B 477037 141 ARTES 1837 SCIENTIA VERITAS LIBRARY OF THE UNIVERSITY OF MICHIGAN FLURIBUS UND SI-QUAERIS PENINSULAM AMOENAMU, CIRCUMSPICE " V.U.O. V.R..0 V.LR V.U. V.I.E. V.E. V.I V.B. B PLATE I. V.C. A A A.R VID AIG P.P. P.V.. A.U.O. A.P L.R A.U. A.V ~A.V.H. ALE AE A.I. ALE SCHEMA OF THE GENITAL CIRCULATION (Auvard and Devy). A. A. Aorta. V. C. Inferior Vena Cava. A. R. Renal Artery. V. R. Renal Vein. A. U. o. Ovarian Artery. V. U. O. Ovarian Vein. A. 1. G. Left Common Iliac Artery. V.I. D. Right Common Iliac Vein. A. I. E. External Iliac Artery. A. I. Internal Iliac Artery. V. I. E. External Iliac Vein. V. I. Internal Iliac Vein. A. E. Epigastric Artery, giving off A. L. R., Artery of the Round Ligament (L. R.). V. E. Epigastric Vein, receiving v. L. R., Vein of the Round Ligament. A. P. Puerperal Artery. P. P. Pampiniform Plexus. A. U. Uterine Artery. v. U. Uterine Veins. A. V. Vaginal Arteries. P. V. Vaginal Plexus. A. V. H. Vulvo- Vaginal Branch of the Internal Pudic Artery. V. B. Veins emptying into the Internal Pudic Vein and also into the External Hemorrhoidal Veins. B. Bulb of the Vagina. V. Vulva. U. Uterus. T. Fallopian Tube. o. Ovary. v. A TEXT-BOOK OF GYNECOLOGY. 5286 == BY JAMES C. WOOD, A.M., M.D., PROFESSOR OF GYNECOLOGY IN THE CLEVELAND MEDICAL College; for eight YEARS PROFESSOR OF OBSTETRICS AND THE DISEASES OF WOMEN AND CHILDREN IN THE University of MICHIGAN, HOMEOPATHIC DEPARTMENT; FELLOW OF THE BRITISH GYNECOLOGICAL SOCIETY; FOUNDER MEMBER OF THE INTERNATIONAL PERIODIcal congress of GYNECOLOGY AND OBSTETRICS, AND AN HONORARY PRESIDENT OF THE BELGIUM SESSION OF 1892; EX-PRESIDENT OF THE HOMEOPATHIC MEDICAL SOCIETY OF THE STATE OF MICHIGAN; MEMBER OF THE AMERICAN INSTITUTE OF HOMEOPATHY; HONORARY MEMBER OF THE HOMEOPATHIC MEDICAL SOCIETY OF THE STATE OF NEW YORK, ETC. WITH TWO HUNdred and ten ILLUSTRATIONS. PHILADELPHIA: BOERICKE & TAFEL. 1894. COPYRIGHTED, 1893, BY BOERICKE & TAFEL. PRESS OF WM. F. FELL & CO., 1220-24 SANSOM ST., PHILADELPHIA. ΤΟ THE MEMORY OF My Father, Major Henry E. Wood, AND My Mother, THIS BOOK IS AFFECTIONATELY DEDICATED BY THE AUTHOR. • PREFACE. When, four years ago, the publishers of this volume, Messrs. Boericke and Tafel, requested me to write a text-book on gyne- cology, I consented to undertake the task only after receiving assurances from them that their views were in entire harmony with my own, regarding the field to be covered by such a work. An ideal text-book, according to my conception, was one which should not only embody in concise form for the specialist the most advanced teachings of the American and European schools of gynecology, but should present these teachings in such a way as to enable the student of medicine and the non-specialist to obtain at least an intelligent knowledge of the subject without exhaustive research. That I have fallen far short of this high ideal in the succeeding pages is apparent to no one more plainly than to myself: yet I have had it constantly in mind. An experi- ence of nine years as a teacher of gynecology has convinced me that minutiæ are essential to the successful teaching of this most important branch of medicine. I have, therefore, endeavored to lead the student on, step by step, into the broad field of the specialty, first dealing with those preliminaries without which he is ill-fitted to proceed further. I have devoted much space to diagnosis, especially to the diagnosis of abdominal tumors, believing most emphatically that blind gynecology has been the curse of womankind. I have introduced more than the usual number of illustrations and clinical cases, a feature which, I think, will aid the reader greatly in comprehending the text. Finally, I have endeavored so to present the treatment of the various affections dealt with that the busy practitioner may, without un- necessary loss of time, bring to his gynecological patients those agents and methods which have been devised and are now being employed by the leading specialists of both schools. V vi PREFACE. With the foregoing objects in mind I have largely eliminated historical data and profitless discussion of theories, at all times referring the reader for more extended information to special literature. I have also omitted the usual chapters devoted to diseases of the breast and diseases of the rectum, subjects which, although essentially gynecological, have come to be treated in various special works devoted to them. I cannot but feel that the profession will, appreciate the large number of illustrations from the Museum of the Royal College of Surgeons, London. I am not aware that any American specialist has before utilized that splendid pathological collection for this purpose. All of the photographs of these specimens, as well as photographs and drawings obtained from my own cases, were taken under my personal supervision. In the several series of illustrative cases, it has been my aim to introduce only those which serve to illustrate or emphasize the points dealt with in the text. Whenever such points are better illustrated by unsuccessful cases I have not hesitated to record my failures. In conclusion, I desire to acknowledge my indebtedness to the publishers of "The Annual of Universal Medical Sciences," in providing me with references and advanced proof-sheets of that most excellent publication; to Mr. Frederic S. Eve, curator of the Museum of the Royal College of Surgeons, for his kindness in granting me unusual privileges in photographing specimens; to Messrs. Geo. Tiemann & Co., for having pre- pared for me new electrotypes of the instruments illustrated; and to my assistants, Drs. Mary Denison, Ida C. Woolsey, Evelyn S. Pettit, and C. M. Thurston, for having rendered me invaluable service in the way of research, proof-reading, trans- lating, etc. CLEVELAND, January 15, 1894. JAMES C. WOOD. CONTENTS. CHAPTER I. THE CAUSES OF GYNECOLOGICAL DISEASES. Inherited Feebleness of Constitution.-Defects in or Absence of Develop- ment.-Acquired Feebleness of Constitution.-Deficient Air and Ex- ercise.-Improper Dress.-Exposure During Menstruation.-Improper Care During and After Parturition.-Reflex Functional Disturbance and Nervous Disorders.-Development of New Growths and Malignant Disease. Inflammatory.-Accidental CHAPTER II. THE ANATOMY OF THE FEMALE PELVIC ORGANS. Embryology.-Development of Ovum, Showing Successive Changes Fol- lowing Fecundation.-External Genitals. Muscles of the Female Perineum. The Vulvo-Vaginal Glands.-The Fascia of the Pelvic Floor.-Deeper Fascia.-The Perineal Septum or Triangular Liga- ment.-The Pelvic Floor Dissected from Above-Fascial Coverings of the Muscles of the Pelvic Floor.-The Relations of the Pelvic Organs with the Pelvis and with One Another.-Peritoneum.—Round Ligaments.-Pelvic Pouches.-Cellular or Connective Tissue of Pelvis. The Uterus and Annexa.-The Vagina.-Blood-Vessels, Lymphatics, and Nerves. PAGES 17-29 30-57 CHAPTER III. CASE TAKING. Case Record. The Significance of Pain in Diagnosis:-As Regards Loca- tion-As Regards Function-As Regards Posture. CHAPTER IV. THE SIGNIFICANCE OF DISCHARGES IN DIAGNOSIS. Physiology. Pathology : G Mucous Purulent-Watery - Sanious-Of- fensive-Hemorrhagic.-Diagnosis of Bodies Expelled from the Va- gina.-The Microscope as a Means of Diagnosis. CHAPTER V. PHYSICAL EXAMINATION. Instruments and Appliances Necessary for Diagnosis.-Positions for Exami- nation • CHAPTER VI. PHYSICAL EXAMINATION.-(Continued.) Immediate Touch.-Vaginal Touch.-Rectal Touch.-Vesical Touch.- Double Touch.-Conjoined Manipulation 58-69- 70-76. 77-92 93-104 vii viii CONTENTS. CHAPTER VII. PHYSICAL EXAMINATION.-(Continued.) Intermediate Touch:-Uterine Sound-Vesical Sound.-Immediate Sight: -External Inspection-Per Speculum.-Produced Sounds :-Percus- sion.-Existing Sounds :-Auscultation.-Conclusions CHAPTER VIII. THE GENERAL PATHOLOGY OF GYNECOLOGICAL DISEASES. Preliminary Considerations.-Nervous and Blood Supply of the Pelvic Organs. How Distant Organs are Involved.-Nature of the Local Lesion Causing Reflex Symptoms.-Forms of Hyperemia.-The Se- quelæ of Hyperemia.-The Neuroses.-How General Symptoms are Induced by Local Disease.-How Local Disease is Induced by General Symptoms.-Temperament and Constitutional Bias. CHAPTER IX. GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. PAGES 105-116 117-123 General Considerations.-Indigestion.-Constipation.-Nervous Prostration. 124-137 CHAPTER X. LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. General Considerations.-The Vaginal Douche.-Local Applications.— Astringents and Styptics.-Narcotics.-Disinfectants.-Caustics.-The Vaginal Tampon. CHAPTER XI. ELECTRICITY IN GYNECOLOGY. General Considerations.-Galvanism.-Faradism.-The Franklinic Current. -Apparatus: -- Galvanometer-Water Rheostat - Electrodes - The Application of the Franklinic Current.-In Amenorrhea.-In Dysmen- orrhea.-In Subinvolution.-In Superinvolution and Atrophy.—In Ovaralgia.-In Chronic Ovaritis.-In Chronic Pelvic Inflammation.- In Uterine Displacements.-In Endometritis.-Schema CHAPTER XII. ANTISEPSIS IN GYNECOLOGY. 138-151 152-169 General Considerations.-The Agents Employed.-The Operator and As- sistants. The Patient.-The Operating Room.-The Operation.-The After-treatment.-Antisepsis in Ordinary Gynecological Examinations. 170-183 CHAPTER XIII. THE HYSTERO-NEUROSES; HYSTERIA. Definition.-General Considerations.-Forms of Hystero-Neuroses.—The Physiological Hystero-Neuroses.-Diagnosis.-Prognosis. CHAPTER XIV. THE HYSTERO-NEUROSES; HYSTERIA.-(Continued.) Symptomatology.-Disorders of Sensibility.-Alterations of Motility.— Circulatory Disturbances.-Anomalies of Secretion and Excretion.— Disorders of Respiration. • 184-191 · 192-208 CONTENTS. ix CHAPTER XV. THE HYSTERO-NEUROSES; HYSTERIA.-(Continued.) Disorders of the Gastro-Intestinal Canal.-Disorders of the Skin.-Gland- ular Disturbances.-Disorders of the Nervous System.-Epilepsy as a Hystero-Neurosis.-The Hysterical Paroxysm. CHAPTER XVI. MENSTRUATION AND ITS DISORDERS. PAGES 209-225 Physiology of Menstruation.-General Considerations.-Definition.—Theo- ries.-Source of Hemorrhages.-Changes in Endometrium.-Amenor- rhea :-Primary-Secondary-Retention of the Flow-Treatment.. 226-237 CHAPTER XVII. UTERINE HEMORRHAGE. General Considerations.- Causes.-Conclusions.-Treatment :— General- Conduct of Patient During the Period-Treatment of Local Causes- Immediate Control of Hemorrhage―Therapeutics CHAPTER XVIII. DYSMENORRHEA. • 238-256 Schema Of.-General Considerations.-Neuralgic.-Ovarian.-Congestive and Inflammatory.—Obstructive.-Membranous.-Treatment . CHAPTER XIX. MENOPAUSE. • . 257-279 Definition.—Anatomical Changes.- Symptoms.-Treatment.— Illustrative Cases. 280-289 CHAPTER XX. VICARIOUS MENSTRUATION. Definition and Synonyms.-Schema Of.-Theories.-Treatment. CHAPTER XXI. STERILITY AND IMPOTENCE. 290-305 Causes.-Treatment.-Dyspareunia. . CHAPTER XXII. DISEASES OF THE EXTEernal OrgaNS OF GENERATION. General Considerations.-Deformities of the Vulva.-Eruptions.—Vulvitis. -Phlegmonous Inflammation of the Labia Majora.—Inflammation and Abscess of the Vulvo-Vaginal Glands.-Pudendal Hemorrhage.- Pudendal Hematocele.-Pudendal Hernia.-Hydrocele.-Edema of the Labia Majora and Nymphæ.-Neoplasms of the Vulva. CHAPTER XXIII. 306-319 • 320-341 DISEASES OF THE EXTERNAL Organs of GeneraTION.—(Continued.) Pruritus Vulvæ; Hyperesthesia of the Vulva. 342-351 X CONTENTS. PAGES • 352-362 CHAPTER XXIV. VAGINISMUS; COCCYGODYNIA CHAPTER XXV. CONGENITAL AND ACQUIRED MalformATIONS AND DISEASES OF THE VAGINA. Atresia Vulvæ.- Imperforate Hymen.- Persistent Hymen.-Congenital Atresia Vaginæ.-Acquired Atresia Vaginæ.-Double Vagina.—Double Hymen.-Vaginal Cysts.-Hermaphrodism CHAPTER XXVI. Anatomy.-Varieties.-Treatment VAGINITIS. 363-377 • 378-387 CHAPTER XXVII. SENILE OR ADHESIVE Vaginitis. General Considerations and History.-Diagnosis and Prognosis.-Etiology and Pathology.