opii Puri gr. iij misce et distribue in pilulas xviii. Kquales. The patient commences by taking one pill the first night, and one the following morning. The same the second night and morning. Two pills the third night ; one in the morning. The same the fourth and fifth night. The sixth night two pills, and two in the morning. Three pills on the seventh night. Thus the dose is never pushed beyond one grain of the bichloride in the twenty-four hours, and seldom more than two-thirds are administered. If thinti-s o-q on well, and the disease feels the influence of the dose, this is diminished in the same ratio that it was auf- mented, and the plan of treatment usurps the title of the montant and the descendant. A pint of the simple decoction of sarsaparilla is taken daily, and, in most cases, it is found that the cure is eflf'ected towards the end of the third week, or after from ten to twelve grains of the use of the 318 APPENDIX. mineral. The treatment is terminated by an aperient and two or three warm baths. In the dietetic part the patient is put upon a low diet, and but a small quantity of animal food is allowed, and white meats only. Wine and fermented liquors are prohibited by the generality of practi- tioners ; but some allow a moderate quantity of the former upon the principle of its preventing the debi- litating effects of nausea, and alleviating tormina; but this is not the general practice. Coffee is considered too stimulating, and all condiments in the preparation of the patient's food are prohibited. As a general position, the more simply the body is nourished, the more powerfully will specific remedies act upon the disease under which it labours ; there Avill be less chance of chemical decomposition, and this theory, rational in itself, is supported by facts. There is a difference of opinion among German prac- titioners as regards the advantages or disadvantages of cutaneous perspiration during the administration of mercury. Some advise that the patient should be con- fined to a room heated to 60° Fahr., and combine sar- saparilla with the mineral from its sudorific properties ; whereas a distinguished physician in Vienna, who has acquired celebrity for the treatment of syphilis, par- ticularly under its secondary forms, insists upon a cool surrounding atmosphere, asserting, that if the pores of the skin are kept open, mercury loses half its power. In St Petersburg, the former opinion prevails ; and in no chmate do these diseases more readily yield to the influence of mercury than in these northern lati- tudes, and more particularly in the winter season. VENEREAL DISEASE. 319 The equable temperature of the apartments prevents the patients from catchhig cold, and the dryness of the atmosphere allows, under certain restrictions, of moderate exposure to the open an-. It is true that the treatment is prolonged by exter- nal exposure, but it is equally true that the constitu- tion on the whole suffers less than when subjected to close confinement. AVhen it is the object to introduce mercury by slow degrees into the system, either the bichloride is given as above stated, or frictions are employed ; the latter arc, however, gradually going out of use. AMien employed, a severe discipline as regards confinement to an equable warm temperature is strenuously enjoined. I must state that I was much disappointed in the effiscts of our English preparation, the blue pill, in northern latitudes ; and the failure must be attributed to some peculiarity in the climate, and not to the preparation of the medicine, for I imported it from the best London chemists ; but not finding it successful, I invariably employed the bichloride in the treatment of equivocal complaints during the latter period of my residence in Russia ; and adopting the plan which I have above notified, I may say that I have had no secondary symptoms to deal with Avhere it was con- scientiously followed by the patient. I have, in some cases, where I was persuaded that ihe moie gradual treatment would not be persevered in, affected the system rapidly and puq)osclyj as the only M-ay of commanding the future treatment. As soon as once the mouth is aflfccted, the patient is aware of the dangers which he incurs by imprudence, and thus 320 APPENDIX. becomes docile ; but this plan is one of necessity and not choice. In some constitutions, which rebel against a continued use of mercury, the hydriodate of potash is substituted for a time. It is generally given in ten grain doses three times daily, with the simple decoc- tion of sarsaparilla. If the local condition of the part improve, and the constitutional irritation cease, the mercury is again resorted to for the final cure. This constitutes the basis of treatment for secondary symptoms : Small doses of the bichloride, with the hydriodate of potash and sarsaparilla, a low diet, and confinement to warm rooms. As regards the forms of disease, which with us usurp the title of pseudo-syphilis, the Germans hardly recognize them. They divide affections of equivocal character into sexual and mercurial. If they belong to the former class, they are supposed modifications of syphilis, and treated as such; the latter are not often met with, for mercury is never pushed to any great extent. In syphilitic eruptions the nitric acid bath is a favourite remedy, as is the acid given internally. I have seen few ravages made by the disease in this country. Of the surgical treatment it is not within my province to speak. Buboes are generally allowed to burst spontaneously; and the general opinion is favourable to them, as guaranteeing the system against all future consequences of the primary affection. An old practitioner told me that he had once to deal with a very obstinate case of ulcer on the cheek, which would not yield to any preparation of mercury, VENEREAL DISEASE. 32 X and he cured it by the sulphate of copper in small doses. In the cases which came under my notice, I had little difficulty with them ; and when I abandoned the blue pill and substituted the bichloride, the difficulties became still less ; which leads me to think that the disease itself wears a milder aspect, and it is certainly among the number of those which is not aggravated by the influence of a cold climate. In the employment of the bichloride, the advantage is considerable as regards exposure to the open air during its administration ; but this is counterbalanced by a longer process of cure ; and I am still a firm adherent to the old plan of administering mercury, where it is the object to affect the system gradually by inunction. This old fashioned practice claims many privileges, and has nothing against it but the disagreeable process of application, and the confine- ment which is imperative under its use. By this means the system is surely and certainly affected, almost in a given time, and to a given amount ; this may be increased or diminished at pleasure. Nodes, buboes, all give way under its influence ; nor are the mucous membranes of the stomach and bowels dis- ordered in the same way as in the genteeler methods. 322 APPENDIX, CANCER. This disease is by no means rare in Russia, and attacks the female breast very vii'iilently. I have seen several cases of single Avomen thus affected, and all sank under the disease. The plan of pres- sure instituted by Mr Yonge, I found still in opera- tion in the Russian hospitals, and I ventured to assert, that it had been long smce abandoned in this country, for it was found that the seeming advan- tage arose from the absorption of the sound part of the breast, whilst the diseased structure was not in- fluenced. I never heard of a case being cured by it in St Petersburg ; and after the patient had gone through all the inconveniences of it for months, the treatment generally terminated by the knife. As regards the subject of operation, there is a difference of opinion, but the leaning of the faculty towardsnon-interference, certainly prevails. My friend, Dr Saloman, told me, that he would never operate again, where the disease was fully formed, for he had never known a patient finally recover under such cir- cumstances. In all schirrous affections, iodine is a favourite remedy, combined with conium and local applications of the same materials. The lady of a Polish nobleman consisted me in Paris in the year 1824, for a tumour in her breast, which was hard and very painful. 1 requested her to consult ISI. Depuytrend, and to make up her mind to abide by his decision. He pronounced it to be schirrous, and it was removed. Its examination after CREDAT JUDiEUS. 323 removal, was confirmatory of his decision. The wound soon healed. The result has been most satisfactory, the lady being still alive and in good health at the present period, nor has she suffered any inconvenience fi'om the breast since the tumour, which was but a small one, was removed from it. In Laennec's Clinical Wards, I remember a j^ost morteyn examination of a woman, who died with a cancer on the wrist. The liver was studded with scirrhous tumours. The lungs ^\ere a mass of scirrhus, and several tumours of the same character were found in the substance of the heart. — JanuarT/ 14,182 5. Notes. This disease is trusted to the care of empirics, as much in Russia as elsewhere; and some of the peasants are supposed to possess the secret of curing both this and scrofula. I have known several of the nobility subject themselves to the discipline of decoctions and fomentations for many months, with particular systems of diet, and some religious performances. In one in- stance I did witness the recovery of a limb condemned to be amputated, in a scrofulous child, who was sent into the country and placed under the care of a pea- sant famous for his knowledge of simples. This is the case all the world over. CREDAT JUD^US. From coUect : academ : Jean Baptiste Ferrarius Hes- perid. Lib. iii., cap. 10. In the RomanzofF Library, St Petersburg. A folio work in three volumes. La femme d'un Meunier du Bourg dc Bezendorf 324 APPENDIX. accoucha a son terme d'uue petite fiUe qui paralssoit se bien porter et qui etait tres bien conformee a I'ex- ception qii' elle avoit le ventre plus gros que dans I'etat naturel. Cette petite fille huit jours apres sa naissance fut attaqu de violentes douleurs de ventre dont on s'apper^ut bientot par ses cries continuels et ses mouvemens inquiets. Elle rendit ensuite par la vulve une eau teinte de sang apres quoi elle accoucha d'une petite fille vivante ce qui fut suivi de la sortie de I'arriere faix, et I'ecoulement des vindanges se fit comme dans un accouchement naturel. Get embrlon que venoit de mettre au monde cette petite fille nouvellement nee etoit de la longueur du doigt du milieu et comme il etait vivant et qu' il avoit la figure humaine il fut baptise, mais la petite accouchee et sa petite fille moururent toutes les deux le lendemain. CESAREAN OPERATION. When I was in Prague in 1827, I saw two women who had undergone this operation. The one from deformity of the pelvis, the other for an extra uterine conception. The latter was still in the hospital, as there was a fistulous opening remaining; the other had been operated upon years before. These cases I communicated to Mr Travers, and they were read before the Medico Chirurgical Society. I am not sure that they were printed in the transac- tions. A woman was operated upon successfully in St NEKVEN SCHLAG. 325 Petersburg, but previously to my sojourn there. She again became pi-egnant, and was again delivered in the same way. She underwent the operation twice, and recovered. I did not see her, but I state this on the authority of Dr Ai-ndt, the Emperor's body surgeon. This same gentleman performed this operation in a case of extra uterine fa}tus, during my residence in that capital, in 1839. The woman died forty-eight hours afterwards. NERVEN SCHLAG. The following case of what the German practi- tioners term Nerven Schlag, occurred to me not long before I left St Petersburg. A gentleman who had acted in an official capacity in that city, returned after an absence of many years to pay his respects to his old friends. lie had been much disappointed previously to his arrival, in some government and pecuniary trans- actions. He was attacked rather suddenly by a fit of indigestion, after having experienced for some days previous, a disordered state of bowels. He recovered, however, apparently, and was about to embark for Eng- land, when he felt himself so suddenly indisposed with severe headache, and as he styled it, pressure on the brain, that he delayed his departure. He had a good deal of fever and heat of surface, with a throbbing pain in his head. He was bled from the arm, which greatly relieved him, and he seemed better afterwards, still the headache continued, and he got little or no 326 APPENDIX. sleep. Blisters were applied to the neck, and calomel was given internally night and morning — the bowels were acted upon. The symptoms not yielding to this treatment, another physician M^as called in, and leeches were applied to the stomach — the calomel was con- tinued — the head was blistered — as the fever had greatly diminished, and the pulse was almost natural ; it was proposed to give him some opium to procure sleep and calm his irritability, which was very con- sidei-able. The following day we found him better. He had slept during the night, and had a most copious eva- cuation after the opium. This was followed by bilious diarrhoea, which lasted two days, and from this time he gradually improved. His pulse, tongue, skin, and every function, were in their normal state. His sleep was not so good as might be desired. He saw his friends, and again began to make preparations for his departure. His appetite was keen, and he wanted more than I would allow him to take. His other medical attendant took his leave, and pronounced him con- valescent. Upon the Sunday morning, about the thirtieth day of his illness, I saw him about one o'clock, and several of his friends called upon him after church. He was dressed, and lying upon the sofa. At two o'clock he ordered his dinner, a roast partridge, and felt angry that he was thus stinted by his doctor. He had written some letters in the morning. After dinner he got upon his bed to get a nap, and rang his bell ; the servant not answering it he rang again ; and when the man came he scolded him very violently. He rose in his bed to do something, and gave a shriek DISEASE OF KIDNEY. 327 I was immediately sent for ; and must have been there in ten minutes from the time he was so seized. When I got to the house he was a corpse. There were no symptoms w^hich could possibly have warranted such a termination. A post mortem ex- amination discovered considerable turgescence in the membranes of the brain ; there was no lesion, no effusion. The other viscera presented nothing re- markable. He was by nature very violent and irritable. The fit of passion was consequently the only assignable cause of the catastrophe. DISEASE OF KIDNEY. The following case is one of considerable interest, inasmuch as it proves that these organs may be diseased in an extraordinary degree, and still perform their functions apparently so perfectly as not to attract notice during life : A colonel in the East India Company's Service returned to Europe with an immense enlargement of the right side, which was supposed to be an affection of the liver, but to such a degree as seemed to me irremediable. Several eminent men were consulted, and all were satisfied with the nature of the disease ; — the fruits of the pagoda tree. I was intimately acquainted with the patient in my early days ; and he showed me his tumour when I was a student at the hospitals, telling me in joke that I might never see a finer specimen of an Indian liver. He was not much invalided by it. He took his usual exercise, rode on 328 APPENDIX. horseback, and went out shooting ; hved very abste- miously, and eked out a good old age. I believe he Avas full seventy when he died. A post mortem examination caused much astonishment to his medical attendants, for, instead of the liver being thus enlarged, it was found shrivelled up to a very small size, and a double bar kidney was found to occupy the right hypochonder. Upon putting a scalpel into it the blood gushed out to a considerable height. Notwithstanding this abnormal state of the organs, their functions must have been sufficiently well per- formed as not to have created any suspicion of their integrity during life. In my note-book I find the following : — " Kidneys ossified in woman, said to be jDetrified, and of the consistence of alabaster." — Lowenheim Memoir Aca- demique. They have been removed in animals without causing immediate death, and where both have been extirpated, urea has been found in the blood, according to Prevost of Geneva. I was once requested to assist a medical practitioner in a post mortem examination of a woman, who had suffered many years from an enormous enlargement of the liver. She appeared as large as at the full period of pregnancy. Of the treatment of the case I have no record, but examination discovered the sup- posed enlargement of the liver to be an enormous scirrhus of the uterus. The liver was much less in size than under natural circumstances. In the first edition of Dr Mason Good's Study of Medicine, the liver of a patient affected with dropsy poisoxs. 329 is stated to have weighed 628 lbs. I do not find this paritgraph in the subsequent editions. POISONS. The mode in which these agents are introduced into the system, and the medium through which they act, have given rise to much discussion, and do not hitherto seem to be satisfactorily determined. It was with a view to prove venous absorption that Magendie's apparently conclusive experiment was instituted, when he applied poison to the foot of an animal, separated from the trunk by all but two quills attached to the divided extremities of the femoral artery and vein, which allowed the blood to flow through them. When the poison of upas was applied to the severed limb, it produced its effects as under ordinary circumstances ; and as all communication of nerve was cut oflP, it could only be by venous absorption that these effects could be produced. Dr Stevens fidly adopts the views of jNIagendie, as regards the action of poisons by medium of the blood. When a small quantity of the poison of the rattlesnake is inserted into a recent wound or injected into a vein, it causes death in a few minutes ; whereas large quantities of the same poison, administered to animals In* the stomach, produced no effect whatever. What arc we to think of the following instance of toxicological heroism ? Mr Wallace of Virginia took the whole of the poison 330 APPENDIX. from the two fangs of a large and vigorous rattlesnake. This he made into pills, — hags, venom, and all. These he swallowed himself, sometimes at the rate of four a day. " They produced," he says, " most heavenly sensations, and melancholy was quickly changed into gay anticipations ; but, imfortunately, these delightful feelings were followed by a general dropsy, which continued for a considerable period." We may surely say of this experiment, that " The love of science could no farther go." Mr Wallace, however, was perhaps aware of what Liebig has since proved, that animal poisons, intro- duced into the stomach, are decomposed by the gastric juice. Some of the vegetable poisons act almost as speedily, when introduced in this way into the system, as when inserted into wounds. The physiologist, Miiller, inclines to the opinion that it is through the circulation that poisons act upon the system. He nevertheless admits, and that from experimental inquiry, that poison applied to an indi- vidual nerve produces more effect than when applied by means of the blood ; and that it does not always act by absorption, is proved from the circumstance of the iris of one eye being alone affected when bella- donna is applied to the parts externally, as when a solution of the extract is dropped into the eye. " In this instance the poison reaches the ms and the ciliary nerves by imbibition. It is evidently a local effect, and not in the slightest degree the result of absorption into the blood, for the pupil of the other eye is un- affected." POISONS. 331 " The effects of the poison of lead in producing paralysis of the hands are also well known."* The residt of Dr Addison and Mr Morgan's ex- periments led them to the conclusion — " That all poisonous agents produce their specific effects upon the brain and general system through the sentient extremities of nerves, and through the sen- tient extremities of nerves only ; and that, when introduced into the current of the circulation in any way, their effects result from the impression made upon the sensible structure of the blood-vessels, and not from their direct application to the brain itself." — P. 60. " Even where the poisons may be absorbed into the blood, it does not invalidate this conclusion ; for, under such circumstances, they affect the system at large, not by then- being carried to the brain by the blood, but by their du'cct operation upon the internal membrane of the blood-vessels into which they enter, and through which they are carried."— P. 68. A difficulty in the theory of venous absorption, is the minuteness of the dose which pi'oduccs the effect, provided that dose l^e mixed with the large quantity of blood, which it must be, in passing from a vein of the foot to the heart ; the circumstance of the same blood ccoino; throu2;h the luno-g sufferino; decarboniza- tion, and then rcturaing into the heart and being propelled by the carotids to the brain ; all of which must take place before the nerves feel it. The following experiment seems as conclusive in favour of the assertion of Dr Addison and Mr Morgan, * MuUer. 332 APPENDIX. as does that of Magendie in opposition to their views, viz. " All poisons, and perhaps all agents, influence the brain and general system through an impression made upon the sentient extremities of the nerves, and not by absorption and direct application to the brain." —P. 90. " Two dogs, weighing about forty pounds, were selected for experiment. The carotid of each dog having been Uiid bare on one side, and separated from its connexions with surrounding parts to the extent of three inches, temporary ligatures were applied above and below, and the arteries were divided between them. Brass tubes were then attached to the extre- mities of the vessels, and the necks of the two animals being held, and closely bound together, the divided arteries were, without the least difficulty, reconnected, and the circulation renewed. One of the dogs was then inoculated on the back with a concentrated preparation of strychnine, which had been found upon other occasions to produce death in these animals, in about three minutes and a half. In three minutes and a half the inoculated animal exhibited the usual tetanic symptoms which result from the action of this poison, and died in a little less than four minutes afterwards, viz. about seven minutes from the time at which the poison was inserted, during the whole of which time, a free and mutual inter- change of blood betw^een the two, was clearly indi- cated by the strong pulsation of the denuded vessels throughout their whole course. The arteries were next secured by ligature, and c'le POISONS. 