~~~~~~~4 ~~~~~~~~~~~~~~~~~~........ 7........ FORBES UTMCO.SOST~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~t4....... The frndus of th e e as seen with the ophthalmoscope. After Von Jaege......,.f.rs. published in 185G. The face of the optic disc should be wore pinkish in..........color The arteries of the retina are the lighter, the veins the darker vessels........... A TREATISE ON DISEASES OF THE EYE; FOR THE USE OF btutentO antb 0eneral practitioner. TO WHICH IS ADDED A SERIES OF TEST TYPES FOR DETERMINING THE EXACT STATE OF VISION. BY HENRY C. ANGELL, M.D., PROFESSOR OF OPHTHALMOLOGY IN THE BOSTON UNIVERSITY SCHOOL OF MEDICINE. SEVENTH EDITION, REWRITTEN AND ILLUSTRATED. BOSTON: OTIS CLAPP AND SON. 1891. Copyright, 1891, BY HENRY C. ANGELL. nANbersitgt ress: JOHN WILSON AKD SON, CAMBRIDGE. PREFACE TO THE SEVENTH EDITION. THE present edition is mostly re-written, and is more fully illustrated than its predecessors. It is also favored with contributions from my friend Dr. F. Park Lewis, of Buffalo. His articles are placed in brackets and marked by his initials. As in former issues, the aim has been to make the book suitable for the use of physicians in general practice. BOSTON, April, 1891. PREFACE TO THE SIXTH EDITION. THE sixth edition is remodelled and to a certain extent rewritten. As heretofore it has not been thought advisable to devote great space to the indication for the use of internal remedies. Such indications can be found elsewhere, and their consideration might easily be made to double or treble the size of the book. The main purpose of the work is to make the nature and diagnosis of -ophthalmic affections comprehensible to the non-specialist, and after this, to teach how to avoid the bad, and how to avail of the good, in the topical, mechanical, and surgical treatment of the various defects and diseases of the eye. BOSTON, January, 1882. PREFACE TO THE THIRD EDITION. AN attempt has been made in this edition to bring the work up to date in ophthalmologic science, without materially increasing its size. Alterations or additions have been made in nearly every chapter, and a Glossary of scientific terms has been placed before the Table of Contents, which may be of convenience to students and others. BOSTON, August, 1873. PREFACE TO THE FIRST EDITION. MY readers are requested to bear in mind that this work is written, not for specialists, but for homceopathic physicians in general practice, - for those too busied with the whole to devote a great amount of time to any one part of medicine and surgery. The endeavor has been to treat the subjects embraced clearly and concisely, in the hope of presenting a volume attractive enough, and small enough, to induce the busiest to give it some attention. In the preparation of this work, I have had the advantage of copious notes taken during a somewhat prolonged attendance at the European clinics; and I have availed myself without hesitation, also, of the privilege of taking and appropriating whatever I have found desirable in the standard or periodical works devoted to ophthalmology. BOSTON. March, 1870. CONTENTS. CHAPTER T. PAGE BRIEF SKETCH OF THE RISE AND PROGRESS OF OPHTHALMIC SURGERY................. CHAPTER II. ANATOMY AND PHYSIOLOGY. The Eye, as a whole, best described by the use of Geographical Terms.- The different Tissues of the Globe.- Ciliary Muscle. - Optic Nerve. — Tenonian Capsule and Lymph Spaces. - Tears and Secretion of Conjunctiva. - Physiology of Vision. - Excitation of Nerves. - Act of Seeing. - Eye as an Optical Instrument. - Irremediable Optical Defects...... 5 CHAPTER III. EXAMINATION OF THE EYES. Objective and Subjective Examination.- Implements and Instruments. - Bandaging the Eye.......... 26 CHAPTER IV. THE OPHTHALMOSCOPE. The Principle of.- How to use it. - What to observe.- Lateral Illuminationo - Difficulties of Diagnosis formerly. - Importance of the Ophthalmoscope to the General Practitioner... 37 X..CONTENTS. CHAPTER V. REFRACTION, ACCOMMODATION, AND THEIR ANOMALIES. PAGE Myopia. - Hypermetropia. - Accommodative Asthenopia. - Astigmatism. - Cylindrical Glasses. - Muscular Asthenopia. Presbyopia. - Prisms for testing the Equilibrium of the External Muscles... 49 CHAPTER VI. THE CONJUNCTIVA, Passive Hyperemia of the Conjunctiva.- Simple, Catarrhal, Purulent, Egyptian, Congenital or Infantile, Prophylaxis in Infantile, Gonorrhceal, Diphtheritic, Follicular, and Granular Conjunctivitis. - Pannus. - Scrofulous Ophthalmia. - Phlyctenular and Exanthematous Conjunctivitis. - Pterygium. - Pinguecula. - Warts, Cysts, and Dermoid Tumors ai;d Hemorrhage of the Conjunctiva........... 94 CHAPTER VII. THE CORNEA AND SCLERA. Phlyctenular and other Forms of Keratitis: Ulcerations of the Cornea. - Staphyloma Anterior.- Conical Cornea. - Arcus Senilis.- Opacities of the Cornea. -Episcleritis.- Staphyloma of the Sclerotic.............. 134 CHAPTER VIII. THE IRIS. Hyperaemia of the Iris. - Simple, Rheumatic, Suppurative, and Serous Iritis. -- Prolapse of the Iris. - Cyclitis. - Artificial Pupil. - Mydriasis. - Myosis. - Action of Atropine. - Action of Eserine, Pilocarpine, Duboisine, Gelsemine, Homatropine, and Cocaine. - Iridodonesis. - Cysts of the Iris... 155 xii CONTENTS. CHAPTER XIII. THE CRYSTALLINE LENS. PAGE Cataract. - Complications with other Affections. - The Cause of Cataract. - Hard and Soft Cataracts. - Nuclear, Striated, Black, and Siliquose Cataract. - The Infantile, Lamellar, and Cortical Varieties. - The Various Operations by Extraction, Absorption, and Depression. - Secondary Cataract. - Capsular Cataract. -Dislocation of the Lens. - Traumatic Cataract.- Aphakia............ 235 CHAPTER XIV. SPECTACLES - ARTIFICIAL EYES. Cataract Glasses. - Pantoscopic, Prismatic, and Stenopaic Spectacles.- Eye Protectors.- Artificial Eyes. - The Dioptric System of Enumeration of Lenses........ 257 CHAPTER XV. THE MUSCLES OF THE EYE. Paralysis of all the different Muscles of the Eyeball, and of the Ciliary Muscle. - Spasm of Ciliary Muscle. - Strabismus, Convergent and Divergent. - Operations for the Division of the Muscles.... 263 CHAPTER XVI. THE EYELIDS. Blepharitis. -Acne Ciliaris. - Herpes Zoster Frontalis.- Ectropium.- Entropium. - Meibomian Cyst. - Other Tumors — Hordeolum. - Epicanthus. - Lagophthalmos. - Blepharospasm. - Ptosis........... 280 CONTENTS. xi CHAPTER IX. THE CHOROID AND VITREOUS. PAGE Hyperaemia of Choroid. - Simple, Disseminated, Syphilitic, and Suppurative Choroiditis. - Hyalitis, Simple and Suppurative. - Opacities of the Vitreous. - Muscee Volitantes. - Hemorrhage into the Vitreous.- Synchysis. - Sparkling Synchysis. — Cysticerci of the Eye............ 172 CHAPTER X. GLAUCOMA. Acute, Subacute, Chronic Inflammatory, Chronic Non-inflammatory, and Absolute Glaucoma. - Glaucoma Fulminans. - Iridectomy. - Sclerotomy. - Other Operations for Glaucoma. 181 CHAPTER XI. THE RETINA AND OPTIC NERVE. Retinal Hyperemia. - Retinitis Serosa, Exudativa, Albuminurica Syphilitica, Apoplectica, and Pigmentosa.- Detachment of Retina.- Glioma Retine. - Ischlemia Retine. - Paralysis of Retina. -Embolism of the Central Artery of the Retina. Neuro-Retinitis. - Atrophy of Nerve....... 199 CHAPTER XII. AMBLYOPIC AND OTHER AFFECTIONS. Diagnosis of and Various Causes of Amblyopia.- Simulation of Blindness. - Hemeralopia. - Color Blindness.- Retinal Asthenopia.- Anaesthesia Retinae- Neuralgia Oculi.- Effects of Electric Light................. 222 CONTENTS. xiii CHAPTER XVII. THE LACHRYMAL APPARATUS. PAGE Epiphora and Stillicidium Lachrymarum. - Inflammation of Sac. Blenorrhcea of Passage. - Stricture. - Dilatation of Sac. Fistula. - The Probe, the Style. Stilling's Operation. The Lachrymal Gland.. 289 CHAPTER XVIII. AFFECTIONS OF THE WHOLE EYE AND OF THE ORBIT. Hydrophthalmia. - Medullary Cancer. - Grave's Disease. - Affections of the Orbit............ 302 CHAPTER XIX. INJURIES OF THE EYE. The Lids. - The Conjunctiva. - Anchyloblepharon. Symblepharon. - Foreign Bodies within the Globe. - Use of the Magnet. -- Injuries of the Cornea, the Iris, the Lens, the Sclerotic. - Hemorrhage into the Anterior Chamber. - Sympathetic Ophthalmia. - Sympathetic Irritation.- Removal of the Eye. - Division of the Optic and Ciliary Nerves. - Exenteration................ 305 CHAPTER XX. THE EYE IN RELATION TO THE GENERAL SYSTEM. In Diagnosis. - In regard to its own Integrity. - As a Possible Cause of Functional Nervous Disease....... 322 xiv CONTENTS. CHA.PTER XXI. PAGE LIST OF A FEW INTERNAL REMEDIES, WITH THE OPHTHALMIC AFFECTIONS, OR TIIE SUBJECTIVE AND OBJECTIVE SYMPTOMS OF THE EYES, FOR WHICH THEY HAVE BEEN FOUND USEFUL IN THE PRACTICE OF THE WRITER. External Remedies.......... 330 CHAPTER XXII. TEST TYPES. First Series. - Second Series. - Tests for Astigmatism... 338 INDEX......... 349 GLOSSARY. REFRACTION.... The power of the eye to focus rays of light. ACCOMMODATION... Power of the eye to adjust the vision for different distances. ASTIGMATISM..... Irregular refraction, an optical defect. HYPERMETROPIA.... Over-sight. Deficient refraction. MYOPIA...... Near-sight. Excessive refraction. PRESBYOPIA... Old-sight. Deficient accommodation. OPTICAL DEFECT... Defective power of accommodation or refraction.1 Error of refraction. AMETROPIA..... The general term for an optical defect of any kind, impairing vision. ANISOMETROPIA... Unequal refractive power of the two eyes in a person. E.IMETROPIA..... Without error of refraction. An emmetropic eye is supposed to be optically perfect. AMBLYOPIA..... Impaired sight, not due to refractive errors alone. Obscure diseases of the fundus. OPTIC DIsc...... Optic nerve at its entrance of the eye as seen with the ophthalmoscope. STAPHLYOMA POSTICUM. Bulging of the coats of the eye posteriorly around the optic disc. FUNDUS...... Back part of the interior of the eye. TENSION....... Hardness or softness of the eyeball. 1)IPLOPIA..... Double vision. PHOTOPHOBIA... Intolerance of light. ASTHENOPIA... Weakness of sight. THE MEDIA..... The transparent cornea, lens, aqueous and vitreous humors. 1 Exceptionally, "optical defect" may mean defective sight from disease of the transparent media, namely, corneal opacity, etc. DISEASES OF THE EYE. CHAPTER I. BRIEF SKETCH OF THE RISE AND PROGRESS OF OPHTHALMIC SURGERY. IT appears that the ancient Egyptians were the first to divide the practice of medicine and surgery into distinct departments, and that in those days there were practitioners who devoted themselves especially to the study and treatment of diseases of the eye and ear. Recently published translations from a work written a thousand years before the time of Hippocrates show that eye diseases were better known at that time than had been supposed. That greater progress was not made in medicine at that epoch is to be attributed to the primitive condition of anatomy and pathology, and to the fact that whatever knowledge of this kind existed was regarded as the exclusive property of its possessor, to be left like an heirloom to his family or his successor. The Arabians, Greeks, and Romans possessed considerable information in regard to diseases of the eye; and Celsus, in the first century, wrote accurately on diseases of the eyelids, described pterygium, and an operation for its removal not unlike that practised at the present day. 1 2 OPHTHALMIC SURGERY. After this we hear little of affections of the eye, until the beginning of the eighteenth century; and even as late as this, oculists were but itinerant quacks and lecturers who trumpeted their fame at fairs, in front of the booths in which they practised. There were female oculists also in those days. An author of that time says, "About five years since, I saw a woman in Holborn, by King's Gate, that had a dissolution of vitreous humor in the right eye, a narrowness of the inward chamber and immobility of the pupil, and half was dilated. The crystalline was opaque and shrunk in its bigness, pressed against the pupil and was of whitishgray, by reason of the fibrous parts of its crooked and contracted segments, so that she could not perceive any light with that eye. She asked me if I could do her any good; I told her there was no hope, for she could not see the least glimmering because her cataract was accompanied with a gutta serena which was perfect. She told me that Mrs. Jones, a famous woman for couching of cataracts, would have couched her some years before." The same author writes of the "Cataplexia of the eye which Hippocrates speaks of," and goes on in this remarkable way: "Some call this the conick movement which is the parrexis or helcosis and abruption precision, or ulceration and solution of the continuity of the optic nerve, caused from a stroke, wound, or fall of humors or apostimation." He says further that the " Syntosis of Galen or the syntomosis is a collaption, compression, flabbiness of said nerve, which is affected by dryness," and so on. Some of the remedies in use only one hundred and fifty years ago ITS RISE AND PROGRESS. 3 are equally remarkable. A scarificator was made of beards of barley tied into a little brush. Applications in common use were vipers' fat, gall of the eel and pike, a mixture of ants and honey, and applications of a less delicate nature. As original and curious as any, was the insertion in the eye of a living louse, of which it was remarked, that "it tickleth and pricketh and rendereth the eye moist and rheumatic." Towards the middle of the last century the attention of the profession, especially in Germany, began to be directed towards the study of ophthalmology, and this awakened interest finally led, in 1773, to the foundation at Vienna, in connection with the University, of a department of ophthalmology. This school became famous for its successful and distinguished teachers, and in this respect flourished without a rival for many years. About the year 1840, Dieffenbach, of Berlin, first practised his operation for strabismus, the success of which gave an impulse to the study of the physiology and pathology of the muscles of the eyeball. We come now to the year 1851, the date of the discovery of the ophthalmoscope. From the very earliest times the luminosity of the eye, especially in the cat and the dog, had been observed, and had been regarded by the people with superstitious awe. In the year 1704, Mery saw the retinal vessels in the eye of a cat under water, but not until some years later was the cause of this luminosity properly referred to light received into the eye from without. Cumming, in 1846, came very near depriving Helmholtz of the honor of his great discovery; and Reute, who improved the ophthalmoscope 4 OPHTHALMIC SURGERY. in 1852 and rendered it practical, may be fairly said to divide the honor of its invention with Helmholtz. Since the discovery of this instrument the progress of ophthalmology in all its branches has been not only rapid beyond precedent, but more rapid than the most sanguine could have hoped for. It is impossible here to more than allude to some of these great advances and their results. Recognition and accurate description of the different diseases of the optic nerve and retina, and their frequent connection with affection of the brain, heart, and kidney; diagnosis of diseases of the choroid and vitreous; classification of opacities of the lens giving rise to variety and improvement in operations for cataract; the operation of iridectomy, rendering glaucoma a curable disease; improved methods of making artificial pupil; rational surgical treatment of disorders of the lachrymal apparatus; demonstration of the laws of refraction and accommodation of the eye, which has been of incalculable value in the diagnosis and treatment of a large class of cases due to imperfect vision; the diagnosis and relief of astigmatism; the treatment of asthenopia and insufficiency of the ocular muscles; the progress in entoptics; the detection of. cysticerci in the eye; the introduction of the use of atropine, eserine, and especially cocaine; the less indiscriminate use of caustics, - these and many other improvements in diagnosis and treatment, which I do not mention even by name, were and are the results of the marvellous impulse given to the study of disease of the eye by the discovery of the ophthalmoscope. CHAPTER II. ANATOMY AND PHYSIOLOGY. ANATOMY. IT is proposed in this chapter to give simply the essential points in the anatomy and physiology of the eye, such as it would seem almost imperative that every student and practitioner should be familiar with. GENERAL DESCRIPTION OF THE EYEBALL. The spherical organ of vision, or globe of the eye, resting upon a cushion of fat within the orbital cavity, movable in all directions, directly communicating with the brain through the optic nerve, is best described, as a whole, by the use of geographical terms. The eyeball is the globe; the anterior pole, the centre of the cornea; the posterior pole, the centre of the fundus; and an imaginary line, passing through the centre of the globe, connecting the poles, is the axis. An imaginary plane, perpendicular to the axis dividing the globe into a posterior and anterior hemisphere, is the equator. The vertical meridian divides the globe into a nasal and temporal hemisphere, and the horizontal meridian divides it into a superior and inferior hemisphere. The main envelopes or coats of the globe are three: the sclerotic and cornea, the choroid, and the retina. 6 ANATOMY AND PHYSIOLOGY OF THE EYE. THE SCLEROTIC, OR SCLERA, is the outer and protective coat, and, if we include the cornea, may be said to completely cover the eyeball. It is fibrous in structure, a firm, dense membrane, provided with lymph channels, bluish-white in youth, as seen through the conjunctiva, and yellowish-white in adult or old age. Posteriorly, the sclerotic is partly merged in the sheath of the optic nerve at its entrance into the eye, but a fine tissue from it and the choroid, interwoven with the neurilemma of the optic nerve, passes across the nerve entrance, being perforated like a sieve for the passage of the optic nerve fibres. This opening in the sclera is two millimetres (a millimetre being one twenty-fifth of an inch, or about half a line) in diameter, and the sieve-like membrane covering it is known as the lamina cribrosa. The sclera is rather more than a millimetre in thickness posteriorly, but becomes gradually thinner as it approaches the front of the eye, until it receives the tendons of the four straight muscles near the edge of the cornea. Anteriorly, the fibres of the sclera are merged in the cornea; and, near the periphery of the latter, it encloses a circular canal called the canal of Schlemm, which gives passage to a plexus of veins. Posterior to this canal, in the trabecular tissue near the junction of the iris and the membrane of Descemet are the lymph spaces of Fontana. The sclera is not rich in blood-vessels, and probably has no supply of nerves at all; but, near the optic nerve entrance, and anteriorly, near the cornea, it is pierced by so THE CORNEA. 7 many nerves and vessels for the supply of other parts of the eye, that its firmness in these places is considerably lessened. THE CORNEA, which forms the transparent front of the globe, is curved so as to form a segment of a smaller sphere than the sclerotic. It is also a firm, dense membrane, and of about the same thickness as the sclera, but thinner ~~~ c~~~~ —--— ~~~~~~~~~~~ of about the same thickness as the sclera, but thinner 8 ANATOMY AND PHYSIOLOGY OF THE EYE. at the centre than at the periphery. It is divided into five distinct layers. From the outside we have: — 1st. The epithelial layer. 2d. The elastic layer of Bowman or Reichart. 3d. The true cornea. 4th. The layer of Descemet. 5th. The internal epithelial layer. The corneal substance is permeated by a system of intersecting canals, through which it is nourished by the lymph vessels at its margin. The layer of Descemet does not suppurate in keratitis. See page 140. In youth, the cornea is very, though not perfectly, transparent, but in old age the marginal portion becomes more or less opaque from fatty degeneration. The circle of opacity thus formed is called arcus senilis. The cornea contains no blood-vessels except near its edge; when, therefore, they are seen upon it, disease is present. It is largely supplied with nerves. A convenient division of the cornea, for the purpose of designating different portions of its surface, is by a vertical and horizontal meridian, which gives us four quadrants: an outer and inner superior, and an outer and inner inferior. THE CHOROID, OR UVEAL TRACT. The second coat of the globe is a vascular and pigment tunic, covering the eye posteriorly, and extending forward and forming a part of the ciliary body and the iris. These tissues together form what is termed the uveal tract. Like the sclera, it is pierced posteriorly to admit the optic verve and the retinal vessels. THE RETINA. 9 Anteriorly, a short distance in front of the equator, it is merged in a circle of plaits or folds, which, taken together, form the ciliary body. The choroid is divisible into four layers: beginning at the pigment layer of the retina, they are the vitreous, the capillary, the vascular, and the suprachoroidal layers. These layers are connected by cellular tissue more or less pigmented. The pigment layer, formerly described as being the inner choroidal layer, belongs to the retina. The chief vessels of the choroid are the vena vorticosa, the trunks of which pass out through the sclera in a very oblique direction, posterior to the equator. See Fig. 3. The choroid and inner surface of the sclera are connected loosely by a delicate elastic web; and the space within the meshes of this tissue, between the two coats, is called the perichoroidal space. The nerves of the choroid are parts of the third, fifth, and sympathetic* They are the long and short ciliary nerves, and both pierce the sclera near the optic nerve entrance, passing forward over the external surface of the choroid, forming at the ciliary region the ciliary plexus, which supplies the iris, ciliary muscle, cornea, and the ciliary blood-vessels. The blood supply is from the long and short ciliary arteries. THE RETINA, forming the third tissue of the globe, may be regarded as an organized expansion of the optic nerve. It is divided by recent authorities into ten layers; namely, the internal limiting layer, the layer of nerve fibres, the ganglionic, molecular, granular, inter-granular, exter 10 ANATOMY AND PHYSIOLOGY OF THE EYE. nal granular, external limiting, layer of rods and cones, and the pigment layer. The three layers which I have italicized- the second, ninth, and tenth — are the layers of practical importance. The layer of nerve fibres is an expansion of the fibres of the optic nerve over the retinal surface. The radiation of fibres from the optic disk is not symmetrical, but, like the vessels, FIG. 4. chiefly upward and downward in direction and tending mostly towards the temporal portion, as shown in Fig. 4, after De Wecker and Von Jaeger. This layer is thicker around the nerve entrance, and gradually thins out as we approach the ora serrata. It is the conducting layer, and the ninth -the layer of rods and cones - is the percipient layer. The cones are directed towards the centre of the eye, the apex of each pointing backward, and resting on the tenth, or pigment, layer. This pigment layer - regarded formerly as a part of the THE CILIARY MUSCLE. It choroid — does not, like the nervous structure of the retina, stop in front, at the ora serrata, but passes forward, covering the ciliary body and the posterior surface of the iris. The macula lutea, situated at the posterior pole of the globe, corresponding in size to the optic disk, has in its centre a depression called the fovea centralis. The second, seventh, and ninth layers are found well represented at this spot, but the other layers are, to a great extent, wanting. The vessels of the retina, emerging from the optic disk, like the nerve fibres, pass chiefly upward and downward, curving towards the tenlporal side of the retina, dividing in an arborescent manner, avoiding always the macula lutea. THE CILIARY MUSCLE. A short distance in front of the equator, the choroid is arranged in small plaits or folds around the lens; and these ciliary processes, some seventy or eighty in number, form part of the ciliary body. The latter is made up chiefly of the ciliary muscle, covered by the choroid and the pigment layer of the retina. The ciliary muscle, or muscle of accommodation, has two sets of fibres.: the anterior, which are circular; and the posterior, which are meridional. The radiating, or meridional, fibres have their origin near the canal of Schlemm, and are lost in the choroid and ciliary processes. The development of this muscle differs greatly in different individuals, the myope having usually more meridional, and the hypermetrope more circular, fibres. The ciliary body is one of the chief secreting tissues of the eye. 12 ANATOMY AND PHYSIOLOGY OF THE EYE. THE IRIS may be considered as a continuation of the choroid. It is the iridescent, exquisitely colored membrane, the opening in which is called the pupil, that hangs as a vertical screen in front of the lens. It is attached at its margin to the internal epithelial layer of the cornea at its junction with the sclera by the ligamentum pectinatum. The pupil is not exactly in the centre of the iris, but slightly below, and towards the nasal side. The iris is more muscular than the choroid. It has a sphincter muscle for diminishing, and probably a dilator muscle for enlarging, the size of the pupil. Posteriorly, the surface of the iiis is covered by the pigment layer of the retina. Anteriorly, it receives an epithelial covering from the inner layer of the cornea. The iris is one of the extremely sensitive parts of the eye, being richly supplied with nerves as well as with bloodvessels. THE CRYSTALLINE LENS is suspended from the ciliary processes, directly behind the iris, and in contact with the pupillary margin. Posteriorly, it rests against the vitreous body which is hollowed out to receive it. It is a transparent, bi-convex body, enclosed in a transparent capsule, about nine millimetres in diameter, and three or four in thickness. It is laminated in structure, and more convex posteriorly. The centre, or nucleus, is harder than the marginal or cortical portion. The lens becomes harder and less elastic as life advances; and, by the same stages, THE VITREOUS HUMOR. 13 changes from a colorless substance in youth to a strawcolor, and finally, in old age, to a brownish-amber tint. It also enlarges in size with advancing age, but if cataractous, becomes less in size and weight. For purposes of description, it may have, like the globe, a posterior and anterior pole, an equator, and, liketthe cornea, quadrants. The capsule is spoken of as the posterior and anterior capsule. The lens has neither vessels nor nerves. THE ZONULE OF ZINN, or suspensory ligament of the lens, is the medium by which the ciliary muscle acts upon the lens or its capsule in accommodation. It is a delicate, transparent tissue from the hyaloid, or investing membrane of the vitreous, which, in front, passes between the margin of the lens and the ciliary body, and is inserted into the anterior and posterior capsule, near the equator. The existence of circular fibres has recently been discovered in this tissue. THE VITREOUS HUMtOR (VITREOUS BODY) occupies the entire posterior part of the globe between the lens and the fundus enclosed in the delicate hyaloid membrane. It is a jelly-like body, nearly colorless, and consists of about ninety-eight parts water. It has cells but neither vessels nor nerves. The hyaloid canal, containing a watery fluid, passes from the posterior capsule of the lens to the optic disk, directly through the vitreous. 14 ANATOMY AND PHYSIOLOGY OF TIE EYE. THE AQUEOUS HUMOR occupies the portion of the eye in front of the lens and posterior to the cornea called the anterior chamber. It also fills the small space between the posterior surface of the iris towards its periphery and the lens called the posterior aqueous chamber. It is nearly pure water, and, when evacuated, rapidly re-secretes. SECRETION OF THE INTRA-OCULAR FLUIDS. The capillary layer of the uveal tract is supposed to be the active agent in the secretion of these fluids which pass outward to the suprachoroidal space and also inward through the'retina into the vitreous, thence through the lens to the Zonule of Zinn into the anterior chamber, mixing with the fluid secreted by the ciliary body and iris, and forming the aqueous humor. The exit is supposed to be chiefly through Fontana's spaces and the canal of Schlemm. From these openings it gradually passes through interfascicular lymph spaces in the sclera to the space of Tenon and thence to the vaginal spaces of the optic nerve. THE OPTIC NERVE has its origin in two roots, chiefly from the corpora geniculata, but also from the thalmus opticus and the corpora quadrigemina. At the optic commissure, or chiasma, there is a complicated intercrossing of the nerve fibres, as explained on page 220. The nerve brings with it from the brain an inner sheath, or neurilemma, the delicate fibres of which enclose a capillary THE CONJUNCTIVA. 15 network of blood-vessels from the pia mater. A second sheath, received after the nerve enters the orbit from the dura mater, divides into two layers; one lining the orbit, the other forming the external sheath of the nerve. The intervaginal space is found between the two layers of the sheaths of the optic nerve, and is continuous with the arachnoid cavity. There is also a supravaginal space between the sheath of the nerve and the neurilemma, and a perineural space between the neurilemma and the nerve itself. These spaces connect with the lymph spaces of the eye. The entrance of the nerve into the eye is about four millimetres distant from the posterior pole of the globe, towards the nasal side, and just below the horizontal meridian. The orbital portion of the nerve is rather more than one inch in length. THE CONJUNCTIVA, covering the front of the eyeball, called the ocular conjunctiva, extends back nearly to the equator, and is there reflected on to the inner surface of the eyelids. It is loosely attached to the sclera, except at the corneal margin, and is throughout very vascular. Towards the inner canthus is a fold called the plica semilunaris, a rudiment of a third eyelid; and still nearer the inner angle is the caruncle. The conjunctiva of the lids is called the palpebral, and that of the edge of the lids, the tarsal conjunctiva. The posterior portion of the conjunctival sac, where it passes from the globe to the lids, is known as the retrotarsal fold, or cul de sac, or fornix. The conjunctiva 16 ANATOMY AND PHYSIOLOGY OF THE EYE. is a mucous membrane, vascular, transparent, and, with the exception of the ocular portion, thickly studded with papillae, which increase in size as we approach the retro-tarsal fold. Here are also the glands of Krause. It is also richly furnished with blood-vessels and nerves, the latter chiefly from the tri-facial, or fifth. THE EYELIDS have for their base a thin plate of cartilage (socalled, although it is not cartilage proper, but rather a dense connective tissue), convex anteriorly, so as to fit the globe. Externally they are covered by the orbicularis muscle and integument, and internally by the conjunctiva. Beneath the external muscular covering is a connective adipose tissue, in which, near the margin of the lid, are the follicles of the cilia, or eyelashes, the sebaceous glands, and the glands of Henle. Within the cilia are also the orifices of the Meibomian glands, from which an oily matter exudes to present a barrier against the overflow of tears. The Meibomian glands are plainly visible beneath the conjunctiva; and this circumstance is often serviceable in diagnosis and treatment of disease of the conjunctiva. (See page 101.) The levator palpebrae superioris springing from the apex of the orbit is attached to the upper edge of the tarsus, and is supplied by a branch of the third nerve. THE LACHRYMAL PASSAGE. On the margin of each lid, near its inner angle, is situated the punctum lachrymalis, the delicate opening into the canaliculus leading in a horizontal direction to THE TENONIAN CAPSULE. 17 the lachrymal sac. The canaliculi, which usually meet before reaching the lachrymal sac, are about six millimetres long, and the sac which lies in the lachrymal groove, or canal, is about ten millimetres, and its continuation, the nasal duct, is of the same length. The size of these passages is further spoken of in Chapter XVII. Homers' muscle lies behind the lachrymal sac. THE LACHRYMAL GLAND is placed in the lachrymal fossa, near the outer angle of the roof of the orbit. It secretes the tears, which reach the eyeball through six to twelve minute ducts opening into the conjunctiva at its reflected portion lying underneath the gland. The tears, however, as we find them in the conjunctival sac, are made up of the secretion of the lachrymal gland plus the secretion of the conjunctiva. The latter secretes a lachrymal fluid, or tears, as well as mucus, so that the eye is still moistened, and the transparency of the cornea preserved, even if the lachrymal gland be extirpated. THE TENONIAN CAPSULE AND MUSCLES OF THE GLOBE. The Tenonian capsule is a smooth, fibrous membrane or texture, loosely embracing the globe, enveloping or ensheathing the muscles, vessels, and nerves that pass through it, having its origin in the sclera, in a circle posterior to the equator, near the entrance of the ciliary nerves, so that, posterior to this, is a free space on the sclerotica, in the centre of which is the entrance of the optic nerve. Anteriorly, this capsule loses itself 2 18 ANATOMY AND PHYSIOLOGY OF THE EYE. in the conjunctiva near the cornea. The four recti muscles of the globe — the externus, internus, superior, and inferior - have their origin at the apex of the orbit, pass forward, and are inserted by tendons about eight or nine millimetres in width into the sclera near the cornea. The line of insertion of the internal rectus is about five millimetres from the corneal margin, but the insertion of the other straight muscles is slightly further back. Where these muscles pierce the Tenonian capsule near their insertion, they receive a sheath from it which is carried forward, tnd inserted with the tendon into the sclerotic. Between the layers of the Tenonian capsule is a lymph space in connection, as proved by injections, with the perichoroidal lymph space, and, as I have stated, with the intervaginal spaces around the inner sheath of the optic nerve, and thence with the arachnoid cavity of the brain. The superior oblique has its origin with the recti muscles, runs forward through its pulley at the inner and superior angle of the orbit, and then passes under the superior rectus to its insertion in the posterior hemisphere, near the upper edge of the external rectus. The inferior oblique has its origin at the inner angle of the orbit, near the opening for the nasal duct, and, passing beneath the inferior rectus, is inserted into the posterior hemisphere, between this muscle and the rectus externus. The action of these muscles on the globe, and the nerves with which they are connected, are spoken of in Chapter XV. THE EXCITATION OF NERVES. 19 PHYSIOLOGY OF VISION. It has been already remarked that the retina is the perceptive, or, more properly speaking, the receptive, part of the visual organ, while the optic nerve completes the act of vision by carrying the retinal impression to the brain. The cornea, lens, and humors, called as a whole the refracting media, being transparent, permit the passage of the rays of light, and, having convex surfaces, bring them to a focus upon the retina. It is obvious, therefore, that either a failure of the optic nerve to convey impressions, or any disease of the retina destroying its receptive function, must occasion blindness. A loss of transparency in the refracting media, by preventing the rays of light from reaching the retina, is also fatal to vision. THE EXCITATION OF NERVES is produced through mechanical, chemical, electric, or thermometric changes. The retinal nerves are excited by rays of light, as the auditory nerves by waves of sound, the nerves of the sense of touch by contact; and, the result of this excitation being conveyed to the brain, we have the perception of sight, hearing, or touch. All nerves are apparently similar in structure; all convey impressions, when excited, at the rate of about one hundred feet per second towards either end of their fibres, the nature of the sensations conveyed depending not upon the nature of the agent employed, but entirely upon the organ with which they are connected. Motor nerves, when irritated, produce move 20 ANATOMY AND PHYSIOLOGY OF THE EYE. ment, because connected with muscles; glandular nerves, secretion, because connected with a gland; sensitive nerves, sensation, because belonging to organs of sensation. It follows, therefore, that any of the agents of excitation mentioned, if they could be brought to bear upon the nervous portion of the retina, might produce the subjective sensation of sight. Thus, pressure of the side of the eyeball with the finger, or a weak electric current through the eye, gives an impression of light to the eye, although no light is present. So disease of the eye or brain, or narcotic drugs, produce similar phenomena. The retina and optic nerve being infinitely more sensitive to rays of light than any other nervestructure of the body, and being in constant functional activity from this excitation, we naturally connect the sensation of light with the presence of light, even if no light be present. THE VISUAL PURPLE is due to a red-purple color in the outer part of the retina. It cannot be seen with the ophthalmoscope. On exposure of the eye to light, this color pales; but darkness reproduces it. It is produced by a secretion of the epithelial pigment cells of the retina; but as its increase or decrease does not correspond to the retinal current of liquid from the suprachoroid, it is not supposed to be of direct importance to vision. THE ACT OF SEEING, when we take into account its complicated nature, is accomplished in an extraordinarily short space of time. BINOCULAR VISION. 21 The luminous waves of light, moving with a velocity of 200,000 miles per second, strike the retina, are translated into molecular vibrations of nervous matter, which in turn are converted by the brain into a sensation of vision. It has been estimated that the above changes, constituting the act of seeing, require no more than the four billionth part of a second for their performance. Letters upon a printed page lighted by an electric spark have been seen in forty-eight billionths of a second. It is supposed that each rod and cone conveys its own portion of the retinal picture to the brain, so that the well-known fact that the picture as a whole, upon the retina, is reversed or inverted, offers no bar to our comprehending the fact that the brain perceives the object in its true position. This phenomenon would be inexplicable, if the retina as a whole were supposed to convey the picture. BINOCULAR VISION. It is also necessary in binocular vision that the image of the object should be caught by nearly corresponding points of the two retinae. When the two eyes aredirected towards a distant object, their visual axes are practically parallel; but, if we regard an object at a distance of eighteen inches, the two axes converge at an angle of about eight degrees. With each eye separately, therefore, we see near objects from slightly different points of view. If we regard the frustum of a solid cone, we see more of the right side of it with the right eye and more of the left side with the left eye. The mental combination of the two differ 22 ANATOMY AND PHYSIOLOGY OF THE EYE. ent perspective views gives us the idea of solidity, or a third dimension, thickness. Distance, which is the equivalent of this third dimension, is also determined by vision with both eyes. The difficulty of snuffing a candle with one eye closed is well known. We judge of distance by the muscular sense of the effort that converges the optic axes, somewhat as we judge of the weight of an object by the muscular effort required to raise it. THE EYE AS AN OPTICAL INSTRUMENT is by no means so perfect as generally supposed. Myopia, hypermetropia, and astigmatism are optical defects of a large minority of mankind, and are more or less remediable by proper treatment. These are considered elsewhere; but there are certain defects common to all eyes which may be styled IRREMEDIABLE OPTICAL DEFECTS. These are given by Helmholtz, and are chiefly as follows:a. Lack of perfect transparency in the cornea and lens, and fluorescence of both. A strong light concentrated on the cornea and lens will show each to be less clear than the aqueous between them. Fluorescence is the property that some substances have of becoming faintly luminous from blue or violet light. The bluish tint of a solution of quinine in water is an example of fluorescence. A blue light thrown into the eye shows the same haziness in the cornea and lens, and the phenomenon is supposed to be due to the presence of IRREMEDIABLE OPTICAL DEFECTS. 23 quinine or some similar substance in these structures. These parts of the eye are therefore inferior to the clear and perfectly transparent lenses used by the optician in the manufacture of optical instruments. b. Spherical aberration, due to lack of correspondence of the axes of the cornea and lens, to the lack of symmetry in the former and the peculiar structure of the latter. This constitutes a slight astigmatism, the nature of which is noticed elsewhere. c. Achromatism or chromatic dispersion of rays. The solar rays being made up of the different colors of the spectrum and each color being refracted in a different degree by the same medium, they are not united by it in a single focus. Look at a street lamp at a distance through a violet-colored glass. This stops the intermediate green and yellow rays, and allows the first and last rays, the violet or blue and the red, to pass into the eye. The result is that the red is focussed, but the violet and the blue are seen in a broad halo around the red gas-light. The reason this defect is not oftener remarked is that the intermediate rays of the spectrum being brighter, the less luminous red and blue are scarcely noticed beside the intense images of the others. Optical instruments are free from this defect. d. Slight color-blindness is common to all eyes. The eccentric portion of the retina does not perceive green and red as soon as other colors. If we test the field of vision as described on page 37, we shall find that the color of a red object is not recognizable as far away as the outline of it. The eye also fails to distinguish a difference between a white produced by the union of 24 ANATOMY AND PHYSIOLOGY OF THE EYE. scarlet and bluish-green light, and a white produced by a yellowish-green and violet; yet the first comes out black in a photograph, the latter very bright. e. The distinct part of the field of vision is very small; the entire field of vision of an optical instrument is very limited in extent, but distinct in every part. f. Muscae volitantes. These are noticed elsewhere. y. The blind spot in the retina, due to the space occupied by the entrance of the optic nerve. Make a small cross on a sheet of white paper, and three inches at the right make a black dot. Shut the left eye, and, holding the paper at arm's length, fix the right eye on the cross; on bringing the paper gradually nearer, it will be found that at about eleven inches from the eye the dot will not be seen. The blind spot is sufficiently large to hide the face of a man at six or seven feet. h. There are also gaps in the field of vision caused by the blood-vessels of the retina. These vessels running in front cast a shadow on the layer of rods and cones which lies farther back. The splits in the visual field may be recognized by looking at the sky through a delicate pin-hole in a card, moving the latter from side to side at the time. i. The yellow spot, the most sensitive point of the retina, is by virtue of its yellow tint unable to recognize weak blue light. The smaller stars are seen better by astronomers if they look slightly at one side rather than directly towards them. This formidable array of common optical defects is unnoticed by us, chiefly because, having two eyes, one makes up for the temporary visual disturbance in the IRREMEDIABLE OPTICAL DEFECTS. 25 other; even with one eye, these defects are rarely noticed, owing to the great mobility of the eye and its continuous change in direction, and to the fact that the imperfections are mostly away from the centre of the field of vision. Habit, inattention, experience, the power of accommodation, may also be given as reasons why our natural visual defects are unobserved. Nevertheless, these optical defects do exist in all eyes; and, as Professor Helmholtz observes, if an optician offered for sale an instrument with these defects, one would be justified in refusing to buy it. CHAPTER III. EXAMINATION OF TIIE EYES. OBJECTIVE EXAMINATION. AFTER a glance at the exterior aspect of the lids, their margin, the cilia, the general appearance of the eyeball as to position or prominence, we may turn our attention to the different tunics of the globe which permit of examination from without. For this purpose a good light is necessary, and the best, generally speaking, is that which falls obliquely on the eye of the patient from a very near window. A still stronger light may be had, when necessary, by lateral illumination, as explained in the chapter on the Ophthalmoscope. If we suspect a foreign body, if conjunctivitis with discharge be present, if the lids seem thickened, if any sensation is complained of beneath the upper lid, if there is enlargement of the mucous papillae of the lower lid, the upper lid should be reversed. This proceeding requires but a moment, can never do harm, and may often give us at once the key to the difficulty. To reverse the upper lid it is merely necessary to raise it slightly with the thumb of the left hand, then seizing firmly the central cilia and edge of the tarsus between the forefinger and thumb of the right hand, the lid is pulled slightly downward and away from the OBJECTIVE EXAMINATION. 27 eyeball, and while the patient is requested to look downward, at this instant the lid is tilted over the point of the left thumb, which is used as a fulcrum. If necessary, a probe may be used as a fulcrum, placing it half an inch above the margin of the lid and parallel with it. The signification of the various kinds of redness of the eye is noticed under simple conjunctivitis. The surface of the cornea should be carefully scrutinized for delicate opacity, ulceration, abrasion, or unevenness. A few weeks since a young lady called for me to aid her in the selection of suitable glasses. She did not see well at a distance. There was no refractive error; nor could I find any abnormal condition of the eye whatever. I thought of old opacity of the cornea, but did not find it. After learning, however, that in childhood she had suffered from an affection which was undoubtedly a purulent ophthalmia, I felt positive that the cornea must be at fault. On taking her again into a darkened room, and re-examining the surface of the cornea by oblique illumination, and comparing her eyes under the strong light with those of her companion, I discovered a delicate cloudiness in both corneae. Without the aid of lateral illumination and the comparison with the perfect cornea of a normal eye, the haziness might have escaped detection. The size of the pupil, its form, its mobility, and the color of the iris should be noticed. The mobility may be tested by closing the eye and then raising the upper lid gently with the thumb, observing the reduction in the size of the pupil as the light strikes the eye, or by 28 EXAMINATION OF THE EYES. shading the open eye with the hand, then removing the hand quickly. In either of these experiments the eye not under examination must be closed, to avoid sympathetic influence between the two. If the pupil is sluggish in movement, or does not appear exactly circular, if the iris is at all discolored, we should drop into the eye a solution of atropine (one or two grains to the ounce of water), in order to determine whether there is adhesion between the posterior surface of the iris and the anterior surface of the capsule of the lens. If adhesions exist, the enlarged pupil will be irregular in form. It is sometimes necessary to use a solution of atropine stronger than this, of four or six grains to the ounce, when the iris is diseased, in order to affect the size of the pupil sufficiently. See article on Mydriasis. The appearance of the surface of the iris may be abnormal as to color, texture, plastic deposits, and condylomata. The significance of these objective examinations and their details will be found when we come to speak of the diseases of the various structures of the eye. Tension or hardness of the eyeball is to be noted in order to determine the degree of intra-ocular pressure. It is determined by gentle pressure through the closed lids upon the eyeball with the tip of the forefinger. The two eyes may be compared, or a sound eye with the diseased one, in order to fix the degree of hardness or softness with more accuracy. Signs to denote the amount of intra-ocular pressure are sometimes used. Thus: T. 1, T. 2, T. 3, indicate first degree or slight, second degree or considerable, third degree or extreme tension (hardness) of the ball; while Tn., T? indicate tension SUBJECTIVE EXAMINATION. 29 normal, tension doubtful. The same letter and figures preceded by the sign minus mean reduced tension or softness of the globe. Thus: T- 1, first degree of reduced tension. The mobility of the eye is to be tested by requesting the patient to follow the finger, which is moved in various directions, in order to detect paralysis of any muscle. And the strength of the external muscles may be further tested, if desired, by prisms. See pages 85, 88. SUBJECTIVE EXAMINATION. The Pain. The nature, seat, and severity of the pain complained of by the patient are of importance as an aid to diagnosis and afortiori to the selection of appropriate remedies. A dull pain in and around the eyeball, with a sensation of heat, the pain very much increased by using the eye, points to asthenopia. Smarting and burning, or a sensation as if sand were in the eye, indicate a conjunctivitis. Severe pain with photophobia and lachrymation denotes sensitiveness of the ciliary nerves, as in deep-seated conjunctivitis, corneitis, iritis, or any inflammation affecting the ciliary region, at the junction of the cornea and sclerotica. Deep-seated pain in the eye, or just above it, recurring periodically, accompanied by dimness of vision, is to be seriously regarded, and is characteristic of beginning glaucoma. The severity of the pain, however, is not alone a safe criterion by which to judge the gravity or slightness of an affection of the eye. When present, it helps us to 30 EXAMINATION OF THE EYES. determine the nature of the disease, but it may be absent sometimes in the most serious cases, such for instance as glaucoma, amaurosis, or choroiditis. Photophobia, with no pain, or appearances of inflammation externally, indicates hyperaesthesia retine - too great a sensibility of the retina. Retinitis, by itself, is a rather rare disease, and would be characterized by a want of sensibility and the necessity of a strong light to see distinctly. The State of the Vision. The visual power of a diseased eye is an important diagnostic point in the examination. This may be determined by the use of the test types annexed to this volume. If the patient reads No. 1 or 2 readily, and also the letters of No. 12, 15, or 20, at twelve, fifteen, or twenty feet respectively, with the naked eye or by the help of suitable spectacles, his sight is perfect. His visual power = 1. Good sight for a few moments followed by confusion of vision, suggests asthenopia. Rapid diminution of vision as objects recede from the eye, points to myopia. Lack of clearness in regarding objects near and distant, indicates hypermetropia or astigmatism. Defective sight for near objects and normal vision for distance, is characteristic of presbyopia. Cloudiness of sight, improved towards night and in dull weather, suggests cataract. If "spectacles never did any good" we think of astigmatism; then amblyopia, and serious internal disease of the eye will be thought of if glasses have recently needed frequent changing, or become unserviceable. If the patient cannot see the SUBJECTIVE EXAMINATION. 31 largest sized letters, he may be able to count fingers held quite near the eye. Failing in this he may distinguish between light and darkness. Seat him before a window, and then interpose between his eyes and the light some dark object of sufficient size; or a still better test, because it admits of measurement, is to take the patient into a room from which daylight is wholly excluded. He may be able to point in the direction of the lamplight, even if it is quite dim; or he may be able to discern it only when it is very brilliant, or he may not be able to see it at all. If he cannot tell with certainty, whether we shade it from him or whether it shines full in his face, there is no vision to be improved. In these experiments, if one eye alone is being tested, the other should be covered with a folded handkerchief so as to exclude the light from it. A healthy eye will distinguish light from darkness with the lids firmly closed. The Field of Vision. The extent of the field of vision, about 900 outward, 55~ inward and downward, and 45~ upward, may be determined by directing the patient to look steadily at one finger held before his eye at a distance of eighteen or twenty inches. We then move our other hand about at a distance of two feet below, above, and on each side, from the finger towards which the patient is steadily to look, noting whether he sees the hand or can count the fingers. The finger which we hold up is at the centre of the visual field and it may be necessary to bring the other hand very near to this before it can be 32 EXAMINATION OF THE EYES. seen. A few weeks since, I found the field of vision so much narrowed in a case of retinitis pigmentosa that the patient could not distinguish an object moving until it came within an inch or an inch and a half of the centre of the field, showing that only a part even of the yellow spot itself retained its normal function. A normal eye will distinguish an object moving at a distance of from two to three feet from the central point of vision. The field of vision may be mapped out when great accuracy is desirable. Put the patient before a blackboard, at the distance of fifteen inches; make a dot for him to fix the eye on; then approach a piece of chalk in a long black handle from different directions, recording always the point where the chalk is first perceived by a dot; afterwards unite these dots by a continuous line, and the boundaries of the field of vision are sketched. There is also an instrument for accurately measuring the field of vision, called a Perimeter. Di~plopia. Double images occur in paralytic strabismus, and frequently after an operation for the cure of concomitant strabismus; it also occurs sometimes in heterophoria. See page 89. Monocular diplopia is a result of irregular refraction from abnormal curvature of the cornea or lens, of mal-position or dislocation of the lens, of inequalities of the corneal surface from old cicatrices, or of bands of membrane stretched across the area of the pupil. We may readily produce double images by holding a convex lens of medium strength partly before one eye so that we may look through it and not through it at the same time, at objects across the room. IMPLEMENTS AND INSTRUMENTS. 33 IMPLEMENTS AND INSTRUMENTS. Trial Glasses. Complete sets of trial glasses, or spectacles, are necessary for those who propose to prescribe suitable glasses for the various optical defects. The selection of proper glasses for patients is a very important and responsible duty, and should not be undertaken unless the practitioner is disposed to give sufficient attention to it to do it in a scientific manner. Let the haphazard selection of glasses be left to the itinerant vender and optician. The proper glass having been determined, its number and kind are to be written out and presented by the patient to a respectable optician. A complete outfit of trial glasses comprising the convex and concave, spherical and cylindrical, the prismatic and the colored, will amount to some two hundred, or the equivalent of a hundred pairs of spectacles. See Fig. 5. To such as do not propose a more or less complete equipment for the above purpose, I would suggest a few glasses merely as an aid in diagnosis. Weak convex lenses, of thirty, forty, and fifty inches focus, will help to determine a hypermetropia, or a beginning presbyopia. If the patient sees No. 20 at twenty feet as well with as without, or better with than without either of the glasses, he is hypermetropic. In beginning presbyopia the same glasses should aid in reading the No. 1 print. Ordinary concave glasses will aid in the differential diagnosis of a slight myopia and hypermetropia. Through concaves of thirty or forty inches focus, a myope should see distant objects more 3 34:i~SEXAMINATIO)N OF THE EYES. clearly, and a hypermetrope ess cless arl. The same spherical convex or concave glasses will aid in determining an astigmatism, in connection with the Inetallic plate and slit. A slipl of colored glass will be useful in _ _~._ G,TIEMANN & CO. FIG. 5. testing double images, and a few prisms are necessary to measure the strength of the ocular muscles when this is desired. The ophlthalmoscope perhaps ought now to be considl IMPLEMENTS AND INSTRUMENTS. 35 ered indispensable to the general practitioner. Very necessary also are a pair of silver lid-elevators (Fig. 6), G. TIEMANN & CO FIG. 6. and for the extraction of foreign bodies embedded in the cornea, a wire speculum, self-adjusting (Fig. 7), a FIG. 7. fine needle and a delicate spatula, spud or grooved needle (Figs. 8, 9), and a pair of delicate forceps for G.TIEMANN & CO FIG. 8. I G.TIEMANN & CO FIG. 9. steadying the eyeball are useful. The Snellen eyelid tourniquet is an almost indispensable aid in removing cysts of the lids. Fig. 10, on the next page. 36 EXAMINATION OF THE EYES. Bandaging the Eye. The ordinary bandage may consist of a piece of linen about ten inches long by two and a quarter inches in width, with a piece of broad tape at either end to pass around the head, and tie. A third tape may pass over the top of the head to assist in holding the bandage in place when necessary. Before applying, a bit of abGTIEMANN & CO. FIG. 10. sorbent cotton, anti-septic, medicated, or otherwise, should be placed over the closed eye. The compress bandage should be one and three-quarters yards in length and about one and a half inches in width, and made of linen, or, still better, fine elastic flannel. To apply it, commence above the affected eye, pass it across the forehead to the opposite side, above the ear, to the'back of the head, below the ear, then up across the affected eye, and pin it securely to the first portion upon the forehead. CHAPTER IV. THE OPHTHALMOSCOPE. IN order to see into the interior of an eye, it is necessary first of all that the interior should be lighted up. The old notion that an eye under certain nervous conditions becomes luminous from within is not correct. It can be illuminated only by light from without. The second condition necessary is, that, having thrown rays of light into the eye under examination, we should place our own eye in such a position relative to the one illuminated, as to catch the reflection of the rays of light which we have thrown in. These two conditions are absolutely necessary, and any further ones merely add to the convenience of examination or render our examination more accurate. With a bit of common windowglass we can fulfil these two conditions. Seat the patient in a darkened room with a lighted lamp by his side, the flame about on a level with the eye to be examined. This fragment of glass held in front of the pupil, and quite near the eye under examination, throws a sufficient light from the lamp directly into his eye. This fulfils the first condition. The eye is illuminated. Now put your own eye behind the glass directly opposite that of the patient, and it will catch the return rays passing from his eye through the glass into yours, and 38 THE OPHTHALMOSCOPE. you will see the entrance of the optic nerve, or optic disc as it is termed, and the vessels of the retina passing over and away from it. (See plate opposite titlepage.) The fragment of glass is in reality an ophthalmoscope, all ophthlamoscopes are merely modifications of this, and and do not differ from it in principle. It has been found more convenient, however, to substitute a mirror for the plane glass, with a small hole at its centre for the eye of the observer. The mirror may be plane, convex, or concave. A concave mirror reflects more light into the eye, and hence renders the details of the fundus more EMANN i CO. FIG,. 