-Treatment. CHAPTER XXVIII. ACUTE INFLAMMATORY DISEASES OF THE PELVIC ORGANS AND Tissues. Acute Metritis and Endometritis. -Acute Pelvic Cellulitis and Peritonitis. Acute Ovaritis and Salpingitis. • CHAPTER XXIX. CHRONIC METRITIS AND ENDOMETRITIS. Chronic Cervical Endometritis and Granular and Cystic Degeneration of the Cervix.- Chronic Corporeal Endometritis and Uterine Fungosities. -Chronic Metritis (Subinvolution, Hypertrophy, and Areolar Hyper- plasia of the Uterus). CHAPTER XXX. PELVIC HEMATOCELE. Intra-Peritoneal.-Extra-Peritoneal 388-397 398-428 429-462 463-479 CHAPTER XXXI. PELVIC ABSCESS. General Considerations.-Symptoms.-Differentiation.-Prognosis.—Treat- ment • 480-49 CHAPTER XXXII. DISEASES of the Urethra and Bladder. Acute Urethritis.-Acute Cystitis.-Chronic Urethritis and Cystitis. 492-505 CONTENTS. xi CHAPTER XXXIII. DISEASES OF THE URETHRA AND BLADDER.-(Continued.) Malformations of the Urethra.-Stricture of the Urethra.-Prolapse of the Mucous and Submucous Tissues of the Urethra.-Dilatation of the Urethra. Fissure of the Urethra.-Vascular Neoplasms of the Urethra. -Urethral Caruncles.-Polypi of the Urethra.-Irritable Urethra.-Ves- icai Calculi.-Neoplasms of the Bladder.-Vesical Parasites.-Hema- tura.-Irritability of the Bladder.-Retention of Urine. CHAPTER XXXIV. FISTULÆ OF THE FEMALE GENITAL Organs. Vesico-Vaginal. Urethro-Vaginal. Uretero-Vaginal.- Vesico-Uterine.— Uretero-Uterine PAGES 506-517 518-536 CHAPTER XXXV. FECAL FISTULÆ. Recto-Vaginal.—Recta-Labial.—Entero-Vaginal.--Entero-Vesical. . . . 537–542 CHAPTER XXXVI. DISPLACEMENTS OF THE Uterus. General Considerations.-Etiology.-Symptoms.-Anteversion.-Anteflex- ion.-Retroversion.-Retroflexion CHAPTER XXXVII. 543-567 DISPLACEMENTS OF THE UTERUS.~(Continued.) Lateral Displacements.-Prolapse of the Uterus.-Inversion of the Uterus. 568-582 CHAPTER XXXVIII. FIBROID TUMORS OF THE UTERUS. Definition.-Varieties.-Pathology.-Degenerative Changes.-Etiology.- Symptoms. Physical Signs.-Progress and Termination.-Prognosis. 583-598 CHAPTER XXXIX. FIBROID TUMORS OF THE UTERUS.-(Continued.) Palliative Treatment.-Surgical Treatment.-Oöphorectomy For.-Abdom- inal Section For.-Fibroids During Pregnancy.-Fibro-Cystic Tumors of the Uterus CHAPTER XL. 599-614 615-626 POLYPI OF THE UTERUS: THERAPEUTICS OF UTERINE FIBROMATA AND POLYPI CHAPTER XLI. MALIGNANT DISEASES OF THE UTERUS. Carcinoma of the Cervix.-Carcinoma of the Body of the Uterus.-Sar- coma Uteri. 627-640 xii CONTENTS. CHAPTER XLII. MALIGNANT DISEASES OF THE UTERUS.-(Continued.) PAGES Treatment of Carcinoma and Sarcoma of the Uterus:-Palliative-Surgical. 641-662 CHAPTER XLIII. CYSTIC AND ALLIED Diseases of THE UTERINE APPENDAGES. Ovarian Tumors.-Simple Cysts.-Multiple Cysts.-Proliferous Cysts.- Dermoid or Cutaneous Proliferous Cysts.-Papillomatous Cysts.-Cysts of the Broad Ligament.-Papillomatous Cysts.-Parovarian Cysts.- Enlargement of the Hydatid of Morgagni.-Solid Tumors of the Ovary :-Fibroma-Carcinoma-Sarcoma.-The Pedicle of Ovarian Tumors. 663-672 CHAPTER XLIV. CYSTIC AND ALLIED DISEASES OF THE UTERINE APPENDAges. -(Continued.) Symptoms.-Course and Termination of Ovarian Tumors CHAPTER XLV. 673-682 CYSTIC AND Allied DISEASES OF THE UTERINE APPENDAGES. —(Continued.) Diagnosis of Ovarian Tumors.-Differentiation.—Method of Tapping Ovarian Cysts . 683-701 CHAPTER XLVI. OVARIOTOMY. The General Principles of Abdominal Section.—When Ovariotomy Should be Performed. Operating Table.-Clothing-Preliminary Details.- Temperature of the Room.-Arrangement of Instruments.-Abdominal Incision. Intra-Abdominal Manipulations.-Tapping the Cyst.-Man- agement of Adhesions.-Treatment of Pedicle.-Drainage.-Closing the Abdominal Wound.-Dressing the Wound.-Incomplete Ovariot- omy.-Encapsulated Ovarian Cysts. CHAPTER XLVII. Ovariotomy.—(Continued.) After-treatment.—The Pulse and Temperature.-Tympanites.-Septicemia and Peritonitis.-Therapeutics.-Illustrative Cases. CHAPTER XLVIII. INFLAMMATORY DISEASES OF THE UTERINE APPENDAGES. 702-723 • 724-736 Acute Salpingitis and Ovaritis.—Non-Cystic Oöphoro-salpingitis.— Cystic Oöphoro-salpingitis.- Pathology.-Progress and Termination.- Prog- nosis. CHAPTER XLIX. INFLAMMATORY DISEASES OF THE UTERINE APPENDAGES.— (Continued.) Treatment of Non-Cystic and Cystic Oöphoro-salpingitis: -Palliative-Sur- gical. Illustrative Cases. • 737-753 754-762 CONTENTS. xiii Diseases of the UTERINE APPENDAGES.—(Continued.) Congestion of the Ovary.-Prolapse of the Ovary.—Ovarian Neuralgia (Ovaralgia) CHAPTER L. ECTOPIC PREGNANCY. PAGES • 763-768 — Definition.- Varieties. Etiology.- Pathology.—Symptoms. Differential Diagnosis. Prognosis.—Treatment.-Use of Electricity In.-Laparot- omy For.-Elytrotomy or Vaginal Extraction.-Illustrative Cases. 769-800 CHAPTER LI. LACERATIONS OF THE CERVIX UTERI. • History and General Considerations.—Frequency.—Etiology.-Varieties.— Pathology.-Symptoms.- Differential Diagnosis.- Prognosis.—Treat- ment.-Indications for Trachelorrhaphy.-Operation . CHAPTER LII. LACERATIONS AND INJURIES OF THE PERINEUM AND PELVIC FLOOR. General Considerations and Anatomy.-Forms of Injury.-Causes.-Spon- taneous Reparation.— Results. Treatment: Palliative-Primary Operation - Secondary Operation — Flap-Splitting Operation — Em- met's Operation-Hegar's Operation-The Author's Operation— Stoltz's Operation for Cystocele.-After-treatment of Colpoperineor- rhaphy. 801-814 815-846 ILLUSTRATIVE CASES. PAGE Profound Neurasthenia with Hystero-Epileptic Convulsions. The Weir Mitchell Treatment, 130 Neurosis of the Anterior Tibial Region Simulating Periostitis, Cured by Emmet's Operation, . 196 by Directing Treatment to Pelvis, 196 • 197 200 Hysterical Joint of Three Years' Duration, Simulating Morbus Coxarius, Cured Distressing Hyperesthesia of Sight and Hearing, . Reflex Paraplegia, Due to Anteversion and Urethral Fissure,. Cardiac Neurosis, Resulting in Organic Disease, Associated with, and Probably caused by, Laceration of the Cervix. Greatly Relieved by Emmet's Opera- tion, Cardiac Neurosis, Simulating Exophthalmic Goiter, Caused by Retroversion and Endometritis, . • 203 203 Cardiac Pain, Simulating Angina Pectoris, due to Pelvic Lesions, Circumscribed Erythema of the Lower Limbs, Cured by Correcting a Retrodis- placement,. 204 • • 204 Menorrhagia with Marked Vaso-Motor Disturbances, Cured by Dilating the Cervix and Curetting, 204 Hysterical Cough with Anteflexion and Dysmenorrhea, 206 · Reflex Aphonia, Cured by Removal of the Appendages, . Membranous Enteritis During Climaxis, . Reflex Asthma, Temporarily Cured by Removal of the Appendages, . Reflex Asthma of Eighteen Years' Standing, Cured by Removing Prolapsed Tissue from the Urethra, Acute Vomiting of Two Years, due to Anteflexion, Reflex Intestinal Neurosis, Eczema of the Face, Cured by Perineorrhaphy and Trachelorrhaphy, 206 • 207 208 211 • 2II 211 213 Acne Pustule on the Side of the Nose, Recurring with Each Menstrual Period,. 214 Hystero-neurosis of the Liver, Simulating "Gall-Stones," 215 Suicidal Melancholia with Retroflexion,. 216 Epilepsy Mitior (petit mal), Cured by Operating upon the Cervix and Perineum, 219 Epilepsy of Six Years' Standing, Greatly Relieved by Removal of the Append- ages, 220 t xiv ILLUSTRATIVE CASES. XV PAGE Epilepsy of Fourteen Years' Duration, Greatly Relieved by Removal of the Ap- pendages, 221 Epilepsy Greatly Relieved by Divulsing the Cervix and Rectum, Xanthoxylum in Amenorrhea, . 222 237 Hydrastis Canadensis in Uterine Hemorrhage, 254 Cannabis Indica in Menorrhagia,. 254 Obstinate Menorrhagia, Cured by One Application of the Curette, · 255 Uterine Hemorrhage, Due to Interstitial Fibroid, Controlled by Curetting, 256 Borax in Membranous Dysmenorrhea, . 275 Platina in Dysmenorrhea, . 275 Viburnum Opulus in Dysmenorrhea, . 276 Cocculus in Dysmenorrhea, Guaiacum in Chronic Ovaritis with Dysmenorrhea, . • Xanthoxylum in Membranous Dysmenorrhea, Milfoil in Membranous Dysmenorrhea, . Guaiacum in Spinal Irritation with Ovaritis and Dysmenorrhea, . Cases Showing the Beneficial Effects of Divulsion in Obstructive Dysmenorrhea, 278 Reflex Nervous Symptoms During the Menopause, Cured by Divulsion and the Application of Carbolic Acid, . Dipsomania During Menopause,. Kleptomania During Menopause, • Nervous Aphonia During Menopause, • The Menopause Delayed by Fungosities of the Endometrium, 276 277 277 277 278 · 287 288 288 288 289 Diarrhea and Morbid Perspirations During Menopause, 289 Dropsy and Hematuria Attending Pregnancy, 301 Vicarious Hemorrhages from the Stomach, Eyes, and Nose, • 301 Vicarious Hemorrhages from Strumous Scars, Eyes, Knees, Thighs, etc., Vicarious Hemorrhage from the Leg, 301 • 302 Vicarious Leucorrhea, 302 Vicarious Hemorrhage from Lower Lip, 302 Amenorrhea with Vicarious Hemorrhage, 303 Vicarious Hemorrhage from Varicose Ulcers of Leg, 303 Singular Case of Vicarious Hemorrhage, 304 Vicarious Hemorrhage from Hemorrhoidal Tumors of the Rectum, Vicarious Hemorrhage from a Mole on Forehead, 304 304 • Vicarious Epistaxis, Double Hymen, • Gonorrheal Vaginitis Giving Rise to Acute Pelvic Inflammation, Senile or Adhesive Vaginitis Associated with Obstin¹te Dyspepsia, Senile or Adhesive Vaginitis, Senile or Adhesive, Associated with Insanity, 305 • 374 383 • 395 396 Eversion of the Cervical Mucous Membrane in a Virgin, Simulating Cervical Laceration, 396 • 435 Corporeal and Cervical Endometritis, Cured by Galvanism, 457 Areolar Hyperplasia, Cured by Galvanism, . 457 xvi ILLUSTRATIVE CASES. Cervical Endometritis, Cured by Galvanism, PAGE Pelvic Abscess and Fecal Fistula Following Laparotomy, Cured by Abdominal Section, Chronic Metritis of Two Years' Duration. Complete Relief After Three Applications of Galvanism, . Chronic Purulent Endometritis of Five Years' Duration. Complete Relief After Eight Negative Cauterizations, Chronic Metritis of Five Years' Duration. Uterus Reduced to Normal Size and Disappearance of Symptoms After Five Applications of Galvanism to the Cavity, . 458 • 458 458 459 Operation for the Creation of a new Urethra, Abscess of the Left Ovary and Broad Ligament Following Puerperal Cellulitis and Peritonitis. Laparotomy. Recovery, . . Pelvic Abscess Following Hematocele. Laparotomy. Recovery,. Prolapse of the Mucous and Sub-mucous Tissues of the Urethra, Removal of a Vesical Calculus through Vagina, · Retroflexion Giving Rise to Obstruction of the Right Ureter,. Retroversion of the Uterus with Procidenția of the Second Degree. rhaphy and Gastro-hysterorrhaphy. Recovery, Obstinate Retroflexion of the Uterus with Cystic Degeneration and Prolapse of the Right Ovary. Gastro-hysterorrhaphy and Salpingo-oöphorectomy. Recovery, • Intractable Dysmenorrhea Following Ovariotomy for the Removal of a large Ovarian Cyst. Oöphorectomy and Gastro-hysterorrhaphy. Recovery, Large Myomatous Tumor Springing from Cervix, . 566 489 490 491 • 507 • • 514 534 555 Perineor- • 566 • 566 572 Removal of a Large Fibroid together with a Pregnant Uterus. Death, Large Fibrous Polypus Springing from Cervix, Diffuse Sarcoma of the Uterine Mucous Membrane. Vaginal Hysterectomy. Recovery, 611 617 • 657 Carcinoma of the Body of the Uterus. Vaginal Hysterectomy. Recovery, . Epithelioma of the Cervix. Vaginal Hysterectomy. Death, Cancer of the Uterus and Annexa. Exploratory Laparotomy. Death, Ovariotomy for Ruptured Cyst. Recovery, 661 662 676 732 Large Multilocular Ovarian Cyst with Hemorrhage into its Interior. Great Rapidity of the Pulse Following Operation without Corresponding Rise in the Temperature. Recovery, Intra-ligamentary Cyst Dissecting the Peritoneum in Front as Far as the Liver. Complete Enucleation of Cyst. Death,. 