333 living was separated from the dead animal, but neither dm'ing the ojDeration, nor at any subsequent period, did the survivor show the slightest symptom of the action of the poison upon the system. — P. 90. In reference to Magendie's experiment, the authors observe : — " Now, whether or not the poison does ever circulate with the blood through the brain, is a question which we do not think it worth while to dispute. We contend that such is not the cause of its operation upon the system ; and whether or not a poison does in all cases enter the circulation, is not the point at issue ; for we have contended that if they do find their way into the veins, they aifect the brain and general system by their direct operation upon the nerves of the inner coat of the blood vessel, and from that cause only." — P. 79. If found to be correct, the principle for which we contend, will not be limited to the operation of those noxious agents usually denominated poisons, but it may probably tend to the better understanding both of the causes and cure of diseases in general. This will justify the conclusion, that the cause of ma- lignant fevers is attributable to the impression which the noxious effluvia makes upon the sentient extremities of the nerves, and that by this means the system is affected. The circumstance of the porters during the plague in JSIarseilles, dropping down upon merely touching the infected bales, has not been overlooked by the authors, nor the circumstance of local injury. " A slight lacerated wound, a biu'n, a puncture from a spicula of wood, or a rusty nail, seem to create little local disturbance at the time, when suddenly 334 APPENDIX. symptoms of tetanus supervene and proceed, to tbe destruction of life." I knew an old gentleman who died of tetanus from the effects of the thorn of a gooseberry bush run under the finscer nail. RUPTURE OF GALL BLADDER. In the winter of 1825 I was suddenly called in the night to Count , and found him suffering from severe pain in the stomach, accompanied by a good deal of flatulency ; and finding, upon inquiry, that he had eaten of lobster for supper, I naturally attributed the attack to indigestion. The usual treatment was adopted, which relieved the symptoms, but as there were considerable uneasiness and fever the following day, he was bled from the arm, which was followed by perfect convalescence. This was the first indisposi- tion from which he had suffered during two years that I had been in his family. He was very corpulent and a hon vivant. He told me, however, that this was not the first time that he had been so attacked, and that he was subject to spasms caused by indigestion. The following year he had a similar attack Avhen at Moscow, where he was treated by an English physi- cian, and again bled. In 1827 he was riding in Hyde Park, and was suddenly seized with violent pain at the pit of his stomach, and fell from his horse. The prac- titioner who treated him upon this occasion, again ordered him to be bled, and enjoined more abstemious living for the future. RUPTURE OF GALL BLADDER. 335 In passing through Dieppe, where I was residing with his family, he gave me an account of his illness, and I begged him to follow the advice given him in London as regarded his diet. lie had not been a month in Paris before I received a letter from his secretary informing me that he was again ill in the same way. He had returned late from a ball, and as he was getting into bed was suddenly seized with the same symptoms as on the three former occa- sions. I immediately went to Paris, and found that he had been in the first instance treated by laudanum and a?ther for indigestion, and had been subsequently bled and freely evacuated. From this time till 1831, a period of four years, I am not aware that he had any return of his disorder, certainly not as far as I was concerned in the treatment. It was in the summer of 1831, just as the cholera made its first appearance, that I was summoned to see him. The Count had joined a party of the Russian nobility, and retreated to an island in the suburbs of St Petersburg, in the view of avoiding all con- nexion Avith those Avho might be exposed to the con- tagion of cholera. He informed me that he had ex- perienced a slight sensation of his old complaint, but that he had taken a dose of physic, and thought it would pass off. He complained of a sense of warmth in the region of the stomach, but of no acute pain ; and ascribed his attack to having transgressed by eating of cold sterlet soup for breakfast. As I Avas occupied in making arrangements with the police regarding the cholera establishments, I left liim, but returned again in the evening. He com- 336 APPENDIX. plained of no uneasy sensation, but was feverish, and his pulse was full, and as he requested me to bleed him, I complied with his request. He was immediately relieved and slept well aU night, and the following day was quite convalescent, and rode out in his carriage. He took leave of me, and jestingly saying he had had his cholera, wished me well through my difficulties, as he knew that I had been appointed to a large temporary hospital, and said he should not see me again till the cholera was over. I heard no more of the Count for nine days, when I met one of his servants in the street, who told me that his master was dangerously ill ; and in spite of the injunctions to the contrary I hastened to him. He was glad to see me, but shrunk back as I approached his bed, for he was afraid of contagion. His medical attendant, an Italian, told me that since I had last seen him he had been attacked with inflammation of the liver, that he had been bled three times from the arm, and taken forty-five grains of calomel. I had hardly time to gather these particulars, Avhen the friends who were about him begged me for God's sake to leave the house, for I had violated the quarantine, and had probably introduced the cholera among them. They requested me not to return, and strict orders were given to admit no one who came from the city. I heard no more of the Count's state till the 30th, when I was summoned in the night, with five other physicians, as he was considered in great danger. A biliary calculus had been found in the stool of a pear shape, measuring more than an inch in lengthy and about six lines in its broadest diameter. Previous PUNCTURE OF THE INTESTINES. 33-7 to passing this, there had been a good deal of fever and local irritation, wliich were not relieved by the voiding of the gall stone. The mercury had produced salivation, and the parotid on one side was very much enlarged. The patient could not articulate clearly ; the pulse was quick, small, and intermitting, and he expired forty- eight hours after passing the calculus. It was almost impossible to get a sectio cadaveris, owing to the general state of alarm produced by the cholera, and the public disturbances at the time. I insisted upon it, however, for I had suggested that the gall bladder had been ruptured, and I succeeded in ascertaining this to be the case. The gall bladder was hardly to be traced ; a large abscess was found immediately beneath it, and the whole of the fundus of the former was ulcei'ated away. The case is instructive, as far as the evidence is in favour of the frequent occurrence of the spasms of the stomach having been owing to passage of gaU stones, or from the introduction of this identical one into the duct, from which it again receded. — From the Medical Gazette, vol. xiii. p. 711. PUNCTURE OF THE INTESTINES. To relieve the agony of distention in two cases of siip- posed internal strangulation. The lady of an officer of high rank, had been suifer- ing for some time Avith disordered digestion, when she was suddenly seized with violent vomiting and purg- ing, and f;ecal matter was discharged by the mouth. Q 338 APPENDIX. To this succeeded constipation and tympanites — the latter being so distressing that it was resolved to punc- ture the bowels. Large quantites of gas escaped — the patient felt immediately relieved from her extreme sufferings. She died the same day or the following. I did not see this case myself; but as it was attended by the same medical men, who were present in the second, and no great interval occurring between the two, it was reported to me as above. A lady, the mother of six children, was in the family way with the seventh, and in about the fourth or fifth month of utero gestation. She had for years been in the habit of neglecting her bowels, and retaining her faeces for five and six days, and even longer, with im- punity. She complained of sudden pain in the bowels, which she took to be colicky, and used some domestic medicine. The pains increasing, and the bowels con- tinuing locked, blood was taken from the arm, and leeches applied very freely to the part. No relief was afforded. The abdomen became very tense, and the pains returned at repeated intervals. She expressed herself thus, that she had borne six children, and that the united pains of all her labours, M^ere not so excru- ciating as any one of the pains under which she suffered. All means had failed in procuring her relief. Six or seven medical men were in constant attendance upon her. Injections, Avami baths, cold affusions, bleeding, opium in large doses — nothing relieved her. It was, therefore, upon the idea only of shortening her sufferings, that it was proposed to puncture the intestines. A trocar was thrust into the colon — some PU^XTUEE OF THE INTESTINES. 339 gas escaped, and she exclaimed I can breathe now — faeces soon filled up the canula — the spasms retm-ned, but in rather diminished force. She sank in about fourteen hours after the operation, suflfering to the last. In neither of these two cases, was ?i j)ost mortem examination allowed.* It becomes a question of moral import, in how far such an operation can be held justifiable. It must first be taken into consideration, what would be the chances of the result of such an operation in a state of health. Would not a pointed instrument of the size of a trocar, be, in all probabilities, attended with fatal consequences. If so, in a state of disease, the chances of the patient's recovery from the ope- ration would be diminished by the previous state in which the parts were, owing to the obstructing cause. In the second place — is the temporary relief so aflforded, made justifiable in the operation, seeing that cases of internal strangulation do sometimes recover, and that the bowels get unlocked in what is looked upon as the agony of death, but which proves to be the jaiina viUf. As there is an eleventh hour in all matters, is it not more justifiable to await its sound- ing, than to make its fatal voice doubly sure. I am not sure whether such an operation has been performed in England under such circumstances, and for such express purpose only. I was present in the latter instance, and did object to the o})eration, finding that it had been fatal in a similar case, not long before. I almost question whether it would not have been * St Petorsbiirg, 1842. 340 APPENDIX. suggested to do the like in the folloAving case, wliich occurred to me since my return home, where nature relieved herself at the eleventh hour. The case was read before the JSIedico Chinu'^ical Societv. Coses of Ohstruction in tlie Intestinal Canal, terminat- ing favourahly on the ninth day hy Spontaneous Vomiting. The subject of the present case was a little girl of twelve years of age, of a very delicate constitution, strongly marked scrofulous disposition, and with very feeble digestive powers, so that she was imable to digest fruit or vegetables. She had been attacked by epidemic autumnal cholera, which prevailed amongst children in the town where she was residing, and which yielded to the usual mode of treatment. Soon after the termination of this she was attacked by a disease of an opposite nature, and became obstinately constipated, whilst tlie stomach rejected every thing that was taken. Purgatives had been employed in every shape, but without effect ; leeches had been applied to the abdomen, which had been fomented freely. Such was the history of the case which I received from the two medical men in attendance, previous to my seeing her on the 27th of August, in the afternoon. She was much flushed in the face, had an anxious countenance, a small, quick, compressible pulse, a cold, moist surface, the extremities being colder than natural. She suffered from distention of the abdomen, without complaining of much pain, and PUNCTURE OF THE INTESTINES. 341 she vomited continually a green bilious fluid. As no inflammation was apparent, and as more depletion was not, under the existing circumstances, indicated, soothing measures were employed. The vomiting was the most annoying symptom, from its frequency rather than from any distress which it occasioned, for this dark-green fluid Avas thrown up without much efi^brt. A small blister was applied to the pit of the stomach, and small doses of prussic acid administered in almond milk. This treatment seemed to check the vomiting for many hours successively. She passed a tranquil night, but no relief to the bowels had been obtained by stool, and the abdomen Avas much more swollen. Croton oil was given internally and by clyster during the day, and as w^arm applications seemed to have no eflTect, bladders filled with ice were applied over the belly. The patient was restless and uneasy, continually changing her place in bed, but this arose from distention rather than from any acute pain. About midnight of the 28t]i, she complained of twist- ing and severe pain in the bowels of a colicky nature, there was also more pain upon pressure than pre- viously, and, as opiates were administered without benefit, I applied a dozen leeches to the abdomen, with immediate relief to the distressing symptoms, Avhich subsided soon afterwards. She got some sleep, and was free from pain wh«n awake. I was obliged to return to London, and did not see her again till the afternoon of the following day. I learned from the physician in attendance, that she had passed the day on which I left licr, pretty well, but that, at midnight, the same symptoms recurred as on the night previous, 342 APPENDIX. and, notwithstanding her great state of exhaustion, he had again applied leeches with benefit. He in- formed me that the vomiting had returned, and that the matter brought up was evidently from the ileum, and the seat of stricture seemed to be about the caput CfBci. There was no question, upon minute examina- tion, that the matter vomited up proceeded from the small bow^els. The distention was now very great, respii'ation was much impeded, and the little patient suffered severely. A long elastic tube was introduced into the rectum, and cari'ied up into the colon, through which water was forced by a pumping-syringe. The operation was productive of great distress to the patient, and was ineffectual as to relief. The night was restless, and the following day the little sufferer was much exhausted. The face was colourless, the countenance anxious, the body covered with a cold clammy sweat, and she expressed herself as if about to die. The bed-room having a southern aspect, and the weatlier being sultry, I desired that she might be removed into a cooler room. She was carried in the arras to her bed, and, as she was much fatigued by the operation, I gave her a glass of Madeira wine, which she drank Avith pleasure, but hardly had she swallowed it when she made signs for the basin, lifted herself up in bed, and threw up a dark green fluid to the amount of three pints. She experienced immediate relief, and breathed more freely, and the upper part of the body became more loose and compressible. I gave her some more wine, which remained on her stomach ; she had no more nausea. Constant friction was maintained over the abdomen, and injections of MESMERISM. 343 vinegar and water were repeated every hour. The first was returned without being accompanied by any solid matter, but had a foetid smell. The second Avas accompanied by pieces of flocculent matter, of a membranous appearance, and the fluid returned was horribly foetid, like putrid Avater in which flesh had been macerated. She Avas enabled to compress the abdominal muscles and make an effort to go to stool, Avhich the previous great distention, paralysing the action of the muscles, had prevented her from doing. Much of this membranous matter came away after each injection. The smell was most offensive. About four hours after the spontaneous vomiting she asked to go to the chair, Avhen the bowels gave Avay, and a large quantity of solid excrement Avas voided. She passed more stools in the course of the evening, and then slept tranquilly. The following morning I gave her a dose of castor oil, Avhich produced its desired effect without creating nausea, and I left her conva- lescent. I learned, subsequently, from my colleagues, that she had a good deal of constitutional fever for four or five days. She recovered in a short time, and her digestive powers are now better than previous to her illness. The obstruction Avas relieved only on the ninth day of the disease. MESMERISM. " A second critical remark Avhich suggests itself in connexion with this subject, relates to the opinion that by virtue of the exaltation or transposition of sensi-^ 344 APPENDIX. bility, it is possible for persons to see Avitli the skin. It is a known fact that we cannot by means of the fingers recognise coloiu's as such, although it may be possible to distinguish the corpus or grain of some colouring matters when laid thickly upon a surface, since they are uneven, and adhere to the skin which touches them. " The necessity for an optical apparatus for the pro- duction of an image upon a percipient membrane, suf- ficiently refutes the notion of persons being able to see with their epigastrium, or with the fingers, when in the so named magnetic or mesmeric states. Even though the skin of the epigastrium or fingers were susceptible of the sensation of light, which they are not, the perception of objects would yet be impossible, unless there were optical apparatus for collecting the light radiated from certain points of the object upon corresponding points of the sensitive surfiice, and without such apparatus, the epigastrium and fingers, though they possessed the sensibility of light, would merely be able to distinguish light from darkness. Since, however, these parts are not susceptible of the sensation of light, and since no sense can be transferred from one part to another, it is quite impossible for a person in the magnetic state to have even an obscure perception of light and dark- ness by means of any other parts than the eyes. Moreover, when the eyes are bound it is still possible to distinguish the light and even objects, by slightly raising the eyelids, as every one well knows who has played at the game of blind man's buiF, and persons lying, like the subjects of the pretended magnetic sleep, in the horizontal posture, with the eyes bound, can see MESMEKISM. 345 every part of the room by looking under the bandage. But what well informed physician can put faith in the fables told by the upholders of animal magnetism. It is quite in accordance with the laws of science that a person sleeping shall have ocular spectra ; we ex- perience them sometimes when the eyes are closed even before falling asleep, for the nerves of vision may be excited to sensation by internal as well as by ex- ternal causes ; and so long as a magnetic patient manifests merely the ordinary phenomena of nervous action that are seen in other disorders of the nervous system, it is all credible enough. But when such a person pretends to see through a bandage placed before the eyes, or by means of the fingers or the epigastrium, or to see round a corner, and into a neighbouring house, orto become prophetic, such arrant imposture no longer deserves forbearance, and an open and sound exposure of the deception is called for." — Alilllers Physiology, p. 1125, vol. ii. In the neighbourhood of Musselburgh was a chapel dedicated to our Lady of Loretto, the sanctity of which was increased from its having been the favourite aljode of the celebrated Thomas the Hermit. To this sacred place the inhabitants of Scotland from time im- memorial had repaired in pilgrimage to present their offerings to the virgin, and to experience the virtue of licr prayers, and the healing power of the wonder working " Hermit of Lareit." In the course of the year 1559, public notice was given by the friars, that they intended to put the truth of tlieir religion to the proof, by performing a miracle at the cliapel of Loretto upon a young man who had 346 APPENDIX. been bom blind. On the day appointed a vast con- course of people assembled from the three Lothians, The young man, accompanied by a solemn procession of monks, was conducted to a scaffold erected on the outside of the chapel, and was exhibited to the mul- titude. Many of them knew him to be the blind man whom they had often seen begging, and whose neces- sities they had relieved, — all looked upon him and pro- nounced him stone blind. The friars then proceeded to their devotions with great fervency, invoking the assistance of the Virgin, at whose shrine they stood, and of all the saints whom they honoured ; and after some time spent in prayers and religious ceremonies, the blind man opened Jm eyes to the astonishment of the spectators. Having returned thanks to the friars and their saintly patrons for this wonderfid cure, he was allowed to go down from the scaffold to gratify the curiosity of the people, and to receive their alms. It happened that there was among the crowd a gentleman of Fife, Robert Colville of Cleish, who, from his romantic bravery, was usually called Squire Meldrum, in allusion to a person of that name who had been celebrated by Sir David Lindsay. He was of protestant principles, but his wife was a Roman Catholic ; and, being pregnant at this time, had sent a servant with a present to the chapel of Loretto to procure the assistance of the Virgin in her approaching labour. The squire was too gallant to hurt his lady's feelings by prohibiting the present from being sent off, but he resolved to prevent the superstitious offering, and with that view had come to Musselburgh. He had witnessed the miracle of curing the blind man MESMERISM. 347 ■with the distrust natural to a protestant, and he de- termined, if possible, to detect the imposition before he left the place. Wherefore, having sought out the young man from the crowd, he put a piece of money of considerable value into his hand, and persuaded him to accompany him to his lodgings in Edinburgh. Taking him along -uith him into a private room, and locking the door, he told him plainly that he Avas convinced he had engaged in a wicked conspiracy with the friars to impose upon the credulity of the people, and at last drew from him the secret of the story. When a boy, he had been employed to tend the cattle belonging to the nuns of Scienncs, in the vicinity of Edinburgh, and had attracted their attention by a peculiar faculty of turning up the whites of his eyes, and of keeping them in this position, so as to appear quite blind. This being reported to some of the fi-iars in the city, they immediately conceived the design of making him subservient to their purposes ; and having prevailed on the sisters of Sciennes to part with the poor boy, they lodged him in one of their cells. By daily practising he became an adept in the act of counter- feiting blindness ; and after he had remained so long in concealment as not to be recognized by his former acquaintances, he was sent forth to beg as a blind pauper, the friars having previously bound him by a solemn vow not to reveal the secret. To confirm his narrative, " he played his pavie before Clcish by flyp- ing up the lid of his eyes, and casting up the white, so as to appear as blind as he did on the scaffold at Loretto." — M'-Crie's Life of John Knox, p. 324, vol. i. 348 APPENDIX. PLICA POLONICA. It is singular that, in the present advanced state of medical science, any doubts should exist respecting the nature of a disease which, from its circumscribed influence, has received the name of plica polonica ; still, even at the present moment, the medical opinion is divided upon the reality of its existence as a specific complaint. This discordancy of opinion is not con- fined to strangers, or to those medical men who, not having sojourned long in the country where the disease is endemic, have had but little opportunity of investi- gating the matter, but the medical men resident in those parts where it is most prevalent, do not seem, as far as I could ascertain it, to have made up their minds upon the subject. There are three opinions, however, which may be quoted regarding the nature of this affection. The first, and a very general one, that the said plica is nothing more or less than an aggregation of filth. The second, a very limited one, that it is a specific contagious disease, produced by a peculiar virus. The third, and the more probable one, that it is a secondary affection, or a critical excretion from the scalp and roots of the hair, and the natural curative process of a variety of complaints. Several reasons may be assigned for the discrepancy of opinions which exist upon this subject, and which place it among real or artificial diseases. It is in general confined to the lowest orders of society. Such excite little interest or compassion ; and their modes PLICA POLONICA. 