11. distinct. To the same end also it has been found serviceable in practice to hold immediately before the observed eye, with the left hand, a convex glass of about two inches focus. This convex lens enlarges the field of vision; and, although we get an inverted image, on the whole it facilitates an examination so much as to render its use almost indispensable in the examination of the deeper structures of the eye. There are some forty or fifty different kinds of ophthalmoscopes in use. The one most common, and to be commended, is that of Liebreich (Fig. 11), though oculists use the more costly and complicated ones of Loring or Knapp. It con 1'T1I IN E )ll'l' A iOP A.SC()i'IE. #39 is ts of a.. meitatlia I in'inor sli r itiv con.cave, about. a intch a( i a tigh th int il diaonet r1, sett in a metalltt ic fltame,, with a handlcl. whichlt p)ust.hes. into.itse.lf Iso as to be Iot mtlor.e t:han t:Wo itnches itn lenigt whien not: in lse, andt conve1t i:entlit fior. t.'ti pocket. Inll th cc'itt: o thl e miii ior Fio. 12. is an apert're one-eighlth o(f an inch ilt diametei', ndnt a;tttaclhetd to th:te l'frante of t1le n irtro( is a hingted Ib'racket to hold a small convex or cooneave lens, t:o assist. the e(ve t:f he'observter if netce(ssa',.'ie o'l j)ieet 1aiss o' c('011 vet x lens is ralther I a: tr ihan th in:e'a t i e'ioro':)l of a(ht t two( ihlf..es focus()., tand a mav be: set also in a mietaltli fiErame witt aI 40 THE OPHTHALMOSCOPE. short handle. The more elaborate " refraction ophthalmoscope" is used by oculists generally, and is represented by Fig. 12 on the preceding page. A very interesting form of instrument is the binocular ophthalmoscope, so constructed that by means of prisms we are enabled to use both eyes at once in an examination. Through this we obtain a stereoscopic view of the fundus, all its parts being brought into relief. It is easier with this instrument to determine the relative positions of opacities in the vitreous humor, or extravasations in the retina or choroid. Attractive, however, as the binocular ophthalmoscope seems to be, I find that in practice I seldom use it. It is large, cumbersome, and heavy, and requires more time for its proper use, and ordinarily, therefore, its advantages do not in practice appear to be of sufficient importance to compel its employment. Another, the aut-ophthalmoscope, is so arranged that, by an ingenious combination of mirrors, one may look with his right eye directly into his left, or vice versa. HOW TO USE THE OPHTHALMOSCOPE. In the beginning, in order to learn to use the ophthalmoscope, it is best to examine a number of healthy eyes. It is advisable also to dilate the pupil with a two per cent solution of cocaine - which will so enlarge the field of vision in a few moments as to make the examination more interesting and instructive. Cocaine is preferable to atropine for this purpose as its effect on the pupil passes away in a few hours. It must be remembered that if we use the convex object glass we get an indirect or inverted picture of the fundus, and without the interposi HOW TO USE THE OPHTHALMOSCOPE. 41 tion of the object glass we get a direct or upright image. Having seated our patient in a room from which daylight is completely excluded, with a good steady light at his left side, we take up the mirror in the right hand, put it close to our own eye and our eye to the aperture, and on a line with the eye to be examined, and distant from it perhaps eight to twelve inches. Turning the mirror slightly towards the lamp, we illuminate the eye of the patient. Already we have learned something, because all eyes cannot be illuminated,- an opaque lens, for instance, prevents it. Now, hold with the left hand the convex object glass before the illuminated eye, at the distance of an inch and a half or two inches, directing the patient to look in the direction of our left ear when we are to examine his left eye, and our right ear when we direct our attention to his right eye, - in other words, directing that the eye under examination shall be turned slightly inward so as to bring the optic nerve directly opposite or behind the pupil. To examine the region of the macula lutea the patient should look straight forward, directly at the eyes of the observer. It will be recognized as a spot slightly darker in color, with no vessels running over it. Having illuminated the fundus of the eye with the mirror in the right hand, we must be careful not to change its position while we are adjusting the convex glass held in the left hand, otherwise we shall fail to see the interior of the eye from lack of light. If the patient is myopic we gain a more distinct view by approaching our own eye a little, and if he is hypermetropic we see better by increasing, slightly, the 42 THE OPHTHALMOSCOPE. distance between our eve and his. If our own eye is presbyopic or hypermetropic we may also find it advantageous to use in the hinged bracket behind the mirror one of the little convex glasses of eight or ten inches focus which belongs to the ophthalmoscope. The convex glasses will also be found serviceable if the eye of the patient is hypermetropic. In the direct examination without the object glass in the left hand, if we desire to examine the disc or findus, we must approach our eye very near to that of the patient; but to simply test the'transparency of the media, - the lens or humors, - we place our own eye at a distance of fifteen or eighteen inches from the eye under observation. The appearance of the fundus of the normal eye differs considerably in different individuals. The fundus of the eve of a light-complexioned person is light-red, while that of a dark-complexioned one is dark-red, owing to an albundance of pigment in the choroid, and in the pigment layer of the retina. In the former, we may see many of the vessels of the choroid which give the fundus a striated appearance. In very dark eyes the choroidal vessels are invisible. See Frontispiece. The disc or optic nerve entrance appears generally, to me, of a slightly yellowish-grayish pink. In dark eyes more white and glistening, in light eyes more rosy in color. It is usually circular in form, but in astigmatism often has the appearance of being oval when it really is circular.l Its edge is sharply defined, and 1 Suppose, for instance, a case of astigmatism where the cornea is too convex in the vertical meridian. The optic disc appears oval HOW TO USE THE OPHTHALMOSCOPE. 43 ncar it may be seen occasionally a slight crescentic line of pigment. The face of the disc is more pinkish at its inner half, and where the retinal vessels emerge from it. The retinal vessels run principally upward and downward, an artery, known by its light color, and two veins running in each direction. The retina itself, in a healthy state, is transparent, and cannot be seen. Exceptionally in very dark eyes, it may be detected as a gray film, in the immediate vicinity of the disc. The physiological excavation, not unfrequently noticed in the healthy nerve disc, is spoken of in connection with pathological excavations in the remarks on atrophy of the optic nerve. Venous pulsation may sometimes be observed in the healthy eve. It is to be looked for in that part of the retinal vein between the centre of the nerve disc and its edges. It may be produced by gentle pressure on the ball of the eye with the finger. Similar arterial pulsation indicates intra-ocular pressure, and is not found in the healthy eye. The ophthalmoscopic appearance of the diseased eye is spoken in a vertical direction if we make a direct examination. In indirect examination it will appear oval in a horizontal direction. The reason of this is plain. Our convex glass makes objects appear larger if held near them, but if removed from the object beyond its focus (about two inches) we have an image inverted and reduced in size. Now, in a case like the above, the eye lends the greater refracting power to the glass in a vertical direction, and the inverted and reduced image will, of course, be reduced most in the direction of the greatest refractive power. The convexity of the glass and the cornea combined being greater in the vertical line, the inverted ima'e of the disc is reduced most in this direction. Hence it appears oval horizontally. 44 THE OPHTHALMOSCOPE. of in connection with the various affections which demand its aid for their diagnosis and intelligent treatment. I may remark here, however, on the great importance of what is termed lateral or oblique illumination in detecting diseases of the anterior part of the eye. A good rule to follow in ophthalmoscopic examinations, - one that will save time, facilitate diagnosis, and prevent error, - is to always commence the examination by LATERAL ILLUMINATION. Lateral Illumination of the eye is best conducted in a darkened room, also. The patient sits relatively to the light, as in the ophthalmoscopic examination. The convex object glass is to be held between his eye and the light, the patient facing the observer, so that a strong light is thrown obliquely on to the front of the eye illuminating the cornea and anterior chamber. We may in this way detect opacities of the lens, examine with the greatest nicety the surface of the cornea and the texture of the iris. A second convex glass may also be used at the same time to look through as a magnifying power, if desirable. DIFFICULTIES OF DIAGNOSIS IN DISEASES OF THE EYE, FORMERLY. Before the discovery of the ophthalmoscope, by Helmholtz, in 1851, very little, comparatively speaking, was known concerning the internal diseases of the eye, and the little knowledge which we possessed was very inexact. The history and progress of this kind of disease IMPORTANCE OF, TO PRACTITIONER. 45 it was of course impossible to determine with any certainty. Diseased eyeballs were rarely dissected after death; and when this was done, it yielded but scanty return for the labor. A comparison of the pathological anatomy in such an instance, with the symptoms observed during life, in an organ of which nothing objective in regard to its deeper structures could be previously determined, afforded little satisfaction, and still less serviceable information. We may say, therefore, that previous to the introduction of the ophthalmoscope, our entire knowledge, almost, of the diseases of those parts of the eye posterior to the crystalline lens was conjectural. When the cornea and the iris and the lens presented no appearances of lesion, and yet the patient's visual power was impaired, we were disposed, and it might be said perhaps that we were compelled, nolens volens, to attribute the visual disturbance to some affection of the optic nerve. In the words of another, when neither the patient nor the doctor could see anything, it was amaurosis! 1 IMPORTANCE OF THE OPHTHALMOSCOPE TO THE GENERAL PRACTITIONER. It is within a short time only that, in the treatment of general nervous disorders, the attention of the profession has been called to the importance of knowing the exact condition of what has been fitly termed the outpost of the central nervous system, - the nervous structure of the posterior portion of the eye, the condition of 1 Amaurosis sei jener Zustand wo der Kranke nichts sieht und auch der Arzt nichts. - Walther. 46 THE OPHTHALMOSCOPE. which gives, in many cases, a picture of the condition of the brain itself. The ophthalmoscope is, therefore, destined in the future to be of great service to physicians in the treatment of a large class of diseases of the brain and nervous system. Among disorders of this kind which the general practitioner is called upon to treat, and in which the ophthalmoscope has already proved serviceable are the following: meningitis, encephalitis, hydrocephalus, cerebral hemorrhage, tumors, epilepsy, insanity, locomotor ataxy, nervous fevers, and \velitis. In the optic nerve disc, for instance, we may see congestion and effusion, inflammation of substance and sheath, anemia, and atrophy. An optic neuritis is connected with meningitis of the base of the brain, with a tumor, with large hemorrhage. An atrophy of the nerve, which may be recognized as either progressive or stationary, is accompanied by disease of the brain, cerebellum, or spinal cord. In lead poisoning there has been noticed a change of color and transparency in the optic nerve disc. In the retina, we detect inflanmmations, fatty or fibrous exudations, and hemorrhages; in the choroid, loss or disturbance of pigment, hemorrhages, and effusions; and in the blood-vessels of the fundus generally are observed diminution in size, dilation, obliteration, tortuosities, pulsations, varicosities, blood stases, displacement, effusion, and rupture. In albumlinuria or Bright's disease, one may watch the changes that finally result in degeneration of the sulbstance of the retina, and defective nutrition of the optic nerve. IMPORTANCE OF, TO PRACTITIONER. 47 Chronic headache, especially when the location of the pain is unusual or seems permanently fixed, and when accompanied by vomiting, should be regarded with suspicion, and every means taken to determine the state of the brain. Severe headaches and bilious vomiting have been known to herald final disease of the brain, and amaurosis. The ophthalmoscope will sometimes be of value in enabling the practitioner to determine the significance of these symptoms, whether they are to be regarded as of cerebral or of gastric origin, or are due merely to errors of refraction or muscular insufficiency. In insanity, the ophthalmoscope has become an important agent in determining its course. Of a large number of patients submitted to examination, many have been found to present affections of the optic nerve. Dr. Allbutt, of the Leeds Infirmary, found that in fiftythree cases of that kind of insanity known as general paralysis, forty-one had disease of the optic nerve. The affection begins as a pink suffusion of the disc, and ends in white atrophy. It resembles in appearance the "red and white" softening of the bralin. Of fifty-one cases of mania, more than half showed symptoms of disease of the optic nerve, - a stasis followed by consecutive atrophy, or white or mixed atrophy. After a paroxysm, there is a paralysis of the blood-vessels and about the disc, causing hyperaemia. In dementia and in idiocy, and in insanity, from epilepsy, a large number of cases show disease of the optic nerve or retina. Thus investigations in regard to the diseases involving the brain and nervous system are greatly aided by ocular examination of the nervous and vascular tissues 48 THE OPHTHALMOSCOPE. of the eye with the ophthalmoscope. Here we see a diseased nerve, and measure with our eye the progress of the affection. It has been remarked with truth that hereafter no record of a nervous affection can be considered complete unless it gives a faithful account of the ophthalmoscopic appearance of the retina and optic nerve. CHAPTER V. REFRACTION, ACCOMMODATION, AND THEIR ANOMALIES. REFRACTION of the eye, or the refractive power of the eye, is the phrase used to express its power of bringing rays of light entering the pupil to a focus in the vicinity of the retina. Accommodation expresses the ability of the eye to increase or lessen its refractive power by means of the ciliary muscle and iris. Thus, in a state of rest, regarding a distant object, the emmetropic (normally refractive) eye needs no exercise of its power of accommodation, because the cornea and lens are precisely convex enough to bring parallel or distant rays of light to a focus on the retina. The latter is situated at a distance of about one inch behind the cornea, and the refractive power of the eye at rest is about equivalent to a convex glass of one-inch focus. But if we regard an object near the eye, the rays fall no longer parallel upon the cornea, but divergently, and of course a greater focussing power is needed to bring them to a point at the proper distance behind the lens. A refractive power, the equivalent of a one-inch convex glass, is insufficient, and the exercise of the power of accommodation becomes necessary. 4 50 REFRACTION AND ACCOMMODATION. Accommodation of the Eye is brought about by the contraction of the ciliary muscle, which causes, through the medium of the Zonule of Zinn, an increased convexity of the crystalline lens, mostly at its anterior surface, giving it a higher refractive power. This action relaxing the tension of the Zonule of Zinn, permits the lens through its own elasticity to assume a, more convex form. There are also the associated movements; namely, the periphery of the iris is drawn slightly backward, the pupil becomes smaller and is moved forward, the anterior choroid is moved forward, and there is a perceptible forward movement of the whole eyeball. CONVERGENCE, so that the two eyes may be directed to the same point, is also, in binocular vision, more or less inseparable from accommodation. DISTINCTION BETWEEN REFRACTION AND ACCOMMODATION. It is to be remarked that the power of accommodation in the eye may be entirely suspended (for instance by the instillation of atropine), and still the ref raction remain sufficient for distant vision. In presbyopia, the accommodation is much lessened in power, so that the near point for fine print may be as far as fifteen inches or farther from the eye, while the emmetropic eye is able to see the same print distinctly at three inches. The former, like the latter, has perfect refractive power for distance. In myopia, the antero-posterior diameter MYOPIA. 51 of the eyeball being lengthened, the refractive power is too great for distant objects, -the power of accommodation may be unimpaired. In the hypermetropic eye the same diameter is too short; there is a lack of refractive power, - the rays of light reaching the retina before being focussed, - while the accommodative power may be good. REFRACTION AND ITS ERRORS. Considering rays of light from distant objects, or from objects distant more than six metres or eighteen feet, as parallel rays, we may say, in general terms, that in the Emmetropic eye, parallel rays are brought to a focus upon the retina. Myopic eye, "'' " " " " " before " " Hypermetropic eye,' "' " " " " behind " " Astigmatic eye,' irregularly focussed. MYOPIA (NEAR-SIGHT). The optical defect of the myopic eye is exactly the reverse of that of the hypermetropic, -that is, its refractive power being in excess, parallel rays of light are brought to a focus before reaching the retina. This is due to the increased antero-posterior diameter of the eye, the bulging of the globe being posterior, at the entrance of the optic nerve. The retina is thus pushed too far back from the cornea and lens. This elongation of the posterior pole of the eyeball can be seen by requesting the patient to look as far inward as possible; we then notice also that the space in the orbit between the outer canthus and the globe, observable in the em 5;' IdFI.F' t iO ('. t 1. )N AND) ACCOMMOAT ('I'.)lf) ON, ettl oi:, )ic. (nort ally rt erac\-t i v), atId Osi ( iat ia ll it the ),ePmI(tvIolp)i Cl (?Ve. is c(iltm}etely filled I by tlte distendedi Fit, 18, i:o.(:'. Xclxceoptioally, IfIy)oia t iavy e ihe re islt: oif too g.rcat rcifractiol, thtie axis of thle Iee not c beig itmt st td..re 1 above esents c, lhe x F 1. 16. Fig. -14 sllows tl.he f)orl ot tin) emmi(etrpie eCe, w\hie(.}! (err.'es))ponds so pe'fect el wi th its rettfra(ctio)l th)at; pratf l TH-E CAUSE OF MYOPIA. 53 rays of light from A are brought to a focus exactly upon the surface of the retina. In Fig. 15 we have the mnyopic eve again, but being provided with a suitable concave glass, its refraction is thereby so far diminished that the parallel rays of light are properly focussed. THE CAUSE OF MYOPIA. Myopia is rarely congenital, often hereditary, and perhaps often acquired. It is possible that an hereditary predisposition to the affection may exist in those cases where it is acquired, and in which no myopic parentage can be traced. Late researches tend to show that, among school children, the myopic eyes are recruited, as the process of education goes on, mostly from those of hypermetropic refraction; that, in young children, this form of optical defect is very common, but as time goes on and the eye is used for near objects in study, and especially if the child is not robust, the hypermetropic refraction is lost and the eye becomes myopic. This change to myopia is all the more likely to occur if there is an astigmatism also. The astigmatic eye is usually weak and irritable, especially if the astigmatism is myopic. Such eyes pass directly over from hypermetropia to myopia. It is affirmed that an emmetropic eye will, in all probability, escape injury during the educational period; but comparatively few eyes can be strictly classed as such. Progressive, or acquired myopia in young people may not be directly attributable, therefore, to the process of education, although education undoubtedly encourages 54 REFRACTION AND ACCOMMODATION. and hastens its development in all those children whose eyes deviate from the emmetropic standard. Unfortunately, the greater number of eyes are found to be hypermetropic, and these pass easily over into the myopic; it is nevertheless a fact that certain conditions tend strongly to the production of myopia. I have known several students at different times in Vienna, who informed me that when quite young they saw as far as their fellows, but that after commencing their studies, and pursuing them late at night in their homes among the mountains, with no light but that of a miserable tallow candle, and sometimes even less than that, a shred of cotton in a cup of oil, a light so dim and flickering that the book must be held within a few inches of the eye, or the head be bent over so as nearly to touch the paper when writing,- after studying in this way for a few years they became myopic. We know that myopia is more common among the educated than the illiterate, and that it is usually progressive in schools from the elementary grade upward. Probably this progress is somewhat in proportion to the general health of the pupil. But it must be said also that the worst and most dangerous form of progressive myopia is oftenest met with among the illiterate. The severest case 1 have ever seen was in a young uneducated Italian here in Boston. Such cases are inherited, and are so progressive and destructive as to be called by some writers " malignant myopia. " Diagnosis. - The diagnosis of myopia is not difficult. It must not be taken for granted, however, that because a patient holds his book too near, or because he does THE CAUSE OF MYOPIA. 55 not see well at a distance, he is therefore near-sighted. Astigmatism, and especially hypermetropia, may equally produce defective vision, characterized by such symptoms. Still, no opacities of the cornea or lens being present, if the indistinctness of vision increases very rapidly as large letters are removed from the eye, we may be tolerably certain of myopia. A better test is to hold before the eyes weak concave glasses, say of thirty or forty inches focus. If the patient sees better, he is in a great majority of instances near-sighted. Occasionally, however, persons of good accommodative power see more distinctly, for the moment, through weak concave glasses, though not myopic, and sometimes when a very high degree of myopia is present, weak concaves are of almost imperceptible benefit; therefore, to make our diagnosis certain, it is better to ascertain beforehand about the number of the glass required to correct the nmopia. This may be done by finding the farthest point at which the patient can read the finest type, such as Brillia.t and if this be at a distance of six, eight, or ten inches from the eye, we may place before his eyes concave glasses of a corresponding number; if his far point is eight inches, a concave glass of eight inches focus will enable him to see well at a distance, and the existence of myopia is demonstrated beyond a doubt. Another ready and convenient proceeding for the diagnosis of either near-sight or oversight is mentioned under the head of Hypernetropia at page 68. Myopia is also diagnosed with the ophthalmoscope. For this purpose we use the erect image (simply the 56 REFRACTION AND) ACCOMM( ))ATION. mirror, without the convex object glass), and find that we can see the optic nerve disc and retinal vessels, when the pupil is large, distinctly at a short distance from the eye. On moving our head to either side, we find the image moves in the opposite direction; we obtain an inverted image of the fundus of the globe exactly the reverse of that obtained in the hypermetropic eye under a similar examination. We may also detect a myopia or hypermetropia by the use of the ophthalmoscope with the object glass. In myopia, if we increase the distance between the observed eye and the glass, the optic disc appears larger; in hypermetropia it appears smaller; in eininetropia its size remains unaffected by the movement. A two per cent solution of cocaine will enlarg(e the pupil somewhat and make these examinations easier for the physician. See page 334. Pathology. - The pathological changes in severe cases of myopia, and staphyloma posticum, and an accompanying choroiditis, consist chiefly in an atrophy of the choroid resulting from the inflammation. This occurring principally around the nerve entrance, permitting the white sclerotic to shine through, we have, as a result, a, characteristic, large, irregularly outlined crescent. The irregular deposit of pigment is owing to the same cause as are also the exudations into the vitreous, and the possible final separation of the retina to a greater or less extent from the choroid. With the choroid the retina suffers also, and finally becomes atrophied in the region of the optic nerve and macula lutea. In such cases there may be phosphenes, flashes of Tim, CIAUSE OF MYOSIA. 0T (:oloredI light;, sapet:tra, metamol1iploip)si' L as well -as ambyII opia. Bttlt ttthe albov; tliseatsed tolldit:iots tar found oniv it a higih grdX.e of mlty:ia iti adults. tMlost catse of slight,t1d tnedi t un grades. of myop ( ia aret [t ee oT serliis athtotogi'Icatl cliiaet s The'11 otrd liari sn al l wilitish cresTei:t:f s( often seen at the outer i argi t of tlh optic disct, i(dte 1to tl:t ret-:ract1io0lt or lliiinningt of sot iet (01r all of thole chlol)progress,8 1t: t unletss t;ltIh progress eontlitt.es }.beyonld adult Pfm. i. e' Fio. 17. a.e, it needI not occ asion alt A. rescent as large ats tlat' oft: - i...t after Von Jael, mi:ttt t t be.c.t18iered ratlher steriout.'lle eyebll at repl')Tresen!ted i Fig'. I1.7, from Nettleship,. sI.,ho ws "gre at elongat1ion, and a net.c'.e ss ra:i 1 vhi1lt g(trade of m yopia, ~'i'/1 UC~rrdtaecd (J W/Op)U -int st 5011111 l8 }:l ( tW meical, The treatmen' t o.f m /opia must some.time s be medical, e (s.pt'eI tilllv in the easet of weakly c1hil dren', butt more utsually opticat l and hygienic.'WhTen tlhere is consideralle miusc:ul' as t hlienoptia, if the eye is irritable, the eonjunetiva injected, th'. e op)llth'almoseoope slowing a lrvpl(erWmic(. coi(,lition of the ner've disc: with or' without staph1)ylomla postieumn, tand the patienti cotmplalinls of pain 58 REFRACTION AND ACCOMMODATION. around and sometimes in the eye, with feeling of tension and heaviness in the eyeball, the prescription of glasses should be temporarily delayed until, by complete rest of the eyes and proper remedial measures, the irritable state of the eye is removed. Gentle use of the eye douche will be found grateful, also a lotion composed of a drachm of spirits of ether nitrate to six or eight ounces of pure water, to which may be added a few drops of aromatic vinegar, the wash to be sponged over the closed lids and about the eye several times a day and allowed to evaporate. For hyperlemia of the conjunctiva a collyrium of ten grains of borax, or four grains of boracic acid, to the ounce of water may be used. Often the application of very hot water for five minutes over the closed lids, several times a day, will prove grateful. In some cases it may be wise to paralyze accommodation with atropine and allow complete rest to the eyes for some weeks. There may be indications for general medical treatment, the general health of the patient being of very great importance in nearly all cases of disease of the eye. Children with progressive myopia are rarely healthy. Rapid growth, muscular and nervous debility, frontal headache, coated tongue, capricious appetite, are often present. Spectacles. Generally speaking, no preliminary treatment is called for, and our first step is to select the appropriate glasses. They are to be selected with the greatest care. If too weak, they are comparatively useless; if too strong, a positive injury. The degree of myopia is determined by the negative focus of the glass which neutralizes it. If a patient reads No. 1 of the THE CAUSE OF MYOPIA. 59 test type at six or eight inches, his myopia is one sixth or one eighth. A concave glass of six or eight inches focus should, theoretically speaking, enable him to read No. 20 at twenty feet, and to see well at a distance. Practically, however, we find it necessary to prescribe concave spectacles rather weaker than this. If the myopia is one eighth, vision will be most perfect through glasses of one ninth or one tenth; which of the two numbers will prove best is to be determined by trial. The reason of this non-correspondence of the number of glass to the degree of myopia is this: the patient's far point being eight inches, the visual axes were converged for this distance, and with convergence of the eyes is associated accommlodation (an increased convexity of the crystalline lens); in looking at a distance through the i)rescribed glasses, the visual axes are of course parallel, and there being no accommodative power (increased convexity of the crystalline lens) to overcome, the glasses should be proportionally weaker. The proper glass to enable him to read music or small print at twenty-four inches would be of about twelve inches focus. The formula would be: - + -1 =-1-2. The patient's power of accommodation will influence greatly the choice of spectacles. When little or no accommodative power exists, as is often the case in a high grade of myopia, spectacles may be given which completely neutralize the myopia and entirely supplant any little accommodative power present. When only a tolerable power of acconmmodation is found, it is advisable to prescribe glasses which partially supplant it. Thus if our patient has a myopia of one eighth, and finds glasses of one ninth best, 60 REFRACTION AND ACCOMMODATIO(N. if his power of accommodation be one twelfth, he will, through these glasses, be obliged to use his whole power of accommodation for reading at a distance of twelve inches. This is not safe, lest symptoms of fatigue supervene, his eye become irritable, and his myopia be increased. He should, therefore, be provided with weaker spectacles for reading; concave glasses, for instance, of sixteen or eighteen inches focus, by diminishing but little the convexity of his crystalline lens, enable him to see easily at ten or twelve inches, and tolerably at a short distance beyond. He should therefore, like the imyope without accommodation, provide himself with two pairs of glasses, one for reading and one for distance. If perfect or normal accommodation is present, as is sometimes the case in the slighter forms of myopia in young persons, a single pair of glasses which neutralize the near-sight may be worn for both far and near vision. As a rule, however, it is prudent to prescrii e for near objects concave spectacles which only partially neutralize the myopia, and enable him to read comfortably at fourteen or sixteen inches. Rules are often, however, of little practical service. The myopia must be corrected by suitable glasses whether their strength correspond or not to the apparent degree of near-sight. Frequently very strong glasses will be necessary for distant vision, and the patient will find it convenient to carry eyeglasses to use temporarily before his spectacles. These eye-glasses must, of course, be concave and of just the power to supplement the spectacles sufficiently to neutralize the myopia for distant vision. When the myopia is slighter than one fourteenth or one thirteenth, THE CAUSE OF MYOPIA. 61 fine print being read easily at fourteen inches, spectacles need not be prescribed, but simply the proper eye-glasses for distant vision. The chief danger in the selection of spectacles is that of getting them too strong, and so overtaxing the eyes for near objects. De Wecker believes the great prevalence of myopia in Germany to be due partly to wearing too strong glasses. I believe it may be due principally to the peculiar text in which their books are mostly printed. The sharp and accurate vision necessary to distinguish the letters requires the text to be brought too near the eye, thus favoring the habit of short-sight. Spectacles, therefore, should not be bought at random of opticians or itinerant venders, but should be prescribed by a competent physician or oculist. When one eye is myopic and the other hypermetropic, the more serviceable eye should alone be provided for. If we prescribe a concave for one and a convex glass for the other, the former diminishing and the latter magnifying objects, it will be difficult to fuse the different sized images on the retina. Actual trial, however, is the best method of determining these matters. The best rules have their exceptions. I have a patient whose right eye is myopic and astigmatic, and whose left eye is hypermetropic. For the first he wears an eighteen-inch concave cylindrical, and for the second a sixteen-inch convex spherical glass, and with these reads more comfortably with both eyes than with either eye 1 De Wecker's rule is very good in doubtful cases: " Eviter de donner dans l'hypermetropie des verres trop faibles, et d'en prescrire de trop forts dans la myopie." 62 REFRACTION AND ACCOMMODATION. alone. In non-diseased eyes the phosphenes, spectra,'flashes of colored light, and like phenomena arise from over-sensibility of the retina, and generally disappear under treatment of the irritable condition of the eye. If they do not, like muscae volitantes and scotoma, they will be rendered less apparent and troublesome by the use of colored glasses. After prescribing with the greatest care the proper glasses, it is necessary in the progressive myopia of young people to enforce strict hygienic measures. Our patient should not work continuously at near objects, but should rest a short time at intervals of a quarter or half hour, and always whenever the eyes feel in the least fatigued. He should never work or read with the head bent forward, as this promotes intra-ocular congestion. The light should fall upon his work from behind, so that the eye may be protected from glare. Children's school desks should, therefore, be made sufficiently high and sufficiently sloping, and be placed, as regards light, to fulfil these conditions. In the myopia of children, enforced rest of the eyes will often produce very great improvement in vision; that is, the grade of the myopia is improved. The inproved sight is apparently not wholly due to the removal of the slight tension of the ciliary muscle coimmon in these cases, as the paralyzation of the muscle by atropine produces an effect considerably less than the final effect of complete rest. Nor is it due to the curative effect of rest on the amblyopia. Often no amblyopia is present. I attribute the improvement to a change in the shape of the globe due to an exclusive THE CAUSE OF MYOPIA. 63 use of the eye for distance. See page 49, Accommodation of Eye. We should prescribe, in these cases, daily use of the eyes for distant objects in the open air. In very high degrees of myopia, such as one fourth, one third, or one half, even if no amblyopia be present, we cannot expect the patient to read large print through his glasses at a point as distant as a normal eye would do it. The powerful concave glasses diminish the size of the image too much. Very strong concaves are also inconvenient to the wearer, by compelling him to move his head always in looking to the right or left. His glasses are so deeply hollowed that he must always look through their centre, or they produce the effect of prisms or decentred glasses. Finally, it should be remarked, that in a certain number of cases of accommodative asthenopia in slightly myopic young people, it may be advantageous to prescribe convex glasses for near work. Even in cases where concave glasses are worn for distant vision, I have found weak convex glasses necessary for the eyes in reading. Such cases are exceptional, but they occur. The same is true also in myopic astigmatism of a low grade. We find that for reading, a weak convex cylindrical lens is best; while for distance, a concave cylindrical is required. I may add here, that in high grades of myopia there is frelquently an astigmatism also, and that what we at first take for an amblyopia may be remedied, to a certain extent, by proper cylindrical glasses. Many nvmopes, therefore, when the myopia is considerable, require a combination of cylindrical and spherical concave glasses. And not unfrequently there 64 IEFRACTION AND) ACCOMMODATION. is insufficiency of the internal recti requiring the comb)ination of prisms, base in, also. The power of convergence is not infrequently im — paired in myopia. This need not necessarily be due to weakness of the internal recti muscles but rather to a lack of ability in the muscles to work together so as to converge the eyes for the proper distance to give easy and distinct vision. The recti interni may also be weak. See Muscular Asthenopia, page 84 et seq. Finally it may be stated that recently, Fukala reports operations for discission of the lens in twentythree cases of very high grade of myopia with excellent results. Absorption of the lens made the refraction emmetropic, hypermetropic, or less myopic, and greatly lessened the amblyopia. In one case vision was raised from one tenth to one half, in another from one twentyfifth to one half.1 HYPERMETROPIA AND ASTHENOPIA (ACCOMMIODATIVE). Hypermetropia, as we have already seen, is that condition of the eye in which its antero-posterior diameter is too short in comparison with the refractive power (convexity) of the crystalline lens and cornea. The rays of light consequently reach the retina before they are brought to a focus, forming circles of diffusion, and vision is indistinct. A convex glass, or spectacles, by supplementing the refractive power of the natural lens, enables the patient to focus the rays of light upon the retina, precisely 1 Ophthal. Review, vol. ix. p. 304. I:tYPEl'iMEtA RIO.l'IO 1'A ANI) ASTIIENO()IA. 6(5 as in presb)yopia. In presbyIoptia, however, ralys of light from a distance -that is, wllat are termedp parallel rays. a.... re broughtt to a focut s o the retina without the use of accomtlnodat int. g pol wer; ( wh i le, in hyperlmetroplt ia, the exercise of this lotler' is alwt-itays necessary, even for distant vision, and, in the higrher grades of the aItectiolt, ColV.X glasses atr t lsto necessarty fo'r all distatnes. A. ltyperlt l opict': eye is generalIly sma llelr in all its i mnsi onls. ts t tlhn tle entelletrop'ie or nor ma 1ll re{fract i tand is usually cong ntit Ial ttand hereditary. Ti'is fo:)m of ple:,rttinet rotl'pia.a is somne,11titmes c(:alled{ a!ial in distilcltion, to a folrm wht ici tt is (occ.asiontaliy II me~ i:ti it th illt d,e to: ant ilsl0tiicitent ratr of rthe ref'ract:i e medi a. and called cutrvatare il'yle'lmf tropl:ia.' lThe t same.li is true of my:ptia whlicth, usnuall axial, maty exce' 1t iolnt lly btItt ctlurvattture intopia: ctlt.1atsed ity exeessi ve: ci(.trvature - of the refIt racttivt:. ntmedti a.'it' 1.8,tt albove, is intlenled to repiretsent. n etl.vealt II of the tyliev me t:ropi c formi t he para:llel I rays of li tlht frot A. tare seen to reach: l the retina befol:re tbein, lb'roIIuht to: foteus. Sutch t eNye mit tightl perhaps fot>tI. s parallel rays by lte exercise of its \owert olf acomt(.modation; butl if the rattnte of,ac.coitmoda tiion weire litmlited, or the ograde 1) -W ~ 7m- A. V ---— _' —--— 1 | v **rt z -5 z -rais — -i e.-' _, R -; _~~~~~~~~- t- _ _ - - - z: > e> age ad l...... t* _ ~~~ ~~ ~~ Ad ^ BOX +w ~~~- rfi DIAGNOSIS OF HIYPERMETROPIA. 67 that a change to weaker glasses may after a time, become expedient. Hypermetropia is divided by Ionders into facultative, relative, and absolute. Facultative is the slightest form, where the patient accommodates readily for all distances; presbyopia occurs rather early, and then asthenopic symptoms are apt to occur; while, in Relative hypermetropia, although the patient can accommodate so as to see well at all distances, yet this is only accomplished through great efforts of accommodation, and by converging the optic axes strongly at the same time. Such persons are almost certain to become asthenopic. Absolute hypermetropia is a condition of the eye in which the patient sees distinctly only by the aid of convex glasses. Without spectacles no effort of accommodation, however great, will suffice to focus rays of light upon the retina. A hypermetropic refraction is caused in the emmetropic eye after the loss of the lens in extraction, and also in aged people from a high grade of presbyopia. DIAGNOSIS OF HYPERMETROPIA. Let the patient look at No. 20 of the test type at twenty feet, and if his vision is improved or not lessened by looking through convex glasses of thirty or forty inches focus he is hypermetropic. These glasses would not render the vision of an emmetropic eve more acute. But it may happen that, although slightly hypermetropic, he does not see as well through the convex 68 REFRACTION AND ACCOMMODATION. glasses, or he may even see as well, through concave glasses of thirty or forty inches negative focus, as in myopia. He is not myopic, however; but in looking through the concave glasses he involuntarily exerts all his power of accommodation; and when this power is considerable, he overcomes, for the time being, his own as well as the additional hypermetropia caused by the concave glasses. Slight tension of the ciliary muscle might also cause an apparent myopia. Ordinarily, however, we find that a weak convex glass improves vision; if it does not, we may try the effect of paralyzing the accommodation by the instillation of atropine. We can then determine the whole extent of the hypermetropia, both latent and manifest. If after an -hour or two we try our convex glasses again, we may find that whereas, previously, he could only see well through convex thirty, he now sees best through convex twelve or fifteen. His manifest hypermetropia was only one thirtieth; but his latent, being added, gives him really a hypermetropia of one twelfth or one fifteenth. The hydrobromate of homatropine in one per cent solution may be used in these cases generally, as its unpleasant effects on accommodation pass off in a day or two. Another, and very simple test, for anomalous refraction, without the aid of glasses, is mentioned under Amblyopia. We may diagnose the affection also by means of the ophthalmoscope, using the direct image. With this we see the details of the fundus at a little distance, as in myopia, only in this instance we get our image uninverted. A movement of the observer to the right or left THE OPHTHALMOSCOPE IN MEASURING AMETROPIA. 69 will produce a similar movement in the image, and not the reverse as in myopia. Approaching nearer, we find the field of vision unusually large, and the optic disc apparently small, but distinct, just the reverse of what we notice in myopia. In myopia, however, we may render the fundus of the eye distinct by using a concave lens in the hinged bracket behind the mirror, and in hypermetropia we may make the fundus more distinct by the same use of a convex lens. In this way, by the direct or upright image, we may not only detect the existence of an optical defect, but determine its nature; and the number of the lens plus or minus, our own eye being emmetropic or made so by a proper glass, will give us the measure of the manifest and sometimes the total hypermetropia, or myopia. The newest forms of the ophthalmoscope have a large number of lenses so arranged as to be quickly available in diagnosing and measuring ametropia. But the accurate use of THE OPHTHALMOSCOPE IN MEASURING AN AMETROPIA requires practice. The accommodation of the patient must be relaxed, and if the dark room in which the examination is made be sufficiently spacious, or if, as in my ophthalmoscopic room, a dark curtain be arranged on the wall opposite the patient, this may be accomplished; otherwise atropine is necessary. The observer must also relax his accommodation. Then, the convex lens, beginning with the weakest that enables the observer to see the region of the macula lutea or some of the retinal vessels running from the edge of the optic 70 REFRACTION AND ACCOMMODATION. disc most distinctly, is supposed, if the defect is a hypermetropia, to give its measure. In the same way, using concave lenses, the degree of a myopia is determined. The optic disc is not available when strict accuracy is desired, as, not being at the fovea centralis, it cannot be at the same distance from the centre of the cornea. In myopia it is sometimes anterior to the macula. As an aid in determining and confirming, in connection with other tests, the existence of optical objects, the ophthalmoscope used in this way is convenient. This method of measuring optical defects is good practice for oculists, if for no other reason than that it breaks into their routine habits of diagnosis. The shadow test will also aid in determining an error of refraction. The light is thrown into the eye by the usual concave ophthalmoscopic mirror from a distance of about four feet. It should be shaded from the patient, and may be at the side or just over his head. The room must be darkened so that no object in front of the patient shall hinder the more or less. complete relaxation of accommodation. We now notice, in moving or rotating the mirror slowly on its horizontal axis, whether the red reflex in the pupil moves with the mirror in the same direction, if so we have a myopia. If it moves in the opposite direction or against the mirror we have a hypermetropia, a slight myopia, or emmetropia. By putting trial spectacles on the patient we may determine approximately the degree of myopia or hypermetropia. If myopia, the weakest concave lens before the eye that reverses the movement of the reflex gives us the meas THE OPHTHALMOSCOPE IN MEASURING AMETROPIA. 71 llre of the error of refraction and indicates the proper glass for its correction. Similarly, the weakest convex lens which reverses the movement of the reflex gives us nearly the amount of hypermetropia. In the latter test the convex glass indicated will be somewhat too strong, and in all cases, nearly, a more correct estimate of the degree of refractive error will be obtained by the use of a iydriatic. The direct method with the ophthalmoscope as given at page 69 is, I think, more certain and more practical. I have assumed in the above, that the observer uses the ordinary Liebreich concave mirror. If a plane mirror is used, the movements observed will be exactly the reverse; that is, in myopia against the Inrror, in hypermetropia and emmetropia with the mirror. In slight myopia, - that is, of one dioptric, or less, -the movement with either mirror is as in emmetropia. Spectacles for distance should not be prescribed for hypermetropia, if the patient can see well and without fatigue, as after being used for distant vision they become indispensable for all time; but for near vision, they should be ordered the moment asthenopic symptoms appear. In higher grades of the affection, where vision for all distances is imperfect, glasses which correct the manifest hypermetropia may first be worn; and later, when the eyes become accustomed to these, stronger ones may be prescribed, if necessary, so as to correct more or less of the latent defect also. Exceptionally, such patients require the stronger glasses from the first and reject the weaker ones. 72 REFRACTION AND ACCOMMODATION. ACCOMMODATIVE ASTHENOPIA may be defined as a condition of the eye in which it cannot be used continuously for near vision, even in the best light, without pain and confusion of sight, although for the first moment the patient sees with ease and distinctness. The eyes are sound in appearance, in movement, in visual form, in convergence of visual axes, but they rebel against all use, however moderate. After the least service upon near objects, they feel fatigued, full, hot, and sometimes become quite painful, the pain extending to the head, or following the branches of the fifth nerve. It is not unusual for asthenopic eyes to show a slight hyperemnia of the conjunctiva, and in the neurotic we often notice an enlarged and rather sluggish pupil. The dilated pupil is not due to local disease, but to reflex disturbance of the ciliary nerves from irritation of the sympathetic. In these cases we find spinal irritation or disturbance of the uterine or digestive functions. The dilatation of the pupil is, when it exists, an additional hindrance to distinct vision for near objects, by admitting too much light and too many lateral rays, and by increasing the circles of diffusion. As the rays reach the retina before being focussed, the object is not pictured upon the retina at a single point, but by a number of conical pencils of rays in the form of circles which, overlapping each other, render the image blurred. Sometimes there is to be observed a hyperasmic condition of the optic nerve disc and retina similar to the hyperaemic state of the conjunctiva. In rare instances, ACCOMMODATIVE ASTHENOPIA. 73 the optic nerve itself appears to be the principal seat of the pain. I can recall instances where the least exercise of the eye produced deep-seated pain of the globe. Formerly, asthenopia was looked upon as a grave affection, and as a probable precursor of amaurosis, or some other disease fatal to sight. It is sometimes a symptom of general debility, arising from exanthematous or febrile affections, from overwork, mental troubles, dissipations, abuse of the eyes, and like causes. All these, however, only express the occasional, or exciting cause. The primary cause is usually to be sought in a more or less faulty state of the refraction, the consequent fatigue of the ciliary muscle, and the resulting irritable condition of the eye. Some hypermetropic eyes escape asthenopia for a time from having been originally endowed with a wide power of accommodation. A youthful normal eye is sometimes able to read the finest type, No. 1, from three up to eighteen inches; while another may be able to read it only from four up to twelve inches, —the first showing an accommodative power of considerably greater range than the second. Moreover, according to Von Graefe, there is considerable difference exhibited by different individuals in the impunity with which they may exert a great part of the accommodative power at their disposal. Some persons, for instance, are unable to use one half of this power for any length of time without injury, while others use more than three quarters without fatigue. In the first, there appears to be a lack of energy in the ciliary muscle; while, in the second, it is unusually vigorous. Hence it may follow that the more or less perfect opti 74 REFRACTION AND ACCOMMODATION. cal construction shall in some instances give but an imperfect indication of the serviceableness of an eye for fine work. The working power of the eyes may also depend, to a certain extent, upon the equilibrium of the external ocular muscles. See page 84 et seq. TREATMENT OF ACCOMMODATIVE ASTHENOPIA. The first and most important indication in the treatment of accommodative asthenopia is to relieve the painful and overworked ciliary muscle by supplementing the refractive power of the crystalline lens with suitable convex glasses. Sometimes, when the affection is of long standing, and the whole eye seems to have been reduced to an extremely irritable and sensitive condition, we may have considerable trouble in finding glasses that can be worn with comfort; and yet, if the eyes are to be used at all, the help of glasses is absolutely required. It may be necessary in those cases to completely paralyze the accommodation for some weeks by the instillation of atropine, simply for the purpose of resting the eye. For the selection of glasses, I generally determine the amount of manifest hypermetropia, by permitting the patient to look at No. 20 print at a distance of twenty feet, or where an emmetropic eye would see it with distinctness. Then I find the lowest convex glass through which he can read the print, and this determines the degree of manifest hypermetropia. Having determined this point, I prescribe, if the hypermetropia is thirty-six, a convex glass of thirty inches focus; if it is fifty, glasses of about forty inches focus, and so onl. TREATMENT OF ACCOMMODATIVE ASTHENOPIA. 75 De Wecker advises that the manifest and about one fourth of the latent hypermetropia should be corrected by the first glasses presented. In practice, however, it is often necessary to begin with a weaker glass (D - 0. 75 or + 48), and then change, after a few weeks, to those of a greater refractive power, in order to complete the cure. But the strength of the convex glasses will depend greatly on the amount of latent hypermetropia, and this is to be determined with the ophthalmoscope, or by atropine and the test types. We must remember that in myopia the convergence is always in excess of accommodation, while in hypermetropia the accommodation is in excess of the convergence. In neither optical defect do the ciliary and the internal recti work together harmoniously; hence, probably, a great part of the discomfort. Sometimes, in asthenopia due to facultative hypermetropia, the glasses, after having served to cure the asthenopic symptoms, may be discarded. The systematic use of the glasses after the Dyer method is usually advisable. Thus, we take as a starting point for the exercise of the eyes in reading, that period of time asserted by the patient to be the longest that he can use his eyes without fatigue. It may be one minute or less, or it may be five or ten minutes. He is then instructed to put on his glasses and read the given time through them three times a day, adding one minute to this time each day, until perhaps a half-hour is reachedo Then two minutes a day may be added; and when the patient can read from one to two hours at a sitting, without fatigue, the cure is complete. Reading by artificial light may finally be practised in the 76 REFRACTION AND ACCOMMODATION. same way. The reading matter should not be of too absorbing a nature, and the patient should be made to understand that the sole purpose of the reading is for the hygienic exercise of the eyes. If the asthenopia is clearly the result of general debility, due to diminished energy of the muscular system generally, and the hypermetropia is slight, or wholly wanting, it is possible that the restoration of vigorous health through internal medication, generous as well as prudent dietetic regulations, or change of air, with systematic exercise of the eyes in reading as just described, may cure the asthenopia without the necessity of a resort to spectacles at all. I have found the Dyer method alone - that is, without glasses - sufficient in a certain number of cases. ASTIGMATISM. This is an anomaly of refraction dependent generally on a lack of symmetry in the different meridians of the cornea. It was noticed by Young, in 1793, but first correctly explained by Donders, who published a work on the subject in 1862. Previous to the researches of Donders, there had been recorded less than a dozen cases for seventy years; since his investigations, cases are recorded daily. Astigmatism is congenital, or may be acquired from wounds or ulceration of the cornea. It is divided into the regular and the irregular. Regular Astigmatism is called simple when one meridian of the cornea is emmetropic and the opposite myopic or hypermetropic. It is compound when both meridians are myopic or hy DIAGNOSIS AND TREATMENT. 77 permetropic, but in different degrees, as if, for instance, in the vertical meridian the cornea were sufficiently convex to make a myopia of one eighth, while in the horizontal line it might be only convex enough for a myopia of one sixteenth. In rare instances there is mixed astigmatism, one meridian being myopic, the other hypermetropic. Irregular Al.ytii/mati~)m is due to imperfections in the structure of, or to partial dislocation of, the lens, or to its partial opacity. It is found also in conical cornea, and results from ulcerations of the cornea, and occasionally from irregularity of its surface after cataract operations. In these cases the meridians of greatest and least refraction are not at right angles to each other, and this form of astigmatism is rarely benefited by glasses. Lately, however, conical or cylindroconic glasses are said to have proved quite useful. DIAGNOSIS AND TREATMENT. To determine whether a patient is astigmatic, we have only to place some well defined lines running in vertical, oblique, and horizontal directions before him at considerable distance, - perhaps thirty feet, - and then gradually approach them so as to find if, at any distance, one set of lines appear clear and the other indistinct. If such a point can be found he is astigmatic; if not, we are obliged to refer his defective vision to some other cause. See test type, page 348. We must bear in mind that no eye is perfectly symmetrical in form, and so we may expect to find that vertical and horizontal lines will not be seen always with 78 CE'REFRACTION AND ACCOMMODATION. equal distinctness; but usually this asymmetry is so slight that no annoyance in vision is occasioned. It is well to begin the test of imperfect vision through spherical glasses, and finding that these do not render vision sufficiently acute, we may be quite sure that we have a case of astigmatic refraction. IHaving determined the existence of astigmatism, if we permit the patient to hold a metallic disc before the eye, in which there is a slit of about a line or rather less in width, and rotate it until it comes opposite the elmmetropic meridian of the cornea, so that rays of light are received by the eye through this meridian alone, he will see distinctly, reading No. 20 at twenty feet. This supploses a case of sim ple astinmati.sm, one meridian of the cornea being n(ormalll refractive or eimmetrlopic. To neutralize this Castigmatismi and render vision acute we have only to prescribe weak concave or convex cylindrical glasses. CYLINDRICAL GLASSES are segments of a cylinder; whereas ordinary glasses are segments of a sphere. A concave spherical glass, for instance, increases in thickness from the centre in all directions. A concave cylindrical glass, held with its axis in a horizontal direction, is eqlually thin throughout in its horizontal plane, but in its vertical plane increases in thickness from the centre like a. spherical concave. Those rays of light which strike a, cylindrical lens at right angles with the plane of its axis are refracted, and those which strike in the plane of its axis are not refracted at all. Cylindrical glasses are, there CYLINDRICAL. GLASSES. 79 fore, unlike spherical, to be rotated before the eye until the plane of their refraction comes opposite that plane of the cornea which requires it. In compound astigmatism we proceed to determine first, how much we can improve vision by the ordinary glasses, convex or concave. Suppose it a case of myopic astigmatism, and we find sight best through a spherical concave glass of one twentieth. We then select a weak concave cylindrical glass, and placing it before the other, allow the patient to look through both, rotating the last until its axis is in the right direction. If it proves too weak we try others. We may determine also, in advance, the number of the cylindrical glass required, with tolerable exactness by noting the different strength of two glasses, through one of which horizontal lines are best seen, and through the other of which vertical ones are plainest. Take the two letters on the next page made up of horizontal and vertical lines. A. sees N blackest, but with convex No. 15 sees Z blackest. With cylindrical convex No. 15 axis vertical, his astigmatism will be corrected. B. sees Z blackest through No. 60 concave, and N blackest through No. 20 concave. Then - 10 60- 3O —-. A cylindrical - 30 glass with the axis horizontal would neutralize his astigmatism. 