733 733 Large Proliferous Cyst Weighing Forty Pounds. Ovariotomy. Recovery, Large Fibro-cystic Tumor of the Ovary, with Long Pedicle, Giving Rise to Enormous Distention of the Abdomen from Ascitic Accumulation. Opera- tion. Recovery, • 734 734 Parovarian Cyst Weighing Twenty Pounds. Operation. Recovery, . Exploratory Incision for Papillomatous Degeneration of Ovaries. Hemorrhage which was Controlled by Extensive Gauze Packing, 735 Profuse 736 ILLUSTRATIVE CASES. xvii Rupture of Tubo-ovarian Cyst While Practising the Bimanual, . Pyosalpinx, the Result of Gonorrheal Infection. Oöphoro-salpingotomy Followed by Intestinal Obstruction. Reopening of the Abdomen at the end of Forty- eight Hours. Recovery, Pyosalpinx of Right Side with Cystic Degeneration of Ovaries and Retroflexion of the Uterus. Salpingo-oophorectomy and Gastro-hysterorrhaphy. Re- covery, . Hydrosalpinx of Right Side with Cystic Degeneration of Corresponding Ovary. Interstitial Salpingitis of Left Side with Cirrhotic Degeneration of Left Ovary. Salpingo-oophorectomy. Recovery, . Oöphoritis of Twenty Years' Standing. Complete Prostration from Neurasthenia. Salpingo-Oophorectomy. Recovery, · Non-encysted Intra-peritoneal Pregnancy. Operation. Recovery, Interstitial Pregnancy Rupturing into Uterus. Recovery, Extra-uterine Pregnancy. Rupture. Death,. PAGE 747 758 759 760 • € 761 • 794 • 798 • 799 • ii PLATE LIST OF ILLUSTRATIONS. PLATES. PAGE 7. Dissection of Pelvis from Above (Savage), I. Schema of the Genital Circulation (Frontispiece). II. Topographical Relations of the Pelvic Peritoneum and Cellular Tissue, FIG. Showing Seats of Exudation in Inflammation, I. External Genitals (Martin), 2. Dissection of Perineal Region (Savage), • 3. Superficial Perineal Fascia, Anterior View (Savage), 4. Deeper Fascia of the Female Perineum; Triangular Ligament or Perineal Septum (Savage), • 5. Posterior View of Perineal Septum (Savage), 6. Perpendicular Transverse Section of Pelvis (Savage), 8. Perpendicular Section of Pelvis from Below Upward (Savage), 410 32 34 35 37 38 39 40 42 9. The Relations of the Muscular Floor of the Pelvis to the Presentation at the Last Stage of Labor, 42 10. Median Perpendicular Section of Pelvis (Cazeaux), 44 II. The Pelvic Organs and the Pelvic Cavities from Above (Auvard), 12. Frozen Section, Showing Peritoneum (Furst), 45 46 13. Pubic Termination of Round Ligaments (Savage), • 48 14. The Pouches and Reflections of the Pelvic Peritoneum (Hodge), 15. Uterus and Annexa, 49 51 16. Coronal Section of the Uterus Through Fallopian Tubes (Savage), 17. Tube, Ovary, and Parovarium (Henle), 18. Vagina in Vertical Section (Hart), . · 19. Relations of the Ureters at the Level of the Os Internum, as seen from Above (Polk),.. 20. Vesicular or Hydatidiform Mole (Museum R. C. S.), 52 53 • 55 56 75 21. The Harvard Chair, 22. Thomas's-Cusco's Speculum, 78 78 27. Wood's Speculum, 23. Nott's Virgin Speculum, 24. Brewer's Speculum, 25. Brewer's Speculum Used as a Sims's, 26. Goodell's Speculum, . 28. Sims's Speculum, 29. Mundé's Modification of Sims's Speculum, 30. Emmet's Self-retaining Sims's Speculum, 79 79 79 888 80 80 81 81 82 • xviii LIST OF ILLUSTRATIONS. xix FIG. • 31. Cleveland's Speculum, . 32. Simon's Specula, 33. Ferguson's Speculum, 34. Bi-valve Rectal Speculum, 35. Williams's Rectal Speculum, 36. Skene's Urethral Speculum, 37. Skene's Urethral Endoscope, 38. Cystoscope of Nitze and Leiter, 39. Simpson's Uterine Sound, 40. Sims's Flexible Probe, • 41. Long Angular Tenaculum, 42. Nott's Depressor, • 43. Hank's Hard Rubber Uterine Dilators 44. Wylie's Uterine Dilator, PAGE 82 82 83 83 84 84 84 85 85 85 86 86 86 86 45. Simon's Spoon Curette, 87 47. Bozeman's Dressing Forceps, • 46. Thomas's Dull Wire Curette, 48. Junker's Inhaler, 49. Latero-abdominal, or Sims's Posture (Skene), 50. Regions of Abdomen (Edis), 51. Conjoined Manipulation,. 52. Method of Introducing the Uterine Sound (Hart and Barbour), 53. Incorrect Method of turning Uterine Sound (Hart and Barbour), 54. Correct Method of Turning Uterine Sound (Hart and Barbour), 55. Digital Eversion of Rectum (Mundé), 56. Vaginal Irrigator, . • 57. Tamponnement of the Peritoneum (Pozzi). 58. Bozeman's Reflux Uterine Catheter, 59. Emmet's Curette Forceps, • 60. Cleveland's Glass Cervical Plug, . 87 88 88 90 95 102 107 108 • • 108 III 140 179 249 251 270 61. Hypertrophy of the Clitoris (Museum R. C. S.), 322 62. Hypertrophy of External Organs of Generation (Museum R. C. S.), 323 63. Epithelioma of the External Genitalia (Wood),. 340 64. Sims's Vaginal Dilator, 356 65. Imperforate Hymen with Distention of Vagina and Uterus, 368 66. Section of Vagina Showing Cicatricial Bands (Wood), 388 67. Senile or Adhesive Vaginitis (Wood), · 390 68. Senile or Adhesive Vaginitis (Wood), 69. Cross Section of Pelvis (Luschka), 70. Laceration with Erosion of the Cervix (Martin), 71. Erosion with Enlargement of Follicles (Martin), . 72. Fissured Cervix with Granular Mucous Membrane (Schroeder), 73. Ectropion of the Cervix (Auvard and Devy), 74. Cystic and Papillar Hyperplasia of Cervix (Mundė), . 75. Conoid Cervix, Pinhole Os (Palmer), . 76. Dilated Cervical Canal (Mundé), 77. Intra-peritoneal Hematocele, 392 406 430 430 • 431 432 432 • 453 453 • 466 XX LIST OF ILLUSTRATIONS. FIG. 78. Extra-peritoneal Hematocele (Auvard and Devy), . 79. Extra-peritoneal Hematocele (Auvard and Devy), 80. Reflux Catheter (Skene), PAGE 472 473 500 81. Prolapse of the Mucous and Submucous Tissues of the Urethra (Wood),. 508 82. Self-retaining Catheter (Skene-Goodman), . 83. Sims's Curved Scissors, 84. Bozeman's Straight Scalpel, . · 85. Method of Paring Edges of Urinary Fistula with Knife (Savage), 86. Method of Paring with Scissors (Savage), 87. Emmet's Needles, 88. Sims's Needle Forceps, 89. Introduction of Sutures, 90. Emmet's Counter Pressure Hook, 91. Sutures Passed, 92. Twisting the Sutures, 93. Sims's Shield,. . 94. Wood's Sponge Holder, 95. Wood's Wire Twister, 96. Removal of Sutures, • 97. Simon's Position for Vesico-Vaginal Fistula (Simon), 522 524 524 • 525 525 526 • 526 526 526 · 527 • • 527 528 528 98. Sutures Tied (Simon),. . 99. Operation for Vesico-Vaginal Fistula by Flap-splitting (Walcher), 100. Operation for Vesico-Vaginal Fistula by Flap-splitting (Walcher), IOI. Variations of the Positions of the Uterus caused by the Various Degrees of Bladder Distention, 102. Anteversion of the Uterus, 103. Anteflexion of the Uterus (Museum R. C. S.), 104. Graily Hewitt's Anteversion Pessary, 105. Thomas's Anteversion Pessary, 106. Thomas's Open-Cup Anteversion Pessary, 107. Retroversion of the Uterus (Museum R. C. S.), 108. Hodge's Closed Lever Pessary, • • 109. Thomas's Retroflexion Pessary, 110. Albert Smith's Retroflexion Pessary, III. Thomas's Cutter's Retroversion Pessary, 112. Thomas's Cutter's Anteversion Pessary, . 113. Gastro-Hysterorrhaphy (Leopold), 114. Utero-Vaginal Prolapse, • • 528 529 · 530 530 531 532 544 • 548 549 552 552 • 553 557 558 558 • 559 561 561 564 568 115. Complete Prolapse of the Bladder, Uterus, and Rectum (Museum R. C. S.), 569 116. Complete Procidentia of the Uterus, Vagina, and Bladder (Wood),. 570 117. Hypertrophic Elongation of the Cervix with Prolapse (Museum R. C .S.), 573 118. Inflated Soft Rubber Pessary, • 120. Thomas's Cutter's Cup Pessary for Prolapse, 119. Inflated Ball Pessary, 121. Inversion of the Uterus (Auvard and Devy), 123. Inversion of the Third Degree (Auvard and Devy), . 122. An Unimpregnated Inverted Uterus (Museum R. C. S.), . 574 574 574 576 577 578 LIST OF ILLUSTRATIONS. xxi FIG. PAGE 124. White's Uterine Repositor, • 581 125. Diagram, Showing the Beginning of Fibroma Uteri and Their Mode of Growth (Auvard and Devy), 584 126. A Uterus in the Walls of which are Eight or Nine Fibroid Tumors (Museum R. C. S.), 127. A Pregnant Uterus and Large Fibroid Tumor (Museum R. C. S.), 128. A Uterus with Two Large Fibroid Tumors (Museum R. C. S.), 129. Uterus and Annexa with Small Fibroid Tumor (Museum R. C. S.), 130. Fibroid Springing from Posterior Wall of Cervix, . 131. Greenhalgh's Tumor Forceps, • 132. Tait's Corkscrew for Hysterectomy, 585 586 588 589 • 591 601 604 133. Extra-peritoneal Method of Treating Pedicle (Hegar), 606 134. A Pregnant Uterus Together with a Subserous Fibroid (Wood), 612 135. A Uterus Containing a Fibrous Tumor in the Process of Pediculation (Museum R. C. S.), 616 138. Vascular Mucous Polypus Growing from Inner Wall of Uterus (Museum R. C. S.), 136. Submucous Fibrous Polypus Projecting into Vagina (Auvard and Devy), 617 137. Fibrous Polypus Springing from Cervix (Wood), . 617 618 139. Mucous Polypi (Schroeder), 619 140. Enlarged Pediculated Cystic Follicles (Beigel), 619 141. Aveling's Polytome, 623 142. Epithelioma of the Cervix (Museum R. C. S.), 630 143. Medullary Cancer of Cervix Invading the Vagina (Museum R. C. S.), . • 635 144. Cancer of the Cervix and Vagina (Museum R. C. S.), 636 145. Simon's Retractor, 648 D 146. Lee's Modification of Greig Smith's Broad Ligament Clamp, 649 147. Wood's Needle for Vaginal Hysterectomy, 650 148. Cancer of Uterine Body with Cystic Degeneration of Right Ovary (Wood), 661 149. Diagram of the Structures in and Adjacent to the Broad Ligament (Doran),. 664 150. Multilocular Ovarian Cyst (Doran), 664 151. Dermoid Cyst (Museum R. C. S.), . 667 152. Papillomatous Disease of the Broad Ligaments (Museum R. C. S.), 669 • • 153. Parovarian Cyst (Museum R. C. S.), 154. Parovarian Cyst (Museum R. C. S.), 155. Cancer of Uterus and Annexa (Wood), 156. Area of Dulness in Ovarian Cyst, 157. Area of Dulness in Ascites, 158. Position of Tables, Operator, Assistants, etc., During Ovariotomy (Doran), 707 159. Catch Forceps, 160. Elbowed Scissors, 161. Director for Dividing Peritoneum, 162. Emmet's Ovariotomy Trocar, • 163. Spencer Wells' Ovariotomy Trocar, 164. Wilcox's Cyst Forceps, 165. Spencer Wells' Cyst Forceps, 708 708 709 • 710 710 711 711 670 670 677 • • 688 688 xxii LIST OF ILLUSTRATIONS. FIG. 166. Spencer Wells' T-Forceps, 167. Keith's Ovariotomy Clamp, . 168. Cleveland's Ligature Forceps, 169. Staffordshire Knot, 170. Thomas's Curved Non-perforated Drainage Tube, 171. Thomas's Curved Perforated Drainage Tube, 172. Incomplete Ovariotomy, 173. Lymphatics of Uterus (Poirer), . 174. Hydrosalpinx (Museum R. C. S.), . 175. Tubo-ovarian Cyst (Museum R. C. S.), 176. Tubo-ovarian Cyst (Museum R. C. S.), 177. Double Hydrosalpinx (Beigel), of Rupture (Tait), PAGE 712 . 714 · 714 715 . 717 717 .' 721 738 · 744 178. Diagrammatic Section of Fallopian Tube, Representing the Two Directions 179. Ectopic Pregnancy (Museum R. C. S.), 180. Ectopic Pregnancy (Museum R. C. S.), 181. Ectopic Pregnancy (Museum R. C.S.), . 182. Intra-peritoneal Pregnancy (Wood), 745 746 • 747 771 . 777 • 778 779 796 • 183. Bilateral Laceration of Cervix (Skene), 803 184. Multiple Incomplete Laceration of Cervix (Skene), 803 • 185. Area of Denudation in Trachelorrhaphy (Thomas and Mundé), 186. Emmet's Cervical Scissors, 810 811 187. Scott's Uterine Scalpel, 811 188. Introduction of Sutures in Trachelorrhaphy, 812 and Vagina (Kelly), 194. Emmet's Double-curved Scissors, 189. Diagram of Vaginal Outlet, Showing Relations of the Levator, Rectum, 190. Injuries of the Pelvic Floor Shown Diagrammatically (Kelly), 191. Hypertrophic Elongation of Cervix Uteri (Museum R. C. S.), 192. Denudation and Disposition of Sutures in Complete Laceration of Peri- neum (Emmet), ... 193. Sims's Sharp-curved Scissors, 195. First Step of Perineorrhaphy (Skene), 196. Surface Denuded and Sutures in Position (Thomas), 197. Lines of Incision in Flap-splitting Operation (Mundė), 198. Lines of Incision in Flap-splitting Operation (Mundė), 199. Peaslee's Perineal Needles, • • 200. Flap-splitting Operation. Introduction of Sutures (Mundé), 201. Superimposed Diagrams of Fritsch's, Hegar's, Bischoff's, Simon's, and 817 818 821 824 826 826 827 828 Emmet's Operations, 202. Hegar's Operation, 203. Denudation in the Emmet Operation. Sutures Passed (Kelly), 204. Introduction of Sutures in Emmet's Operation. The Vaginal Sutures Tied (Thomas and Mundė), • 205. First Step of the Author's Subcutaneous Operation, . 