349 of life, which place them, as regards cleanliness, even below many of the brute creation, have acted as an insuperable barrier to the thorough investigation of this disease upon those spots where it is endemic. When it attacks, on the contrary, the better classes of society, it is studiously concealed from the world in general, and often from the medical attendant ; unless, having resisted all nostrums, it becomes too aggravated in its character to be trifled with any longer. The same cause has operated in both cases to pre- vent sufficient attention having been paid to it in all its stages. The peasant is too filthy to be attended to; the rich man is too proud to allow himself to be suspected of labouring under the curse of that which is the fitter property of his boor. Hence it is that so little real information is to be gained from the number of authors who have written upon this subject. Each has contented himself with re-stating or criticising some preceding opinion upon the disease ; few have taken the trouble to investigate the truth by observ- ing simply with their own eyes what lay in their daily path. So we are told of the errors into which Her- cules de Saxon ia fell, from his too great belief in supernatural agents. Davidson, on the other hand, is reprobated for his scepticism ; Schlegel is too diffuse ; Gasc too concise in his description ; but the authors of these criticisms do not think of telling us what they saw themselves. To unfold a plain unvarnished tale, must be left, I believe, to the Ghost of Hamlet ; for no one Uvino- eeems disposed t(j do it. Wc find that not only the 350 4.rPENDix. real existence of the disease is a matter of contention, but its origin and progress are equally twisted, like itself, from the path of truth, by those who believe in its existence. Its name and numerous synonyms indicate a great difference of opinion as to its origin and effects. First, as to the opinion of many, that it is only an affo;reo;ation of filth. I have, myself, known it occur in five opulent fami- lies, where any question of uncleanliness could not for a moment be agitated ; and this is itself sufficient to disprove the validity of this sweeping clause. Having, previously to my visiting Poland, read several works upon the subject, and found them abounding in controversy and confusion, I was in hopes that during my residence in the ancient capital of the Piasts, I might gain some clearer evidence upon the matter. Being convinced, from what I have already stated, that uncleanliness alone could not account for all that I found to exist, it became, nevertheless, ne- cessary to ascertain how far this operated as a cause, knowing that cause and effect are often so blended together, that it is difficult to separate them. Here arose a stumbling block at the threshold of inquiry ; and it was necessary to refer to popular pre- judices, not as a standard of truth, but as a standard of error, from which truth may often be elicited. I found that there was but one opinion held by the people regarding the effects of the disease, how diverse soever their opinions might be as regarded its causes. All agree that the effects of the plica are most salu- tary to the system ; and there are few earthly blessings PLICA POLONICA. 351 which are more coveted by the peasant than the for- mation of a plica in his hair. Two circmnstances meriting attention are to be considered, as arising from this opinion — the one, that relief is afforded to the system under certain morbid states by the for- mation of a plica ; the other, as a necessary conse- quence, that means will be devised to promote its formation. From these two circumstances arise also a very important subject for consideration, viz., that the methods frequently resorted to, in order to promote this effect, have tended to establish the opinion, that the disease is at all times an artificial production. It is said to be good for the ague, for the gout, for sore eyes, for obstinate headaches ; and females find it good for a variety of complaints ; consequently, as soon as they are afflicted with any of these grievances, they immediately commence forming an artificial plica. Of this I have positive proof in the following in- stance : — I was requested to see the daughter of a person in very easy circumstances, who was affected with sore eyes, and had a defect in her vision. She was about fourteen years old, and was, when I first saw her, lying upon the bed : her hair was twisted and matted together, and the animals in such quantities that I could not approach her without feeling disgust. She had a speck upon one cornea, and seemed to be suf- fering from rheumatic ophthalmia. Upon inquiring why she was confined to her bed, and if she had the plica, her motlicr replied not as yet, but slie was in hopes that it would not be long in coming ; for which purpose her daughter was kept as warm as possible. 352 APPENDIX. " For the same reason, I suppose, you do not allow her to comb her hau', or keep her head clean ?" " Yes," was the reply. " And what do you expect will be the consequence ?" " A plica will form in her hair, and cure all her complaints." " AVill her eyes get well as soon as the plica is formed ?" I inquired. " No, not immediately ; but as the head gets worse, the eyes will, by degrees, get better, and when once cured, she will never be subject to have sore eyes again." " How long will this plica last ?" I inquired. " About three rears," was the reply. " And what then ?" '• The old hair will die away, new hair will shoot out from the scalp, and then we shall cut away the old by degrees, and she will have a fresh head of hair." All this information Avas founded upon the expe- rience of the mother, whose son had suffered some years previously, in the same way, and was cured by the same means. Some days later, I visited the public hospital. In passing by one of the beds, I observed an old woman, whose head appeared enveloped in the remains of a flannel petticoat. I inquired what ailed her. The interpreter replied, Koltun, the name given to the disease by the people. I was anxious to examine it myself; the attendant replied, that it was not as yet fully formed, that she was encouraging it all in her power, and so wrapped up her head in flannel. I inquired why she was so anxious to produce a plica. " The old woman is a martyr to rheumatism, and this is an infallible cure for it — the universal remedy," said the young surgeon who interpreted for me. In the meantime, she had taken the wrappings oft' her PLICA POLONICA. 353 head, and I found the hair all twisted together, and very lively, as I had observed it in the other patient. The plica was much farther advanced in this latter case. The mass of hair upon the crown of the head resembled a dirty bird's-nest : but upon examining the hau's individually, I could perceive no alteration in their structure. Such a plica might evidently be pro- duced at any time, and as easily in Cork as in Cracow. The old woman was much displeased at being obliged to undo her flannel wrapper, from fear of the exposure to the air retarding the progress of the disease. These two cases sufficiently prove that means are resorted to in order to produce an agglutination and conglometion of the hair, for the purpose of relieving the system of some painful affection ; and this forms the false or artifical plica. This is considered by many as the only disease ; and when so many cases can be traced to this, and this alone, it is not singular that with many, farther investigation is not considered necessary. The following case, which occurred to a servant girl in the family of Dr Typaldoes, an amiable Greek physician, then residing in Cracow, illustrates the relief afforded to the system by the spontaneous ap- pearance of a pHca, when no artificial means had previously been used to produce it. She had been afflicted for several months with violent pains in the licad, which resisted all medical treatment. As the winter approached, the headaches got Avorse and worse, and dui-ing the night were quite insupportable. In the month of January, the thermometer being 22° Kcaumur, she left her l)ed, and went down stairs to 354 APPENDIX. get ice to put upon her head. She caught a severe cold by this imprudence, and a fever, with delirium, was the result. The usual means were employed to combat the fever and head affection, but nothing succeeded, till suddenly a plica formed itself upon the scalp, and she gradually got better as the plica in- creased. In such a case, the old term, vis medicatrix naturo', seems to estabHsh a claim upon our attention. It is natural to ask if the pliea formed in this spon- taneous Avay, differed in appearance from those which I have described, and which were artificial productions. I cannot reply to this from my own ocular evidence, but Dr Typaldoes informed me that it was a true l)lica, for that the structure of the hairs was altered ; but the patient immediately resorted to the same artificial means of promoting its increase as the others had done to favour its production in their cases ; so that even in this case it soon became impossible to distinguish truth from falsehood. I shall explain what is considered to be the differ- ence between the real and false plica, as briefly as possible ; but I shall first mention a few circumstances, which may puzzle many who uselessly devote their time to read all the difierent authors who have written upon this malady. First, as to the various names given to it by different writers. A good deal is to be learnt from this variety of appellations, most of which express some supposed or real character in the complaint itself ; and first, of the popular name of Koltun, which signifies a stake, be- PLICA POLONICA. 355 cause the hair stands out like a pole or stake. This implies no matting of the hair, as a Medusa's head ; no interlacing of the hairs in meshes ; but a thickening of the hair, either from conjunction of several hairs in a strait direction, or from a thickening of individual liairs ; and many have drawn a distinction between the true and false plica, from the disposition of the hairs alone. When it affects other parts of the body than the head, this is the form which it is said always to assume ; and we read of cases where it has increased to such a length as to pass three times round the thigh. The vulgar name Koltiin is not to be disre- garded in the investigation of the nature of this dis- ease. The following name I shall quote as offering one of the many difficulties which occur in the study of the malady. Plica judaica, Judenzopf, are commonly met with in writers, and yet I was informed by my colleagues, in Cracow, that the plica was rarely to be met with among the tribes of Israel. If such be the case, it affords negative evidence, at least, to the opinion that this malady is engendered by filth alone ; for if there is a mass of living filth in human shape, it is to be I'ound in a Polish Jew, who stalks up and down the streets in a long gown, and fur cap upon his head, nor changes his gabardine till it falls piecemeal off his body, rotted by age. His long flowing hair falling in ringlets upon his shoulders, and curling at the ex- tremity, would seem to offer a fine nursery for plica ; still, as I was informed, he is seldom attacked by this 35G APPENDIX. disease, but enjoys, as a substitute, more generally diffused over his body, the psoriasis. It Avas not asserted that no cases were to be found among the Jews, but that there were but few, comparatively with the peasants. I recollect seeing but one Jew affected with plica, during the time I remained at Cracow. Another name, and one indicative of its locality, is Weichselzopf ; because it is found to prevail especially on the banks of the Vistula ; and the popular tradition runs, that when the Tartar hordes came over the Car- pathian mountains, and invaded Poland, they poisoned the sources of this river. In the name of Mahrenflechten is expressed, that the Moravians, when enemies to Poland, had recourse to magic to conquer them, and gave them this unseemly complaint. So witchcraft is likewise expressed in the term Hexenzopf. Thus much for nomenclature ; and as to locality, I can only state what I have myself observed. This is, again, a much disputed point ; some asserting that it is confined entirely to Poland, others that it is to be found sporadically scattered over Hungary and many parts of the north of Germany. i\Ir Eussell says " it is found in Livonia and some other parts of Russia, and, above all, in Tartary." I found it prevalent in the republic of Cracow, in the Kingdom of Poland, and in the whole province of Gallicia, along the banks of the Vistula. In quitting this river, I lost sight of the disease, nor did I find any traces of it during some weeks' sojourn in the Ukraine and in the province of Podolia, as far down as Odessa. PLICA POLONICA. 357 I have never seen a single case in Russia Proper, nor even in Finland ; which all coincides with what others have Avritten upon the subject. Such evidence must go far to prove that filth cannot be the only source of this complaint. Some stray cases may occur in other countries bordering on Poland, but in none that I have mentioned is it a disease of the country. Another pomt of controversy is with respect to the disease attacking strangers. Some assert that strangers are not susceptible of it ; others, that they only become so when they adopt the costume of the country : both these opinions are erroneous. An instance of the contrary occurred in the family in which I was residing. A lady's maid, who came from Berlin, to attend the Countess , was very seriously attacked with this complaint; it commenced by headaches and general rheumatic pains, and finally terminated in plica. Now tliis young woman, from the middle class of society, had not been more than six months in the family, and had adopted no national costume. I know not what may have been the dress of a lady's maid in the time of the Casimirs, but at present, I believe, it is the same over Europe in general. Neither, therefore, are strangers free from it, nor is it produced by dress alone. Some have stated that the disease is contagious ; but this opinion is combated by one of the earliest writers, — viz. Hercules de Saxonia, who published in 1()(J0, and from whose ))Ook much is to be learnt. He is quite furious at the idea, and instances, in incon- trovertible evidence to the contrarv, that a learned 358 APPENDIX. professor, of his acquaintance, was afflicted with it to grievous extent, but his barber, who shaved him and dressed his plica, did not catch the disease. This author does not beheve that the plica is ever epidemic, although he has great faith in sol-lunar influence and the aspects of the heavens upon complaints in general. As to its endemic character, he can point out the spots where it is to be found at all seasons of the year. Mr Russell has fallen into error upon this subject. He says that " it is contagious, and moreover may become hereditary. In Cracow there is a family, the father of which had the Weichselzopf, but seemed to be thoroughly cured of it ; he married shortly afterwards, and his wife Avas speedily subjected to the same dis- order, and of the three children she bore to him, every one inherited the disease." Had the author stated that the complaints which engendered plica are hereditary, he would have been nearer the mark ; but neither cause nor effect, in this case, can be considered contagious. With respect to its affecting the brute creation, the opinion is generally in favour of this idea. Pigs and horses are particularly subject to it, Schlegel is of opinion that it is so prevalent among horses, that one out of six is attacked by it, both in Moscow and Peters- burg ; a privilege which the cattle enjoy over the people in these capitals. Six years' residence in the latter city, and a considerable acquaintance with horse flesh, have not yet introduced to me the disease in that animal. In travelling from Cracow to Leopold, I observed that the manes of the peasants' horses had a peculiar EXPERIMENTS ON ANIMALS. 359 appearance, and that the pigs were much in the same predicament. The postihons informed me that it was the koltiot. Upon close examination, however, I could not convince myself but that a comb would unravel it, if regularly applied. It is too much, how- ever, to expect that a man should comb his horse who never as yet combed himself. I shall not dilate more upon the controversies which are to be found in the different works upon this sub- ject ; many of the writers are not only at variance with their colleagues, but even with themselves. Few describe what they have themselves seen, or the results of their own study and observation. From what has been said, I think it will be evident that the two first opinions — viz. that the plica is nothing but an aggre- gation of filth ; and, secondly, that it is a contagious disease, depending upon a peculiar virus — are neither of them tenable. The third, or that which allows of its existence, as a critical termination of other com- plaints, is alone worthy of attention. We do not say, liowever, that in no instance the hairs may not be affected primarily, but that the disease is not capable of being propagated by contagion, or that the virus can be communicated by inoculation, as many have contended. EXPERIMENTS OX ANIMALS. "\Vc do most cordially sympathize with Dr EUiotson in the anathema which he pronounces against the repetition of cruel experiments to prove what is already 360 APPENDIX. known and established. It is most true also, as he observes, that the proofs afforded by such are of a most doubtful character, from the effects of pain which they produce, changing the whole economy of the animal. If the mere prick of a pin shall throw a man into a swoon, which suspends every function of the system, so that the eye sees not, nor the ear hears, nor the blood flows, is this a state in which we are to look for the performance of a function, or draw conclusions which shall amount to proof ? Artificial mutilation is not calculated to afford much information. We know^ not how much farther the Americans may have pro- gressed in their experiments upon the human subject. We once saw an advertisement in a Yankee journal, of incurable negroes for sale to make experiments upon. The ancients considered it justifiable to open men alive, but only malefactors. The utility of experiments is not to be doubted in the prosecution of the science of medicine. If human life is to be benefited by the sacrifice of the inferior animals, let it be so, but there are bounds to be set to the practice. The circulation of the blood, and the important consequences derived from this knowledge in surgical operations, — viz. the cure of aneurism, sufficiently justify the principle; and as great good has already been so achieved, so more may be anticipated, but an indiscriminate abuse of animal suffering, under the hands of Tyros, cannot be sufficiently reprobated. To make experiments for experiment sake, and to make them upon some induc- tive principle, with a view to ascertain an important point, are two different things. The one is wanton cruelty, the other a legitimate pursuit of knowledge. SOUND. 361 and in this case the end may justify the means ; but few are capable of prosecuting this subject so as to produce any real benefit to science, and, therefore, it should be intrusted but to few. A wanton sacrifice of animal life is highly censurable. It hardens the heart, blunts the feelings, and has in every respect an im- moral tendency. SOUND.-^ " On the fifth day of my journey, the air above lay dead, and all the whole earth that I could reach with my utmost sight and keenest listening, was still and lifeless, as some dispeopled and forgotten world, that rolls round and round in the heavens, through wasted floods of light. " The sun growing fiercer and fiercer, shone down more mightily on me now than ever he shone before ; and as I drooped my head under his fire, and closed my eyes against the glare that surrounded me, I slowly fell asleep, for how many minutes or moments I can- not tell ; but after a Avhile, I was gently awakened by a peal of church bells — my native bells — the innocent bells of Marlen, that never before set forth their music beyond the Blagyon hills ! My first idea naturally was, that I still remained fast under the power of a (h-eani. I roused myself, and drew aside the silk that covered my eyes, and plunged my bare face into the light. Then, at least, I was well enough awakened ; but still those old Marlen bells rune; on — not ringing: * Sep pa^e 100. 362 APPENDIX. for joy, but properly, prosily, steadily, merrily, ring- ing for ' church.' " After a while, the sound died away slowly ; it happened that neither I nor any of my party had a watch, by which to measure the exact time of its lasting, but it seemed to me that about ten minutes had passed before the bells ceased. I attributed the effect to the great heat of the sun, the perfect dryness of the clear air through which I moved, and the deep stillness of all around me ; it seemed to me that these causes, by occasioning a great tension, and consequent susceptibility, of the hearing organs, had rendered them liable to tingle under the passing touch of some mere memoiy, that must have swept across my brain in a moment of sleep. Since my return to England, it has been told me that like sounds have been heard at sea, and that the sailor becalmed under a vertical sun in the midst of the wide ocean, has listened in trembling- wonder to the chime of his own villao'e bells." — Eotlien, p. 273. The above extract, from a most interesting and original Avork, Eothen, is deficient as regards the circumstance, that the author does not state whether his attendants heard the ringing of the bells as well as himself. It is material to know this before the subject can be discussed upon physical i^rinciples. His own suggestion seems to be the correct one. Some humming noise assailed him before he went wholly to sleep ; and we have stated, that the sense of hearing is the last w^hich falls into slumbering oblivion. jMemory, still on the watch, recalled to him the sounds of his village bells, and then left him under SOUND. 363 tills impression. Upon waking by degrees, the sounds still remained, and the physical and moral feelings were too strong to be overcome by the simple cir- cumstance of the visual organs being fully awake, for seeing is not always believing, in this half waking state. The time is indefinite also. We are no judges of time under such circumstances — a minute may appear an age. Still, even hours and days are some- times not sufficient to wear out the impression of some sounds on the auditory nerve. If others heard it as well as himself, the tactics must be changed. The wonders of the mirage, and the revived theory of undulations may, perhaps, be applicable to sound, as well as to light. Then it may be, that the author heard his village chimes.