1 A concave glass is designated by the sign —, and a convex by the sign +; s. spherical; c. cylindrical;, combined with. Hence, + 1.5 s., +.75 c. axis vertical Left, means the prescription for the left eye of a spherical convex lens of one dioptric and a half, in combination with a convex cylindrical one of three quarters of a dioptric. Or, under the old enumeration, a spherical No. 24 with a cylindrical No. 48, the axis of the latter vertical. C~tO AND ACCO. wcow —-- - I MIXED ASTIGMATISM. 81 A color test is recommended by Green, of St. Louis. Bright red and blue, or other shades of these colors, rendered brilliant by transmitted light, as when hung at a window, are most practical. The colors are arranged in radiating lines. I have mentioned also a simple test for astigmatism under Amblyopia. MIXED ASTIGMATISM. This form may require by-cylindrical glasses for its correction. A plano-cylindrical convex glass for the hypermetropic meridian, and a plano-cylindrical concave glass for the myopic meridian of the cornea are to be selected and put together, their axes at right angles, then rotated before the eye until their best position is found. Or the defect may be remedied by a combined spherical and cylindrical lens, as shown below. A mixed astigmatism may be quickly diagnosed by the use of the stenopaic slit. Placing the slit before the eye vertically, or in that direction in which by the aid of spherical glasses the lines appear blackest, we determine the nature and extent of the optical defect in this meridian of the cornea. Let us suppose, for instance, that we find a spherical convex glass of two dioptrics (eighteen inches focus) gives the best vision in the vertical meridian, and that a spherical concave of one dioptric (thirty-six inches focus) is best for the horizontal meridian. We may correct this defect in two ways. First, we select a cylindrical lens + 3 D, and place it before the eye, its axis horizontal; this overcorrects the hypermetropic astigmatism by one dioptric. We then put with this lens a concave spherical 6 82 REFRACTION AND ACCOMMODATION. of one dioptric. This corrects the myopic astigmatism, and also reduces the convex cylindrical of three dioptrics to a lens of two dioptrics, just what the optical defect demands. Or, we may make use of a convex cylindrical lens of two dioptrics, its axis horizontal, combined with a concave cylindrical lens, its axis vertical. The latter course is the one that I generally adopt. Astigmatism may also be diagnosed with the ophthalmoscope, as mentioned in the chapter preceding, ( FIG. 20. FIG. 21. The optic disc in astigmatism, seen The same disc seen by the direct by the indirect method (reversed method (upright image). After Netimage). tieship. the disc appearing oval instead of circular. With the upright image it may be approximately measured. We find the lens which, placed behind the hole in the mirror, gives us most distinctly a vessel running in one direction, then replace this lens by one which gives us the most distinct view of another vessel running in an opposite direction. The difference in the power of these two lenses is the measure of the astig MIXED ASTIGMATISM. 83 matism. Similarly by the shadow test (see page 70), if we note the strength of the lens before the eye of the patient that reverses the direction of the reflex or shadow in one meridian, and then the lens required to reverse the shadow in the meridian at right angles to the first, the difference in strength of the two lenses will give an approximate measurement of the degree of astigmatism. The curve of the cornea sometimes changes perceptibly from pressure of the lids and external muscles of the eye. The degree of astigmatism is also varied more or less at different times by the exercise of the power of accommodation. Astigmatism uncorrected by glasses may, of course, give rise to accommodative or a mixed form of asthenopia. It is indeed a very frequent cause of painful asthenopic symptoms, and in such instances requires the corrective glasses to be selected with great care and accuracy. Hypermetropia with astigmatism, in young persons, is supposed to pass over frequently into myopia. In view of this it may be said that astigmatism is, in early life, a most serious optical defect, and that its subjects, like those that are myopic, should be carefully guarded during the educational period. The later the earnest study from books begins, in the life of children with these errors of refraction, the less probability of harm to the eyes. If school life, or protracted reading, writing, and drawing, were never begun before the age of eight or ten, weakness of vision would notably decrease. In the case of school-children, therefore, whenever there is a doubt in regard to the optical condition of the eyes, it is the duty of the family physi 84 REFRACTION AND ACCOMMODATION. cian to advise that they should be examined by a competent ophthalmic surgeon. MUSCULAR INSUFFICIENCY. LACK OF MUSCULAR EQUILIBRIUM. MUSCULAR ASTHENOPIA. DYNAMIC SQUINT. This condition is due to weakness of an external ocular muscle, or to an increase of tension in the opposing muscle; the result is a lack of muscular equilibrium which sometimes gives rise to asthenopic symptoms and especially to headaches. Exceptionally, a number or all the ocular muscles appear to be weak. Errors of refraction, a neurotic temperament, or an exhausting occupation or illness are apparently the cause of this condition. [When all refractive errors have been corrected, and even in cases in which the refraction has always been normal, we occasionally meet with patients who still find difficulty in using the eyes, and who complain of soreness of the eyeballs, headache, and a strained, tired feeling when the eyes are used for any length of time at close work. Frequently more pronounced nervous symptoms are present, nausea, dizziness, insomnia, pain in the spine, or general nervous exhaustion. The tenotomy, especially of the upper or lower muscles, should never be attempted by one not skilled in ophthalmic surgery, because of the danger, in such nice re-adjustments, of over-correction. Injudicious tenotonly in chorea and epilepsy has given warrant to the severest criticism of conservative surgeons; but while it is too early to determine the full value of this opera MUSCULAR INSUFFICIENCY. 85 tion, it is beyond question that in certain nervous diseases, even chorea and epilepsy may be influenced by imperfect co-ordination of the eye-muscles; and while it has long been recognized that nervous diseases not infrequently affect the eyes, it is a fact, becoming daily more emphasized, that we may trace the origin of many baffling nervous derangements directly to eye-strain. The nicest discrimination is necessary, therefore, in these cases, in locating the exact relation of cause and effect. There can be no absolute standard of the strength of the muscles of the eyes, as variations will depend upon the age and general physical condition of the patient; but it has been found that, as compared to its antagonist, each muscle must have a relative strength that can vary only within narrow limits. If, for example, the internal rectus is able to overcome a prism of 40~, the external rectus should overcome a prism of not less than 6~. The ratio is about 6 or 7 to 1. If any one of the external ocular muscles is disproportionately weak, it may be impossible to use the eyes without either local or general discomfort. The method of testing the eyes in these conditions, while simple, requires patience and care. A candle flame at a distance of twenty feet is the object usually chosen. Now if a prism of sufficient strength were placed before the eye, double vision would be produced. In testing the strength of any of the straight muscles of the eye, prisms of increasing strength are placed before the eye, the edge towards the muscle whose strength is to be determined, and the strongest 86 REFRACTION AND ACCOMMODATION. with which single vision can be retained will measure the strength of the muscle. In manifest weakness of one or more of the muscles, the cause, if possible, must be found. It may be dependent upon general constitutional weakness, or may follow any exhausting illness, but more commonly it is the result of protracted eye-strain. Treatment. If muscular weakness is simply a reflex symptom from ovarian, rectal, gastric, or spinal irritation, the original disturbance must, of course, first be determined and corrected. If, however, nothing points to any such possible cause, or if, as sometimes happens, the asthenopia persists after the possible cause has been removed, the attention must then be directed to the eyes. It will frequently be found that the refraction is imperfect, and the adjustment of suitable glasses will often strengthen the atonic muscle by removing the strain upon which the weakness was dependent. But in a certain proportion of cases, the insufficiency of the muscle will be the only defect apparent, and our efforts must then be directed towards a restoration of the normal balance. This may sometimes be done by a system of ocular gymnastics. Prisms which require some effort to overcome are employed for a certain length of time daily, until the weakened muscle gradually regains its strength. A more satisfactory method will be found, however, in the use of weak prisms placed to relieve the strained MUSCULAR INSUFFICIENCY. 87 muscle and which may be worn continuously. Noyes has found in a large experience that many permanent cures may be made in this way. Having exhausted other methods of treatment, -operative interference may be considered, and the tendon of the muscle which is disproportionately strong may be partially or entirely divided. Before determining upon this method of procedure, the diagnosis must be verified by most careful tests. Ordinarily, tests may be made as already described; but before venturing upon a tenotomy the relative strength of the muscles should be ascertained beyond question, and an instrument of precision is valuable. Stevens has devised such an instrument, which he calls a phorometer. It consists of an upright supporting a cross-bar; upon the latter is a spirit-level, which makes it possible to obtain a perfect horizontal. In a sliding groove on the cross-bar are placed prisms with the bases out, and of such strength that double images are obtained. If the head of the observer is held erect, and the eyes are properly placed, these double images should appear on the same plane. If there is a difference in the height of the images, it will indicate a difference in strength or position of the corresponding vertical muscles, and the difference may be measured by another prism held with the base up or down until parallelism is restored. In a like manner a lateral divergence is shown. A prism is placed with the base up or down upon the phorometer, and when the muscles co-ordinate, the double images will lie in the same vertical meridian. 88 REFRACTION AND ACCOMMODATION. If one should deviate to one side or the other, the degree of prism which will again bring it in line, will indicate the proportion of cases of severe functional nervous disease. A surgical restoration of correct muscular balance is followed by brilliant results. - F. P. L. ] For testing the equilibrium of the external ocular muscles I find the simple glass rod of Maddox useful and sufficient in ordinary cases. The rod is to be one fourth of an inch in diameter, and may be three or four inches in length for convenience in handling. Held vertically before the pupil of the right eye, let us say, it changes the form of the gas or candle flame, which is twenty feet or more distant, into a fine horizontal line. This line should pass directly through the flame as seen with the other eye at the same time. If the line passes over or below the flame, then the line of vision with the right eye is below or above that of the left. When the rod is held horizontally before the eye, it changes the form of the flame to a vertical line. If this line is seen with the right eye at the right of the flame, the line of vision tends outward, there is weakness of the external rectus, or what practically produces the same effect, too great tension of the rectus internus. If the fine line seen with the right eye appears to the left, there is weakness of the internus. That is, if the line is seen at the right with the right eye and at the left with the left eye, there is weakness of the externus and too great convergence. The degree of a prism put before the naked eye, base out, that just brings the line into the flame gives the amount of the over-convergence, that MUSCULAR INSUFFICIENCY. 89 is, the measure of the weakness of the recti externi. In case of too great divergence the lines being seen at the left with the right eye, and at the right with the left eye, the measure is made with a prism, base in, similarly. Adduction of the eye is found by placing prisms of increasing strength, base out, before the naked eye; the strongest through which the eyes fuse the two images of a candle-flame at twenty feet, gives its measure. Abduction is found by prisms, base in, similarly. The Stevens nomenclature for these muscular deviations is convenient, and is as follows:Orthophoria, the visual lines tend to parallelism. Heterophoria, the visual lines do not tend to parallelism. ~ ( Esophoria, visual lines tend inward. I Exophoria, visual lines tend outward. HYI erphoria, tending of the visual line of either eye above its fellow. Hence exophoria signifies insufficiency of the internal recti, and esophoria of the external recti. Hyperexophoria would signify a tending of the visual lines upward and outward, and hyperesophoria, a tending of the lines upward and inward. To restore parallelism of the visual lines in esophoria, a prism with the base out is required; in exophoria, a prism with the base in. Very often there is an error of refraction to be corrected also, so that a convex lens in esophoria is combined with the prism, and in exophoria, a concave lens with the prism may also be necessary; and in either case there may be astigmatism, so that 90 REFRACTION AND ACCOMMODATION. sometimes one spectacle lens may be ground as a prism, a cylinder, and a spherical lens, to meet the required conditions. I do not find the daily gymnastic exercise of the external ocular muscles with prisms, as recommended by Stevens and others, to be of great benefit. Some patients say that these exercises make the eyes feel better; but I do not find that the weaker muscles are strengthened thereby. The apparent increase of strength in the internal recti is undoubtedly due to the knack that the patient gets of using his accommodation. Thus a patient of mine in a short time could overcome prisms of 80~, base out; but his exophoria of 1~ remained the same as in the beginning when his adduction was only 24~. Some patients do not acquire this knack readily, and then there is no apparent increase of strength in the internus. Prisms to assist the weaker muscles may often bridge over the unpleasant effects of muscular disarrangement until improvement takes place and the eyes work well without their aid. The asthenopia of a muscular insufficiency is often due to merely temporary lack of innervation in feeble or neurotic subjects. The apparent relative strength of the external ocular muscles in such persons, as measured by prisms, is extremely variable. Such a patient showed an exophoria of 16~, but after four days only 10~. After wearing prisms of 30, base in, for two weeks the exophoria measured 16~, then a week later 8~; a week later it became an esophoria, and later a slight exophoria. The prisms were discarded, a correction of a slight myopic astigmatism was made, the MUSCULAR INSUFFICIENCY. 91 Dyer method of exercise of the eyes practised, and the asthenopia and headaches steadily improved. In most people, an apparent want of muscular equilibrium is without significance; and the same is true of those showing a weak adduction or weak abduction. A medical friend shows an adduction of 10~, an abduction of 7~; but he has never had an asthenopic symptom. Another shows an esophoria of 1~, his adduction 7~, his abduction is 9~; and these measurements were carefully made and repeated. He should suffer from exophoria and suffer badly; he has never had anything more than a slight accommodative asthenopia from over-sight of one dioptric. A lawyer with adduction of 9~ and abduction of 8~ never had a symptom of eye ache, and rarely a headache in his life. Instances like these are not rare. The conditions as stated above, and the varying and unstable tension or weakness of these muscles are recognized by surgeons generally; but the situation calls for great conservatism in respect of operative interference. Tenotomy, or "button-holing," should be held in reserve for rare and exceptional cases. Some of the more distinguished ophthalmic surgeons, indeed, strongly oppose these operations. Thus Roosa says,1 in speaking of the prevailing treatment of muscular insufficiencies by many surgeons, " As to tenotomies nowhere in surgery has a more desolate field been left by operative procedure, than that made by oculists and neuralogists with mistaken zeal in the cutting of muscles of the eye." He says further, "I believe that none of these insufficiencies 1 Ophthalmic Review, vol. ix. p. 286. 92 REFRACTION AND ACCOMMODATION. lead of themselves to asthenopia," of which he believes refractive errors to be the cause, and that to the error of refraction is due the insufficient muscular action. "Those who have been examining the muscles so carefully have been considering effects, not causes." PRESBYOPIA. Far or old sight is a symptom of advancing years, and is due to senile loss of elasticity in the lens. Distant vision remains good, but no effort of the ciliary muscle is sufficient to render the lens convex enough to bring rays of light from near objects to a focus on the retina. Hence the necessity for convex glasses. It is not advisable to postpone the use of glasses as long as possible at the expense of discomfort and fatigue of the eye. The proper glasses for a presbyope are such as will enable him to read No. 1 at ten or twelve inches. It is convenient to have two pairs of spectacles, the stronger one for evening use. Rapidly increasing presbyopia is to be viewed with suspicion, as it is often a precursor of glaucoma. SECOND-SIGHT, popularly so called, occasionally comes to elderly people who, after using glasses for years, find themselves able to dispense with their aid, and yet read with tolerable comfort. Such persons have unusually small pupils, so that, practically speaking, only the central rays of light are admitted to the eye, and no focussing power is called for. MYOPIA SENILIS. 93 MIYOPIA SENILIS may also occur, so that not only is the absence of convex, but the substitution of concave, glasses an improvement to the vision. Such instances are due to commencing cataract, when, as sometimes happens, the lens has become more convex from swelling, but still retains its central transparency. This condition is often the explanation, also, of the "second-sight,"ordinary print, in such cases, being read more easily without the usual convex glasses. CHAPTER VI. THE CONJUNCTIVA. PASSIVE HYPERBEMIA OF THE CONJUNCTIVA. HYPERAM1IA of the conjunctiva is of very common occurrence, and is due to over-use or abuse of the eyes, or to optical defects, as in asthenopia. The appearance of the eye is very similar to that observed in mild conjunctivitis, but there is no discharge from the conjunctiva, and usually very little or no lachrymation, and the smarting, itching, and heaviness of the lids is markedly increased in the evening. Reading manuscript by strong artificial light, or by a too weak light, and the hazardous practice of reading habitually in the horse and steam cars, and that worst and most dangerous of habits for the eyes, that of reading in bed by artificial light, -often excite this congestion. This state of the conjunctiva may be a reflex symptom of a similar condition, or more, serious disease, of the internal structures of the eyes. The use of the eyes for reading increases the hyperamia and asthenopic symptoms, if such are present. Treatment. To cure this affection, it is of course necessary to remove its cause. Optical defects must be remedied by appropriate glasses. Injurious use of the eyes must be CONJUNCTIVITIS. 95 given up and overwork proscribed. As palliatives, the use of the eye douche, always with closed lids, is excellent, or bathing in tepid water, or vinegar and water, a few drops of tincture of hamamelis or tincture of opium or of hydrastis in a cup of water, or a grain or two of sulphate of zinc, or of acetate of lead, - any of these, adhering of course to the one which seems most grateful to the eye, may be used as a fomentation, either warm or cold, to the lids several times a day. If preferred by the patient, these lotions may be used to saturate a bit of lint or linen which may be laid over the lids for a quarter of an hour, three or four times a day. The solution need not enter the eye, but will, of course, occasion no pain of consequence in case this should happen. Sometimes fomentations of very hot water for five minutes, three or four times a day, suffice. CONJUNCTIVITIS. An inflammation of the conjunctiva is easy to diagnosticate, and yet a mistake is possible if one is not in the habit of observing accurately the difference in the appearance of a reddened eye in different kinds of inflammation. For instance, in the simplest conjunctivitis, in place of the usually invisible vessels of the conjunctiva, we have a network of bright red vessels plainly seen to be superficial and movable by the touch of the finger over the smooth surface of the sclerotica. On the other hand, in a severer, deeper-seated conjunctivitis, like the scrofulous, or lymphatic, and the granular, we have, in addition to this vascular network, the close parallel lines of immovable sub-conjunctival ves 96 THE CONJUNCTIVA. sels running towards the edge of the cornea, in a state of congestion. This condition gives a pinkish-red zone around the cornea, often more clearly defined in iritis and keratitis. In scleritis, or episcleritis, there is presented still another redness of a violet or purple tinge. It appears nearly always in rather large and tolerably well-circumscribed patches, and is sometimes mistaken by the general practitioner for phlyctenular conjunctivitis, although the bright red color and papular appearance of the latter, and the peculiar color of the deep-seated spots of the former, render the differential diagnosis easy in ordinary cases. Simple Conjunctivitis. Simple conjunctivitis differs in degree, rather than in form, from the acute catarrhal. It is generally the result of slight injury to the eye, contact of a foreign body, exposure of the eyes to dust, smoke, cold winds, or dampness, glare of light, impure air, or from some other local cause. The subjective symptoms are very trivial usually. There may be some itching and sensation of heat in the lids, or a feeling as if there were sand in the eye. We ought to determine by ocular inspection, whenever our patient complains of a sensation as if a foreign body were in the eye, or when a simple conjunctivitis does not yield readily to treatment, whether there may not be some foreign substance lodged beneath the upper lid. The immediate cure of a conjunctivitis after three weeks of ineffectual treatment, by the simple eversion of the upper lid and the removal of a bit of quartz, is mentioned in the chapter on Injuries of the Eye. CONJUNCTIVITIS. 97 Catarrhal Conjunctivitis. The objective symptoms in catarrhal conjunctivitis are more marked than in the simple form of the affection. The congestion of the superficial vessels of the conjunctiva is greater, and in elderly people chemosis may be present. The edges of the lids appear swollen, the palpebral conjunctiva is distended from serous infiltration, particularly at its reflected portion, its papilla are enlarged, and its surface presents a velvety appearance. There is a secretion of clouded mucus, alternating sometimes with a secretion muco-purulent in character. This discharge is often abundant, but rarely as profuse as in purulent conjunctivitis, and is more or less contagious. Probably the contagiousness is in direct ratio to the increased admixture of pus globules in the discharge. A healthy conjunctiva may be successfully inoculated with the secretion of an acute catarrh. The subjective symptoms are not very characteristic. There is the complaint of not seeing well at a distance, and the common symptom of a feeling at first of dryness, and as if sand or some foreign body were in the eye, and there is a heavy uncomfortable feeling about the lids which leads to a desire to rub them, and frequently a slight burning and smarting sensation. There is rarely severe pain,/ nor is the photophobia marked. The above subjective symptoms vanish, to a great extent, as a case becomes chronic. As to the treatment, it should be simple in acute cases. No doubt acute catarrh of the conjunctiva, under proper hygienic conditions, and under circumstances controlling the causes 7 98 THE CONJUNCTIVA. which have produced it, frequently disappears in the course of a week or two without any treatment whatever. In other cases, however, it may be sufficiently severe from the commencement to require treatment. Treatment. In the first or inflammatory stage the cold douche, or cold compresses, will afford great relief. No irritating collyria are permissible at this stage. Later, simple collyria, such as a solution of five to ten grains of borax, four grains of boracic acid, two grains of alum, or one grain of sulphate of zinc, one grain of nitrate of silver, each to the ounce of water, will often be found serviceable. A solution of bi-chloride of mercury 1:10000 may sometimes be useful also. If the affection prove very obstinate, and the discharge assume a puriform character, the case should be treated as a purulent conjunctivitis. A solution of nitrate of silver, of five grains to the ounce of water, may be used, but not as a collyrium. The lids, upper and lower, should be everted, and held in this position with the left hand; the patient should close the eye gently, this will bring the everted lids together and prevent contact with the cornea. The conjunctiva thus exposed is painted by means of a camel's hair pencil with this solution, which after a second or two is washed off with tepid water from another pencil. If the pain is afterwards severe, it will be relieved by bathing the eyes in cold water, by cold compresses, and frequently through simple contact of the eyes with the cool out-door air. The applications may be made daily or on every second CONJUNCTIVITIS. 99 day. The good results that often follow this use of the nitrate of silver are doubtless due to its germicidal properties. If active inflammatory symptoms are present, - that is, a very bright red, congested, and swollen conjunctiva when the sub-conjunctival vessels are visibly involved, and when the ciliary nervous system is sensitive, as shown by pain and photophobia,- irritating applications should not be made. In all cases where irritating collyria are used, it is advisable not to push their employment too continuously, but rather alternate them from time to time with the use of the cold compress. In chronic cases it is advisable to see that a collyrium which the patient takes home be not too strong. It is necessary, also, to remember that in a conjunctivitis occurring in two individuals of different nervous organization, where in each case it seems to be of the same nature and to require the same remedy, one may use a wash with great benefit which the other may be quite unable to bear. Whenever, therefore, there is doubt about the strength of the solution it is advisable to instruct the patient that if the pain after its use continues beyond a minute or two, it is too strong, and should be diluted with an equal quantity of water. It is safer, also, to direct that the collyrium be used not oftener than twice a day. It has often been my experience, when called in consultation with physicians, to find that in conjunctivitis, complicated and uncomplicated, collyria when used at all have been frequently too strong, applied too often, and to eyes already too sensitive and irritable. We should bear in mind the contagiousness of some 100 THE CONJUNCTIVA. catarrhs of the conjunctiva. The patient should be warned of this danger, so that he may not propagate the disease. Frequently the affection assumes an epidemic character, attacking whole families and neighborhoods. In the chronic form of this affection the results of topical application to the lids will not prove as satisfactory as in the acute. Improvements will be followed by relapses, and many cases will prove extremely tedious in treatment. If, however, the affection seems to be purely local and confined to the eyes, our prognosis will be more favorable than when it is merely a part of a catarrhal affection of the air passages generally or of the lachrymal duct. " Pink eye " is a form of epidemic catarrh seen mostly in young people, which is quite contagious and is usually most prevalent in the spring months. It derives its popular name from the fact that the ocular conjunctiva is usually deeply congested, giving the eyeball a noticeably pinkish-red hue. It is best treated by cold at the beginning and later by mild astringent washes. Owing to the ciliary irritation, pain, and photophobia irritating collyria are not well borne. A 1% solution of boracic acid I have found useful, also nitrate of silver 1:500 and bi-chloride of mercury 1: 25000. The disease, supposed to be caused by a small bacillus constantly found in the discharge, does not invade the cornea and the prognosis is favorable. HYGIENIC MEASURES. In conjunctivitis of all kinds, attention should be given to hygienic regulations. Very sensitive eyes should be protected against bright light during the day or PURULENT CONJUNCTIVITIS. 101 night by plain blue or smoke-colored glasses, which will afford also a measurable protection against wind and dust. Grayish-yellow glasses are lately recommended as grateful to the eyes if photophobia be present. The patient should use the eyes with moderation, especially by artificial light, and should carefully avoid all places where the air is necessarily impure, -such as crowded rooms, like the theatre, lecture-room, ball-room, or rooms where tobacco-smoke prevails. He should be counselled also to avail himself, as much as possible, of the beneficial influence of a pure out-door air, and should be advised that when necessary to use the eyes in reading,, writing, or fine work, preference should be given to the morning hours when the light is constantly growing better. PURULENT CONJUNCTIVITIS. Purulent conjunctivitis, which is to be regarded only as a severer and more dangerous form of the catarrhal, is distinguished from the latter by the character and greater abundance of the secretion, the greater swelling of the lids in consequence of the serous infiltration being also sub-conjunctival, the great injection of the sub-conjunctival vessels as well as the increased vascularity of the conjunctiva proper, the chemosis so frequently present, and by the increased size of the mucous papilla, often termed granulations. One of the most practical methods of determining at once whether you have a blenorrhcea or a simple catarrh to deal with, is, by the easy proceeding so long taught in the clinics of Arlt, of Vienna. The upper lid is to be everted, and if the 102 THE CONJUNCTIVA. conjunctiva is sufficiently transparent for us to see the lines of the meibomian glands running towards the edge of the tarsus, we have a catarrh; if the infiltration is so great as to hide these glands, we have no longer a catarrh but either a purulent, a granulated, a diphtheritic, or some graver form of ophthalmia. In purulent conjunctivitis the cornea is apt to become involved, and this form is generally more contagious, The Treatment, during the inflammatory stage in which there is often considerable fever, must be purely antiphlogistic. Icewater compresses should be perseveringly used, and these with the perfect quiet of the patient, and the administration of aconite, suffice to control measurably the acute symptoms. I have never resorted to the use of leeches, and I have often seen them used in these cases when I thought them unnecessary. If but one eye is attacked, the other should be bandaged as a precautionary measure, and in all cases of purulent ophthalmia the attendants should be warned that the greatest cleanliness and attention to the contagious character of the secretion is necessary for their own safety. After the inflammatory symptoms are subdued, as shown by the diminished swelling of the lids and the pale-red and relaxed condition of the conjunctiva, and the watery discharge become thicker and purulent, anti-septic applications are indicated. If the cornea is involved, care must be taken. that a caustic application does not come in contact with it, by painting it on the everted lids and immediately washing it off as pre INFANTILE OPHTHALMIA. 103 viously directed. See Treatment of Gonorrhceal and Infantile Ophthalmia. Egyptian, or military, ophthalmia is a variety of purulent conjunctivitis often complicated by a follicular granulation. It was first recognized and named after an unprecedentedly severe epidemic originating in the troops of the English and French armies stationed in Egypt. It spread so fearfully that after the Napoleonic wars, England alone had upward of five thousand blind invalided soldiers to care for. It is doubtful whether this form of the disease is more contagious than any other. Very likely any form of the affection getting a foothold among masses of people crowded together — as in armies, alnshouses, and charitable institutions - would spread rapidly. Uncleanliness and bad ventilation are attractive conditions for this disease. The contagion of a purulent ophthalmia, as is well known, may engender a very light or a very severe form of the affection, -a mere catarrh or a diphtheritis. In the beginning the disease is hardly contagious, but becomes so as it progresses, and the discharge increases in quantity and consistency. The form of the disease produced by contagion seems to depend on local or atmospheric conditions as well as upon the constitution or age of the person infected. See Treatment of Follicular and Granular Ophthalmia. INFANTILE OPHTHALMIA. Conjunctivitis in the New-born. Ophthalmia neonatorum is a purulent conjunctivitis which comes on a day or two after birth. Excep 104 THE CONJUNCTIVA. tionally it may make its appearance not until the sixth or seventh day after birth. It begins by a redness and swelling of the lids and a slight watery discharge which sometimes increases with great rapidity a few hours later. Its cause is generally to be sought in a gonorrhoeal or leucorrhceal discharge of the mother. In mild cases where the discharge is whitish, not very abundant, and chiefly mucous in character, the free use of cold compresses, a careful and frequent removal of the secretion with a bit of absorbent cotton may suffice to carry the ease through to a speedy and successful termination. Such are mild cases. In other instances the affection is severe, and requires prompt and energetic local treatment in order to insure favorable results. The responsibility of the physician in a severe case of ophthalmia neonatorum is very great. Intelligent treatment is surprisingly effective, but negligent or unskilful treatment is often deplorable. Our asylums for the blind afford many mournful examples of the results of neglect or bad treatment in this affection. TREATMENT OF SEVERE CASES. If the disease increases in severity in spite of our treatment, we ought never to neglect to determine by careful inspection whether the cornea be intact or not, because upon this condition depends the treatment and the nature of our prognosis. It is not a very difficult matter to obtain a view of the cornea even when the lids are much swollen. The child is to be held by the nurse, its head resting between the knees of the surgeon, and in this position there is generally little difficulty in TREATMENT OF SEVERE CASES. 105 forcing the lids apart. If the fingers alone are insufficient in consequence of the swollen condition of the conjunctiva, an elevator may be used. It is remarkable how neglectful many physicians are of this simple procedure, but in no other way can a case be treated intelligently. After the inflammatory symptoms have been reduced by the use of cold compresses, and the discharge has become purulent, I use a collyrium of nitrate of silver, one grain to the ounce of water. It is quite mild, and I believe generally very effective. It is particularly indicated when the discharge is copious and wholly purulent. This should be dropped into the eye, after it has been carefully cleansed from the discharge, twice a day. A change of collyria often hastens the cure; and one of the best substitutes for the above is boracic acid, ten grains to the ounce of water. It may be used five or six times a day, or one may use a mild wash of bi-chloride of mercury 1:20000. In a few days, if the profuse discharge still continues, and especially if the increased haze upon the surface of the cornea indicates a complication in this direction, a solution of five grains of the nitrate of silver to the ounce should be painted with a brush upon the everted lids and immediately washed off with tepid water or neutralized by the application of a solution of common salt and water. No evil consequences whatever can result from this proceeding, and not unfrequently the beneficial results of it are seen after a single application. It need not be often repeated. Cold compresses may be employed to lessen the irritation immediately afterwards, and I prefer as internal remedies after aco 106 THE CONJUNCTIVA. nite in the commencement, mercury when the discharge is profuse, and the alternation of arsenicum with this remedy if the cornea is ulcerated. It is advisable in these cases, so long as the discharge is profuse, to direct that the discharge be carefully removed from the eye every half hour with absorbent cotton, by day, and every hour by night. I will give the outlines of a case which occurred twenty years ago in illustration of this treatment. Mrs. G., of Boston, brought to me her babe, three weeks old. It had been suffering from purulent conjunctivitis since two or three days from its birth, and, up to the date of her visit, had been steadily growing worse. The physician in attendance had not attempted an examination of the cornea, but had advised her to keep the eyes as free from the discharge as possible, to apply cloths wet in cold water, and had administered small powders internally. The lids were somewhat reddened and swollen in appearance, and considerably puffed up, from the quantity of pus beneath them. After the removal of the accumulated pus, which was accomplished by repeatedly separating the edges of the lids, giving it exit, and wiping it gently away with a soft sponge wet in tepid water, I was able, by means of an elevator, to open the lids sufficiently to determine the condition of the cornea, and make a prognosis as well as diagnosis. The cornea of the right eye was found hazy, and slightly opaque at its upper and inner edge. In the left eye, the corneal opacity was greater; and directly over the pupil was an ulcer which had already broken through, and occasioned, as I afterwards found, a deposit of matter upon the anterior surface of the capsule of the lens, and a slight adhesion of the free edge of the iris. The mother was informed that the mischief done to the left eye was irreparable; that perfect restoration of sight was impossible; that the disease would probably progress no further, and that vision, to a limited extent, would be preserved to this TREATMENT OF SEVERE CASES. 107 eye. As to the right eye, there was no question as to its perfect restoration. The lids were reversed and painted with a solution of nitrate of silver, ten grains to the ounce of water, which was allowed to remain only a second or two, and immediately washed away with tepid water. The nitrate of silver was used in an unusually strong solution, because it seemed necessary to check at once, if possible, further progress of the disease. I have noticed that when a case is severe, the lids considerably thickened, and the mucous papillae very much swollen and prominent, it will bear, with good results and without marked reaction, a much stronger solution of nitrate of silver than it would be prudent to apply in a milder case. In this instance, the mother informed me, on her second visit, that the night after the application of the caustic was the best which the child had passed since its birth. There had been no reaction, and consequently no application of cold to the lids had been necessary. Under the circumstances, I concluded to touch the lids a second time with the same solution. This was done on the second day; and again the child had a remarkably comfortable night. On the fifth day, the discharge, which had been very profuse, was considerably lessened in quantity. The mother herself could see a decided improvement, and began to have great confidence in the treatment. I now diluted the solution with an equal part of water, making it five grains to the ounce; and after a week, it was reduced still more, making it about two grains to the ounce. I had taken the precaution, also, of dropping into the left eye a solution of atropine, two grains to the ounce, in order to draw away the edge of the iris as much as possible from the corneal opening. The application of the solution above described was made but six times, at intervals of forty-eight hours, when, the discharge having almost entirely ceased, I gave the mother simply a solution of sulphate of zinc, one grain to the ounce of water, to be dropped daily into each eye; and in two weeks from this time the child was well enough to require no further treatment. 108 THE CONJUNCTIVA. THE PREVENTION OF INFANTILE OPHTHALMIA. At the Lying-in Hospital at Leipsic the following prophylactic treatment is adopted. The eyes of the infant are immediately washed out with water, a drop of a two per cent solution of nitrate of silver is instilled, and the eyes are covered for twenty-four hours with cool compresses moistened in a two per cent solution of salicylic acid. These measures were first adopted for the infants of diseased mothers only, but subsequently extended to all others. The result was, that for six months, in two hundred infants so treated, not one case of ophthalmia occurred. In one case where the application of the nitrate of silver had been accidentally neglected, a slight case of conjunctivitis appeared. A simpler treatment is employed at Halle; namely, for nine months the eyes of the infants were washed out, as soon as the head was born, with a one per cent solution of carbolic acid. This treatment reduced the percentage of ophthalmia from 12.5 per cent to 3.6 per cent, and the disease when it did appear assumed a milder form. It would seem, in view of the above facts, that a grave responsibility for the condition of the eyes of the new-born rests upon the obstetrician. I recall last year an otherwise perfectly healthy infant, sent to me by the family physician for treatment; the child was four weeks old, and both corner wholly destroyed from purulent inflammation. Of course the child was totally blind, and was to go through life totally blind. Such cases would be almost impossibre if a careful prophylactic treatment were generally observed. It is entirely feasible for a physician to carry out the treatment. Undoubtedly nitrate of silver is the most available germicide we have for the eye. A solution in water of 1: 100 - that is, four to five grains to the ounce - destroys vitality in about twelve seconds. Carbolic acid is too irritating for the eye, in any solution strong enough to be effectual, and the same may be said of hi-chloride of mercury, 1: 1000 being required to destroy vi CASE OF GONORRHIEAL OPHTHALMIA. 109 tality in forty-five seconds. To be effective the fluid should act quickly because it becomes diluted almost at once by the secretions of the conjunctiva.. A 1 % solution of nitrate of silver is therefore the preferable germicide to be used as a prophylaxis; and the next best, but far less certain, and more irritating, are carbolic acid I: 100 and bi-chloride of mercury 1: 5000. Boracic acid prevents the development of germs but does not destroy them. A -o% nitrate of silver solution will produce a similar effect. GONORRH(EAL CONJUNCTIVITIS. Gonorrhoeal conjunctivitis, so called, is a variety of this affection associated with a similar discharge from the urethra, due to sympathy or extension of the virus over the system, or, as more frequently happens, to direct contact of a urethral discharge with the eye. In the former case, the attack occurs simultaneously in both eyes; in the latter, it commences in one eye first, generally the right, and in its severe form is one of the most rapid and destructive diseases to which the eye is subject. In its mild form the disease resembles a light purulent ophthalmia, and requires similar treatment. In the contagious form, the inflammation is sometimes exceedingly violent. I cannot describe the nature and treatment of this disease better than by giving the main details of a case of a severe type under my care many years ago. CASE OF GONORRHCEAL OPHTHALMIA. G. L., a young man of seventeen, was brought me by his father, Oct. 10, 1868, to be treated for an inflammation of the eyes. The right eye was closed, the upper lid so largely swollen that, at first glance, I thought of abscess. On turning my atten 110 THE CONJUNCTIVA. tion for a moment to the other eye, the lids of which were but little affected externally, I noticed considerable injection of the vessels of the conjunctiva on either side of the cornea. The affection of the right eye had been noticed first two days previously; but the great swelling had not come on until this morning. The pain was not very severe; the patient, pale and anxious-looking. The lower lid was but slightly distended, and by drawing it downward and away from the upper one which overlapped it, I could see a marked chemosis of the conjunctiva of the globe. There was no doubt about the diagnosis of the case. As the father seemed nervous and apprehensive, however, I concluded to say nothing about its peculiar nature for the moment, telling him simply that the affection was severe, that the left eyelids, on the next day, would probably be very much in the condition presented by those of the right eye to-day; that the boy was not well enough to be out, and that he must be treated in bed. Ice-water compresses to be applied to right eye constantly, and to the left whenever the cold could be borne or felt grateful. Aconite to be taken every hour. The next morning the external appearance of both eves was about the same, the upper lids of both being enormously distended. The right was less sore to the touch, and I was enabled to determine the state of the globe more definitely. The cornea was still intact, but considerably lessened in circumference through the overlapping of the conjunctiva, the chemosis being very great. The conjunctiva bulbi was red and puffed, looking "like a piece of raw meat." Pulse, one hundred and twenty. Ice-water compresses to be continued night and day. Aconite internally. I now ascertained that the patient had contracted a gonorrhcea three weeks previously. The discharge from the urethra is still rather profuse. Oct. 12. Externally the swelling of the lids is somewhat lessened, the appearance of the eyes the same. The discharge is rather thin and flocculent, not such as could be desired. The pain is not severe; pulse about the same; prognosis doubtful. The same treatment to be continued. The sanious discharge CASE OF GONORRHCEAL OPHTHALMIA. 111 to be wiped out from beneath the upper lid with a camel's-hair pencil moistened in warm water, and the edges of the lids to be tenderly cleansed with a soft sponge and tepid water, Oct. 13. Swelling of the lids much lessened externally. In flammation is still too acute to admit of caustic application. Appearance of the globe the same, the chemosis being considerable. Discharge still watery and slight. Used twice a day a weak solution of carbolic acid in cleansing the inner surface of upper lid. Attendants getting weary and worn in changing the ice-water compresses night and day, I had two little ice-bags constructed and connected by a bridge, like diminutive saddlebags, to be saddled across the nose, the little bags filled with small bits of ice to rest one over each eye. The upper lid was found still too tender to bear their weight, but a day later they could be borne, and were afterwards used constantly, thereby saving the nurses much labor. Aconite and mercury internally. The discharge during the next few days became more copious and pus-like, and the external lids became gradually less swollen and red. Oct. 15. Appearance of conjunctiva nearly the same; cornea not fully transparent, that of the right eye quite hazy at its upper third. Raised the upper lids and painted them with nitrate of silver, five grains to the ounce, immediately washing it off with tepid water. Oct. 16. Treatment continued. Oct. 17. Considerable pain in the left knee, which I found slightly swollen, and very sensitive to touch. A water compress was applied; pulse, which had fallen to one hundred, now rose again to one hundred and twelve. Aconite and macrotin internally. Oct. 18. Left knee-joint largely swollen, measuring, with the leg extended, fourteen inches at its largest circumference; sensitive to pressure, and immovable; but less painful than yesterday. Right knee painful, and beginning to swell. Discharge from urethra continues. Eyes much the same in appearance. Cornea of right eye the worse of the two. Prognosis, which 112 THE CONJUNCTIVA. had seemed for a few days more favorable, now again doubtful, in consequence of this new inflammation of the knee-joints, which bids fair to reduce the vitality of the patient as it has already his courage, and renders the question as to the power of the cornea to maintain the integrity of its tissues a doubtful one. Treatment continued. Oct. 22. Fever lessened, more appetite, knees less painful, but largely swollen, and the right one immovable. Eyes no better; discharge quite copious. Treatment the same. Oct. 23. Discovered, this morning, what I had been fearing from the first, - namely, ulceration of the cornea. The chemosis having in a measure subsided, the conjunctiva bulbi had receded from the edge of the cornea, which it had previously overlapped, and so uncovered in the right eye a crescent formed ulcer extending nearly around the upper half of its circumference. It was deep, its edges sharp and clean, so that it was necessary to look closely in a favorable light to see its whole extent. An ulcer on the left cornea in nearly the same relative position, not so great in extent, but still ugly and dangerous looking, was discovered also. Both ulcers looked, I thought, as though they were growing larger, therefore without some change of treatment the right eye would certainly be lost, and perhaps the left one too. I therefore made an immediate change in treatment. His pulse was one hundred, the tongue was nearly clean, and he had expressed a strong desire for solid food. I determined, if possible in the present state of his digestive organs, to gratify his wish to the fullest extent. A rare beefsteak was prepared for him at once, and he was to be fed similarly three times a day. Beef-tea was also to be in readiness, so that if he tired of steak it could be substituted for it. He was to have at each meal all the rare beef he desired. I further substituted for the solution of nitrate of silver, which I had been using, one of fifteen grains to the ounce, applying it thoroughly to the reflected portion of the upper and lower lids, and immediately washing it away with tepid water. It caused no pain whatever. Mercury and macrotin were given internally. CASE OF GONORRH(EAL OPHTHALMIA. 113 Oct. 24. Ulcers look no better; knees improving slowly, and can be drawn up or moved slightly without great pain, but are still largely swollen. Patient eats freely of the steak and digests it without trouble; slept better than usual through the night. The discharge from the eyes is rather less; continued treatment; but before the cauterization I dropped a solution of atropine into each eye to keep the iris rigid, and as much as possible away from danger in case of rupture of the cornea from the ulceration. After the cauterization the eyes are bandaged sufficiently tightly to prevent movement of the lids. I find the eyes bear this cauterization, repeated every twenty-four hours, well, and it has already lessened the discharge. Oct. 26. Ulceration appears slightly improved, especially il the left eye, where the edges of the ulcer are slightly tinged with yellow, and at the bottom a gelatinous look, as though the reparative process were commencing. Similar indications, but less marked, are also to be seen in the more important ulcer of the right cornea. Patient complains of shortness of breath, which I find is probably occasioned by overtaxing the digestive organs, so I restrict the diet somewhat in quantity, and give nux vomica and bryonia for twenty-four hours. Other treatment continued. Oct. 28. Shortness of breath gone. The eyes are decidedly better. The ulcers are slowly filling up. Discharge from the eyes less. The cauterization now causes quite severe pain, so that ice compresses have to be resorted to afterwards, for a half hour before bandaging. Internally mercury and macrotin. Oct. 30. Eyes improving; knees improving also, but slowly. The present solution of nitrate of silver being now too strong, I reduce it one half, making about seven and a half grains to the ounce, which is borne well. Discharge from the eyes much less; from the urethra, also, somewhat less. Patient's appetite good, and he is allowed to indulge it in nourishing food to the fullest extent. Nov. 6. Improvement in all respects; he manages to walk about the room moderately. Ulcer in the left cornea reduced 8 114 THE CONJUNCTIVA. to a mere trace, that of the right surely but slowly filling up. He can read coarse print. Nov. 12. Acuteness of vision is nearly perfect, as the opacity, left on the cornea from the ulceration and the reparative process, does not encroach at all on the pupil. I may mention here that, some three months afterwards, this patient came again under treatment for rheumatic iritis,- a disease of the eye, which often follows gonorrhceal rheumatism. The affection of iris in this instance was only of three weeks' duration. Conjunctivitis diphtheritica is very rarely seen in this country or in England. It is occasionally epidemic in Berlin. It resembles the preceding in many respects, but is usually more severe and dangerous. The discharge is at first, yellow, thin, and flocculent, the swollen lids rigid from deep-seated fibrinous effusion, the pain and heat very great. In a few days the discharge assumes a purulent character, the lids become less rigid, there may be fibrinous exudation from the conjunctiva, the cornea is very apt to grow hazy and ulceration or sloughing ensues. The treatment indicated is that for purulent ophthalmia, except that much greater caution is necessary in the use of caustic or irritating applications. Membranous or croupous ophthalmia resembles the diphtheritic, but is less severe, and there is less rigidity of the lids. It is not often met with here. I have had only two cases in twenty years. The treatment is similar to that for purulent ophthalmia. CONJUNCTIVITIS FOLLICULOSA. 115 CONJUNCTIVITIS FOLLICULOSA is seen first in the temporal portion of the conjunctiva of the lower lid in a number of slight, semi-transparent vesicles. These are swollen lymph follicles, and when numerous may extend to the upper lid, and cover the entire palpebral conjunctiva, but more thickly the reflected portions. It is often found in connection with granular or trachomatous affections, of which it is a variety, or a milder phase, and like those is due often to unfavorable hygienic surroundings. By itself, unmixed with trachoma, follicular conjunctivitis does not result in cicatricial or other structural change in the conjunctiva or pannus. Uncomplicated cases are nearly always mild, and sometimes so mild as to occasion no inconvenience even. when the swollen follicles are quite numerous. But this condition renders the mucous membrane of the lids more susceptible to inflammations of all kinds. Usually the subjective symptoms are those of a hyperamia; after use of the eyes there is burning, congestion, a feeling as of sand between the lids, and there may be a slight discharge which is contagious. Treatment. The simple astringents mentioned for acute catarrhal conjunctivitis will often prove efficacious; but, on the whole, I have found a collyrium of boracic acid, of from six to eight grains to the ounce of water, more generally useful than any other. Strong astringents or caustics should never be used. The affection is often obstinate, recurring again and again; and when this occurs there 116 THE CONJUNCTIVA. will generally be found some constitutional dyscrasia. See Treatment of Scrofulous Ophthalmia. In a case of an adult that I have recently been treating, irritation, lachrymation, and photophobia were the troublesome symptoms. Perfect rest in a dimly lighted room, and the free use of a six grain solution of boracic acid, were the measures that proved most grateful and beneficial. The attack lasted four weeks. He informed me that he was always apprehensive of a recurrence of the disease, as he had suffered from similar attacks, at intervals, for a dozen years. Sometimes they had been slighter, and sometimes more severe than this. ACUTE CONJUNCTIVITIS GRANULOSA (TRACHOMATOSA) is characterized by pain in the eye, photophobia from ciliary irritation, and particularly by the sensation as of a foreign body beneath the lids. If the latter be everted there will be noticed in addition to the swollen papillae, and intermingled with them, little gray points which are true or follicular granulations. After a week or more, the conjunctiva becomes more swollen, the discharge abundant and purulent, and at this stage of the disease it is difficult to distinguish the affection from a conjunctivitis purulentia. This purulent stage continues for some weeks, and may be treated as a conjunctivitis purulentia, exercising great care in regard to the use of irritants. So long as photophobia and lachrymation are marked, no irritating collyria can be used safely. Later, with the exercise of this caution, the affection may be treated like the chronic form mentioned on the next page. The cause of this affection is, CHRONIC CONJUNCTIVITIS GRANULOSA. 117 generally, defective hygienic conditions and contagion. It spreads rapidly, like the military ophthahllia, among masses of people. Either from neglect of all treatment, or from improper or imperfect treatment, or want of persistence on the part of the patient, the disease is very apt to become chronic. The secretion diminishes little by little, the general inflammatory state of the conjunctiva disappears, and the disease concentrates itself beneath the upper lid, and we have a CHRONIC CONJUNCTIVITIS GRANULOSA, and generally this is soon supplemented by an affection of the cornea, called pannus. Trachomatous pannus is a vascular development within the epithelial layer of the cornea. There is sometimes an extension of the granulations from the upper lid to the ocular conjunctiva, and thence to the cornea, but a pannus may be caused by friction and pressure upon the cornea of the roughened surface of the palpebral conjunctiva, and usually therefore, when we see it, we know without further examination that we have a granulation of the lid. The granulations, which are often of a mixed form, papillary and follicular, are on the inner surface of the upper lid, mostly upon the reflected portion, and the pannus, of course, is generally found upon the corresponding upper half of the cornea. When later, it has extended downward and encroached somewhat upon the pupil, so that vision is impaired, the patient becomes alarmed, and seeks the advice of the physician. The indication in a case of this kind is invariably to cure the granulated 118 THE CONJUNCTIVA. lid. This being accomplished, the pannus disappears of itself. A further unfortunate condition, whether pannus be present or not, is found in the structural changes in the lids due to old granular affection. These are dryness, shrivelling, and cicatricial contractions of the conjunctiva. This in turn may lead to displacement of the cilia, trichiasis, districhiasis, entropiFIG. 