206. Stoltz's Operation for Cystocele (Thomas and Mundé), 830 831 832 833 835 836 837 839 841 844 } ERRATA. "9 Page 205, 2d paragraph, 9th line, insert "the saliva” before " escaping.” Page 262, 3d paragraph, 8th line, read "prospect" for "prospects." Page 343, 1st paragraph, last word, read "source for "sources. "" Page 423, 3d paragraph, last line, read "afforded" for "offered." Page 450, 4th paragraph, 3d line, read "may" for "will." Page 468, 4th paragraph, 4th line, read "region" for "regions." Page 469, 2d paragraph, 5th line, read "inflammation " for "inflammatory symptoms." Page 472, 1st line, read " intra-peritoneal" for "intra-uterine." Page 612, 1st paragraph, 3d line, read "ten" for "two." Page 615, chapter heading, read "uterine fibromata" for " uterine fibroma." Page 628, 3d paragraph, 2d line, read "twenty" for “ puberty." Page 628, last paragraph, 3d line, strike out "per cent." Page 633, 4th paragraph, 2d line, read "are present" for "is present." Page 698, 6th paragraph, 5th line, read “suppurative" for "suppurating." Page 720, 1st paragraph, 3d line, read “she” for “the patient.” Page 720, 4th paragraph, last line, read "resort to both drainage of the cyst and abdominal drainage." Page 748, 3d paragraph, 3d line, omit the word "purulent." Page 817, 6th paragraph, 4th line, read "it" for "the injury.” xxiii A TEXT-BOOK OF GYNECOLOGY. CHAPTER I. THE CAUSES OF GYNECOLOGICAL DISEASES. Until our knowledge of pathology shall have become more accurate, no classification of the DISEASES OF WOMEN can be perfect. With the full consciousness of this fact I offer the following:- ETIOLOGY OF GYNECOLOGICAL DISEASES. I. Congenital. (a) Inherited feebleness of constitution; (b) Defects in or absence of development. II. Acquired. (a) Acquired feebleness of constitution ; (b) Reflex functional disturbance and nervous disorders; (c) Development of new growths and malignant disease; (d) Uterine displacements. III. Inflammatory. (a) Cellulitis ; (b) Peritonitis; (c) Metritis, ovaritis, salpingitis, cystitis, etc. 2 17 18 A TEXT-BOOK OF GYNECOLOGY. IV. Accidental. (a) Injuries resulting from pregnancy and parturition— I. Lacerations and cicatricial deposits; 2. Relaxations of the pelvic floor; 3. Uterine inversion; 4. Fistulæ, sloughing, closure of the os uteri, vagina, etc.; 5. Ectopic pregnancy; 6. Abortions; (b) Hematocele. Inherited Feebleness of Constitution.-As a race, the Amer- icans are essentially a nervous people. Quiet and recreation are unknown to the great majority of our population. The growth and development of a new country and the almost insane desire to amass wealth, afford the average American but little time for relaxation and enjoyment. Added to this, our peculiar climate stimulates the nervous system to an injurious. degree, and at the expense of nutrition. That our climate exerts a potent and harmful influence upon the nervous system there can be no doubt. Europeans, as is well known, cannot perform the same amount of mental work here as in their native country without paying the penalty. The researches of archæologists show conclusively that races now extinct have inhabited this hemisphere, and it is not unreasonable to believe that climate. has had much to do with the decay of these races. Unfortunately the husband is not the only victim in this war- fare of American civilization. He cannot, or does not, close his office door and lock his business behind. His wife and family participate in his anxieties and ambitions. As he ascends in the financial scale, new social obligations and demands force them- selves upon them. If reverses come, the mental worry and distress are still more injurious than the excitement incident to success. A child born under these circumstances is the inevitable victim of them. If the parents have inherited a constitution free from bias or disease the ante-natal influences may be over- come in after life; if, on the contrary, the parental impression is derived from organisms feeble and diseased, the offspring suffers THE CAUSES OF GYNECOLOGICAL DISEASES. 19 from the inexorable law of heredity. With a girl the odds will be against her from birth to the grave. Climate, social customs and education, unless her guardians are wiser than their age, will combine to stimulate her nervous system at the expense of her physical, and leave her ill-fitted to meet the demands of puberty, maternity, and the climacteric. Defects in or Absence of Development.-Under this head come the various anomalies of development with which the gynecologist every now and then meets and which are dealt with in detail in another chapter. Such anomalies are clefts of the urethra; double vagina with single or double uterus; arrest of uterine growth in embryo with or without a corresponding arrest of the ovaries; defects in the shape of the vagina and cervix; imperviousness of the hymen; entire absence of the vagina and the uterus; and distortions of the clitoris. The development of the uterus is probably much more influ- enced by the growth of the ovaries than are the ovaries by the uterus, so that after the ovaries reach a certain degree of develop- ment the further growth of the uterus is dependent upon them. (Emmet.) Unless the ovaries are sufficiently developed to per- mit of ovulation, the uterus is not properly stimulated, and an arrest of growth may occur at any time before this organ is fully developed. Later in life, our knowledge of the influence exerted by the ovaries or, according to Lawson Tait, the tubes as well, enables us to arrest hemorrhage and the growth of fibroids by their removal. Acquired Feebleness of Constitution.-The life of woman, more than of man, is characterized by metaphorical or develop- mental epochs, during which an unusual predominance is usually acquired by one or by several of the organs which, in their totality, make up the human body. These several epochs mark the transition of the neutral child into the woman, of the woman into the mother, and finally, when she has fulfilled her mission of child-bearing, of the mother into mature old age. With the exception of certain catarrhal diseases, the sexual * * An Introductory Lecture on the Diseases of Women. By James C. Wood, Medical Counselor, Vol. 10, p. 472. 20 A TEXT-BOOK OF GYNECOLOGY. organs of the girl before puberty are rarely if ever the seat of disease. So far as physical functions are concerned there is very little difference between the boy and the girl until the sexual faculties begin to assert themselves. As puberty approaches, however, there is the most remarkable difference in the constitu- tional sympathies of the opposite sexes. The sexual organs in the one play a comparatively subordinate part in the rôle of re- production; in the other the utero-ovarian functions are con- nected with every vital action from the evolution of puberty until the climacteric period, which terminates a distinctly sexual or reproductive life. (Ludlam.) The causes of acquired feebleness of constitution may be enumerated as follows: I. Deficient air and exercise; 2. Improper dress; 3. Exposure during menstruation; 4. Improper care during and after parturition; 5. Prolonged and undue emotional stimulation; 6. Marital irregularities. Deficient Air and Exercise.-The standard of health depends in no small degree upon the social stratum into which a girl is born or circumstances in after life may carry her. The imperious Goddess of Fashion demands a fair face and fair hands, two things incompatible with fresh air and proper exercise. The young girl as she approaches her teens is pro- hibited from taking the requisite amount of exercise because it is not genteel. If out-door sports are permitted they are not of such a character as to develop her physical system. As a result she passes into womanhood poorly fitted for the responsibilities which maternity will impose upon her. The birth of her first child often leaves her an invalid, if, indeed, some form of local disease superinduced before marriage, has not made her sterile. Improper Dress.--Corsets, low-necked dresses, and high- heeled shoes are responsible for much mischief and much of the business of the gynecologist. The short dress is discarded by far too early, and she who should remain a rollicking girl casts off her shoulder straps and constricts her waist with strings THE CAUSES OF GYNECOLOGICAL DISEASES. 21 and bands, thus crowding the abdominal organs into the pelvis. (Emmet.) As a result, the function of respiration is interfered with, the pelvic organs become displaced, the abdominal muscles atrophy, and freedom of movement is restricted. The lower extremities are at no time properly protected, and in evening dress the chest is likewise exposed. Add to this the injurious effects of high-heeled shoes,* and the fashionable woman of the period will do well if she escapes the penalty so often produced by causes constantly at work. Prevailing fashions and common customs, therefore, exert a most potent influence for good or for evil. Unfortunately there is an aping of the higher classes by the lower, and the evils of dress are therefore seen in every sphere of life and grade of society. We thus see that modifica- tion of form, disturbance of the functions of special organs, and alteration of single parts depend in no small degree upon the habit of dress. Exposure During Menstruation.-There is no physiological function imposed upon the female organism which is so liable to become pathological as is menstruation. This is not as it should be, yet it is in keeping with the refining and depressing influences of modern civilization. Menstruation should be as painless and as normal as defecation; and so we find it as we descend in the scale of evolution. The Indian girl, and, we are told, the negress in her native abode, do not suffer in the least, notwithstanding the fact that at all times they are subjected to the most severe exposure and exercise. Their systems have become inured to hardships by the environs, which have exerted a hardening influence, not only upon them, but upon their ancestors through countless generations. Indeed, evidence is to be had proving that the menstrual discharge was absent in their ancestors; that it developed with time because of a failure to gratify the reproductive instinct, and then became a habit. (Roussel, Auber.) Whether this statement be true or false, the influence of hard work and simple fare upon the quantity of hemorrhage is incontestable. The girl or woman reared prop- erly and endowed with a constitution such as she is entitled to * Gynecological Transactions, Vol. 7, p. 243. 22 A TEXT-BOOK OF GYNECOLOGY. as a birthright, can stand exposure during menstruation which would be decidedly hazardous to her more delicate sister. It is but a step from physiological to pathological congestion, and the next succession in the train of pathology is inflamma- tion. At each menstrual period a physiological congestion occurs, and in the great majority of women is associated with phenomena due to disturbed innervation and circulation. The system is in a susceptible state, and the congestion and irritation may extend to various parts of the body. If, either through necessity or recklessness, a menstruating woman goes lightly or improperly clad during the most inclement weather, the seeds of permanent disorder may be sown. The inflammatory dis- eases frequently originate in this way; oftener a serious dysmen- orrhea dates from such exposure. Certainly ordinary prudence suggests that during a time when all of the pelvic organs are intensely engorged, when the escaping ovule from the ovary has broken its surface, the woman should observe at least reason- able precaution. Nevertheless menstruation does not keep the average girl from the ball-room, even though it has to be sup- pressed by artificial means. To her the pleasures and conquests of a night are of greater importance than future health and happiness. Parenchymatous disease often follows an inflamma- tion thus excited, resulting in sterility and menstrual disorders which, acting through the sympathetic system, influence and deprave nutrition. Improper Care During and after Parturition.