* * See Dr Brewster's Essays on the Mirage. THE END. MURRAY AND GIBIi, PRINTKRS, GEORGE STREET, EDINBURGH. September, 1844. A CATALOGUE OF NEW WORKS AND NEW EDITIONS PRINTED FOR LONGMAN, BROWN, GREEN, AND LONGMANS, LONDON. ANALYTICAL INDEX. AGRICULTURE AND RURAL AFFAIRS. Pages Kayldon on Valuine: Rents, etc. - - 6 ,, the Varuiitioii of Property for Poor's Rate --.--- 8 frocker's Land Surveying - - - 9 Davy's Agricultural Chemistry - - 9 Greenwood's (Col.) Tree-Lifter - - 12 Hannam On Waste Manures - - • 12 Joliiison's Farmer's Encyclopaedia - - 16 Loudon's Kiicyclopicdia of Agriculture - 19 ,, (Mrs.) Lady's Country Companion 18 Low's Breeds of the Domesticated Animals of Great Britain - - - - 20 ,, Elements of Agriculture - - 20 ,, On Landed Propertv - - - 19 Whitley s Affiicullural Geology - - 32 ARTS, MANUFACTURES, AND ARCHITECTURE. Brande's Dictionary of Science, Litera- ture, and Art 7 Givilt's Encyclopajdiaof Architecture - 12 Loudon's Kucyciop^ediaof Cottage, Farm, and Villa Architecture and Furniture - 18 Porter's Manufacture of Silk - - - 2!> „ ,, Porcelain & Glass 25 neid (Dr.) on Warming and Ventilating 25 Savage's Dictionary of Printing - - 27 Steam Engine (The), by the Artisan Club 28 Urc's [Jictiouary of Arts, Manufactures, and Mines 31 Wathen's Arts, etc. of Ancient Egypt - 31 BIOGRAPHY. Aikin's Life of Addison .... 5 Bell's Lives of the most Eminent British Poets 6 Biographical Dictionary of the Society for the Diffu.ion of Useful Knowledge - 6 Dover's Life of the King of Prussia . . 10 Dunbam'i Lives of the Early Writers of Great Britain - - - 10 ,, Lives of the British Dramatists 10 Foritcr's Statesmen of the Commonwealth of England 11 Gleig's Lives of the most Eminent British Military Commanders .... 11 Grant (Mrs.) Memoir and Correspondence 11 Hunter's Life of Oliver Heywood - . Ifi James's Life of the DUck Prince • - IG BIOGRAPHY. Pages James's Lives of the most Eminent Foreign Statesmen ... - - - Ifi Maunder's Biographical Treasury - - 21 Roscoe's Lives of Eminent British Lawyers 20 Russell's Correspondence of the Duke of Bedford G Shelley's Lives of the most Eminent Lite- rary Men of Italy, Spain, and Portugal 27 ,, Lives of the most Eminent French Writers . - - 27 Smith's Memoirs of the Marquis De Porabal 28 Southev's Lives of the Bridsh .Admirals . 28 Tate's Horatius Restitutus . . - 29 BOOKS OF GENERAL UTILITY. Black's Treatise on Brewing . - - 6 Donovan's Domestic Economy - - 10 Hand-Book of Taste- - - - - 12 Hints on Etiquette 13 Hudson's Parent's Hand-Book - - 15 ,, Executor's Guide • * - 15 „ On Making Wills - . - 15 Lorimer's Letters to a Young Master Mariner ------ 18 Maunder's Treasury of Knowledge - - 22 ,, Scientific and Literary rreasury 22 ,, Treasury of History - - 22 ,, Biographical Treasury - - 22 ,, Universal Class-Book - - 22 Parke's Domestic Duties . - - - 24 Riddle's English-Latin and Latin-English Dictionaries - - . - - - 25 Short Whist . - - - . - 27 Thomson's Domestic Management of the Sick Room ... - - - 30 Tomlins' Law Dictionary - - - - 30 Webster's Ency. of Domestic Economy - 32 BOTANY AND GARDENING Callcotl's Scripture Herbal . . . s Conversations on Botany . . . g Drummond's First Steps to Botany . - 10 Glendiuning On the Culture of the Pine Apple 11 Greenwood's (Col.) Trcc-Liftcr - . 12 llcnslow's Botany 13 Hosre On Cultivation of the Grape Vine on Open Walls 13 ,, On the Management of the Roots of Vines 13 London: Printed by Ma , Ivy.lane,St. Paul', ANALYTICAL INDEX Hooker's British Flora . • - ,1 Icones Plantarum ,, and Taylor's MuscologiaBrita Jacks 's Pictorial Flora - - - - Knapp's Gramiiia Britanaica - - - Liudley's Theory of Horticulture „ Outlines of the First Principles of Horticulture - ,, Guideto theOrchardandKitchen Garden t. Introduction to Botany - „ Flora Medica . - . - ,, Synopsis of British Flora - Loutlon's Hortus Britannicus - - - ,, ,, Lignosus Londinensis - ,, Encyclop^diaof Trees & Shrubs ,, ,, Gardening ,, ,, Plants J, „ Agriculture ,, Suburban Garden aud Villa Com- panion - - - - ,, Cemeteries and Churchyards - Rcpton's Landscape Gardening aiid Land- scape Architecture - - - - nivers's Rose Amateur's Guide Roberts on the Vine .... Rogers's Vegetable Cultivator - Smith's Introduction to Botany ,, English Flora .... „ Compenilium of English Flora - CHRONOLOGY. Blair's Chronological Tables - Nicolas's Chronology of History Riddle's Ecclesiastical Chronology - Tate's Horatius Restitutus ... Wathen's Chronology of Ancient Egypt ■ COMMERCE AND MERCANTILE AFFAIRS Kane's (Dr.) Industrial Resources of Ireland . - - . - . 1 Lorimer's Letters to a Young Master 31 Ma M*Culloch's Dictionary of Commerce and Commercial Navigation Spackman's Statistical Tables Steel's Shipmaster's Assistant ... GEOGRAPHY AND ATLASES. Butler's Sketch of Ancient and Modern Geography .... „ Atlas of Modern Geography ,, ,, Ancient Geography Hall's New General Atlas ... M*Culloch*s Geographical Dictionary Malte.Brun's Geography Murray's Encyclopaedia of Geography HISTORY AND CRITICISM. Adair's (SirR.), Memoir of a Mission to Vienna Addison's History of the Knights Templars Bell's History of Russia .... Blair's Chron. aud Historical Tables Bloorafield's Translation ofThucvdides - ,, Edition of Tbucydidis - Cooley's History of Maritime and Inland Discovery ...... Crowe's History of France ... Dunham's History of Spain and Portugal ,, History of Europe during^the Middle Ages .... ,, History of the German Empire „ History of Denmark, Sweden, and Norway ... Pages Dunham's History of Poland - - .10 Fergus's History of United States of America 10 Grant (Mrs.) Memoir and Corespondence 11 Grattan's Historv of Netherlands . .11 Halsted'sLifeof Richard III. - - li Horslev's (Bp.) Biblical Criticism . - 14 Jeffrey's (Lord) Contributions to the Edinburgh Review - - - . 16 Keightley's Outlines of History - . 16 King's (Lord) , Speeches and Writings (with Memoir) ..... 16 Laing's Kings of Norway - - - 16 Macaulay's Essays contributed to the Edinburgh Review - . - - 20 Mackintosh's History of England . - 20 ,, Miscellaneous Works . 20 M'CuUoch's Dictionary, Historical, Geo. graphical, and Statistical - . . 20 Maunder's Treasury of History - . 22 Moore's History of Ireland . - .23 Muller's Mythology 23 Nicolas's Chronology of History - .24 Rome, History of 26 Russell's Correspondence of the Duke of Bedford ....-.- 6 Scotfs HlstoiT of Scotland - - - 27 Sismondi's History of the Fall of the Roman Empire - - - 27 ,, Historv of the Italian Re- publics - - - - 27 Stebbing's History of the Christian Church 28 ,, History of the Reformation . 28 Switzerland, History of - - - - 29 Sydney Smith's Works - ... 27 Thirhvall's History of Greece ... 30 Tooke's History of Prices - . - 30 Turner's History of England . . 31 JUVENILE BOOKS, Iiicludint; Mrs. MurceCs yVorks. Boy's (the) Country Book, By W. Howitt 15 „ Own Book .... 6 Howitt's (M.) Child's Picture and Verse Book - - - - 14 „ (W.) Jack of the Mill - - 14 Ladies' (the Young) Book ... 32 Marcet's Conversations — On the History of England - - 21 On Chemistry 21 On Natural Philosophy • - - 21 On Political Economy - - - 21 On Vegetable Physiology . - - 21 On Land and Water . - - - 21 Marcet's the Game of Grammar - -21 ,, Mary's Grammar - - - 21 ,, Lessons on Animals, etc. - - 22 „ Conversations on Language - 21 Marryat's Masterman Ready - - - 22 „ Settlers in Canada ... 22 Maunder's Universal Class Book - - 22 Pycroft's fthe Rev^J.), English Reading Summerly s (Mrs. Felix) Mother's Priu MEDICINE. Bull's Hints to Mothers - „ Management of Children Copland's Dictionary of Medicine • EUiotson's Human Physiology Frankum on Enlarged Abdomen Holland's Medical Notes - - - - Maeleod On Rheumatism ... Marx and Willis (Drs.) On Decrease of Disease ...... Pereira On Food and Diet Recce's Medical Guide . . . - Sandby On Mesmerism ... 2U 1U CATALOGUE OF NEW WOUlvS. MISCELLANEOUS. Beale's (Miss) Vale of the Towcy Black's Treatise on Brewing: - liray's Philosophy ot Necessity CKvendish's Debates (Uavers's Forest Life Colto l)e Morgan On Probabilities - Good's Book of Nature - - - Graham's English . - - - ,, Helps to English Grammar Guest's Mabinogion - . - . Hand-Book of Taste - . . - Hobbes (Thos.), English Works of Holland's Progressive Education Howitt's Uural Life of England ,, Visits to Remarkable Places ,, Student-Life of Germany - ,, Rural and Social Life of Gc many . . - - ,, Colonization and Christianity ,, German Experiences Humphreys' Illuminated Books Jeffrey's (Lord) Contributions to the Edinburgh Review - - - - Laing's (S.,jun.) Prize Essay On National Distress ------ Letters on American Debts - - - Life of a Travelling Physician - Loudon's (Mrs.) Lady's Country Companiol Macaulav's Critical and Historical Essays Mackintosh's 'SirJames^ Miscellaneous Works Marx and Willis (Drs.) On Decrease of Disease ------- Miiller's Mythology - - - - - Peter Plymlej's Letters . . . . Prism of'lmagination (The) - _ - Pycroft's English Reading Sandby On Mesmerism - - - - Seaward's (Sir E.) Narrativeof his Ship- wreck - Smith's (Rev. Sydnev) Works Summerly's (Mrs. Felix) Mother's Primer Taylor's Statesman . - - - - Walker's Chess Studies - - . - WiUoughby's (Lady) Diary - - - NATURAL HISTORY IN GENERAL. Callow's Popular Coni-hology - - - 8 Gray's Figures of Molluscous Animals - 12 „ anu Mitchell's Ornithology - - 12 Kirby and Spence's Entomology - - 17 Lee's Taxidei my - - - - 18 „ Elements of Natural History - - 18 M.arcet's Conversations on Animals, etc. 22 Proceedings of the Zoological Society - 25 Stephens's British Coleoptera - - - 28 Swainson on the Study of Natural History 29 ,, Animals . - . . 29 „ Quadrupeds - - - - 29 „ Birds - .... 29 Animals in Menageries - 29 sh, Amphibians, & Reptiles 29 Ins mals Transactions of the Zoological Society Turton's Shells of the British Islands Wulcrton's Essays on Natural History Wcstwood's Classification of Insects 31 NOVELS AND WORKS OF FICTION. f:arl.-n'» Uo-scofTistclOn ... 8 Doctor (the; ... . . 10 (Mary) Diary ,, Home - ,, Neighl)Ours „ The H Fa Matryat's Masterman Jieady ughte nily, . Pages 21 Settle 1 Canada Rambles of the Empenir Ching Tih TroUope's (Mrs.) The Laurringtons - 31 ONE VOLUME ENCYCLOP/EDIAS AND DICTIONARIES. Blaine's Encyclopa;dia of Rural Sports - fi Brande's Dictionary of Science, Litera- ture, and Art .... - - 7 Copland's Dictionary of Medicine . - 9 Gwilt's Encyclopaedia of Architecture - 12 Johnson's Farmer's Encyclopaedia . Ifi Loudon's Encyclopaedia of Trees and Shrubs 18 ,, Encyclopaedia ofGardening ,, Encyclopaedia of Agriculture . 19 „ Encyclopaedia of Plants - - 19 ,, Rural Architecture 19 M'CuUoch's Dictionary, Geographical, Statistical, and Historical 20 ,, Dictionary, Practical, Theo- retical, etc. of Commerce 20 Murray's Encyclopaedia of Geography - 23 Savage's Dictionary of Printing . . 27 Ure's Dictionary of Arts, Manufactures, and Mines 31 Webster's Encyclopaedia of Dom. Economy 32 POETRY AND THE DRAMA. Aikin's (Dr.) British Poets - . - 27 Baillie's New Dramas .... 5 ,, Plays of the Passions - ■ ■ b Chalenor's Walter Gray - - - - 8 ,, Poetical Remains - - - 8 Goldsmith's Poems 30 Horace, by Tate ..... '.'9 L E. L's. Poetical Works ... 18 INIacaulay's Lays of Ancient Rome . - 20 Montgomery's Poetical Works - - 22 Moore's Poetical Works - - - - 23 ,, Lalla Rookh . - . - '23 ,, Irish Melodies - . - . '23 „ Illustrated by Maclise 23 Moral of Flowers '23 Shakspeare, by Bowdlcr - . - .27 Southey's Poetical Works - . . 28 ,, British Poets - . - - 27 Spirit of the Woods . - - .28 Thomson's Seasons . . . .30 POLITICAL ECONOMY AND STATISTICS. Kane's (Dr.) Industrial Resources of Ireland - - 16 M'CuUoch's Geographical, Statistical, and Historical Dictionary - 20 ,, Political Economy - - 21 Smith's Wealth of Nations - . - 28 Spackraan's Statistical Tables . . .28 Strong's Greece as a Kingdom - - 29 Tookc's History of Prices . - - 30 RELIGIOUS AND MORAL WORKS, ETC. Amy Herbert, Edited bv Prof. Sewell . 6 Biiilcy's Essays on the Pursuit of Truth - 6 Dloomticld's Greek Testament - - (i „ (-'ollegc and School ditto - fi ,, Greek and English Lexicon to New Tcstamcnl - - Border's Oriental Customs - - - 7 Burns's Christian Pliilosophy - ,, ,, Fragments - - - o Callcott's Scripture Herbal ' ' ' -l Dibdin's Sunday Library - . - - -9 Doddridge's Family Kxpositor - - - lU Kiiglisliman's Hebrew and Chaldee Cou- cordance _.---- 10 Ford's New Devout Communicaut - - 11 ,, Ccutiiry of Prayers - - • H Horsley's (Bp ) Biblical Criticism - - 14 Kippis's Collection of Hymns, etc. - • 16 Marriage Gift ------ ~2 Parkcs's Domestic Duties . - - 24 Pearson's Prayers for Families - - 24 Kiddle's Letters from a Godfather - - 25 Robinson's Greek and Knglish Lexicon to the New Testament . - - - 26 Sandford On Female Improvement - 26 „ On Woman - - - - 26 Spalding's Philosophv of Christian Morals 23 Tate's History of St. Paul - - - 29 Tayler's (Rev. C. B.) Margaret; or, the ' Pearl - - - 29 ,, Sermons - - 29 I' „ DoraMelder- - 29 Turner's Sacred History - - - - 31 Wardlaw On Socinian Controversy - 31 Willoughby-s (LaJy) Uiary - - - 32 RURAL SPORTS. Blaine'sDictionary of Sports • " • 5 Hansard's Fishing in Wales - - - 13 Hawker's Instructions to Sportsmen - 13 Loudoii's{Mrs.) Lady's Country Companion 18 llonald's Fly-fisher's F-ntomolog;,- - - 26 Thacker's Coursing Rules - - - 29 ,, Courser's Remembrancer - 311 THE SCIENCES IN GENERAL, AND MATHEMATICS. Bakewcll's Introduction to Geology - 5 Ualmain's Lessons on Chemistry - - 5 lirnnde's Dictionary of Science, Litera- ture, and Art - - " " "7 Brewster's Optics - - - - " 7 Conversations on Mineralogy - - ■ 9 De la Bcrhe on theGcology of Cornwall.etc. 10 Donovan's Chemistry - - - - 10 Egerton's Treatise on Photography - - 10 Farev on the Steam Kngine - - - 10 Fosbroke on the Arts, Manners, Manufac- tures, and Institutions of the Greeks and Romans 11 Greener's Science of Gunnery - - 12 ,, On the Gun - - - - 11 Herschcl's Natural Philosophy - - 13 ,, Astronomy - - - - 13 Holland's Manufactures in Metal - - 13 Hunt's Researches on Light - 16 Kane's Elements of Chemistry - - 16 K.ater and Lardner's Mechanics - - 16 l.ardner's Cabinet Cyclop.-cdia - - 1? ,, Hydrostatics and Pneumatics - 17 ,, and Walker's Klectricity - 1? ,, Arithmetic - - - - 17 ,, Geometry - - - - 17 ,, Treatise on Heat - - - 17 Lectures On Polarised Light - - - 17 I.loyil On Light and Vision - - - 18 Mackenzie's Physiology of Vision - - 20 Marcet's (Mrs.) Conversations on the M.I eley's Practical Mechanics Moselev's Engineering and Architecture Narriei'i's Elements of Geometry - - -" ,, Astronomy and Geodesy - - 26 Owen's Lectures On Comparative Anatomy 24 Parnell On Roads - - - - " "-^^ Pearson's Practical Astronomy - - -4 Phillips's Pal;eozoic Fossils of Cornwall, etc. 24 „ Guide to Geology - - " ^'^ ,, Treatise on Geology - - - 24 „ Introduction to Mineralogy - 24 Poisson's Mechanics - - - 24 Portlock's Report on the Geology of Londonderrv - - - - ■ 'x! Powell's Natural Philosophy - - - 2o Roberts's Dictionarv of Geology - - 26 Sandhurst Mathematical Course - - 26 Scoresby's Magnetical Investigations - 27 Scott's Arithmetic and Algebra - - 26 Thomson's Algebra ----- 30 Wilkinson's Engines of War - - - 32 Wood On Railroads - - • - 32 TOPOGRAPHY AND GUIDE BOOKS. Addison's History of the Temple Church 5 ,, Guide to ditto - - - - 5 Britton's Picture of Loudon - - - ( Hewitt's German Experiences - - - lo TRANSACTIONS OF SOCIETIES. Transactions of the Entomological Society 30 ,, Zoological Society - 30 J, Linniean Society - 30 ,, Institution of Civil Engineers - - 31 Roy.al Institute of British Architects - 30 Proceedings of the Zoological Society - 25 TRAVELS. Allan's Mediterranean . - - - .5 Beale's (Miss) Vale of the Towey - - 6 China, Last Year in . - - - 8 Chorley's Music and Manners in France and Germany ----- 9 Dc Custine's Russia - - - - 9 Harris's Highlands of Ethiopia - - 13 Howitt's Wanderings of a Journeyman Tailor 15 ,, German Experiences - - - 15 Laing's Notes of a Traveller - - - 17 ,, Residence in Norway - - - 17 „ Tour in Sweden - - - - 17 Life of a Travelling Physician - - - IS Modern Syrians ----- 22 Postans's Sindh ----- 25 Seaward's Narrative of his Shipwreck - 27 Strong's Greece as a Kingdom - - 29 Wilde's Voyage to Madeira, etc. - - 32 VETERINARY MEDICINE Field's Veterinary Records - - - 11 Morton's Veterinary Toxicological Chart 23 ,, ,, Medicine - - 23 Percivall's Hippopathology - - - 24 ,, Anatomy of the Horse - - 24 Spooner on the Foot and Leg of the Horse 23 Turner On the Foot of the Horse - - 31 White's Vcterinarv Art - - - - 32 „ Cattle Medicine ... 32 CATALOGUE. ADAIR (Sill ROBERT)— AN HISTORICAL MEMOIR OF A MISSION TO THE COURT OF VIKNNA IN 1806. By the Right H.)norabli: Sir Robert Ailnii ,(i.C.l5. With a Selectiou from his Despatclies, published by permission of the proper Aulltoritics. 8vo. 18». cloih. "Sir Robert Adair's valuable Memoir needs no commendation. Its ohvioxts utility, the nature of its contents, and the name of the author, will command the notice and appreciation of statesm-'n and historians,-' — Athenteum. " The vindication of Mr. Fox, from the obsirvations of Mr. Gentz and others, iscomplete ; and the Memoir is altogether a work which must be deferred to by future historians us the authority on the important affairs of which it treats."— Tail's Magaiilic. AIKIN.-THE LIFE OF JOSEPH ADDISON. lllustrrited by many of his Letters aini Privntc Papers never before published. By Lucy Aikin. 2 vols. postSvo. with Portrait from Sir Godfrey Knellcr's Picture. ISJ- clotli. "In the execution of her labour. Miss .rlihin has exercised praiseworthy diligence; she has ransacked among those fine and inexhaustible sources of personal and national interest —family papers, and has succeeded in rescuing from the obscurity of worm-eaten chests, and from the bondage of red tape, many documents which thyow light on the most doubtful parts of Addison's history, and relieve his character from the reproaches attempted to be cast on it. She has produced, both in style and mutter, a very interesting work, creditable to her feelings and talents, and honourable to her industry."--liritiimni\. ALLAN.— A PICTORIAL TOUR IN THE MEDITERRANEAN; Comprising Malta, Dalmatia, Turlscy, Asia Minor, Grciian Archipelago, Egypt, Nubia, Greece, Ionian Islanils, Sicily, Italy, and Spain. By J. H. Allan, Member of the Atlicnian Arclueological Society, and of the Egyptian Society of Cairo. Imp. 4to. containing upwards of 40 I,itlini;raphed Drawings, and 70 Wood Engravings, 3/. 3s. cloth. "A most ariist-tike and interesting work, full of beautiful views, and interspersed with many charming woodcuts of scenery and antiquities.^^ — Literary Gazette. ADDISON.— THE KNIGHTS TEMPLARS. By C.i;. Addison, of the Inner Temple. 2d Edition, enlarged, 1 vol. square crown 8vo. with Illustrations, ISs. cloth. ADDISON.— THE TEMPLE CHURCH IN LONDON: Its History and Antiquities. By C. G. Addison, Esq., of the Inner Temple, author of "The History of the Knights Templars." Square crown 8vo. with 6 Plates, 5s. cloth. Also, A FULL AND COMPLETE GUIDE, HISTORICAL AND DESCRIPTIVE, TO THK TEMPLE CHURCH. (From Mr. Addison's "History of the Temple Church.") Square crown Svo. 35. sewed. AMY HERBERT. By a Lady. Edited by the Rev. William Scwell, B.D. of Exeter College, Oxford. 2vol3. foolscap Svo. 9s. cloth. "' Amy Herbert' paints nature to the life. It is by ' a Lady,' for whose soundness Mr. fleierll is sponsor. It is admirably adapted for the youn^ of the higher classes, and we sincerely hope it mail not be the fair author's last production." — Christian Rcmcnibrnncer. BAILEY. -ESSAYS ON THE PURSUIT OF TRUTH, And on the Pi ogress of Knowledge. By Samuel Bailey, author of "Essays on the Formation and Publication of Opinions," "Berkeley's Theory of Vision," etc. 2d Edition, revised and enlarged, Svo. 9s. 6d. cloth. " Mr. Bailey is an admirable writer, both as to the general tone of thought and sentiment, and as to his style, which is clear, forcible, and elegant. On the class of subjects to which he has chief y directed his attention, no man writes what is more worthy of being read, or what is acceptable to a larger class of readers. The peculiar quality of his powerful essays Is the practical and useful conviction they produce oj truths as obvious as they are important, but which are strangely neglected by the majority of mankind. We do not often meet with a book which we can more strongly recommend."— imimrcT. BAILLIES (JOANNA) NEW DRAMAS. 3 vols. Svo. If. Ifis. boards. BAILLIES fJO.\NNA) PLAYS ON THE PASSIONS. 3 vols. Svo. W. Us. 6rf. boards. BAKEWELL.— AN INTRODUCTION TO GEOLOGY. Intended to coiivev Practical Knowledge of the Science, and comprising the most important recent Discoveries'; with Explanations of the Facts .and Phenomena which serve to confirm or invalidate v.arious Geological Theories. By Robert Bakewell. Fifth Edition, considerably enlarged, Svo. with numerous Plates and Woodcuts, 21». cloth. BALMAIN.- LESSONS ON CHEMISTRY, For the Use of Pupils in Si.hnols, .Iiiiiiur Students in Universities, and Renders who wish to learn the fundamental Prinei|des and leading Facts: with Questions for Examination, Glossaries of Chemical Terms and Chemical Symbols, and an Index. By William H. BalniBin. With numerous Woodcuts, illustrative of the Decompositions, foolscap Svo. fij. cloth. CATALOGUE OF NEW WORKS BAYLDON.-ART OF VALUING RENTS AND TILLAGES, And the Tenant's Right of Entering and Quitting Farms, explained by several Specimens of Valuations; and Remarks on the' Cultivation pursued on Soils in different Situations. Adapted to the Use of Landlords, Land-Agents, Appraisers, Farmers, and Tenants. By J. S. Bayldon. 6th Edition, corrected and revised by John Donaldson, Land-Steward, author of a "Treatise on Manures and Grasses." 8vo. lOj. 6ii. cloth. BAYLDON. — TREATISE ON THE VALUATION OF PROPERTY FOR THE POOR'S RATE; showing the Method of Rating Lands, Buildings, Tithes, Mines, Woods, Navigable Rivers and Canals, and Personal Property; with an Abstract of the Poor Laws relating to Rates and Appeals. By J. S. Bayldon, author of "Rents and Tillages." 1 vol. 8vo. 75. 6rf. boards. BEALE (ANNE)-THE VALE OF THE TOWEY ; Or, Sketches in South Wales. Bv ,\niic Scale. Post Svo. 10.». 6d. cloth. " The prrusiil n/this agrernhle volume of Sketches hiis afforicd us cimsiderable nmmement. Miss Benle is a lively and i?itelligeia chronicler, who tells her stories in a manner to make them run on smooth and pleasantly " —Vn'iteA Service Gazette. BEDFORD CORRESPONDENCE. — CORRESPONDENCE OF JOHN, FOURTH DUKE OF BEDFORD, selected from the Originals at Woburn Abbey: with Introductions by Lord John Russell. Svo. vol. 1 (ir-C-lSl, 18». cloth; vol. 2 (1/49-6 '), 15s. cl. ** The second volume includes a correspondence having relation to the period from the Peace of Aii-la-Chapelle to the death of George II. Its most remarkable portion bears upon an important question, on which there still eaist some differences of opinion, ri-. the intrigues which led to the junction of the Duke of Newcastle and Pitt, in 1757. The letters respecting the state of Ireland under the riceroyalty of the Duke of Bedford also, are nut a little interesting."— t'lotnm^^ Herald. •,• /"(.;. ///. to complete the work, is in preparation. BELL.— LIVES OF THE MOST EMINENT ENGLISH POETS. By Robert Bell, Esq. 2 vols, foolscap Svo. with Vignette Titles, 12s. cloth. BELL.— THE HISTORY OF RUSSIA, From the Earliest Period to the Treaty of Tilsit. By Robert Bell, Esq. 3 vols, foolscap Svo. with Vignette Titles, 18s. cloth. BIOGRAPHICAL DICTIONARY Of the Society for the Diffusion of Useful Knowledge. Half-volumes. 1 to 7- (A.\ to Az-Zubevdi -comprising the letter A) . Svo. 12s. each, cloth. *,* Published Quarterly .