22. on, or xerosis. Fig. 22, from Nettleship, shows a granular lid and the beginning of structural change. TREATMENT OF GRANULAR OPHTHALMIA. The treatment of this class of cases is sometimes difficult and discouraging, owing to frequent relapses. If, as is frequently the case, the patient has suffered for many months or years, has been previously treated unsuccessfully, is gloomy and despondent in anticipation of coming blindness, he should be assured that his case is not hopeless; and that, with the proper amount of perseverance on his part, a permanent relief, with a more or less complete restoration of vision, is almost certain. A pannus - something growing gradually over the sight of the eye, and threatening eventually to shut out all vision - is usually a disease of fearful omen to the patient. He comes to the surgeon, also, with fear and trembling, from the idea that the growth upon the cornea must be cut off. No doubt this view is sometimes imparted by the physician who confounds the TREATMENT OF GRANULAR OPHTHALMIA. 119 growth with that of pterygium. The patient then, in the first place, should be rendered as cheerful and hopeful as possible. Hygienic regulations, such as previously mentioned, should be strictly enforced, and the general health, which in these cases is apt to be deficient, must be restored. As a local means of curing the granulated lid, I employ a smooth crystal of alum, a crystal of sulphate of copper, and occasionally a crayon composed of one part nitrate of silver to two parts nitrate of potash. Pure nitrate of silver in substance I never use. A smooth crystal of sulphate of copper is, perhaps, most serviceable when the eye is in condition to be benefited by irritating applications. The upper lid being reversed, it is drawn lightly and quickly across that portion of the lid seen to be thickened and granulated, and those portions of the conjunctiva not involved are carefully avoided. Considerable pain will ensue; and if the patient is very sensitive, it is advisable to apply tepid water or weak salt and water to the conjunctiva the instant after the touch with the caustic. Otherwise, the patient may, after the lapse of a few minutes, if the pain does not cease of itself, bathe the eyes in cold water. Immediately after this application the eye will present a reddened and injected appearance, and should on no account be used until this injection disappears, which will be perhaps in an hour or more. There will also be a feeling of irritation in and about the eye, and until this artificial irritation has fully disappeared, no second application of the crayon should be made. Whether, therefore, the process is to be repeated once in forty 120 THE CONJUNCTIVA. eight, or seventy-two, hours, or not oftener than once a week, must depend entirely upon the reaction caused by it. Meantime cold or hot water may be used freely; vaseline, if the lids adhere together in the morning, and the administration of constitutional remedies, when necessary, continued. In sub-acute cases, where there is considerable secretion, the application of a solution of nitrate of silver in water, of the strength of five or ten grains to the ounce, will be useful. It should be painted upon the reversed upper lid, and after fifteen or twenty seconds, neutralized by weak salt and water, from a second brush. In many cases, and especially in such as have been treated injudiciously or too heroically, mild applications will prove more beneficial. Such, for instance, are the aqua chlori, diluted with water onehalf or more, a solution of one to three grains of either nitrate of silver, sulphate of copper, aluminate of copper, alum, sulphate of zinc, to an ounce of water. In some cases I have used an unguent of one grain of sulphate of copper, or aluminate of copper, to the drachm of vaseline or lanoline. A mild unguent of the same may be made by adding three grains of tannin to the drachm. It is prudent to begin with mild applications if there is much ciliary irritation, and in many cases it will *be necessary to feel our way along by frequent change of remedy. Sometimes the eye will bear no irritant whatever. Pressure is frequently a potent auxiliary in these cases. It can be accomplished by placing a dry compress of absorbent cotton over the gently closed lids, so arranged that it shall be thickest at the angles TREATMENT OF GRANULAR OPHTHALMIA. 121 and diminished gradually towards the meridian, in order that the pressure exerted may be as uniform as possible over the granulated surface. An elastic band —flannel makes a good one- is then passed around the head, to hold the compress firmly in its place, and may be drawn as tightly over the eye as can be conveniently borne. This bandage is to be worn night and day, and the compress is to be readjusted upon the eye as often as it becomes displaced. I will relate a case or two in illustration of this mode of treatment. Miss B., aged twenty-four, visited me first in April, 1865. She complained of irritation and weakness in the left eye, and had recently become much alarmed at the discovery that she could scarcely see to read with it. I found a fully developed pannus extending nearly to the centre of the pupil, well supplied with vessels extending downward across the limbus cornea on to its substance. The prognosis, as far as improvement of vision in this eye was concerned, was favorable; complete restoration, a sharp, distinct vision like that of the normal eye is very often impossible. The faintest remnant of haziness of the cornea will occasion indistinctness sufficient to annoy the patient. When no cloudiness remains, and the cornea regains its transparency, if there is the least irregularity of surface, minute depressions or flattened facets, the rays of light will be abnormally bent in passing through the cornea, and the image upon the retina will be deformed and more or less indistinct. If, therefore, a doubt exists as to a complete restoration of the cornea it is unwise to promise a perfect recovery of vision. The case of this patient was a very old one. In her early youth she remembered an affection of her right eye, and the sight had never been as clear as that of the left up to the present attack. On examining the cornea of the right eye by lateral illumination, little irregular 122 THE CONJUNCTIVA. flattened facets were distinctly seen, which accounted for the lack of sharpness of vision. The lid of the left eye was reversed, and the cause of the growth upon the cornea was found il the granulated state of the conjunctiva. The diseased surface was lightly touched with a crystal of sulphate of copper, very cautiously at first, until the eye became somewhat accustomed to the process. Severe pain followed the operation for the first two or three times, but this was effectually controlled by bathing the eye in cold water and exposure to the open air. This eye had suffered from an acute attack of inflammation, as she informed me, more than a year before, but had apparently fully recovered after a few weeks. For a while it continued strong, but gradually grew more and more irritable, until within a few months she had scarcely been able to use it at all. She was under my care nearly five months, and completely recovered. This process of cauterization was repeated on an average about once in three or four days. Mercury was the remedy principally administered, although she had other remedies for disturbances in her general health during this period. Towards the end of the treatment my attention was called to the benefit of bandaging the eye in similar cases, and she employed this means also with the effect, I think, of hastening the cure. On visiting me nearly two years later, while with the right eye she was unable to read No. 1 type, with the left eye, the one which had been under treatment so long for'the pannus, she could read it with ease. Miss W. came to me first in May, 1867. She also, like the other, was suffering from pannus upon the left eye, and from the same cause. Like the other, also, she had suffered years previously from a probably similar affection in the other eye, The right eye she affirmed had been cured by a doctor in Boston, who had cut the cornea across its upper portion superficially, and had also made longitudinal incisions upon the inner surface of the upper lid. These incisions, she said, were painful, but always afforded her relief, and eventually cured her eye. She wished me to treat her left eye now in a similar manner. I TREATMENT OF GRANULAR OPHTHALMIA. 123 declined her method, and touched the granulated lid lightly with a bit of sulphate of copper, but it would not do. After a week I gave up the attempt to touch the granulations at all. The eye was rather the worse for the treatment. The ciliary system of nerves was involved to such a degree that the irritation caused profuse lachrymation and severe pain and photophobia. I therefore gave up temporarily the use of irritants of all kinds. Water was used several times a day, and a compress and bandage, as previously described, was applied, to be worn always at night, and, when convenient, during the day. After two or three weeks there was much less congestion, and the pannus had so far disappeared that the patient could read large print with tolerable fluency. I now began brushing the granulations beneath the lid with a weak solution of sulphate of zinc, which I found could be borne every two or three days. The bandage was continued with great benefit, and during the first part of the treatment, while the eye was irritable, spigelia, and later, mercury were administered internally. After two months' treatment no trace of the pannus was left, and vision was the same in either eye. Aqua chlori is recommended for obstinate pannus from granulated lids, and two to four parts of olive oil to one of oil of turpentine also. Inoculation of the eye with pus to create an acute purulent inflammation has been more or less successful in desperate cases in clearing up the cornea and restoring vision, and the same may be said of jequirity, but both these measures are heroic and not without danger. Peritomy, an operation in which the conjunctiva with its sub-tissues is excised with forceps and scissors, around the edge of the cornea, I have seen Mr. Bowman, of London, perform with good results. Favorable results, it is said, have also followed the operations of lengthening the palpebral fis 124 THE CONJUNCTIVA. sure, so as to remove the pressure of the upper lid upon the cornea. The more experience one has in granular or trachomatous conditions of the conjunctiva, the more one is inclined to prefer the milder to the so-called heroic treatment. Caustics and strong astringents are sometimes necessary, but their use should not be prolonged, and they may often be dispensed with to the advantage even of eyes that appear to tolerate them fairly. Thus, I find myself of late years substituting a crayon of alum in cases where formerly I should have used a crayon of sulphate of copper, and I often use a three grain solution of nitrate of silver. Naturally, much depends upon the fact as to whether ciliary irritation exists to any great extent. If it does, caustic or astringent applications are not borne well, and may do harm rather than good. Pain, photophobia, and lachrymation indicate ciliary irritation, and when considerable, contra-indicate astringents, apart from other considerations. In some of these cases one should carefully regard the condition of the iris. Atropine will sometimes be useful. Recently, as an intercurrent application, I have found boracic acid, four to six grains to the ounce of water, serviceable. In acute or sub-acute cases the boracic acid, being a disinfectant as well as a very mild astringent, may be used freely several times a day. When used in a four grain solution in cases of even marked ciliary irritation, it is usually borne well and is often decidedly beneficial. DIAGNOSIS. 125 SCROFULOUS CONJUNCTIVITIS OR SCROFULOUS OPHTHALMIA I place in this chapter, inasmuch as its primary seat is usually the conjunctiva; the cornea, iris, and sclerotica becoming later involved. DIAGNOSIS. It is hardly necessary to dwell on the diagnosis. The mere circumstance that ciliary irritation and photophobia so affect the orbicularis that its spasmodic closure nearly renders it impossible to see the eye at all, is of itself an almost unerring indication of the nature of the disease. It is necessary, however, to see the eyeball, in order to determine its precise condition, and form a correct prognosis. A few whiffs of chloroform or ether will sometimes quickly relax the orbicularis; but I prefer a resort to the lid-elevators, to be used as mentioned in ophthalmia neonatorum. Separating the lids we shall find the palpebral conjunctiva red, swollen, and velvety looking, the ocular conjunctiva injected, the pinkish zone around the periphery of the cornea well marked, the cornea probably dull, opaque, or ulcerated, and the iris perhaps contracted. There is sometimes a good deal of ciliary neuralgia present, and the dread of light may be so intense that the child cannot be induced to turn its face towards the most moderate light, even with its eyes tightly closed. Fortunately the disease is not always so severe as this, and the photophobia much less intense. In these cases, by means of coaxing, and some little artifice to excite their curiosity, we may, through the exercise of 126 THE CONJUNCTIVA. considerable patience, arrive, with most children, at a hasty view of the cornea sufficient for our purpose. Cocaine, if the case is docile enough to permit its use, will make the examination easier. Often the cornea will be found nearly transparent, and the disease confined to the conjunctiva and edges of the lids. Generally, however, even if the cornea appears unaffected, the ocular as well as palpebral conjunctiva is involved, and the inflammation is so deep seated as to reach the vessels beneath the conjunctiva, as shown by the pinkish zone around the edge of the cornea. The irritation of the ciliary plexus of nerves is marked, the eye is exceedingly sensitive to all external influences, there is copious lachrymation, and any irritation is followed by violent reaction. In some chronic cases these symptoms are measurably lessened in severity, but after all a leading characteristic of these cases is the ciliary irritation, and the consequent extreme sensitiveness of the eye. I dwell on this point because of its importance in the treatment. TREATMENT OF SCROFULOUS OPHTHALMIA. The treatment of these cases must be largely constitutional. The disease of the eye is but one of the manifestations of a disorder that pervades the entire system, and topical means can at best be only palliative. Soothing applications, however, like tepid water, milk and water, quite warm or hot fomentations of water, or warm water medicated with belladonna or chamomile or poppy leaves, atropine, or cocaine will frequently quiet a ciliary neuralgia or great restlessness, when TREATMENT OF SCROFULOUS OPHTHALMIA. 127 simple internal remedies alone do not suffice. There are, moreover, some phases of this disease, such for instance as when its chief seat appears to be the edges of the lids, where a mild mercurial ointment, rubbed gently between the cilia, - if necessary while the child is asleep, - will produce sometimes marvellously favorable results. It should be continued a long time nevertheless, if we hope for permanent benefit, and mercury may be given internally at the same time. This is not the place, nor is it necessary, for me to remark at length on the nature or pathology of what is called scrofula and its appropriate treatment in general. In the management of these diseases of the eye, hygienic and dietetic regulations are of the first importance. Fresh air, light, warm clothing, and good diet are indispensable always. In regard to light, I do not believe in keeping the patient in a dark room. If there is no ulceration of the cornea, no special attention in a hygienic way need be given in this affection to the patient's dread of light. The celebrated Professor Beer, who formerly had charge of the department of the general hospital for diseases of the eye during many years, in Vienna, used to take children affected with severe photophobia and place them in a position so that the sunlight might fall directly into the eye, and then force the lids apart. This appears like a very dangerous proceeding, but I have the authority of the grandson of the operator, the late Prof. Ed. von Jaeger, to the effect that no unpleasant effects followed the treatment. A rather heroic method, or one which mothers at least would consider so, was practised by Professor Graefe, 128 THE CONJUNCTIVA. in Berlin. When the eyes were better and yet the photophobia did not yield, he dipped the child's head under water, perhaps several times, thoroughly frightening it, and usually with the result of overcoming the spasm of the orbicularis. I have seen tartar emetic given to children, in London, for the purpose of making them sick and relaxing the orbicularis. A 2% solution of cocaine will often prove useful in such cases. When there is an ulcer on the cornea or a vesicle near its edge in the stage of excoriation, the photophobia may arise from the exposure of denuded nerve fibres; and then the progress in reproducing an epithelial covering for the exposed nerves will be very much hastened by bandaging the eye. The bandage will also serve the purpose of preventing friction of the lids in winking, lessen irritation and pain, and tend to prevent rupture of the cornea if it happen to be the seat of a deep ulcer. Children also have a disposition to constantly rub their eyes,-a trifling circumstance enough, but one which frequently has seemed to me a chief cause of the continuance of the inflammatory state, - and this the bandage of course completely remedies. This bandage should be changed several times a day, and the discharge washed from the eye, if discharge be present. Sometimes great pain and restlessness will be promptly relieved by dropping a 2% solution of cocaine into the eye; and its quieting influence seems to expedite the cure. A weak solution of atropine will often prove useful also, when the cornea or iris is involved. The atropine should never be dissolved in alcohol or alcohol and water, because alcohol applied to the eye is an irritant, PHLYCTENULAR CONJUNCTIVITIS. 129 and usually contra-indicated in cases where atropine is likely to prove useful as a sedative. It is almost, or quite, impossible to give even an outline of the treatment that may be required in scrofulous ophthalmia, because, aside from the different tissues of the eye which may be affected, the patient, so far as my experience goes, almost invariably suffers from general disturbance of the health. PHLYCTENULAR CONJUNCTIVITIS, or herpetic or pustular conjunctivitis, as it is frequently termed, may be considered as a phase of scrofulous ophthalmia. It occurs usually in children, and mostly in those of a so-called scrofulous diathesis, and very rarely in children otherwise in good health. It is characterized in its simple form by the appearance of a reddened point upon an inflamed base of the conjunctiva, slightly raised, and situated usually either at the limbus of the cornea, or upon the sclerotica near its junction with the cornea. This red point usually terminates in a vesicle, which, changing into a slight excoriation or ulcer, gradually disappears, and leaves no trace behind. There is generally some irritation of the ciliary nerves, and, as a consequence of this, some photophobia and lachrymation. These symptoms being greatly increased when the vesicle or vesicles happen to come on the cornea or at its limnbus. If the vesicles are not developed in too great numbers, and are not too near the cornea, the disease is very slight, and requires very little treatment. I was once consulted by an adult, in a case of herpetic conjunctiva,whose physician had in9 130 THE CONJUNCTIVA. formed him that he had probably a pterygium growing over the sight of the eye, and it would have to be removed by an operation. He was a sculptor, and I advised him to remain at home for a few days, so as to avoid the dust of his studio, and he was soon cured without further treatment. Many cases, however, are much severer than this and not as easily disposed of; and in all, the tendency to recur again and again is strongly marked. Treatment. The best remedy for this disease is the external application of powdered calomel. The inspissations of the powder should be made by taking up a minute quantity of the fine powder on a camel's-hair pencil, then holding the pencil vertically before the affected eye, between the forefinger and thumb of the right hand, having exposed the surface of the under lid with the left hand, tap the handle of the brush rather smartly with the ring finger of the right hand, at the same instant tossing the brush slightly towards the lids, and some of the fine dust will be projected directly into the eye. This manoeuvre is simple, but it requires a little practice to do it neatly. The calomel should be very fine, but little should be taken up on the brush, and no lumps of it thrown into the eye. Neither should it be blown into the eye through a tube; it is too coarse treatment for a delicate eye, though convenient for the nose or ears. The calomel seems to exercise a specific influence in these cases, due to its germicidal properties. I formerly thought the calomel simply an irritant used in this way, PHLYCTENULAR CONJUNCTIVITIS. 131 but am now convinced to the contrary. It does irritate, and should therefore be used cautiously if the eye is very sensitive and dreads the light. For the photophobia, tartar emetic will often be serviceable. Ciliary neuralgia may often be quieted by chamomilla, using at the same time warm fomentations of chamomile water over the closed lids. Very severe pain may be quickly relieved by the instillation of a two per cent solution of cocaine. The general treatment will be that indicated for scrofulous ophthalmia. Norton advises sulphur internally as specially serviceable, and directed to the constitutional symptoms so often manifested by an eruption similar to that of the conjunctiva, at the alt of the nose, angles of the mouth, behind or in the ears, and about other parts of the body. Sometimes a herpetic point appears in the subconjunetival tissue, just at the edge of the cornea. When this is the case, and the sclera or the episcleral tissue is involved, the progress of the disease is tedious in the extreme. I have had an example of this variety where one vesicle remained imbedded beneath the conjunctiva for more than three months. It is difficult sometimes in such instances to determine whether such a case should be regarded as a conjunctivitis or an episcleritis. See Phlyctenular Keratitis. Exanthematous conjunctivitis, occurring during eruptive fevers, does not usually demand special treatment. It is always present to a certain extent in measles, scarlatina, and variola. Any discharge should be removed, and the eyes should be protected against bright light. Bathing in tepid water, or milk and water, is 132 THE CONJUNCTIVA. often grateful, and if the edges of the lids adhere, or are tender or excoriated, the application of vaseline, olive oil, or glycerine will be useful. If the discharge continues, a collyrium of one or two grains of nitrate of silver to the ounce of water may be used twice a day. Pterygium is a hypertrophied condition of the conjunctiva, usually of a triangular form, the apex towards the cornea, the base at the semilunar fold. The growth is tendinous, and supplied with vessels. When red and irritable, rest of the eye, soothing applications like warm water, and bandaging for a few days will greatly relieve the condition. If it is not particularly annoying, and does not increase rapidly so as to threaten impairment of vision, by encroaching on the pupillary area, it is better not to disturb it, unless for cosmetic reasons the patient desires its removal. The operation is done by seizing the growth with delicate forceps and dissecting it from the cornea with a knife; then incise with scissors the conjunctiva from the upper corneal margin of the growth back to the centre of the base of the pterygium, and make a similar incision from the lower corneal margin of the growth and remove the lozengeshaped portion of conjunctiva between the incisions. The conjunctiva above and below is then to be loosened from the sclera and drawn over the raw surface and stitched. A variation in the operation is to dissect up the growth, then double it inward upon itself and confine it by a deep suture. The operation for its removal is not always permanently successful. A less severe form of the disease consisting merely of a slight hyper PINGUECULA. 133 trophy of the conjunctiva is readily and successfully removed with the forceps and scissors. The cause of the disease is usually some injury of the eye or exposure which irritates the conjunctiva, and it sometimes results from a phlyctenular or other ophthalmia. A warm climate predisposes to the affection. HEMORRHAGE BENEATH THE CONJUNCTIVA may be known by its bright red color, by its occurring in circumscribed, well-defined spots, often extending up to the edge of the cornea. It may be due to a blow or fall, but often no assignable cause can be found. When it appears in feeble elderly subjects it may indicate a weakness of the blood-vessels generally, and an attack of apoplexy of the brain. Usually it is far more alarming to the patient than hurtful; but in severe cases with recurrence of the bleeding, rest and bandaging the eye may be advisable. PINGUECULA. The little elevation of a yellowish color observed in elderly people at the margin of the cornea, called pinguecula, is not annoying except from its conspicuousness. If desired it may be seized with delicate forceps, and snipped off with the scissors. Warts of the conjunctiva may be treated in the same way. Cysts of the conjunctiva are to be treated similarly. Dermoid tumors, generally seated at the corneal margin, are best dissected out with the knife, care being taken not to go too deeply into the corneal and sclerotic tissues. CHAPTER VII. THE CORNEA AND SCLERA. FROM a clinical point of view keratitis may be divided into two distinct forms, -namely, the suppurative and the non-suppurative. The first involves loss of true corneal substance and more or less impairment of sight. The second may result, and often does result in perfect restoration of the normal transparency of the cornea. PHLYCTENULAR KERATITIS. The cornea is frequently the seat of excoriation or ulceration in the vesicular or phlyctenular variety of scrofulous ophthalmia. The objective symptoms are those of phlyctenular conjunctivitis more strongly marked, with much greater ciliary irritation, congestion, and photophobia. The vesicles, often situated at the corneal edge, are small grayish points which usually rupture and leave minute superficial ulcers. The affection belongs essentially to the period of childhood. A similar disease appears as a Fascicular keratitis in which vessels run near each other in parallel lines over the corneal limbus on to the PHLYCTENULAR KERATITIS. 135 cornea to supply material for the repair of the ravages of the small corneal ulcer. See Fig. 23, after Nettleship. FIG. 23. Superficial vascular keratitis is still another form of scrofulous affection of the cornea, characterized by the formation of a network of vessels over a circumscribed portion of the cornea which, in the affected region, is more or less infiltrated and roughened. This condition may be the result of repeated attacks of the phlyctenular variety of keratitis. Treatment. The treatment of phlyctenular keratitis should, in general, be that laid down for scrofulous ophthalmia on page 126. Arsenic and mercury as internal remedies are prescribed by me perhaps oftener than others; but iron and good feeding are often necessary, and the best possible hygienic conditions should be secured. As for the external treatment, the ciliary irritation is so great that considerable caution is necessary. Powdered calomel is not well borne. A half or quarter per cent solution of atropine once a day is soothing, and a two per cent solution of cocaine for pain and photophobia 136 THE CORNEA AND SCLERA. three or four times a day may be used. A solution of bi-chloride of mercury 1:10000 should be dropped in the eye as an anti-septic; if it irritates it may be used directly after the cocaine. If it prove too irritating boracic acid, one per cent, may be substituted. As the acute symptoms subside, one may use an unguent of four to six grains of the yellow oxide of mercury to an ounce of vaseline once or twice daily; but this often proves too irritating, and hot water fomentations may be equally serviceable. The water should be as hot as can be borne, and the small compresses which are to be placed over the closed lids should be changed every few seconds. These fomentations should be kept up for five to ten minutes three or four times a day, and as the acute symptoms subside, from ten to twenty minutes at one time. In the beginning the eye should be bandaged for reasons given at page 128; but later, as the eye improves, the bandage may be discarded as tending to keep up the photophobia. Vesicular, or herpetic, keratitis is rather rare. Sometimes a cluster of minute vesicles filled with transparent liquid are present on the cornea, and after catarrhal affections similar herpetic eruptions appear about the mouth and nose. The treatment is that for phlyctenular keratitis. Bulbous keratitis is caused usually by injury of the cornea. The epithelium is raised and forms a rather large fluctuating vesicle filled with a transparent, and more rarely with a purulent, fluid. The detached epithelium should be removed under cocaine. The disease DENDRIFORM KERATITIS. 137 is liable to recur. A somewhat similar condition is found after old affections involving tension of the eyeball, but the disease is then due to cedema of the cornea and is not amenable to treatment. Dendriform keratitis is a very superficial ulceration of the cornea extending across it in the form of a branch or twig. It is best seen by lateral illumination. In a recent case, that of a young man of twenty-three, otherwise perfectly healthy, there was a good deal of photophobia but not much pain. Under cocaine I scraped the ulceration gently at first, then applied a solution of bi-chloride 1:5000 and bandaged the eye. The pupil was kept large by atropine, and he used a solution of bi-chloride 1:10000 three times a day. After three weeks the bandage was left off. He came to me on April 21, and was last seen on May 24, when there was no photophobia remaining, although traces of the ulceration were still faintly visible. Sight 20. Vascular interstitial keratitis may be considered as a severe, deeper-seated form of fascicular keratitis. The treatment should be similar, and in uncomplicated cases the prognosis is favorable. Non-vascular interstitial keratitis in which one or more circumscribed infiltrations appear in the cornea gradually growing more opaque, may supervene from a vascular keratitis, or from some form of conjunctivitis, or may be due to some unknown cause. The prognosis is good; but the progress towards health may be very slow. Hot water compresses applied as directed at page 136, to be regulated as to frequency and time according to the reaction produced. It may be necessary to use the 138 THE CORNEA AND SCLERA. hot water for a half hour three times a day. Atropine may be used to keep the pupil dilated and avoid iritic complication, and the general health should be guarded by proper hygienic and remedial measures. Diffuse interstitial keratitis is of inherited syphilitic origin usually. It is sometimes possibly due to scrofulous diathesis, and a few observers believe that it may follow acquired syphilis as a secondary manifestation. It is often seen in children with the characteristic notched teeth of inherited syphilis. See Fig. 26, p. 157. A slight grayish opacity of the cornea is first noticed, and this gradually increases in density until vision is reduced to mere counting of fingers near the eye. In uncomplicated cases the prognosis is favorable. The cornea usually becoming clear again after some time. I have always used atropine in these cases, and given mercury and iodide of potash internally, but have never been certain that the treatment influenced the course of the disease, which is invariably slow. The past year I used hot fomentations in the case of a boy of fourteen, and the result leads me to think it possible that the application of heat may hasten the absorption of the infiltration. L. R. came to me May 4. V. R. saw fingers near the eye. June 1. V. -2 0. July 5. -. Meantime the left eye became similarly affected in June, and grew gradually worse until July 5, when it began to improve. The boy was entirely recovered when I returned from my summer vacation in September. Here the disease was, in the right eye at least, of less than three months' duration. Keratitis punctata superficialis, as described by Fuchs, SUPPURATIVE KERATITIS. 139 is a form of keratitis following an acute catarrhal conjunctivitis, and characterized by unusual ciliary irritation, pain, and photophobia. It is apt to recur, and then little dots are observed about the centre of the cornea, the marginal portion remaining clear. The dots are in the superficial layers of the true cornea beneath Bowman's membrane. The prognosis is good, but the course of the disease is very slow. It is most conmon to those between ten and twenty years of age. The treatment would be similar to that of a severe phlyctenular keratitis. Deeper-seated affections of the cornea are keratitis punctata, secondary to disease of deep-seated affections of eye, see page 158. Suppurative keratitis, which is sometimes met with as a result of severe purulent ophthalmia or from chemical or mechanical injury to the eye, or from surgical operations in the corneal tissue, is a grave form of the disease leading to ulceration. It is frequently accompanied by severe ciliary neuralgia. The rose-colored zone around the cornea, contraction of the pupil, and sometimes chemosis are present. We notice a gray opacity, which changes afterwards to yellow as the tissues become broken down, and the end may be a perforation of the anterior chamber. Or there may be extensive corneal abscess, perhaps interstitial infiltration forming onyx. Or a hypopion may result from precipitation of pus to the bottom of the anterior chamber (hypopium keratitis). See Fig. 24, from Nettleship, on the next page. The matter may reach the anterior chamber from extension of the suppurative inflammation to 140 THE CORNEA AND SCLERA. the iris without perforation, or more usually from bursting of the posterior layer of the cornea. The elastic layer of Descemet is not subject to the suppurative process. Suppurative corneitis is very readily produced by injuries of the cornea in the aged or weak, and is not unfrequently met with as a sequence of typhus, typhoid, cholera, or diabetes. An indolent or non-inflammatory form of corneitis, where the FIG. 24, absence of pain and irritation is a characteristic feature, is of still more dangerous nature. In neuro-paralytic corneitis the infiltration sometimes extends with great rapidity; and necrosis not only of the whole cornea ensues, but in rare instances the suppuration extends to the entire globe. All suppurative forms of keratitis, since the loss of corneal substance is involved, leave permanent opacities and more or less impairment of vision. All are probably due to infection; if not from without, then through the circulation from within, and this fact should of course influence our local treatment. TREATMENT OF CORNEITIS GENERALLY. The treatment of corneitis occurring during the course of the various ophthalmia has been sufficiently indicated. In the severe suppurative forms the eye should in the first place be bandaged, and the flannel band should be long enough to pass twice around the head, so that considerable pressure may be exerted on the ball of the eye. Pressure seems to have a controlling influ SUPPURATING INTERSTITIAL KERATITIS. 141 ence in limiting the extent of the suppuration, and every hair's-breadth of transparent cornea saved to the patient multiplies infinitely his visual power in the end. If the inflammatory symptoms are so marked as to indicate the cold compress, then the application of the compress bandage may be alternated with the use of cold water. It is hardly worth while to attempt to combine the cold and the compress at the same time. One or the other will be pretty sure to be inefficiently attended to. In the non-inflammatory form of keratitis, hot water fomentations of a temperature from ninety to one hundred Fahrenheit are indicated, the object being to create inflammatory reaction. The same treatment for the same object is serviceable in all forms of corneal affections if the inflammatory appearance is lost and resolution still doubtful. These fomentations are very potent agents for good, or, when indiscreetly used, for evil, and their application should not therefore be intrusted to other than trustworthy attendants. When a marked injection of the eye has been induced, they should be temporarily discontinued. Paracentesis is sometimes resorted to as a relief from intra-ocular pressure, to preserve the integrity of the cornea, and sometimes for the evacuation of hypopion or interstitial matter. Cocaine will often relieve pain. Myotics must'be used with caution as tending to ciliary irritation. Atropine is usually advisable. SUPPURATING INTERSTITIAL KERATITIS. This outline of a case of apparently total destruction of the cornea from suppuration, as I at first considered 142 THE CORNEA AND SCLERA. it, may be instructive as showing the value of paracentesis combined with the application of heat in certain cases. On June 7, 1879, Capt. B., aged sixty, master of a whaling vessel, was brought directly from his ship to my office. IHe had sailed some six weeks previously, with good sight, but off the coast of South Carolina had been attacked with inflammation of the eyes, had gradually become blind, and was obliged to bring his vessel back to port. He was led to my house as a blind man, but I found vision, left eye ten two-hundredths, right eye entirely blind; he thought he could distinguish the direction of a window in the sunlight, but failed to detect the presence of a sheet of white paper moving before the affected eye. There was diffuse cloudiness of the whole cornea in the left eye, but it was not sufficiently dense to completely hide the iris and pupil. The conjunctiva was moderately injected around the corneal edge. The right eye presented a very different aspect. There was deep, dark injection of the entire ocular conjunctiva with chemosis; the cornea was yellow and opaque; the infiltration of pus between its layers was so marked a feature that I looked for its disintegration very shortly. The patient was assured that the left eye would probably be restored to fair sight, but was told that the right was inevitably lost. I instilled atropine into both, bandaged them, gave orders for a hot fomentation to each, of fifteen minutes three times a day. Gave him quinine,?o- five grain doses, three times a day. The quinine was suggested by his general health, which, although not specially bad, was not up to his usual robust standard. June 9. Left eye better, cornea clearing a little. The right eve is not changed in appearance. He cannot see a white paper moving before it. Made a small opening into the anterior chamber at the lower corneal margin with a Beer cataract-knife, which I consider the best instrument for this purpose if used cautiously. There was a discharge of aqueous followed by SUPPURATING INTERSTITIAL KERATITIS. 143 aqueous turbid from pus, showing that hypopion probably existed also, but undetected owing to the complete corneal opacity. Treatment continued. June 11. Left, better. Right can see a white paper before the eye owing to a little clearing up of the cornea at its inferior edge near the opening. Paracentesis again. June 13. Left, improving. Right, about the same. Paracentesis. June 16. Same. But the chemosis, which had been lessening, is now more marked above the cornea, and there appears to be a more dense infiltration of pus in that part of the cornea near it. Paracentesis. Use the hot fomentations for fifteen minutes only once a day. June 18. Right eye less chemosis. Paracentesis. June 20. Right, again clearing up a little. Paracentesis. June 28. Right, better. Saw, near the eye, the large letter C number 200. June 30. Right saw letters number 100 near the eye. July 2. Improvement has ceased. Fomentations twice a day. Paracentesis. July 5. Right eye better again. Sees letters number 70. July 10. Right sees letters numbered 30 near the eye. July 14, 16. Record is the same. The patient left Boston for his home a hundred miles away. His left eye had so far recovered that with D + 1.25 he could read print number 8 comfortably. The distinction between a suppurative process in the cornea and some forms of ulceration is by no means clear, and the above case resembled somewhat the creeping ulceration of the cornea called the serpiginous ulcer. In a case of this kind now I should make free use of a wash of bi-chloride of mercury and probably use other anti-septic measures. Aconite, internally, is the remedy to be employed 144 TIIE CORNEA AND SCLERA. when the reaction is sufficient to warrant the application of cold to the eye, afterwards the remedies must be chosen with reference to general condition of the patient, never neglecting the digestive functions and a nutritious diet. Pain is best controlled by cocaine instillations and hot fomentations. In cases due to hereditary syphilis (diffuse corneitis) Norton advises aurum internally. ULCERATION OF THE CORNEA. Corneal ulceration is nearly always an indication of impaired health and weak vitality. There is always more or less congestion of the conjunctiva, and generally pain, lachrymation, and photophobia. Strumous ulceration, not as the sequence of a vesicle, deeper, and nearer the centre of the cornea, occurs in scrofulous ophthalmia, beginning as an opaque speck. The Ulceration in ophthalmia neonatorum is similar to this in appearance. A grayish opacity, its centre nearly transparent, the gray then giving place to a tinge of yellow, and this, as resolution sets in, changed again to gray. A blood-vessel, or leach of vessels, may often be seen to run from the sclerotic to the ulcer. Transparent ulcer of the cornea is sometimes observed, in which the vision of the patient, instead of being clouded, suffers only from the irregular refraction of rays of light in passing through the uneven portion of the cornea. All objects appear distorted. The above are generally superficial ulcerations. Among the deepseated ulcerations, the THE DANGER FROM ULCERATION. 145 Crescentic ulcer of the cornea, as described in the details of the case of gonorrhceal ophthalmia, is one of the more common, while the Sloughing ulcer, from suppurative corneitis in the weak and ill-fed, and the analogous indolent ulcer seen in the aged, frequently complicated by hypopium and iritis, called the creeping ulcer (ulcus cornea serpens), probably of infectious origin, and sometimes due to injury of the cornea, are fortunately more rare in private FIG 25 practice. See Fig. 25, after Nettleship. Both these forms are very dangerous. The same may be said of a still more rare and fatal form, the neuro-paralytic, due to paralysis of the fifth nerve. THE DANGER. The chief danger of ulceration lies in the tendency to leave a more or less opaque scar or cicatrix in the corneal tissue, which, if it happen to be situated in or near the centre of the pupillary area, renders vision imperfect. Another danger lies in the direction of a perforation of the cornea, which may occasion a prolapse of the iris, resulting in adhesion between the iris and cornea, displacing the pupil, or distorting it, and perhaps engendering an iritis, or, if the perforation happen to be small and central, causing a deposition of matter on the surface of the lens capsule, or capsular cataract. 10 146 THE CORNEA AND SCLERA. TREATMENT OF CORNEAL ULCERATIONo One of the most potent local measures for promoting a speedy healing of a corneal ulcer is a protective bandage. It is just as essential that the exposed surface of the cornea should be protected from the air, as that any other portion of the body, under similar circumstances, should be covered artificially. The quicker a fresh layer of epithelium is formed to cover the denuded nerve fibres, the sooner will the photophobia vanish. Place a single thickness of fine muslin over the closed eye, then fill the orbit, especially at the inner angle, with fine charpie, or absorbent cotton, so that the band of elastic flannel may press uniformly, but gently, upon the whole eyeball, just sufficiently to prevent winking. It has been found serviceable sometimes when an ulcer threatens perforation to anticipate the rupture by puncturing it with a fine needle. The advantage of this is that the opening made is very small and regular, the aqueous humor flows off gently, and the iris, falling against the opening, adheres over a very minute surface, and when the aqueous humor once more accumulates, it will be quite likely to be torn away uninjured, and there will remain as a sequence of the disease but a small corneal opacity. Sometimes a perforation has been prevented by a paracentesis of the cornea at its edge, which relieves temporarily the intra-ocular pressure. In perforation it is of course advisable to prevent the iris being involved, if possible, and to this end the pupil should be kept widely dilated by atropine when the ulcer is situated centrally. If the ulcer is towards TREATMENT OF CORNEAL ULCERATION. 147 the margin of the cornea, eserine or pilocarpine may be substituted, in order to contract the pupil as much as possible, and draw its edge away from the seat of the threatened breach; but eserine and pilocarpine are to be used tentatively as they are often ill borne. Pain and photophobia are to be relieved by removing the bandage and using very hot water fomentations, or by the instillation of a two or four per cent solution of cocaine. The diet, in cases of this kind, ought to be as nutritious as the condition of the digestive organs will permit. Fresh meat should be prescribed, and the child should be kept in the open air as much as possible. No darkening of rooms should be permitted; on the contrary the sun should be allowed free access to the nursery, and welcomed as one of the best auxiliaries to the treatment. The dread of light is of course provided for by the bandage, which prevents access of all light, as well as air, wind, dust, smoke, and all deleterious external influences. In some instances of chronic, indolent ulcerations, heat, either dry or in the form of hot fomentations, is found to hasten a cure admirably. It is well to make the hot fomentations anti-septic by the addition of the bi-chloride of mercury. The examination of an ulcer on the cornea is much facilitated by lateral illumination. This gives us a correct idea of the depth, extent, and progress of the ulcer. When the ulceration occurs in the course of a granular or purulent ophthalmia, such applications as are necessary for the cure of the diseased conjunctiva are to be made as previously directed, care being taken that no irritating substance comes in contact with the cornea. 148 THE CORNEA AND SCLERA. In certain indolent ulcerations a direct stimulating or anti-septic or germicidal treatment has been found useful in practical hands. The actual cautery or the galvano-cautery is applied to the ulcer. Or the ulcer is scraped and nitrate of silver applied. Or the ulcer is slit through its entire length with a Graefe cataract knife (Saemisch operation), or an iridectomy is done. But in spite of any and all treatment, deep-seated ulcerative processes in feeble constitutions often go on to fatal results so far as sight is concerned. The internal or general treatment in ulcerations of the cornea must look to favorable hygienic conditions, good feeding, and the constitutional dyscrasia. Mercury and sulphide of calcium are accredited with a power of limiting suppuration, and arsenic is of acknowledged efficacy in debility and weakness. Whatever our internal remedies may be, the promotion of the appetite, digestion, and assimilation must not be lost sight of. I have recently treated, in an adult, an ulcer of the cornea, following an acute syphilitic affection of the genitals. The cure was speedy and complete under biniodide of mercury internally, and the use of the bandage and the instillation of atropine, as auxiliaries. STAPHYLOMA ANTERIOR. Staphyloma of the cornea and iris sometimes occurs as a sequel of perforation or sloughing of the cornea. The iris falls against the opening, lymph is secreted and a cicatricial tissue, something of the nature of opaque cornea is formed. Being weak and inelastic under STAPHYLOMA ANTERIOR. 149 intra-ocular pressure, it bulges forward, and forms a partial or total staphyloma of the cornea and iris. The disease is to be treated surgically. The intra-ocular pressure is most certainly relieved by iridectomy beneath that portion of the cornea which still retains transparency, so that the operation may serve at once the double purpose of improving sight and removing pain and disease. This presupposes the staphyloma to be only partial. When it is total, the bulging of the eye is so considerable as to present an unsightly appearance; it is irritable, painful, and all sight inevitably lost. In such cases the best thing to do, it has always seemed to me, is to remove the eye. Excision of the staphyloma involves too great risks; but lately De Wecker advises repeated punctures of the sclera in the vicinity of the equator. Conical cornea, a transparent bulging at the centre, is most readily diagnosed by noting the difference in the size of the image of the window on the two corneae, or by viewing the eyes in profile. It may also be recognized by the ophthalmoscope. By direct examination we see a central red illuminated space, around this a dark zone, and still outside of this a red ring of light. The dark zone is occasioned by the complete reflection and diffusion of the rays of light at the base of the central cone, where it joins the normal cornea through the periphery of which the outer red ring of light is reflected. One may also get an inverted image of the fundus of the eye, as in myopia, in consequence of the increased refractive power of the centre of the cornea. The bulging is not due to intra-ocular pressure, for the 150 THE CORNEA AND SCLERA. eyeball is softer rather than harder than in the normal condition. It seems to be due rather to a thinning and weakening of the corneal tissue. The progress of the disease is generally slow. The increased curvature of the centre of the cornea renders the eye myopic, and there is irregular astigmatism. Concave, spherical, and cylindrical lenses may afford measurable optical correction, and sometimes hyperbolic lenses are useful. Surgical aid may be tried as a last resort and, when there is opacity at the apex of cornea, there is less to lose if an operation prove unsuccessful. Trephining, or removing a portion of the corneal apex, and an iridectomy may be of more or less benefit. Hirschberg perforates the apex with the actual cautery, following it later by an iridectomy. Arcus senilis, a line of opacity extending partially or entirely around the periphery of the cornea, caused by fatty degeneration, requires no treatment, as it produces no visual disturbance. Opacities of the cornea, resulting from previous disease of its tissue when slight and recent or when dense, the edges not sharply defined, and, in children, usually disappear in course of time without treatment. After all irritation of the eye has subsided it is possible that the use of stimulating collyria may hasten this result. A solution of two grains of sulphate of copper or zinc, or five grains of alum each to the ounce of water may be used once or twice daily. But I prefer usually the stimulating effect of hot fomentations of water, used for fifteen minutes or longer, night and morning. Whatever agent we may use to promote local reaction should STAPHYLOMA ANTERIOR. 151 be changed from time to time as the eye becomes tolerant of it. Internal treatment should look to the improvement of the general health, I think. Calcaria, cannabis, sulphur, and a multitude of other internal remedies are accredited with having hastened the removal of these corneal opacities. When an opacity is old, and has assumed a white, pearly, glistening appearance, its margin well-defined, and especially if in an adult, we shall fail in any attempt to remove it either by internal or external means. We have then the resource of an artificial pupil, to be made exactly behind such part of the cornea as retains most of its normal transparency. We may also resort to the operation of tattooing the cornea. The coloring matter, usually India ink, is pricked into the cornea with a needle or delicate knife, and not only hides the unsightly opacity, but may improve vision in some cases by lessening the diffusion of light, just as the small aperture in stenopaic glasses, and the pin-hole in a card, render vision more acute. Nussbaum, of Munich, some years since, tried the plan of removing the central'portion of an opaque cornea, and inserting a circular window of glass. It was not successful; suppuration and expulsion of the glass followed. The operation of transplantation of cornea has also failed. It is always melancholy to be consulted by a patient, the interior of whose eyes is perfect, and who could see, if only the foggy cornea could be replaced by some transparent medium, and be obliged to tell him that there is no hope left for sight. It is not unreasonable to believe, I think, that the future of 152 THE CORNEA AND SCLERA. surgery will provide some remedy, more or less complete, for these unfortunates. EPISCLERITIS. Episcleritis begins in the form of a dusky-red circumscribed spot, beneath the conjunctiva in the episcleral tissue or superficial tissue of the sclerotic, generally near the edge of the cornea. As it progresses, the color usually changes to a purplish hue, and there is more or less bulging. It causes a good deal of ciliary irritation and neuralgia, if it involves the edge of the cornea. Otherwise, there is slight or no pain and little injection of the conjunctiva. It is most common in adults, and is then no doubt a rheumatic or gouty affection. It is of not unfrequent occurrence in the course of a scrofulous ophthalmia, and accompanied by a conjunctivitis and some slight mucous discharge. It must not in these cases be confounded with a vesicular or phlyctenular ophthalmia. No ulceration or excoriation ensues, but the spot or nodule gradually pales away. The immediate cause of the affection in adults is generally debility from overwork, or some depressing influence. It is not difficult to relieve or cure, when the patient can be thoroughly under control. Warm fomentations are always soothing, and atropine or cocaine, when necessary, will quiet the ciliary neuralgia which is apt to come on at night. All use of the eyes is to be prohibited, and a shade worn when in the open air. Constitutional disturbances will generally indicate the choice of internal remedies, otherwise I rely almost wholly upon the protiodide of mercury, which has SCLEROTICO-KERATITIS AND IRITIS. 153 seemed to be very serviceable. An examination of the urine will often suggest the internal treatment. Gentle massage, for a minute or two, through the closed lids once or twice a day when the eye is not too sensitive is useful. An unnatural bulging of the sclerotic often occurs as the result of old choroiditis or irido-choroiditis. It is not unusual in cases of glaucoma. It is situated commonly at the anterior part of the sclerotic behind the ciliary region, and is called frequently anterior staphyloma in distinction to a posterior staphyloma of the sclerotic seen in progressive myopia. The disease is not idiopathic, but supervenes upon inflammation of some portions of the uveal tract, and presents no characteristic features except in the bulged and bluish appearance of the thinned sclerotic. The treatment will be directed to the iris, choroid, or ciliary body. If there is increased tension of the eyeball, operative interference may be indicated. Sclerotico-choroiditis posterior is noticed under Myopia. SCLEROTICO-KERATITIS AND IRITIS. The bulging of the sclera anteriorly may also occur, exceptionally, as a result of an inflammation in the ciliary region which appears to include both cornea and iris, as well as the sclera. The dusky purplish color, already spoken of as characteristic of scleritis, may circumscribe the entire cornea, or not. There is generally considerable pain and photophobia, and the affection is persistent and often relapsing. The edge of the cornea near that part of the ciliary region most affected be 154 THE CORNEA AND SCLERA. comes cloudy or opaque. The treatment in these cases must be similar to that already given for ordinary episcleritis, except that the use of atropine in the affected eye is imperative on account of the iritis. The prognosis, on the whole, may be said to be favorable. CHAPTER VIII. THE IRIS. HYPERZEMIA OF THE IRIS PRESENTS symptoms similar to those of simple iritis, except that they are less marked, and the exudation is absent. It may be caused by over-exertion of the eyes for near objects, and often indicates a congestion of the deeper-seated structures of the eye. It is frequently noticed in scrofulous ophthalmia, and is not unfrequently one of the results of an injudicious use of caustics. The treatment will depend upon its course, and the nature of the associated affection. Generally it will require a treatment similar to that for iritis. SIMPLE IRITIS, OR RHEUMATIC IRITIS. The objective symptoms are injection of conjunctiva, also sub-conjunctival injection, the rose-colored zone around the cornea being well marked; generally there is contraction of the pupil, and always sluggishness in dilation and contraction, discoloration, - a blue iris becoming greenish, and a brown iris reddish-brown, - and there may be observed frequently a plastic exudation at the pupillary edge or on the surface of the iris. The pupil is usually irregular in form, its lower edges adhering to the lens capsule behind it. In severe cases 156 THE IRIS. there is sometimes swelling of the lids, injection of the conjunctiva, chemosis, and the posterior surface of the cornea may be mottled by minute depositions of lymph. The subjective symptoms are sometimes merely dimness of vision and slight dread of light. At other times we find them very severe; there is great pain in the eyeball, around the orbit, and in the temple, generally worse at night, severe photophobia, and lachrymation. Acute iritis is frequently accompanied by a diffuse retinitis, and sometimes by hyalitis. It is advisable, therefore, when the aqueous is sufficiently clear, to use the ophthalmoscope to determine whether such complications exist. Gonorrhoeal iritis, occurring during the course of a gonorrhoea, is similar to the rheumatic, but, unlike this variety, usually attacks both eyes at or nearly at the same time. SYPHILITIC IRITIS, the symptoms of which correspond generally to those above given, is a deep-seated form of inflammation, the tissues of the iris becoming swollen and thickened. In syphilitic iritis the exudation is usually copious, the swollen tissues of the iris impede circulation, the vessels become congested, and tortuous veins appear on the face of the iris. Observation by lateral illumination will be of help in noting the structural changes which occur. Little yellowish nodules may often be seen about the edge of the pupil, the mischievous purpose of which seems to be to stick the edge of the pupil firmly to the capsule of the lens. The aqueous humor becomes increased in bulk, and turbid from the admixture of pus 7 F2. 