-Uterine contractions, from the very onset of labor, have a physiological mission other than the expulsion of the child. They consume the cell-elements of the enlarged uterus, and by compressing the nutrient vessels deprive them of oxidized protoplasm, which inaugurates fatty degeneration. These contractions continue even after the uterus is emptied, and give rise to the so-called after-pains." The protein substances resulting from the de- generation of the muscular fibers are converted into fats, which are absorbed. Eventually new cells appear upon the external layer of the uterus, from which a new organ is developed. (Schroeder.) With the growth of new cells the old and enorm- ously enlarged ones of pregnancy entirely disappear. In the THE CAUSES OF GYNECOLOGICAL DISEASES. 23 course of six weeks the uterus becomes normal in dimensions and weight, although remaining somewhat larger and more rounded than in nulliparæ. (Spiegelberg.) This process is called involution, upon the proper performance of which the woman's future health in no small degree depends. The phenomena appertaining to involution and to the puerpe- cal state would, under different circumstances, be considered pathological. Associated with the degeneration of muscular cells, thrombi are formed in the enlarged and torn vessels and the decidua is exfoliated. The size of the lymphatics is also exaggerated, which, together with the traumatism almost never absent, predisposes to septicemia, cellulitis, the formation of emboli, etc. These effects are immediate and must be dealt with accordingly. The remoter and more permanent ones have to do with perfect involution, which is only insured by proper care dur- ing the lying-in period. Uncleanliness during and after labor, and dragging the placenta from the uterus instead of expressing it by the more scientific method of Credè, are responsible for much that follows; failure to close rents and torn surfaces is equally reprehensible; and the prescribed nine days for "getting up" is a relic of the dark ages. Every woman is a law unto herself and should be so considered; what one may do with impunity may be the death of another. The size of the uterus, the persist- ence of the lochia, and the strength of the patient are the only scientific guides by which to gauge the period of absolute rest in bed. So long as the parturient womb can be felt above the pubes, by external examination, just so long is it unwise and unsafe for her to assume the erect posture. The increased weight will cause it to descend, thus interfering with the pelvic circulation, which, in turn, gives rise to congestion or inflamma- tion and often to permanent uterine displacement. The time is not far distant when the physician's success as an accoucheur will be judged, not by the length of time during which he keeps his patient at rest, but by the completeness of her recovery. The mammæ and uterus are sympathetically and almost mysteriously connected. This connection is one of the most useful designs of nature, and through it uterine involution is promoted. The application of the child to the breast excites 24 A TEXT-BOOK OF GYNECOLOGY. uterine contraction, and if this stimulation is withheld involution is apt to be incomplete. In the upper circles there is a tendency to relegate babes to wet-nurses and rubber nipples, and nature imposes her penalty for so doing. The system is soon taxed with the menstrual function, which should remain dormant for at least twelve months after confinement. Unless subterfuges, far more injurious than pregnancy itself, are resorted to, concep- tion is liable to occur before the system has fully recovered from the previous labor. From a purely physiological standpoint, every mother should nurse her child unless insuperable obstacles prevent; if it seems unwise to continue lactation during the usual period, it should at least be continued while involution is going on, if the counter-indications are not imperative. It will be seen that the best means of securing and promoting uterine contraction are vital and not mechanical. What is true of the uterus is also true of the over-stretched abdominal muscles and their coverings. The comeliness of the figure can- not be regained or preserved by a tight bandage-the curse of the lying-in chamber. Healthy muscles, whose function it is to contract under the command of the will, were never made stronger by non-use. The abdominal muscles are no exception to this rule, and if their movements are restricted by tight bandaging, atrophy is apt to result. Again, a bandage im- properly applied over an unnatural compress, forces the enlarged uterus into the pelvis and backward, causing a temporary if not a permanent displacement. This more often results if the dorsal posture is persistently maintained instead of permitting that position which is the most comfortable. When abdominal distention has been very great, and a moderately tight bandage affords a sense of relief, there can be no objection to applying it for a few hours or a few days; however, the practice of com- pressing the abdominal and pelvic organs for days and even weeks is not only the result of an exploded superstition but an actual injury. Reflex Functional Disturbance and Nervous Disorders.— The ganglionic system of nerves in women is more developed than in man, the great centre being the solar plexus. The gen- erative organs are surrounded by a reticulation of blood-vessels, THE CAUSES OF GYNECOLOGICAL DISEASES. 25 the smallest capillaries of which are in intimate contact with sympathetic nerve filaments. Each ganglion is in direct com- munication with the cerebro-spinal system through the spinal filaments which enter it. These two great nervous systems, though each is complete in itself, are, nevertheless, dependent one upon the other. They should work harmoniously together, and so they do if unmolested. An afferent impulse starting from the reproductive organs will induce, through the central nervous system, vaso-motor changes which will affect the pelvic circulation either favorably or unfavorably. (Foster.) It is in this way that many reflex phenomena are induced. When normally exerted, the influence of the sympathetic system on nutrition is a healthy stimulus to organic life. If, on the other hand, the stimulus becomes impaired, owing to local disease or irritation, reflex functional disturbance in some part of the body at once ensues. The morbid impression received by the sympathetic system is transmitted through the spinal nerves to the brain, which, in turn, transmits it to the special ganglion of the affected organ. The spinal nerve passing from this ganglion will convey pain to the seat of its distribution. (v. Chapter VIII.) These physiological facts, briefly stated, explain many symp- toms occurring in women which would otherwise remain enigmas. The extent of the reflex mischief produced by a local lesion depends less upon the nature of the lesion than upon the con- dition of the cerebro-spinal system. Every practitioner has met with many instances where women have gone for years with uterine displacements, cervical lacerations, etc., without the least inconvenience. In others, the slightest local disturbance may impress the system in the most profound manner. If lack of moral restraint and training, faulty education or, possibly, mental shock, has rendered the brain morbidly sensitive, the disturbance created by the organs of generation will fall with crushing force upon the cerebro-spinal system. Insomnia, hysteria, and even insanity result in this way; and pain in any and every part of the body may have its origin in the pelvis. Conversely, lesions in other parts of the body may react upon the generative organs. If there be a due proportion existing between the development of the nervous system and the 26 A TEXT-BOOK OF GYNECOLOGY. muscular, the equilibrium is not readily disturbed and local dis- orders may cause little or no impression. (Emmet.) With this knowledge of cause and effect as related to the diseases of women, the importance of preventing or removing the former before the latter can be reached is self-evident. It involves our system of education, which tends to create large brains and small bodies. The stimulation of the emotional faculties by improper literature is responsible for much mischief. No provision is made for the demands of approaching puberty— not the slightest relaxation from study or mental work. Co- education stimulates the girl to equal if not to excel her boy associates, upon whom nature imposes no physiological barriers in the form of menstruation; or, ill-governed and wretchedly ventilated boarding schools furnish a more superficial education at the expense of quite as much wear and tear of the nervous system. * The result is the same in either instance. Too often the girl exchanges a good constitution for a meaningless diploma. She is ill-fitted to become a wife and loath to assume the duties and responsibilities of maternity. She is advised to shirk the latter, and "conjugal onanism" is resorted to. Expe- dients and paraphernalia borrowed from the brothel are brought into requisition, and the marital couch is thus defiled. Should conception occur, men of "båttered reputations” stand ready on every hand to commit infant murder. (Goodell.) An im- perious instinct is denied gratification when the responsibilities of motherhood are shirked. As a result, the pelvic organs are left congested and the nervous excitement unappeased. Inflam- mation of the uterus and appendages with displacement and erosions are the inevitable sequelæ. The marriage relations bring pain instead of pleasure, and the mental distraction resulting therefrom is the cause of more than one separation * Let the reader remember that this chapter is devoted to the causes of gyneco- logical diseases. My long connection with the largest co-educational institution in the world leads me to speak with much emphasis. Nevertheless, I am not blind to the fact that the evils of existing systems leave their impress, to a greater or less extent, upon both sexes. I am a thorough believer in co-education. However, it should and can be inseparably associated with a system of physical culture which will develop brain and body simultaneously. J. C. W. THE CAUSES OF GYNECOLOGICAL DISEASES. 27 and divorce. I am not a pessimist, but a chapter devoted to the etiology of the diseases of women would be incomplete without touching upon an evil as insidious as it is far reaching. Development of New Growths and Malignant Disease.- We possess but little or no definite knowledge bearing upon the causation of most neoplasms, and particularly of those attacking the uterus. (Gusserow.) Virchow, Winckel, Cohnheim, Emmet and many others have put forth theories, all of which are imperfect. We are able to study the circumstances under which new formations develop; beyond this point we have not, up to the present time, succeeded in going. These include environs, nutrition, habits, age, race, state, etc. The commencement of many diseases, like the essence of life and death, as yet remain impenetrable. • The above circumstances as causative factors will be studied in other chapters. I shall, at this time, but briefly allude to the theory of congestion and hypertrophy so ably championed by Emmet, because it bears directly upon much that has already been said. According to this author, any cause that will keep up a more or less persistent congestion of the uterus will in due time excite a congestive hypertrophy of this organ; that, as a result, the nutrition of the parts becomes faulty and exaggerated; and as a consequence of this faulty nutrition, new growths originate, in the form of fibroma. Or, when the ovaries cease to perform their function, nutrition is diverted from the pelvis to other parts of the body, with resulting fatty degeneration of the uterus. Nutrition is now no longer occupied in the formation of new structures but in the removal of old. If some previous injury exists, it may be misdirected in its efforts to remove the products of such injury (hyperplasia, cicatricial tissue, etc.) and a neoplasm develops, frequently an epithelioma. Reasoning from analogy, this theory is the most plausible of any yet promulgated. It involves much pertaining to the habits of life which have already been discussed. Uterine Displacements.