— The work will probably not exceed Thirty Volumes. " We have carefully examined the articles under letter A, now completed, and have no reason to complain of any want of tinijormity. There seems to have been, on the whole, a judicious apportioning of space, according to the importance of the individual. In order to secure this necessary uniformity, a societii, which had no pecuniary projit as its end, was more likely to succeed than a private publisher, or body of publishers. In style, execution, and completeness, the lives are far superior to thtise of any biographical dictionary with which we are acquainted. The only one, indeed, with which, for completeness, it can be compared, is the I'rench ' Biographic Universele,' but in this respect it has very greatly the advnu- ta^e.'' [The reviewer ii.stitates a comparison in favour of the English work, too long to be quoted, and ends his parairraph as follows :]-" So that the .Society's Dictionary must be regarded as a labour not only for Great Biitain, ^ut for Europe. In all the articles there are two points in which they are fuller and more accurate than any previous work of the kind : and these are, the titles, dates, and places of publication of books, and their editions, and the sources from whence the materials have been derived for the biography."— AtheniEUia. BLACK— A PRACTICAL TREATISE ON BREWING. Based on Chemical and Economical Principles: wilh Formula; for Public Brewers, and Instructions for Private Families. By William Black. Third Edition, revised and cor- rected, with considerable Additions. The Additions revised by Professor Graham, of the London University. Svo'. 10s. 6d. cloth. "This comprehensive and informing essay will be found invaluable to the practical brewer and private families: to the former we re'cooimend it as a work ably treating of their art; to the latter, as one which they will Jind an ej/lcimt and correct guide. This edition fully bears out the statement on the title-page — that it has been ' much enlarged and improved.'" Chemist. BLAINE.— AN ENCYCLOP/EDIA OF RURAL SPORTS; Or, a complete Account, Historical, Practical, and Descriptive, of Hunting, Shooting, Fishing, Racing, and other Field Sports and Athletic Amusements of the present day. By Delabere P. Blaine, Esq., author of " Outlines of the Veterinary Art," " Canine Pathology," etc. etc. With nearly 600 Engravings on Wood, by R. Branston, from Drawings by Aiken, T. Land- seer, Dickes, etc. 1 thick vol. Svo. 21. Ws. cloth. BLAIR'S CHRONOLOGICAL AND HISTORICAL TABLES, From the Creation to the present Time ; with Additions and Corrections from the most authen. tit Writers ; including the Computation of St. Paul, as connecting the Period from the Exode to the Temple. Under the revision of Sir Henry Ellis, K.H., Principal Librarian of the British Museum. Imperial Svo. 31s. 6d. half-bound morocco. " The arrangement adopted iu this extended edition of Dr. Blair's valuable work is most adviirable; each table comprisiua the space of half a century, and exhibiting, in parallel columns, contemporary kings and rulers, the chief events that marked the history of their tune, and the most celebrated characters who flourished in their age. As an aid to the study of history, and as a general work of reference, the tables are of great utility ; and we are satisjird that, as their merit becomes known, no one to whom they arc accessible will ever take up a history without hnviug this volume open before him. It is to our view an indispensable companion'to every collection of history, however small."— Mrit^nnUi. PRINTED FOR LONGMAN, BROWN, AND CO. / BLOOMFIELD.— HISTORY OF THE PELOPONNESIAN WAR. By TliutvdMles. Newly Translated into English, and accompanied with very copious Notes, Philnloijiral and Explanaton-, Historical and Geographical. By the Rev. S. T. Bloomfield, D.U. F.S.A. 3 vols. 8vo. with Maps and Plates, -21. 5s. boards. BLOOMFIELD— HISTORY OF THE PELOPONNESIAN WAR. By Thucydides. A New Recension of the Text, with a carefully amended Punctuation ; and copious Notes, Critical, Philological, and Explanatory, almost entirely original, but partly selected and arranged from the best Expositors : accompanied with full Indexes, both of Greek Words and Phrases explained, and matters discussed in the Notes. The whole illus- trated by Maps and Plans, mostly taken from actual Surveys. By the Rev. S.T. Bloomfield, D.D. F.S.A. 2 vols. 8V0.38J. cloth. BLOOMFIELD.— THE CREEK TESTAMENT : With copious English Notes, Critical, Philological, and Explanaton-. Bv the Rev. S.T. Bloomfield, D.D. F.S.A. oth Edit, improved, 2 vols. 8vo. with a Map of Palestine, 4U». cloth. BLOOMFIELD.-COLLECE AND SCHOOL CREEK TESTAMENT; With English Notes. By the Rev. S. T. Bloomljeld, D.D. Third Edition, greatly enlarged and very considerably improved, accompanied with a New Map of Syria and Palestine, adapted to the New Testament and Josephus, and an Index of Greek Words and Phrases explained in the Notes. 12mo. 10s. 6rf. cloth. BLOOMFIELD.— CREEK AND ENGLISH LEXICON TO THE NEW TESTAMENT: especially adapted to the use of Colleges, and the Higher Classes in Public Schcjdls : liutalso intended as a convenient Manual for Biblical Students in general. By Dr. Bloomfield. Foolscap Svo. 9s. cloth. BOY'S OWN BOOK (THE): A Complete F^ncyclopsedia of all the Diversions, Athletic, Scientific, and Recreative, of Boy- hood and Youth.' 2Uth Edition, square 12mo., with many Engravings on Wood, Cs. boards. BRANDE.— A DICTIONARY OF SCIENCE, LITERATURE, AND ART; Comprising the Historv, Description, and Scientific Principles of every Branch of Human Knowledge ; with the D'erivatiou and Definition of all the Terms in general use. Edited by W. T. Brande, F.R.S.U. and E. ; assisted by Joseph Cauvin, Esq. The various departments are by Gentlemen of eminence in each. I very thick vol. Svo. pp. 1352. Illustrated by Wood- engravings, 3/. cloth. London, 1842. BRAY.-THE PHILOSOPHY OF NECESSITY; Or, the Law of Consequences as applicable to Mental, Moral, and Social Science. By Charles Bray. 2 vols. Svo. 155. cloth. BREWSTER.— TREATISE ON OPTICS. By Sir David Brewster, LL.D. F.R.S. etc. New Edition. 1 vol. foolscap Svo. ViguetteTitle, aiid 176 Woodcuts, Gs. cloth. BRITTON— THE ORIGINAL PICTURE OF LONDON: With a Description of its Environs. Re-edited and mostly re written, byJ.Britton, F.S.A. etc. 28th Edition, with upwards of lUO Views of Public Buildings, Plan of the Streets, and Two Maps, 18mo. 95. neatly bouud ; with the Maps only, 6s. bound. BULL.-HINTS TO MOTHERS, For the Management of Health during the Period of Pregnancy and in the Lying-in Room ; with an Exposure of Popular Errors in'connexiou with those subjects. ByThomasBull, M.D. Physician Accoucheur to the Finsburv Midwifery Institution, etc. etc. -Ith Edition, revised and considerably enlarged. Foolscap Svo. 7s. cloth. BULL.-THE MATERNAL MANAGEMENT OF CHILDREN, In HEALTH and DISEASE. By Thomas Bull, M.D. Fooliscap Svo. /s. cloth. " lijceltent guides, and deserve to be genemlly known." Johnson's Medico-Chirurgical Review. BURDER. -ORIENTAL CUSTOMS, Applied to the Illustration of the Sacred Scriptures. By Samuel Burder, A.M. 3d Edition, with additions, foolscap Svo. 8s. 6</. cloth. CONTENTS. louses and Tents-Marriage-Children— Ser- vants— Food and Drink— Dress and Clothing — Presents and Visiting — Amusements- Books and Letters -Hospitality-Travelling -KcspeetandHouour— Agriculture— Cattle Is, Insects, and Reptiles — -Kings and Government— ntb — Religion — Time and ne— Funerals, etc. BURNS.— THE PRINCIPLES OF CHRISTIAN PHILOSOPHY; Containing the Doctrines, Duties, Admonitions, and Consolations of the Christian Religion. By John Burns, M.D. F.R.S. ath Edition, 12mo. 7s. boards. CONTENTS. the Future State of Happiness ; of Personal Duties; of Relative Duties; of the Duties toGoil; of the Admonition Man ii created for a Future State of Happiness; on the Means by which a Future Slate of liayylln-aii is pro'cured ; of what is r(M|uired of Man that he may obtain a Future State of Happineis ; of the Nature of the Future State or llappiiitKH ; of the Preparation for Consolations alfurded by the Christian Re ligiou. CATALOGUE OF NEW WORKS BURNS— CHRISTIAN FRAGMENTS; Or, Hemarka on the Nature, Precepts, niul Comfort* of Religion. By John Burns, M.D. F.U.S. Professor of Surgery in the University ol Glasgow, author of " The Principles of Christian Philosophy." Foolscap 8vo. 5s. cloth. " Fifty-six. more or less rxtended, ' Fragmentt,' on varioin doctrinal, crprrimcutat, and practical subjects. The author manifests throughout n sound judgment, a cultivated literary taste, and, best of alt, a heart deeply impressed with the solemn realities of rcliaion. His sentiments are evangelical, and his spirit devout. Some of the 'Fragments' referring to suffering, sickness, and death, and written, as the author iriforois us, under a recent deep aj/liction, arc pecnliarUj spiritual and proJitahlcJ'—W'-MchmM. BUTLER.-SKETCH OF ANCIENT AND MODERN GEOGRAPHY. By Samuel Butler, D.l)., late Lord Bishop of Lichiielil and Coventry; and formerly Head Master of Shrewsbury School. New Edition, revised by his Son, 8vo. 9». boards. The present edition has been carefully revised by the author's son, and such alterations introduced as continually progressive discoveries and the latest information rendered neces- sary. Recent Travels have been covstantly consulted where any doubt or difficulty seemed to require it; and some additional matter has been added, both in the ancient and modern part. BUTLER.-ATLAS OF MODERN GEOGRAPHY. By the late Dr. Butler. New F.dition ; consisting of Twenty-three coloured Maps, from a New Set of Plates. 8vo. with Index, 12j. half-boiind. BUTLER.-ATLAS OF ANCIENT GEOGRAPHY; Consisting of Twenty-three coloured Maps. With Index. By the late Dr. Butler. New Edition. 8vo. 12j. half-bound. «.* The above two Atlases may be had, in One Folame,4to. 24». half-hound. CALLCOTT.-A SCRIPTURE HERBAL: With upwards of 120 Wood Engravings. By Lady Callcott. Square orownSvo., pp.568, libs, cloth. "' My chief object and aim in writing this little booh,' commences the amiable and noble authoress, ' has been to induce those who read and love Clod's written Word, to read and love the great nnwrittev book which he has everywhere spread abroad for our learning.' The 'chief object and aim' of this pious and gifted woman cannot fail in its object. Indeed, we mail almost to a certainty pronounce for this labour of her devotional love a success which her most Christian sanguine wishes could not have anticipated for it. The authoress has termed it a small book, and may have at first intended it as such ; it is gratifying that it is otherwise, for a single page could not be spared, so redolent is each with the best of material. It is remarked in the preface that the work was written while the body was in a state of ill health -what a contrast must the spirit have presented'. May it long dirtct the head and hand to add thus to our useful /i/era(!<rir.— Standard. CARLEN (EMILIE)-THE ROSE OF TI3TELON : A Tale of the Swedish Coast. By Emilie Carlen. Translated from the original Swedish. 2 vols, post 8vo.2l3. boards. •* There are a vigour and a rapidity of action, and an artist-like skill displai/ed in working out the events of this clever story, which make it very attrnctine, and sustain the reader's interest unbroken from the first to the last page.^' — Magazine of Domestic Economy. CATLOW.— POPULAR CONCHOLOCY; Or, the Shell Cabinet Arranged ; being an Introduction to the modern System of Conchology ; with a sketch of the Natural History of the Animals, an account of the Formation of the Shells, and a complete Descriptive List of the Families and Genera. By Agnes Catlow. 1 vol.fcap.8vo. with ;il2 Woodcuts, Ws.l'td. cloth. " This admirable little work is designed to facilitate the study nf natural history, daihi becoming more attractive, not onlyfiom its intrinsic interest, hut also fmm its mulliplird relations with geology. It will famish the voung entomologist with an rlrmeutary mnviiul, which, though scientific in its form, is. by the simplicity of its method, and the familiarit,/ of its style, calculated rjf'ectaally to assist him iu the early steps oj his progress in this fascinating ;>«rjnl7."— St. James's Chronicle. CIIALENOR. — POETICAL REMAINS OF MARY CHALENOR. Kcp.Svo. is. cloth. CHALENOR. -WALTER GRAY, A Ballad, and other Poems ; including the Poetical Remains of Mary Chalcnor. 2d Edition , with Additions, fcp. 8vo. Rj. cloth. " As the simple and spontaneous effusions of a mind apparently filled with feelings which render the fireside happy, and untiticlured with affectation or verbiage, they may with henejit be received into the ' happy homes of England,' and offered as a gift to the youthful of both sexes."— Ch&m\ieTs' Edinburgh Journal. CHINA.— THE LAST YEAR IN CHINA, To the Peace of Nanking: as sketched in Letters to his Friends, bv a Field Officer activi-lv employed in that Countrv. With a few conclu.ling Remarks on our Past and Future Policy in China. 2d Edition, revised. I'uolscap avo. with Map, /s. cloth. CHINESE NOVEL.— RAMBLES OF THE EMPEROR CHING TIH IN KEANG NAN: a Cliinese Tale. Translated by Tkin Shen ; with a Preface by James Leggc, D.I). 2 voLs. post Svo. 21s. cloth. " These rambles oJ the Unroun A Irasehidof the Celestial Empire ^iue a very curious, and, at thepresent moment, a peculiarly interesting view of Chinese opinions, usages, and insti- tutions."— Ti'a'a Magaiine. PRINTED FOli LONGMAN, BROWN, AND CO. 9 CHORLEY— MUSIC AND MANNERS IN FRANCE AND GERMANY: A Series of Travelling Sketches of Art ami Society. By H. F. Chorley, Esq., author of " Couti," 3 vols, post Svo. 31s. 6d. boards. CL.WERS.— FOREST LIFE. ByMaryClavers, an Aclu.il Settler; autoor of " A New Home, Who'll Follow?" 2 vols, fcap. Sto. pp. 642, l'2s- cloth. COLTON.— LACON; OR, MANY THINGS IN FEW WORDS. Bv the Rev. C. C. Colton. New Edition, Svo. 12j. cloth. CONVERSATIONS ON BOTANY. 'Jth Edition, improved, pp. 302, foolscap Svo. with 22 Plates, 7J.6d. cloth; with the Plates coloured, 12». cloth. The object of thistrork is to enable children and young persons to acquire a knowledge oj the vegetable productions of their native country, by introducing to them, in a familiar manner, the principles of the Linncean System of Botany. For thispurpose, the arrangement of Linnxus is briefly explained; a native plant of each class, tcith a fete exceptions, is examined, and illustrated by an engraving ; and a short account is added of some of the prineipal foreign species. CONVERSATIONS ON MINERALOGY. With Plates, engraved by Jlr. and Mrs. Lowry, from Original Drawings. 3d Edition, eularijed. 2 vols. 12mo. Us. cloth.' COOLEY.— THE HISTORY OF MARITIME AND INLAND DISCOVERY. By W. D. Cooler, Esq. 3 vols, foolscap Svo. with Vitrnette Titles, ISs. cloth. COPLAND.— A DICTIONARY OF PRACTICAL MEDICINE; Comprising General Pathology, the N.ature and Treatment of Diseases, Morbid Structures, and the Disorders especially incidental to Climates, to Sex, and to the different Epochs of Life, with numerous approved Formula of the Medicines recommended. By James Copland, M.D., Consulting Phvsician to Queen Charlotte's Lving-in Hospital; Senior Physician to the Royal Infirmary for Children ; Member of the Roval College of Physicians, London ; of the Medical and Chirurgical Societies of London and iicrlin, etc. Vols. 1 and 2, ,Svo. 3». cloth ; and Part 9, -Is. C,d. boards. *.* To be completed in one more Volume. CROCKER'S ELEMENTS OF LAND SURVEYING. Fifth Edition, corrected throughout, and considerably improved and modernized, bv T. G. Bunt, Land Surveyor, Bristol. To which are added, TABLES OF SIXFIGUKK LO(;.\UITHMS, etc., superintended by Richard Farley, of the Nautical Almanac Establi.sh- mcnt. 1 vol. post Svo. 1'2». cloth. ♦,♦ The vork throughout is entirely revised, and much new matter has been added; there are nete chapters, containing very full and minute Directions relntinn to the modern Practice of Surveying, both with and without the aid of angular instruments. The method of Plotting Estates, and castingior computing their Areas, are described, etc. etc. The chapter on Levelling also is new. CROWE.— THE HISTORY OF FRANCE, From the Earliest Period to the Abdication of Napoleon. By E. E. Crowe, Esq. 3 voU. foolscap Svo. with Vignette Titles, ISj. cloth. DAIILM.VNN.— HISTORY OF THE ENGLISH REVOLUTION. By F. C. Dahlmann, late Professor of Iliston- .it the Unircr.'iity of Goltingen. Translated from the German, by H. Evans Lloyd. Svo. lOj. M. cloth. " Professor Duhlmuvn's hook is, in short, a rapid sketch of the whole nf what uc call the Modern History of England, Jrom its start at the Coroualion of Henry the Seventh, to its intermediate tetlfemrnt at the ( oronatiou of llilliam the Third. fVe have no English sum- maru of the history it relates St brief, eomp, nitious, and impartial. M. Dahlmann is a very earnest as well as intelliL^rnt writer: and the steady advance of Hie popular principle in England, through an almost uninterrupted march of to o centuries, is startlivgly refected ,u hi, clear and transparent relation. Mr. Lloyd's translation is very well executed."— Kxammer. DAVY (SIR lIUMl'ilRY;. -AGRICULTURAL CHEMISTRY: With Notes by Dr. John Davy. Gth ?;dilion, Svo. with 10 Plates, \hs. cloth. limal Origin ; Manures of Mineral Origin, or Fossil Manures ; Improvement of Lands by Burning ; Experiments on the Nutritive Qualities of different Grasses, etc. Introduction; The General Powers of Matter which Influence Vegetation: the Organiza- tion of Plants ; Soils ; Nature and Constitu- tion of the Atmosphere, and its Influence on Vegetables; Manures of Vegetable and DK CUSTINE.— RUSSIA. By the Marquis De Cuitine. Translated from the French. 2d Edition, 3 vols, post Svo. SU.Crf. cloth. " ire are inclined to think -and it is n painful reflection- that ifons. Pe Custine's remark- able volumes contain a more accurate account of the slate and condition of Hussia than any other work of recent date, without exception. The author hasmnnifeslly penetrated through that superficial glitter andgori(eou, array which have blinded the eyes of loo many travellers to the imperfections and defects of this great empire, and has shewn it us it really is . To do Mil in the rate of Russia requires many and favourable opportunities of observation, con- siderable shrewdness, and a courage and determination not easily to be daunted: ull which MonM. I)e funline b.:s proved himself to have possessed in an eminent degree; and the result IS, a work which those who are desirous to know Hunia as it realty is, and not as it would fain impose itself on the world to be, would do well („ consult, lie firomise our readers equal surprise and plenlurr from the perusal of his very clever iioo*."-Geiilleman'H Mag. 10 CATALOGUE OF M F.W WORKS DE LA BECHE.-REPORT ON THE GEOLOGY OF CORNWALL, DEVON, AND WEST SOiMEUSF.T. By Henry T. Ue la Bcihe, F.R.S. etc., Director of the Ordnarict Geological Survey. Published bv Order of the Lords Commissioners of H. M. Treasury. Svo. with Maps, Woodcuts, and 12 larfje Plates, 14s. cloth. DE MORGAN.— AN ESSAY ON PROBABILITIES, .And on their Ap|ilicatiou to Life Contingencies and Insurance Offices. By Aug. De Morgan, of Trinity College, Cambridge. 1 vol. foolscap Svo. with Vignette Title, 6s. cloth. DOCTOR (THE), ETC. o vols, post Svo. -21. V2s. M. cloth. ^^ Admirably as the myitery of the ^Doctor' hat been preserved up to the present moment, there is no longer any reanon for affecting secresy on the subject. The author is Uohert Southey ; he acknowledged the fact shortly before his last illness to his most conjidential friend, an M.P. of high character. In n private letter from Mrs. Southey, dated february l7,1HW, she not only states the fact, but adds that the greater part of a sixth volume had gone through the press, and that Soutliey looked foricard to the pleasure of drauius; her into it as a contributor; giving her full authority to ajhrm that her husband is the author." Robert Bell, Esq., in The Story Teller. DODDHIDGE.— THE FAMILY EXPOSITOR; Or, a Paraphrase and Version of the New Testament : with Critical Notes, and a Practical Improvement of each Section. Bv P. Doddridge, D.D. To which is prefixed, a Life of the Author, by A. Keppis, D.D. F.R.S.'and S.A. New Edition, 4vols. Svo. It. 16». cloth. DONOVAN.— TREATISE ON CHEMISTRY. I?v Michael Donovan, Esq. M.R.I. A. Fourth Edition. 1vol. foolscap Svo. with Vignette Title, 6s. cloth. DONOVAN.— A TREATISE ON DOMESTIC ECONOMY. By M. Donovan, Esq. ftl.R.I.A., Professor of Chemistry to the Company of Apothecaries in Ireland. 2 vols, foolscap Svo. with Vignette Titles, 12s. cloth. DOVER. -LIFE OF FREDERICK II. KING OF PRUSSIA. By Lord Dover. 2d Edition, 2 vols. Svo. with Portrait, 2Ss. boards. DRU.MMOND.— FIRST STEPS TO BOTANY, Intended as popular Illustrations of the Science, leading to its study as a branch of general education. By J. L. Drummond, M.D. 4th Edit. I2mo.with numerous Woodcuts, 9s. boards. DUNHAM. -THE HISTORY OF THE GERMANIC EMPIRE. By Dr. Dunham. 3 vols. foolscapSvo. with Vignette Titles, 18s. cloth. TIIF, HISTORY OF EUROPE DURING THE HI.STORY OF POLAND. By THE MIDDLE AGES. By Dr. Du 4 vols, foolscap Svo. with Vignette Titles, 1/. 4s. cloth. THE HISTORY OF SPAIN AND PORTU- G.-VL. By Dr. Dunham. 5 vols, foolscap Svo. with Vignette Titles, 1/. lOs. cloth. TIIK HISTORY OF SWEDEN, DENM.\RK, AND NORWAY. By Dr. Dunham. 3 vols. foolscap Svo.with Vignette Titles, IBs. cloth. il. foolscap Svo. with Vignette Title, 6«. cloth. THF. LIVES OF THE EARLY WRITERS OF GRE.AT BRITAIN. By Dr. Dunham, R. Bell, Esq., etc. 1 vol. foolscap Svo. with Vignette Title, 6s cloth. THE LIVES OF BRITISH DRAM.'VTISTS. By Dr. Dunhatn, R. Bell, Esq., etc. 2 vols. foolscap Svo. with Viguette Titles, 12j. clotli EGERTON —A TREATISE ON PHOTOGRAPHY; Containing the latest Discoveries appertainini; to the Daguerreotype. CompUed from Com* munications by MM. Daguerre and Arago, and other Eminent Men of Science. By N. P. Lerebours, Optician to the Observatory, Paris, etc. Translated byJ.Egerton. Post Svo. with Plate of Apparatus, 7«* Gd. cloth. ** A translation of M. Lerebours^ celebrated * Treatise on Photography.* This work will be peculiarly acceptable to the scientijic worldy contatuxng^ as it does, the latest discoveries and improvements in the art of which it treats; together with a vast variety of practical instruc- tions^ valuable hints respecting the choice of plates, apparatus ^ etc.; indeed, all the details and minutiiB necessary to lead to successful results."— ExamineT. ELLIOTSON.— HUMAN PHYSIOLOGY: With which is incorporated much of the Elementary Part of the "Institutiones Physiologic^"' of J. F. Blumeiibach, Professor in the University of Gottingen. By John EUidtsou, M.D. Cantab. F.R.S. Fifth Edition. Svo., with numerous Wood-cuts, 2/. iJs. cloth. ENGLISHMAN'S HEBREW AND CHALDEE CONCORDANCE OF THE OLD TESTAMENT; being an attempt at a Verbal Connexion between the Original and the English Translations: with Indexes, a List of the Proper Names and their occur- rences, etc. etc. 2 vols, royal Svo. cloth, 31. 13j- firf ; large paper, 4/. 14.i. Grf. *' The labour bestowed upon this important work has seldom^ we should suppose, hteu equalled; and we have the fullest conviction, from the merely cursory es^nmination we are able to give to such a stjipendous task, that the result justijies all the labour, time, and money ea-pended upon it. Indeed, the whole book bears the most palpable evidence of honest carefulness and unwearied diligence — the points of prime worth in a Conrordatice ; and trherever we have dipped into its pages (about 18(10 , we have, in every case, had our opinion of its neatness, accuracy, and lucid order, conjinnt d arid increased.^^—lAtCTRry Gazette. FAREY.-A TREATISE ON THE STEAM-ENGINE, Historical, Practical, and Descriptive. By John Farcy, Engineer. 4to. Illustrated by numerous Woodcuts, and 25 Copper-plates. 5/. os. in boards. FERGUS.— THE HISTORY OF THE UNITED STATES OF AMERICA, From the Discovery of America to the Election of General Jackson to the Presidency. By the Rev. H. Fergus. 2 vols, foolscap Svo. with Vignette Titles, 12s. cloth. PRINTED FOR LONGMAN, BROWN, AND CO. 11 I KIELD. - POSTHUMOUS EXTRACTS FROM THE VETERINARY RECORDS OF THK LATE JOHN FIELD. Edited by his Brother, Williiim Field, Vete- rinary Surgeon, London. 