20. This itltstration, from XNettlehlip, 8hows the apptearat.ac e of the -lermaXlalent tseect IT IntstAlnees whore the enanel is s'antim.g or ts n:eriycrfct. The uplper figure p}reselt-s an ultinaily a;.. exanmple. Generally th. defrectives enanrel is ntoticed: only at the cedge of thte tcisoars, a.s in- tie'e:tmainintg figures. tSuch teeth are often fountl il dliftu.ao keratfitis, Erous irltis, etc, T1IiS mItmS, anld li.nmlph th rown out by the iris. The latter is somel times compleltely covere( d by a thin veil of exudationt so as to be, quite indistinct., andt the exutdatio on ay be so extensive ast to settle at: the brottol of the anterior clhanber', Jtorntming a hypopiinm. In ttis formnt of iritis lth(re tare alsi frequently the tuhberculots nodules ont certain porltions of the iris, reddish-yel ow\ in color, and wtli}ch attt:ain often to c. ositderabl size, and may even project so far into ithe chamb.lt )er as to touch the posterior surface of the cornea.. never saw these contdylotmatous nlodes in a n onltl-syphlilit.ic case; sucol inllst-ances ha.ve, ehowever, }been. O brvd I t ts81 tstal l these nodies d(etermine thel,natture of t(he case. Still, in some instances, it is im1possible to r cognize a syphilit ic iritis )by the ilspection of the eyve talone. A 8 E RtOU t I I XTS is a chronic affection more coln)l mm lon iln \womlen tlhant mcn, insiidious and less painfhil tlitln tthe plastic f,'ormts of iriti s..' cTh rc is increas(e secretion of tlh a. iqucous lthumor, Awhictl is turblid atnd de(. / 14 ff )sS~ts~s,.posits, small secks of lymph 9/1\ ( Q> mt"pon tthe ptosteriort surfac:(tte of the 0'... ~:-.:..co(rnea; htence the affetction thas been called kerattit;is -,.n.fetat:a. It is'frequently associated with Fjro, 27. choroiditilt, a cyclitis, a,and the ptrognlos'is is not as favorable as ill moltst other ftorms of ir itis. Thcere is apt to hbe a'n increase of tension, and tlherefor: e atropine may not always be used as freely as would be desirable. It is often, also, a cor DIAGNOSIS OF IRITIS. 159 neo-iritis, and then the prognosis is less unfavorable. See Fig. 27, from Nettleship. DIAGNOSIS OF IRITIS. This is made comparatively easy by a careful observance of the objective symptoms already mentioned; still, in certain cases, some of these are more or less masked by the great injection of the conjunctiva, and some may be absent. Thus, the pinkish zone around the edge of the cornea may be hidden from sight by the vermilion redness of the congested conjunctiva. In such cases a general practitioner, I have observed, may mistake the disease for a conjunctivitis, and this may lead to the prescription of an astringent eye-wash, which is always contra-indicated in an iritis, and always aggravates the severity of the affection. Or it may lead to the neglect of the use of atropine or some other mydriatic, a mistake too often deplored after an eye is lost. But in these doubtful cases, if the physician will take his patient near a window, and test the movement of the pupils as directed at page 28, he will find a sluggish movement of the iris, if iritis be present; but if the movements of the pupil in contraction and expansion are active and natural, he may be quite sure that he has not an iritis. If in doubt still, he may drop a four-grain solution of atropine into the eye and observe if the pupil dilate evenly or irregularly. If the pupil is irregular in form there are adhesions and iritis. When there are elements of uncertainty in the case, avoid all irritating applications, and then, at least, no harm will ensue. If it is an iritis, it will develop unmistakably in a short time. 160 TXI: E I;RIS. fTHE CAUSE OF -It' nus is frequen tly r the exposure to changes of t Cemperature, cold rain. Awi'l, and like influences.'Th e sa-te (tcau.ses \which t.end to develop a rheumattic atttack, often occasion it.'the pain often extends over the whole of one sidef of tlb headtd aCin:d facet, and the patient is apt to suffer fromt relatpses. Jilt is frequently of tlaumatic origin (traumattic iritis), and frtequently olf s:iphiltitic. Most tases of idiopathic iritis ill childreln are ptrobably of syphtilitic origint, A. chrllntin c iritis, tholugh not verv often seen apartl from a choroi-:::.. ditis, may sutpervene upon an acute attack.,7The prognosis qf the disease when seen in the beginn-ing8 fbefore... ext..tensive adh esions. between the iris and cap:suloe of tle lens have formed, is veryt favorable. In unfa.,/;, vortable cases the result may be motre or ess extensive adhesion of iris to the anterior capsule of the lens. When tlhe ad2- 8,s. lhesion is complete 1around the edge of the pupil, the usual channel of communicat:i o between the posterior and anterior chamlber of the aqueous -is cut off and the iris bultges. See Fig. 28.'Thl. e.Frenchl call this condition "Iris b:)oml:llnt Without surgical interference stuch condition miglht end in secondary glaucoma. Partial adhesions are of less import than was fornerly supposed. I have under observation a p)atient that: was unintell itently treated some t wenty years ago; adhesions nearly complete; pupil occluded by a membrane; there is no sigrht in THE CAUSE OF IRITIS. 161 this eye, but it has never troubled her during all this time, and the sight of the other eye is perfect. The Treatment. The treatment should, in the first place, look to the prevention of these adhesions by the enlargement of the pupil to the full extent by atropine. This can never be safely neglected. For this purpose it should be used of the strength of four grains to the ounce, and be dropped into the eye at intervals of five minutes three or four times, morning, noon, and night. Less frequent use than this will sometimes keep the iris dilated to its maximum, but not always. In mild cases a drop or two once a day will often suffice. Another benefit of the use of atropine is that it gives the infamed muscular tissue of the iris perfect rest through the complete paralyzation of the constrictor pupille. When, as may sometimes be the case, the eye does not bear the continued use of atropine well, an atropine conjunctivitis, so called, being set up, an efficient substitute may be found in Duboisine. Sometimes recent adhesions have been broken up quickly by the alternate use of a solution of atropine and calabar bean, thus producing extreme alternate dilation and contraction of the pupil; but this should not be attempted if acute symptoms are present, as the eserine would prove too irritating. For internal medication I rely chiefly on aconite and belladonna in the beginning; later, the cause, and the condition of the patient must determine the treatment. Pain must be relieved, and hot water fomentations supplemented by cocaine instillations will usually do this. 11 162 THE IRIS. Syphilitic cases will be benefited by mercury and such other remedies as may be approved by the attending physician. Gouty and rheumatic patients must have the constitutional remedies suited to such diatheses. I have often given salicylate of soda in these cases, and sometimes bryonia or colchicum; and I think the hot fomentations several times a day after all pain is gone are effectual in subduing the inflammation. The patient should be confined to the house and his room, even if the attack be not severe. The darkened room will not be so necessary if atropine be used, still in all cases it will be more agreeable to the patient to have the bright yellow light moderated to a certain extent. When necessary for the patient to go out, he should wear a shade. In chronic iritis, when adhesions are left and irritation of the iris is kept up by them, a strong mydriatic being of no avail in breaking them up, the operation of Corelysis 1maxy be indicated. After ascertaining the exact position of the posterior synechiae by lateral illumination, a small incision is made through the cornea with a needle, and a blunt hook - called, from its form a spatula hook — is introduced, and the adherent iris separated from the lens. The great danger in this procedure, as indeed in all such operations on the iris, lies in the difficulty of avoiding the rupture or incision of the capsule of the lens. The operation of Passavant, in which the iris is seized by delicate forceps, and gently broken from its attachments, is preferred by some. Often an iridectomy will prove more serviceable than either, especially if increased tension be present. PROLAPSUS OF THE IRIS. 163 A chronic iritis, or irido-choroiditis, may sometimes be mistaken, at first, for a glaucoma; the diagnosis is corrected in such an event by testing the extent of the field of vision. If glaucoma is present we shall generally find it limited. Choroido-iritis is an affection primarily of the choroid, the iris being involved secondarily. The prognosis in the latter is more unfavorable; for while in the former an obscurity of vision may be due to a deposition of matter or pigment upon the capsule of the lens, in the latter it is due to changes in the deeper structures of the eye. The medical and hygienic treatment of these cases will be that of iritis and choroiditis. PROLAPSUS OF THE IRIS frequently occurs from perforation of the cornea from ulceration or otherwise. If slight, we may succeed in replacing it with a delicate probe, or, by enlarging the pupil with atropine, it may be pulled away from the gap. In any event the eye should be covered by a firm compress bandage, to prevent increase of the protrusion. If the prolapse is rather large and bulged outward from the aqueous humor, it should be pricked with a needle, causing it to shrink and dwindle away gradually. It may sometimes be necessary, after pricking it, to cut it off with scissors close to the cornea, to prevent its refilling. It should never be touched with caustic, according to the custom of some surgeons, as it causes great irritation, and may set up an iritis, and because under any circumstances it is quite an unnecessary risk to run. 164 THE IRIS. CYCLITIS. Cvclitis, or irido-cyclitis, may arise from a severe form of iritis in which there is an irrepressible tendency to cell proliferation, so that the disease soon reaches the ciliary bodies, or from injury of the eye. The inflammation in the ciliary body, when not idiopathic, corresponds in character to the nature of the iritis from which it originates. It is recognized by the tenderness of the eyeball to touch in the ciliary region, and it is generally the occasion of a good deal of ciliary neuralgia. Its treatment in the main is that given for iritis. It may arise also from the extension forward of a choroiditis, and would then require the treatment principally of a choroiditis. It is always a serious complication, and our prognosis should be guarded. It is noticed further under Sympathetic Ophthalmia. ARTIFICIAL PUPIL. The formation of an artificial pupil is indicated when the natural one has become closed by disease, and also, when, the pupil being normal or otherwise, the cornea has become opaque to a certain extent, but has still a transparent portion left. Behind this transparent bit of cornea exactly, the new pupil must be made. Or, if the cornea be transparent over considerable of its surface, we enlarge or extend the natural pupil in a direction which will render it most serviceable to the patient. Other things being equal, the extension of a _~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~ C 2. fm w., -T; a fX-,,a; ~+/ _ c X" _ _ n _ a _ 3 ~h h. +< e, if ~v| s~ r k _ < NO _~* _ -; _ e 8C,. xwTV _>a - e *.; f i _ + _ a~ i _~t~ 1. _A z * l,* A-Y.*,eFPt Bass~ ~ o'sFW 166 ttl.1 IRS. drawn tihough the wound, around which a loopI of fine silk has previously been placed. 7The portion of iris drawn out is ligatured with the silk, and in the course of a few days sloughs off. A doublei iridodesisis frequently performedl in opposite ditrections \ whiclh gives a- narrow slit for a, pupil like tlat t olf ia cat This is, the operation1 somletitmes do)ic for conical cornea. When the anterior cha.'lmber is vry naT trrow, thle'slender cattaract t-kife otf (refe may be u1sed inlstead of the lance-shaped keratolne, in order to a void the risk otf wounding the capsule of the lens. The openilg is mad(te alongltl tihe ri-m of the anterior ch'lamber, as I inl the flat operation for cataract, oMnly shorter,: Artifieial pupil by.inctsion simply, wifth a: broad needle, such as K:nlt:app' s (ig. t32), tma.y l'e prformed ftor a pupil centirely closed, when tlher is no lens, as after I cataract operation. A.fter the punctureI, ithet fibres ofr tthe iris, if it is tolerably healthy, w\ill retrtacit sufficiently to forlm a I pupil; if not, a. bit; of tthe (ctt redge of tiher 3LV 1 ri-is my le: drtlawn out at the smal at pert.1re Fom. 32. I. in the]n. corna( and excised with the scissors. A much more ditlicult operation, thatt: of excisintt a. trilangular piece of iris with delicate scissors(, is smtilmes resorted to under simil ar i rcumtsta ces. MYDRIASIS. 167 AFTER-TREATMENT IN THESE OPERATIONS may be very simple. A bit of linen is laid over the closed lids, the orbit filled out with a little charpie, or absorbent cotton, and a light bandage applied, and for forty-eight hours aconite may be administered hourly when the patient is awake. It is rarely necessary to resort to the cold compress. MYDRIASIS signifies the condition of the pupil when abnormal dilatation and more or less immobility are present. It is a well-known symptom, when binocular, of grave diseases of the brain. It is generally, however, of much less serious import, and may follow a rheumatic attack from exposure to cold or wet. It follows upon partial or complete paralysis of the third nerve, and is often of syphilitic origin. A very common extra-ocular cause, according to my experience, is irritation of the sympathetic, from disorder of the digestive organs, general neurasthenia, spinal irritation, or, in children, helminthiasis. Monocular, as well as binocular, it is often owing to deep-seated diseases of the eye, which, by diminishing the sensitiveness of the retina, impair the reflex action upon the ciliary nerves which control the pupil. It frequently follows injury of the eye. Sometimes the cause cannot be discovered. I have seen a case of dilatation of one pupil of five years standing, in a woman of forty-five of apparently perfect health, the eyes otherwise normal in all respects. The affection occasionally follows injury of the sphinc 168 THE IRIS. ter of the pupil from pressure of the lens in extraction. A constant subjective symptom is the impairment of vision for near objects. I cannot define any particular plan of treatment. It must vary constantly according to the nature of the exciting cause. The affection is often a concomitant of paralysis or disease of other parts of the eye, and the treatment is spoken of elsewhere. Eserine or pilocarpine applied to the eye is generally of temporary benefit in restoring the size of the pupil, and improving the vision for near objects; the same remedies are reported occasionally to have been of permanent benefit also. ACTION OF ATROPINE AND DUBOISINE. Atropine, to be used in the form of a solution of sulphate of atropile, which is exceedingly soluble in water, acts on the iris probably by paralyzing the circular fibres. The iris is extremely susceptible to its influence, a solution in water of I-o0-o enlarging the pupil, which it reaches by absorption through the cornea, with great certainty in the course of an hour or two. The disadvantage of a weak solution lies in its feebleness in overcoming any adhesions between the iris and capsule of the lens, and also in its uncertainty of effect when the iris is diseased. For the enlargement of the pupil when the iris is healthy, a weak solution, such as a grain to ten or twelve ounces, is preferable, from the fact that its effect passes off in the course of a day or two. A solution of a grain or two to the ounce of water is often desirable on account ACTION OF ATROPINE AND DUBOISINE. 169 of the promptness of its action, a half hour only being required for its full effect. A solution of four grains to the ounce will act still more promptly, and will also paralyze the accommodation more or less completely; the effect of such a solution on the pupil will not pass wholly off for eight or ten days. A solution two or three times this strength may be used in attempting to break up old adhesions between the iris and lens capsule. Very strong solutions, thirty to fifty grains, are not to be commended, lest cerebral symptoms supervene. A long continued use of atropine renders the eye intolerant of it, and in very rare instances it proves too great an irritant to be used at all. Homatropine hydro-bromate acts similarly to atropine on the eye, but more feebly, and its effects pass away in a day or two. It cannot be relied on to perfectly paralyze the accommodation like atropine; still, used repeatedly, in some cases it acts sufficiently forcibly, and is then preferable to atropine as the eyes can be used so quickly afterwards. Gelsemine in the form of a solution of the hvydrochlorate in water is less useful in ophthalmic practice. Used in a solution of about four grains to the ounce of water, it causes a maximum dilatation of the pupil in about an hour, or a little later. For the purpose of ophthalmoscopic examination this alkaloid is, like homatropine, quite suitable, as its effects on the pupil pass off in a day or two, while a mydriasis from atropine may annoy a patient for a week or longer. Gelsemium, used locally, also affects the ocular muscles. Measured by prisms the internal rectus becomes 170 THE IRIS. stronger, the external weaker; the internal gaining more than the external loses. Evidently the termination of the sixth nerve is specially affected. Given internally, it acts on this nerve, and in large doses also upon the third nerve. In poisonous doses externally or internally, it paralyzes the ocular muscles. Duboisine is, owing to its rapid action in enlarging the pupil, often a convenient substitute for atropine. Four grains to the ounce of water in solution will enlarge the pupil ad maximum, in from six to ten minutes. When atropine causes irritation, it is also the best substitute, as its power over the pupil is more than equally great. It also paralyzes the accommodation, like atropine, and its effects pass off more quickly. COCAINE also causes a temporary enlargement of the pupil, and as it leaves the accommodation unaffected, acts quickly, and as its effects on the pupil pass away quickly, it is very suitable for dilating the pupil for ophthalmoscopic examinations. It contracts the superficial blood-vessels of the eye and causes a slight retraction of the eyelids. 1MYOSIS, signifying the abnormal contraction of the pupil, is sometimes seen in iritis, and frequently in disease or injury of the upper part of the spinal cord. It has also been observed in hyperaTsthesia of the retina, and in persons who work at small objects, like watch-makers. Idiopathic myosis is extremely rare. MYOSIS. 171 Eserine in the strength of one-eighth grain to one grain to the ounce of water contracts the pupil, the more quickly, the stronger the solution; but the strong solution is quite irritating to the eye. It will overcome the mydriasis of cocaine, but not of atropine. It causes spasm of accommodation and decreased tension of the globe. Pilocarptne acts on the eye in a manner similar to that of eserine, and as it is less irritating, I use it frequently in preference to the former. It is inferior in myotic power. Miuscarine is reputed to cause an intense spasm of the ciliary muscle, and is also less irritating to the conjunctiva than eserine. Iridodonesis, tremulousness of the iris, is a certain indication that the iris has lost the support of the lens, as after extraction, in dislocation of the lens, or as in hydrophthalmia, when the anterior chamber becomes enlarged. Cysts of the iris may be excised together with that portion of the iris to which they are attached, by the operation of iridectomy. Irideremia, absence of the iris; coloboma, cleft iris; corectopia, an eccentric position of the pupil; and polycoria, more than one pupil, -are congenital anomalies rarely observed. CHAPTER IX. THE CHOROID AND VITREOUS. HYPERBEMIA OF THE CHOROII) is undoubtedli of frequent occurrence, but is very difficult to diagnose with the ophthalmoscope, as the vessels of the choroid are, except in very light-complexioned persons, almost completely hidden by the pigment layer of the retina. Nor unless the iris and ciliary bodies are also congested, does it seem possible to diagnose it without the ophthalmoscope. CHOROIDITIS SIMPLEX, OR DISSEMINATE) CHOROIDITIS, can hlardly be diagnosed with certainty without the aid of the ophthalmoscope, as the otherwise noticeable symptoms are common to other affections. There is usually some dilatation and sluggishness of the pupil, some failure of sight, irregular obscuration of the field of vision, so that perhaps but parts of objects are seen at once, and usually little or no pain. Sometimes the external appearance of the eve is quite normal. The Ophthtalmoscopic signs are general cloudiness of the choroid or vitreous, but oftener we see small yellowwhite patches of lymph, first at the periphery, aftervwards about the macula lutea and optic disc, and later, if atrophy of the choroid occurs, the white sclerotic will 2-( ~ ~ ~ ~ \*- a al *J in. ~~c. M > a li; #tie:::%o S + %e re, l ~ ~f~ w H *I~~ i................~.............................. Y1~~~~~~~~~~~~~ ~ r* ~^ U t ~r Y1iiiiiii I~ ~i~~~~~~~~~~~~~~~~i~ ~~~~~~~~~~~~~~~~~~r r~~ ~~~~~~~~~~~~~~,,,i!?~~,....;c ~* "t-u~~~~~~~ ~ ~~~J1 % c~~~~~~~~~ ~",,?~i~~ 174 THE ClHORO1) AND) VITREOUS. Pt/he prognzosis must of course he gtuarded, owig to t the tendency to complication tand atroplhy of the retina and optic nerve. Sometimes, howeve-r, the exudaltions are absorbed, leaving but faint traces of their existence behind, and sight is tquite restored. ia)rtal chrooditis), a steadily dtcreasing visua:l I owcr in idcerly people witih normal field of visioll points to at circuntlsribed p)atch of choroidal' infilammation bleneathl the macula lutea. 1The ophtlltalluoscope shows a yellowFi'. 36 ish, i: rregtularly sha. ped spot with pigxntent:ed outlines, and there is lno t-ttendellnc towards spreading. There is no dangc r of total blindness. x Figs. 8*6 and 37. Aetanorphopsiia, that is, distortion in the appearance of objects, is observed, and of course ttere is a central scotoma. See page 226. Allied t t h is form of choroiditis is the Am-etropit rettz-ah/aroai{titi described by (Gould. It occurs in A. of Oph,, vol. xix. No. 1, (MCIIt(O )m.t.f'1 SIM1.| IPLEXt. 17T5 younig people, atrl id s (ui to:o eve sta:iai in amnletro-'ii1a, ciefly ht permet iroei astigmatismt.'ihtA ItaLCula r rgionll is slightly pigmented. TIhe' lesion is retinal., T1le treattititult is to cor'red the aiitet ropia bIy prolfperi @lasses, t'ie atte2menate at' Chorloiditis Simplext: mustt II tbe gonv terined to tt great extent by the state: of our patientls hicalth otherwise, tand the catuse of the disease. Fita. 37. T'Iisi is f(requentlv syphilis. General ll it will be found that tie liver, dtilstivt' otrganst, or the uterus aret dtisordetred. All these cirllulltanees will inltlence our tr eatm eunt. A t a ll e vents, the patilent should abstaint fl*1rom> tlhe utse o-f tthlet eyes in readinl or sewtig, and guardl them a(ainst bright light out of doors b wea\ r ing dairk glasses. In old eases of irido-ehoroidithis fth operation oft iri 176 THE CHOROID AND VITREOUS. dectomy will frequently be indicated for the purpose of breaking the adhesions between the lens capsule and iris, as well as for the purpose perhaps of laying a pupil before a transparent portion of the capsule. The operation is, under these circumstances, beset with difficulties from the narrowness of the anterior chamber and the degenerated rotten condition of the iris. If the lens is wounded in the attempt, it must be extracted. SUPPURATIVE CHOROIDITIS, called also panophthalmitis, or ophthalmitis, is a very grave disease and its course often rapid. The eyelids are usually red, swollen, and edematous, the chemosis very great, so that the eye appears swollen. The iris is bulged forward, and discolored; the eyeball sensitive to touch, the tension increased; and we notice, if the pupil is sufficiently clear, a yellow reflex from behind the lens, due to a purulent infiltration of the vitreous. Sometimes the pain in the eye and the region about it is of the most intense nature, at other times less severe. Sight is, of course, rapidly and greatly impaired, and frequently all sensation of light disappears. The causes are suppurative inflammation of the iris and cornea in bad subjects, typhus, typhoid, py.emia, injuries of eye, surgical operations, or sympathetic ophthalmia. Certain cases occurring with exhausting diseases have recently been proved to be due to the presence of streptococci in capillary vessels of the retina (vide Ophthal. Review, Vol. IX., April, 1890). OPHTHALMITIS. 177 The Treatment of Ophthalmitis in the commencement should consist of ice-water compresses and the internal use of aconite. It may be necessary afterwards, if hot fomentations and the administration of the indicated remedies do not relieve the severe pain, to resort to the subcutaneous injection of morphia in the temple, or the paracentesis of the cornea. If the febrile symptoms will permit, the patient should be allowed a most nourishing diet, and perhaps a tolerably free use of stimulants. It is, of course, often impossible to save the sight of the eye, and indeed frequently any part of the eyeball, in these cases, and sometimes life itself is endangered through the extension of the disease to the meninges of the brain. When the disease is foreseen, and before the suppuration has become general, enucleation of the ball is probably the best course to pursue. Recently the operation has been frequently performed, under strict anti-septic precautions during the suppurative stage, and no harm to the brain has ensued. Noyes relates a remarkable recovery under free incisions and antiseptic applications, after enucleation and threatening meningitis. Diseases of Eye, page 501. Metastatic choroiditis sometimes follows a meningitis in young children, and leads to blindness and atrophy of the globe. Serous choroiditis is usually associated with a serous iritis or irido-cyclitis, and would requile similar treatment. See pages 158, 316 12 178 THE CHOROID AND VITREOUS. Tubercular choroiditis, connected with a similar disease of the brain, is a very rare form of disease. Miliarv tuberculosis of the choroid associated with similar infiltrations in other organs, is more frequently seen. The vision is generally normal. Tumors, ossifications, carcinoma, and sarcoma are met with in the choroid occasionally, but they are comparatively rare. HYALITIS, or inflammation of the vitreous humor, though usually an accompaniment of disease of other structures of the eyeball, may possibly occur idiopathically. In simple hyalitis we notice, with the ophthalmoscope, that the whole vitreous is clouded so that the details of the fundus are indistinct, while floating about in it are discovered delicate shreds of various sizes and shapes. Generally with this form of hyalitis there coexists a retinitis, choroiditis, or cyclitis. A.supp',rative hyalitis supervenes upon suppurative iritis or irido-choroiditis, and occurs after cataract operations and injuries of the eye, and is sometimes the beginning of an ophthalmitis which destroys the entire globe. The treatment of hyalitis must have reference to the primary seat of the disease, which is in the choroid or retina. I have never met with it in its idiopathic form. The prognosis is not good. Opacities of the vitreous are frequently due to remains of effusions of blood or lymph, degenerated, fatty, or pigmented cells, membranous debris of varied form and size. These opacities may be seen best with the oph OPACITIES OF THE VITREOUS. 179 thalmoscope in the upright image. Let the patient turn his eve in different directions in quick succession and the opacities will be noticed moving slowly about across the pupillary field. Such opacities must not be confounded with the condition called muse volitantes, usually a subjunctive symptom of less import. Muscle volitantes are either transparent or opaque, and are best seen by looking towards a white surface. They are probably caused in most cases by over-use of the eyes or by impaired general health, and consist of the debris of cells, shreds of tissue or fibre floating about in the vitreous, and slowly changing their position with every movement of the eye. They appear transparent and bead-like, or in other cases shred-like or as dark, queer-shaped bodies. Rest of the eyes should be enjoined, the general health attended to, and, if very troublesome, colored glasses may be worn which will render them less apparent. They are more common in myopic eyes. The Treatment of Opacities of the Vitreous must be directed to the removal of the cause, which will generally be found to be an irido-choroiditis, or choroido-iritis, or some affection of the deeper structures of the fundus. Occasionally fixed opacities of the vitreous have been torn through with a fine needle, and the visual powers of the patient improved by the operation. Synchysis is the name for a fluid condition of the vitreous, in which its gelatinous consistency is lost. It is difficult to diagnose with certainty in all cases. The free movement of opacities presupposes it, and 180 THE CHOROID AND VITREOUS. when vitreous is lost from a wound or during an operation for cataract, we know that its loss is made good by a fluid or serous substance. Sparkling synchysis expresses a state of fluid vitreous holding crystals of cholesterine, which present a very striking and characteristic appearance under the ophthalmoscope. Their origin or mode of production is undetermined. CYSTICERCI IN THE EYE. Von Graefe had in eighty thousand patients eighty cases of cysticerci in the vitreous or retina: three cases in which it was in the anterior chamber; beneath the conjunctiva, five; and in the lens and orbit, one each. The result, when the cysticercus is deep seated, is the loss of the eye from inflammation, and degeneration of the choroid and vitreous. Von Graefe occasionally succeeded in saving the eye through the extraction of the parasite, but the operation is very difficult when the animal is seated behind the lens. Alfred Graefe has operated successfully in twenty cases out of forty-five. The original seat of the cysticercus is usually beneath the retina, where it may be seen with the ophthalmoscope as a grayish-blue vesicle, whence it emerges later into the vitreous. The affection is rare in this country; I have seen but one case in Boston. CHAPTER X. GLAUCOMA. THIS is one of the most dangerous of all the diseases to which the eye is subject, and, without timely surgical interference, generally terminates in blindness, and, later, in complete degeneration of all the tissues of the eye. It is not a new disease, but up to the time of the invention of the ophthalmoscope it was not much understood. No remedies, surgical or other, having proved of much avail, it was quite natural that an almost uniformly fatal disease, of which very little in regard to its nature was known, should receive less attention than others better understood, and which permitted of satisfactory alleviation or cure. In 1854, Ed. von Jaeger, soon followed by Von Graefe, gave accurate descriptions of the morbid changes in the fundus occurring in the course of the affection which drew attention to the disease, the interest in which was widely and quickly spread over Europe when Von Graefe, in 1856, discovered a successful surgical remedy for it in the operation of iridectomy. Perhaps the most convenient and practical way in considering the disease is, to divide it into three forms, -the acute, subacute, and chronic. 182 G. At (JMA. T' HI E IitMO: t O N' SYMPTT t: i'i X' 0 315 -'t() 3IS of actite gltaucottc:m a Pre uisually, ftirst i-t or(er, a il(treased tetion (hardness) of the eyeball. This is ito te dctclied(l b thI lou}d a tS.ur'eviontslyv (dcsert(iid.' lIt sltbjtetitvde. sy')toni o) f tlness aid swelling, so oftel felt in eonnjtltivitis, i tiriti, or sclt.riteis, is not to be mistiken tfo) illncreased tensionII of fle bal t whi h indllicat;:et( es'11w approach{)tlI of atn (acute tt attalck of glaftucon)t. With this te-1:.sion.: co(m.W its itst lre. tit l:ateR frutits, pe ri(odii: dimne i ss of visiol stuclh a s onle 1may pfl'ro(uco by prjessurt e of the finger ttupontl th:e ntormalt eye, lasting for' a few mometrnts 0or lours, and a rlapid development: of iiany Il,'vioutslxy exist'ing presb'tyolia. Thle pupfil is somewha}t, blut not; greatly, dilatedt; etand as a seiquel of thtis, the pati ent noticet-s a h4 lo 01o rlainlbow ar.1ound the flanme of,a crandleI. 1he ri ng around the light is at its outter side rled its in:mer, } ttIish-gtreen. iTh mat e m) or 1' less cilibarvy neutlralgliat over the eye, in. tthe forlehetad, temple, and fatce; but in. Lmy cx pe riic:i'e, ti s sy-lmpt(oln at th is time is lnot commru. T1 above:t lrt onitor symnl)ptlom:s 1ar those obstervabtle withoutl the use of t-he opltthalm ntos(;f)ope:', and may oc'. cur merely at intervals of months; but, graduallg y'the intervals sh orten, and only weeks or dIavs: is tervene )bet.wetn tilhe reculrretnce olf the synmptomst, and the next stage of t fhe (disease, confirmed glatucomt.,ti mai t:t)e lo()oked for. eI rc:'eaft:er, tho tgh t here are to be pelrhaps pe riodic exatert)bationrs, ithere may n1o.t be., ) in t:h pmn]:l()itor-:y stage, any pe':tiect itermi s sions.. The pa:tient m ay be 8suddenl v seized wifth a terriile neu'algia ove'r the Ti'J Pit MONI' t)iY SYMPT )M$ 183. eye, in the forihclead, templell,, lace, d(owl tmhel side of th se nose, with severe constitutional S\'nptonls, }tigh fever, ailsea, aind even vomiting; s, that the: affiection may be mtistatken for severe hiilious or ti)hoid fever. In. one catse, I ftoutnd the disease h}ad Ibeen diatgnosed as an. infitlann atit)o a ffeetio) 0)f tie lra in. An exa(ni na-:ion of the eye, ho.wevert, wvill torrtee t}he d.tliagn.osi s. l'Te lids will t e ft oni:td pit tidy nttd sxvwfolle, ath.e (oinjlt.it:tiva itjetccid, tIlere is ehemnosiis,.1,0orce oP, less cl t di ness of thle aqueous liilltl'r, tist.eolorat ion ( of) the iris whl'ii):ppe)ars }tit':ged f(:,r-war'd ailn(.)ist: agtain(st tthe corne:?a, dilaitaltim ) of the plp il, t:)an dec{ided t.enlsion of thOe evbt all. Viton is always g'reatly inpaired. /I hl:ave never known it- wltl l ost: at: this stagc, al though l t:his lias not hilrtqi'f tei'ly lappenlted..P atii.nts will gent:rally see a hanld held very near ihte I eye, or be atitle t:1) tdistIingulislt tthe lar1 fge gilt. lettetrs onl the 1bac:lk oft a book.'l'he]y are also disposed to( spe-ak of sudden flashes of light btelfore the eyes, and p)terhaps o(i:t ter slct rt ral pthe. - tnontena. {Thest, wit It sotunt ph:otioplhoia:4 and lac1 hrytmaion), alnid more or (less a ti'steltsia. (of the cornea are the ltmar.kedt syilptomnls t observ'ved in thle tegintnirn: (o-f (1con1 irmI d gI l a u1o.ma As tle acute. at tah(ck ptasses a way, the sight will gfrow tbctt cr, and perhapts very much b}elt: tr, }hut'the atppearat.e1t olf tie eye with tta mll:odific hatioln'of' the severe in(:Iantlmait(ry astpectI remainis, Ti4' a'I,(ttt:a:ks r'ecur, the, sig ting lt i tla fr tet'.eacht in a. worse condit-ion.'(lte:tensi.on ofT the tvte increases, teli iris shlriv'els, the a:nte.ri:o chamnT:ril)' becomes still narirower, t-li: stlb-cinjulictival veins appear l urlbid td t ort uous, the ield of vision 184 GIAUCOMA. becomes greatly contracted, thl senxsibility of lte cornea diminished, the so-called green reflex is marked. I say so-called green reflex, because the reflex, to my eye, is more slate-colored. No doubt); it is sometimsl giee-nishe, but if on1 looks for a decided green rcflex, sullh as is frequently noticed in the eye of a cat, hle will b1 diisaptpointed. The diminished sensibiSlitv of tile cornea( may )be detcerined by toulchingt' it: with a hbit of paper twisted to a ointt., TIi1 0t) t)' i -TiALMOSCOP10 I(:W.? S~ YMPTOMS I'( in the premonitlor\' st:ag are witoll absent,, or, at most, frequncciitly of merely negative valIlc, from cloud i ness )of the ct'orneatt. In the sta(g of contir>t nled glauctatl ~:there icay.' be m (ore or( less e(xcavat:ion of the optic distc, dilati(a, iand tit rgefmscenct(t at a t(ort)'itsity vf t;the ret iltal veins, antdt vetnous puls atit n. At a later stage of the disease we imayt find tlie artt:eies thin atld pale(, arttrial tpu'lsat iion, llhmorrthavge int(o a.d t'encral cloudiness ofi the vii lre ous,. Thl la rge l e exca vat i(on of the optic nerve ldiff ers lfromn t. e physiotlogical an d a.al l urot ic excava(tiollns, in size, depthl, and in the ai}b rupt)t ess of its cttge, in co)nseqt::ici tlte tf v)twhich the ref tinal a vessels, in curlitng.t',over ttle tmagin at the:)order of he l1 di sc, are much dtisplacted. (ioiattare l' igs. 88 and 39, on the next )pag,'( he:althy opftic discs, with thlose of Figs, 40 and 41,.IFt'tiieueintly, however, the imttedia in glaucomna are so t.'rbid thflat nothing'whatever elcan I)e seen with the ophtht:almo()sope. Fortu nately, whlen tlhis is tfhe case, the o;ther. symlptomtt s are so ctha ractristic that no etrror in diagno". sis need occur. The field of vision is usually contracted ~^lb................ S, =d ^^^-t ^J, I -- t 5' ": in t -..==_============.^.......-..' 1':'i Z::Ia':':"".. -- ^ ^ 31 ^~3 ^ ^ o ^^ -"* "* ~%C~* C~C~j~;r I:I4/1< C Gr, ~ ~ ~ ~ / -, S - o.-o.f~vt.'< -J ~'": tI ~c~I~~~~i~~jS ~~~U ~~~4 ~~ U:~ rs~;""''~~~~:''' ~~Z 18~ GLAUCOM A. tag'e of tlie acute formt wlheI the exaeerbations lhavin di lniish ed swomewlhat il iiltensit-i, the ilalammationt is Fis. 40. fixed and gradually l rogressive, and the sight gradually failing. (.It oni f on-ifammat:(.r/ / /laucoma, asom.etit es c.alIled glaucoma. simplex, is very ilnsildious in its courxse, and of I(I C III I. FtI-. 41. ralre: (.cc l'rre'llt'e x'}:)1l':re'd1 to 10t:llerl' fom o: f the affietioll, Itt has not; very unfrelque.nt ly haltppened thatt pat-ients Ihave been(.tii nitawarvIe of thll existenl(e of this disease in onle eye, the other )("eilnlg well, until it a1ts tompi)letely ~~~ -W - - I - -,,,,.A, i -/ -I I'd' i* or I ok - ~ am, Crm Be X, a_ ok,* a ~~ a _~~ He *i rY v. ~rr- r r ~trT5 - e ^ X,- Cr *X _ t_ _ c: Em, >; X _. t _ _ _ C - >e C. ) _ **Ca ~ ~~ ~ ~ ~ ~ ~ ~ ~ ~~~~~~~~~~~~~~~~~~ Crp,~-c -r a- CC - ~c~~~~ ~~*~~~~ C* iv ru.rz~~CC -- - ~~,~r 188 GLAUCOMA., lttaucomSfilmnanstttm s l( is thel name formnerly given by \Von Gmr ef: to a very 1rare form of glaucoma:, the most datngerous of all, il which the rdiesses progrcsses with such fearful rapidity that the sight of a, p)reviously sountd eCye mayC be wholly destroyed in a~ few hours, or even, it is statCd, in half an hotur. Absol-ute gltaulcoma, as tthe di tseiase is termed when all perception of light has disap)pearctd, is frequently distinguisthed at at glance by a pale-greenisl opacity of the lens. A.t this stage of the affection the patient may suftter from severe att:acks of ciliary neulrarlgia. Ltater, the iris })comt:oes completely atrophied, tilhe cornea opaque tt and softe( ed, the choroid and retina degencraite(i, antld ttthemor~lthagic efftsiont t:akes place within t:he fllutdus, stalphv)lt oma of it'he sclerotic, anld frequently inlanmlatlion and att':rophy iof the gl)obe:( follow. THEX CA.Utl' OF (0.FGLAUC(OMAI. is not yet:ftlly dlenost rated. l.There tis, first, anu affection of the iris, cilia1ry bodytN, antd the clhoroid; tthen, an increase of the. humort s of the ee, v an ilnreas(e tension andt xca( vat:i.(on of the optic tlnerve; then, the cornea, sleWrotic, tand retina become invol.ved. The space of Ponta. tna is obliteratetd and there are adthesions between the perilphery of the iris and the corneta. Comrn pare Figs. 43, 44, aft:er Nettleship. the fact that the sclerotic in this disease is found rigid antld unyielding is sutpplosed to be of importance; for the disease attacks generally o nly those of an age above thirty-flve or forty, itn whom the sclerotic coat has already attained a tfirness and rigid ity unknown in youth. An interesting THtiE CAUSE OF GLAUCOMIA. 189 and perhaps rational theory is that which attributes the hyper-sccretion of the fluids of the eye to some abnormal irritation of the ervces controlling these secreFi. 4,3..~etion through the ciliary regio n in a healthy human eye. Co, Cornea; Scl. Scle. rotic; (1. At Cliary Muscle; C( P. two i lary proc<-cses one larger than the othet;.r, Iris; t, tie nmarginal part of the erystallinte lenss, angle of anterior chamber; 4, mem* brane of et:scemnet, which tease.s (as sueh) lwfo e re aching the angle ct. The doteted line shows tVhe course probably taken by Ithid from the auterior part of the vitre. ots into tthe posterior aqueous clamhcr, whe r e i i a gmenited by aineous htinor seAreted by the anterior imart of the euliry pr roce, the nce t hrough the pupilt (not shown) into the anterior aquejous chamber t tthe angle.tt. Suspensory ligament of leins not shown. x 10. ti.ms, this itrritationl beini't'refltex frotm tie sympnathetic...Thias hypot hesis mak L( l. th t increase of fluids thfl essenet of the. disease, and the lc(lMsequent t:ensio of t'he globe *::: - - 0 f...-. -...:.:..::.,,?,?o.1X.t. F.m. 14. Cii i fa r,:egion in a c ase of clhonic gilaucoma of thre ye ars' standing. Notice the ah.esion of irs intd cornlea at thte ang*tl of the anterfor eitan er.' the caus e o f the ni a. ila atorv syml}:)tois, l.The iuterir' tissues of I1he, e i become i rr titate d anlId inflam ed from thils mee, l ical pr.esatlure, and lfi ally degenerate 1.) 90 G(LA UCOl MA. ftrorl.tis'ets a d lackl t oi. nutt; t:iot n, Nat.aut son records t; \g t i l -f3 tl t:E~ t ut ct 8t~f (A i c II C o tI 8 I f )N\ Tll II S.l1i t Cv t 1:t1 I tIwenty-eight cases of glaucoia llowing senile cataract ext m'rct ionl r/eai tue.- it..t is dou:tli lt it' any m asurt s ottit r ttha slurgical are of Ip:o sitivc v alu c inl tihe tttI tt itcitt t f gla co ailnt but whetn wi. re l. ct theatlt itt a g'reat mlaj r ity ofl ceases thcre ole.x i st e.lio.ls c nstiit-utio 1al iiist tlances,. sutch ast gtolt. rIeoltt'ltI:nat:istt, u ttlltiot t' nal'or (the. r (t iscase' of ( til dli.gevcst ive orga t s, lienIm rrlitioids,.......... and, iln femaltt es, that th.. afft-enct. io 15 apt tlo occ rl' at thOt, pe.riotdi of c1 essalt:i (.nt t mllettsl. r -ttai on, it sc(len.s a'l ostI il mt oss.i ble th.i avoid 50 4\t41-:f.. iIttIa 1czlttti lt i. (.) "it fftrl- X ti'le clile ti sio tt I {s-}i a t' tiItthe affectt iont is oiftlen pri ttnait l ext r a-cait: t I a ir tlta sfrlt. at thie an {lit st st tae, at t artefli, intellig enti, me:d ica I I reatmln et, cmbliiintaed v it strict tyt ien ic regC lati t i si, i tl IIt hi l it roxVe ci lrativ t i in ce l s rt in\t cas es. In e t. imst 1ih ti tlt: > e effec. ti t (if tied:t ii t i(t' i t it oweve, i wett st:s t t.tovirlt c k thl e cir, ei., sta c tc IIt tItat aln t acuttec attacklt i th: e Car tliest stiage naiax re t:eate y 1 itipass fl(t: lteaving I-'tfi sight t ntlt l pair, t.'t' N dt bit.)' r I me{:t lll dies t mtl: friove{ secrviieeafile in rcliie vilnt or si ot'enI ingti l'he iuf.lrati)ot of at n atttifackf ttit to he cit. rativ e, thex\y mlst prIeveit. t:It its re rrt. ( t (., Ic.I just as the ofle t attio ot1 i trid I t (m w he' st(icci ssf'ttl'{.l itprevets i.ts rec.rence.1't('.t tn er t. o }ft' ren.ldics'lis tl"e t Iest poissibll ct han(ce of pr't vin'i.tg of pe} rln'anel-it'lenef it 1.:, t:lti slo, Iltt {,' t t mi isi. t. ctre a lst du1 crini t the: pi ioi t (otf iit ttcrnissiotn, W\\ (}lt c+ tt {V tI b sureIt that i he t''recatm:ien tt is prox vintl ofi' rtea l service wht en we tfi lI t:hat it'reduces thie lardness /: ft? q/oh. e. ff atever ill rweiduce t fll tensio of the I'I ii a laia' tiill THE CAUSE OF GLAUCOMA. 191 cure or at least relieve it. It is said that a number of cases have been thus benefited, through relief of tension, by the use of eserine as a collyrium. Eserine should certainly be tried in the early stage of the disease, although I should myself never postpone an operation for this purpose, if it were clearly indicated. Some surgeons prefer pilocarpine to eserine, in glaucoma. The habits of our patients should be scrupulously looked after. Of course a moderate use only of the eyes should be allowed, — bright lights and crowded places are to be avoided; sunlight to be modified and deprived of its piercing yellow rays by the use of colored glasses when in the open air, especially to be used to protect the eyes from the sunlight upon the snow, white sand, or water. In addition to this, all habits which affect the general health unfavorably, — such as the excessive use of tobacco, alcohol, or other stimulants, - all dissipations and exhaustive labor, mental or physical, should be strictly prohibited under penalty of loss of sight. The diet should be attended to, any idiosyncrasies of the patient in this respect ferreted out, and indigestible articles forbidden. The diet, however, should be good and nutritious, and, particularly in elderly persons, the confirmed habit of indulgence in stimulants like tobacco, alcohol, tea, and coffee should not be interfered with, unless it be necessary to substitute moderation for excess. Internal medical treatment cannot be relied on exclusively in the treatment of glaucoma. Doubtless it may be of more or less service in many rheumatic or 192 GOAtJCOMA. arthritic patients and in cases complicated by hepatic, hemorrhoidal, or uterine and other affections. Such complications will suggest the remedies better thanl thev can b:e suggested herle in a general way when indicated by symptoms apparently only remotely conlected with the disease of the eye. A serious obstacle to the success of any and all treatment lies in the fact thpat patients rarely consult a. p)hysician until the dtisease is confirml ed, and too great tissuechanl,:,ges tha've occturledt. Matny p)atients sent to mle are suchl as have been tconmptletey Ib li nd for moInth, and sometimes years. In c'ases of com.plete bli)tdness, an o)peratim is isindicated simplyt for the relief of a tormelntlingl nutralst ia overt the e. No restoration of sight, is possible. (Only now and then dtoes a c:ase prtsentl itself at thie moist favonrable time for, a: sulfccessflll operation. If we - inqui re into the cautset of the delay, we lind th"t:u no attentlion what-ever was paid to t e the (arly symiptoms; t-} attack tlwas veg rl cd ts ra het.adach -te, 3rheumat:is from a ctold, a ucral(gia in the head, or s0ome ailmentlt not immcediately conncti ed with t he eves, and no advice Ias sou"I'0htfl untiil?.... aft.er. the advent of a terrible aitack of acutec intfammat iolt, or' tint il the siight wias found p1)tereopl( c ant iltn ctases whe\t.r the e'xctitilng cause canll te removed.(1 _- nCt g p*,~ A o Of,.! w "~~~~~~~~V - 4:l Vtosi..,,. -4~ ~ ~~~~H -tn- - - - z. X _:FI - _t Ii' ^eso - ~ i 200 Ti HE RIETINA AND OPTIC NERVE. Iitlt work t y arltttiicial la Iigt,t altlt a radtlical cltualtg of occupat tion will tdo mucI to pro mote a cur. Very oft rt there wvill be found diorder of some of the abl domtina organIts 1as a a4lttieC.'fthe judicious trcat.mcntl: tI t any disorder of the. gciteral svs temt l mayl a afct a cure o0 the eves. Cto'tor Id I lastes arU adv lisitble for' out-of — dtoolr tuse, if tihe pltot:oplhobt(i is considrtwablo. Wlhen the afflection is severet com:plete Irest: of the eyes s hould be enjoined. RVI4TI NITIS. 1n the serous ftrm o r'etiuitis we nottice, with tite oph"thahnoscopec getnerallyv a veiled or0 hazy appearanc of the retina, less mtark.ed at theli macalt a liutea wther the inormal tlemblrant c is always of dimlnin isled thiclmknelss, aidt llmoe decided aboutt thie (optic dis(c, whlichl is somewhat svwollen from odm ttl w ia ts out t is tlinl rathe t ndisti nct,.'The arteries areic ntormlal, but tlhe veins appet:a dark and tortluos. Externally, the eye looks well. Perhaps the pupil may ibe slightly dilated and sluggish; but, in m1y exper.ience, thiis is not usually t.he case. Nor atrc th cre any of those symptomns ofi itrritatbility of the eye which. a re so often and erroneou sly slupptosed to exist: in retinitis, ".. suchl as phlotoptmlo)ia, paitit. latchrymation, and the phtcin(t(me:nat: wh ich: tatccompat nyt retinal h vpe, r st chsia..i causes ofl tItis affection do not differ nmaterlia lly firom1. those mcnit ioned u ndcmr lvperaemiia of the Reti n, just described, andt the -i'catnmt ent must. be similar in clharactor, ut of course more prolong'ed, aund cannot, in many cases, tresult as successfi lly. Our p1rotgtlosis t X k oss ea~~~~~ttt.Se }}l~~~~ttl~~~t ttl~~l(>"t/4 Sl1( 9tt}]~~~~~17(t}TI T'liN IN n Ji'ri.s,. 2()01 shotld bie 1moil gluardedt; ifo.l from thle beghoinlllni tihe sig lt s is mowrve i -mpai.ted., lThe veil or (cloud g{rows thiickerl mldil frequen.tly the patient'l is ahlm.ost totally tlidid. UI'requentily, if the 4lisease colltilmes many wtOekFS, atrophyot't f lthe retina may e.nsu', anli the sight be jp.erman'ently destrtoyed( Thlt ev yes shoul d always be protiectetd by, dalrk glasses, and no tse of theml whatever for tlear objeclts 1be t)( pltlnitted, i. reti-nitis elxudaitw,(t, the't dee "per-sfeated ort1 parenel./-" mt.osos,/brt fr1 q tit itis, thle ophthatllmt ostopwie appearactttecs,of the eye are nuhtllci it(ore sltriking. The optic disc is io.dd'ttishl- grattv, ats.od its (outline intitisnct and l. irregtla'r, so dthat.it its allttost intpossible to 1find thte.' line of del-marc.ation bet we en it and the retina..'he ar tettris are. Imore or. less diminiished inj si ze, iand the veins swollenl and tortuos, a 1111d hil dden here anid there n xy t e It si. v sexdat t}ionts tof a whitish or gravyis]t: eo.lol r anid blood ext ravasat ionsl are seen in variouts,partt s o)f the rettina.'lThe albove( is an opdhthal -nmoseopit ic tlt're of a pathtlog(i(ail coin(li:tion in wlhi't tl iite flan- tvatorv eovir i i(nito of the rt.eiti a has ptrodulcedti hyIve:-trrop xhysta sis, tprol i fl:erat:iont of ce(lls, ctollod or fiattly (deg((tenratt:ion, alt(. sc(.'ll(erosis of cot(rsct(. tthe olphthat1lm.) os l wNill n Iot a tffords so cotm)p)let:c a pictIul.re as tt i(e aI.ove\ iIl t all ases oIf t( he kilnd, butt I hav:e obt(serv.e., on more than (:n oc(asimo, lapt.(.eaancest: al..Iostf e xacItly otrrespo( iiig t-on tho) s( deseriled. liv.en in c(ases n.ea(tr.ly like. tlt. above, t'he blood st'asis is sonm)ietilimes re( iev(lved, thoe exdatl, ionas an1d ext-ra.'vasat. ions a)bsoi)r:edl, and the ppatientt mtay rega ai eoIn sideI..rable. vision to ret(.ain i tpe anently. T'ilis, howelver., is )by n(o lmeans tlhe tusual etourse. It 1moreo frequ ent,.ly entlds in. at'.ro.plly'of the 202 TIle' RETINA AND O0,If'C N^1EV.E. retina and optic nerve. Vision durintg the progress of the aifect.ioln is often tolerable until the region of the nmaculat luteca is inlvaded. Aieropsia is often noticed,~.... thatt is, all objects appear sma-ller t t han ty really are. If you ask the patient to draw a given. circle, he invar tiably tdraws it smaller than the reality. Thi t is the result of at de(ra:Itlngclxmelt in the position of the percipient element: s of thel retilna.'When anl exudattion sepa-rates these elements so that there are fewer of lthem iln a given space, objects appear smaller; on the othelr land when an atrophy leads to greater approximation of these elements so that there is an increased nu.mber wit-hin a giventl area, we have an enlarged image of objects or macropsia. The (,atuse^ and'Teatmentt. The cause is f:requently a neglcted hyplcr.emic coldition of tthe rttinatt ad optic nerve, disease of the heartt, of Ithe al)bdlominal vi scera, Ipr egnancy, Bright's disease, diabetes, sSyltilis, or cerebral afifections. T'he t:realtment shoul} d be di r ccted to the rmoval of t he cause, w}hen t:I}is cian bte ascertfai neit. \' Whie of syphilitic origint' tlt tr1'eatt:ment; will t.e more1 apt; to result favorablvl thanl i cerIcebral or Bright1t' s dis;ease..erlcry sfhoutld, I tIl1in'k, te relicd ot t tIll. t} to t et: the retin-ttal indicati ils in t')is formi if the affectJon, and* arsom mit and zine for t l t}he nphriti: ic variety, tisitng suchl oit her rem.:'edics te. lmpora l ril as the st:ate of t,(he patient's heatlth or atny stpeiatl sympvltoims may reqtuilre. See ha XX I.!'ygiemi elt les shotl.d receivet tlhe greatest attent:ittl, tandt thte eyes mt.tf rtatwat be protectedf /' iom bright litiht, BRIG:T'S DISEASE, 203 by the ltec of colored spectacles. With the isest treatmecnt iln evcery respect, thel result will often-. ) prove ntlsatisfactory. XBIt1IHT'fS D)ISEAS8;, OtR RETINITIS AIBUIUttNtIJtCA.'l'h ot)htlialIoscopic appearancc of the eyes in tBriglht's (lisease dotes not diitflr ery mfluCti h'omt that ltready | described, except at a a later stage of the afftec. tion, when we slometils find aroiund the otptic disc a broad, whie ring, and in f te.region of the macula lIte:(sai aI mtll hsteltated whit:e spots, which are later l'o. 48.,erg:t in t:e geneal x dationt. Figt. 48, af(ter Vo a.eger, c rpese nis nea. i,y such a pic (tire as see n wit -1 the ) pht(ha: 1 tn oscp ( al( ) Thi pathohgical /chiaqes ar ri ncilealy tht serouis n filtf rat:i(. of)l ol nervte and treti4na. -t.he f\attv de(ttcteral:ion maI-t1king the white patepcl-tcs, }Ipir-,itrp()lhi(ed and 1cleros(:d nerve fib'es, g:ivinlng rise s t:o a str'ia ttted ap:tlpear.ance 2, 3 f': 5' - z V',_ -n - - _t _-::- r;,z g g -.. -J kl yJ <- - r =-| $ 1t X - -* -- 5 - * _~~~~~~~~~~~~~~~~~~~~~4 r 4e ~>i0W,>z ~-r z *~,. y L 3o e ~o o ~If,~-~~ ~ ~~~~~~~~~~~~~ -i Cec: XB ".lr: c~~ "' ~*#- - - C\'.r' V* Vii -~ * 71~~c fSYPHIL)IT IC Rt f.INI.I.'205i qltently thilatti failing sight, w\ith the conse cient opltt'lt.m)oscopic sexamtiintion lf thei ftunu of thie eyxe, as led -to the detecttion f ltise ase of thte kidney, c(ntfirined 1)n later microscopical exannination of tI he urine., As a rule, nej)bllritic retiniti does not lead tott. c )plete loss of si'ght; but normal vision, ini easttes olt:tan setvent.ity, is not altwayvs regained. Tlhe amont of v'ision rettained will ti-ally he: detetrmilnd by tlhe exte(nt of disea"se of thle nerv-tt s truct:ttre o4f thle retinl. 1If' this has been great, it may lead to at ropIhyv and b indnless.'The prog-' Inosis is, o.f coutset, most fatorI(able ill albumllinu'ia1 after fevers t o in pr eg nane t. The tr i'tcme nt. as far as the eye is conce'rned will be merely hygi.e.nic, and itmedication must bIe directed to the curle of the primarmy se-at of the disease,.......... tie kidney, Y i I lITI( t ETI N OC 0tr Cr! Oit 1 ( I)O-.. t, I 0INI TIS, dtloes (not pi.reselt so chlaraeteristi c a pict ure for tThe oplhthaitlos:.ope, an)d th) e hist'ory oi the ease with the 1ttonstit i uttioii sytil ptlomns sometin' es tretlire to be conisulted before the diagnosis is rendered ceirtain. The app'earan' e of tit futl(tdus is st.riated, and similIta t'o thatl in retdiitis albuminurii aitl i, buit not so well i mntked. Thle stellated s)pots in lthe 1'1egio of the ma-cu11a lutetttl appeat' a{ndl disappelar rapidly, and the vision ilmprtoves and r et roxgrades corr'esp)(ond igly. li:Xtraasations of btlood are not usu'ally not iced. T'/w pattl /oqical eha tnges tare sei'01us infillft at:ion of thle retl' i iniatflmn ation. at dlegeneration of the choroid, Ilitit fortunately lI'he nerveouos struct4tlure of the retina is less apt:; to tibe impaired, and t11ou prognosis is; therefore favort'ble, and espec ially so 206 TIIE RETINA AND) OPIIC NERVt'.Y, if th]c disease comes early untder ltreatmentnt. The disease is usually coincidentt with the const8itutional synlptomls of secondary syphilis, and the treat:lnent muust hb directed to t-h removal of the const-iltitution'at alft'ction. The retinitis pog'rsses veCry slowly, and the )patient is often troutbled by rela1pses. Miterop)sia and niarklledt night blindness are observed, and lait-er a. d ni. shed field of vision. The clhoroid is uall isnvolved, and the trea treat lt refcom- mended for (lhoroid iis wsill genetrally be applicable in this formn of retIinit is. iN RETi INTIS A POP iLECTCA OR il HEMORI t[AG (CA thleret is great tentd nct to extlt ravasat:ions of 1) lood winich are somet:i4me:s so extensive as to Jide l)ar tiallyv the vessels of the retina, and t:lhe infiltrations at' 8slighter. and se'rolus ill character'.. Th'e siglht is not so 11mucht imlp'aired as tlle op)hthal'l oseo]:i(' a:t')p rant e ofl the evye wtould indicate, unless tthe helorrhagl e is sitiuated about the yellow st'po. The diseaset shows g.reatt.endeltcy to re lapses, 1and if i hemorr es recur oft en and are at all extensive, our progno.sis is not so favorable as otherwise. A.l.pplexy of the retilna is caused by disturbances ol:l t|he genel-ral circulat ion, frequent ly tdue to tunlmtors within the orbit or cranium, or to thrtombosis of the centrtal artTer of the retinat. H.)Cpertrophy of the left ventricle, or diesease of the aorttic valves, is not unusual in t.such lesions. It w;'ould bt e very difficultt to state tihe prectise t reatment to ha t)e adopt)cd ti these cases. Tlhe general htealth shoultd be tde de as perfelct as possible, and the patient should, of course, be scrupulously correct and regcular in his lhab.its. F'urther. RETINPITS PIGMEtNT(OSA. 207 than this, the general aspect of each case must determine thet course to be pursued il reward to mediicine, diet, changet of ai, climate, and thle likec. 1 1ETT1 N I' PIGM'NTOSA, NIOGT BLIrN)N iNES TW 1fIll Itl.T BLIN)N E-SS, NYCi1t.ALOPIA, as its names indicate, i. s anL intlammatiol of the retina cl ract ri ed chiieft by great pigment ationt. The ophtlhalttlnoscoie! rXeveatIls tihe retinta cvered by lahirge line:.arl or reticulated irregular platches of pigmeint, more at the peri.phery of the tun't s wIhere. the., deposit (:cointlnces first. iattetr, tlhere is pallo(r oft the ol)tiic disc, diiniittttioun tf. thte retinal vestsels, andt ftlrq.uent;ly postetritor poltar catairat:. It usualtl a ft'ects both e~yes. Tilh stik styri in shmbjctive Symlptomi ill thi altfect.in is nigi'ht bliiidit ess. This is thetf restlt of a t torpid cottnditioln of tthe r(et ina, prod')ced I)v tlhe i ns'ltf'icien.4t suppll)'ly of 1\4 l'X(1 thllr'ot11tt 11th,111 rr1 ed v e sseS il olLset-ItletwL}.)* whsi- cht the retit.'a rqirt: s a b}rig lit lig rnghtt tio re tcciv( y l tile inprev nssion' of oidets. T'll. is oiseat.s:, must no(t-:- }he cvon- i fo-nded witht a t i ona l:ttl t i ree ot,ltoni o te.ioi disorder of 1 thet immnt.la called h i a e ttti pigosa'flhe ltak part represents that part of hemeratloi'ia, or nl ig.it blind- til fiehld in the t-ight eye whicth he..t' tltes', imn'etolled(t mtiet Aim- i:,nl st lyvopia. The field of visiont is oft(eii: vervy 1nui.h.] dimitlishtd iln extent, s(o tltat; WhiT le ill direct lilne (:ll' may 208 T'l:l Im R'l:ET'INA AND) ()}rTC N010 VEI st:ill read flite )rint, all around lmay be involved in darkness. In such event; it may be ditficult for a patient.1 to find his w'ay about'. See Fig. 50f. The diisease is getiterally c on1geaitalt, tor hred.titar, and sloonerf or later leatds to l induness. l xc pt ionaltIlt, however, at certain par; tt of the sight is retai ned. I have had a tase olf this disease under observation for t we.nty vyear's. The man reads coarse tvp, ats retadily as he did twelve yeiarns ago. A pplarently the disease does not pr'ogr'ess tis intstttl'* it"e.'It often o lus i'n m ariatges of c{on.sanguinity anid with d(teaf-t-ttutism. Ft'teatmienti can only oi e l pali ati ve, but th is imay posi' l y po stpone iblindness for years. Thle patient':ls general hedalth should beL kept; in good condit ion, and above. a1l, the,,eves should be spared fatiiguing ocenpations, and gularded from bright li]ghtt and:heat. There is somtetilmes a,physiologic:al pigmentation of the retina Imank ing an oplt-hah:tos)opi (i }picture not ulnlike the disease in que.stion. D) ET'ACI MENT OF T i: XR li'TNA is occasionSled by serous1. effusion:1betiween it tand the c:'horoid. I lt oS tfreqt entl l occutrs i th t s ill e lower ttalf (of the fundils, and commentces at t ei petriplhety. With the ophthalmosctopo we 1mu[st8 look for it first by di'eet e:. tminattt io:. The light need not be very s(trog. Not:ice that th e brighti red of the fundal ls is only seen at the upper part of the pupil; all below is dark; or pe'rhaps y'ou catchl tle illuminate.d part of the pupil only after directin[g the patient. to ttrn tllis eve in differentt directions. T)o not, approacht the eye too nearly, 1)ETACHt M)4ENT OF TTIE REtITINA. 209 and you will see by carefully regarding the unilunmilmated part- of the pupil, and apparently almost il contact with)t it, at grayislh-blue cloud which undulates with every movement of the eye. Fig. 51., after Von Jaeger, represents this condition as seen with the ophFxo. 61. FTw. 62 tha1moscope, and FiPig. 