-Uterine displacements may be congenital as well as acquired. The congenital displacements are usually associated with some defect in the development of the organ, and the only bad symptoms resulting therefrom are 28 A TEXT-BOOK OF GYNECOLOGY. connected with the menstrual function and with generation. The acquired forms result from accident, congestion, inflam- mation, pregnancy, etc., and cause more or less local and general distress, depending upon circumstances. It is probable that the mere malposition of the uterus gives rise to but little if any suffering, unless the displacement is the result of accident, but that the suffering is due to secondary changes within the uterus and the pelvis. Such changes are congestion, chronic inflam- mation, hyperplasia, and displacement of the ovaries, all of which often excite reflex phenomena of the most distressing character. Disorders of the rectum and the bladder are likewise frequently due to uterine displacements. Inflammatory: Accidental.-The inflammatory and acci- dental causes do not demand at this time seriatim consideration. There is nothing obscure about them and since, as causative factors, they are recognized by all authorities, I will briefly present only a few general considerations. Salpingitis and the diseases of the Fallopian tubes have attracted much and wide attention during the last ten years. That the ovaries and tubes are responsible for much mischief, I am certain; and that many normal or curable ovaries and tubes have been sacrificed by over-zealous operators, I am even more certain. Unalloyed good rarely results from bold innova- tions made by men like Battey, Tait, and Heger. Operators with a reputation to make require material, and inexperienced diagnosticians too often ascribe obscure pelvic affections to the uterine appendages, which are accordingly removed. It is well that some of the older men have raised a protesting voice, for a beneficent operation is liable to fall into disrepute when per- formed with unwarranted frequency. The injuries resulting from pregnancy and parturition are countless. The more serious rents, uterine inversion, fistulæ, and adhesions force themselves upon the attention of all physicians. Cicatrices and relaxations of the pelvic floor, on the contrary, have not as yet received the attention which they deserve. In England and on the continent but a comparatively small number of specialists resort to Emmet's operation, or trachelorrhaphy, and those who do perform it have not mastered the originator's THE CAUSES OF GYNECOLOGICAL DISEASES. 29 technique. What is true of the cervix is also true of the perin- eum and pelvic floor. It will require another decade before the profession, as a whole, will have learned sufficient of cause and effect fully to comprehend the significance of the more obscure injuries within the pelvis. This brief survey of THE ETIOLOGY OF GYNECOLOGICAL DISEASES Shows conclusively, I think, the importance of the subject. Woman is subjected to those general diseases attack- ing both sexes indiscriminately; she is also a victim of causes, many of which are avoidable, to be sure, but many of which she cannot escape. Specialists will, therefore, ever be in demand; and the day is long past when the general practitioner can successfully "get on" with a mere smattering of gyne- cology. CHAPTER II. THE ANATOMY OF THE FEMALE PELVIC ORGANS. EMBRYOLOGY. I deem it unnecessary in a practical text-book on gynecology to discuss at length the subject of embryology. It is one belonging to obstetrics rather than gynecology. The following schema, prepared for my class in obstetrics, shows the success- ive steps in the early development of the ovum and the struct- ures from which various organs are derived. It will, therefore, prove useful in explaining some of the anomalies of develop- ment with which the gynecologist has to contend. The four layers formed by the blastodermic vesicle, viz., the ectoderm, two strata of mesoderm, and entoderm, are supposed to have the relations to the ulterior development of the body indicated in the schema, though some points bearing upon the subject are as yet unsettled. DEVELOPMENT OF THE OVUM, SHOWING SUCCESSIVE CHANGES FOLLOWING FECUNDATION. 1. Contact of spermatozoa with ovum, probably in the Fallopian Tube. 2. Disappearance of germinative vesicle. 3. Segmentation forming morula. 4. Changes in MORULA-formation of blastodermic vesicle. 5. BLASTO- I. Ectoderm-developing hair, nails, glandular structure of skin; the brain, spinal cord, organs of special sense, and genito-urinary organs. DERMIC VESICLE FORMS. II. Mesoderm.— 【 (a.) OUTER STRATUM-developing corium, mus- cles of trunk, and bony framework. (6.) INNER STRATUM-developing muscular and fibrous tissue of digestive tract, the blood, blood- vessels, and blood-glands. III. Entoderm-developing epithelium lining walls and glands of intestine. } Sembryonic spot. 6. AREA GERMINATIVA, composed of {(a.) area pellucida, in which appears the 7. EMBRYONIC SPOT-bisected by primitive trace. 30 THE ANATOMY OF THE FEMALE PELVIC ORGANS. 33 organs the labia minora are always in contact, as are the inner surfaces of the labia majora, except when the knees are widely separated. MUSCLES OF THE FEMALE PERINEUM. The Perineal Body (Fig. 2, P) is a pyramidal, wedge-shaped body occupying the space midway between the anus and the pos- terior vulvar commissure. It is the center of attachment for the transversus perinei muscle; the anterior end of the superficial sphincter muscle; the ligamentum ischio perinei-formed by the union of the superficial perineal fascia with the inferior border of the perineal septum ; the median fibers of the bulbo-cavernosus muscle; the perineal septum below the vagina; and the inner median fibers of the levator ani muscle. By a great accession of elastic tissue these several structures are fused together without altogether losing their identity, thus forming the perineal body. It measures 1½ inches vertically, the same transversely, and 3/4 of an inch antero-posteriorly. (Hart.) The Perineal Muscles are three in number on each side of the vaginal orifice, the transversus perinei (Fig. 2, 7), the bulbo- cavernosus (Fig. 2, 5), and the erector clitoridis (Fig. 2, 4). The Transversus Perinei arises from the ramus of the ischium and from the anterior aponeurosis of the perineal septum, and is inserted into the perineal body. The Bulbo-cavernosus (Fig. 2, 5) arises below from the perineal body and from the anterior aponeurosis of the perineal septum. It passes forward partially covering the bulb of the vagina, and is inserted into the corpus cavernosum of the clitoris, the posterior surface of the bulb and the mucous membrane between the clitoris and urethral orifice. (Henle.) The Erector Clitoridis (Fig. 2, 4) arises from the ramus of the pubis and the ischium and is inserted into the back and sides of the crus clitoridis. The Bulbi Vagina (corpora spongiosa urethra) lie on each side of the vaginal orifice resting on the triangular ligament and partly covered by the bulbo-cavernosus muscle. They consist 3 34 A TEXT-BOOK OF GYNECOLOGY. of masses of erectile tissue about 3/4 of an inch long, and anteriorly each blends with its fellow, this pars intermedia becoming continuous with the clitoris (Fig. 2, B). FIG. 2. S ģ C DISSECTION OF PERINEAL REGION. (Savage.) A. Anus; B. Bulb of vagina; C. Coccyx; L. Large sacro-sciatic ligament; P. Perineal body; v. Vaginal aperture; U. Orifice of urethra; g. Vulvo-vaginal glands. 1. Clitoris; 2. Its suspensory ligament; 3. Crura clitoridis; 4. Erector clitoridis muscle; 5. Bulbo-cavernosus muscle; 7. Transversus perinei muscle; 8. Sphincter ani externus; 9. Levator ani. The Vulvo-vaginal Glands (Bartholinian glands) lie in front of the posterior layer of the triangular ligament and close to the posterior end of the bulbi vaginæ. Each opens by a long duct at the sides of the hymen. (Fig. 2, g.) THE ANATOMY OF THE FEMALE PELVIC ORGANS. 35 THE FASCIAE OF THE PELVIC FLOOR. The Superficial Fascia of the pelvic floor consists of two layers-an upper one, which lies beneath the skin, more or less loaded with fat and is the continuation over the pelvic floor of FIG. 3. n SUPERFICIAL PERINEAL FASCIA; ANTERIOR VIEW. (Savage.) A. Anus; M. Urethral meatus and urethro-vaginal tubercle; H. Nymphæ; C. Clitoris; T. Tuberosity of ischium; c. Levator ani muscle; a. Anterior edge of gluteus maximus muscle; n. Neck of pudendal sac; O. Pudendal sac. the same structure which covers the abdomen, nates, and thighs; an under one, or deep layer, which forms a resisting membranous investment. The deep layer of the superficial fascia descends 36 A TEXT-BOOK OF GYNECOLOGY. from the abdomen over the pubis and covers the anterior peri- neal triangle down to its base, becoming attached to the outer margins of the ischio-pubic rami and to the lower margin of the septum or triangular ligament. The Pudendal Sac (Fig. 3, O) commences at the margin of the external inguinal ring and is formed by the deep layer of superficial fascia and the outer layer of the triangular ligament. It receives at its neck (n) the terminal fibers of the round ligament of the uterus. These sacs, one on each side of the vaginal orifice, usually contain more or less fatty tissue, and with their cutaneous coverings present themselves at the vulva as the labia majora. Inguinal hernias readily find their way into them and are then known as labial hernias. DEEPER FASCIAE. The Ischio-perineal ligament is formed by the union of the deep layer of superficial fascia with the lower border of the perineal septum. It is attached by its outer end to the ramus of the ischium and blends insensibly with other structures in the perineal body. The Perineal Fascia enclose the following structures from without inward :— Between the Skin and Superficial Fascia: Superficial peri- neal arteries and nerves; superficial hemorrhoidal vessels and nerves. Between the Deep Layer of Superficial Fascia and Anterior Layer of Triangular Ligament: Erector clitoridis; bulbo- cavernosus; transversus perinei; bulbs of the vagina; pu- dendal sacs; transverse perineal blood-vessels and nerves; venous plexuses; dorsal artery, and vein of clitoris. Between the Layers of Triangular Ligament: Urethra- in part; compressor urethræ; vagina-in part; pudic vessels. and nerves. THE ANATOMY OF THE FEMALE PELVIC ORGANS. 37 FIG. 4. DEEPER FASCIA OF THE FEMALE PERINEUM (TRIANGULAR LIGAMENT OR PERINEAL SEPTUM). (Savage.) a. Gluteus maximus muscle; L. Large sacro-sciatic ligament; T. Tuber ischii; c. Levator ani muscle; A. Anus, surrounded by b, Sphincter externus; d e, Transversus perinei and bulbo-cavernosus muscles crossed by a branch of pudic vein; both muscles partially removed to anterior aponeuroses of the perineal septum, m, and membranous investment of the bulb, 1; g. Anterior (lower) portion of Erector clitoridis muscle; n. Aponeurotic expansion of the upper portion on the crus; C. Clitoris and its musculo-membranous covering; M. Ure- thral meatus; v. Vaginal aperture; f. Muscular fibers belonging to perineal septum; 1. Bulb partially cut away. 38 A TEXT-BOOK OF GYNECOLOGY. THE PERINEAL SEPTUM, OR TRIANGULAR LIGAMENT. Note the Following Points.