8vo. 8s. boards. "A colteclion of Temarliable cases of disease in the horse, observed bn the late Mr. Field, during his extensive prftctice; with a few papers on particular diseases, either read before the Veterinary Medical Society, or, seemingli/, sketched trith that end in ricir. To pass a decided judgment on the veterinarv value of the volume is beyond our power ; but the cases appear to be noted with great clearness in their symptoms, treatment, and post-mortem ciamivatiun. We should conceive the work likely to be of considerable use to veterinary surgeons,— who, luckv people! do not as yet appear overburdened with books on their business ; and not with- out interest to the medical practitioner, who would study comparative surgery as well as comparative anatomy." — Spectator. FORD. -THE NEW DEVOUT COMMUNICANT, .\ceorJiug to the Church of Enffland ; containing an Account of the Institution, Pravcrs, and Meditations, before and after the Administration, and a Companion at the Lord's Table. Bv the Rev. J.imes Ford, B.D. 7th Edit., ISmo. ij. Cd. bound in cloth, gilt edges; tcap. Svo. 35. Gd. bound. FORD.— A CENTURY OF CHRISTIAN PRAYERS, On FAITH, HOPE, and CHARITY: with a Morning and Evening Devotion. By the Rev. James Ford, B.U. 3d Edition, ISmo. 4s. cloth. FORSTER. -STATESMEN OF THE COMMONVJ/EALTH OF ENGLAND. With an Introductory Treatise on the Popular Progress in English History. By John Forsler, Esq. vols, foolscap Svo. with Original Portraits of Pym, Eliot, Hampden, Cromwell, and an Historical Scene after a Picture by Cattemiole, 1/. lOj. cloth. The Introductory Treatise, intended as an Introduction to the Study of the Great Civil War in the Seventeenth Century, separately, price 2«. Gd. sewed. The above 5 vols, form Mr. Forster's Portion of the Lives of Eminent British Statesmen, by Sir James Mackintosh, the Right Hon. T. P. Courtenay, and John J'orster, Esi). 7 vols, foolscap Svo. with Vignette Titles.lL is. cloth. FOSBROKE— A TREATISE ON THE ARTS, MANNERS, MANUFAC- TURES, and INSTITUTIONS of the GREEKS and ROMANS. By the Rev. T. U. Fosbroke, etc. i vols, foolscip Svo. with Vignette Titles, I'Js. clotli. FRANKUM. — DISCOURSE ON THE ENLARGED AND PENDULOUS ABDOMEN, shewing it to be a Visceral Alfection, .attended with Important Conse.iuenccs in the Human Economy ; with cursory Observations on Diet, Exercise, and the General Management of Health: for the use of the Dyspeptic. By Richard Frankum, Esq. Surgeon. The Second Edition, augmented, with a Dissertation on Gout, suggesting new Phvsioliigical Views as to its Cau,se, Prevention, and the best Course of Treatment. Fcap. Svo. 5j. cloth. GLEIG.— LIVES OF THE MOST EMINENT BRITISH MILITARY COM- MANDERS. By the Rev. G. R. Gleig. 3 vols, foolscap Svo. witli Vignette Titles, ISs. cloth. GLENDINNING — PRACTICAL HINTS ON THE CULTURE OF THE PINEAPPLE. Bv R. Glerulinning, Gardener to the Right Hon. Lord RoUe, Bicton. limo. with Plan of PincK-, 6j. clotli. GOOD.— THE BOOK OF NATURE. A Popular Illustration of the General L.a«s and Phenomena of Creation. By John Mason Good, M.D. F.R S. etc. 3d Edition, corrected, 3 vols, foolscap Svo. 21j. cloth. GRAH.VM.- ENGLISH; OR, THE ART OF COMPOSITION explained in a Series of Instructions and Ex:imples. By G. F. Graham. 2d Edition, revised and improved. Foolscap Svo. 7s. cloth. GRAHAM.— HELPS TO ENGLISH GRAMMAR; Or, Easy Exercises for Young Children. By <i. V. Graham, author of "English, or the Art of Composition." Foolscap Svo. illustrated with Engravings on Wood, 3s. cloth. " Well adapted for the instruction of young children, for whose use it is especially designed." GRANT (MRS., OF LAGGAN). — MEMOIR AND CORRESPONDENCE of the late Mrs. Grant, of Laggan, author of " Letters from the Mountains," " Minioirs of an American L.idy," etc. etc. Comprising Sketches of the Society and I.iterarv Characters of Edinburgh for nearly the last thirty years. Edited by her Sou, J. P. Grant, Esq. 3 vols. post Svo. with Portrait, 3I». Gd. cloth. " nith sketches enualli/ graceful," {with that of Campbell, quoted,] " of Scott and JefTery, of irordsi^orlh and Sonthev, and H ilson and Urown, and Brewster and I halmers, and the enrli) eonlribulors to Blackwood, we could have filled our limited space, without robbing these volumes of Ihrir interest, to replete are they with opinions of wen and thiui;s, and jo abundant in lojiy sentiment and sincere pi-ty." Alias. GRATTAN — THE HISTORY OF THE NETHERLANDS, Fr.ini the Invasion bv the Koinans l.> the Delgiai. Itevulution in IHJU. By T. C. Grattan, Esq. 1 vol. foolscap Svo. with Vignette Titles, Us. clotli. GRAY.— FIGURES OF MOLLUSCOUS ANIMALS, Selected from various. Auth..r». Klched for the Use of Stu.lcnls. By Mari.l Emma <iray. Vol. I. pp. m, with 7S pliitea of Figures, IL's. cloth. GRAY AND MITCHELL'S ORNITHOLOGY.— THE GENERA OF BIRDS; Coniprisiiiir Uieir Generic Chnrnetcrs, a Notice of tlie Habits of eriih (ii mis, und .-in cxICMi- sive List of Species, referred to tlieir several (Jenera. By GcorKi- liohert Crav, Ac.-i.l. Imp. Georpr. Florcnt. Soe. Corresp. Senior Assistant of tlie Zooloyieiil Ucpartnicnt, nrilish Museum ; and author of tlie " List of the Genera of Birds," etc. etc. Illustrated with 3Stl imperial 4to. Plates, by David William Mitchell, B.A. In coursr ofpublicatinn in Monthly Parts, I0«. firf. ench; each Part consisting gpnerntlii of four imperial 'juarto coloured Plates and Three plain, and ncvompanyitig Letterpress; givini; the Generic Characters, short Remarks on the Habits, and a List of Species of each Genus as complete as possible. The nncntoured Plates wilt contain the Characters of all the Genera of the varioui Sub-families, consisting of numerous details of Heads, Wings, and Feet, as the case mat/ require, for pointing out their distinguishing Characters. ♦,• The Work will not exceed lijtv Monthly Parts. No. 6 will be published on the 1st of October. GREENER.— THE GUN; Or, a Treatise on tl;p various Descriptions of Small Fire Arms. By VV. Greener, Inventor of an Improved Methodof Firintj Cannon by Percussion, etc. 8vo. with Illustrations, 155. boards. GREENER.— SCIENCE OF GUNNERY, As applied to the use and Construction of hire Arms. Dy William Greener, author of" The Gun," etc. With numerous Plates, 15s. cloth. GREENWOOD (COL.)— THE TREE-LIFTER: Or a New Method of Transplanting Trees. By Col. Geo. Greenwood. 8vo. with an IUu.s- trative Plate, 7s. cloth. GUIST.— THE WIABINOCION, From the LI-, fr r,,cli o Hcrsjest, or Red Book of Hergest, and other ancient Welsh MSS. with an English Tr,in.sl;ition and Notes. By Lady Charlotte Guest. Royal 8vo. 8j. each. Part l.-Thc Lady of the Fountain. Parts. -Peredur Ab F.vrawc ; a Tale of Chivalry. Part 3.— The Arthurian Romance of Gcr.aint, the Son of Erbin. Part 4. -The Romance of Kilhwch and Olwen. Part 5. -The Dream of Rhonabwy, and the Tale of Pwyll Prince of Dyved. GWILT.— AN ENCYCLOP/tDIA OF ARCHITECTURE; Historical, Theoretical, and Practical. Dy Joseph Gwilt, Es'i., F S A. Illustrated with upwards of lllOO Engravings on Wood, from Designs byJ.S.Gwilt. In 1 thick vol. 8vo. containing nearly 13UU closely-printed pages. ^2l.V2s.Gd. cloth. "dwitt's Encyclopadin ranhs high as a work for professional students, containing the mathematics of architecture, with copious details upon all the technicalities of the science. It is a work which no prof essed architect or builder shotild be without."— \VestiauiKlcrRc\\c\i . HALL— NEW GENERAL LARGE LIBRARY ATLAS OF FIFTY-THREE MAPS, onColumbier Paper; with the Divisions and Boundaries carefully coloured. Con- structed entirely from New Drawings, and engraved by Sidney Hall. New Kdition, thoroughly revised and corrected ; including all the Alterations rendered necessary by the recent OHicial Surveys, the New Roads on the Continent, and a careful Comparison with the authenticated Discoveries published in the latest Voyages and Travels. Folded in half. Nine Guineas, half- bound in russia ; full size of the Maps, Ten Pounds, half-bound in russia. '^ The following Maps have been re-engraved, from entirely new designs— Ireland, South Africa. Turkeu in Asia: the following have been materiall,/ improved-Switzerland, North Italy. Smith Italy, Egypt, Central Ciermany , Southern Ce'rmany, Greece, Austria, Spain, and l'ortni:,ih anew niap of China, corrected from the recent government survey of the coast from Ciutiin to Nnuhin (tn which is appended tlie Province of Canton, on an enlarged scale, iu a separate compartment) , has since been added. HALSTED— LIFE AND TIMES OF RICHARD THE THIRD, as Duke of Gloucester and King of England : in wiiicli all the Charges against him arc care- fully investigated and compared with the Statements of the Cotcmporary Authorities. By Caroline A. Halstcd, author of " The Life of Margaret Beaufort." 2 vols. Svo.with Portrait from an Original Picture in the possession of the Right Honourable Lord Stafford, never before engraved, and other Illustrations, 1/. 10s. cloth. ^•^ IVe consider Miss Halstead's work as one of the most interesting and able pieces rflmtnry which has ever been presented to the world. Theresearch which it manif'stn is jnnst ejten.tive, the arrangement clear and lucid, the style always animated and picturesijue. Maun new lii;hts are thrown on the career of Hiclmrd, many new facts elicited, and the injustice of four centuries vindicated by thisintrepid and indefatigable champion of historical truth.''' Metropolitan Magazine. HANNAM.— THE ECONOIVIY OF WASTE MANURES: A Treatise on the Nature and Use of Neglected Fertilizers. By John Har.nam. Written for the Yorkshire Agricultural Society, and published by permission of the Counsel. Fcap. ,Svo. 3s. 6rf. cloth. " ll'e consider this an invaluable treatise. It must prove nf incnlculahle benejit to that class to whum it is chiefly addressed By the i;eneral reader it will likewise be perused with no common interest. ' It is a Ineid, practical denionstralinu from bri;i„ning to end. The writer is not only entirely master of his subjecl, but he has unfolded it in the most scientific, and, ue would add, logical manner. He has displayed so marked a precision iu his e.rpositinn, that the dullest capacity may at once cnmprehendhis meaning and the diift oj his argument ." — Aiin.^ PRINTED lOR LONGMAN, UROWN, AND CO. 13 HAND-BOOK OF TASTE; Or, How to Observe Works of Art, e^pcclall}- Cartoons, Pictures, and Statues. 2d Edition. By Kabius Pictor, foolscap 8vo. 33. boards. " H> have never met vith a compendious treatise on art, and the ptiticiples whie/i should guide taste in judging of its productions, that contained moie e^cclletit matter than this small unpretending volume. It is eipressll/ compiled for the instruction of the public, and itith a view to that era in art ithich the decoration of the new Houses of Parliament, and the present display of the cartoons in n'estminsler Hall, may be expected tu create. It exhibits the opinions of the best artists and critics of all ases. It is not intended to instruct the itudent in art, though he mav profit much by its lessons, but to tell the observer how he mai) judge nf the productions of the Jine arts. It is not flattering to set out irith sni/iug that England, in the art of design, is not only immeasurably behind Itnln, hut falls short of what France aspires to, and Germany has accomplished ; but this is qualified by the admission that England is, nevertheless, quite capable of efficient progress."— Ta.iVs Magazine. HANSARD.— TROUT AND SALMON FISHING IN WALES. By G. A.Hansard, l-Jmo. 6».6rf. ciotli. HARRIS— THE HIGHLANDS OF /ETHIOPIA; Being tlie .Account of Eigliteen Jlontlis' Residence of a British Embassy to ttie Cliristian Court of Slioa. By Major W. C. Harris, author of " Wild Sports in Southern Africa," etc. 2d Edition. 3 vols! Svo. with Map and Illustrations, 21. 25. cloth. ".fir II illiam Harris has produced a work of eitraordinary interest and value ; a narrative which will take a permanent place in the library, as the best authority ever yet given to the wurld on all the subjects to which it relates. It has, moreover, for present readers, the charm of p.rf ret freshness and novelty. The wri(i">'s inquiries extend to the minutest particulars of the habits, manners, customs, political and social economy of the people, among whom he was a welcomed t/ijiior. "—Forei^cn and Colonial Review. HAWKER.-INSTRUCTIONS TO YOUNG SPORTSMEN In all that relates to Guns and Shooting. Bv Lieut. Col. P. Hawker. 9th edition, corrected, enlarged, and iuiprovod, with Eighty-five Plates and Woodcuts, by Adlard and Branston, from Drawings by C. Varley, Dicks, etc. 21». cloth. " H'e have to often spoken favourablii of preceding editions of this popular work, that we need only notice the opportune publication of the Ninth, Schick has just made its appearance, and which brings every branch of sporting, in relation to the Jitld and gun, down to the present time; giving interesting notes of whatever has been done in the way of change and improvement." — Literary Gazette. HENSLOW. — THE PRINCIPLES OF DESCRIPTIVE AND PHYSIOLO- GICAL BOTANY. Bv J. S. Henslow, M.A. F.L.S. etc. 1 vol. foolscap Svo. with Vignette Title, and nearly /(I Woodcuts, (Is. cloth. HEIISCHEL.— A TREATISE ON ASTRONOMY. By Sir John Herschcl. New Edition. 1 vol. fcap. Svo. Vignette Title, 6». cloth. HERSCHEL. — A PRELIMINARY DISCOURSE ON THE STUDY OF NATURAL PHILOSOPIiy. By Sir John Hcrschel. New Edition. 1 vol. foolscap Svo. with Vignette Title, Gj. cloth. HINTS ON ETIQUETTE AND THE USAGES OF SOCIETY: With a Glance at Bad Habits. 'By P^ytoyoq. "Manners make the Man." 23d Edition, revised (with additions) by a Lady of Rank. Foolscap Svo. 2». 6d. handsomely bound in fancy cloth, gilt edges. . o , . General Observations ; Introductions— Letters of Introduction— Marriage— Dinners— bmoking; Snuff— KiVihiou— Dress— Music— Dancing— Conversation— Adviceto Tradespeople— Visiting; Visiting Cards — Cards— Tattling— of General Society. HOARE.— A DESCRIPTIVE ACCOUNT OF A NEW METHOD OF PLANTING AND MANAGING THE ROOTS OF GRAPE VINES. By Clement Hoare, author of ".\ Treatise on the Cultivation of the Grape Vine on Open Walls." 12mo bs. cl. •,♦ The facts, proved by experiments carried on by Mr. Hoare for a series oj years, are so extraordinary, that there is every reason to believe they will effect a complete revolution in the planting of the Crape fine. HOARE— A PRACTICAL TREATISE ON THE CULTIVATION OF THE GRAPE VINE ON Ol'EN WALLS. By Cl.ninit Hoare. :i.l Edition, Svo. 75. Crf. cloth. HOBllES.— ENGLISH WORKS OF THOMAS HOBBES, Of Malnusburv; now first collected bv Sir William Molesworth, Bart. Vol.10, contain- ing the Translation of Homer's Iliad and Odyssey. Svo. IO5. cloth, to non-subseribcrs, 12s. Nine preceding Volumes have been published of the English and Latin Works. Vols. 8 and t), recently publiihed, comprise the Translation of Thucydides. HOLLAND— PROGRESSIVE EDUCATION : Or, Considerations on the Course of Life. Transl.ited from the French of Madame Necker de Sausiure. By Mi.ss lloU.inrl. 3 >ol .. foolsca|> Hvo. 1()5. firf. cloth. •,* The Third Volume, forming an appropriate conclusion to thefirst two, separately ,7s. C,d. HOLLAND— A TREATISE ON THE MANUFACTURES IN METAL. By John Holland, E»q. 3 vols. looUcap Svo. with Vignette litles, and about MU Woodeuts, l»l«. cloth. 14 CATALOGUE OF NEW WOUKS HOLLAND.— MEDICAL NOTES AND REFLECTIONS. By Henry Hollaud, M.D. F.R.S. etc. Follow of ihe Royal College of Physicians, Physician Extraordinary to the Queen, and Physician in Ordinary to His Royal HighnessPrince Albert. 2d Edition, Ivol. 8vo. pp. 654. ISj. cloth. HOOKER.— THE BRITISH FLORA. In 2 vols. Vol.1.; coraprisinj the Phajnogamous or Flowering Plants, and the Ferns. BySir William Jackson Hooker, K.H. LL.U. F.R.A. and L.S. etc. etc. etc. 5th Edition, with Additions and Corrections; and 1/3 Figures, illustrative of the Umbelliferous Plants, the Composite Plants, the Grasses, and the Ferns. Vol. I. Svo.pp. 502, with 12 Plates, 14s. plain ; with the plates coloured, 24.?. cloth. Vol. II. in Two Parts, comprising the Cryptogamia and the Fungi, completing the British Flora, and forming Vol. V., Parts 1 and 2. of Smitli's English Flora, 24j. boards. HOOKER.— ICONES PLANTARUM; Or, Figures, with brief Descriptive Characters and Remarks, of New and Rare Plants, selected fiom the Author's Herbarium. By Sir W.J. Hooker, K.H. LL.D. etc. 4vol8.Svo. with 4UL1 Plates, 5/. 12s. cloth. HOOKER AND TAYLOR.-MUSCOLOCIA BRITANNICA. Cont.iining the Mosses of Great Britain and Ireland, systematically arranged and described ; with Plates, illustrative of the character of the Genera and Species. By Sir W.J. Hooker and T.Taylor. M.D. F.L.S. etc. 2d Edition, 8vo. enlarged, 3l8. 6rf. plain ; 3/. 3l. coloured. HORSLEY (BISHOP).- BIBLICAL CRITICISM ON THE FIRST FOUR- TEEN HISTORICAL BOOKS OF THE OLD TESTAMENT; AND ON THE URST NINE PROPHETICAL BOOKS. Bv Samuel Horslev, LL.D. I'.R.S. K.A.S. Lord Bishop uf St. Asaph. Second Edition, containing Translations by the Author, never before published, together with copious Indexes. 2 vols. Svo. tHJs. cloth. HOWITT (MARY).— THE CHILD'S PICTURE AND VERSE BOOK, Commonlv called " Otto Speckter's Fable Book." Translated by Mary Howitt. With French and German on corresponding pages, and illustrated with ICiO Engravings on Wood, by G. F. Sargent. Square 12mo. 10s. Gfi. boards. " Otto Speckter's illu$lTations are well ciilculnted to please children ; some hy their truth, others by their humour. The verses, tun, are in ii kindly spirit—some sly-some chiming in those cu,al-and bells measures which ouf;ht never to he out of the ear of such as write Jor the very young- Mrs. Howitt has, in naturalising this book, done a good deed with a good grace.'' AthenaMim. HOWITT (MARY).— THE H FAMILY: TRALINNAN ; AXEL AND ANNA ; and other Talcs. By Fredrika Bremer. Translated by Maiy Howitt. 2 vols, post Svo. with Portrait of the Author, 21s. boards. " One great charm of Fredrika Bremer is her quiet icay of doing every thing. Whethrr she soars into the mysticism of German metaphysics, or gives the gossip of the tca-tuble- ,rhether she utters the most biting sarcasm, or gives expression to the kindlieit feeling, it is nil done without the least appearanc of effort. This elegant repose pervades her story of th- ' U Family,' and makes us like it in some respects better than any other of her writing's." John Bull. THE PRESIDENT'S DAUGHTERS, includ- ing NINA. By Fredrika Bremer. Translated by Mary Howitt. 3 vols, post Svo. 31s. Iirf. THE NEIGHBOURS. A Story of Everyday Life in Sweden. By Fredrika Bremer. Translated bv Marv Howitt. 3d Edition, revised and corrected, 2 vols, post Svo. l.Ss. THE HOME ; or. Family Cares and Family Joys. By Fredrika Bremer. Translated by Mary Howitt. 2d Edition. 2 vols, post Svo A NEW SKETCH OF EVERY-DAY LIFE : A DIARY. Together with STRIFE ai PEACE. By Fredrika Bremer. Translate 2^' ' I bv M.ary Howitt. 2 vols, post Svo. 21s. HOWITT.— THE RURAL LIFE OF ENGLAND. Bv William Howitt. Third Edition, corrected and revised, medium Svo. with Engravings Wood by Bewick and Williams, uniform with " Visits to Remarkable Places," 21s. cloth. Life of the Aristot Life of the Agricultural Population. Picturesque and Moral Features of the Country. Strong Attachment of the English to Country Life. The Forests of England. Habits, Amusements, and Condition of the People; in which are introduced Two New Chapters, descriptive of the Rural Watering Places, and Education of Rural Population. HOWITT.— VISITS TO REMARKABLE PLACES; Old Halls, Battle-Fields, and Scenes illustrative of Striking Passages in English History and Poetry. By William Howitt. New Edition, medium Svo. with 4U Illustrations by S. Willian.s, SECOND SERIES, chiefly in the Counties of DURHAM and NORTHUMBERLAND, with a Stroll along the BORDER. 1 vol. medium Svo. with upwards of 40 highly-finished Woodcuts, from Drawings made on the spot for this Work, by Alessrs. Carmichael, Richardsons, and WeldTaylor, 21s. cloth. IIOWITT.-THE LIFE AND ADVENTURES OF JACK OF THE MILL, Commonly called " Lord Othmill ;" created, for his eminent services. Baron Waldeck, ao.l Knight of Kitcottie; a Fireside Story. By William Howitt. 2 vols, foolscap Svo. with 4(1 Illustrations on Wood by G. F. Sargent, 15s. cloth. *' This agreeable story will be a great favourite uith a large class of juvenile readers, and will sustain the unwearied interest even of those who hare passed the season of youth. The stvle is racy, animated, and sparkling; the story never Jiags, and its moral bearing is mi, si e/ctHfn«."— Eclectic Review. PRINTED FOR LONGMAN, BROWN, AND CO. 15 HOWITT-THE RURAL AND SOCIAL LIFE OF GERMANY: With Characteristic Sketches of its chief Cities and Scenery. Collected in a General Tour, and durine a Residence in that Country in the Years lS40-4i. Bv William Howitt, author of "The Rural Life of Eugland," "Visits to Remarkable Places," "The Boy's Country Book," etc. 1 vol. mediuiu Sro., with above 50 Illustrations, 21». cloth. " IFe cordially record our conviction of the value of Mr. Hatcitfs volume, and strongly leco'iimeud its early perusal. It is both instructive and entertaining, and will be found to familiarize the English reader with farms of character and modes oj social life, vattly dijfer- ent from anything witnessed at home."— EclticUC Review. HOWITT.— GERMAN EXPERIENCES: Addressed to the English, both Goers Abroad and Stayers at Home. By ^V^Uiam Howitt. Foolscap Svo. "/s. 6d. cloth. " The minute practical information given in this book respecting Germany, and the modes of living there, will be found of great use to the English resident, who. for the purpose of educa- tion or economy, sets up his tent in that country. It is a book full of facia-factt of direct utility to the travelling English "—Court Journal. HOWITT.— WANDERINGS OF A JOURNEYMAN TAILOR, through EUROPE and the EAST, during the vears 1824 to 1S40. Bv P. D. Holthaus, from Werdohl in Westphiilia. Translated from the Third German Edition, by William Howitl, author of "The Rural and Social Life of Germany," etc. etc. Foolscap Svo. with Portrait of the Tailor, 6j. cloth. HOWITT —THE STUDENT-LIFE OF GERMANY. From the Unpublished MS. of Dr. Cornelius. By William Howitt. Svo. with 24 Wood- Eugravings, and 7 Steel Plates, tls. cloth. " German student-life has, of course, its brighter side and pleasanter traits. Its generous friendships, its buoyant spirits, its noble songs, its intense study, at the list may well com- pensate for many of its darker features. In this volume there is no want of material to form a very sufficient notion of German jfurf<?n(-7i/e."— Quarterly Review. HOWITT.-COLONIZATION AND CHRISTIANITY: A Popular History of the Treatment of the Natives, in all their Colonics, by the Europeans. By William Howitt. 1 vol. post Svo. 10». 6d. cloth. HOWITT.— THE BOY'S COUNTRY BOOK: Being the real Life of a Country* Bov, written by Himself; exhibiting all the Amusements, Pleasures, and Pursuits of Children'in the Country. Edited by William Howitt, author of " The Rural Life of England," etc. 2d Edition, fcap. Svo. with 40 Woodcuts, S». cloth. "yl capital work, and, we are inclined to think, Howitt'sbest inany /ine."— Quarterly Review. HUDSON.— THE PARENT'S HAND-BOOK; Or, Guide to the Choice of Professions, Employments, and Situations , containing useful and practical information on the subject of placing out Young Men, and of obtaining their Education with a view to particular occupations. By J. C. Hudson, Esq., author of " Plain Directions for Making Wills." Fcap. Svo. bs. cloth. " This volume will be found useful to any parent who is painfully meditating upon that difficult subject, how and where he can best place his sons in the morW."— Spectator. HUDSON.-PLAIN DIRECTIONS FOR MAKING WILLS In Conformity with the Law, and particularly with reference to the Act 7 Win. IV. and 1 Vict, c. 26. To which is added, a clear Exposition of the Law relating to the Distribution of Per- sonal Estate in the case of Intestacy ; with two Forms of Wills, and much useful Information, etc. By J. C. Hudson, of the Legacy Duty Office. 12th Edition, corrected, with Notes of Cases judicially decided since the above Act came into operation. Fcap. Svo. 2s. 6(/. HUDSON.-THE EXECUTOR'S GUIDE. By J. C. Hudson. 3d Edition, foolscap Svo. 5». cloth. *.* The above two works may be had in 1 volume, priceTt. cloth. HUMPHREYS.