52, from Nettleship, shows a sectional view of it.. For lack of the siplle precaution of using the qpright, itmage, and regtarding thie eye from the distance of twelve or fifteen inches at first, I hatve known aln excellent ophtlalmoscopist to overlook a la.rg'e detachment of the retina. Once havting. made the di0agnosis), we:may examine the detailss wtithl either the direct or reversed image. We fin d thed floating opacity or retinal cloud crossed by dark, shrivelled, crooked vessels. Slightt degrees of detachtmentt of the retina: are mulch more difficult to diagnose,..l'his is somletimes best accomplished by begpinninig with a ret;inlal vessel at the opt:ic disc, and following4 it; t:owardst the tperiphery, whre e e nmay detect at chitange to at darker color, and a tortuousntess i its coutrse; and we make out at the same timte a slight fold in the retina., Vision is, as a matter of course, very much impaired. 14 210 ) THE H ETI.N ANDtlt (.r,'TiC NEf iE. Th'at t)orttion of th. re tilat sep)artated ifrom the ehor oid by serous effusion no lonlger per.tiforms its functtionl; but the pairt which maintltaii its elonneltioii with the, thoroid:performits its futtll:t:iot' as usual. ttln(e it hap"i1)ens ttha.t lte tlp)te. r tpalrt of the i. eld of vision is entirely obscuredt, or, if tih detachment t }appen to }ltave occurred in tte upper part' of the lunduhs, i the oburtm'it(y is.in the lower p'art of the vis ual field. tl: paired vision is first noti:ced!bt tle pati ett as a 4delicate cloud with ilitstinlet wavy outl:tline, ati that point in the field of visio:nl co rreslf:pondiilt exacstly t t the situtlation of the effusion beneatht tthe retina in tihe fundt1us..ilinlear tob:e(.cts apptear wa\t v anid brot ken, due, plrobablvy, to the disttrbed (collct-1t ion f tth retiintt at thte (edtge of tth dehitaohmtt: ent. lThere is oftt:enl xi iht blindn.ss and sollmetiees ta tendencv to cotnftus te the colors!blue tad green. T}he cause of the diseaseit is sonetiles di-iftcult to: determine. It is frequ(ent1 v o(0:1casioned by ai blow on t,:he eve., In a pattien t ot mine, duringi tle p8ast year, it could be t ra:cedtl directi (.v to a fall a few months )revtions. It itav be due tto hem (lorrhage in disease of f.the choroid or retina. T'Ihet co(:mnmonoest cause is, perhfaps, a shrlinking of thet vitrteotus, whil, (rag'tging on the rftinla, causes a riupt)irt', t thelhus ptermit:ting tlh flulid of Ithe vit(reousiS to P)ass }:beind it. flI ei p htro otils is it nfavortablo, as the separ.ation generall gtoes on until the eve is rendereld blind. itorttunatelv it is, in a vast majority of instane:s, confined to one eye. Somet:imes, however, the disease ceases to prolgress after reacting a certain ponlt, and the sight may ilmprovel and if the detaelnment is not too exten (:t rt()M.7A!tV X'IN AK 211, sive, sighlt nma}y be wholly restoret( througli the absorption of the exudation, andt reunion of the retina and el1hroid. Thle moedict'al treatment is to be directed to the itmprovtem: nt of the general condition of the platiicent, Surgical treatment has as yet beeln of no avail.,(I05IMA IIETI NAC. is the name given rb Virchow to a tumor originating in the retina, and occurringl. mostly in young children, ktnown gencrallv by tthe name o f ent celphtaloid disease or fungus hamlatodcs. In the comnumncecmenlt of the affection, thle ee apears l ealthly externlly, and thert is no painl.'Thle pupil is, however, mlore 1or less dilated, and the sigltt of the eye is gone. T'he disease is diagnosed. with the ophthalmosopef at this stat;e; a cirncIumsribed l portion of the retina is to tt ledt, opaque and thickened in applearltce. Soon tlte growth protrudes as a yellowish-white mass into' the vitreotus humor, and its vascultarl clha racter in al11 its d(e.tail is )obse8rvable.'lRapidly now thle growth increases, )usl hincg before it the lens and iris, augmentingl the intraocular pressure and pain, the cornea or anterior portion of the selera bursts, and the tumor increases still more raptidly. It assumes latetr a dark hue from exposurett to the at mosphere, exudes a sanitMs fluid wlhticlh becomes incrusted on its surfatce, landt bleedts easily. %,7he progcosis is a ysaw\ gt rave, andt eslpecially so if tthe disease is inl an a dvanced stage. If tihe ipatie.nt is seen1 early, the eye should he immeldiatelt enucleatedt; as cases a1re recorded Nlwhere, aifter the lapse of several yearts, the diseaise htas not returlned.'The opti.c nerve, 212 Ti1IE1 REITt'NA ANDI]) OPTIIC N!1RVE. in perfolrinig fth operation, should be excised far }::ack near the optic foramen, so as to inelttdu tlhe whole of thes diseased portion, if possible. I\lven after tlhe tumor has burst -through th e eye, an operattion will give the only chance of prolonging life, alnd will certainly alleviate a gttreat amot t of suffering.'!,The tu lor breaks throught, and appears externally in from one to three years fronm its commencement. Thel cause of glioma is often very obscure, It occurs most frequently in children from two to ten years old. It is sometilmes comtplicated with cerebral disease, as evidenced by headachte, drows ness, stupor, or paral.vtic symllptom0s. It is often hereditary. I have seen two of four children of the same mother affectced by it. IsXitehmia retint-, so catlled is an extreimely anatnmic condition of thte retina, w1hich is nottably of rare occurrenee, land has been curedl by rei3moving the intraoctllar pressure by ptaract ntesis of the cornea or by an iridectomyv. C'omreplete paralift sis of thoe r'tita altnd total blindness have been observed after blows, and after a. stroke of lightningl The ophthanlmoscope does not always reveal tle great change which one might expect to find under sul1C:l Ch i t'Ureut ta itces..Ejt0mbism tt th e central artery qf the re'tin is a lrare disease. I have lhad but three cases in my own practice,. T1he loss of sight is sudden l andt almost totial. Tlhe opthlltalmoscope shows at first, at hazy funduls especially at the macla1 lut:ea; but just at tthe centre of this region a stall red spot is frequent ly seen; later there is a p)ale optic disc, transparent howcver, and the o01i K-.E NFThmITI. 21 3 vessels rnnting over it much t attenated.',he arteries of the retina:are very small, and partially bloodless, so that att certaitn points of their course they may appear like white threads. Te'l, veins of the retinal present a somtewhlat like aspect, though less strongly lmariked.'%/tro'mbosis of the te.ry tcates si ar a lppea. ance with greater te nde(ny to hemorrhage*. Th e disease is solmetimet: s, but not uniformlly, accompanied by v alvrn Iat disease of the ileart. Probably the class of remedies indi-cated int ca.rdiac aff'ct ionss mlligiht; frequently ibe of serviceO in thlfis disetase. A fVew eases of ctlure' h)y massage have been reported, buIt the progntosis is -1 f ltavorable), OPTWIc-NICUIrITM. (PA PILO-II~:..BTI NITIS), Optie-neuroitis, or neut'o-retlt itisi is a condition in which the optic nerve is thil primary seat of the inflammnation. This affection is often connected with disease of the brain. Not unfrequently the ctause i s cerebral tumor, Vision is generally grcatly impaired, andl, in a large Inumber of instafnces, atrophy of the retinsa and optic nerve and blindness ensute,.1llis sad( terinilation, however, is not always certain. Even when the affection is cerebral in origin, the sight mlay rema1in uni:mpaired. A good prognostic symptomt is afforded by testing tile extent of the field of vision. If this is diminished in extent, we may expectit m or less attophy of the nerve. When the affection comes from the brain., there wilt usually be cerebral symptoms preceding, -- tt. such as headache, giddiness, vomiting, fatilro of lmemory, loss of taste, hearing, smell, convulsive or 3 C z' -I - rt- Ct ZC -4~ -.- -4'4' C~.- ti) -4J -, 4~' -I $-M. -4 — 4-' -4 —- -- o 04.z~?" - --- -U -k Z -', -3 -~'-4 -" - - -4 -r'- -4 -4~ -4. y -J a- r- Zr~~~~~ ~ ~ ~ ~~~~~~~ Zr -~ iraP -'4~ ~ ~ - -,'4 ~~~~*~- 7,JP,24.*C; -4~ CC3 - -4a*c ) C~ -~Y -h -~-LCZ. -4 - -~ -, -4~e ~ ~ - Cr.~~~~~~~~~~~~~~~~~~~~~~~~~~~J iC~~~~~~~~~ ~~~~~~ 0J -'- -d C f* r - 4, -< *; 4: - r-. l*0 - ok 8, - w - - - - - 4. -'> - -" m 6 - - - 4, tsB - - 4.,.i... _... r 4"z"....>..Y...... ZP ~e~;~C -rr -4. \' 4. 4.' - -I V 4-~~~~~~~~~~~s 210 TItE R' ET:INA AND) OPTIC NERVE. the foreheltad and tem)posra region, general neurasthenia- with perhap)S slight attacks of ivhysteria. She was perfeetly v healthy lookij,^ but not veixy robtlst. iWhen she came to ime, vision was very imperfect. Jan. a, 1867, shte reads No. 8 print with the right eye, and only No. 13 with the left. There is hype raltia of the optic disc* in both eyes, and in the left fundus, the disc and it~ ininlediate vicinity are slightly obscured by a. delicate reddishgray haze. The pupils are abnormally dilated, but not mu1el sluggishlness is observable in their response' to the action ofi light. Field of vision nearly tnormal in extent..Photophobia not marked, and no pain in the eyes. Belladonna and mercury, in alternation, were( prescribed. Jan. 24, Patient about the sate in gen teral health. Sight of right eye the same; of the left, a little worse. Acuteness of vision with the best eye about one eighth,.~.......... that is, print that a normal eye could read at twenty-four feet she could only read at three feet. Partly owinig to her obstinate attacks of congesti.ve headache, I prescribed cactus and sanguiaria i alternation nighIt and morning. Mtarch 6. Her headaches are less frequent and violent, and her sight in the right eye has improved. Acuteness of vision about one quarter. The left eye is no worse; con tinued medicine. March 27. Better, acuteness of vision three quarters. Left eye better. AMay 17. She can read No. I test type with either eye. General health very much improved. The cause of the disease in this case was very obscure. Her eyesight now, after twenty-three years, remains good. A. somewhat similar iinstiancl is the following: i - Miss A. G. S., Milton, Oct. 20, V. It. { I,.:ir. Left fundus hazy. The blindness has been noticed for two weeks. She is otherwise healthy, but had been over-using her eyes. Has slight headache. No menstrual disturbance. Slight tenderness over OV(-N EI:I'VIS. 217 the. low~er cenrvical vertebra, A Gave her i lse millm tincture live diroj)s n1ightad mornint. Nov. 9, 1.88?7 J)atient's ondition about the same. Nov. 23. Better, V. Dee, lo. Better, V. 1. Optic disc fanlltly visible. Tye more senstive to liflit~ )ee. 81. Bet tor, V. i Jain. 9. Better, V'V.: J optic disc toleral)ly clear in outline but sghtl p Th dcidly more retillitis than papillitis. A spot of tine pigmenfationt between the disc and maciula. Mic ro psia'. Objecpts at, ten feet appe;ar one half their real size. Feb. IT. V7.'V. 1, Objects appear about two thirds their ar. 8 V. -i early. Micropsia is passing away. April 92L V, samne, but eye can only be used for a short tline. Nobut the ire Opsit June Io. Eiye is get ting stronger but the fine pigmen tatiou of the retina reintins. I could formi no idea of the cause of the discase in this case. In most cases' of neuro-rtini ho the pognosis should be vcry guarded. It will, be most favorable, of course, when the atffection can be traced to disorder of the uterine or some other important function that admits of a cure, and also in cases that supervene on eonvalescence from febrile disorders, especiially if in these instances the ophthalmoscope does not show great or dangerous change of appearance in the optic nerve or retina. Niuritis deseendens, as it is sometimes called, when it arises from mit a-cranial causes, generally terminates sooner or later in total blindness. Generally speaking, it has been noticed that when the progress of the disease and loss of sight have been rapid, the prognosis is more'favovable than when the 21$ ~~nTIlE I E'nx. NA ANI) melT NXEuVE. rogres ad lss of siglt have been gradual. In til iion t.o the l*edical ta it tmst. of cou rse vav t ac i t. to the aus e, the eneral health of th patienst and the exigencies of e ach inditvi al ase. Other things being eqial, I should expect imercuriV iodide of potash, aid pho s'tthrus to L oftener useful thtan.)eltlado)nna ctlninn, nux vo.1nica and gelseim. Ctro.hat)ar.neuritis is a mider disease in wch hight or Ino change i the optic is is observed; but here Is at more or less tistin. ct c:ntral s o such as is observed in toxic ambl)vopia,. to wi the aectio bte~ars a st:.on;; resemblance. The rog i i0 m Ii volv hfavorab)le. (See n;,)appA.) Arc ph an., 1891.) AT111(1O Y ()OF I O O C PTIC V, A mark.ed sym.ptomn of this disease notic.able a-t a glance, is the ditlatted and slhuggish pupil, aand gener a lIv, when the eye is quite blind, its almost complete inmobility. Exeeptionally, the pupil retains its aictilt, atnd, i spiial 4a rasis,it It my e(vein be eonti'atcted 4and unequal in the two eyes. /he ophthadnoslso(fP (tfppei(m cr5) othelit fhmuIIds are i v'er chaiact teristic. lhe ierve d(is is pale, fhromii the at tenuat ion or disappeaoan of the small nutrient vecs sels o)n its face; theIc is bluish or blnish-green discolorat ion, espeeial ly seen in spinal attrophy; the trails' pareIIey of the disc is lost, but though opaque, its otutliiiet is distinct (see Iigs. 05, 41aftem De Weeker) thlie retinal.vessels are generally diminished In size,. nottablv the aterides; and thtere is fretnentlv an excava" lion of the opt ic disc.'his excavation must he dis ATRO:1ItUY 0()1' TI OP'TI'C' NE VE. 2.19 ingutished fronm a vervy slight di physiological one whinch iS cong'en litl illand ofte:n Se.e(n inl the1 no(.rmal eve, situated ati the cent, or a little towards the tMnlporal sidit ofthe disc. Ili tle- phtsiological excava-tion, of' caue, 1one of the synhpt(o.ns of att rop}iy above-n entionctd ol,tain, tihe nIerve being ill its normial con( ditiot. lit the atr:ophlic xt avat iot x whic is i sthallow, its edges tare gradna lv: s loped, quite tut1lik thiu abru:ptptI maI rgit of tolI e fgl ateomiatotts 4xca\vat(iot i ee i s, 3i and 41, tien e the retinatl. vessel s, in passilt into the cavitt- tiro the t(C. 55. 5'mo. 50. Atrophy of disc. from spinsl dis- Simple atrophy of disc. T(he,ase. The lamina erlbroa not stippling of the lamina eribyosa v-isible, is expcsiei. Iornial sutrfac of e li disc, o not) appear und1111(er 1 ti ophthalm oscopie as if displaced, as in gla coma, I)1ut1 de41scrib, i1c simply af cirte. Sonvet 1imes il the plvysi(o log;ical excavation tlis cirv' mav also 1)b albrIpt e)nough1 to giv- e vessel t'le.apl:pet(arance of displacement.'The patient's sig Sht is e o' l es inpair (ed, t(he field of vision contracted, and ti:e ('olo sense is deficient. In secondairy ncrvc atrophy, already spoken. of. as de to creebal ot r spinal disease, ictinitis, et c., we s ometimes find the affection a sequel of emiamhopsia that ,20 TIlE RETINA ANDI OPIC ) NRVE, is, a loss of half the visual d each eye. The aftfection is sometilmes atsso)ated with homiplegia. IU.sual l t(he loss is lateral at the nasal half of one eve and at the temporal half of'the other. See Fig FI. 57. 57. Thlis eondititoni is the more favorable for recovery. More rare is the loss of thile two temporal halves of the retina); the loss of the two nasal halves is exeeinl rare a lead to complete atrophy of the nerve I once had a ease when the field of vision ws waitii in both ulpper halves. It must be rememlbered tliat the optic nerve fibres decussate at the optic" corn" nissure, so that the right nerve passes partly to the temporal or right side of the rethia of the riwht eye, and to the nasal or right side of the retina of the left eye, Iwhile tlie left optic nerve supplies the left half of the two retimne hi at corresponding' niamier. Now, if the temporal side of each field of vision is limited, the disease must be seated at the commissure, and this augurs a bad termination. Blindness often comes on very rapidly. But if the field of vision is contracted equilaterally, total blindness is pretty certain not to ensue, indeed rarely or never occurs, unless tlie disease THE CAUSE O1 PRIMARY ATt OPH tlY. 221 extends afterwards to the com missHure, or somic nfw cerclral sv )toms aniLfest tihemselt ves TIlE CAXU OF tPRIMARY ATR}OPIHY is sometimes obscure, but disease of the spine, notably locomotor ataxy, is not an ncommn on cause.'[The )rognosis is bad. In the secondtary form the prognosis is, as we have seen, somiewhat better. Suddledn accession of blildnless s inot to be considered. an unfavolrab)le symptom, especially in children, It is favorable if the (1 isease remainail stationary for a considerable tlime, and bad if it nmanifest a: slow, bu-t (cortraill progtess. If the visual field is not contracted after the affec tion has continued for some timeit i is a favorable silgnl, as is likewise the fact of the line of demarcation etween tlhe good 1and bad of the fieltd being very d(isiinct. Irregulatr contractionlls of the visual field occurring simnnltaneously, or in quick succession, in both eves aIre tlllnfavortable. C(entra l scotmtma are unfavorable if the' visual field is much icontracted, otherwise not.) \Vhen the field of vision be)yond tihe scotonma is inmpaired, it shows a lack of the power of t ransmission on thle part of the retina, and progressive atrophy is to be feared. A.11 auxiliary or acco pany ing symIptioms are of great im)portance, because it is quite impossible to decide from the appearance of the optic nerve alone, if in manV cases theli attrophy be prog'ressive or stattiona vry. [Th.ie meditca treatimeint must; di ffter so muclth in d if Iferent cases that I do not know that I cant do more than refe.r th' read(er to the indications and i'remarks in regard to treattment made under( the ihead of Neuritis Optica. ('.I[t'A l'E.1 X 1. AMIL.YOPIC ANI) (THI E!. AF\i",CT[(ONS. AMB i lYOP I) A. Ti':s ternt, strictly speaking, is limnitted to thosl.e cases of i mperfect vision in which the afTected eve piresents m.4 recognizabhde olbjcetive svniptolmns, with or withlout tle oplt hal inotscoie,1:(1 and 1il which the im1n1:ired vissiol is not ldue to anonma lous refraction, as in hvperme itropi.a, mopiNa, an1d astivinatisis. -hI a general way, the term ainh.lyop:)ia is use.d to ex-.press innpaired sig'lt from anly and every cause excelpt t111at of opt:ical detect Thu s w Bsayv if we lind ithlat no giasses imnprove tlhe. acnteness o(. vision, that the paltieunt is a..nblyopi,. m-Ieainio lhv the renmrk nothing morve thefinite th.1an1 that the hlii.ndncss is not to he attri.bted wholly to a!aorma:I refractive powver, and that somne d isease of tli fhlnd us of the glohe is present. DIA'G0'.NOSIS OF AM iBLYOPIA, A. sim)ple, practical, and q41uite reliable miethiod of dia 1nosi, atblyop)ia. as1 well as im tpairedl vision generally, is by lthe simple device of permi.tt ingu tho l)atielt to look thlronglt a largoC p1in-tole in a blackenetd caHrd. 1: this' inproves nision, refracttion1 is faulty, and will be corrected by suitahble glasses. If vision is noto'i impro.ved I )AG NOSi. ilS AMB: OPIA 51. t 0'). 2,: the lotss of visual j.,mer:\ u' stl et sot lhtt i is onlt ofI tht' inttitr structures of the e(ve, andt. aIt ophthaltmto)seopito e.x amnat tion will lie Ilecessarv. O (co urse nice-r metthods thl.ant this to (idtetrmine.a' fiault re.fraection,'whi(n th' e requisite con'ave and convex glasses at att hand, at re tliose 1mett'{1iolted inl the chaipter on Anomalies of Retract ion: Ihut the req,uisite g (lasses are ftreclui-eitly notl; at handtt ilI the otl(ict.e of tle gentli(,tral pr:acet iti e'ltr, atlnd tlhe. a.bove, test of (:,iralld.tlttelon will prove lvery onvelu ielit. Thttomsonl s'htws thow thi tCest may lf' it;tl:md to i dictate the] exact naItre o a case of a e f an(:omalou's reftraction. nll looking:ll through l the pin-hole at a. gas-ligh':t at (t twelnt feet diistanttce if the evye is Iametrop.ie (of te fect:ive rc-:fractive 1powt-er), whenl tite ctardt is movted rapidily 1.eft.ore the evye the light will seem tin to dance. If thIe eve is emnletirotopic, tht ligtlht- will remlainl steady. In test:tillg fhet eve of at pa tilent int t!his way I f:ountld that the danllcing' of. tfl(e lilgt vwas removed Iy plermitting him.11 to look throlugl'0 No. t1 6 conl.'cave gtsstes... Iltho.sei at)ppI. red to render his eve Jem.met oic'p. /'is eye was m yopic ~1. In aniothert instanceil t'e tlithl danced wthenl tt he cartd was mtoved up. and dlown, but no t t tr;' it iwas move:td hloriiztotall t r.. Thtis itltti;ttdl atetirtopia t it inl tie vert':itcal mtu.r-idia1n, and it: w\as tfoundl b ti tial tha t ia ctonicave c(yvl indrieal glas s.s No. 83(i, the axis horiz:)ontal relmdied the defect. Thtlt cate as (s one of si inple asti igtllatisnl. W it ti wo pin-holes, one eightRhi of tan i inch a.. rtit, in the card an e nmt tetropic etye will see ol:ne light, anl alttme-. tfropi eye, t wo. tIn nmyop)ia, tthe second imag e till be.at thle rilht, in hyplSer.t.i einetropia, at 1the- left. Itn t ( catse of the mnyop.e lustl mentioned, by covering onMe of I-the 224 XAMfBLYOPIC ANI) OFTHEJit AFFECTIO'NS, pinl-tles with the red glass, he staw the rel ftame about eight inlehs at the lright of the yellow, at a distance of forty feet. TJhroulgh his No. 16 concave glass tthe red and yellow flames were one. Inl the case of astigmatisnm. moentioned above, with the two holes he l( one atbove the other, at a distance of forty feet., h-e sawt the red flame ablout four inches above the yellow. Hiis cvyi ndrieal glass nearly fused the two ilmages. In determining a hypermetroplia by this method it will frequently btie ntecessary to first paralysze te te acctrommodation with a solution of atropitnc. An emmetropic ye may easily bt ae me to test theo correctness of these various methodl:s b)y placing before it at convex glass which rendters it myopic, o a concave glass when it becomes hypermetropic, or a cylindri al glass which renders it astigmatic. CAUSE ANI) TREATbMENT OFP A.MBIIYOPIA, Temp orttarly congestion of the brain and nervous structure of tlhe eye may ble occasioned by suppression of exhalations from the skin through exposure to the cold or wet, by suspension of the eatamt nia, anl by large doses of quinine or oiler l'drug:s, the result of the congestion beilng dimness or ntire sllsplnsion of visionl. T'le ievers(e of this, a dimintis-ihed supplyll of pure bl)ood to tlth lbrain and retinam, will also produtc amtblyopia. This enfeebled condition:'01 l(ty e (ttt. du-e to s(ev.ere illness, excessiv er draint on t t he system t'hrough elmottrrhage, utei:cine discftargtes, gestationl, infanlt mlltrsingi, aind like dbtilit-:ttin-t cau.stls88s, In sutch instances of impairedl vision we should not CAIUS]E AND1 TREATMENT OFl AMBIAOLYOPI'A, 2 nD( fl c c; t n I1 titlt e moscoplic examin at ion. ur vl ogi -: nIosits will b1e unce ltain u less we can first; establlish a (.Iorrect di atnos111 isX0is cam afis bi al dorn, liut it clan ofteln ibe dlon. liTh't fact t; tht:the ophatllmoscoi c cxaMit nation frcqcni:Nl yviclds lbtt negative results is of it'slf a. fitavora.blet om(flt for the pf.trognosis. So(ettimes the exZamnititition of the interior of the eye reveals c1noughl to make thi future of l the patient extre mly doubttful A, few days siInce a ease of am1lIvyopiaN from p'regnancy at the. eiglth m.onthl.t w-as sent to met, and otn e.xalinali on I I f:und on optic t uri.tis wNIith consitdrable effusion in the retina. T.,he prognosi nds eeds to le extremely gttarded in sluch instanl-ces. l ess pitercept ibl ch.tang:Ce than this in the It unldus of the fglo:obe are fol'ltowdi by permanelnt iltmaiprimentt oif visiton. A,. ntltl),ber otf cases thavet bee) n t publtislhed int wh}ich the b'lilndness o.tf tpregnancy has termimnated unfavorably. Wt e lt ave matny remedies suitable for conlgesti on of the lnervous tWiic of tlthe ey e, suchl as cactus, lt feIadonna, sanguinaria, plhosplhorus, glonoine, and ofthers. [-o t pedilnuyvia: are somett:ies strviteablte, alnd:thet jliciouls tlse of thte lTur{kisth.blth wif ill c.t'itef dtisordered fluncti ons of the skint. Th'lat the l(Tu' rklisth bat:h w\iil also diminish { thet flow olf blood to to he brain li:ls been plrovedt bily optha lmloscopil c examiation made beforte ant aftcr shoulxfd e, Ipre'scribed. Hellm.ienorrhagel and all unusual 15 2(2 AM BILYOPIC AND) OTlhIERt AFFECTIONS. drains on the vitality of the patienlt must: be ct::ntrolled before imlprovement, ae n b}) looked for. Blood poisotw, y, fron dtrugs like lead, and narcotitcs like alcohol tand tobacco, will produce amblyoi: ia. Tota l IatSsititenlnce f'rol at lcohol t and tote)acco would seem to be the only courset for such as ca:nnot draw the lline )e.tween a stimulatizng and iarcotizic use of thelle substlanes. 1)rlug l)isolning requires a specifi line of reatm nentt for each case; lead poisoning is said, recently, to be successslfly v treated by opiuml through t(he hy)podermic injection of morphia. Amlilyopl. ia nmay.L be th( dtirect result of bl.ood ptoistoning, but \evenll int blancthing and all'ppa.rentt,at:rophy of the opltic nervel, a very g1rav1 s'ymipt1o indeed, there are i any catwses roe corded i. which a more or less lpecrfect recovery of visioln is known to have tatken place after the latpse of months or Vyars of lOiinldness. Quinilne lindness, as well is deafness, is quite common. lt often plcs ofis f.rafthr slttowly;and exceptionally 1 imp)ttairs the sifght plermanentl t. Salicylic i c aci so ad as als o ased ambyopia..J)Dettal net drati sometimes in ttnpatirs vision,01 tl lhrou'}g reflex irritattion fr)om a branch of the fifth nerve. itemov:gh the m:edin of lthe symlpathetic nerve, somen disturbance in ti:e nervous structure of thle eye wherebylx vision is itlpaired. The same eff(ect is} prodntlced on the sight, (cc(tasi;onally, from nervous otr othiter apl)parent:ly slight affect iot.ts of the uterus. Int factf, retlex disturilbance of visi:on may inl st801l( instahn.cets tbe dfue to irritaItion. of any part' of the system, inter-nal or external. in such tcreit, especially if the oph.ithalmnoscopte shows no changes in the interior of the eve sutfficientls mar..ked to accout.t for the visual disturlbanlce, the treat mtenut must be directed ch icfly to tlhe removatll of thle exftra ocular lesion. SIMULATION OF i3lNI)N EPSS in onle eye, by nervous or hysterical persons, by conscripts or prisoners, is readily detected by holding the finger or a ruler midwa y between the eyes and the lprint while the patient reads* If the patient sees with only one eye, vision will be interrupte d, if with both, not If this i noot wholly satisfactory, by moving thle ruler 228 IAM IBLEYOPIC AND OTHE:R AFt I'FC:ItION(:S. slighltly frlom siCde to Aid: s0 as to cover each eve in alternat ionl aty furtlher simtlation of bitlindess will ge.nt e lly tIe d etcdetdi Thlt dccet )tionl may also:) e show n by mtans of a trisln, base in ward or out ward, beIfore dlth normal evye. 1i1 tlhere is a corr.ect:ive sq(uint or elilnge in tih d(ir(ect(ion o tf he eyes. as tle prisml is remXoved, linc:)lteu tar i sion 1 proved, or the base o)if t() he pris'm bleingt tpluWartl o-)r diownwa.rd, if the pattiet stees double., tbinoclar Avisit i is eertait. The stercoscope o1( may also be u1sed as a test, as b)inoltlar Visio is re(tisite iln order to a l'l)reciate its e:ffets, Simnlation of hiindne:ss mi hoe.th c/C, may som(:ttetimes tbe dletecteld by obse.'vitng; th]t e action, ofl t ligtlt ot the sizep of thle plil. Mobilitty of the iiris 1(lunder ith.e stimt lust of lillht' is a tolerably surle indic'ation of sihti in o(:ne or btf th (1 yevs. Still, tShis tes; is not absolut)ely eone'lusi ve and a bilateral simulattion of blindness maty rtlove dil eultl to )detect. HiEM tALOP,(l 01 I)IOPAt'i' I 1C NIG H(1T BLINDNE O!SS, is genterinally sconsidered a Ipurel functtional disease of the rettinal in which no changit's are obtservat}ble vwiilt th:l e opht:'ha'l hnosc.ope:.. It is an affectioln conin-led in it's oriigin almost. wihnlly to warmt) climates, amnd will be remllembl.ere:~d as onhe from whlicl our soldiers'on dutl in ithe extreme Southl suffere(ld considerablvly. Sailors inI tropicadl.re(,gions arto' also frequent sf81f lrers. T.he dist:iinguisiuiing chlar.acte.ristic f theis is, a torpor of the retina., so that a: bright light is requir is nre i red int order to sitimulate it slnfciientily to receive (istinmt ilp)ress - sions of objects; hence by night the patient's sight is unusualtly bad. The time of the day lhas no signili COLOR IBLIX)NESS. 229 caniee, s:lnh as the namne of the ll ffTcction would indicate; for by a tbright arti ietial lighlt, lte seels as well by nigtt atS if no attf:ltection of the eye w\ere'l: prest. ItIe caitlme o-f the (liscese ise exp)loslure t:o g'lare of light, Iand i1mpove-t rished condition of the blood. lf):.t tllhese condit ion)s arte prelsent witll our solldilers and sailors in watrm latittdes. l it is often mlet withl iln.l onjuntion with Inaltaral"1 fevers, a(n the i ll-ft.ed andl t ill-tthoused peasants in the south of lEuropel and i:n C(ental A. mniericat artc 8subii(.ct to it. Sailo'rs afflicted with s(ncurvy art oft:en subject to it.'The ti'reatdment is veary suimple atd effii:cacious. el'l tst, protecttion of the (ees from I) ig'ht ligltht, su(ch coust:ittutional remedies as artre necessary for tihe'restorat:in o)f the gteneral heallt, or change of climate, genrally cure speedily. In. t1aly, where tlhe aftf.f'eltion is qutite coinIIIo( a poptlniar re'muedy aVmono'g the p:eople is fumhigation with the vatlpor'froI the liver of a sheep or orothe(r an imal. (tQuagllio and lsot me others lhave obsetrved s'vmptoms of retinlit-is in the opht:hal)moscopie attppteatranet. ( of the fuld.st of the ever in this affeeti)on. Nilht; blindtness is a p'rominen. t sy'nlptoma also of the disease called r.etmitis pigmen. tosal. In tllis aff(ection( tihe fihaeld of vision:t econt'esI limited, a su syubjctiv\ mtom which' is )lot. o:ften ob.served in idiopnthic nigiht blindness. is sometimest cont enit(al. In the..so cases there is uutiall am. ilnab)ilitr to distinguish the shalsdes of red. and red fSrolm its complement ua ry color, green. ( lree.n-red blindnesis is also a symlptom noticed in at ro.phy of the 280 AMB:I YO)'IC AN1) OTHIR:l AFIFECTI.ONS. optic netrve. At ckl.romatopsta, inability to dislingutish all colorst, is usually tlie to disease of tile optic nerve or o)tic nerve aId retil a. It has been noticed also as a synlmptomi of m1iyehitis, Y'/tc dia.tnosis by' the I folmllgrenl.method is simplet and cal be carried out by any plhysician who wtill taket tlhe t:.roluble to provide a pdlentiful collection of small skeins of worsteds, abou0t one hundred int nulner, of the primlaii.ry coloirIl and their di.fferent; sitrhades A. A stein of light greentl,:for exams ple, is selected froml the ma1.ss of colors, and the pattient is asked to select other shades tlat at'ppear to him the mlost like it in color. If lie hesitates alt l steleets fitallly grays, ineutral tits, light btrowns, etc.,,he is color blind for green., iven a light tur.'ple or r:ose-colored sam: ple, if tte matches it withl light gf-reens, gnrays, and light reds, lie is red.-lilnd. tBlue-yeltlow blindness i.s very rare, a td congenittal total t:(olor blindness is aslso rare. IiYPE^ttsiSTiTflSIA rlfEIN.T;,> Oft REI*AL ASTIItTNOPIA is tcaracterized by severe,tpotophotbia, laeh;t''mation, alt:i all the symptoms of tan irritation of t1he ciliary plexus Mof nerves. Ihere are no ophtthalmli)soIt.tpi chaltges ot:bservabl'e inl the fundus of t:ihe globo. In cases twhlich hIave come undelt r my care there t hs 1been, ut i formly, dilafattion of the pupil. The siAght: is good in a diminiisheld lightl but the field of visi>on is usua lly sometwhat contralcted. It oeccurs mostly in young fema les it dellicate health, of irritable nlerves, hysterical, and suffering from catametf nialt disorder. lThe disc.aseS of the nerl:volls structure of the eye is but an indication of the state of JIYPl;1tSTHESIIX A tETINA;., 231 the nervous systeml generally, adl the treatmenttl murst be directed to the removal of the constitutional syvmlpt oms. I have found quite a variety of retedl ie nceslle sarv in dilerent Icases, andt stomet:imes in the:tae ae Case,. (Of course errors of refraction must be corrected by.)'10loper gtlasses, and. then theii indicatiolns are to restore thle tgeneral hetalttll hlth such it reatmentlt; as may be neessarl. If ltphto(phobitt bh present colored glasses shouldu be worn in the open air, and it mayl be nlecssatiry to moderate the light 1(to a fcertain extent iln-doors. I hlave never. yvet found it nece:essiary to c.nfitn pe}:)rsons f(or dtays in compl et'lie darkltss, as las been I ratised ad recomlniSended. indeed, it; hats sieem.ed bett.er to clcourlt'age the pati)et in atte mpti- ing t t o accustom h t e'eyes gttradually to the daylight, as te gelneral }taltIh is improved. The st:rontig lightt is u-tpleasant:rathler than injurious.. never hesitate to nse tih op:hthalmttosope freely in these cases, titrowingl a stro'ng lig)hti dircctly into tthe eye. No.) seln.sitiveness whatever is not icd ti under til examinnat:in after the fir st.few sconds, andt I nevelr tard of ay aftert ill f I:'ect ts. Atft2:i'stlet.tsia ti. ('n-c is ae ction )lroduce by exposure of thle teye to extrl ly brighlt light flor a long tilne. iSnow tt lint lSs'8' is a form of tthis disoxlrder, and it is frequc: tly bl:rouliht: on tb continued application of the eyes ( nt.der st-Iront artificial light'. Thte,blinlldness takes the form of a cloud before the eyes, antd may e) of only short du ration, or m)ay contiinuet for weeks. I was the sutlject (of a( similar affection myself ttduring. the pastl suimmetr. After gtazing out )upon the ocean fromn a pleastant w indotw fort an hour, on going downt on to the gpreen 823 AMBLYOIC AND OTIIlI AF'I:ECTON'S, lawn\ l I ftoulnd that tihe grass atppl aredtt o be veiled bI tn exc(eedingly delicattt le blt hazte. M, friends declared lhat no sntelt haze existed, andl at afW m I nuftes,' rest, I saw no tmove of it. Many11 cases of thiis kinlld alre lmorCe serious ttlttan this-.'The symptoms wlhlen stevere tare similatr to thlose mienltioned below tunder the e't',.etfes of electric light., and may require for paili atiotn at prt).lonu ed exc:lusio, of te eyes fronl light, soothitng apjtl icat ion: t tho thI lidts aln general const itutional t.reatment:; bltt in tlhe end tihre is cotlplete recovery. AFFECTI' ONS f)''O'11i E EYEIfS F EOM SUE TO:' T HEf BEIC('tlln LI.,1G HIIT. ii.'Exposu1re to elect'ric light nmayl be p1rod(ucttive of a severe (aflfection, btll is ordilnarily not very seritous in charac(. telr, nlor of lontg durtation. t'.ier is Iachrymation: ciliary ir ritation l, i sligt t swellng of the li ts alld of thlt ocu lati conjunctiva, and slight sensitiven:-ess of fthe retint to li ghtt. tnhese, isturbanee s generally disappeal)nar in a f'ew da ys. In1 severer cases tiho re:ietina sullers more; there is a: c0ntral scototna atd intense photophob'lt, ia, t og(ethecir with tle otherl synlptomst common to tLh less se'vere formn. Such attacks usually pass off iln a few days, but octisiontally a lon, gr ti ne is lncessary for tlhet restortation of the nor-m. al functionls 3of the retina, as is shown ty a ase under my care laar-st ye ar. A. wnoman of fifty, of ie ur(,ltic tendency andt iltmlired vitil it:aty, had CxtlpiosCd her eyes for several evenings to the. g'lare o'f tan tare lihit il tile street o)pp:site her window. I saw her three wee ks after til expt)osurett on A p\ril 8th1. "here Vwas severe Ihotophobia, rel ativ e centralt scotona, slig tt H'YSTE1.1ICAL AMiBL:YOPIA. 233 ovat l vcrticallv, and V. l. was {l2 I; I 1. J11 eild of vision not conitracted,. (Ohthal nosotic s ign s wani;lg tRest of vets, colored glasses, and care of gncrail haltht by her p1ivsiciai, were prese ribcd, May 3. Not much change. Jtit 3. B i ttr; re ads with 2.50 D* July 1 V. II -;. U.1 Nov, 13. tG(:eneral lhealth good. lPot:optlbia still, bult it is now quite sli lt. V -1 but t site does not t read No. 1:prit quite as rdily as f ore rily'In this instalnmee some seven months were required to restore the sihtlit to its normalt condition,'Th. irrit:ation of the electric li t1ht on the eve is du tI to direct expos ire, and is produced by the ac tion of the chemnical rays, (Widmark, Oph.'leview, Vol. VIII. p. 172.) H YST'Tti(A, A MXBLYOPIi A. T'Ilis dis order of s iight, so far as symiptomns are concerntdt, is ne arl allied to a ns;tsl8si and hvpcr;esthesia of the rctintllla and is seen in those sulttel, fron. funct:ional or (ot}her( nlervous diSsease,. Th181:rce mavt\, however, he a mnllt11ittude of t:ler symlptioms i th:lan tthose me ntioncd tnmder the above diseases. Sludden andl co(i)plte blindness may occur, and as sitdldcnly disappear. Or'there mtay bc central scotolma, (or henianlfopsia; and there is sometimens a strongly abnormal color sense. The trcatsment of fthese cases is often tedious, partly from the ftact that often no atdequate cause can be dis 2834 iAMBILYOPIC AND) OTHER AFFECiCTIONS. covered to aecotunt for the condition, an:d partly flro the fact that the nervous or miental state of the patient Imakes any treatment precartious and depetndent,. FiEvery kind of treatmlentl is accredited with having ctlured tthse ea ses: ttrtgls tiv tlhe score, h ypnotism, faith cutll, mind cref, tetallothel rapy, etc, MIy, limtit eed e lperience in the treattment of these cases is not cleatr enought to warrant special advice.'The progno)sis is good. NEIU-RALIX A OCUI., is usua.lly associatcd with, or is mrcely a symptom of, a diselase of fthe eCe such as iritis, chtoroidiitis, glaucoma, )t r soot oither alefctioln, the treatmenltt of whvich hast } lbeen atready indicated. in hysteria, it is bitt a phase of tmhe nenralgias conmmonn l in that disorder of the ncvous system, aldt can only l) cured by restoring, the general ]health of the pat:iclnt. It; llay'I ) relieved by sucl mcasnres s s are recotmmended for ci ia ry neuralgia. I htav e oil 0110 occasion0 caured such a ncurtalgtiat itn two orI thrce mi illtes by the instillat ion of a drop of cocailln into the affectedt eve; atd only one instillation was neC@cessaryI!, CIHIAPTEIIR XI II TI'lE CLIRYSTALLIXNE 1 LENS. CATA IACT, (' xATAi CTr is an opacitxy of the lemns, its capsule, ot0 both litc ad tcapsule, ald may i teroflfo li calle d le t'7ticuftar, caps'ulart, otr tcap. ulo lenticulatr. DIXAGNOSIS. Thie,std^te scjpti', stl. alt e (iiflCl: ss of v. sion, in pro)portion to the ago or ldesity of the opacity, wthich incr eases girad uall, exet. e it in trallmatic cata-ract lwhen it lnatv labe sudden l, 1 and1l in c(ltVongeitatel eaittract. The patient; sces better generally in a dim liglht; because, tho pupl) being larger, a pIotio l of tih lelns from the'entret towards lth p}erilp)ery is ulnoverled, and this pn'art of tle lenis is tusualltt1y clearer t hian thite cenettre. Fl'or the same reason the instiillation of atlropine improves visison somewi hat. XThe tirst, symptolm lsnial ot-iced by bthe 1 latienlt w\ ith beginning cataracti is, tlhat distiant; objects appear slightly habzy, or as if suurrotuded by a htalot.; aft'erwar'ds, as the ca taractt dtevelops, vision for nealr objects is similarly ima)paired. Oljecthire syi..pt.t' n -t,^ The pupilt is tgene(rally normal in size antid moav'tement..he vacanti; look, rollilng of the eyes, and tendency to look upw ard of.anaurosis are 236 T'.HCnE CltYS'TA'AINE LENS. not present. Tihe I)atient is ilclinecd to look downward, tand is able usually to fix th leC s on o el: ts. If the fleet tion la(ts madte considerable pro''ress, a gray ojpacity is at once notice1d exactly fillinty ting t are(a of the pupil, Fmr. 68. Nuclear cataract 1. —. Section of lens. 2 a Cataract as seen with ophthalnlm o sopic mirror. 8, Cataract as seen by lateral illtunination. the opacity being sharplly limited by the pupiltlattr m.argin. A.l, corneal optacity tinay hlide: a portion of the iris, but a lenttictlar opacity can (. only obscure the pupil.'the pl)pil shouldt t b enlarged with atrolpine, tand the eve ex tamined b oblique or lateral i tllluminati-t. Ax't:?amitio n by la/ f al tt ailtmi:atlion ) enat bles us to delterlline the extent and nat.ure ot the opacity, lwhether co'mplete' or ripet its color, its forlat ion), wlcther nuclear or striaited, and otlher details.:Direct ex:tamin ationt witt the iophtbalmoscope is ch:i eflt. serviceabtv)le in detttctitng slig:t lf; and tbeil.nilg ot)aitv of the lens, which would oth crwis esae e sca obsrvation. lThe light. sfhould not be very strong, andt the eve of the observer shotuld lbe twelve or fifteen i. cells from that of the patient.'here ay be a geneltra, but, ver slighIt, cloudiness of the ie ol lens, or the nu.'cleus a lone may be obsure (Fig. i8, after Nettleship), or delicate stri u matxy ( eb seen rtunning from.t the peripliery towa rds the centre of the lens, as in Pi.. 59 (Nettlesihip). These opacities will appear black instead of )tIAGNOS:S OF(i C kATAR ACT. 237 gtraisl, ass inI the lateral examinmatiot. Beginning catatitir'at maylt: b.t conlfoundlteld with 8sepa ta ion of thi rttiinla, a fact wtAichl is not:iced under /te.'tinal i)iseases. In ctases wthere -the catartact, is denAse or far adlvatncedi FI(;. 59. Reft rencs a in Fig, 58 the othalmoscopie signs arc nega:ive, as io light can be throw'n into the eve. CoMpt', CAfl ON, \WTli OT IlXi: 01111 I:K 0)' THl: EY.,.he'lhl molst clonn'on I comti)licatf ions are' -.-.he.results of irits, Softenlini of the vit reous lunor, (Choroilit is, Sclerot ico-chlorodii is t posterior, Separatitont of the retina, Armbly'op.ia.. We may deterunid n.i a compljiation or its albsece, 1)y te.st i tig tthe patient's vistual power aftehr the ea.tarac is ftllly.niatured. lie mavy b) a1ble to dist'intrgisl niUltt fromi dat, or the lig'lt from at window, attid to note a: llhandl beftore his eves, even a.t a dtistance of thlree f.t,. and stil we s lould not 1be justil fied in pr1onomtctinit a thlt retina. sound bleyond a doubt)t:. To ren(:,der the abse'nce. of all comnpiicat;iois sure, the patient should h he able to discern a dim n lii'ht; in a darke.ned room at a distance of ten tofifteen feet,.T.her. should be ino c ont raction o f the field of vision, as tested bv monving a ligohted cand le from one part of the visual field to the other. The patient' 238 THlE (CtYS'It iALLIN,'.LNS, eyes should tbe fixed otn his finger at tlhe distance of a foott duringll tlis ts est, and tile candle lt lc sluld i thaded while its position( is bein'lg chalngedt; the telnsion of the evebatiI schouldt.: e n.ot:ic(d, atn ilt in cases of tdout:, the whole histor:)y of the failure of si iat investigmated thorough.illy. fPain, pthotophobia, flaslhs of lighltt, spectilra, and like sympl)toms are to be regarded as Indicating n favorable. comiplicat:ions. Timr CAUSE OF CATARIAC' is )praobablly fali:ty nut:,ri tiion of the le:ns. itis may occur in old al e, as in senile cataract; in dis;ease of the kidiney, as in /diatbetic cataract; or itn aborm al c:hanget in tlce deep structnure of the eye, as in secondaryt cataract. There is also a congenital cataract, dating from birthl and a tt.ra tt atic eataract from injutry,:leenectly, inves tigatitlons, by SchiOlen, in regard to the cause of senile cataract appear to show tiat the. opacity beg,'ins frequcentlyv in those from t.wenty to thirty years of ge, and notably in hypernetropic and astigmlatic eyes-, in the form of smlall white dots and streaks at the equator atnd in. the horizonPtal meridian of the lens, Later as age comes on, tle opacities de4velop until the ianterior corl tical atnd ituclear portions of the le:s become involved, and then the failure of sioght is first tnoticed, Anetropia, dleicient refractive powver or errors of refraction;, may then be considered one of the primary causes of senile ca.ta:ract:, ()pacities of the len s fall, practically, into twg-o great divisions, the hard and soft Vide A. of Oph., vol xviii. No, 38 1^^ R 11 i;;' 1^1^ ivz. li 1^ 1 I. ^^ f _ / \ t oS >- c O - 94 w:v ^ ^ ^*~ ~ ~~ / O O 4 4 O 5> ^. 6'* >'>' - W _ ^^~~ ~ ~ ~~~~ w~ ^ +,,_ r,0 r;, 8o ^; > >_t^ ^^ 1 \/ e I < o ^ F ^ _ * ^ - _ 4 l >> -^ i ^ _ < w b Pss O X _ F~ _ >~ -~ _-t - - ^. <#Q \X?"~, oO< o-^'^^ >_;> ^ _ _' - \4 G ~ I ^ - ^ l"^ > i n r -' ^d - J:^; \ / ^. 7 F r *: ~L "" ~^- = r~::>,,^ ts, C ". -, "'V- p- -s o.,f;W - ^^~~~~~~~'" 11^^^^^^. - 2_~~- - cc ~_XOSo 1?'1 I I* SO_ l: ~l, li _ ^ll 3 ^. 240 THE CREYSTATIA S NE'A;`LENS. 7he.iro/tress of htard cataracets is verv var iabilel(, s8to ti nes sl\ow for a itne, and then raptt idt. They'ay, ind.eedtt fort a tie l.not only ceatse to ptrogrlOtss, Jbutt th1e (patient may, tenlti)ora-ily, see hletter. It is wiser t- n lot to anlswer the invariable uestion oi.f pat:ie ntts decidedly, as to the t:imne lwhent the catara::t will be tperfet It: is ve.ry c.r.tain tlhatl;t ti e o)rdintary se..ile. it:t (c)ata t of one eve will, sooner or ( l ter, be f ollowed t)y the samc affection in the other.'iti tB OPERIA'T'ION 0' E;XTH'IICTION is indicatte'd as soon as the eataraett t las ipene.d.'Wte Illtay judtge of thEis l)y the app)earanlce of the opat.city wh\ich is 1denser, deeperl in color, aild extenIds through tlth elltire le —ns, so tithatt thl shttadow o:)df the iris at the cireumtlferet e of:the letns is8 sc trel visible. The visi is also r(eductd to th te lmere tcountingt o{ finlt-ers. Di taiion of the plpil wi tl atropine l iprtol:)ve it less, as tlhe p'eri'lpe of t het lens is ivolved in the op)ac ity. When tle cataraet niatres r ve ry slowly, it has lbeeI n recomlmende'(ld Iy if)iorster t o hasten its d( \'velopl:lIentl - t' ytl li at preliilnl itnary irtii1de:tomv and ru.l:)ingm the'orn:ea over the pupil aid lens capsule.'We may also operiate be1fore the catartaet is full y ripe.'The disadv antiage of t his is, th:at the tlrant sa. te It (l' orticat l lol't ion of the ilenis, hleiln soft'er thant the opaqtl part, may' s.ep'arate Ifromt it, a ndt b:e left to a great:, extent: in thle eye, and tct afterwtards as a for0eign t)od(y, irritatingtlr the iris, and prodnelnigm distturbtance of v isionl. Tt: is safer not to op.erate on both tey'es at once, TH1IE SMALI FLAP 0(1IATIO N. 241. THrtE PROGNOSIS, The p)rog:osis in extraction is v'ry favoi'able. In ulncomllticatteld cats t here afrct probably not more tihanm thllre or four per cent um of ett'ire failures. T.ie ope(rationls mostly ptra(ctised for xt.rac:t ion tar tth stmatl fla.p, a nd the pe.i'ereic.-ltte.r.'l.the st rit poteripheric-l i near operatiion of (: rafe is losinllg grount d wtith operatt):rs, f rom,' t1he dtanger of irido-evelitis, which mlay follow it meldiate:ly, or after the lapse of considerable time. Ti S 85. MALL. FLAP OPE RATION,''}he patient bteilng iln af rtcut lclbe.nt position, (an assistan:tt separatt.es thte lids, or th ey are separa:ttd by a spe utlumn, the ('ope'rattor fixes the ee eye Ib pinchtingt up a fold of the conjulmet iva:r wlith) a pair of smnlall forceps..lie then lente.rs the corina, at its outer edge, eithcr at its upper.......... it......~.~.............v......... Fio. 61. ('iraefe cataract-knife. or lower third, withl a (- -ra.ef cat:tract- tknitfe (Fig. 61i.), carri(es it st:eadily forwaird, cultt:ing out either ab)ove 1'r below, and makilng, according to his predeterminced intention, citlher sluperior or inlferior l'ap, I.::aq................ —::.:.:.-..................'.: Fm. 02. ceer tataraetuknife, frmerly utsed tfor imaking the flalp hi ex-t:actiton Allowing the patient now a moment's respite, the eye is again opened, thle tneedle or cystotome introdusced 16 B2! 2 TIi HIC CRY TA 1, N L NS. (Fig. 63), and the capsule of the lens thoroughly lacerated, This being aecomplished the opaque lens, with or withont; the aid of gent::le pressure upon t Ahe eye, emer.es AN ltIlhout the aild.:)- of g-rentle procure1c upon tle eve,eergs 3fo. 64. Daviel Cu ret to. mains of the soft coriical substance of the lens are e'actuated -by (vent:vly apressing h lie cornea fthrough the lid and by rte aid of the cf te uremtte or spa tula. 1 ig. ( a )t. lx operators make an iideet:om aftelr cmpleting the flap antd before the evacuation of the lens; a few make a preliminary iri:dect:omv about fou r weekis before operatilng for extraction. Ei xvigenci(es urmaV, arise duiring' an operatfion like this to modify it somewhat. The corneal wound mav have been made too small to adnmit of the pasSage of the lens. If SO, it mst be etllared y cutting with curved scttissors, a p'ro'ceeding sometimes dific.ult, the cornea: Iinlg directly uponll the iris, there b}ing,, no anterior chlamber in conisequence of the escape of thle aqueous humoir. The knife may have entered tfhe corneia t oo far from its lilbus, too near its centre. ]n this event, it is necessary to cut; out in the sclerotiea, and the wound will lie towards the inner cantihus of the eye. This may render tedious manipulations necessary, a fter the open PEmiPI IF: IC-LIJ NEAR nX'riz ACTION. 243 ig: onf th: e ca;tps I e, in ord1er to force:lie lens inward to a poi nti correspond ing to the openingll of tlhe wound. tfr I:)-I~t t f f-ol. Somnti tmes, after rui turing the c. apsule, instl ad of the lens, we have a gush of vitreouls llnuor firomn thl o outih ofi the wound. In this cas e, it is necessary to remove the lens imme diatel v from n tle eve, by Imeas of a curette, or smnall spool. beep-sated.'hemolrrhage may occ1ur1, especiallv if the'comiplication onf glattcona: existi andt in suchl evenlt tl he p::r'ognosis is bad. Ow()ing tv o sudden escape of the aqueous hIu.oll(., the: iris may be forced atgainst the kn life, and wo tunded id, in mak:in th corn eat l t( la. TIhis mart render an iridcctomy necessar y Tl opraltion.:for exract nl.iont is done under cocaine. The instruotent s are disinfcctdt, atlnd the conuinctival sac thorougshlyv cle ans ed with a solIt:iion of bi-chloride of mercury 1c 5000 before:lma:.ling t:hl ctoriiea.t in cisi on, P -lRt I ri rIT.- E.R N E t X: X A CTIO() N, Thi-ls operation, of'Von G(:ratefe, requ ires lthe recl-.'.'bent; position, and the lids to he s'eparatetd b)y a stop-I:' stpecutiumi.'he eyve, being lhe.ld iX positit.on hr dJe'licate forceps in the left hand of -the operator, is en tere. d with the Craefe Xknife, the edge upward, ii the scleroit ic, about half a lin f ct m the corneal limb.us and near:t its uppert'and outer port itn, so tlhat the anterior clhitm iter will bt openeid across its extremte upper n11arg4in.'Fi, 6(, from N'>ettcsl:sitp, slhows the varied cornical sections in cataractf operatiotls. Th'lte knife, lbeilng enttered at. the temporal side, is 1pusl'd downward aind inward until it: 244 T! E CIYSTiAi uN LENS. las eterd at eor ctber. th'o anterioc th extell nt of two' or three lines,t wihe the titindle is depressted and the pointt is caried horizontally f)orward towartds the nasal tmarp:itti of t:he cornetlct, o as to lttmerget o iit thle sclerotic exact l opipo(sit e it ptlaco of ctrtr ance; the edge of the iladte is then tturntted shtarplyt fotrwatrd, the knife pushed horliontal 11 otnwatrd, and the sct'iont eomplleted )y\ dratwing it backward ftromt heel to poin t l'tt e next step is to, - IFo. (G. Line of incisions in extriac-ton ofnet:s. Old flap., f2. P'iplhel lainear. 3, Ul.ier anid low\ir lshiot flap. D)otted cirelc showVs outline of lets. lmak'e ant ilrideetomrv hyv seizilg the iris'whichl prI'esents itself at t:he wotund, and snipptig it off.'1ThI ea:tpsl:ett is tlen licerated, 1a1, 1by genttIte p'ressure 111ponl theo eve,.the eatailraect is foirctds throughl the opl ing. If, as s::omn)eti:imes llhappl'ens, the len is Inot readily evacuated, it shoutld lt) drawn t: rom the eye b:y a, s11mll slpoon-likei tiract or or cureltte. The oldt process (17t30)) of svringin oult te cortical remaitl is again r1eviv\ted; but it is olne ml:ore manip:t ulationl of doubtful tnecessity, andl olne doul. tful Imanipulattti.on is undesirabloe. t It ymat I: o said, furtlter, tlatt Nulel 1has fotun, by Oexperimentt that pulre water iltnct d ijectd into the titerior clmn ilber causes a detaclnenti; of the endotthlium of':)esceenlt's.membllrane, in a half minute or letss, (Arch. Ophtt., \'Vol. XI X p 806.() 11 tCI.J NA.T1 ON 0)1 1)EIPl SSIO(N, 240 EXTRACTION OF TIlE LENS WVITI CAPSIlA.,% An opening is lnadle in the scleroticot or.the corneoiera! junctionl, followed. b)y a11 iidectomy; a soo thten introduc(edd be)(hind the, leons a1d.Capsule.) tiI and. )ot )h are extraocted t(roether. It is often done for hyper1iaturte ataraects. ilI(CLNATION ()t l)EPIRESSION for senile ca taraoct, b justly fallen into disreu)te, and(t i seldonl practised. T., eve i s entered thronugh the sclerotica, ab)out two litnes from the c'orinea: at the tem)por(al side, just be.1low the horizontal me)idian. The needle Jmnploycd is delicate-, flattened, an)d spear-shapled...:::::::::.:::.::::::::..: -.:; a.::...:;............................ Flo. 607. towards its point, and double-ed(ed.'See Fi,,t 67. It is carried forwa rd until its flat sturfa-e is directly beh-lund the pupil, anid against th.c anterior capsuile.. Ti lens is then} pret',ssed geently } )ackward and d ownward out of the field of vision. Its effects T are, brlt li1an t ti rst,.ut not plermanent. Now and then there is an exceptionally successful result. I saw, dutringl te h'semester of t1803, in Vienna, a m1an whlo had reel intion p1rformed for cataract in the year 1839, antd now, for the first tit ime, was troubled l:by ildist.inlt vision frlomn a shred of op)aq 11t capsu le. All eatar'act operations are now done un111der cocaine. A 4 % so)lution is dropped into the eye twice or thrice 4:0t tii ) TI: iHE Ci l YS TAL. *,I..I AiX:* N CS at fitve-miute ilttcvals,} and strict anti-sepsis is otserved as il other surgical operations. A PTEI TRlE.ATME XI NT I N EXT( ACTION.After tihe operation' }both eves should be gent lv closed arit a sim t i bandage ap t })I d ats dscribed i chap l ter third under t andaig,'. tche banldate and char)ie or anti-septici ablsortlent cotton may be renew\ed every day, thll. (tisct.hairge ttrenlytv wtashed away with tteiid water. At tentitliot s of tlis kind re tder the patient lore t co.in-.f)ott.ab: quiet, and less lt.ervous, and so facilitate Ihealiilt, anItd a f1ortulnate result. Tie I tient should kteep tis led about b fou t rt v-eighttt hours, antl then if all goes,(well lie 1ltemay lexch tiange it for the sofa. lThe' ttbandage. may be comntinued for a we(ek, and then be replaced by a brotad shade, andi tlhe sooner aft:er this the:patient can gVt jnt.o tihe open air the bet:te. The diet for the first day or day antl a half may ensist of fariinaecoits articles andtl beef-tea, but after this, should bIl generotuis, and nearly that to whlich he is. accu tt(iomed. I genetral'(allyt a liister acolnite for thirty-six hours or mi re after the op (eration. If Ithere is mot pain o(i especi"al disconiforti. t is est not to examine t(:.he eye by open-, - iln thlte lids dturitng' the first five or six da.s. If the ieve is quite hot an(ld ptainful during t#.he first few thours after t lie extractliol, cotld compresses may be Iused..f. (or t}he lirtsto forty-cigt lhours if the lpxain is sevelre, ad tlhe evelids swollen witth imuco-)urulent (lisfhatrge, we have al dahnmgerous comlplicat ioin, suppuratioin I'f the cornea. A. comnttress bandage is to be applied (, amd t (ll case trea:ted as described undter Suptpurative Cornrit is and Ophthatl-i A.FT E l TRUE ATMENT IN EXTiACT ION.'24: 7 miti s. i'.his co(-iplicat ion avoided, we may h.ave an acute iretis. AtiAropile shlould be instilled t into the ee at ncrCe, of the stireitgth of four gr airts or more t t:te ounttee of water, not only for the purpose of sCecuriln im1mtobility t tho te iris, but to prevent, if potssible, closure o the pupil. Thle advelnt of acute iritis may be known by pain, photophob1}: (ia, lachrytination, cheltmosis, (tiscolorattiont of the iris, turbid laqueftous hum1X:lor, and contlracted pupil. 1The treat'tI(enmt of iriti has s been already given,. Simtple iritis, of a serous cha ract:er, may conme on later from'(. irritation of the iris, and is less dangeroust ttn tlthe mntore rare acute sctelppturative or trailt-ntic iritis above timent iolned. Prolsapse the iris is liable to oc(urv soro0 ater extrat.ctionll in which case attopine and the:bandage are to be imnnmediatety applied. In case of corneal Jfist!a from imp.'erlfect union of the lips of the (w und, the edges of the orifice tmay be toucht1ed catt tiously with a solt.tion of ni ratofnitrat silver which. may effct thlte lCaling thlrough the local infl:ammnination set tup by it. If this fail, al iridectn:oy to relie ve intra-ocular pre ssur e could be tried. (fstoid c/if:tri:x, the namle given by Von (r-lfe to healing of the wound in the sclera or limbus cortnea? t:ttroutghll the intervent\ion of cic.atricial tissue which fintally becomes liniin and bulg'ing, is noticed oftenest asu a s3(equel of irid|ectotImy for gglautcoma. It may occur also) iin gttlaucomattous eyes, after extract-ion. We cannot chltange tlhec nature of the cicatrix, but we mlay perhtaps prevent, an increase of bulgitn, sometrimes, by orperating to remove int ra-ocular pirecssurc. 248 TIlE CRYlSTALIAN. LENS. CAPSULAR OPACITIES AFTIER EXTRACTION, After fullyt dilating the pupil with at ropine, the wrinkled, setli-opaqueti capsI)ul wlnichl some timles r clains int tle tpu)illary areat is to be torn open Iunder cocaine with. lainle dle wich is passed i is p nto the eve tlhrougl the cornea. See page250. It may he necessart to use two needles, one in each lthand, enitered at o))pposite sides of the corinea; their' poilts meeting inl the ca)psulec ctan )he moved in oppo)site direct ions, wvhich renders the division of it easier and more certain. In solnme instaitces, if the lmembrane is dense1 ( it.may he divided br a very narrowv knife whlich is madt e to -elter tlhe tiaterior chamtbet r at the outer or inn(-er edge( of the co-. ilca; sometilmes it; may be advisable to a.ttemtttlt thle withdriawal of the tough capsule by mieans of lt>he tdelicate canutlar l force)ps. i t is a hazLrdous plroceedingl, andx I have often klnown it to fail. None of these operations should be unde t rtakel un uti all irlrit iital t.y of the iris lis p)tassed away, and after the operation, altrtopinet should: e),. instilled, and the patient k;ept tfor ttwenty-fottr thouIrs ill a. sub:dued light. A. concentrated artificial light is very ser vieable in these delicate manwuvres. SECONI)A RY CATARACT is atn opacity of the s occurring in tihe comrse of glaucoma an:d other deep-seated disetases of the eye. \As a rule, nto operat iou for the retmoval: of the cat:a. iact is indicated, as tlte risk is veiry great:, without a prospect of correspoinding benefit. The operationt o)f 1mine, following tan iridecto' lyi for glaucolmal published iin the SOFT CATAh:UAC-t. 24 9 "New lEnrgland Medical C(azette " for June, 1869, was unusually successful, more so 0peCrhalps than could have rea'onalt.)ly been hopel d for. In' tlhalt case, however, there were pretty certa in indications thatt the ftundus of the eye tlhad been restored to a tolerably htaltht: conditilon. T'hie ptaticnti t c ould see a, lighted candtle in a datri k ene(l room!| at (1 distance of fifteen feet. T' there was evidelnce tha that tl glauconlma had l cettasd to progrecss, and there wtas a clhnelt t.hat whatevert i nmplrovei^ nt of sight, -milgt he g:aitnd bt y the remnoval of the tiaqtcu lens would be permanent, SOFT CATARIACT occur8s in children and in subjecets under thirty-five or fortrt yearsos of age. Its color andi glenetral applttearance have already bceen noticed. One of the conmr::tone)st folrms of thils lenItihculat op:iacity is the.ttfantilt or conteritai cataract.t /, It is either congenital, or develops duringl infancy. ""f.There( are two varicties: the lafmellar, called by ( eemant writers s/iei./,tstatar is a central optacity surroliuded I}) a more or less t'ransparent zone of lens sutbstance, so flinat when the putpil is fully dilated, the sight is usually illmprov:ed to a( reCmark-able de(grt(e. See Fig'S. 68, on the next lpage. It seemst to be connectled in some mlanner w\ith infantile convulsions. T}the p)rog.treyss of the opacity is slow, sometimes almost impel:)rceptibly so. (Chiltdren wit th}is form of cataat are often thotuglt to hte neatrt'-sighlted. thllt1s idt(ea maly be, corrc(cted 1ft the test mention(ed untder Amblolia, and t he cataract diagnosed 1)y ltatterl illlin'lattion or tthe ophthalm(scopc. t'he otlher variety of optacity, the cortictal cataract, is much '250 tTEB CRYSTALIANE iENS, lmore rapid il its courtlse. lThis op)-acity i's s8cet ill the form of opaquet sthi rutnning fro lthe tircCttlunfrene to the celntre, tt e ie illsteices at filrst showingl tralnslarenlt lens, whicth after a time beconies mottled, hazy, and opaque. 3 2! 