-The triangular ligament, or peri- neal septum, fills in the pubic arch and consists simply of two layers of fascia. These are termed anterior and posterior. They FIG. 5. U 3- 2 7 S P 5 PERINEAL SEPTUM, POSTERIOR VIEW, TOGETHER WITH THE PELVIC ATTACH- MENTS OF THE LEVATOR ANI MUSCLE. (Savage.) S. Inner surface of pubic symphysis; U. Urethra; V. vagina; 1. Pubic attachment of bladder; 2, 3. Pubic attachments of levator ani; 4. Pudic vein; 5. Urethro- pudal venous plexus; 6. Posterior face of the septum; 7. Median portion of levator ani, some of its inner fibers passing inward under the vagina, where, with the lower edge of the septum, they are comprehended in the perineal body. are attached externally to the greater part of the osseous margin of the pubic arch extending from the sub-pubic ligament in front to the beginning of the ischial tuberosity posteriorly. The upper fibers join those of the opposite side, so as to inclose the THE ANATOMY OF THE FEMALE PELVIC ORGANS. urethra. (Fig. 5, U.). 39 The lower fibers join those from the opposite side, below the vagina. The remainder of the septum resembles the coats of the vagina. In the reparation of injuries of the pelvic floor the triangular ligament plays a very important role. In Fig. 6 the pelvic fascia and their function are clearly shown by a perpendicular transverse section. 1 FIG. 6. b 2 Pm4 s3 PERPENDICULAR TRANSVERSE SECTION OF PELVIS THROUGH THE MIDDLE OF THE VAGINA. (Savage.) V. Vagina and its posterior column; O. Ischio-rectal fossa, filled with fatty process of superficial perineal fascia; I. Ischial tuberosity, section of; b. Inferior pelvic space; d. Recto-vesical layer of pelvic fascia; e. Inferior or perineal layer of levator ani fascia; n. Obturator fascia; p. Posterior aponeurosis of peri- neal septum; m. Anterior aponeurosis of same; s. Deep layer of superficial perineal fascia covered by fatty superficial layer; 1. Cross section of right crus clitoridis, including erector muscle; 2. Superficial transverse perineal mus- cle; 3. Bulb of vagina; 4. Muscle of perineal septum. THE PELVIC FLOOR DISSECTED FROM ABOVE. In Fig. 7 the Pelvic Floor is seen from above, showing its internal concave or peritoneal aspect. The peritoneum and underlying connective tissue is removed, together with the nerves and blood-vessels, exposing the so-called diaphragmatic muscles of the pelvis, viz.: the levator ani and the coccygeal. These 40 A TEXT-BOOK OF GYNECOLOGY. muscles, together with their investing fascia, form by all odds the most important support of the pelvic floor. The Levator Ani (2, 3, and 5, Fig. 7) has an extensive origin (the pubo-coccygeal and obturator coccygeal muscles of Savage). It arises from the posterior aspect of the pubis near the symphysis FIG. 7- 2. 8 3 C 5- P B G 7 -7 S A R -8 DISSECTION OF PELVIS FROM ABOVE. (Savage.) B. Neck of bladder; P. Symphysis pubis; V. Vagina; R. Rectum; C. Coccyx; S. Sacrum; A. Acetabulum; 1. Anterior vesical ligaments; 2, 3. Levator ani; 4. Ilio-pubic line of the latter; 5. Coccygeal muscle; 7. Pyriformis muscle; 8. Obturator muscle. in front, from the posterior surface of the ischial spine behind, and between these points from the "white line" of the pelvic fascia (Fig. 7, 4). From these attachments it sweeps downward and inward to become firmly attached to the walls of the vagina and the rectum and to the tip of the coccyx. Between the tip THE ANATOMY OF THE FEMALE PELVIC ORGANS. 41 of the coccyx and the rectum it blends with its fellow of the opposite side at the raphé. The series of fibers turning be- neath the rectum and vagina, intermixing with the lower circular fibers, form the "internal sphincter" and the “retractor vaginæ." (Luschka). The Coccygeal Muscles (Fig. 7, 5) one on each side of the pelvis, take their origin from the spine of the ischium. They pass inward, gradually expand into broad, thin laminæ, which are inserted into the lateral borders of the lower segment of the sacrum and to the sides and front of the coccyx. FASCIAL Coverings of the MUSCLES OF THE PELVIC FLOOR. The Pelvic Fascia, as viewed from above, is attached ante- riorly near the lower border of the symphysis pubis; laterally to the pelvic bone; and posteriorly to the spine of the ischium. At and between these attachments it follows the origin of the obturator muscles, is attached to the membrane of the obturator foramen, and posteriorly sends out a thin lamina that covers the sacral plexus and pyriformis muscle. From the "white line " the fascia extends downward and inward and is known as the recto-vesical fascia." This recto-vesical process covers a cor- responding surface of the levator ani muscle, becoming firmly attached to the vagina and the rectum, and giving off from its under surface fibrous sheaths which surround and follow these tubes downward. (Quain, Heath.) To the bladder processes are given off, which extend from the back of the pubis to the neck of the organ, forming the anterior ligaments; and fascial bands which are attached to the posterior lateral border of the vesical base, forming the lateral vesical ligaments. (C If the student will now turn to Fig. 8 he will see, diagram- matically, every detail of the construction of the pelvic floor. In studying this diagram he should bear in mind that the female floor is pierced by the vagina and the rectum, which tends to weaken it. He should remember, however, that the vagina is a mere mucous slit in the pelvic floor, whose walls are in appo- sition. In the upright posture it makes an angle of about 60° with the horizon, which is nearly parallel to the pelvic brim. Pis the section of the body of the pubic bone; c is the pubo- 42 6 5 7 A TEXT-BOOK OF GYNECOLOGY. FIG. 8. 444 P 24 3 PERPENDICULAR SECTION, FROM BELOW UPWARD, TO THE LEFT OF THE PUBIC SYMPHYSIS, DIVIDING THE LABIUM THROUGH THE MIDDLE OF THE PUDEN- DAL SAC. Vide text. (Savage.) 3. 2- A FIG. 9. ક 5 P THE RELATIONS OF THE MUSCULAR FLOOR OF THE PELVIS TO THE PRESEN- TATION AT THE LAST STAGE OF PARTURITION. 1. Upper margin of the vaginal ring; 2. Infra-vaginal portion of triangular ligament and transversus perinei muscle; 3. Their attachments to the tuberosity of the ischium; 4. Lower part of levator-ani muscle; P. Perineal body; A. Anus. THE ANATOMY OF THE FEMALE PELVIC ORGANS. 43 ischiatic line (white line, Fig. 7) between the pelvic fascia and obturator fascia, to which the levator ani is attached laterally; d is the recto-vesical fascia covering the levator ani muscle; p is the posterior layer of the triangular ligament (perineal septum); m, anterior layer of triangular ligament; s, under layer of superficial perineal fascia; o, ischio-rectal extension of r, mass of fatty tissue filling pudendal sac, and receiving the termination of the round ligament, and fatty layer of superficial perineal fascia. 1. Sheath of deep layer of superficial fascia surrounding the crus clitoridis and its erector muscle; 2. Transverse perineal muscle; 3. Bulb of vagina; 4. Lower muscular fibers of perineal septum extending between and m; 5. Gluteus maximus mus- cle; 6. Ischio-sciatic ligaments; 7. Pyriformis muscle. The relation of the muscular floor of the pelvis to the pre- sentation at the last stage of parturition is well shown in Fig. 9. It will be seen from this illustration how it is possible to have those structures of the pelvic floor which afford its main support- the diaphragmatic muscles, their fascia, and the triangular liga- ment-relaxed and separated without any external injury to the perineal body. Unless the student fully comprehends this fact he cannot intelligently repair injuries of the pelvic floor. THE RELATIONS OF THE FEMALE PELVIC ORGANS WITH THE PELVIS AND WITH ONE Another. Fig. 10 represents a median perpendicular section of the pelvis from front to back, and shows both pelvic spaces. For the purpose of illustration, the urethra, bladder, vagina, and rectum are represented with their walls separated. This is erroneous, for when empty the walls of all of these organs lie in apposition. PERITONEUM. The Pelvic Peritoneum Traced from Before Backward.- At a point a little above the symphysis pubis the peritoneum of the anterior abdominal wall is reflected to the bladder (Fig. 12). From the fundus it dips down between the bladder and the uterus to a point corresponding to the internal os; thence over the anterior surface of the uterus. It forms between the 44 R B P A TEXT-BOOK OF GYNECOLOGY. FIG. 10. V 14 C m L 1 MEDIAN PERPENDICULAR SECTION OF PELVIS. (Cazeaux.) S. Section of pubic symphysis; B. Bladder, moderately distended; in front its outer longitudinal coat passes off to the inferior edge of the pubic symphysis and to the ligamentous process of the levator ani muscle, where it is attached; it bridges over the urethro-pubic venous plexus, separating that space from the vesico-pubic space above, which in turn is bridged over by the vesical ligaments formed by the urachus and two remnants of the hypogastric arteries. The internal circu- lar muscular coat of the bladder is well shown. The internal mucous folds loosely adhere to the lining membrane and cover the lattice-like projections of the inner circular coat into the vesical cavity. The entrance of the left ureter is indicated by a black point. u. Urethra. The inner longitudinal muscular coat is surrounded by m, m, outer circular coat. The muscular layers at u consti- tute a true compound sphincter, composed of organic and voluntary muscular fibers. C. Section of clitoris; L. Left labium; I. Left nympha; V. Vagina. Its muscular coats blend with the tissues of the uterine neck. The long axis of the uterine cavity is nearly at right angles with that of the vagina. P. Perineal body. The many small vessels are indicated by black dots. The anterior sec- tions of the lower muscular fibers of the rectum (internal sphincter) are immedi- ately behind it. A. Anus, showing the columns of Morgagni; R. Rectum, show- THE ANATOMY OF THE FEMALE PELVIC ORGANS. 45 bladder and the uterus the vesico-uterine pouch and the vesico- uterine ligament. From the anterior surface of the uterus it passes over the FIG. 11. U A.II.. VUO R P C A VC. Ur HORIZONTAL SECTION OF THE ABDOMEN, SHOWING THE PELVIC ORGANS FROM ABOVE AND THE PELVIC CAVITIES. V. Fundus of bladder moderately distended; U. Uterine body; A. H. Hypogastric artery; D. Cul-de sac of Douglas; A. Aorta; V. C. Vena cava; Ur. Ureter; P. Psoas muscle; R. Rectum. (Auvard.) fundus, covering completely the posterior surface and descending for about one inch (variable) on to the posterior vaginal wall. ing the valves of Houston projecting into its cavity. All of the coats of the rectum are included in these folds; they disappear entirely upon slight distention. The internal sphincter (inferior circular fibers) are indicated by minute circular markings; the posterior half of the external sphincter is indicated by lines near the coccyx. U. Left half of uterus retrodisplaced. Its central and more vascular portion is indicated by black dots around which are its internal and external muscular coats. P P. Vesico-uterine and recto-uterine (Douglas's pouch) peritoneal folds. 46 A TEXT-BOOK OF GYNECOLOGY. From this point it is reflected over the anterior surface of the rectum, forming the pouch of Douglas. (Figs. 10 and 11.) The Pelvic Peritoneum at the Sides of the Uterus.- The two layers of peritoneum covering the anterior and posterior FIG. 12. d a FROZEN SECTION, SHOWING PERITONEUM, WHICH IS INDICATED BY DOTTED LINES. a. Anus; b. Vagina; c. Bladder; d. Uterus; e. Below Douglas's pouch; f. Sym- physis pubis. (Furst.) surfaces of the uterus lie nearly in apposition at the sides of the uterus, from which point they extend on either side outward and somewhat backward to the sacro-iliac synchondrosis; at this point they pass to the side walls of the pelvis. These two layers of peritoneum form the broad ligaments. THE ANATOMY OF THE FEMALE PELVIC ORGANS. 