— THE ILLUMINATED BOOKS OF THE MIDDLE ACES. A History of Illuminated Books, from the IVth to the XVlIth Century. By Henry N"cl Humphreys. Illustrated by a Series of Specimens, consisting of an entire I'agc, of the exact size of the Original, from the most celebrated and splendid MSS. in the Imptrial and Royal Libraries of Vienna, Moscow, Paris, Naples, Copeuhacen, and Madrid ;_from the Vatican, Escurial, Ambrosian, and other great Libraries of the Continent ;— and from the rich Public, Collegiate, and Private Libraries of Great Britain; superbly printed in Gold, Silver, and Colours. In course of publication, in Parts, issued at intervals of about two months ; each Part to con- tain Three Plates, of the exact size of the original subjects, and each Plate accompanied by a description, with some account of the MS. from which it is taken. The last Part to contain an Historical Sketch of the Progress of the Art of Ulumiuation, with a Table for placing the Plates in Chronological Order. Each Part, containing Three Plates, with Descriptions, Imperial Quarto (15 in. by II), splendidly printed, ill gold, silver, and colours, iu imitation of the originaU, as accurate as can be produced bv mechanical means, price 12». Large Paper, on Half Imperial {21* in. by 15), to prevent folding the large Plates, 21». Six Parts to form a Volume, Four Volumes completing the work " We have seen some specimens of a proposed work by Mr. Ilumuhreys, on Illuminated M.'<.'>. which hare surprised «, by the accuracy of tktir est cation, and the effect produced by merely mechanical means.- (Juarlcrly Ruiew. 16 CATALOGUE OF NEW WORKS HUNT.-RESEARCHES ON LIGHT: An Examination iif nil tin- Phenomena connected with the Chemical nnd Molecular Chanpts produced by the Influence of the Solar Rays ; embracing- all the known Photograjihic I'lu- ccsses, and new Discoveries in the Art. Bv Robert Hunt, Secretary of the Royal Cornwall Polytechnic Society. Svo. with Plate and Woodcuts, lUs. 6rf. cloth. " Mr. Hunt's reputation it so melt established, that we need only mention hit pleasing volume to secure it a favourable reception from the philosophical public.'^ Jameson's New Edinburgh Philosophical Journal. HUNTER. -THE RISE OF THE OLD DISSENT, Kxemplified in the I.ifc of Oliver Ilevwood : Kith a Sketch of the subsequent History of the English Prssbytcrian Dissenters. By the Rev. Joseph Hunter, F.S.A. Svo. 7». cloth. JACKSON —PICTORIAL FLORA ; Or, British Botany Delineated, in 1500 Lithographic Drawings of all the Species of Floweriui; Plants indigenous' to Great Britain : illustrating the descriptive works on English Botany of Hooker, Lindley, Smith, etc. By Miss Jackson. Svo. 15s. cloth. JAMES.— A HISTORY OF THE LIFE OF EDWARD THE BLACK PRINCE, and of various Events connected therewith, whicii occurred during the Reign of Edward 111. King of England. By G. P. R. James, Esq. 2d Edition, 2 vols, foolscap Svo. with Map, 1.5s. cloth. JAMES.— LIVES OF THE MOST EMINENT FOREIGN STATESMEN. BvG.P. R. James, Esq., and E.E. Crowe, Esq. 5 vols. foolscaD Svo. with Vignette Titles. 3b». cloth. LORD JEFFREY.-CONTRIBUTIONS TO THE EDINBURGH REVIEW. By Franci8 JeCfrey, now one of the Judges in the Court of Session in Scotland. 4 vols. Svo. 48s. cloth. JOHNSON.- THE FARMER'S ENCYCLOP/EDIA, And DICTIONARY of RURAL AFFAIRS: embracing all the recent Discoveries in Agri- cultural Chemistry; adapted to the comprehension of unscientific Readers. By Cuthbert W. Johnson, Esq., F.R.S. Barrister-at-Law, Corresponding Member of the Agricultural Society of Konigsberg, and of the Maryland Horticultural Society , Author of several of the Prize Essays of the Royal Agricultural Society of England, and other Agricultural Works ; Editor of the ** Farmer's Almanack," etc. 1 thick vol. Svo. illustrated by Wood Engravings of the best and most improved Agricultural Implements. 2/. 10s. cloth. ** Cuthbert Johnson's * Farmer's Encyclopadia' is one of the best books of its class'* Dr. Lindley, in The Gardener's Chronicle. KANE. -THE INDUSTRIAL RESOURCES OF IRELAND. Bv Robert Kane, M.D. Secretary to the Council of the Roval Irish Academy, Professor of Natural Philosophy to the Royal Dublin Society, and of Chemistry to the'Apothecarics' Hall of Ireland. Post Svo. "s cloth. *' We have been much struck by a work recently published, by Professor Kane, on the * Industrial Resources of Ireland.' The volume contains a masterly view of the physical materials upon which Irish industry might work. The fuel, the water-power, the minerals, the composition and capabilities of the soil, the nature and locality of manures, and the means of internal covimunication ejristing in the country, are successively taken up, analysed, and laid before the reader, iu their scientijic as well as their practical bearings. Nothing can leave a stronger impression of the mismanagement from which Ireland has suffered than Dr. Kane's clear and business-like statement of the demerits of wealth and power which have so long lain almost idle in her possession." — Morning Chronicle. KANE.— ELEMENTS OF CHEMISTRY; Including the most Recent Discoveries and Applications of the Science to Medicine and Pharmacy, and to the Arts. By Robert Kane, M.D. M.R.I. A. Professor of Natural Philosophy to the Royal Dublin Society. Svo. with 236 Woodcuts, 24«. cloth. KATER AND LARDNER.— A TREATISE ON MECHANICS. By Captaiu Kater and Dr. Lardner. New Edition. 1 vol. foolscap Svo. Vignette Title, and lii Plates, comprising 224 distinct figures, 6s. cloth. KEIGHTLEY. -OUTLINES OF HISTORY, From the Earliest Period, By Thomas Keightley, Ksq. New Edition, corrected and con- siderably improved, foolscap Svo. pp. 468, 6*. cloth ; or 65. f>d. bound. KING —A SELECTION FROIVI THE SPEECHES AND WRITINGS OF THE LATE LORD KING. With a short Introductory Memoir, by Earl Fortcsque. Demy Svo, Portrait, 12s. cloth. *' Earl Fortescue has rendered good service to both economic and moral science by this seasonable publication. His selections are most judiciously made, and will raise his relative's high character as an able and iipright politician^ whose vievs were singularly in advance 0/ his a^e, white evert/ parliametttary session adds proof of their soundness. In ?iis Memoir, his Lordship has shcvn that he can not only appreciate Lord Kintr, but that he is well able to inaintai?! the principles and enforce the doctrines to which his illustrious relative devoted his /i/r."— Athenaeum. KIPPIS.— A COLLECTION OF HYMNS AND PSALMS, For Public and Private Worship. Selected and prepared by A. Keppis, D.D., Abraham Rees, I>.D., the Rev. Thomas Jervis, and the Rev, T. Morgan. To which is added, a Supplement. New Edition, corrected and improved, 18nio. bs. bound. PRINTED FOR LONGMAN, BROWN, AND CO. 17 KIRBY AND SPENCE.— AN INTRODUCTION TO ENTOMOLOGY; Or, Elenicats of the Natural History of Insects: com|)risinf an account of noxious and useful Insects, of their Mctamor|)hoses, Food, Stratagems, Habitations, Societies, Motions, Noises, Hybernation, Instinct, etc. Bv VV. Kirby, M.A. F.R.S. & L.S. Rector of Barham ; and \V. Spence, Esq., F.R.S. S: L.S. '6th Edition, corrected and considerably enlarged, 2 vols. Svo. 11. n». 6rf. cloth. The Jirst two volumes of the ^' Introduction to Entomoln^y" arc now puhVtthed n> a separate tcorh, distinct from the third and fourth volumes, and, though much enlarged, at a considerable reductitm of price, in order that the numerous class oj readers who confine their study of insects to thai of their manners and economy, need not lie burthened with the cost of the technical portion oj the work relating to their anatomy , physiology , etc, KNAPP.— CRAMINA BRITANNICA; Or, Representiitions of the British Grasses: with Remarks and occasional Descriptions. By I. L. Knapp, Esq. F.L.S. & A.S. 2d Edition, 4to. with IIS Plates, beautifully coloured, 3/. ICs. boards. ** ^fost of th-" persons interested in the art of distinguishing grasses are country gentlemen and farmers, who know nothini; of botiini/, and cannot use the tecninal descriptions or analy- tical figures of botanists. To that great class such a booh is invaluuhle. It ought, in fact, to form part of the library of every one interested in rural a/fairs : for Ihrre are few plants so difficult to distinguish as grasses, not any more lo, and none n-hiih it is more important to know eorrectli), because of their various uses and qualities. IVith Mr. Kuupp's book before him, tio one can have the least difficulty in making himself master of the subject.'''' Gardeners' Chronicle. LAING, (S., JUN.)-NATIONAL DISTRESS: Its Causes and Remedies. Bv Samuel LainK, J"n., Esq., late Fellow of St. John's College Cambridge. Svo. 7s. 6<i cloth'. •,' The Essay to which the First I'rixe of U)0!., offered by The AiUs newspaper, was awarded. LAING.— THE CHRONICLE OF THE KINGS OF NORWAY, From the Earliest Period of the History of the Northern Sea Kinijs to the Middle of the Twelfth Century, commonly called the Heimskringla. Tran.slated from the Icelandic of Snorro Sturleson, with Notes, and a Preliminary Discourse, by Samuel Laing, author of "Notesof aTravellcr,"etc. 3 vols. Svo. 3fis. cloth. •*>Ve have been rather profuse i7i our e:rtracts from this curious and most characteristic old histori/. But it is long since we have met with a work so spirited, and so ntintsing, and at the same time afordiug such valuable infiirmatiou respecting a race to whom we are so largely indebeld, as this venerable Chronicle of Snorro A^Kr/esoH."- Eclectic Review. LAING.— A TOUR IN SWEDEN In 1m;jS; comprising Observations on the Moral, Political, and Economical State of the Swedish Nation. By Samuel Laing, Esq. Svo. I2s. cloth. LAING.— NOTES OF A TRAVELLER On the Social and Political State of France, Prussia, Switzerland, Italy, and other parts of Europe, during the present Century. By Samuel Laing, Esq. 2d Edition, Svo. ICs. cloth. LAING.— JOURNAL OF A RESIDENCE IN NORWAY During the years 1S34, 1S35, and 183G; made with a view to ini|uire into the Rural and Political Economy of that Country, and the Condition of its Inhabitants. By Samuel Lain;;, Esq. 2d Edition, Svo. I4s. cloth. LARDNER'S CABINET CYCLOP/EDIA; Comprising' a Series of Original Works on History, Biography, Literature, the Sciences, Arts, and Manutactures. Conducted and edited by Dr. Lardner. The Series complete in One Hundred and Thirty-three Volumes, 39/. 18». (One Volume remains to be published.) The Works separate, fi«. per volume. " In the completeness of its treatises the Cabinet Cyclopa:dia is unrivalled; and now that the vhole plan is carried out, it cihibits an CTtensive body of available knowledge, such as this or po '.ther country has everyil presentedin a popular and convenient form."— Britannia. LARDNER.— A TREATISE ON ARITHMETIC. By Dr. Lardner, LL.I>. F.R.S. 1 vol. foolscap .Svo. with Vignette Title, r,s. cloth lettered. LARDNER AND WALKER.— A MANUAL ON ELECTRICITY, MAG- NETISM, and METKOUOLO(;y. By Dr. Lardner, LL.l). I'.K.S., and C. V. Walker, Secretar)' of the Eleclrical Society. 2 vols, foolscap Svo. \2s. LARDNER.— A TREATISE ON GEOMETRY, And its Appliciitiorj to the Arts. By Dr. Lardner. 1 vid. foolscap Svo. Vignette Title , and upwards of 2(KJ figures, il«. cloth. LARDNER.— A TREATISE ON HEAT. By Dr. Lar.lner, LL.D. etc. 1 vol. fcap. Mvo. with Woodcuts an<l Vignette Till, , (l.». cloth. LARDNER— A TREATISE ON HYDROSTATICS AND PNEUMATICS. By Dr. Lardner. New Edition. 1 vol. foolscap Svo. C«. cloth. LECTURES ON POLARISED LIGHT, Delivered by Dr. Pereirn, before thn Pliarnincculical Society, and in the Medical School of the London Hospital. Svo, illustrated by above 50 Woodcuts, &«.6f/. cluili. CATALOGUE OF NEW WORKS L. E. L.— THE POETICAL WORK OF LETITIA ELIZABETH LANDON. New Edition, 4 vols, foolscap 8vo. with Illustrations by Howard, etc. 28». cloth lettered; or handsomely bound in morocco, with gilt edges, 21. As. The following may be had separately: — THE IMPROVI.SATRICK - -Uls.iid. | THK GOLDKN VIOLET - - - lOs. firf. THE VENETIAN BRACELET lUs. Grf. 1 THE TROUBADOUR . - - . lUs. Cd. LEE.— TAXIDERMY; Or, tlie Art of Collecting. Preparing, and Mounting Objects of Natural History. For the use of Museums and Travellers. By Mrs. K. Lee (formerly Mrs. T. E. Bowdich) , author of "Memoirs nf Cuvier," etc. 6th Edition, improved, with an account of a Visit to Walton Hall, and Mr. VVaterton's method of Preserving Animals. Fcap. 8vo. with Wood Engravings, 7». cloth. LEE -ELEMENTS OF NATURAL HISTORY, For the Use of Schools and Young Persons: comprising the Principles of Classification, iiUerspeiscd with amusim^and instructive original Accountsof the most rcmarkahle Animals. BvMrs. R Lee (formerly Mrs. T. E. Buwdich), author of "Taxidermr," "Memoirs of Ciivicr," etc. limo. with ho Woodcuts, 7s. 6d. bound. LIFE OF A TRAVELLING PHYSICIAN, From his first Introduction to Practice ; including Twenty Years' V the greater part of Europe. 3 vols, post Svo. with coloured Frontispie ** There is much nmuseinent and ijifurmntiou to be gained from these pleasant and enter- tainiiig yo/Kinfs,"— Dublin University .Magazine. LINDLEY.— INTRODUCTION TO BOTANY. By Prof.J. Lindlev.Ph.D. F.R S. L.S. etc. 3d Edition (1830), with Corrections and consider- able Additions, 1 large vol. Svo. pp. CUli, with Six Plates and numerous Woodcuts, 18«. cloth. LINDLEY— FLORA MEDICA ; A Botanical Account of all the most important Plants used in Medicine, in ditTerent Parts of the World. By John Lindlcy, Ph.D. F.R.S. etc. 1 vol. Svo. ISs. cloth. LINDLEY.— A SYNOPSIS OF THE BRITISH FLORA, Arranged according to the Natural Orders. By Professor John Lindley, Ph. U,, F.R.S, etc. The 3d Edilion, with numerous Additions, Corrections, and Improvements, liiuo. pp. 390, Uls.iid. cloth. LINDLEY.— THE THEORY OF HORTICULTURE; Or, an Attempt to Explain the Principal Operations of Gardening upon Physiological Prin- ciples. By John Lindley, Ph.D. K.R.S. 1 vol. 8vo. with Illustrations on Wood. lis. cloth. This book is written in the hope of providing the intelligent gardener, and the scientific amateur, correctly, with the rationalia of the more importnnt operations of Ilortienltnre ; and the author has endeavoured to present to his readers an intelligible ej.-pl,in,ilion. founded upon well ascertained farts, which they can judge of by their own menus of ohsermition, of the general nature of vegetable actions, and of the causes nhich. while they runtrol the powers of life in plants, are capable of being regulated by themselves. The possession of such knowledge will necessarily teach them how to improve their methods oj cultivation, and leadthem to the discovery of new and better modes. LINDLEY.— AN OUTLINE OF THE FIRST PRINCIPLES OF HORTICULTURE. By Professor Lindley. ISmo. 'Zs. sewed. LINDLEY.— GUIDE TO THE ORCHARD AND KITCHEN GARDEN; Or, an Account of the most valuable Fruits and Vegetables cultivated in Great Britain : with Kalendars of the Work reriuired in the Orchard and Kitchen Garden during every month in the year. By George Lindley, CM. H.S. Edited by Professor Lindley. 1 large vol. Svo. IGs. boards. LLOYD.— A TREATISE ON LIGHT AND VISION. By the Rev. H. Lloyd, M.A., Fellow ofTrin. Coll. Dublin. Svo. 15j. boards. LORIMER. -LETTERS TO A YOUNG MASTER MARINER, On some Subjects connected wth his Calling. By Charles Lorimer. 3d edition, 12mo. with an Appendix, 5*. 6d. cloth. LOUDON (MRS.)— THE LADY'S COUNTRY COMPANION; Or, How to Enjoy a Country Life Rationally. By Mrs. Loudon, author of "Gardening for Ladies," etc. Contents- Introduction -The House — The Garden - Domestic Animals-Rural Walks- Miscellaneous Country .\museineiits -Country Duties.— /n the press. LOUDON.— AN ENCYCLOP/EDIA OF TREES AND SHRUBS; Being the " Arhoretum et Fruticetum Britannicum" abridged : containing the Hardy Trees and Shrubs of Great Britain, Native and Foreign, scientifically and popularly described : with theirPrnpagation, Culture, and Uses in the Arts; and with Engravings of nearly all the Species. For the use of Nurserymen, Gardeners, and Foresters. ByJ.C. Loudon, F. L.S. etc. In Svo. pp. 1-234. with upwards of 2000 Engravings on Wood, 2/. lll.«. cloth. The Original Work maybe had in 8 vols. Svo. with above 400 Svo. Plates of Trees, and upwards of 2500 Woodcuts, lOJ. cloth. PRINTED FOR LONGMAN, BROWN, AND CO. 19 LOUDON.— AN ENCYCLOP/EDIA OF GARDENING: PrL-seiitinir in one systematic view, the Histon- anil Present State of Gardening- in all Coun- tries, and its Theorv and Practice in Great Britain: with the Rlanasemerjt of the Kitchen Garden, the Flower Garden, Lavinij-out Grounds, etc. Bv J. C. Lnudon, F.L.S. etc. Anew Edition, enlarged and much improved, 1 larife vol. 8vo. with nearly 1000 Knc'ravings on Wood, 2/. lOs.'clotb. LOUDON.— AN ENCYCLOP/EDIA OF AGRICULTURE; Comprising the Theory and Practice of the Valuation, Transfer, Laying-out, Improvement, and Alanagement of Landed Property, and of the cultivation and economy of the Animal and Vegetable productions of Agriculture, including all the latest improvements; a general History of Agriculture in all countries; a Statistical view of its present state, with suggestions for its future progress in the British Isles; and Supplements, bringing down the work to the year 1S44. By J. C. Loudon, F.L.G.Z. and H.S. etc. Fifth Edition, illustrated with upwards of'llOO Engravings on Wood, bv Branston. 2/. lOj. cloth. The Supplement, bringing down Improvements in the art of Field-Culture from 1831 to 1844 inclusive, comprising aXl the previous Supplements, and illustrated with 65 Engravings ou Wood, mav be had sfparntely, hs. sewed. " To know that this Supplement is hy thf author of the jtistla popular Eria/clopadias of Agriculture aud Gardeniyigy is a siijficieJit recounnejidatiou for its general ea'celUiice. lude- peiideutli^ of Mr. Loudon's lonsr practical ej'perievce^ every nvailal'le authority on af^ricnlturCf and wurhs on other sciences in connexion with it, have been consulted, and the result is, one of the most valuable works on rural affairs either in our own or in anu other lanyiia^e.*' British Farmer's Magazine. LOUDON.— AN ENCYCLOP/EDIA OF PLANTS; Including all the Plants which are now found in, or have been introduced into. Great Britain; giving their Natural History, accompanied by such Descriptions, Engraved Figures, and Elementary Details, as may enable a beginnerj who is a mere English reader, to discover the name of every Plant which he may find in flower, and acquire all the information respecting it which is useful and interesting^ The Specific Characters by an Eminent Botanist ; the Drawings by J. D. C. Sowerby, F.L.S. A new Edition (1841), with a new Supplement, com- prising every desirable particular respecting all the Plants originated in, or introduced into, Britain between the first publication of the work, in 1829, and January 1840: with a new General Index to the whole work. Edited by J. C. Loudon, prepared bv W. H. Baxter, Jun., and revised by George Don, F.L.S. ; and 800 ne\v Figures of Plants, on Wood, from Drawings by J. D. C. Sowerby, F.L.S. One very large vol. 8vo. with nearly lU.OUOWood Engravings, 31. 13». 6rf. *.• The last Supplement, separately, 8vo. pp. 190, los. cloth. LOUDON.— AN ENCYCLOP/EDIA OF COTTAGE, FARM, AND VILLA ARCHITECTURE and FIRXITURE. Containing Designs for Cottages, Villas, Farm Houses, Farmeries, Country Inns, Public Houses, Parochial Schools, etc. ; with the requisite Fittint'S-up, Fixtures, and Furniture, and appropriate Offices, Gardens, and Garden Scenery : each Design accompanied by Analytical and Critical Remarks illustrative of the Principles of Architectural Science and Taste on which it is composed, and General Estimates of the Expense. ByJ. C.Loudon, F.L.S. etc. New Edition (1842) , corrected, with a Supplement containing 160 additional pages of letter-press, and nearly 300 new engravings, bringing down the work to 1842. 1 very thick vol. 8vo.,with more than 2000 Engravings on Wood, 63». cloth. " The late Mr. Loudon has the merit of having conveyed more information upon archi- tecture in a popular style, as adapted for general readers, than was ever attempted before, or than has beeii accomplished since . His Enci/cloptedia of Cottat^e and Village Architecture is indispensable to the library of all non-professional readers who may at some time of their life propose to build a cottage or country-house.^' — Westminster Review. *,* The Supplement, «fp«r«(??y,8vo.7«. 6rf. sewed. LOUDON.— HORTUS BRITANNICUS: A Catalouue of all the Plants indigenous to or introduced into Britain. Tlie 3d Edition (1832), with a New Supplement, prepared, under the direction of J. C. Loudon, by W. H. Baxter, and revised by George Don, F.L.S. 8vo. BU.firf. cloth. The Supplement (183.'i) separately, Svo. 2s. 6rf. sewed. The later Supplement (1839) separately, Svo. 8». sewed. LOUDON— THE SUBURBAN GARDENER AND VILLA COMPANION: Comprising the Choice of a Villa or Suburban Residence, or of a situation on wliich to form one; the Arrangement and Furnishing of the House; and the Laying-out, Planting, and general Management of the (iarden and Grounds ; the whole adaptect for grounds from one nerch to fifty acres and upwards in extent; intended for the instruction of those who know little of Gartfening or Rural AfTairs, and more particularly for the use of Ladies. liyJ.C. Loudon, F.L.S., etc. 1 vol Svo. with above 3U0 Wood Engravings, 20«. cloth. LOUDON. -HORTUS LICNOSUS LONDINENSIS ; Or, H Catalogue of all the Ligncciu>> Plants cultivated in the neighbourhood of London. To which are added their usual Prices in Nurseries. ByJ.C. Loudon, F.L.S. etc. Svo. 7s. Gd. LOUDON.-ON THE LAYING-OUT, PLANTING, AND MANAGEMENT OF CE.METF.RIES ; and on the Improvement of Churchyards. By J. C, l.ou.l.ui, F.L.S., etc. Svo. with GO Engravings, 12». cloth. LOW. -ON LANDED PROPERTY, AND THE MANAGEMENT OF ESTATES; Comprehending the Hclati. ins between Landlord and Tenant, an. I tlie I'l ini ipl. s a. .1 Furrns of Leasej; the Construction of Farm buildings, Enclosurck, Drains, Eml>ankments, and other Works j and the Economy of Woods, Mines, etc. By David Low, F K.S.E. etc , Hvo. Jn the press. 20 CATALOGUE OF NEW WORKS LOW. — THE BREEDS OF THE DOMESTICATED ANIMALS OF GREAT BRITAIN described. By David Low, Esq. F.R.S.E., Professor of Affriculturc in the Univer- sity of Edinburgh ; Memberof the Roval Academy of Agriculture of Sweden; Corresponding Member of the Conseil Royal d'Agriculture de France, of the Societe Roval tt Centrale, etc. etc. The Plates from drawings by W. Nicholson, R.S.A., reduced from a Series of Oil Paintings, executed for the Agricultural Museum of the University of Edinburgh by W. Shiels, R.S.A. In 2 vols, atlas quarto, with 56 [ilates of animals, beautifully coloured after Nature, 16^ I69. half-bound in morocco. Or in four separate portions, as follow : — The OX, in 1 vol. atlas quarto, with 22 Plates, I The HORSE, in 1 vol, atlas quarto, with 8 price Rt. Ifis. M. half-bound morocco. Plates, price 3/. half-bound morocco. The SHEEP, in 1 vol. atlas quarto, with 21 The HOG, in 1 vol. atlas quarto, with 5 Plates, Plates, price 6?. 16s. 6rf. half-bound morocco. I price 21. 2». half-bound morocco. LOW.— ELEMENTS OF PRACTICAL AGRICULTURE; Comprehending the Cultivation of Plants, the Husbandry of the Domestic Animals, and the Economy of the Farm. By David Low, Esq. F.R.S.E., Professor of Agriculture in the Uni- versity of Edinburgh. 8vo. 4th Edition, with Alterations and Additions, and above 200 Wood- cuts, 21». cloth. *^ Low's ^Elements of Practical Agriculture^ is the best work on farming t7i ojir lavgnage.^'' Gardeners' Chronicle. MACAULAY. -CRITICAL AND HISTORICAL ESSAYS CONTRIBUTED TO the EDINBURGH REVIEW. By the Right Hon. Thomas Babington Macaulay. 3dEdition, 3 vols. 8vo.3fis. cloth. MACAULAY. -LAYS OF ANCIENT ROME. By T. B. Macaulay, Esq. 5th Edition, crown Svo. pp. 192, 10s. Gd. cloth. MACKENZIE.— THE PHYSIOLOGY OF VISION. By W. Mackenzie, M.D., Lecturer on the Eye in the University of Glasgow. Svo. with Woodcuts, Uls. 6d. boards. MACKINTOSH'S (SIR JAMES) MISCELLANEOUS WORKS; Including his Contributions to the Edinburgh Review. Collected and Edited by his Son. 3 vols. Svo. — In the press. MACKINTOSH, ETC.