4 F>. G ltefereces as Wfr.ore (Fig. 58) for l, 2, 8. In', the pupil is unditated, (After Nettleship,) When mature, the catariact is bluish-white, 1tnrcl dtense at thlce cent:re, tle striae often >present-ingh a pearly aspect. In ilnfantile cataractt n early Olperat-iolt is ilndicated in order to prevent, as far as possible, the ainblyopia retina, a which develops rapidly in young eyes, when tle visual rays of ligaht are excluded by opacitics in the t:ransparent media. )OPmtEATIONS FOR. SOFT CATAR 1 ACT i1ti, operattiotns for soft cataract atrc tl hoso of desisci sio'n, hnear e:l'.tr ction., t'- and st ion. D1 ei ssiot,, or 1solu:tion, consists in mi:ering telc eve tlhrough th e cornea with a: fin needle, ruptutring t "he capsulc of fthe lens centrally, and lacerating mor e oor l ess the lens 1su stancet, permittint g its absorption by the aqueous humt or, ~~~~~~~~~~~~~~ F z i- I. ~~~f; ~~7 ul ~~r~, _ * cu Cr ~ c "~i _l _rr _ _r,,, s- _3 -R -' 442 S-_ o 5 C -, - -4 - _ -4 ~ ~ ~ ~ ~ ~ ~ ~ ~~~t - =~ 2.. - 2 - _-,- 2 o, 5 —-~~~~~~ S;>Ck z( -,2; S=_ ~~~ Z a _O X -4- -4 - c~~~~~~ ~~~: - -, - -4- * XA~3> _ - _it \ - -_ - fr -4 c - _ _ H _ - - X * -, - _# i _Rt-,^ *S z - - l*"~~~.r. H;_, cR r,a _ a i _ r 11 h ~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~C Cj ~ *-4~' - - 4v - I- —' -" C) -4- -jr 3 -Ct - -,, ** C:e CZ tC - *- t C*R~.r rc~~ ~ ~ ~~-, _ " iSK jr rm, s J R: c~c C i 52 1THE, CR(iYSTALLIN.E LExNS. divin:- oaf the substane of the lens is mlore tharaugh 11an1d (?extende(d thlan ill tlhe ole advised for dise. ion and rem o fa the catartact b absori ption. Whent the l ens matter las bccome soft(ened and sw ollen bv admixture with lthe aqt(.eos humlor, the pupil being widoly dilated bv at ro.pi ln, and the eye rendeored amIesthetic by a i: saolution n lo. co) ain.. the corinett is op..ened at its temporat margin with a trl:ad needle in all oblique directi(on, A. cur~ette is then introduced the eve being fixed in the.most cnvlenienl t p(: osit ionl wit h th1e foreps), aind by gentle pressur:e uponl thil s f te lips ofn the wond, the selli-tlui lens wNill flow gentlvy down th ge groove tf the curette.: and b bronuigh t o't att the small cort)eal aperture. A ftertards the silmnplie Ilandagce shaould be app)lied, and the padient kept in bed fJor twent y-fouIl hours, the: pupil being dilted by atrpin applied t daily, ut1 i all si gns of irit...is lik\e the linear, is probably more easily e amplished a few days after breakin I g Ip the lens w ith the needle. although either operation may fI low iinmediately, if neeessary. iThe operation is like the last; described, only in place of the ordinary Ncrette, is substituted a tubulmair one, attaehed to a seeond tumlbet ( If glass, and timis to a metal svringfe from which the suction power i ohtained.,'Thel syringTe is conlstrncted so as to be worked iby the right hand, which also guides the e(nrette, while the lhft keeps the eye in position by the forceps. Diabdtbc earaot, appearingin the course of a. diabetes, is generally soft, but harder in elderly persons. ' CASI.k ULAYt CATA IAC, C253 It is to be reimnoved bv extract ion, if the health of the patient is not too much impaired. I have opera eld d0i cessulir ill s Ch Cases, when the patient has had no prospect of living, beyond a few mont}hs, i catarac:'t is of'ire oet' urct ie e. Ge eral- v the re is a nucleus l oreS orl less ftirm. Suetion, or linear tractio, is the( suitable operation for it. I appearace, it is mtilky-white, lihomogteneous, and without opaleseeint striipes. MED)ICAL. TRirATMENT OF CATAIRACT', ataract{ is mknown to be a result of e'rgotisin. It as also been produced in frogs by radministeringx su^ar in lar l quanltities, or by i i t unde.r the skin rid S oft sodium-t and alcohol have producede simlar reslo ts. In 0our school, cures, or beneficial results, are reported to have fo1vled the use of cannabis coniuin, phjospliorus, and many other remedies int ernallr. There are reports also of cures~ by galvanisin elect'ieity, anid massage of the eve. But senile cataract is culrable in one way onlyv; namely, by the removal of the Opaqutiie lens fromn the visual field through a surgical operation. (See cause of senile cataract, pages 238, 240), CAPSULAR CATRAA.CT. Ante(crior'sap's'u tar cataract or 0anteri or polar cata rae, is usually situated centrally, and is caused originally by an inflammation of the iris or' cornea. In young children the anterior chamber is verr shallow, and in the new-born it scarcely exists at all, the comnea and lens being nearly in contact, so that an opihthalmia 254 TIHE CRYSTALINE LENS. would he likely to extendt to the cap, o i pu leave some deposit upon its anterior surface. Tis condition sometiles gives rise to a form of cataract called pyramidal: it: projects into the pup1, but is within the capsule of the lens. An art icial pupil is all indicated in this form of opacity. In capshiventic cataact, both capsuio and lens are extracted either separately or together. DIISLOCATION OF Tit LENS may be spontaneous, the result of a blow on the eve or head, or it may be) congenital and hereditar. It is either partial or complete. The lens mav be thrown backwward into the vitreous humor, forward through the pupil into the anterior chamber, or by a rupture of the sclerotic it mar be forced beneath the conjunctivaha.I the latter case, and also when dislocated into the anterior chamber, it should be extracted. If lying in the vitreous it may be permitte d to remain, if its presence occasions no irtation, if otherwise, it should be extracted. iDlAON)5JOSi. There is generally pail, photophoina, lachrvmation, tremulousness of the iris, and the signs of absence of the lens behind the pupil, mentioned under Aphakia. Lyintg in the aniterior ciauber, the lens mnay be plainly seen and recognized. Not long since, however, a case was sent me which had been called an opacity of the cornea. It was in ai eye otherwise diseased, and the dislocation was occasioned by a blow on the head. TiAU MATIC CATARACT. 255 UlJiler the colijulnctiva, the d.islplaced lens mnay be seen a it parent swe.lling. In pa rtial dislocations there will boh)e monocular diplopia. or pol)opia. Lateral ilium atiOt wAill etilnable us to deterl'mine the namount, of (dis}platcemnenlt. Direct exami'nation with the ophthalmoscope is still better. We may thell see the free edge olf the leans as a dark creseentic line 1across lthe red pupil. Partii~al dispilacimelnt often causes great. irritaition and nmay lead. to glaucomatous it'flamniation; in tsuclh cases the len-'s'is to be extracted. Someltimlles the great irritat~ion experienced at first miav be lessened bh the instillation of cocaine, atropine, by warm soothling" foment at ions of belladonna, ehamomilla, opium, and the internal administration of indicated remedies. in congenital 1or other cases', where the dislocation aljppea rs fixed, an operation for artiticial pupil is indicated, TRAiUMATIC CATARACT. The opacit' in the lens generally commences within twxxentvyfoonr bours after the injury to the capsunle. -It is at first confined to the locality of the wound, but soon. involves the cutire lens, spreading more rapidly, the younger the subject. There may be considerable pain and irritation mrcsulting from the wound in the cornea, or laceration of the iris, or simply from the pressuriie of the swollen lens upon the iris. Traumatic cataract may occur from a blow, which, without the rupture of the external tunics of the eye, may nevertheless rend tlih capsule of the lens. The puplil should be kept dilated, and the treatment be, siimilar to that mentioned in dislocation of the lens. After the irritation has sub 27546 TH1'1Il E C MRYSTALLINE.1I ENS, sided1 if the absorptioll of the len s is found to bo on, there s8hlouldl b!le no surgical interference; but if the pain l continues, t ension of t lobe tis increased the pinkish zone around the l)order is marked, and traw matic glaucomna is feared, the les should be extracted. APHAKIA, 1or abseIWin of the crystalline Iles, occurs after extracti on, from conmplete dislocation, aInd after ahsorption of the lens. It may eb recogunized when the histonr of the case is not known, by the blackness of the pupil, di minishied size of the anterior chamber, awl tromulousness of the iris in case the latter lias lost the support of the capsule also. TPhe refraction of the eye is, of course, much changed. An emimetropic eye becomes hypermet ropi c, a hypermetropie eve more hypermitropic, a myopic eye less myo}ic, and the power of accommodation is gone. T1hle spectacles suited to this condition of the eye are spoken of in the next chapter. SPEC,(T AC.LE,/ i]aS ~..1 A (TIFICIA ES.Y E. ]Y. SPEC('TACLES. THE otdill:na.y l,.Isses fo sjl, sectales, in opt idef..a t, are covivex or eoa ve,. p/eerilt except: i n asti iiga i ia'ewhen hev ar'e c/el'!ri! or a co,' nationmt) ot h spj heoi al and cyvlinadrical, in nuisntlar isuthc ieneiCs ey aIrc i'Tisms, eitheir alone or iI nComlbinatio: wvith thi othlers. The nature and use of tlhese'glasses have alreadv wbeen,s'ticientilv expldailned. power of the eve is lost, and therefore two 1pa10 ot spectaele iisi he nIecessa rv, onw for rending', of albout 1two and one-half inches torus, and the otler tour and one-half inche:s focus for d(ista1nce. Thltese nuiner ill varv oinewhat accordin gt to the retractive sate of the eve before operating whether emnet ropic, myopic, ort hperctropic. It. is (advised bv sonc surgeons th3at thTIe.lasssES 1s1(1hould 1 ehi 1)-1 1s'tm' Id la circl',ed b 1} black'ri:: of ebo: i V} or shell a quarter of an IIin in width. Large glhsses admit too IIIuch li t into the eye, and enuse a dazzling se(sation. Somnetnies a combination of cylin.ndrieal with 17 258 SPECTACILES AT. CIA. BY S.T tlh spherical glasses is required lit order to afford suiweient ac'tteness of vision for the patient to read ith comfort. Cataract glasses should not Ae worn for some weeks aft ter the operation; while.much irritation remais it is better not to attempt the use of the eves for near objects. PANTOSCOPIC LA verres dti doul. e er, are sometes called n in glasses from the fact that he wore such. The upper aid lower half of each glass have different foci. If a inyope becomes presbyopic, the upper half of Inis glasses would bel conca-ve for distance, and the lower half convex, to neutralize his presbyopia in reading. PRiISMATIC AND DECTIKIE) CLASSES, Prismatic glasses are useful in aiding or exercising certain muscles of the eve, as explained under Muscular insulfhciencies and thlie article on Stab is)us. Decentred lenses are so constructed that the weaurer looks through an eccentric part instead of the centre. A convex lens, for instance, may he so arranged that its centre lies a little to the inner side of the visual axis, in consequence of which a slight effect of a priismn is produced. EYA' PRtOThCTORiS. Eye protectors made of eurved glass are the best. Goggles with l ive, silk, or glass sides keep the eye, as a general rule, too (lose and warm. For photophobin, simnple colored spectacles of plain glass are suf.lcient, and may be d(arker or lighter in shade, according to the amount of protection required. ARTIFICIAL EYES. 259 Strong plate-glass speetacles are worn by those finding it necessary to protect the eyes against chips and partieles of stone or steel. It is proposed to make them of curved mica. Such spectacles would be cliheap, durable, not likely to break, and very light. STENOPAIC SPECTACLES, comp)osed of mnetallic plates with small' central apertures, are useful in opacities or cloudiness of the corliea. They exclude the peripheral, and permit onlly the central rays of light to enter fthe eye' acuteness of vision for ne(ar objects is increased, but fltheyv are not se.. viceable for more disttant views, as they limit the field of vision too much. ARTIFICIAL EYES. After enueleation or excision of the eyeball, or after excision of a sttaphyloma. t of the cornea, or ill case of a shlrunken globe froml any operative interference or disease, Ithe deformity may be almost completely removed )by wea ring a suitable artificial eye. 1.t should not be wtor steadily for a month or six weeks after the removal of tthe eyeball, lest irritation and intfltammatiiol of the conjunctiivat% ensue. To ilsert it, lthe upper lid is to )be raised, the upper border of the artificial eye introdtcced beneath it, and the lid allowed to fall; then tlte loweri lid is to be depressed and gently pulled forward, when the artificial eye will slip into place. To remove it, depress the lower lid, and with a hook or bodkin force its lower edge forward, and it will fal'out. It should be caught o(il something soft or yieldig so as not :1" ^ "^ ^ ^ ^ ~~-^ % ^ -.-. -* y; - X S 1*,_ 4; - r \\|': - - jog_ o;,... -. Ax -Z: DIOPTR IC SYSTREIM ^I NUM/vtRATION { () t LI NSES.:261. Numbenrs in Focal distance. (TCorrei>Soul:in ol d iolp —Itricrsi' Paris inches. numbers (ntcarly). 1I....... ^.".,... s.,....,9'.).. 120....,... will bhe noticed th/at the tnumber of the leu Ts inl the new svstem d oe s not corresponl1d, as in tle. old systelm, to its focal lensth; hbut in order t.o find the focal lenlgth, we of 9 inches; or, if we all the metre 410 inctes (a metre is 89.T EtInuglsh inches), a lens of 4 diotptrics is one5 iot:10 Eglish inehes focal length,. To te~st tlhe, visual power, under t:his systems, we 1tt:place before the patijent at a distance of six met res ( about Itwenty feet~letters of the sie of those numbered c 0 in the second series of test type annexed to this volume. If lie distinguishes these letters easily at six metres' his vis in, is S or one. 11 he can 0l1 see larger letters iperihaps those numbered TO, a six metires dist ace, his V.,'very nearly, the sevenity feet beia g about In1 a case of amnetropia, take a convex lens of one dioptric (1) I 1 If distat vision is impiroved oP iim - paired by it, there is a mnanmifest Ivpcrmetrop fa of 0., dioptrTic. 1f, in anuot her case, vision is most inmproved by 1) ~a4, there is a myopia of four diopt rirs. 262 SPECTACtES A. TI1T HO!AL EYES. To tcst the range or power of accommlodation. in the elmmettropic eye, the nearest point at which vision is most distinct for small objects (the fimest type) gives the mcasure of the accommodative l)ower. For exampie, suppose this point; to be one linth of a metre from the eye, then fTour dioptrics would express the range of accommodation, the far poin:lt being infiniteit distance. ThIle accommodative effort lirought i into service to see at thllis distance equals the effect of a convex lens of four dioptrics, if such a lens could be placed with in the eve, The same method is available in a case of hiyperncmetropia or presbyopia, the optical defe.t being Ji rst corrected by a proper lens. I!n a case of myopia, say of three dioptricss, - that. is, the far' poinlt is twelve itches, and the near loint at three ill nches, thel ac onnodat..iv. range is then from three to t:twe lve dioptlrics th:at is, it it equals nilne diopt:rics. Practtically, lowever, in hy llpermetopia, I prefer to test the range of accommodation by fitting proper g'lasses for reading, ald thenlt n(oting the far and near points thus yesterday, (for a yvotng, mat of eitlteen years, with slight; manifest1 hype etropia, I 1resentedf ))..- for read ing. With these glasses lie could read No. I type at tlirteen. centi. metres and t fortyselven c( nt:i:res (from five and on e-fourth intc ic1es iup to eighteen and one-half inches), a. very good power of accomntmodat0ioni..ll the ease oft a, wom(an of sixty, both iyvpermeti.rop tic and presbyopic, throug'h grlasses of three dioptl)rics she could read the tfincst ty]pe froln twenity.4-tree centim etres to fort(y-four ce'ttimetress; also a fair power of accoummodation for her age. CHI'I A.PTE XIV. THE MUSCLES OF THE EYE. PARALYSI8, "I!l nerves supplying the muscles of the eve are the third (oculo-1uoutoruis), fourth (t rochlcar), and si xt.lt (abdlicens). The third supplies the internal, s5uperior, iand inferior recti, the inferior oblique, the l'vator palpeibr'superioris, thle constrictor pupill',) and. the ciliary tmuscle,. The fourtt. nerve supplies the superior obiltique, and the sixth t'he external rectus. The rectus extermus moves the eve out.ward. i; iinterulls Imoves the eye inward,'* +' " supirior mloves the eye upward and inward, and rolls (inelhesi the vertical meridian) tlhe. eye inward. " " inferior imoves the eye downward tand inward, and rolls it outward. superior oblique moves the eve downwardi and ouitwardand rolls it inward. "inferior oblique moves the eve upward. and outward, and rolls it outward. The third and sixth nerves are m(-)ore) often affectit ted, the fourth vc rya rearly. ] or c)onvei en) in deserit ing the diagn:)ostic symptoms, we will consider the paralytic afetion as occurring in I: the le ft eye. 264: THEt t I U'SCIX S ( OiF TiffOE EY I'. PA tA XLYSIS'i'0 ll X tX {.XT lJ NL iltCT(.{J; ()n mol(vingl ai tlo (}-tject t)f(t) e( tlt'e t(-y fr'oit rig'lt to left (a lig'hted catndle is cont.venllint), fa convergc. —nt squlint is nottticed. TIe m ove(ment of t he eve to t he lieft is slttg gbisHtl.'Thcere is diploptia as tthe oj}eci(Vt is:tmove: d int-o tlhe left ha1lf::t of the field oi: visio, thto imittages beinl-lg loiit tolti'ym n(s (noti cro(ssed, the tria'gt belonlglitgi to ithe- rig- t ('9 t.:fl'ft. lef; tO; f thi le ft cve), iara'tlle l, of thei stt.ame Iheig.h t, I tit distailct'. c -et:w(.ni the.t'm iln - _ rea si g as ti he object is lmoved l arthler to the left.'Ihe position of thie headt is also ( chatiact-erist ic, the patiecnt carryin ig it; itiitned sominevhaiin t to lthe lefti, int order to avoid tlihe conifusion of sightt atisit(g f ]roli the double) iintaers. A. prisnmat:ic g"lass nnmav he NV. wo'n I;t) corre ct tlhe di plo)pita, -as slhown ini Fig. 69.:'m. iD.. A-i pr.ism entIs tile rays of Tlhis igulr, frou N ettieshl i, i r i is t hows how a pI I m ta m I | gu t.OWIXiS ri ts laSC.. pp tiiplopia, It (the right eye) is ti i it rtei. ltowards eri' stead oft ob (the ie "et objea:), andt two imavgezs lof ob are _jO, miitwoi'e',ofro: t ardts the tenlple, rays of seen. It.he prism p, before the right pry deili^eo the raIs to Ii:ht art I ten, t iouit ward, a nd!1 (the yellow spot), anud single vKision:s thle 1'. in thti t lnllt age is ir'ojectd isnward'I thte right eve i: stUppo-ed to he,,,1, t.' a-itfictrlu' I:rlto a s that oi the otfher evye. ThIe piist nati c glass sh ( Id I')e just s'ti'rotn enough to: fu t se the two i ages. If we wish tto cxCtci' thie ftl. iparaly z rectu: so as gi traduall o t'o s{:trenti}e: it, we may prescrit e reetus so as i'ng hen- to str}}-t j9 it, \~'t' nItty [It'f5i' i1CS, PA.tHA'iiYSS (.OF TitCl'; SU:PEI.It:IN 0IA. 2(6 ia weaker lprismitiatic glass l I whiclti dtoes not qutite fuse, but ai.)lr',i'O xiates very nearly the t: wot ilnages. Te e fort of the eve to fultse th11 itlltgts will call the trecet:lus eXxttertus into aettion to( a liltited ext:ent:, and as it Ogrows stirogcer (we may weaken tnhe prismt s. PARAlt.,YSI OF TtIC INTENRNAl, t IC[tltUS is rarely.vmet: wit t as tan isolated a clecti n.'The t hi rd ltneve supplying rralso t1 h Sup'eritor and it fetrior rectti, the: inferior obllique ant: d otherls, severl. lmuscles aret simu itanteo nitsl aftt'cft:te The sympttoms two(tltt, how\eve r, be the reverse of thtose, jst noti(':ed, and prismalttic glasses would he worn with lthe ase i ward. Tei.. )patient.l would also incline his he. ad slightly tor tow'a:rds the righit. In iA HA L.YSl S OF T i /t SI UPEI iOit l i CT I. tS, th(e. eve will not; t lurn upward readily. T..c.re is also a slight diverg)'ent squinti. Tl.he( inferior oblique drawintt the( eve 1outward. crot'ssed dot0)ile imaltges will otcurtl in the utppelr half ofti t Ihe visual fieldt. Thel imag(es ar(e not p;arallel, d i verg upward, and differ i i l heig t:. PA I ALYSIS OF S TS E ( INlEURIOit iHECtYIUTS would. occasion sympto ms j1 st the re verse of the a ove. i n1. )PA I. A, YS, O TE I SU t' IO O BL. I' QUE) ti the deviation of the visual ax is is very stightt. There is a want of mobility notict:ed in the attemplt to turn:. the tev( d(ttIownward and! itward. Iolmt: onymous, or cor-tresplondiing d(oublei nmages are seen in the lowerr half | t i~s}t~ll01 il brXi{}~l} lit l 17~t4218 (li~ 234>>^*8. lll t}l{} | ltrtll 1}*_ | 2t(G TiiE IMU t'SCAS OF1 TlH EY E, (of the field of visi:on.'Ile left limag (that of the aftected eve) tappears lower than the other. The imatges will hbe obliql1ti, (:onive1rgi' g towar.ds tlhe top..Thelc patient lwibll he a 1tnnoye in descending stkairs, whIich aptpearl dolic:te and itrretgular in outlin ll. H ol will be arpt to tu:rnt his head do'wnward and to the right, so as to lbrinlg objecdts into thle upper and left portion of the field of visioln, avoidinlg the (liplopia, P'aralysis of tit inferior oblique alonte almlost never occurs PA AIi YSit Oft T.f1E- THI. t) NElXRVFI Int. a lhe co n')lcete, afficctinlg all the muscles suplplied by it, or it maly be pa -1rtial, affect:ing 01onl one or n1more of the nnittlsc.cs..11n om.'ple.t:t aralvsis, say of (the left eye, tlhere is fitrst ptosis. Otn:rais ing lthe ut t lter lid woe filnd telt eve'tstrict.ed it its mlovteents in the upwarttd, tdownwal d, andll inlward directiols.'Tle'rctu:ts extciritIs, )e}ing su}pplied Iby the sixth. ntervet, is utatffeettd, anl the (t'e ey ca cot( tsquc ntly itmoe oult\att'd. It; can 1also miove to a ce'tat i ext:ent dowinwi' ard and outward, tlhrou( gh tihe stl.pe tio''l' ('t)bliiqute, wt'I-ich. is stt'li(t 1ic tt: l-cI fo ti t.'t:Ei t e.i'vc..'1rognftosis (tand ireattmentt. \'Wh'lethet a curtc f pa'ralysis of t:hel i muscles of tlhe eye can he progi)osi('d, defpentIds chiefly uf m'n. t -he case of fthe. afftctio,; or. wht) twlet hic lesi.on bie pIe'i tphe tc.al or c)ntr'al,. If syp7 h ilitic, ta nott tIotun uo(.mnot cattsea, the p'rotgtlosis is gener:i.t'tally fa.vot.ablce, tht(e lcs sion bein g tusuat ll petriphleral. If o.f'rheIuitt ati'( trigi, t}che pr'ogno:sis is highltv favorablte'tlht l l. lien due to i int:t': racramial causes(t, o) XPARALYSIS OF THiE TH1111R1) NERVE, 267 sev.erle injury, fte prognosis is, of course, often infavorable. Thle more acute the case, generally speaiking, thle better are the chainces for a cure. In syphilitic cases, I believe iodide of potatsh, after Imrctt u, t:o be the best remedy. In rhel uatic ctases, wlhere tihe sealt of the disease is probably the sheath of tite nerve, my experience hlas beenl excellent wiith bryonia, gelsemiturm, lmerculry. Local treatment should not be ineglected. Passive lttovtlnemTlts of th eye vshould be made by seizing the c.onjiunctival with the forceps and rota;ttinlt it sever1al times in 1successi ( lon towards the a:ffected muscle.'T.lhis can1 b e done aily under cocaine. The patient. sthould also 3exerteise the eye by efforts to roll it towards the weancketCed tt.mulscle.'ThLe chlatltces o~f culre ae mlttcht incretascedI if the paralysis is partial Ilandt only one nerve talte (. cteid, thle genralt nel\rvlous svsttem beilng in good condition. in case of ptaralytsis of the sixth} nerve (externalt irctois), tlie condit ion of the abdomtinal viscera should receive more than ordinary attention, as tlis nerve seems to be partl'tictarlty influenced by reflex action fromi the synmipatbtict. W\hen otltcr means fail, patrlysis of the c uila.t muscles front perih'lewral'or Oxtratrainial catuses matt sometimes be cured by electricity, Faradi zationt doesc not appear to be as eletiacious as the primt ary gtal vani currentl Painl int tithe head, dizzilnss, loss of intelle:(ctual power, lunsteady imov'emn. lt ts, a nd great; dific(lIte y in fusing thet' doublle images by prisms, tal indicate a cere bral (caltse. A\lmont^ the cerebral lesions.mavy:e me: ntionedt ttubercutar deposits, hydrocephalus, Cflusionls ot b)l(o:od, allecurisims, softcting (rillf the b1ra in, and Itumors. tstti ts 268'IIIlt: MUSCLES 0ti-' THIE It Yx i. pit^rio sit is, es tos is, and ttt the o /aise s' of the braI in sitmt ti t t es oc a ion tl h paralysis. HSim i ai r orti:ail ttl.'e.tiols 1 n Ist cV a118 caut it It1 c(hltdretl, ofteite 1.1 th1an in a(dutlts, aI local pa al. y sis 1ayt t be thllie 1'l t11: t of somt n8 ervos iriitat'ion ini a. dist8ailt i)al'H'. IDentitio l is o'ft e:n the.exe itin c aus 1i a1td it n si'li i sta (-.es5 tl1e i)r gtl sis is n' l. Vi ltw s f!'ttOav''orat ble. is relieved.\ ty:i ) ta.dag:i l one (: ye or i vy th e s e of spect X.lat' ter l. w otielr r edia11 11easi uret 1s fatil, tor oatl t p: ar i ialltv c.oipI('le1't t: tie (rel, tie' ati ( in al di t'irection of the eye antd thet.. resultilg diptli ltia may sot m'i1ttimes I(t'tremtedie d Iy an o )pera tio)t 4 (1 to rest ore thie ei tiuilii trii of the 11n l.a cles. TI is w(o)uld consist i.' Io ta)ly t o I a tte not. ofs thie opjo ipsipug, 1n1 1 al1 d lva ncneentien of' th1 wedake:e-t, t. siletc. T'l'., d(esct'riti' on (i of. )t. pera'tins:on thie ntust(le's of tlh eveh )all is,iv ven uIett r I( 1 l tlh'artii le ve're lt:ve rils anld t debilit:atit.g' dtise(ases like dii phthe t ia. I(t mav ble tI:produ c''Id tempo101l)rarily 1 v 1 dropptliiig, a mtydryat:ic, like at:opiue, into the eye. The latiel t sees well at ta distaltnc, lu(t: its 1:it:, aIftle( t read' tie tprin t. Nelal obj(ficts apll:)ear' i 1(1istinct. Suitaile convex glasses will restore netar visi(on. Perfect rest. of then eves and ft''eqnent 1.adlthing iun cold 8THA'itMl U IS U 269 watelr should be enjoiined. Th'e bdiet: iln theCe eases ouight: to be gelerous altd Ilitiut 1 anad hvytieiiie:; eoditioiis. slhA1ld( he madb e ad s a fvorable as possibde, lienItedies tadapted to the ilpovcerished eondition of the patient s svstom Inmay be useitd, bliut ime alonel will also (ctr1 the a freet oim., TiNSIOlN O)i T'lE ILLIA Y MiUS CI.T is iiet with in hIvIper.retiro(j i a as well as 11 in lyVopia. Itt o(easi ons niyo )pic refraction of the eye, so that tlhe patt'ient sees better iln the d(istalnce through conlteaveC glhasses. 1.-y t' ral vzin' the eiliar'V musele holi\ev,'er, we linid tl0at tIhe eye is really lpv ilernmietro:pic'; the 1tenlsion.ppe'ars to b.e the mresult: of overworkin ng' tIhe oilia ry muscle in aco.oimodatig, or 1'ma' he due to great exIposure: of tlhe eves to brighilt litiht. B!est alone or rest-a nd at: ropine instillation are the remed ies; late. r, 1the: faultxl rebtf1action shoutld bre c'orected by pr'opt:'e glasses..i'nstt;us, or involuttntary oseillati on ol tleI e yeb iall, is owiniig to spqasmodici twvitelit:ng' of the nmuseles w! v ich conttrol hlie trlobe. It is most frequ'(IentiI see in eongenital cataract in eh ildren, but n0may 1)c4 brougtiht oim b1) ~an.y a.f[fectioU of the eye wvhich c0aus.s idlisti tneiess ofi vision,. It s eure can only lbe effeet ed by restor'ingmt autieII(ss( of vis1ion to the diseased eve. sTi A uIs Itus (CONCOMITANT STA!I i3M S). lyx this termn is mea.nt a manifest deviation of the opti:: axes; latent or ('dynamici squint is notieed el.sewl.here, When the eye is turned inxtward it is t:ermeld eo.vergoent s'tiabtismus; if outward, dive'erqet s'tral mis us. If eonlined to one eve. it is ca'lled:mnot'uh/r; if the squint alternates 270'HtIE M3USCLES OF THE EYE, between the two eyes, it is bintocltt or alternatiqj strabism tus. Il the latter case, tihe a(cutelness of visionl in the ttwo eyes being about the same, the patient fixes somctimnes one e.ye sometimles the other; on the object, the squinting eye being the olne not il use for the time }being.:tIn inonoel')t lar strabismius the sight; of the squinting eye is alhnost invariably impaired, and no attempt is matde by the patient to use it. IInt treatmentl it is practical to divide strabismius also into th per iodi and the e t cof/tlirmt:cd, although tthe pathology of the two is usually identtical, and lthe first is but the p;recursor of the second. Occasionally, however, we meet; w\ith a- periodi(c squint, estecially in children, whe\re ttm affect1ion may be tr t::td t: l s tome nervous irrtitation in a distant part, or to the ce(trebral itlritatiot ft1trom dlentitiont. No doubt that a S(lqint of 0 tis kindl arises often fro)m pa(rtial pitaralysis of one or more of the ocuilar mus.cless, andt is therefore not 1pro pe)rl( y spoken of under the head of tConcomitant; Str ablisus. In the latter t'here is a tel:nsion os r ant increased energy or( shl()rteling l f a misc l lec, but.l the eyebal ll catn e m soved, although these ml(otions mttay be.) somewha(t restricted, outward or inward. at will, and in this it ( differs from partalytic stTabismus. "Th/e catuse of trabisnmus are errors of refraction, uniscular insuflicienc:ies, tiamb)lyopia, or anty ctonditionl tentding to inequalities of vision in the two eyes. CION'VxtIEG }NT STRtABISMUS is usually associated with hypermetropt)ia. onllers blelieved tthis to be the ease in sevenlty-seven per cent, and CON()N VItECRUG llENIT S S t.UA H::iSM tS. T, 27 1 I)o Weeker in eiglttv per cent,.It will be r emenic'eiered thatt in tho hvt)Cern l topic eye tle a ntero-iposterior diamneter is too shlort, alldl that paral'lel trays of lighlt reach fle: retina before bleing focussed1, and visiton i therefore inllistinctet thlat: thle rfcetfltacivye powerl ol such eyses re't (f uir cs to be aidedt bv ctnvex glasses in otrdr to prevent over-exertion in alcc tonf odatitng or accommodative asthc-'n(opia. I rtegardtin' near ohje;' ts, still,greater exert'iolns to") atccolmlodateo art'e necessaryt a! tlt ((co)lsenltlaneous withIt accomntt01dation- comes the conlverg'ttenc of the visual. axets in ord.er t:o fix both ecys on the same Ineat r t ntl. Convergence, however, il s tch eyes is gr eater thatt itnd er similtar circltmstanc(s i(t wouldtl e, inl normall v refractive (enllm et:roptic) eves. A habit of tiurIilag the et.ycs inwa iw s forlied, whltich results first'i in a l). priodic thean inl: a lpermanentltt squinti. Tl he c( on.vergtent e ei ig too great:, the child finlds it easier to see, if he t atrnll one eye slightly outward or fixes with one eyve the lfelow ye, foill owinglt the llmovementl t rolll s still fa rthler inwardl an.d thle h'abit of Squintilng' boegins. aSucth squintt often. makes its tsap:lpearan ce int childreln at the a ge of fourI five, orh six,>'calxs, whl t.ey are learn ing't i to retad altt is often attributed to:any cause but; the right tone,. Solmeti:es it..s its appa.' c is toticed a few year(:s latter when tlhe first.earest stsud is b. eg if o eve happels to b)e 1motref hyprmetrop.ic than t! o tlerl thee tn.dency to sq:uint, is still strt'onger; for this eye m1ay t.hen turn inwalrd without tle antlnoyaince which would ottherwise tbe occasioned bhy the producttion of distinct double visionl. The s:ame would be true i ifn ivpermectropia one eve should be am:blyopic or defective in visito 272'rII. M US'CL..EuS O8 ). TH.E ErYu, fromi o((acity of atily kilt i, or if th-e rccditts sextetus l be itt}stltal \ly weak.. t lrich, Seggrer and o thers have i sh(own tha t inl non- s('Ittllg })rn'lett:ttrop)ic eye(:s tlhe al:bdu:tion ic s stro:t)lger thioKt' iin emme(ttor(lpic eves; Ihen(' the reasonable infer-'cie tlhat: in sqtoinitinlg t.ev:s ass:oiat(ed w\ith hylperm'net'ro ptia. tile ab::duct ion is co.mtarativ ely weak. )I.1ts1.:iNt SPTtA tT I BIJl wS S is vetry apt, to 0 e associated wvith ilyoplia. iLarge Stial:)Iylollta. p})sti'uni-tl'l o' pst(ostriorl' btullging of the glot)e,( itci'nretases thei( ttende(ltc.yv otf thte mvopic: e ye to t:ullrn ou)tward, 1a5 does als'o) tihe freqruent; weakness in the internal ret-t ti miet with in liyop)ia (.)t actt.ount of dtie telon-.(gated shape o. the eyebtall it is dit. icult to (.conv(xert(,e to t'j t lhe..tar p)ointi fr tmyotl')i isit)l. T'ilherefore: o.e e is use:d tand tlhe. othe'r rolills outtward. (One ee(). bt-:t>,lt, ll iort: mt lopic than the (othrittl' i)ncretases the' t tledenlc to divertge(.nt strl: txisus. (':t, rtt r: it(.tet:.ts of sight in I'oth eyves, vi ion bteingl' altmost ablsent, are apt to) produce sitgltt:.ivergen.t sqiuiint.'TO DEI0EVTtMINE WIt1CQ11 E.YE I1 A IXFECT'ID), Let the pati:.entl re'gard an obl.je(^ <***~~ i v* ^*** -.0~ ~~~~~~~~- -a Co a~~~~~~~~~~~~~~~~~~~~~~~~~l 274'TlE MUSCLES T OF I'I FYE..Wv., while it is turned inward or outwar.d, and then covering the sound t ey permit the form-er to fix itself o11 SOtllc conlvelnient object, when a second ( ma1.111 tk 1t beneatl the cciti.rc of the pupil is agatin made.'Tle distance bet.ween the two imarks gives the extent of the strab is m nus. Several inmstrum':tents are inA vogue also for the imeasureimient of squint, but the above method is simlple and generally sufficientlyv exaet. See il"g 0 T.eatment. T he tfrcatmoent, of course, will depend vei.y nmuch upoll the cause, also utpo the history, d1uration, the state of vision, almou1nt of d(e.viation, peritodicity or permanency, and wtiether monocular or bilnocular. All these points are first to be invest igated, Wthen the. squint is recentt, and the result of nervous disturbance from asea.rides, dent.ition, whoopilng-cough, gast:ric or othler visceral affetetion, the removal of the pri(mary disease I by suit able general treatment, may restor the t eyves to their normal position. I have knowin squ iint to d isapp);tar spontaneous ly. I will not enutmerate the many internal remcdies accredited with the cure of this deformity, but:.1 may say that I onice. heard a. distinguished 1surgeon rCemark thalt forty per cent of the cases in youngI people get well by proper hygienic treatm.ent and a correctionil of their optical defect by suitable g'lasses. Not long ago a lady, upon whose daughiter I had op)erateid for sttraisn1us, informed me thlat: the reason she had not.. insisted on an earl. ier operation in the case of her dautghter was that she had herself been "1cross-eyed" at tlle age of seventeen, but S1$~~~~ -" -,~;,c~ Z3 j r -~ —. ~- -z z3- Zr~ *(* i's~~j u.i -C: c-Z -- - -r ~~~~~' 5- **rur= * -"~~~.5.. " 5-~ " Zr 0 u -. h - — 5 -t ( I - ~ ~ rr 4 ~~~~~~~~~~~~~~~~ ~ - c' " Z r ~rr h-: ~~~~ I ~~~ ~ ~ I 54~~ ~ ~ ~ ~ ~ ~ ~ - -r Zr - - 5 — l? -3 - ZrL A"-I -L_ c~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~c.1-~ ~ ~ ~~ 3" Y h ~~ py C --- - -"-c,- " r~rr~I "5 5- -5 -5 " 55 — i - ~ -51~t_ 0~~t ZrZ -Z -,- ~ rC - * -3 -.j 5- "5 - - -- ~~~~Z Zr Z Z Zr Zq~rr * r? 0s Zr" ~~i Y-? m ~-^-T C- 5-~ 1 i - -_ - _C-r.- 0 Zr' -Zr Zrr - - Zr' Zr Zri 27T6 TH.E MUSCLES OF TmU EYE. slt outwautard, Tli eve et is turned outward tlhrough tihe i voluntary effort; to fuse tlhe double images, care bein$g1~ tlak(en thlat the plrisnm be of just sufficient: strengt-h to n(eatly, but lnot quite, accomplishl tlte fusion, In Iorder t-o excrc(ise the internal rectus, the base of the prism. should be directed outward.'lThese orthopa:edic'asurelS will generally be flounld more efficacious in slitght paralytic than1 in conconmitantt squinLt In the latter, however, thevy may be used to ad(vantage,'when nece ssat'y, with at ropine, in perfecti lg the lresult of an operation, and especially in aiding to fuse the double images, which solnltimes are very annllovint aftr op erat ions. Bee g 69 Ut) on page 264. A naother method of treat inent; fa-vorably mentionled for conyverget it stTabismus witi hytpermetropia, in chtildr en is to paral ze the ciliart muscle with atropine, so as to prevent all attellmpt to accommodate, up to the time whenl suitable glasses ean be worn. Coimmenced early, during peri.. od ic squinat, this treatment has proved successful in some instances. u.rgical re.atrtient of,Strabismus. When the case is of long' standing the operation of tenotomy i isindicated, the object' being to divide thel shortened lmuscle at its insert'ion inl the sclerotic, and permit it to reattach itself farther back.'The operation which I usually performn, anfd which I think most advisable, is that of Volt (ra-te. The eyelids lhaving been separated by a speculum or an as"sistantt, supposi ng it a case of convertgent st ral ismius, the assistant turns the eve out.ward with a pair of for 4B ~p- 5* -s X; a c - - O,' ~ ~ ~' ~~ — ~ C I I -i M 1 -,C A~~~~ ~ 7 ~i:i 278 ~TiLE. MUSCLES OF TIlE EYE. tmay be applied over the losd lids, an a w doses of 4l utiloe administered. The divided muscle will reunit itself to the sclerotica within three or four day, and whiie this process is bein, aecomltished it is well to batndagwe t]he sound eye/, so as to comptl a central position for tle otther, and inlure the att ent of th interinu Ilhiild its lfo-rmer i f nsertion. T.he dtail or ocaionat exercise of the squintilng eye, by baidaging the ise o tif; SqX {: t.... sounld one, for some weeks before the opeiratioIi for the piiurpostO of restorinr aenCte(ness of vision, wen.' tl t eve 1s amly lopiec, is e on n e tlda'l 1 e. te sqin considerable extent its of o eetter to ofp)iate O'n both1 eves. Fo-)r instalnce, i the sterabisnf is tlhr!e line..s iln extent., by one operation on the al'leeited eve we may redutce it to one line1 then a sligter operation on the sound eve witll bring' the visual a-xes of both piarallel. It is best to wait soome weeks before openating on the secondl evre ill order that. t11141 full etlect on the fi rst may be determiniied. ne operat 4)n will not usualiy reio'Wve( iorIe tlitant fr'l.om two to two ald al half lines of deviattioin. The elltect 1is inerease by a fre e sepa rat lioln f sni1.eonjune'tival t issue from the mnusce! when 0peratin. The effect is decreased by avoidinlg this.'1The. effect mayV be lessened when, after an operati -In, o testintg the resuil t we find that. we have don1e to1 much. bly in isert in ig a deep e4)njiiuictival suture, bringing the edlge of the wound, antd with it the muscle, farther towards the cornea. A suture, carefully incluting the conjunetiva onIlv, may be illnserted diagonalIly, to hlasten healing and })revenit granu lati s from spring ng np in the wound, without lessening the effect. SUi:1-RG}ICA L TI REATMINTET OF ST: A B1ISMUS,. Usuall tlie s6inkling in of the caruncle and the acomnpanving' undue proninlllee in titt globe, fortIerl notict fm W.versios on thle iyelihls, mary he caused bv the various opht-halmdiae, and by cicat rices. flron1t injlries. A.rlt, of "Vienna, used to advise u in- these cases to bandage the e y, the indication being} to shorten the lids and to protect the exp osed mucous surfac8111 from the air'hile piressure is to be made by) means of eharpie and tlhe bandag'e, not nl)on the eveba ll but t the angles of the lid, chiefly at the inner angle, so as to increase the tension of the orbicularis, After three or four days the improvement will be decided, provided the bandage has been readjusted whenever dis)placed. MALJA()tOSIiOX OF THtIlE LID S. 88 itn''Opiam:.t, in iver'io8 of th lAt, is (1tu generally to old purulent or gt'raulatltr op)hthtalmtia, in whichl h:t oth o frthe disease, and tihe prolmonged Use of cttlst1ic(, strulctitural ha liaes of thle conijuncltiva. htave\ rtesultedtt. 1t is somelittines tdue, il tihe lower t lid, t::sp sodic a ftcect ionI.'l'i:hiriart -w C r>#_.>C - c:.?7>C to- -- Ar a -r -3 33 ~ ~ ~ ~ ~ ~ ~ ~ - -~~* CI - ~* i )4;i *rr _ lFf~l_,, ~ ~...~,,,.., t t e % _. ^. X,_* - r -- - ^ Cr -~~~~~~~~~~~~~~~~~~~~~~~~~~~C~ - -W -- ~ ~t~ ~ "' D ~ 4~'LC* ~P: ~ C~ rr? i i, r,?'..._% ~r. ". _;t: _ _ -i a _- _ _*- -_ C.'-.C, r o, w S W -,,'W - - C W - W -('8 v<. S -.'s_ w rCw t>, L: a. ~.,r -i 33,_ r< a sw' +~~~~~~~~~~~. I r *t L J'?*.* f+; Hw >* C - 3~. - i 33 2 ~ C 42 A" _3 t >* Irr? It AC 3 -l a - _J *L.,. v i. i i-. -, *, v,.... 3,-Ct C _,,_ a~ C. - - C I ~~~ 3 Q ~IE,-,~,'~ br CT -. - ~ -.Z~*I i i **.p-r - -= M -— ~ 0 c~~~~ ~J ~w~,u r-c 0rr,,'C-C C - - ~ _ _ _ __=,_ _ tr I —~"~,..., i r; l ACUTtE INFILA. MMA.TION OF THfE LACIIRYMAL SAC. Q91. tand the abrupttt chanlge of lthe probe from t ite l horizontal to the ver.ti cal )position, tnecessary whent passiig it fromt the lo)wer canaliculu, is avoided. Thle upperlt canal is readiy- slit with a delicate probe-pointed knife like Wbers. S. In nraIr instances the cat naiicaulus lma be obtstru'eted b'y at foreig'n body, sueh as an eyelash or a Inlllte chalky eon. tnertiontt the relnoval of whcilc etffets a cture of tIhe case. ACUTE INFL AMMAT.ION OI' TIlE L.ACIHRlltIYAL SAC cot.es on rapidly, antd is often listakel for erysipelas of tile fe,.The region. aboutt the inner angle of the eye is exquisitely sensitive to totou.c, the lids are red and demnatous, anu d the in fiannation and pain over the sac are intense until it burst's, w'hent tomplettte r elief ensues tl'11. cause of inlhtinmatii.on and suppuraft iont of tifs kitl is very likely( to be a ptre.vious obstructtiont to the flow of tetars due to a eattarrh or blentorrelta. HRetentiotn of lthe secret ionk in the sae gives r ise: to dilatation and thylpertrop:hy, and: f s favors th l format:io olf a:bscess. Jepetated suppuration leads to complete) ob)sttruetion:s of -the passage, to lachrymal l fisstula,tand to dist ase of ithe laehlnrymal or superior maxillary bone. N'asal ptoly i sometimes obstruc.t t:he lachrym-al passtage. }te ttre atmlent of these diseases of the lachrtinal dutet and sac will necsstnarily be meealnical. as well as medical and topical.!r!eatment qf tAcute I./lanmmatio't qf the Sew. Aconitef and belladonna, in this affection, will be requi red intertnatlly, with cold, or perhaps icc-wiater cot - 292 ~THE LXACIit{YMAL APPARATI'tS tiresses externally. By these iears tIlie formation of abscess and btur sti g of the sac, or the necessity of lancilng the sac, arlc frequcetly avertedt. Another means o1 taverting pe)rforation is to slit the upp)ercanalicultel s, and tpassingl down at narrow lkniife, incise tlhe neck of the sac, which tmakes tt free openinlg upwa-rd fort1' the exit of pus. If the dise ase plas roglressed so far that suppllrattion is inevit'able, it is better to lchange from cold to wat- applicatitons. If the sac' is ver y mlucht swollen, and tl(he skin over it thas beco)me thin, so th at; burstil ng i ii uininclnt, it is advisable to t)o lay it open in a downward and sliglhtly outward direction. If left: to ind its owln tway out, tte matter may escape at soe ulcerat ated porttion of the: sac, which }perfits it to flow bCene.atht the adj0oining cellular tissue, and tulls create aidditional swellings ttand finally filnd its way throug'h the skin at considelrable distanlce from its original seat. Our object 8sould:be to )prevecnt comlpl:ications of this kind, and to give the freest tand spc(diest t exit- t the pus, After open)infg, tle Iilps of the w(tound should be kept lapatrt b)y a t- it, of lint to pertmit of free disctarglc, and the swelling poultiede if ttccessa ry. After a few days, when the itllaminat ion hlas subsided(, the canali1'ultus should.be op(ened, and a probe pIass ed into the sac to a. fford a free ent11trance and exit fo:r the tears. 1The external opening of the sac may then be allowed to close. If a considerable discharge of muco-purlulent matter continuets, tthe sac andI duct may be s.8ringed out; with cold watecr daily, or with som'e antoi-septic solution,.. ten grainls of b}ortacic acid, or five grains of argent(ltum nitricumn, each to an ounce o f water, I often use. The solut ACUTE IN XFA MMNAION OF THiE AC I YI AI, AC. 29 titlns are tlo he. employed daily, or every other day.'lo syringe the sac tthotroughly, it is so0mietiit cs req:uisite to patss a can tnulal (tqite into it, arttac:iltng the syritnge, like tlhatl otf fi, i, tio e mlolth of the canntula afterwardts if neewessatry to thlie inlt rotduet ionl of tlhe {C'.annulla, whicht is I'erlthaps as lar'e as a number four to six of the B:8o'w-o man pltroheJ, the neckt of t sac t a and tle intetrnall ) It'ebrudai fl ga:ncelt may be incised wi-th a probe-pointed k nife,.'1h0 select'tion of ilnternal remedl ie s a\ lry much cntrolled by the general co:ndition of the patient and by C TtEMAUUtt & CO,. Fie. 70. the d.iathesis. in serofuilos suILjects for instance, met rcur,, sulphide of ctalium, or iodide of potash s.emn to be especially suitabte, and will be indicated stonetimes by withi the disease in question have been sertvicr teal. lI chtromnie eases, unless very mild, and of periodic.al. re — currenee, when internal remed ie(s ar e urative througph the restoration of the general health, mechtanical tmeans will be necessary as auxiliaries. 294 tHEt; A YX''l,''II't tiMAL A PPAI.t IAT U'8. D)Il.,ATA1TION OF TUillB AC FR1O1()15 FISXA,' F.ilinnt pressure upIon the sac will hlasten its reduction to the nolt:rmal size and conditiot.'Tlhis clan be made )y a thlick..contlmpress held in its p1lace hby a bandage. In clhronmic dilatation of the sac,, where it is desired to a pply the, pressure for a conlsidcrale period, it lits Ibeen found convcni t nt to tue a slimaill spring truss, at taictettd t() a tnarr1(w blland passing atround t1( head horizontallty just tove the ev'es, and kl)t iAn jld)ace by another hand rutnintg over the lheadi a at righ:t angles to it: FISTULA OP fTHE SA( A, Int old cases where the bursting of the sac has occutrrCed, tt re1peatedly occurred, a fist:ul'oul olpe.nitng throttsgh the skiln re is; and th this chan neltt the tears flow over tt ctlhek. It theste:.scases an. exit ft(ort the tears should hetl mInade lbv dilat:iding tihe passage from albove.'he fistuht will thten heal of itself o(r healingil ma v')e 0t astene:.1td b}) toutt]ing' t}e edges otf (the ope)tnin(' with. a crav(on of mild nitrate of silver, or s.ulphate of ettopper. In c'asets of ti ikind, d'isase of the bone is stomtCim 1es present, and trlealtmentl, if undertaken at al, is often uinsatisfaetory. CH(t110(NIO CATAIitR Ott BILENNOltRt[(!A OF T'! l! tACtlIYYM AL j PASSAGE1T8, l.maty result from an acute ilftlama.lln:ltion of the sac; more freque ntItt it is an extension of oa nasal catarrh, and in DmV expst:>iene, it tappea rs some1timtes to be an idiopathic disteae which comes on slowly and insidiouslv. CI t lON IC C ATAIIIIH 29 I 5 A patient presents hlimself to be cluretd of "' waterintg of an teve He w:ill hardiv bc able to inform u.s accunately tof t:he tate of the commenceic nt f }lis trouble. It waIs first noticed inl cold weathert and (especially whent out in l cold wintdts. A fterwardts, it was tllnovi iln-doors, ocCasiSttonal anld now the " watering " of the eve is co(nti nlill(s. We diagnose tle case at'once by.'puttimg fi.inger over the laefhrvylmal sac andl pressing' gentilv upward, whelln a mco-scrous discharge wells out throughi thile puntctum. It.t naIy be possibl.e at tris stilag ofI the tafi'ectiont to press t1le contents downwardt:1 t h rolugh the tnse. ltowever tins may be, if the patien::lt is willinL to give himself tlhe trouble to'press outt the contentls:of the sac sCeeral tif es a day, atvoid cold winds over<-exertion of the eves,, and pay prop'(er attention to the counition of Iis general h ealthI, t:he clhan.ces are that lhe may go on for years, and lperhaps for a lifetime, withoutl any increaset of tthec disordter, In, addition to these hy gie ni c re la tions, mild c il l vri of zi nc or al t ttum dropp'ed itt e ti it t inlr corner of the eve will oft en prove g,..reatv belefi cial 1. I have occasi(oalkly eIfected a cure h sy rin(ygint the passage with inwild astringents withoutt rcsortt t'o tlahe robe. F'urtxhemor, nwhent the gcineralt healtth is at faulty one may sometilmes remove the lachryltmal dis order by restoringl, the systenm to a healthy state, Tr'eatment by Pirobint, Patients are frequt ntly imin patient luder tlth above treatmi ent, anid uItnwillil.rng generaltl to follow suchl strict hygienic rules; they desir e a treatme.nt of somle deinite t^ ^-_ X^ _ ^ o^,5^ r~ " ~' C ^ -S -t G3 _ C - _O C o *- rC - >t,e OC,. i _ cY 0 0O -~ C O' X > n. ^; ~:? X z ^ o *, ^ ^\~~ * ^ ~' ~- ~. j. 11 ^ ^^ _~~~~~~~~~~~~~~~~~~~ A C i~ ~C ~ne,,, ~-S a ct P_ O.*'Cx U rSr r r~U ~( l,, r. ": C;S r MK ~ -C W 1 63 I ii C:~ ~~ zc 0- e V';3 ~ ~ ~ ~ C -z~~~ ~~~~ 0c - r-" ~"~ ~ 3*~ - s.XtNCNc: ~ O-, ct," - -0^^ ^__~_______*0 ________________________ ______^^ ^ 000 -4- -p ~c4- 3i 1 ~ ^^1.... C O ~ c I I - - a - ~^ ^ __________________________________^^^~.^^ 0 ^ -..............'^'~ P* rZ r^ T ^ ~sr ^ ^ _................. _... _ ~...^ _...........~....... _. ^...................~........ ^ ~ 7? a~ I- 3 C11X:ONIC CA'TATRtHI., 297 ingt the probe in a hoiontal direction, inclined slightly upw\ard, at the sam tlie i stretching the ittcgtueint s of the lower lid outttward. 1-tavin lt reachedt the sac, as determined. by the firm resistance of its inner wall to the end of the lr, ad heob, ad the observation that the. inteCgrumtl nts a t the inner angle of the eve do not aplpear to resist the probe otr move forward with it, we turn the inst-rumentl in a vertical direction, and pass it do\wn into the sac. To tilll( and ietert the lnasal duct, readil, thle direction of the probe wvill 1now re1quirle to be sligrhtly changed, so that its extrcnintv shall point a little outwardt alnd: forwardt atl, having entered the duct, i is to be pressed gently downward to the floor of the nose. If operCatinllg on the right lachryal passage, we may hold the prtobe in the left hand, or stand behind the patient:anId use the right lhand l}te probe maty remain from t t te tw\\enty minuttes nlesst irritation or pai is8 felt, in which case it may be better to leavxe it only fr-oml olne to five minutes. 24 stricture may lbe s ituated at any point of the pass:age, Its I most frequent seat is where the canalliculi join thle sac, or below, where the latter is narrowedt into the nasal duct. It is to be overcome by firm, but gradual and gentle pressure downward. Frequently a change from a larger to a smaller probe will be snecessful, G1.enerally, howmever, -the larger one is to be preferred if much. pressure is ltecessary, as less likely to lacerate the liining membrane. Tact,t gentleness, and sometimes a good deal of perseveraIce are requisite. One may sometimLes try for two or thre ee weks, at intervals of two or three days, before overcoming a 29f8 T'I i E T.AC1i I Y MAL, A)il:'lA AT AIUS,. st:rict:re. Whe.n w I e find it impossitble to enter the s.ac from the low1er canallticulr1 we mua succedt, perllaps, from thle upper, or it imav b.e n(cessa8ry to divide the str'icturl,'beforet tlhe probet can be.troduttced,iT with a intrtrow: histounr. W\eberi' delicat )o e-ointe kt nife, or the.' narrow knife, of Stilling are sait' abl le'b. l'he cotit (al probet of Weber (Flig. T8), wlhich increases rapidlyl ~? ~::,:GX?............... in size f'rom th: point, mXnay sometli'nes be 11'ie d as ay d.ilator to advant:agee, and the use of the knife tbs dispentse. d ith', Occasio.:nall', the lini ng ofit t:he sac is so muchi thickened frotm inftilammatiion atdt swelling, that it st(eems imnipossi{ble to find tlhe entrance of the nasal du(ctet frlom thlie sac. ti such instances, we may do bett'etc to r.'elinqlish all attempt.ts at probilng until t:iite and the emt )loyment; of loc(al and Eonst it ltional remedies have i'edt.uct..ed t:l.e inflamlmlationt so'ielwhati\ w\then tlhe lrobin'li.mav h again attempted withl beiter chances of snccess. i tnaving once succeed.ed, the operat ion sh}ould "be repeated on every second or thiird day, syr'inging' also with mild anti-septic solntions, until thte flow of tears thl rough the passage is mlunimpeded,'and the secretion becomes normal in quanttity and appearante TX't[ USE 0s O TUE STYl.Ti., Attemp)ts havee ten made to.obviate the necessity for repeated proabilag, by the use of styles. Unlike tthe old-fasniotned oncs, these stSyles are intr odtuced like the GENERAL I 1 EMAh RKS. 2993 pt)obes, f1ro0 above, atl.d are to bo usedl for some lmoltlh)s \\t When the dischat e is nt g'reat thel y may )e wo\ lt dtay or weeks without chIang:ingl, andt it is clai tlmed t-hat the rritaititon set 1up) wvlen the st lte is firlst attemnptedtr to be tworn', Soon1: passes off, ali thle tptient filds it con fortable. lThey are matde of silvet r or leadf of diffieren.lt sizes, afd tl:may be fa ttenr.ed at tht e upper end so as t:o:be. bent; over the lower lid like a hook. The st yles atre of wire ftroi one twenty-fourth to one twelfth of an inch )'or t'more in diametert and tt, one and thlIree-farters if for the lower, or two inchies in length if intended for the ut ppe9r c anal ict lu ts, MI x'ETiOD) 01F STIitXl:mNi, Tihe( method: of Stilling plroposes to ttcure the disease Ir.adically 1 by a single operat otiont. l iest fit linds the seat; of th.e stri.ctut.ret b- probintl andt then withdrawingtll the probe, intt'rodbucls a smi 1 in. ar'row knttife in its place, and irnc.ises the stricture in three or four different; direc(tiot.. Tlhis methodt wit} probing ort x th:)e w'tearintg of a style afte:rwards is ia usual one at tIhe Moo:'l ields I tspital, London. IT t may be a der dier retssort in obsti nate cases, even if too'severe a procedure for ordilnary practice. O N ERAL.tEMAIIKS. The m-ost frequent obsftacle to the permanent; cure of catarrh or:blennorrhllealit is the thendency of the laclhr ymal passage to close again after it hiras been successftully dilated. 1: believe tlhis tendency may be bes t overcome by a modlerate and gentle dilation of the passages, and, when possible, avoiding all bruitsiing, lacerating, and 8o00 TE LACHlI YMAI' l APPARATUS' even ctutting of.l the lining tmelmbal)u'tn, alnd tl-llhen by constituti:Moal and local remedies endeavoringt to resto( rvt the diseased Inmucots surfacet to as lhealtlt a condition as possible. Professor 2Arlt, of Vietnna, rarely wvent beyond the No. 41 Bowian tprobe, in size. lie preferred not to risk a ru)ptirt of the epithelial lining of the passage, and relmarks that at its nasal portion its normal eapacit:y is not mluch greater thanl a No. 4 prot)be, and tlat w where the caalnateuli join the sac the diameter is less than that of No. 5,' The following is his meafsurement on t.he cadavre of the sac and diuct,. AmilliXmetre is equal to about one half of a line..... TFtiL SCAC. THE- NASA., )UCT, Lengtlh, teln. W idth, four. An- Length, about ten. Width and teroposterior diameter, two antero-posterliot r diameter, each iXlllimetres. one and one-half to two andl one-half millimetres. in the zeal for dila-ting the duet as \widely as possible, so as to prexvent its reelosure, the eatarrhal inflammation of the lining membrane and the diltattion of the tsac tare over(looked. I often succeed by using a. No. 2 probe alone. Here is a- case in point. Mrs. 1, Wetmouth, had suffered from blennorrhOcea of the righlt lathrytmal:passage for thre(e years. Matv 22. I slit the lower canaliecuus, under cocaine, with scissors, but did not succeed in passing probe No, 2. M:ay 24. Passed probe No. 2 after injecting cocaine into the pnssageM. Mtay 28, 30. Passed probe No. 2 in th e samc wayI. June 2, 4, 8. Syringed with two per cent boraci cicad. June 10. Passed probe No. 2 aain. June 14, 18. Syrillged with bi-chloride of mercury 1: 20000. June 27, July 8, The eye is perfectly well, TIlE LACHItiYMAL GIANI). 801 Th'le permelability of th1e tear passage, altholugh a necessary stage in the progress of cure, does not always.com)plete it.' he abnormally dilated sact is to be rleduced Iby Iprssure, and the catarrh treated by lo cal and constitutionotal relmeldies, otherwise the germs of flesll itfltuamnationa s are left behind, and the old obstructioll reapl)pears. OTH I'R OPERATIVTE M EASUEJS, "lThe operattion for obliteration (so called) of the laclhryvmal- sac by incision, and the applticat ion of caustics, or the actual cautery, lhas fallen tnearly ilto disuse. Thei sac is rarely obliterated by thle operatilon, and the result: is generally nusatisfactory. It mttay be dissected out with the knife with better result it is said. THE L.ACHRYMAT., GLAND,. The lachrymal gland is subject, in rare instances, to acute and chrolnic 1inttlllmatitons, hypert ropt)h, fistula, and to cystic formiati ons.'Itle acute atd clhronic initlallnmatory affiections of this gland are atllnabtle to such treatment as would be suitab le for similar affections il other partis of the body. The disease of the gland is so rare t'that dettails of symll.ptoms and treatme.nt may be left for largerr treat ises. In mitore tlhan one hundred thousand t casest of disease of the eye observed at the (Ohithaltnic Hospital in Lolnldon, less thant twenty cases of affecti8ons of this glatnd tare recorded. It li-as been observed recently dturing an epidemic of nmumrps in three or four cases. CII APT ER X\ Il. AF-ECTIO NS OF T IE WHOLE EYE AND O] TUI E O(IBIT. Ii Y l:)i() PJ { Tt i A i,5 I, T A.: A Kl A TO-()I;,O 1.1 US, )Ut0'P1SXY of the cve (so called), a ffcets principally tlhe antlcrior half of thle eye:ball. Th pelculitar stare w'hich the p)rominllelnc of the e'yes give:s tie )pastient is very.striig. The cornea) are increased in sti(e the anteior chelatlt)e rs i ept ad i rie)t, aarc t re t mlonu us for lack of sutpprt. The pupi: )tils are dihltted, tand so)mnw times pear-shaped, and tltilmat ely vision is im)'ore or 1less imp air tedt, iThe selerottica grtows thin altnd bluisht a.s the. disease'prog.'resses, 1and all parts of the eve are finally in. 1vollved. The'lc prnogress of the affect ion is nsnall tv slow. It: is prRohably incurable. Reined ies like arsenic, mnerury,l aind t]hose suitiable f::r a-ffectioni)s of the corneait g enera lly mavy be presriibed, in the hope, at leatst, of retardill n the progress8 of the ntfaladv. t urgi ally repeated parace(ntesis 0corneat and i ridecttomt y have been productive of benefit, EX`OPIHTXIf AI AMi C (OIThtE (RA V ESA DISEASEX, as far as tprogressive bulging of the globe is concerned, re:selmbles dropsy. of the eye. It is associated .)tlSE'ASIES 0.F''TIT OFB T l10IT. 803 with ihylpert:rophy of the thyroid gland, palpitation of tle heart., allnd subseq{unt dilata tion of its cavitices, antrinia, viscerl al dtcl raitglttccXints, andlt, il femalt(s, wittl antil. (trtrhot a. I'. h diisease iS talso accotmpan tied by great tnervoIus excitemen t ttand somettiune a caj(tl)rlicioull temperl. ts pro'ress is slow, and the prognot.sis is n.t as unf lrmly un fa.vt;ralbl as ill drol sy of tle eye. The treattment cann.ot be laid dtown, on accottunt of the a(lost tnumbl)erless coim plicat tiolls whic(h the dise:ase may p-t'sent. I y ropathic trecat ment is to be favorably mentioned as Ihaving 1be en serviceable in t:is affection and receCtly strophanlthus is reported as useful. MI)ULLARIY.ANCER O0' TIE EYE EDl)tJ Cl NN(1,t 1 (. 111 ( fttfE lk G.fXj lhas 1)1bee spoken of unt1der teh nane na of glioma retintw. httlamfotie eaneer i is probal) tc santlcE (tist:tse, witht the add t iti> n oi more or lesos black pigmien:llt in its sstruc tireC,.areoma is a recurr'elnt growth, req(uiring~ similar treCatment to cancer, ttt exhibits less tendelanc to s.condary tdeposits. Before brIeak-ing tllroutgh the anlterior tunllics of the eye, it has been mistaken for gtlaucmna. ] it can otl tI litt listlb i / tt ) o ~xllicte:: osco ics:xonly be disstinguishcd fron cancer hby m icrscopic exatmiila'ttion,. Oph/tlanllitis, or sulppn.ration of the whole eye, is noticed iln the chapter on0 the Choroid. DISE:ASES OF' Tl:HE ORBIT. I have not the space tot speak in detail of diseases of the orbi:,:and mulstl refer the reader to works on general sltrgery. As regarrds diagnosis, tumors of t-le orbit are accompanlied by more or less prot xrlsion (:of the eye), and rb dimninished Imobiltity of the gloile, and soonel r or later there is impaired vision. In inflammation and .804 A\FFlUCTIONS OF WHOLE EYEY 1 AND (Oi)rBIT, atbseess of the cellular tissue, there will be added to these symlptotlms pain in and aroundt the ball, and tenderness xon presslure of the globe backwaXrd. l'umlorl will generally rjeuire to be removed together withl the eyeball antd inllamlmaltion and atbscess will delmand the same gne.neracl t treatmlent as if loca:ted elsewhere. CIFAPT'ItE:' XIX, INJ[OmRIES (OF TUiB: ESYE. TIt I1EN:XY: EYtI)S. FI.B contlusions ani I.1d eclchv l oses of tih ey elids we lhave exccll.nt relmedics in arnicaa, latlnal-elis, and calenIdula. I lacerallted or incised wounds atre to be trcated as tusual in othet parts of the bodyv, except that esipecial (car' should be takien in accuratClt'(t ai)lox itilalt the edges of suchl wounds in the lids, so (s to guar d against deformlity. In bt}urns and scalds' gre'at care will be nlecesskary iduring the cic.atricial period to preventt plastic itunion of thet twXo lids it; the angles.'Thiis is to be prevtited bty ilnunctioon with simnple cerate, and tlb directing thfat tl e lids be freqtuently opened. To prevent cctropinlll aid ait contractiont l wh\lich migh', llt prevent the eye from closing (Iagollthallmos), the. lids should lbe kept its much as possible on the stretchl, and be bandtaged w-ith extreme eare. For the same reasions it is always advisable, when possible, to bhring the edges of wounds of thel lids together byv fine ilnterrupted turee, ratlher thtan lea ve t:hem to unite by granulation, and risk. loss of substancee and contractionl. IN JURIES tO TiHE CONJUNCTIVA, of ta clhemical nature, art (lquite colmmoni.'Those from quicklim.e arle of the mo0st serious to which the eve is 20 3806 iN JURIES OF TiE? EYE. sutbje.et. Complete dtstlructtito of the tissues of t(he lparts tvith whicth the limle comes inll c(fontat lmal resullt. Stlahked lime, mortar, and plaster are n0ot so'rapidly de struc:tive in their effect, but may in the eanld prove inearly\ as fatal.'lt i (b elief danger, event iil c tes twere the bih i t is. nt ver y extensi ve o rvy deep, is il loss of sight fro.n opacity of thte corlnea. Th e wtititeness of the corntcal oplacities in these casets is very mat- rked, and it has bIeen shown that the ciceatricial tissue reproduced after tltese injurties contais 1iins lme. ihe, Treatmtent. It is wiser inot to attempt to to (lntr(aliz the alkali lib the tse ot wefak actid. 1Tht eye is ittolterant of4 acids i.n these cases, and they can hardly 1)e of stervice iiniless applied immediately after the accident. It is bettler therefore to resort to o(lie oil or liqltuid vaseline at once, a smaltl lquantity of whichl is to be droptpe''d into th:e oye.'Ithe lids are t-lhen t: o he e'verI:-ted a tthe loose particles oIf limet remove(d with a d. elicate spatiula. t!I Ift the epit.helia:l ltayer of the cornea. is dlest:roy)Nedt i't shltotlt be removed, and, i:f possible, the cauteriszed port:ions of the corneal sublstantce should also be take1t off, so that: the treiproduction of tissue may nott ot nly be spyeedy, but thalt tlhe nlew tissue may beN free f trom dep(lositions:of lite, and trani sparent. After thle Iappl:iciation of at few drops more of sweet oil or vaseline, t-he lids sb|houl. I be closed, cold-water dressings used for the first few (days, and aconite administe'red. In injuries from l strongl acids a solution of.catrbonate of pottsht, or soda, five graitls to ta ounce of'water, 1may INJUtRIES OF) TIIlE CONJUNXCTIVA,. 3"80" be used at tfirstt if the eve is seen sotl after tth inljryt whienth this is not convenient. warm water Xmax be su.)bstitutetd. ()live oil should then be used. In b1urns atId stalds of lthe conjtunti va. frolm ht fluids, olive oil sholl:uld also e apd: {prlie d, the lids closed, 1and the eve'. itlitt t batllagl'ed. ()il should b)e idrol)tppe into te(- eve two ort (three' times a tday, the lids cletansed from all disctharlttl'e, tand the lbanldag(0,e re(adljustted. lftituies tfrom. t tutpowt der attre somoet ines seriolus, not only fro the seorching and burn ing of the contjun(ti. va.. fromt the e-xp<:losion, but from the circumstanlee, also, tat:: xtll:x.)lodled g.rai:ints of the powder are depi ),sit'ed in aitd u:)pon the collnjt'.ti va, and are r sometti res for:ed'(' tlhr(ouTg h it; int'o the tissue of t h:le scler'ot:ic, aInid often imbe(ddcdt in tIthe substtiance of the (lcoea. The lids tare to -e e:veed a\nd syrillteld syto as to tremove all loose p(.)owde.'r, 1thenl aill stuperfllit iallyv lt t ibt'dded g'ais i (he cljctiiva iland (.o.:rnlea are to b.e lremoveld witl the spatulal, brtoad needle, or )tcrved scissors,' anlld o liv(- ot.' C:ast::or oil droltpped into the1 evye or thr tw ies a (lay, t and stuch:l e.(:..l al' treatl' ent resorted to as seens:. essa ry. i:ii.ic.t!l i.nirwstri: of' t/e coin tva, from.fo reign htodies sllc as cinders dust, particlles of i ron, steel, gltass, tand tlhe like, t neral ly oc.tcasi(o a gtt'0oo d(eal tof in jecti on, tand )ot tlt unt'frequently severe. cili ary Inteura lgia, plhtotopdh(l!obia, and i aeb(h rymat ion,. In the case of a Silngle. fotreigu t hod^ l'ike a rcintder,' iit will gr'erltr'1 tlt be foui)tlt Ineath tt the uplper lid neItar thet edge, an1d tra re ly fatr lba(.k in the retrota sl trsl egrion. A. smldl sl spa: tulah may be used to remove it. It:: is not worth while lhowever f or a stur-,geonr to adttemt to t o this xwithout everting- the u.pper 808 INJUJIESS ()O TImE'EYE. lid, nor \b the inttroduction o: other foreignt bodies, like sio:l.oth pebl.)les called eye-stones, or slloot11h rloundtl seeds. tLeave( stuchl proceedings as tlhese to the foretmen of establishlellnts, attnd to domestic pral'.ctitionters,'the mlet.hod of ('everting the 11tiper lid is described elsewhlere. A. yetar or more a0go a lady catt me to me for a eontju l tivitt:is of oe eve', accompll)anlied by severe ciliary irritattion tpainl and 11ph.oto:ti )lobia(;. Sloe ad been fotr lthree (.lweeks'ultder tlhe treatmelnt of a. colleague, alntd during all this t:ilne she tholught that she had(l not1 had 1one comfortable nightt's'-rest,. l1ert symptomnl:l Is all ptointt(ed to a foreign bodvy, and on ever.t ing't tthe uppter lid t1here lay, p:a 1titall imbeldd(ted ill th te ustae of the onunctival, a minultte h1it of tuartz with its shlarp ( tedges and angles. She h.ad sulffered for three weeks, when the exercise of a little citrumsptcct'ion) would t have relieved her att aty timhle in thllree 1inuttes, Slplilnt ers or ot(her substantces betneathl tl. conlutncttiva, if found iimpracti:cable to t'remo:)ve wvith delicrate fortceps, Imay be cut out t wt ith curved scissors. Imiplpltat le par::ticles of d(ust or sand:lmay be washed out withl tlthe syringe and warttlm watert. T't use otf cocaine will render these 1tman ipullations com)paratively p ain less. Ill the "A. ttrican Joultrnal tof the f1ed ical Scientrces, \Vol. L. ip, 51, among other cases of neglhected foreign btodies in thet eye, is thatt tf a (l eran whto was treated somet time for granulated lids, until fithially the cautse of the affectilon was discoveredt in at negleted " eye-st)oe which he had lput into i's eye six mio(nth1s previously, and \whrich lie thought (:had dropped tout wVit 1 1e he ws asleep, as his wAife said lshe ha sseen it in tiie bid. T1t'h tremoval of thle " ete-stoine " cured tthe eye. 11 the SN MBLEPIIARO.N 309 "O(h)l Ithalm.ic n view, Vol. 1p.. 3, is rela ted i full t t:h ca se o lf an 1 l man wlho fell to the bottom: of tlhe stairs, anlt( applied to a surgeon fo r a' wtt. inl the con.jlnehtiva. at the inne.r angle of the right eve. A. ftcr a: week's trecatmtent the tresc'nctte )of a ftoreign'(body was suspected, and the:next day at clast-itfron hat-peg three andtt tlhree-t(:etlht i inches in length wats d.rawn frotl tlhe toundttt. lThe plat icnt irecovcred without tunflavorable symptoi'ms. Stall p:article:s, like gravt l or dust, are to he relmoved b)y e veurtilng t]he lids anti. syringing them and also by th t:c use< of the spatula. or blunt pro)be, when nccessary. See Fi'i 8,t. 85. A N(Ht{ Y I OIILEPt ARON is the un1ion of the mlargin of tlhe lids with each oither, either directly or by n ltembrtanous bnlds. fit is a result of iinjry, or nllceratt ion f.rom dis(ease. The Tuion is to })C sevefr'ed withf the scissors or tlhe scalpel), and rettion prev ented bty frequ ntt seltparation, and by anointing the cut surfaces with olive oil. SYMt BLEPl l A RO)N is thelc unimon of the inner surface of the lids witlh the. e eball, and n tay a lso b e tdi re(t al nd cl.os, or hy n metbranous hands. In thle latter ease., the blands of union. may be divid(ed., (and daily dressing' withl olive oil lmayt possibl l prevent a reunion. ( ctnrally, however, ald esptecia-lly when the ladhesions are at all extensive, it will hle necessary to resort; to an operation,.namely, the sepa.ration of the< lid from the )baXll, and t I he tran splantingt of conjunctiva flrom beneath thell upper lid to 310 INJUI: S TO i EYEI. tlhe lnew surftace.'T1he caluse of the affcct ion is an injuit', usllually a b})lur ftrom hoft tl1uid, It tal, tliie, orl mortar, D)IA(.NOSIWS ANDI TREAT:^'tMENT OF FOREmIGN -BODl)IES WITHIIIN TI E (G LOBE. Tlie diagntosis is s )(omettilmes( quitet difTicult. Wtheni tte f(oreignt body cbati(ot bte sc..,en witl o(r without; th. taid of ateral illumiatiom and the op)htlmolno pe:o, we tmy 1uect itsay it C presence: -- If the p)aint does lnot yield to the ustual ptalliat:i ve treatIntfcit, and is aipparently dislproportionalte t to ti \visible i It tt fill mat ion. If thel infltammationl does not appetar to be cont rolled lby tlte trea.tientll: t, to thtte tustuatl extent, If symttNtIloms of inflamtnmation of the deeper strut'c'res of thle eve, are l'present. If tthre. is ta c irtcumscribed iritis with ext dation, limited to( a given point, no foreign body b:leinglt \visible, the eve tha vinl been.y a st ttrk l a splinter of tme}t:al, I recall at eas t like tis i te inic: of Vo::nt (ra-fe't,) a famous etase where I happened to b. e present., arnd in whicht he( maltte aln iridectott0y, and( tthetn removed the invisible b it o(f metal ftroln bltehi:nd the iris. If there. is no)n-union, or only partial union, of a. wound throtugh wict a fotreign bodty nttay have centelred the eye. In cases liIke thl e above, where tihe irritatiton: or inflainmatttion is contintuous, an attempt should lte madle to find antd re)(move the foreign body, a)nd:failing in this, the eve shlould be removed. Whlere the foreign body TII - U8iE OF T)tE MAJ GNE t'. L31:t. can. )b s'ten1 it shltould b!e remtovedl in all ctases -when it cant )0 donle e wtitltout tselriout s risk of loss of t:le eve. It must bo ext rlact 1ed t ant hazard t t::o te e v if irritation l, l)atifn ad intfltanunationl are engendlt ed by its presen(,. lest Svm:)athett:ic in a1tnlat-ion dtesttroy t:he:' otlher eve. I nfianlm ttion re urri ng in an eye which has lost all visual povwer from former injury, lwhet:et the l resei ce of a f'oreign body be suslectcd ol nol tc dmaniods the remloval of the eve. When a foreign body, like a, bit of percussion catp) for insttancce remaini, i the eye, btt: callses no i rritattio, tie sight of the eye te tingtt inil ttt aii ed it i t, and its ext:raction would. be hazardot s to the eye, it may be left n it is place; b.)t the p1atientshould he cnligltlnct d as to tohe tnaturtle of the risk hle is takingt, and instruct ed to rleturnt to tl h surgTeon if sym)ptoms o)f ilrii;ation cte on i tlhe injlttfd'eye. TlHE USE OF T! I MAG(NET IN TIE, Im IANOSIS ANDI) R -FIMO VAL. OF F)OREI(:N B(OnDI I:S FRtO T'I E Y'I Tlhe em ploxyn:lt t of the lmlagnetl in ophtha:lmic practice is not of t relcentt origitn. h11e ". B ritish Medical J(our.nalt for JItNl 17 I 8, 8 ix gives the f ollowing (utatti:on bearing date A. 1). 1. 745: "''er was one in Salisburv hlho hd tau piece of iron or steel stuck. il the i ris of his 0ee. The tperson was in very go:'at painl, atlt CatlO to me. 1. ende1avored to plush the iron out: with a. small slpatuhla, but could tnot,, and then applied a loadstoe, tfo it, a'tnd immediately it: jumped out. " There is lately a lrevival (of interetst in the use of the magnet: antd a n1timber of s- 1uccessful C ases are repi)ttt ed. EHither pe)('rmlianentt. or elect.r'o-nmagnets are tsed, anld the foreign body to be 312 INJUx IEwS OF IZTE EYE, re\moved must, of course, e a fragment of either iron or steel. The prwesence of a bit of either of these metal.s hiddern withilt the eve mat sometimes be ttm e lkown b: the pain induced thouh thie influence of ta powcerful matgnet h1lcd near the affected e et. 1 f, hto'wever, an tWe iln 0wlich thert is knolwn o suspected to be a foreign body lhas become blind, there should be no hestitationl in advisin its removal. Pelrhaps an excpltioln midght hbe:.tmadef if tlhe patient is intelli-gent; and lives4 near tlhe sutrgeon, and: thl e eye is painlless, and not tenlder to the toucth in the ciliary region, THEI: I COR':NE,:A. Injluries of thei cornea lare mlore to be) feared than those of the conjunctiva, from the factt that opacitics upon t its surfac imnpair vision, Fragmenits of metals, or sp)linters, in its sublstnice occasiol gtract ci liafy i-rritati(o, itailn, injection, plhotophtobia, and ltacth''lation. If tthe foreign body, owing to its smtall size or color, is dillicult of detection, tlhe puptil m1ay be dilatked with atropiln so as to cnlargel tlhe dark bacItkground, antd the oblique illumination and a magnifyingla glass eImployid. A delicate spaiutla: or broad unet dle mary hbe used for removingt thel. forecigint substane., and in ll: cases cocaine i to be used. Ch m.ical injuries of the corneat may be treated as directed iunder Illnjuries of the Con ( junctiva. Clear cuts or punctures of the c'ornea he al readily, and generally leave no scar: behlintl. The d(ang'ler in the;s' casels lies in the possibility that: tth iris or the lens ma hlave been wotIunded, and ilritis or catiaract supecrvene.ll The treatment of wounds or injuries of thelc cornea re'(. TilE IRIS AND) LA:N'S. 813 (lircs entirte rest of the eves, if thie eltiary neuralgia. be eonsitdrablc; wan:r f>lomientati ons and the instillation of atiropine and cocailne as palliatlives are rleqtired. (live oil or ca'stor oil is ve'r gratefutl to the eve after the remnoval of a foretign bodv and in abrasions of the lepithelial surfacee of the cornea, andt ai simi.t'lie btadage should be apptliced over the closed lids. THE X iS AND LENS. If a wolnd of the iris is cleta, with no laceration, itI may lheta at; once wit ithout iritis or s uration. If a bit of iris protrudc thrtou'gh an opl:lenillg in the cornea, anld cannot be re adily re t.placed, either b)y careful 1manipldat ion, or lie en.mp.loyment of atropinc or eserinc, it. may be excised. Foreign bodies........... such as hbits of percltssitlon c{.ap, or steel -re... mai nin:E g ili the subllstaf'nce of the. iris will taldmost: ilnv;riably st up aln iititis, andt sllt)uld therefore be reloved by an i rid cet oniyv, exc.isilln t hatt port:ionl of the iris ill which the foreign body is sitlluated. Inljuries of th:l corntea and iris, like other injuries, son(metimes result; much less disastrously than we have reason to predict, I recall the. case of a child two years (ld, that lihad run the Iblade of a pair of scissors into the right eve ti:owards the itnnr angle, penCeftrating the c''ornea land iris. I exc td, oS c urse, tratumatic clat taractt; bult the direct:ion of the instrtument was sfuch t:hat the capsule of tlhe lens was left' intact. Iritis ensued; yet the eye finally recovered perfectly, leavilng' no corlneal opac.ity beilnd, and tno def)ormity, excepts. a slighlt Ldisplace-l tment of the ptupil froml a sall synechia possterior, at the point of perforationt off the iris. Now, aftfer t\wecnty tINJU.IES O(F THlE EYE. ye\ar s, thle deforilitv is lardly nofticeable. In all wouds, \when the anterior or posterior cha;tlmber.t las been entered, the elte shotld be bandaged inmmediately. it'}mwrrutfe in to thte ateritor ciambtter iay revlt front ta wolndl of thet iris, or froml a detachmentllllt of its ciliar bortdlter. It: may htt e Bso extn t sive a s to completely hide the pupil and iris froml view. I have knol wn it:to occlur to this extent: in the operation. of iridectomiy. It is tthec:least (: dangeroust form of intraoculatr hemorrlhtagec and.l:the bl:ood is t suall stoo absor bed. Wh.en a wound oft tih an terior chamber is large, and thel iris btlges, f(tormiag a slac distedeld with aquetous hunlmo', it is not safe to excise it lest a faartthr prolatpse occur. It shtould )be pricked ait interval s with a line( lneetle, so:as to cause it to dwindle, and petitrit; the edge:s of tlh wound to approx inate. Later, it can be excised, if ne'cessarv. Traumatic cataract ]has been already sp1{okfen of,.i.et.morr/itme of blood tbinto the vitfeous is not very uncommil1on, eithert ftroin dlisease of the coats of tlhes vessels, or, as a result of a t:ramlnatie injlury to the choroifd. It is sotnetltines distingttuitshable hy a red reflex, with the oplht milltosct)l; at otlherI tithes the fttunus is cot1pietely darkene{d, and cannt 1)tbe lighted u p. 1. have treceintly seen a copious bleed ing l, ilnto the vitreous of onte eye in a1 e.aIse of posterior polar cataract in atn.othe1rwise healthy iman Iwenty-seven yearsl old. It toc1curred at t once, and duritng an iInterval in his visits to n(e. A.s this fo'rm of catatract is oftten connectt.ed with: a disease dt fuisfndi, the hemoirrhltlage is ptrobably due to choroiditis; butI in sol ilsttances the cause is more oh TILE SCSLLHOTIC. 81.5 scu'.re. I remember aI lr1l of eigh'Iteen, in appar enti goojd hlealti), \wlo had reti)atedt bleeding iln bo))th eveas. lheit blood was partiatlly a!bsorlbed but the final outtcotme wa\s a- large scototlu in titUlr eve. In a strontg won.ntl of fortv-eiight, after cessation of mnast-rua:ti:n bleediing took pltace into tthe viit rcois of the rightt eye from the cilia'r.retgilt, repeatedtly dutring t:hree yea: rs at intervals of somne montt:is, and was trepeatedly albsorbed, titti It:l ly a i rge t' heitO orrha Fll oce1ring the eve beeic amet totally blindl aeen. mnuch questioln as to wltthetfhr tihe pusttules ever, f)orlm in the corneal tissue. It seems far more plroh alhle sittce the microbial oritgint of p.)us has )(een stt(died(, thIat ahl. sresses are th: reslt tt of lthe' iltr odu t ti of )ail frot n the slti'iiiratit{lg pocki into the eve. T'lle epithelo iunll tbeing denud i ed, (the cornea mtiglt be easilv invaded tl r tl)o pathogceneti. baceeria, and too geat care could not tbo t.exe.is.ed to p!re.velnt such infection, tlleeattions, p!rol}atblv front the ptoclk, occ('ur at -itimes in it he (tonljtune>ti\va, a n.d oeeasioally the eanlallictulus lhas been' oc..clutded hr tlhe rcsultingr cicatrix. W\hile' in ac, ute inflam nat.aory rheuitmatti.sml srius ophthalmnias are not coinntim, in tlhe chro~tnic formnt alnd iln ^got, bothl the extern al and ilnteral eve mn.seles ]ma\y b}e aflfected. Rt-henumatic tpa.ralvsis of (.xtrinsie musetles, antd iritis, whiclh mav take on a reilapsing for)m, tare nlot ilt'freq-nt,. Thle latter is al.ways a:ldanget)rous coimil icat:iont. s:iphil.t,i thle sour'ce of so maty lIhyxsieail ills, mary mantifest itself during its course in anytt of tI(he st': ruct tres of? the eve.'he iriis is most commonll y at ffect.ed, adt tlhe inflammation is usually of so passive a ci:a. racter that; extensive adhesve adhio:ns may already halve fastenet'd the iris to the lens before the trouble is d iscovered. ( tnmy tumoris, ehloroidal in ft lammatio ns,, a less freqtently,t retinitis, may be phases of tlis d vscrasia. IHieredittiary sypthilis may give rise to iritis with cata ract, i infants, 32i)6'T EYE IN REII.'1ATIX()N T')O THI G(lNEItRA SYSl:TEM. ani ill child'ren f t t fr t ourttetenl years of age to a p'are:tnlt vmaIt\'':lls keratditiis of a m'ost; p)er.silste':t cha:.racte:r. Scareelyc less plrofoumtlt fla sy p!)hiilis in its effectt upotnl lthe eIye is scro"fi la.'1the lids anti antferior' portion of the ball a.tre th:e plar(ts chttieft'l affeceted, andi the itflammation inay be (of any grade fromr the delicate red oin the margiin of the litds to dteep cor.neal ulcers. Pi l!ytentul:1ae:, cither of t:ie conljinctiva: r cornea, are co1lmml:ll ai tid aftel r t repeated at tttack, if the sears aret int 1the. field of'vii ion, the siHtt: is likely to oblsc. red.i tblerellsiQ, tlte eyes a.re rarely involved,,although{l deposit(s are occasitntally foundt in the clhoro(id. In rare. ittt-nstan'ces tthese deposits precedet'.( thltose in thle lttuns, andt lthe: ophthittttmoseope )may be of va.lue in dI..t.erxnlitniig at.early ditagnosis. Visi0on is not ustually inl)pairetd. At t nl t ion l as a reatltt y b>een called to t (he eves ti vatrious ftorms of.ri/lIt's disease. In the albRlnintuia of pjreg n ane, the retintitis is often rtrtpid in its de ve:lopment. Ilt st.cl at case t(he etes, al nmtost as nmu.ch as the kid{eys, nmav influene, thte )physiian in iid.tlcingt - prV(.'t4iattre d(elilveryl. f organic chanllges 1have 1noft: tfatkent ptlal in t-he retinta, I a impl)rvement 1i tl't renal c:- ondition is fo:ll t\wed by better sight,. t If eve, how ever: tntorrhag'es Ithave oecurrted and(t t:-le fit er n:'ervous strucllt:us in thet, ret imt hamve b'een, dest royed, vision mlsl:t rellmainl inmx:e rfecet unll'der t(he imost favi(rabhle ci rte mstantces. lra/ttiulr dfie(t.aes of the hea.rti and athiero. ma of the arteie.s oclasioniatlyt give rise to emtloli, wh\'l.ih ntmy l' e ca rried into thte chatnnelss of tli intra-ocutlar ctirutl ationt ausin.g bli ndnel ssl. li ao6rtic inlmstfitietinc pulsat ion of the retinal vessels TitfiE SEC(ONI) RELATIO'N, 827 can be discovered wit th e eophtBalnmoscoe. he igh arte'rial tension )predisposes to hemorrlhage -from rupture of t::lhe smaltler retimtal vessels. I)iseases f thlte ste.rual sylstem no n u frequet tly causei disturblance of sightd. trritation of th:e generative ovrgalS, depenldeni t eithter tp1)on mastturbation or oilter cause, such as a cointracted and adherent: prepluce or hlvper-sensitive and contgested ovaries ay give trise to persis:ent and obstiliate astlhnopia. Conjunctivall congestioll or( even. more profotundl itflammations may restulL'tlThe eyes are freucently influenced byr menst'ttrual re/ula:t'ities.'I havet setf.en tret: iitis as result of amenorrtl{) ca and vision was restored onl when. the menstrutal function was regularly resumnned. ()On the advent of puberty and at the li macterir the eyes are frequently'afct ted, tand slirght retf racfive errors may cau e serious dlisturbtance. In diatbetes, if the sifgllt becomes obscured, the le ns sl8tuld al ways t be examined, as catfaract occasionally occutrs. TIheo swe-1lling of the lens may give rise to an apparent myopia, and in such a case lenticular opacity mttI I al (ways e t l )ooked for. As im irlht be expected the eyes are frequently involved in diseases of the netrvous system. lt. u locomotor ata xy gray atroIphyiv of the optic nerve maray ultitmately occur; wlile in cerebral t tinors, swelling of the 1)optic nervc.... the so-calltd e d t choke disc" -'' is8 tan imlporittantt feature. Th.e va'riots cerebral nerves SUpl)1:dying the eye may lbe affected from cither cent ral or periphera tl causes, andt'(aresis of individual muscles, or of a. group htavin g tihe same nervou t' s sli suppml, is not 1ltcomtmn.1 1 I n her-5pes tLaseialis, vesicles occasionally appear upon the 328 JTin i: EYE IN tEL ATION TO TIUlBl G EN NEtAL SYSTE'M. conjunctiva or cornea. In such case the resulting ulcprs are always slow to heal. When the irruption follows the ophthalmic branch of the t rigeiminous, the ocular inflanumation is much more severe, involving as it may, the iris and deeper structures. TIIE TH)IRD 1ELA,.'rTION in which the eve munst he considered in its conmnection with the general system is that in which it mav be a cause of more or less severe nervous disturancees. For a long time headaches have been definitely ascribed to refractive errors, or to i lperfect( balance of (he ocular muscles. The paIinl is usually frontal or tetporal, often in the eves or back of them, rarei. in the vertex, with frequently a drawing' sensation extending to the back of the head. These headaches, from some tunexplained reason, are often worse tin'll the mlorning after sleeping. Sick headaches or headaches produced 1b travel or h watchingr moving o)bjects can often he traced to some form of heterophoria, and will be relieved byv its correction. Comnpar atively recent investigation has shown that more tremote nlrvous troubles imav be dependent. upon eve-sttrain. I have mvself ) the correction of astfigma tism relieved persistent~ temporal neuralgia., antd Ib tenotoml of the muscles in heterophorias overcome an insomniat of mani vears' standing, and great ne.rvous irritation. In those of neurotic tendency, the number of nervous symptoms whichl may arise as the result of eve-strain is legion. 1O'0]1 THIlE T1HIfl I) IttlATION. 829 Drowsincss is iot luncomltmlnlll, and distullbances of the apettite anlt digestion atreI freqtuent. Am:long t:he sxy toims tnracedt directly to the t, at.nd said to bc e lired b)y the (orrectiont of imuscular and refractive defects, are mental dtistturbances, al pholtia', palpitation of the teart, pain iI the ovaries, dia.rriho:ea recttal irrit:ation, etc. Reference has alretady been made to the effect obt(ained iln chorea an[d epilep'.sy, b. y re(ad}justiTng the tlmuseles in heteropltoria..Bttt in t hese protfoultder lesions the subject is still sub ju'lwice, and. it ctan }be only b1y continned investigations, by carcfut and experienced obser\vrs, tlat the exact relations between cause and effect;. cain be ascertained. Among t:he symptotms that slhould direct attention to tlie eves as a ctiuse of nervous troublt, imperfect or painful vision is, of coilrse, 1prominent.'Tlli s ptonis of astthenopia, if -persistent, should always suggest a possible.refractive errort, o musculalr meo-ord(imnation. It rarely hltappens that nervous troubles distinctly dependent 11t)po eye-:st:rain obt ai withou t definite eve syvnlltolns; but it is not unconmmon to. find the nervous symptltoms Ixtuch the more promintelt. In any case wberc the symptoms of eye-straitln or asthenopia occur, no examilnation can be contsidered complete uitil the eyes and eve-muscles have been subjected to a thorough and comprtehnsive examiniation. 1F. lP) T. ] C(IAP t.1 X X I. LIST 0V A PEIW INTERNAL.!MEI)IES WITHi THE fOP!THALSY'1 PTOMS Ot? OF1 TU EYES,, FOlt WHI ClHt THEY HAVrtE. BI:EIN FO U NI) USB':EPU,l IN MY PAc (TICE.:, TIE listi wh iliclh follows comprllises mrelvt tlett remledies %which l ve been adm( instered from itndicat ions fiurlishlld by the eve alone. Others hatve,beenl found lIseftl also, bult, they have }ben selected on taccounlt of syvnptomIs atIart; fron tlhose of the eye, an1(d Jfo surch as are fannilitar to al gnl p'1n. I I Ittrac:tiit:ionltes. Mallsny reetuttt(-ies a avi ngt l st ro.1n atlfnity for th:e eve, jl:dged by their'pat-ho ettnesis, haIve not, in lty experience, been foulnd reliable. TI d diseases s or svytnl iont given.I telow have iee n repeatedly cured or relieved by a single riemedy,:t le namel ofif witlic is p1laced opposit each group.'lThe dil tion or tt itr'attions used wt ere the fir st, second, or third. ACONITE. itnt. the earlyv stage of inflaunmlatlions of the contjunletiv-a, cof'nel, atndi iris, antd after surlgical ope;rations. ALtX UmIxNA..It chlronic blepharitis of adults, aid in blennorrht.(at of the lacltirnal passtage, witht tht iti dsc.iatge. A tst;xCTs. In suterficial and deep-seated uleeratidon of the cornea, especially in scrofulous subjeets. Catarrhal opht t}hal rlia, with thitn secretion tand irritation of the edlges of the lids. 1.lcetation of tthe tarsal edges, with ttin secretion, antd 1in opht halnria scrofulosa generally. INTE RNiAL, 1E-ME DIES, t.I ].: IlA, ONNAs.. In ihotophobia; injec.tioi of the ocular conjunctiva; con)gestion of the retina land optic nlerve; dilation of the pupil; cl iarv neuralgia and tpai in thle opctic nerve, with conges tion. Neuritis optica (diagnosed with the optthaholta scope). Scrofulous ophtihaltnia, with great. coitgestionl of thle conjunctiva6 and photophoblia., BtlYONtIA. Sclcrtitis or eplisclfeitis. Rthe natic Iritis. Conjunctivitis with soreness of the eyeballs to the touch and on tmovitn thentm (cocaite). CoNIsM.t Plhotophobia in scrofulous subjects or in. scrofulums ophllthallnia; keratitis., ( uCAT.s..flypertinia of retina and optic nerve; optic neuritis..Astlientopic syn'ptom: in conjunction with a tent entcy to conf est:ive eadacthlte or ft'uslhed facl. Ci( xt t OMi t i A.X. C iliary neuralttia, est peially in scrofulous or purulent. op}tthahtlnia of childtrctt. ( ls ti t xN. i., Accommodative asthenopia, with the usual subjective s ymtoins. i)ilplopia (fromt functional disturbhanceof taccom0ttodation in one eve). Ptosis from partial paratlysis (Ch rotnic spasms of the orbicularis. MAtuscultar insutliciencies. Nictitation. I lpenra.stletsia retin 0at, witil plhotoplio lia (nux vomtica). IRetinitis, Gt,{oNoli^x. Vettous hyperlatmia,o or congestion of thlt retiat tand Optic nerve..if['AtAr -s i.tlt or sulptlide of alciutnt. Purulent ophlit tlllnia ntlveiterate blepi actitis with luruilent secretion, in scroftulous subjects. Keratitis. Contjuntttivitis tlerpetica. I v"- >lr As'rt:N. IXt acute catartrhal optlttaltmie, with profuse discharge, especially in serofulous or ill-nourishted sullj'ect tIO:)> f, or POTASl'. Inflammation of lal]ryttal sac, witlh miucous discharge. Syphilitic il'itis, chorfoitditis, and keratitis. 1 ION, firrumt imettllicumt in different prt'epia'ttions, int vuarious ophthalnmic diseases if 1anmla n:ic conditions are present. MEiCt:c Y. Blephar:itis, elrolic or otherwise; pulrulent oph. thalmnia vwith coplious discharge;. ke ratitis diffsiusa, superlicial and deep-seated ulcerationl of the cornea'; phiyetenltar 382 - INt EibNAiL IREMD IE)S. ophthalm n tia; syphtilitic diaseas of any or all the different stlrcturcs of t}oI (vc;,!piseleritis; scroftltorts olphtbalmia, with photo)phol)ia. In order to e' t a local effect of this drutt in scrofutlous oplhtlalmiia! somentines use an eye-waslh, mtliad otf (on eighbtht of otne grain of p!er(chlori(d of mercuryt to two 0.ounces of water, Nu x vo. i:cA. A stentoptic symlptonts. I )hotophoita from rtirdal hyvperasthesia. l)ilatation of the pupil from spinal irK'itation,. 1)iploptiat froml inu:ular asthe ntelt pia, from1: paralytic strabisms. Pi:aal;ysis of sixth nert ve (rectts extlernus)..I01tomonyious dip)lopti. We'tcakeictd ptower of a(tccomlTimodatiion in one eve fro ut, vetr-xettint' it. Severe p)ain in the eycs, aind during the 1ig lit, wtitl conjt 1 | etiva l i hjection. broug}lt: on by over-tuse of the eyes, especially by artificial liglt (gclsemilnum, mcre(ry). ) Splasmodic or involuntary closure of the eyes in adults (gclsemninum). OPt.)m H1 yperamitna of tim conjtiictiva and btorders tt the tarsi, with injection of the ocular conjunctiva in coneiicction with co1ng(Cestive Iheadache. P' L8i i:SATILv,. Catarrbanl op)hthalmalnt wit l mucous secretiont. P'lIOSm: Ilu01. e tinal hnypcrtrmia with cotngestioni to the head. Iltashes of light, dazzling pointts, or rintgs of variotus colots, before the eyes, iindicating extreme sensitiveness of the ret ina QuxvtNIIx,:, 1st. trituration. Asthenopia, in dcbility; and in eye aftections generally of maltarial origin. SANXort;nAl A, lRctinal congestio)s, withl tendenDCcy to flushied face and eong estive thead:aches. Sucperficial ilnjcetion of the eyeb:all, with feelingi of soreness. SANTroxiNN i, Asthenopia, especiallyn in cases where thiere s evident loss of tonte in t(he retina and accenom odative apparatns. Such patients 0do not see q(uichly. SovTer. LAF a., Spasmodtic twitchiiigs of th e lids (gelsemitnill nux vomica), SECALE, Asthenopia. Asthenopia with enlargred pupils, due to nervous debility. Diplopia from muscular asthenopia. EIXTERNAL ItM E. MI}S) T. 888 8 1O'e 1BLIA. C (onjutnc'tivitis and iritis it children, particularly lt those of scrofulous diathesis. (Coglesti(oll of the t ilir;:t1 vessels, as ilndicated by the pinkish szon:tt around the cornea. Severe pain in and aroundt the eyes, and on moving them. Severe phottophobia fl1rom ciliary r'vous irritaLtion, STr LL Xt i. NAsthenopia (clmracteriztc d by debility rather tlhan inf aimlnation, or imarked irrtitat ion f tlhe taccon odat ive tapparatius. Astthenop.ia from genfral debility. Sc;l, I-lm tn. In chltromi ophtthalina scrofulosa, with superficial core itis, thie ptikish zoue wll arkcl ed around tle edge of the cornea, and photophobia.'AIRTAit EMFTI'tC.,'tl}lotophlobia. in stcoftulous oplthalmtia of clildren. Piustular coljunlctivitis. Zt C M. Retinal tasthenopia. A. nasthcsia retina. NeNuritis opt ia. Acu.te retinlitis alntttrit'a. Brigltt's disease (arsen ic). ZINCx.f XC I IOSi X'IATB. A fflectionsof thel retina nmarked; by gr1eatt irritation. lixrpersthesia retinl., wtith photophobia, flashes of lighctt alnd luminous spectra (zictunu, nux votlic'a, gelserminuii, plhosphioruls). E.XTEI N AI I E M I;) IS. l'he following are tiho-st thatt 1 havo found most satisfactctx il pr}ivate ptt ac:ttitc....... THE )IYI.)IlIATICS tret of COurttse, iiI almost constant 1use. A/ropine suip/ate is always to be used in iritis. See pages 161, 168. D)tuboisin may be sIulstituted if the atroplinet causes irrtitatioifn, or aftit.er a timre c tauses what: is caltcld an atropie conjunctivitis. It is used like atropinec, of tihe strlenlth of about one to four grains to the ounce. When used in strolgter solutions itn imav affect the btrain untplcasantlty..In a stolutiotn of 1 sixteen g rainst to tlhe, ou0fnce T. found it to )prtodue a miild delirium or intoxication whvich lasted nearly twenty-four hours. T1ere was an idiopathic 384 EXTIERNAL REMEDEl)l S. cont taction of the pupils in an elderly lady, and a s atropine produced no effect, I wished to try at more powerful mytdr iatie. It had no efftect onl tihe pupils. tfmaittropzne hydrobromate is convoeien t where a temiporary effect, only is desired. It )paialyzes the aecot immotdatiol, itut not always so persfectly as may be de sired See page 169. If, therefore, we wish to produce, a miortet positivs effect oil accomtnilodatiol,,we use atrt opt}ie sul phltate. Even this will sometinmt s fait to perfectly paralyze( tYh c:iliary mlnuscle. Tli effcet on accommlodation with either oft these sublstances is ore certain if used at tfrcqultent in terwvals fort a day or two before making an cxllxaminatiot of the state of fthel vision, For rapid fflect on accommodation, it }tas )een proposed to ust a solutiotn colntainitig two per en t homattlropi n and two per cent coc'aine,. The nattxi1nmi effect is obttained in 3 0 to 60 minut(es butt soon dctlines. C('caietf muriate as a mlydriatic is us.eful in oplthahnoscopic exas natt ti(onis. A two per centt solutioli enlarges the pupil in a fCew mintutels,: and the effect passes off in the course of lte dhay. It increlases the mlydriatic effect of atropin when used with it, rhetce it is useful with thle tlatter in iritis for this, as well as for its analgesic, property..It is used also as an aid to the action of eserine in "glauioina, As an aml sthetic it is available for tnearly ll opt rattions on the eye. I 1have removted the eyeball undtr its anaestlhetic effect without incolnvenienlce to eitlhcr pat ttie t or surgeonX. I [)owevert in sutrgical operatiolts of long duration, timtimid patients do better lunder ethler. The proimptt t relief oltaitndc byi it in a case of neuralgia of the eye is given on page 23:.'trtn 51MYO ICS in most frequent use are et cseriAn and pdi ocra ne,.Lserine for glauco:ma, see pages 171, 191. Its effects in reducing tension in glau tcoi' mt are sttluppos(ed to be ilncreased )yv u8sing cocailo wth it. In sluqggish corneal ttlce ration it is used also il coniljunrction with coc(taite.'lahe o solutnion for' use in glaucomal should be, weak,: or, grain to the ounce, or it mays act too enerfgetically. EX.TENAL bEMEDIES. 833.Pidtcarpine acts similarly to eslrile on th eve butt multch more weakly, ian ed is use in a solutiton of two to four gins to tlhe olunce. It, is less t irritina thtan escrinct, and I ttherefore use it mtore frequentlly ina tthe m.ydriasis of a tst-henoplia, It contracts the pupil less quickly antd Icss focit fly than eslrilltt and is piretferred for this reatson, by somte, int gilaucoma.. For sulbutaneous i njecttion, in old scletrtist, ke ratitis iln gonutl or rtheumatic subjects, and l it clioroiditis aitd retinal dttacht lent, it it s used in t a solution of: alout four grains to a driaclhmt of water, threc drops of which are injcted daily or less oftent I have usually given it.b the mouth), in (tosevs of about orltne tenth of a grain. ANTi-SX EPTICS AND ASTI SINGESTS,.Tftrafc t of fsihtter for use i itnftectious diseases of the eve leads aIll otlier substances. It is spoken of t af est p 98, I g, 1 0 11 2, etct,,'as a p)lreentive of b litdness, used as a disinfectant for mother an:di child in clases of conlifnettleni, it. is noticed at page 108, in upward of 17,000 cases of this kind cofl lated by Ilowe (Tr. N. Y Stat Stfeo.'89), 8.66 % of disease occt rred wt hre these measlures were not taken; butt only 0.656% of disease was observed whlere ta drop of a' 2 solutioti of nit rate of silver tfor disinfection wats fmade use of. i]i'chlorid/e of mercury may be used like the above, for the p)urpose( of disinfecti onr itn a strengtl of 1: 5o000 to I: 2000. it tlmay possibly be used somewhat strotngxer thanlt this, iut a theal thy eye is intolerant of it at 1I: 1000. A solut tion of 1:5000 destroys germs itn three minxutes, and on(te of 1: 10000 in about five minutess Chlorine water, when freshi, is the equaiil of thOe bi-chloride of metrcttry as a gcrmi:idc I t'formerl used it int pturulentll ohthlttial, ttbutt it is very unstasle, and I rarely recur to it now. Peroxitde o^ hydrofYge is atn cquially reliable anlti-sep(tiet. I have hlad no experience with it..1toracic altid ftur to e iht grains to the outce, is ustefu in all formns of colnjunctivitis, as Ia mild disinfectant. olarLx, lbihlratle of soda, ten graltins to the ounce, is chieflt serviceable it lyperat'inc condition oft the conjutnctiva, or ill mild c.on juntltivitis, Su"phate of' Zinc tt.t / sulphate of copper, in solutions, I. use tvry rarely t present.'lhe latter in the for m of crystal 1lmay:: usedl ct:autioutsl ill toutlchint,' ranulated lids with trachttlomatous Spannl s. See tIpage 1. 9 (Alum, im terstatl forml, may be frecly umsed for grt.anular con junetivitis and is oftetn iprefratble t t the copper, tas'ausii only slight react-ion. OCti itrum atlminate my be uscf: d altso in granualt r lidts, and in crystal forml causes less ireactiont than the cuprulm sutlphate. f.requently a five to tenl grain solution of nitrate of silver painlted on the reversed lid is more effective ttan either of the above, UN(O UENTS, Thle tunue1tnlits /t-t&t-'h i[ hat 1lO(t' haost uscful are the lf — tfed oxide oft mercr,'/, in blepharitis, s(ee page 281, and the ci'tine ointment (ntit atet of merelury) in the stamtle affec tion, about one p)li t of thle citrine oint tnenlt to eight parts of vaseline. Other unguents are mentionet d aso at tagtc 28.t Yellow oxide f q' meruelr ('tagenstchlerl s ointienlt), in tihe strengt:h of two to fotur gra ins to the ounce of vatseline, I have, used occasionally to advantage in slulggish ulcerattiols of t:hel cornea, a asmall portion tbing inse'rtcel between the lids daily or less ofteni. It is tbettt'r lborll w\ithin t he eve thtan tihe otlier preparatiolns of mercury. B ) cy advises its (preptarattionl with stpermaceti ointmen(t, with a. few drop:s of olive oil, ats less irritatilng to the eye.'Whnt(l indicated, tan eighth of a grain of attopineo can be added to either of these KOCH IS llE MED1)Y IN EYE AFFECTIONS, Konigtshiifecr (Stuttgart) reports 1 the result of treatment in ten casesS, with} K(och's remedyt. I four cases of cczenmatous O)pthal. Review, February, 189t. E:XTERNAL RBEMEDIES. 837 uleers of cornea in serofulous childre n, and in two cases of tubercular disease of lids, one of interstitial keratitis, tIe effects were favorable, the corneal ulcers healitg remarkably quickly. In three cases of iritis no results were reached. I have remarked at page 169, in speaking of strong solutions of atropine, that caution should be observed in dropping them into the eye, lest cerebral disturbance should ensue. It must be remembered tlhat liquids of all kinds, when dro)pped into the eye, reachl the throat through the lachrytal duct amostt l tas readily as when taken into the mouth. I think that tihis work was the first to call attention to this fact, and it would seeml to be one of considerrablel importance. A ny one who will take lthe trouble of testing in lis own eye the effeet of a few drops of a solution of twNo or three graints of iodide of potash to an ounce of water wvill, I thilntk, be surprised tto find how soon he will get the characteristic bitter of the tlkalki in the throat. T lhey alsom enter the ciriculation by enllosloosis through the cornea. I had long noticedt the favorable t c effect of a tcllyriumn of attropine (one) graintl to te outnce of( waater) inl the photophto.,:bia of scrofuloust ophthatlimia, before it occur'red(1 to me that: t::he intteratl effect of the:belladonni a might be, at least partially, the cause of the impruovlcnt. In jrescribing collyria for th ie cye, we should therefore a ttwa-ys tarke into account the: possible, or perhapt s we tmay say the iunalvoid.able, internatl ifftets.,22 'I']i.SA1.' P'E'.Y X.I'L: TEST TYPEi it: fir.st- sePrics ofi tesat Ity p i p''stet d m1rely as a C(Icvieni(iiCei e ilt tttf oiltli' thO stftte{ of( the visiot, withl ot' willmltotl g tlasstes fot.r reading or1 near oba t.jects;.'TIhe dtlfji:tttt siz8ed print tl is nitnilt l'edt so that t record-t st:t il tt ilttade ftttntrom- ti1e tot tinel antt( t1tI the' ttl 81 Noiitsi, npoe-illtt. t' orialiti tle..it' it ir \\ e:'' (tvit('l.' power a''t1 i el detelmit ed.'11T)8 secott01 selrit'es, 4 tt tt: of dittlereut sit td gotht totteis, is ii eltotftilenield 1 fo ti1n ot trl't Itxact 1.11 tSreittlit of the ati n il's teiteness olf visiot.'The Intttrllbt s il this Sr: tieS s 11xtiedicaf the d istanet n at ani teIlt a lllllatlep leve shtould dii t ristrl. Ihe let Itet'r,.lt e lett's:tf itNo s11o.1Id Ih 11an1111 i red1adi l, i good lihglt, at six feet, 1U0 at tI::en t feet: 0 at21) teweattl le,: tl. and N. 4:):1, I' N'o, 20 canr le seeni 1l)8y! a1s otar a'1 s f tent f11 11 leet, tfthen \V, =.. i.or' ey..e is(1 en tot pi0. Oc,(eeasiona 11l a p.e1rs will he met' i-t! it:'.;>.:t:''!,~ lStt':,::.: l t iw~:?{:t ti:ct:t:7I:'l:t:'~.~t' V t.)......ft.. wi'th o clant tet t: d the. lett s a a 11c10.t 1 gt'eat \ is 1: tc', l ttl 11t1 1 Na' t l tt.t anl ld t vei t't t t it'o t'ig'ht is fa N. oriaht le ftr' trIe di tt.' thetit t ('a gilret' dista: e t.alo. TIt =second== ='e8i8 c1 )4:espon t.114 s tvery' nea'rl tI o to he sysst e:t ot:1 Vot Jaeg'1 aIt S-e I le. thttt is, the' tell a. i of en. t t t t l::lO p ic eye.'. TIRST TSERIES. No. 1. I 04t3Aa 4t s L a I tt t+ V 4 1 It:i: Ttit 1e t9-, V' B'. f:ysr.f-!J n-:. A Oid. r lvn ae t-x- z.ele.: It tti^e: wlt n~ > ite- -ittt jass a I fimeta t-ostt- Ssa' aass s-If t-~z f ^~a ysis ~- s-fs l 1 as~ <~~ eniastae s:.<~r xc-^a^ t r -*, ^A ~~. ri.. et s fll;tuhl ~ t t i ir* l ea its sexa't- ti'^'. Watt 1t sai s r-t r f tata- g) ti:s:s- ta Isa t ti:n sS- i {lftn tstae, I ts a a svtA - d t oI:-t >>:'I), tat tr iDM s st ia??aleti Ies rA ltft^a a -la^t a Si p- t t S satid'i t -- a;t't {my i a a ie ita, itfat la-f rata s-:a$ triy p2> v9.i^ Ht~n~ F'- t:e tkif a e xit t m) X ~. a t F5^, ~ - >>te o2l ~tse t.ity e ^fit ~^c:~!3 y.- i of{ e w5 O ~ 85 <-a e <. t -a.ttsia, I aA-jf:, a>- I f-E 7 l t to!f:i t; a, its 19 Str -t. es ri *a sr. a t ~' s s } <-f I saaa ai4t~!i Ca*aCt~ a a Is~ s tj i hale itas f~, to a;y~-aias-ietar fi'sta t, s.al -a Is d'tsass -Jit a -l^t2No. 2 tolleet.s- the alerle':.s ttli-e atih holid your gaondeola to shore, at alWmet to do yl yea a sert:i nsdt notle at a.splte:aare, tand prted r- nt to be abandonaet svwndlatert^,''te Ve ta:,eaia l faIt theta grsanlsfste, ot ert^-tateeh ts but t as yet IX t t s ktot thlle ns3 ame or i.te ta lrt.sps of tht s p:;atlseriao, at tha $B.aa.ion butat teely.:f a thaIt the hai tbhe Veatiitt sey foer color: itn thlt ditfibuti6 sn Almd a'raSnRugeatnt of or hit f -'agiacitt:s of dret.s he htatd )ttrodue<'lse w:ttsrac-Eutlo ect.s of rea, a as<,te ^.,t attougeithtear a: tultirota s a t'it.r' a., ay. fti'etnd of btigSant.l avosilsd ike to ateet s a ltonasly plt. es i fie did not cftr to stabf. e ant srla my btoaty iaa s: a t ir.aat C:seM, as., his all Venaetht:w No. 3. k3eepisg, I felt that lhe otught to have sdoate bIt tt he ijlI))ortcd t a tI alms, asid I htardly know now whethaer to exult or < i -4~~~~~~~ -----— ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~ ~~~~~C C. I + ill -1n IN DE X. AirlwxviATmiNo and signs for lentses, Asthenopia, spectactes in, T4, 75, 70. T9. Astigmatism, 76, Abscess, of cor-ea, 13, 18 compound, 70, 79. globe, 176. diiaginosis of, 77, lachrymln sac, 29 irregulatr, 77. AccmPtInimo datilon, 49. mixed, 77, 81. anomalies of, 5 1. regular, simple, 76. ditffers froms refraction, 50. spectaclts fsor, 8. mechanisn of, 50. test type and lines for, 3-48 tparalsis of, 2068 Atrophy of optic nerve, 218. spasm of, 269. field of vision in, 21.9, 220, Acthromatism, i3. not: untiformly fatal to sight, 220, Act of seeitg, 20. ophthaltmoscopie atppetarante of, Amatmrois, 18 etc.:1, 219. rAmbl}yopia,'22. Atropine, action of, 108. (cat es of, 2424. "ani aid to dliagnosis, 28. diagnosis of, i222, strength of solution, 159. treatmlent of, 224. use in eye affecctionts, 161, 16 An }tatomly, 5. 169. Aihyvloblepliaron, 309. Aut-otlptaif mosco pe, 40, Anterior clhambetr, narrow iu infants,'23, Apf akia, 2A56. BlN. ) coipre t 86, Apoitlexy of retinat 206. tsiept, 3 Aqua chlori. the use of, 123. I lloadlota, its internal use, 331. Atlqueouls huttor4,I, I, Binocular vision, 21 iAr'utts senlis, 8. Blephauitis, 20..\.gtcn, nlit., extert al tse of, 95, 8 1 lI00, t Bleptharo) s, 280. l05t, 107, 1X:, 112, 120, 132, 118, Blilndness, sixmlation of.7, 335.'rights di sease, 203. aus a propvly lactic, 108. Brvonia, use of, 331. ths ise of, 3 0. At tici iial eies, 259. p:tpil, it64. CANAr, otf Schttlt 6. As^ttthsn opia, taccoi)rniodative, 79, of lFontlia. 6. Iusilcular', 8b. Canaliculnu, obsrtutictins of, 291. retinal,'280. anatomy of, 17. irmedi es in, 76. to slit up, 290. 30 IND i)X. t'alt'er of tth eve, telultlary, 303..toroiditi;, 17. (Ca.ipsiutar cata act, 2Ya3. amet opic, 17. opacl'tits, 2.48. central, 1 t4. ('tttaruncltl, 1. disseiinlated, 172.'ataract, 20. opht hiainoscopi aiipperanc e of, caes e of,'28. 172, t74. complitt ionlls in,:'237. siplext, t7I ditanlosis of, 23. - suppurative, lUi. by lateral f uillninatio, 2360. Chronic healche I ned of oph ithatlInofb opth:tilhatotoll itt, 236. scopife tex atin n tioni iM, 47. objeetive syviptu}iis ofm 23. Ciliarv body, 1!. prog:t orsis i., 2 l.1. mutt e, it sul ltect vce s mt >tti oml of, 2, nerves, whelt rifpe or voil' te}lt, 240. ti)r esit ^ss 1 tI. blaie f.59. Cliary s scle, act ion of, 4i. iaps)I\,'25i. division of, 319. capi"u o-lenttt ictnlalr, i24t psaralvisis of, 2t8. eol gei^ ilalit'249. spant (}f, 2;tof~. e tica! d t. 2 C tlosn:i. of pipililt in iritis,.10:, etc. diatdvti iv, 2. after cataract operait o}s, 247. ittit, 23;3J. ope'ratiotllS forn, 1.6. lhari, 0. Coalne, I T, t.t opS rat ions for, 2.40. Coll yt a til conju1ictivitis, 335,;536. tfter treatmrent,'24. intrut la efiei t of, T7. aXtieltliiat,' )t. 1Color fiti ifl hne:':<, 2i, nullclr~~, 2l. tColor of tlens,! i, pyramda5:l- ~. C'oical cornclh0lea, i-l(. secondar., n4i8g.xt' s oix of^ I 4i. -chniltle,:;>V9). alrtificial ptpil il, 147. ioft, 2- 10. Con liil +ju nicit tiva, a feetion}} of,,4. ol:erat io,,) l for, 2-I0. I atatomt of. t. striat d:, 2:v y fsts o', I;. tra niatict, 2:,. foreign liidivis in.;0 7?. tr atl noIt,of ca':trac, it. edical, i. niujiti' of.: 05 2:4tyt. 3 t warts, if.I: dici. -ion or ab-o:rpii onl ll 20, Co tinitl ivitt I 95. extraction ph itfsi: le,' t.>. c eatarrhali, 97, flap tt'ex tr iit oni. tit 2, liiell ital, tt 3. linear <:,xtractio:n,:TO-. di:phtherivti, 114. iM' ripliv(. ~r~ic~l-f tlt,:t incari s L: extractionrl,243:, eruplt i v e, 1f'. r-clination,' l 45.' exantlhemattoll, 1.31, -uitiont, 2i t.t fi. iln I iIut iilar, Ilt C'.Mataract Hgla-sss, L. 4S ))oi;rM }l{:ri lI, l {0.q. ( "atl'tarrhal, )If{ til} iiaT i ff7i. rat r,, t It. t rIatl tof. i8, 100i. 1ttPl: tl(ntul}at. f it I. I Chalalti oi} i, 4. t t ru lt,t It). Ci tortoiil, at of o' f, 8. is tflntouit, t. itpt;r mZia oft, T7'2. simpio, 97. ftarco a:-f, 2.l Conl agi otsnes of oi)lSitial;- nia, 10it, Choro^s~iit, tu-bercles o~f, 178, 1.^ 18 IN DEIX. "lt'o.vergetnt s' rab1ismnu:,? T). 4 )ilhr..ation of eltS, n -t C:Orlv sis, 1;02. Distance, how etermtnined, t 2~,'4c41n 4, aliti1tcionsc of1 It., Divergent;stJ.rabisms 1?2, abs)'cess of, t1, 148. ivision of ciliary musle, I02 abtnasions of, 3, Ioubl e visiont, o, 8 7, 281, 1t, 2i,5. anato v ol, 8. i Iropsy of tlhe ev', 404. 4o(114t, 1 4. 44 4b1isiw, t148, O170:t. 1haziness o 2, f12,, 1 340, 312. injuries otf, 31, lack of tra nspi) re 1cy of,.. " 28. o')a"cities of, 1 40. f 11ectric liglt1t, eittets of'; 2' i2. pa4 aceu tesis of, t140.. Emboli sm of 4c ltual arterv of retina, p.rforation (:if. 4*,. 2 I,2.staphil't lna of, 1.4 1c 1aloid 1i sease. 4'2, u t1ce;s of, 1i4I4. E41cry;sted t4 lm',r4 of lits, Zs8!, cr1tscnItie, 1112, 415.1 antrce of optic nerve, 15, dcep, 14b. Enlropiunm, 28:1. su ri'errtial,13L'ucI.11t.' }mchat ioll i,' tlKe.i.\ re T ~;7, tran1 nsI,are1 t. 1t 4 t.. 4E4tica n4t hu.11'p4., reatnment of, 1.li Epipho,,ra, "L..;'irossi( ldiplopia, 2i-,'265..Etsvch'riki -1. 5, Cro ssi of optic nlerve libres, 14, Epithelial, (a11tt114 of lid, 283. B:0, l tuilitbill-mo of muscvlcs tests f-orA, 84,8. ('Vstatlin1 e mles, 2. 1E. E'r il', u of' 441. 4:44 4. 4'Vclitis 1. t, -, 31.s1,"h:i, ('vst'.i rci, ISO4. 4Evi' eratio) t V, 21. Cts of iri1, 1. Exam inatl ion of tiH eve, 1. of Hlifd% 238.. 1v l4ateral 1m 4irni atio', 4'4. l ht <~lul lnio; cojlfi',;.~T, i:)4At. hrtlYltt1 441 it::ii, Ex ion ofI t14lt-l, 1 4,. 4Deta 1usnes of retin1, N8 1of ttaphv'. 411. A[t 11 Of, 44 104. Ex1atio4.n of n:erve's of tl 4 eve. I*, D)iaabetie tai tat. " 5. 1E Exco'riationl oft he (sr, fH i. 14ila41te1d i' il in ise'ts of o,y44 1' 17...ltxoIphor t a, 8I). 182. 1 8N: 184, 8IL,:1 4 41 Exo 4l1111ntos4:I{. Dioptric SvWtit'l' (of lens"es', 0t;0.4) Ex ern4l r1e441 ie.ics,';4;, Ipith4eritic conjunctiviis, i 4 4 Extractionl. See:;. IDiplopclia, 35l 85t,, etc of foreig/n bodie fromn tUK- eve, scope, 41: 08. I',:'. i!iseases I,)f tle etye cotexist 4wit4h di:s- \I E'e prote''ctors. 444 4~i~l~r- t 41114 1)114 H, i.:14... ~ 1.'l ic 4;.'4../ease of the. brain, 40.:.2 - 4. Eyeball, Sec (;-'. co, ex is4t with i1ns1: ity', 47. Eye lashest rem'1i(val o. 2iS. 4n4l:4oss4lidi t4o dliagniose form,11rly, 1 Eyeids, a1lt'ec4tio'11s o1f.4 H:.81. I44-. a4na1t4 o4,4 4 f, 1 i;. 144made1 a sp:41cialty ly ltile Egyp- 44 elpharo sp1a'", h841, tians, 1. d1 1tieha-is, 1.'1.:e~ess~ary i, foplcl'e i l. i'O for.}en- c.tropilon of -. oral I pr4f act 1ition1e1r4s, 3I3. c pe o'tr t'i(:4444 4:4f1,'241-. 352 INDEX. Eyelids, epic)autltis, 28 5. Glaucoma, premonitory syvmptot s of, hordeolum, 285. 18'2. paralysis of, 286 prognosis in, 195. ptosis of, 287. secondary, 198. sp:asm of orbicularis, 280. treatment, 190. tinea tarsi, 280. strgical, 193, triehiasis, 283. rationale of iridectomy, 100l tumors of, 284. when to operate in, 194. wounds of, 305, G tlioma retirte, 211. Eves, artificial, 257. treatment of, 211. to insert. atd remove, 2 59. Globe, affections of the whole, 302. descritption of, geographically, 5. foreign bodies withil, 310. FA~-sinTr. See.Prt4'yp tension of, to (determine, 28. Field of vision, 31. Goitre, exophlth'dta i, 302. to ascertain the extent, 31. (.Gonorrlihal ophthahnia, 109. in atmaurosis, 213. 220, 2L 2l Glranular ophthallia, 11.t, etc, in icataract, 237. treatment of chronic, 118. import.ant to deten nine, 22'), 221. Grave's iseaste, 3;02. Fistuula cor:.nea,'24 7. lael'irv? alis, 291. Flap extr action,'it 2II f i Nlss of globe, to determine, accidents in, 24-1. 28. Fluid cataract, 253. itt glaucoma, 182, 190. tFluor-escence of tens anld orneta, 22t. e1 tladacle, lneed of olpithalinoscopic i:,,ontana, spaqcee of, 0f. e xasiniation in, 47. F'oreign bodiet in t heojuntiva, 307. li, lenieralo:lia, 28. in fth cornea, 31t2. 1 femorrlgage il the antl chamber, 314. wtitthin the evetba;ll, 310. into tihe vitreoust, 3f1. Furth nerve, paralysis.of, 2.00. under conjt ntiva, 13,3. l'ovea Ven tralis, II. Xepar. silph}., the ute oft 331. Hlerpes frontalis (seu ophthahni ics), 282. (h;~:sit..i:ro, thle u-e of, 331, t lerpetic op ltlaitdia. See PIt^ycitetnual;tatoma, i acute intlamm atory8, 1'2, op:l/tha; ihit, 183. I leterotporia 89. eh toiti, 185. I tloidcl m,, 2i8i. tclco d ts l. a ry,:}8. I vat i i 178. dansgr tf de lay in olteratug for, It taloid lt nlt ln'a t 13. 1i4 i. d 4drasi n, the itue toL 332, earlx' svmiptomu's oft 182. I /!droldutihalni,:i0. sexavation of neirve in. 187. Ii lvperini of hor:iidlt t 1. fiit, inans of Gut ef itt, 188.:i t:jeCivai, }i 4. i:rit hdeutoni",. i is, l S >. mnedical treatentti t of:,1 l). l opt i} nierv, 214, ilciraxlaict pain in 1, 1'2. reta nm-intllaminati,:ri 119, llv iru. t>-{cliei n: e, it 0,. pht i hal mo pi l ia;o' f 181, ll I y per e irit ia, 04. perations lor, 193, i 97 l a ihe:tia in, patholov, of, 107. I t dia no'i. INDEx. 8$3 ltypermnetropla, spectacles for distance is, ( diseases of, 145. in, not to be prescribed tunless pithelial covenrlng of, t2. alsot lt:elv necessanr, 71. I ernia of, 1i3. treatment tof, 71, 74. injuries of, 6t. ]typer)horia,t 89. prolapse of, 103. I typopion, t 39 t renulous, 171, 9.56. lritis, chronic, 1.:3. cause otf 160. l1'ir rL Mt E.TS and instrnments, 33. diagnosis of, O9* Infilamtiattiont of clhroit, 172. serotu, 18S of conjunlttiva, 95. suppurative, 156. ciliary bodtt, 31. sypht6litie, flo. corntttia,!;. trautatic, 311. i tis, l bi8 treat mlit of, 101. lachnrymal apparatus, 259. Iselmina reti'Viic 212, litIs, 2.80. optic nerve,'21, etc. retinta, 200. K iRArTITIs, 1.34. seler(otica, 142. bulbous) 1360. vitreous humor, 178$. deindriforn, 137. vwhle eve, 302. tdiflfu'e, 138. Injetitons of co(ijuneti va. 95. fasticullar, 134. signifitea le of differentt redtness interstitial vascular, 137. of the eve,,, 5, 9, etc. non vascular, 137. Injuriers of conljuniti iva', 10 i puntll ata superficialis, 138, cornea, 31 t' suppurative, 13 4.1 of the eyes, 30I5 vascular suiperficial, 13. globe fri'on gnlfpowder 3r07. vesicula r, t16, froml pterie ssion a 1, t tie 311 tratient 411,0. of iM ais t tents 313. Keratto-gtlob, 302. lid, 305. Koch's treatmet in eye affecti ons, a36<. shlerotie, 315. svnpatlhet ic opitli taliiia, froi, 310. ILACtn vt appiaratus, affeetions of, internal reedties in eve affections, 28, 8330. enpipliora, 289. titervaginal space, 15. gland, ait toniy o:f, 17. Involnittarv oscillations of globe, 209. diseases of, 301. lriidectoti, the operation, 1i, 193. p, passag', nitoiv of, 1, 300. iit cattaractJ, 2 i. obst) rti:t ion of, 289, etc. choroidl it ist, 0-, etc. ca inaieul, 21i.. conical cornea, 3.19. duet, 297, glaucoima, It93 sac, 201 Iridiodesis, the operation, 1605 bleinorrlueca of sac, 294. in Saitaract, 251. l stitsa of sac, 2924. conical cortsa, 14l, sf'riettre of, 2(9, etc. Iridodone:sis, or tretmulous iri', 171 treatmnlen t of 7,. etc., Iris, adhesions of, If l0, 161, 12 S titling's operation, 299, amntomy of, f12 Laop filtialt os, ~28, boim)st, 1t0. l',a onmiia c ibrofitsa. ti yts tof, 1 71. f, Lateral illunmiinatiot, 44. 23 P)504 INDE)X, lakteral illumination, il cataract, i230, N i,Ai duct, 10, 800, oix'teal opiacities, 27,1 0. Neuralgia ocutli, 23I, d4islocation of the lies, 25.. Neuritis descert ndet, 21 L.u ns, affections of,.it Neuro-retiniti, 213. anatoniy of, 12. case of, 21-6 dislcaltions of, 2 -. diagnosis of, 214, 215, geographic)al iv ios of, t teat nt of, 217, etc, v^lwounds of, t21.; 31. Nictitationt, 286, Lfucomai of' corleit, Il50, etc N ight bltiidness, 2)28. Levator talpebr11tt, paralysis of, 260. Nitrate of silver, u1ce of, 120. Littme, injuries fton C, ~i iin granmlatl, ns, 20. treatient for, 300.1 pturlent ophtlhahni al, 102, 105,:17, 112. XiNx vonic, iiiteraii ust of,.331. MAtc::tOTi', the utse of, 33. Nystaglms, 269. Macula ltt ta, 1,1 2t. Ma1t-}osition of thi lis, 282. Meibonmt i cysts 8S OltiEC mxni' exa} mina tion of eye, 26. glandts, It; Ofbliteration of laich. sac, 3.15. Mercuiry, in disease of eye, 331, Obstruction of lach. passiagea, 294, externally, 130,.331, 336. etc. Micropsia t 174, 2 17, 2 2 t. Op[acities of cornea, 15l.'Mortar, injuri, s from, 3106'. lens ali (a pule, 23 treatt ent t of, 30. vitreous, 1:78 Mules' operat1 ion, 32 1 ( )phttlml iia, catt rrhal, at' lMuNsa't wolitanites, 179. diphtlheritic, 114. Mluscles of eyeball, description of, t, Eyin, 1 IS8, go ttnoerrho aldI 1.09, equtlibr itt of, 31, 8 -i etc. g ranulii, testing conldition of, 8, I herpeie, 12t). by prism1s, 85. etc. neonator'ni, 103. pi)horomreter, 87'. phtlyteltttel ar, 129. affections of, 8$1, 263. purulint, f11. paralysis of, 2)t puistular, 129. tMuscult astheuopia, 84. s.erofutlotsi, 125. treatment of, 8i. [ symlpatletic, 3I..1 tenotomn ii, 87, 91 tlarsi, 280. Mydriasi, 167. Ophtliamitisi, treatment of, 177. Myopia, W1. )Opht hal1toseope, t37 catse, 53, 54. appeaatnet of fitmdu with, 42, correction by glasses, 58. reutinal vessels with), 43. senl is, 93. bio t l t a, t 0. diagnosis of, 054. direct exa\niniation Awitli,'2, ophthatllnioseopic ai ppearance in, how to u se, 40. oh57, 7,t importance to generil pr aetition-'pro}gress oft 8, 2. erl, 4. treatment of, 7[ indirect exain. witi, 41. hygienic, 62. inverted iniare with 41, 412. preventitve, P62, etc, liebreich's, 3 8. surgical, 6. t the " refraction,'" 40. M3yosi,I 0. p rinciples of, 37. INDEX. 855 Ophtthahnoscopic exam, nceessar in l Photopthobia, remedie:s fo, 131, 380. tchromie headaches anfd in tall Sut. I Pysi >ol ica l excsaatito o4 f ot)ltie pee(ed disease of the brain 47, 21. I nerv, 180. Optic axes, contverg enc of, in ta cc - I t hyioloy of vtisiont, 19. modation, t50. Piniitecula, 13:. disc, how \to t rlt it, 1.1 Ptlstelr, ijuc from, 8300. Iiterve anatomn o tl It. reat e nt ott i,.0., atrophy oif, 2'. Posterior istapIli tln 5.0. tisiases tof, t, e. Powdet, injutries frfom explosionl of, ovdl aptpearai e of, 2, 82. I 07. neuritis, 213. I 1esb( opi i, 0)2. Optical defects' tl irer-eindiable, 2, treatientt of, 92 thie remedtiablf t I riss, ction oie, 4. 8isms, a n o f,,:, 88etc.i, Orbicultarit s para, pafl s of t, f testi ng strl gtilt of imutcles jpasi t of,.t 2 8', 89 88 t. Orbit; (iseas.'es of, 30ifi. ProlaiSe of itri, 13. diagltosis of, i2. Pterygiuitt 18. Oscillations of the evebal,'09., P'to as, tieattientll of, 287. Pu pil abnoiiaI dilationt of I170 dettsctripftion o f 14. P1A, d iaginostic value of, ), eonti action of, I 70. irmcdies, external, 54, 147, 148, atrtiieia dilation of, 171. 101, 1 2, 192, 1983, 21 -, contrai tioi of, 17;. remiedies, internal, 310, etc. closure of, 1041, 2.8. Pannus;, P.urulent ophthalmia, 01. Panop0htha4itis. t77. of itnf a ts, 1:t3. treatment of, t1. Pustulia oiph.lthali-a, I'Patac teCsis of cornea't, j4I), 143, 146. Piaralvis of ciliary imntticl, 28, levatot- palpeb l}l2ii 6. QUAt)tR TS of 0corlea, 8, nerlve, fourtfh, t 26f sixth, -4,'? third., 2;0 Ai: 1.r) Y increasing IpresOyopia 02, rectuls externst, i.i, Refraction, tanomatis o ft 5. inferior, 2 >:,. e1i fraction ill ambltyopiat, 222. titrnis, - 2f01. asti atfism i, 1t, 77 ttipl1ior,.85.1 hp 1rml ot ptl:ia, 04, $1, 15. superior oblique, 25, inopia, o5. Ptaralytic affecetios, ctauses of, 2 -4. normally fretactive tyes, 5., etc, treatlcilent or t0;71 differs ftrom accomml odationt, t0. surgical, of, 24t)'. e imedtic:. istttea, tr:l430: 3..l etectricity, 207. Retina, lpopltexy ot, 201i. fPasiamrmit's operation, 106. amneithesi rctmre, 2:31. iPertiotioa1o1n of cornea, 149f. anatony of, i,. lac. sa.c, 9. h lperta nii of, t 99. Perichoroidal space, 9. nerves ain vessels of, 10. Photophotbia i corneitis 3, 13- etc. pigment, layer of, 10, iritis, l5c. putrple of. 20. ctitnal asthentltopia, 230. caner 1of, 2i11. scroftltts ) ophthal., 131, etc, detachtnenlt of, 208. not a symptomo of retiitis, 310. diagnosis, 209. 356 INDEX. tRetina, emlbolism., central artery oft21l Speclact es, pantoseopie, 2538. klioain of, 21.1 pris tict, 258. I'hyper'ania of, t99t1, stetiopt ait, it3., lypei. lithesti: a otf, 2:0. Spigelia, use of,: 333 il farnt mait io' 20,1. Staptihylona aterior, 148. oi:htttlalinoseopic appearance of, Staphtyagria, u *of; C 33,. 20l, Stillingin, use of, 33. pitaralyx is of, I1S2.1 Stratbisimus, 26-. ttitlitis, 201. alternating or binocular, 270. albtttumn titm a, 203. catu'es of,'*7i 2 71 apoplt.l'ctie ca 21i0. coleolitant, 20. p)ar'eneltlymois, 201. e ntvergeit, 270. pigmlnittosa, 2)7. di vergentt, i72, sy p ti t icti, 2t,. dy rtinic, 81, di ttagitmi of, 201), etasui ienr t of,'27'. Retinotscoti, 70. o:perattiont for, t 26. lR ibeu imatic ii tis,.1. pa raly t tic, 2;5, etc. periodic or conitiriled, it70, 27,5. prilttry at.n secotllary dteviation SA8, tile lael rtal, It. i, 272. Stnitis: li operutilon, 14t 8 re n tdiu's for, 274. Sel tittml tclltalt of, 6. surgictal treatt entt t of, 276. Stceritis or ep:is:leritik, 1S2, 15. lhgieniC, 2t4. Selerot Iu atli\t:tt otf 6. Stricture's of lach, passiages, 289, etc antertior stitx) m. f, to 148. treattent oft 291, etc. posterior staplht tolin of, 5t. by probiti, 29). iwoutnd oft ti, stltves, 208. Selerotico-choroi ditis posterior, o5. Stilt ng mtlhotod, 299. ditagosis of, it). SItrmous ophlttt alia i 1$5. Selerotont, 197. coorneiti., 134, etc. Sercond ight, 2 it 1 is, i t6. Setlle etalat-ra. 20, Sutlpenso' tligiamn t of lens, 13. Short sigcil, t 1. Svmtbtephiaron, 309., Simulttion of blinteltse.;, 27. Sy7mpatt:p ti c irr itation, 319. Sixtit nerve, paralysis of, S26, oph ilthatia, l 3:.:. Sketch oif rise and progress of ophtltl- cIus, 316. mnic surgery, I. treatment, geeneral, 319. Snowl blind ntess, 231 by operat iot,:I7. Soft: eaitrate, 2:9. wthen to operate, 318. treatmentt t of, 2A Syn0tdeet'omy,.or peritomyt 123. Sparkling synlthcltis, t' 8. Syphilitie diseae of iris, 156. Spasm of ciitary mtstec, 218. corneatc, 138. orbie nlaris i uscle, 28. retina, 205. S'pectacleI, 257. cattaact, 257, c.ylindri.ct-lt i. TAx,SA, ttlmors, 281. rdtcentretd, 25. Itar-tr emetic, use otf, 333, kinds of, 257. ITatooing the cottia, b151 INIDX. 354'lcnollltU capsutile 17. Visio, state of, itf diagin)stic value, vlymphI spwe, 18. 31, 22l, 2821 Terl0otoi y in squint, St6.i wetakness of, See Asihewt)piit. in dynlvlamilic squint, 87. Vitreous, affeetions of, 313. Tesiul't of globe, to dIctcrmineu, 28. anatoimy of, 13. in glaucoma, 20t, 2083, choestrine i $r 180, operations for in trea, ed 0 93, 90s c e ystieri in, 180. I9H7. i utidlit of, 180.'Ts t tyvpe for astigmaatis, 80. foretin bodies in, t10. for readingt, 39. hemorrllamg into, 1-1. to determine1 distant visioin 341. inflamiationt of, 178,'Traumati ciatairact, 2 5 opalities of, 178. iritis, 313. Tremultouts iris, 171, 265. Trichiasis, 283. W, \ ts of conjunctivai, 133. Tumoir s ot choroidi, 11. eyelids, 285. conjulnctliva, 133. Weak sight. See As'Qihemt uit eyeidts, 28.$ Wouiii is of evebtall, 1t0. iris, 17 l eyetids *$3i retina, 2i iris, t 13'ilroi i 1, 5. sypat etitc inlttaunation from, tUiCmEs of cornea, 144. (ii eyelids,'283. ease of, 283. pi)er lid, how to reverse it, 26. Y hil o itsot, apitteantcte o, 4 t how to fid it. wvit the ophtllha (oscop:e, 41, Yi;ato, vorticosat, 7-0. Vision, aicuteness of, 30. ZtINC, use of, 333, double, 32^26-4 Z ine, phosph., use of, 333. field of, 31. Zonule of Zinn, 13.