— THE HISTORY OF ENGLAND. By Sir James Mackintosh ; W. Wallace, Esq. ; and Robert Bell, Esq. 10 vols, foolscap Svo. with Vignette Titles, 3(. cloth. MACLEOD.— ON RHEUMATISM, And on the Affections of the Internal Organs, more especially the Heart and Brain, to which it gives rise. By R. Maclcod, M.D. Physician to St. George's Hospital. 1 vol. Svo. pp. 1/2, 7s. cloth. M'CULLOCH.— A DICTIONARY, GEOGRAPHICAL, STATISTICAL, AND HISTORICAL, of the v.irious Countries, Places, and Principal Natural Objects in the World. ByJ.R.M'CuUoch, Esq. 2 thick vols. Svo. illustrated with Six large important Maps, 4/. cloth. " The ea-tent uf information this Dictionary affords on the subjects referred to in its title is trull) surprising. It cannot fail to prone a vade meciim to the student, whose inquiries will be guided by its light, and satisfied by its clear and frequently elaborated communications. Evert) public room in which commerce, politics, or literature forms the subject of discussion, ought to be furnished with these volumes."— (Mohe. M'CULLOCH.— A DICTIONARY, PRACTICAL, THEORETICAL, AND HISTORICAL, OF COMMERCE, AND COMMERCIAL NAVIGATION. By J. R. M'Culloch, Esq. An entirely New Edition (1844), 8vo., illustrated with Maps and Plans, 50». cloth; or 55». strongly half-bound in Russia, with flexible back. " Without eraggeration one of the most wonderful compilations of the age. The power of continuous labour, the wide range of inquiry, and the power of artistical finish, which have been brought into play by this work, are probably unrivalled in the history of literature . . Compared with all previous attempts to compile a commercial dictionary, Mr. M'Cnlloch's appears as the realisation of an idea which former projectors had conceived too vaguely to be able to carry into execution. It is superior to them all, quite as much J or the spirit of judirious selection brought by the author to his task, as for any other quality. The great merit of the work is, that, while omitting nothing of essential importance, it contains nothing that is useless or merely cumbrous . . . The success of the earlier editions of Mr. M'Cnlloch's Dictionary is, after all, the best proof of its merit; the facts attending it prove that the mercautile, political, and literary public were in want of such a work, and that they were satisfied with the manner in which Mr. M'Culloch had performed his task. Ao readfr can rise from the perusal of any one of the larger articles without feeling that no previous writer has concentrated so much valuable information within so small acompnss, or conveyed his inform- ation in so agreeable a style. And the remark is equally applicable to all the numerous articles of which this crammed volume is composed .... It is, indeed, invaluable as a book of reference to the merchant, the insurance-agent, the statesman, and the journalist ; audits articles, from the care and talent with which they are eirecuted, are as well calculated to supply the wants of the patient inquirer as of the hurried man of business. Mr. M'( nlloch occupies a high place amongst the authors of the day as a hard-headed original thinker in political economy: a still higher, as one of the most zealous and successful labourers in rendering that science popular ; but, of all his publications, his Commercial Dictionary is the one least likely to encounter the rivalry of a work of superior or even equal value." Abridged fr07n The Spectator of March 16, 1844, PRINTED FOR LONGMAN, BIIOWN, AND CO. 21 M'CULLOCH.— THE PRINCIPLES OF POLITICAL ECONOMY: With some Enquiries respecting tlieir Application, and a Sketch of the Rise and Progress of the Science. By J. R. M'Culloch, Esq. New Edition, enlarged and corrected throughout, 8vo. 15». cloth. MALTE-BRUN.— A SYSTEM OF UNIVERSAL GEOGRAPHY, Founded on the Works of Malte-Brun and Balbi, embracing an Historical Sketch of the Progress of Geographical Discovery, the Principles of Mathematical and Physical Geography, and a complete Description, from the most recent sources, of the Political and Social Condition of all the Countries in the World; with numerous Statistical Tables, and an Alphabetical Index of 12,000 Names. 8vo. 30s. cloth. MARCET (MRS.)-CONVERSATIONS ON THE HISTORY OF ENGLAND. For the Use of Children. Bv Mrs. Marcet, author of " Conversations on Chemistry," etc. 2d Edition, ISmo. os. cloth. Part II. continuing the History to the Reign of George the Third, separately. Is. M. •' Juvenile literature will freely own hoii> much it ij indebted to Mrs. Marcet, not only for thf present, but all her preceding works. She imparts interest to dry and dull details; and, irhile she teaches, begets a desire in her pupils for further knoirledge, so pleasantly imparted. 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Of the General Properties of Bodies; the At- traction of Gravity; the Laws of Motion; Compound Motion; the Mechanical Powers ; Astronomy; Causes of the Earth's Motion i the Planets; the Earth ; the Moon; Hydro- statics; the Mechanical Properties of Fluids ; i Opt MARCET.— CONVERSATIONS ON POLITICAL ECONOMY; In which the Elements of that Science are familiarly explained. 7th Edition, revised aud enlarged, 1 vol. foolscap 8vo. 7s, 6d. cloth. CONTENTS. of Springs, Fountains, etc.; Pneumatics; the Mechanical Properties of Air; on Wind and Sound; Optics; the Visual Angle and the Reflection of Mirrors: on Refraction and Colours ; on the Structure of the Eye, and Introduction; on Property; the Dh Labour; on Capital; on Wages and Popula- tion ; on the Condition of the Poor ; on Value and Price; on Income; Income from Landed Property; Income from the Cultivation of nd ; Income from Capital lent; on Money; Commerce ; on Foreign Trade; on Ex- nditure and Consumption. 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MAUNDER.— THE TREASURY OF HISTORY; Comprising a General Introductory Outline of Universal History, Ancient and Modern, and a Series of separate Histories of every principal Nation that exists ; developing their Rise, Progress, and Present Condition, the Moral and Social Character of their respective Inhabitants, their Religion, Manners, and Customs, etc. etc. By Samuel Maunder. Fcap. Svo. 10s. clothj bound in roan, 12s. ** In the * Treasuri/ of History' we see the same utility of purpose, the same diligence and painstahine; with the materials, the same skill and talent in putting them together, and, in fine, the same t^eneral ea-celleuce which have marked all Mr. Mnunder's productions. The arrangement is most clear and judicious, and the infor/nntion furnished at once so concise and ample, that within this small volume we Jind a very complete and satisfactory epitome of the history of the world from ancient to modern times.^' — Literary Gazette. MAUNDER.— THE TREASURY OF KNOWLEDGE, And LIBRARY of REFERENCE: containing a new and enlarged Dictionary of the English Language, preceded by aCompendious Grammar, Verbal Distinctions, etc. ; a new Universal Gazetteer; a Compendious Classical Dictionary; a Chronological Analysis of General History; a Dictionary of Law Terms, etc. etc. By Samuel Maunder. 14th Edition,;foolscap Svo., with two engraved Frontispieces, 8s. firf. cloth , bound in roan, 10s. 6rf, MAUNDER.— THE SCIENTIFIC AND LITERARY TREASURY: A New and Popular Encycloptcdia of Science and the Belles Lettres; including all Branches of Science, and every Subject connected with Literature and Art. The whole written in a familiar style, adapted to the comprehension of all persons desirous of acquiringinfotmation on the subjects comprised in the work, and also adapted for a Manual of convenient Refer- ence to the more instructed. By Samuel Maunder. 3d Edition, fcap. Svo. with an engraved Frontispiece, 10s.; bound in roan, 12s. MAUNDER.- THE BIOGRAPHICAL TREASURY: Consisting of Memoirs, Sketches, and brief Notices of above 12,000 Eminent Persons of all Ages and Nations, from the Earliest Period of History; forming a new and complete Dic- tionary of Universal Biography. 4th Edition, with a " Supplement,'^ from the Accession of Queen Victoria to the Present time. Foolscap Svo. with engraved Frontispiece, Ss. 6rf. cloth ; bound in roan, 10s. 6d. MAUNDER.—THE UNIVERSAL CLASS-BOOK: A new Series of Reading Lessons (original and selected) for Every Day in the Year; each Lesson recording some important Event in General History, Biography, etc., which happened on the day of the month under which it is placed, or detailing, in familiar language, interest- ing facts in Science ; also a variety of Descriptive and Narrative Pieces, interspersed with Poetical Gleanings : Questions for Examination being appended to each day's Lesson, and the whole carefully adapted to Practical Tuition. By Samuel Maunder, author of "The Treasury of Knowledge." 2d Edition, revised, 12mo. 5j. bound. MODERN SYRIANS; Or, Native Society in Damascus, Aleppo, and the Mountains of the Druses. FVom Notes made during a Residence in those parts in 1841, 42, and 43. By an Oriental Student. Post Svo. 10s. 6rf. *' A pleasant and sensible volume, written by an active and observant traveller, A series of short agreeable sketches of native manners, costumes, and conversations, collected during a tour in Syria, especially in the neighbourhood of Damascus, Aleppo, and the mountains of the UrMsps."— Athena!um. MONTGOMERY'S (JAMES) POETICAL WORKS. New and only complete Edition. With some additional Poems and Autobiographical Prefaces. Collected and edited by Mr. Montgomery. 4 vols, foolscap Svo. with Portrait, and 7 other beautifully sngraved Plates, 20s. cloth ; or bound in morocco, with gilt edges, 1/. 16s PRINTED FOR LONGMAN, BROWN, AND CO. 23 MOORE'S POETICAL WORKS; Containing thu Author's recent Introduction and Notes. Complete in one volume, uniform with Lord Byron's Poems. With a New Portrait, by George Richmond, engraved in the line manner, and a View of Sloperton Cottas;e, the Residence of the Poet, by Thomas Creswick, A R.A. MediumSvo 1/. l5. rloth. *.* Also, an Edition in 10 vols, foolscap 8to. with Portrait, and 19 Plates, 21. lOJ. cloth; morocco, 4/. 10s. MOORE'S LALLA ROOKH. Twentieth Kdition (1842), 1 vol. medium 8vo. beautifully illustrated with 13 Engravings, finished in the highest style of art, -]s. handsomely bound in cloth and ornamented; morocco, 35j. ; or 4i3. with 1 ndia Proof Plates, cloth. MOORE'S LALLA ROOKH. 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" Mr. Moore fortunately brings to his labours not only extensive learning in the rarely- trodden paths of Irish bistort/, bat strict impartiality, rendered still more clear and uncom- promising by an ennobling love of liberty. Every page of Ids work contains evidence of research; and innuinerable passages might be cited in proof of the independent and truth- seeking spirit of the author.''— Atheuxuni. MORAL OF FLOWERS. 3d Edition, 1 vol. royal Svo. with 24 beautifully coloured Engravings, 1/. 10s. half-bound. MORTON.— A VETERINARY TOXICOLOCICAL CHART, Containinir those Agents known to cause Death in the Horse ; with the Symptoms, Antidotes, Action on the Tissues, and Tests. By VV. J. T. Morton. 12mo. 6s. in case j 8s. 6d. on rollers. MORTON.— A MANUAL OF PHARMACY, For the Student in Veterinary Medicine ; containing the Substances employed at the Royal Veterinary College, with an Attempt at their Classification, and the Pharmacopoeia of that Institution. By W. J. T. Morton. 3d Edition, 12mo. 10s. cloth. MOSELEY.— ILLUSTRATIONS OF PRACTICAL MECHANICS. By the Rev. H. Moselev, M.A., Professor of Natural I'hilosophy and Astronomy in King's College, London ; being the First Volume of the Illustrations of Science by the Professors of King's College. 1 vol. feap. Svo. with numerous Woodcuts, 8s. cloth. MOSELEY.— THE MECHANICAL PRINCIPLES OF ENGINEERING AND ARCHITECTURE. By the Rev. H. Moselev, M.A.F.R.S., Professor of Natural Philosophy and Astronomy in King's College, London; .and author of "Illustrations ot Mechanics," cti-. 1 vol. Svo. with Woodcuts and Diagrams, H.48. cloth. •' The worh of Mr. Moseley is an elaborate, profound, accurate, and eteirant abstract, and purely mathematical disijnifition, on the theoretical principles of mechanics ; and mill serve to increase the author's high reputation as a mathematician." — t^\.\\c\\^\\xA, MULLER.— INTRODUCTION TO A SCIENTIFIC SYSTEM OF MYTHOLOGY. By C. O. 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MURRAY.-ENCYCLOP/EDIA OF GEOGRAPHY; Comprising a complete Description of the Earth: exhibiting its Relation to the Heavenly Bodies, its Physical Structure, the Natural History of each Country, and the Industry, Com- merce, Political Institutions, and Civil and Social State of all Nations By Hugh Murray, F.R.S.F,.: assisted in Astronomy, etc. by Professor Wallace; Geology, etc. by Professor Jameson; Botany, etc. by Sir W. J. Hooker; Zoology, etc. by W. Swaiiison, Esq. New Edition, with Supplement, bringing down the Statisticaf Information contained in the Work, to December 1813: with >fi Maps, drawn by Sidney Hall, and upwards of 1000 other Engravings on Wood, from I)ra\yings by Swainson, T. Landseer, Sowerby, Strutt, etc. repre- senting the most remarkable Olijccls of Nature and Art in eyery Region of the Globe. 1 vol. 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Reid, M.D. F.R.S.E. etc. Svo. with Diagrams, and a'U Eneravini^s on Wood, ICs. cloth. b , g a ingson " /Ke regard this as a booh of considerable interest and importance, and which mu>l com- mand a large share of public attention, as it contains a complete development of the tlieoru and practice— that is, the science and the art of ventilation, made known to the public lor the first time. There is not a chapter that does not offer a great number of novel and important suggestions, well worthy of the careful consideration alike of the public and the professions. It is, besides, full of curious illustrations; the descriptions and application of the 'principles' being interspersed throughout, with a variety of umusin" anecdotes bearinir upon the general suiject."-MurmngChiumclt:. »""i KEPTON.— THE LANDSCAPE GARDENING & LANDSCAPE ARCHITECTURE of the late Humphrey Hepton, Esq.; being his entire Worlis on these subjects. 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THOMSON. -AN ELEMENTARY TREATISE ON ALGEBRA, Theoretical and Practical. By James Thomson, LL.D. Professor of Mathematics in the University of Glasgow. 12mo. 5s. cloth. *' For clearness, simplicity, and completeness, it would be difficult to imagine a superior performance to Dr. Thomson's. Any intelligent indiridual might teach himself from it, and in the hands of an able master it must prove invaluable. We recommend it to mathematical readers, teachers, aud students, as incomparably the best elementary treatise and the most comprehensive text book af the science."— Atl^s. THOMSON.— THE DOMESTIC MANAGEMENT OF THE SICK ROOM, Necessary, in Aid of Medical Treatment, for the Cure of Diseases. By Anthony Todd Thomson, M.D. F.L.S. etc. 1 vol. post Svo. pp. 518, lUj. 6d. cloth. 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And a New System of Shoeing, by Onesided Nailing; and on the Nature, Origin, and Symptoms of the Navicular Joint Lameness, with Preventive and Curative Treatment. By James Turner, M.R.V.C. Royal Svo. pp. lis, 7s. 6rf. boards. TURTON'S (DR.) MANUAL OF THE LAND AND FRESHWATER SHELLS OF THE BRITISH ISLANDS. A urw E.liti.in, thcimi-hh r, vised, aiul with considerable Additions. Bv Join, K.hvaril Grriv, Kicpcr ..f th.- Zn,,l,,L;i. al C.iU.. i tii.ii in the British Museum. 1 vol. post Svo. Willi Woodcuts.and 12 coloured Plates, lis. i loth. URE.-DICTIONARY OF ARTS, MANUFACTURES, AND MINES: Containing a clear Exposition of their Principles and Practice. By Andrew Urc, M.D. F.R.S. M.G.S.M.A.S. Lond.; M. Acad.N.S. Philad. ; S. Ph.Soc.N. Germ. Hanov. ; MuUii. etc. etc. Third Edition, corrected. Svo. illustrated with I24U Woodcuts, 5U$. cloth. In the prf.ts, by the same Author, RECENT IMPROVEMENTS IN ARTS, MANUFACTURES, AND MINES; being a Supplement to his Dictionary. WALKER, (GEO.)-CHESS STUDIES : Comprising One Thousand Games actually Played during the last Half Century , presenting a unique Collection of Classical and Brilliant Specimens of Chess Skill in every stage of the Game, and thus forming a complete F^neyclopiudia of Reference. By George Walker. Medium Svo. 10s. 6d. sewed. " 7'Ats collection of specimens of chess skill is unique, and forms a complete encyelopeedin of reference to the student and phiyer. It contains npteards of KKIO games, alt'af the,,, the classical ejploits of the best chess warriors oj the itne. Knerv student and Inner of the faicinattng g-ame should possess himself of .Mr. liuU.er's 6f(«A'."— F:.\ap-.iner. WARDL.^W. -DISCOURSES ON THE PRINCIPAL POINTS OF THE SOCINIAN CONTROVERSY-theUnityofGod,and the Trinity of Persons in the Godhead -the Supreme Divinity of Jesus Christ— the Doctrine of the Atonement -the Christian Character, etc. By Ralph Wardlaw, D.D. 5th Edition, Svo. I5». cloth. WATERTON'.— ESSAYS ON NATURAL HISTORY, Chiefly Ornithology. By Charles Waterton, Esq., author of "Wanderings in South America." With an Autobiography of the Author, and u View of Walton Hall. 5th Edition, foolscap Svo. 8s. cloth. SECOND SERIES. With Continuation of Mr. Waterton's Autobiography. Fcap. Svo. with Vigi.ette by T. Creswick, A.R.A. 6s. Grf. cloth. " /( ginet us hearty pleasure to meet with .Mr. IVaterton asain. To miserable mortals ' close in populous cities pent.' his hooks ore as a vinurous autumn air. He is a charmirg uriter. Candid, rordiul. uood-hearteri, and full of the molt masculine si/mpathies. His .\iilol,i(,.;rnphv Kill rank u-ith the most piquant and compreh-nsiiie pieces of tuat hind of uritiui; in the lanLfuane. Ilis Essays, Kith little of the learned pretences, have a store of cheerful WLydom in them which i/ields unfailing instructiuensss and plea\ure.^^ l^.xantiiicr. WATIIEN.-ARTS, ANTIQUITIES/ AND CHRONOLOGY OF ANCIENT EGYPT, from Personal Oli»,rvatiojis in IKW. I'.v G. IJ. W.alic ii, Ar.:hitcct. KoyulSvo. with Plates and Woodcuts, fron. the Author's own Sketches, ll',«. i loth. " To commend or recommend .Mr. Ifatheo's volume, aflrr what we have extracted from it, would he superjluous. The aulir/uary, the scholar, the philosopher, the artist, in short, even/ educated man who reads, either for instruction or entertainment, must he interested in its rich and varied contents."— Eclcclic Review. 32 CATALOGUE OF NEW WORKS, ETC. WEBSTER.— AN ENCYCLOP>EDIA OF DOMESTIC ECONOiVlY ; Comprising such subjects as are most immediately connected with Hotisekeepiug ; Tlie Construction of Domestic Edifices, with the modes nf Warminif. Ventilatinsr, a Lightinif them— A description of the various articles of Furniture, with the natnre of thi Materials -Duties of Servants— A genernl account of the Animal and Vegetable Suhstanc used as Food, and the methods of preserving and preparing them by Cooking— Mak Bread— The Chemical Nature and the Preparation of all kinds of Fermented Liquors ul as Beverage — Materials emploved in Dress and the Toilet — Business of the Launir; Decription of the various Wheel Carriages— Preservation of Health-Domestic Medici etc. etc. etc. By Thomas Webster, F.G.S., etc.; assisted bv The late Mrs. Parkes, autl of " Domestic Duties." 1 thick vol. .8vo. illustrated with nearly lUOU Woodcuts. oOj. i "TAe title-page sufficientlu itidicatei the aide range nf topics inrlnded in this mmt usej Encyclopedia, and all are treated with a fulness which leaves nothinir to br desired. It h been the object of the editor to combine science with practice, a knowledge of principles w the ordinari) details and daily recurring duties of domestic life. In some departments of t tcork Mr. Webster has been assisted bv a ladi/ whose quaVifications are bei/nnd dispute, . the result of their united labours is the production of a volume which exhausts the subi and defies all competition. The work is richly illustrated with woodcuts, adding greath its rialue. We strongly recommend every ladu, and all others who are concerned in management of domestic a fairs, to make themselves familiar with Mr. Webster's volume, wl muit speedily be regarded as an indispensable book of reference to every housekeep^ Ecle : Re WESTWOOD.— INTRODUCTION TO THE MODERN CLASSIFICATION C INSECTS ; comprising an Account of the Habits and Tr.ansformations of the differe Families ; a Svnopsis of all the British, and a Notice of the more remarkable Fore Genera. By J.O. Westwood, Sec. Ent. Soc. London, F.L.S.. etc. 2 vols, illustrated n above 150 \Voodcuts, comprising about 2500 distinct Figures, 2/. "is. cloth. WHITE'S COMPENDIUM OF THE VETERINARY ART ; Containing Plain and Concise Observations on the Construction and Management of t Stable; a brief and popular Outline of the Structure and Economy of the Horse ; theNatat Symptoms.and Treatment of the Diseases and Accidents to which the Horse is liable : theb Method of performing various Important Operations ; with Advice to the Purchasers of Horse and a copious Materia Mcdica and Pharmacopoeia. 17th edition, entirely reconstructed, wi considerable Additions and .\lterations, bringing the work up to the present state of Vete uary Science. By W. C. Spooner, Svo. with coloured Plate, 16>. cloth. WHITE'S COMPENDIUM OF CATTLE MEDICINE ; Or, Practical Observations on the Disorders of Cattle ,ind other Domestic Animals, exce the Horse. 6th Edition, re-arranged, with copious Additions and Notes. By W. C. Spoon< Vet. Surgeon, author of a "Treatise on the Influenza," and a "Treatise on the Foot a Leg of the Horse," etc. Svo. 9s. cloth. WHITLEY.— THE APPLICATION OF CEOLOCY TO AGRICULTURE; And to the Improvement and Valuation of Land : with the Nature and Properties of Soi and the Principles of Cultivation. By Nicholas Whitley, Land Surveyor. Svo. 7s. 6d. WILDE. -NARRATIVE OF A VOYACE TO MADEIRA. TENERIFFE, AN ALONG THE SHORES OF THE MEDITERRANEAN. By R. Wilde, Surgeon, 2d Edition, corrected and enlargeO, Svo. with Illustrations, I8s. cloth. WILKINSON.— THE ENGINES OF WAR, ETC. Being a History of .\ncient and .Modern Projectile Instruments and Engines of Wai Sporting; including the Manufacture of Fire Arms, the Histon- and Manufacture of Gu powder, of Swords, and of the cause of the Damascus Figure in Sword Blades, with soi Observations on Bronze: to which are added. Remarks on some Peculiarities of Iron, and the extraordinary Effect produced bv the Action of Sea Water on Cast Iron ; with Detail various miscellaneous Experiments; By H.Wilkinson, M.R.A.S. Svo. 9s. cloth. WILLOUGHBY (L.-^DYj-A DIARY. Purportiug to have been kept bv LADY WILLOUGHBY of Parham, in the Reign Charles I.; embracing some Passages of her Domestic History from lli35 to 164S. To give additional interest to the work, it has been printed and bound in the style of period to which it refers. Small 4to. ISs. boards ; or in morocco, by Hayday, 21. is. " The real Lady Willoucrhby could not have left a more beautiful, a more affecting, t more instructive record. The pleasures and pains of the domestic life of a young mart woman in the first fourteen years of her marriage ; that blending of welcom responsibilities with trembling and tearful enjoyments maidenhood to wifehood and • • ■ delicacy." — Examiner. WOOD.— A PRACTICAL TREATISE ON RAILROADS, AND INTERIC COMMUNICATION in GENERAL. Coiitainini; numerous Experiments on the Powers the Improved Locomotive Engines, and Tables of the comparative Cost of Conveyance Canals, Railways, and Turnpike Roads. By Nicholas Wood, Colliery Viewer, Memb. In Civ. Eng. etc. ' Third edition, very greatly enlarged, with 13 large Plates, and several n^ Woodcuts. 1/. lis. 6rf. cloth. YOUNG LADIES' BOOK (THE): transition fr' rhood; tuere never drawn with a hand of more estjuisi .\ Manual of Elegant Recreations, Exercises, and Pursuits. 4th Edition, with numero beautifully execuled Engravings on Wood. i;. Is. elegantly bound in crimson silk, lin with imitation of Mechlin lace. 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