47 The Broad Ligaments enclose between their two laminæ of peritoneum, lymphatics, blood-vessels, connective tissue, and unstriped muscle. The Fallopian tubes are placed just within their upper face margin. At the outer margin of the ligament there is a portion (one inch) not occupied by the Fallopian tube, which is the infundibulo-pelvic ligament of the ovary. The ovary projects through the posterior lamina of the broad liga- ment; enclosed in the two laminæ, between the ovary and ampulla, is the Parovarium. At the uterine end of the broad ligament, near its upper angle, there is a longitudinal fold of peritoneum into which the unstriped muscular fibers of the uterus are prolonged. It extends from the upper angle of the uterus to the inner end of the ovary (one and one-fifth inches) and constitutes the Ovarian Ligament. The Pelvic Peritoneum Reflected from the Sides of the Pelvis. At the sides of the pelvis the peritoneum descends and is reflected on to the lateral surfaces of all of the pelvic organs. At the lower lateral part of the body of the uterus it forms two folds which extend outward and backward toward the second sacral vertebra. These folds contain connective tissue and unstriped muscular fiber, and constitute the Utero-sacral liga- ments. (Fig. 11.) Practical Points Concerning the Pelvic Peritoneum.-I. There is no break in the continuity of the peritoneum, although described in sections. 2. In operations involving the posterior vaginal fornix it is an easy matter to open into the peritoneum. There is no opera- tion involving the anterior fornix which endangers the peri- toneum. 3. When the bladder is distended, and during parturition, the organ can be penetrated above the pubis without injuring the peritoneum. THE ROUND LIGAMENTS OF THE UTERUS. The Round Ligaments are the only uterine ligaments not described in tracing the peritoneum. They vary in length from four to five inches. Within the pelvis they are attached immedi- 48 A TEXT-BOOK OF GYNECOLOGY. ately below and in front of the Fallopian tubes. A portion of each ligament is included in the anterior fold of the broad ligament, from which it passes, enveloped in a fold of peritoneum, to the internal inguinal ring, having the same relations as the sperma- tic cord in the male. After emerging from the external ring it FIG. 13. U N E 1 T 5 P 4 PUBIC TERMINATION OF ROUND LIGAMENTS. (Savage.) U. Fundus uteri; P. Pubis where covered by pubic portion of aponeurosis of int. obliq. muscle; L. Uterine extremity of round ligament; E. Aponeurosis of ex. obliq. muscle; i. Internal oblique muscle; 7. Rectus muscle; N. Genital branch of genito-crural nerve; 1. External terminating fibers of round ligament into outer pillar of internal ring near Gimbernat's ligament; 2. Internal terminating fibers into conjoined tendons of int. obliq. muscle and transversalis muscle near pubis; 3. Middle terminating fibers into upper part of external ring; 4. Internal pillars of external ring; 5. Vessels of round ligament, nervous filaments, and middle terminal fibers of round ligament descending into pudendal sac. passes very close to the outer side of the pubic spine, into the fibrous tissue of the mons and the upper portion of the labium majus. Before passing into these structures it is broken up into several fine strands. (Fig. 13.) A number of operations upon the round ligaments have recently been devised for overcoming uterine displacements. THE ANATOMY OF THE FEMALE PELVIC ORGANS. 49 THE PERITONEAL PELVIC POUCHES. The Vesico-uterine Pouch lies between the bladder and the uterus and contains no small intestine. (Fig. 14.) The Paravesical Pouches lie one on each side of the bladder in front of the broad and infundibulo-pelvic ligaments. They probably contain intestine when the fundus is diverted to the front, and certainly do when it is displaced posteriorly. The Fallopian tubes also lie in these pouches. PERITONEUM HADAD LIGH FIG. 14. RECTUM OUND LIG UTERUS TOAD LIG UTERO-VESICAL LIOS BLADDER PERITONEUM THE POUCHES AND REFLECTIONS OF THE PELVIC PERITONEUM. (Hodge.) The Lateral Pouches of Douglas are bounded in front by the broad ligaments; laterally by the pelvic walls; and poste- riorly by the utero-sacral ligaments. The Pouch of Douglas or Posterior Cul-de-sac is bounded anteriorly by the uppermost inch of the posterior vaginal wall and posterior aspect of the supra-vaginal portion of the cervix; superiorly and laterally by the utero-sacral ligament; and pos- teriorly by the sacrum and rectum with their peritoneal invest- 4 50 A TEXT-BOOK OF GYNECOLOGY. ment. When the uterus lies in front it is partially filled with intestine, which is crowded out when it is retroverted or retro- flexed. The depth of the pouch of Douglas varies. Normally it descends for about one inch on to the posterior aspect of the pos- terior vaginal wall. It is greater on the left side than on the right. Pirogoff has made a section in which the peritoneum dips down on the posterior vaginal wall till within about an inch from the vaginal orifice. This occasional anomaly should be borne in mind by the operator. CELLULAR OR CONNECTIVE TISSUE OF PELVIS. This includes the fascia, which is described in connection with the muscles of the pelvic floor; and the loose cellular or connec- tive tissue throughout the pelvis. The Cellular Tissue fills in the spaces between the bladder, uterus and rectum above, and surrounds the vagina and rectum below, spreading out between the layers of broad ligament. It passes by continuity from the bladder and uterus upward into the iliac fossa, along the surface of the psoas muscle posteriorly, and between the peritoneum and transversalis fascia anteriorly. It is very scant between the anterior and posterior surfaces of the peritoneum, but at the sides of the cervix exists as distinct, loose tissue. It is most abundant between the folds of broad liga- ments. The pelvic cellular tissue acts as a cushion in breaking the force or jar which would be felt with every step. It steadies the pelvic organs, and from its peculiar web or sponge-like forma- tion permits the blood-vessels and nerves to pass through it to their distribution. It admits also of much displacement of the pelvic organs either upward or downward (as in pregnancy and prolapsus) without injury to the structures which pass through it. This tissue is of the highest importance pathologically, because of its liability to inflammation. THE ANATOMY OF THE FEMALE PELVIC ORGANS. THE UTERUS AND ITS ANNEXA. FIG. 15. 17 V- T R 51 UTERUS AND ANNEXA. C. The uterine neck; L. L. Left broad ligament; L. L. Part of right broad ligament; M. Right ovarian ligament; O'. Right ovary; P'. P. Fimbriated extremities of Fallopian tubes; R'. R. Round ligaments; T'. T. Fallopian tubes; U. Anterior surface of uterine body; V. V. Vagina. THE UTERUS. The Uterus is placed between the bladder and the rectum. Its anterior surface is almost straight, and its posterior convex at its upper part. It is divided into body and cervix. On making a coronal section (Fig. 16) the uterine cavity is best seen. The cavity of the body is a triangular slit with its apex downward. It is lined with mucous membrane and con- tains three openings-those of the Fallopian tubes and the os internum. The Cavity of the Cervical Canal is conical or spindle- shaped, and has two openings into it-the os externum from below, and the os internum from above. 52 A TEXT-BOOK OF GYNECOLOGY. The average length of the unimpregnated uterus, from the os externum to the exterior of the fundus, is three inches. The average length of the uterine canal, from the os externum to the interior of the fundus, is two and a half inches. The Cervix is divided into a vaginal and a supra-vaginal por- FIG. 16. CORONAL SECTION OF UTERUS THROUGH FALLOPIAN TUBES. (Savage.) a. Uterine cavity; b. Canal of the cervix and its peculiar folds of lining membrane; d. Internal uterine coat; c. Os externum; e. Uterine aperture of Fallopian tubes; f. Fallopian tubes; g. Broad ligament; V. Vagina. tion. The vaginal portion lies within the vagina. Upon digital examination the os externum is felt as a mere dimple in virgins; in women who have borne children it is transverse and fissured. In structure the uterus is composed, from without inward, of peritoneum, unstriped muscular fibers, and mucous membrane. THE ANATOMY OF THE FEMALE PELVIC ORGANS. 53 THE FALLOPIAN TUBES. The Fallopian Tubes (Fig. 17) run sinuously from the upper angle of each side of the uterus, and are inclosed in the upper free margin of the broad ligaments. They vary in length from four to six inches, the right being usually the longer of the two. Each tube is composed of three parts-the isthmus, the ampulla, and the pavilion. J FIG. 17. a VIEW FROM BEHIND OF THE LATERAL ANGLE OF THE UTERUS, WITH PART OF THE LEFT BROAD LIGAMENT, OVARY AND PAROVARIUM. (Henle.) a. Uterus; b. Isthmus of Fallopian tube; c. Ampulla; g. Has Parovarium to the right, and fimbriated extremity of Fallopian tube and ovarian fimbria just below it; e. Ovary; f. Ovarian ligament; 2. Infundibulo-pelvic ligament. The Isthmus is the uterine end of the tube. It is narrow and straight, and its lumen will barely admit a bristle. The Ampulla is curved and thick, with a lumen sufficiently large to admit an ordinary sized sound. The Pavilion (fimbriated end) is expanded into a funnel- shaped extremity. In structure the Fallopian tube is composed, from without in- ward, of peritoneum, longitudinal and circular unstriped muscu- lar fibers, and mucous membrane lined with ciliated columnar epithelium. 54 A TEXT-BOOK OF GYNECOLOGY. THE OVARIES. The Ovaries are two oval-shaped bodies which project through the posterior layers of the broad ligaments, one on either side of the uterus. They vary in weight from sixty to one hundred and thirty grains, and in length from one to one and one-half inches. The ovarian ligaments have been described with the peritoneum. In structure the ovary is composed of peritoneum, connective tissue, unstriped muscular fibers, blood-vessels, nerves and lym- phatics. The peritoneum is of a dull luster and is covered with an epithelium made up of columnar nucleated cells, which is known as germ-epithelium. The connective tissue consists of two layers-the cortical and the medullary. The cortical lies beneath the peritoneum and the medullary near the hilum. Throughout the connective tissue are innumerable Graafian Follicles varying in size from in. As they advance toward and bulge from the surface they become much larger than this and in due time rupture. The Graafian follicles consist of— (a) A tunica fibrosa (Ovicapsule); (6) A membrana propria ; 1 30 (c) A layer of nucleated columnar epithelial cells—(Membrana Granulosa); (d) Liquor folliculi. The Membrana Granulosa projects into the liquor folliculi at one point, which is known as the discus proligerus. The discus proligerus contains the ovum, which has the following structure:- (a) Zona pellucida, or external envelope; (6) Yelk protoplasm; (c) Germinal vesicle (7 (d) Germinal spot (0 3 in. diameter); in. diameter). THE VAGINA. The Vagina connects the external and internal organs of generation, and extends from the hymen to the cervix uteri. It is bounded anteriorly by the bladder and urethra, and posteriorly THE ANATOMY OF THE FEMALE PELVIC ORGANS. 55 * by the perineum, rectum and lower inch of the cul-de-sac of Douglas. The Anterior and Posterior Vaginal Walls are continuous at their sides and lie in apposition, so that the vagina is a mere slit in the pelvic floor. In the upright posture it is nearly par- allel to the pelvic brim (Fig. 18). The Anterior Vaginal Wall is from 2 to 2½ inches long, forming at its junction with the cervix the anterior vaginal fornix. It is sepa- rated from the posterior wall of the bladder by loose connective tissue, but it is closely incorporated with the urethra. The Posterior Vaginal Wall is more than an inch longer than the anterior, forming at its junction with the cervix the posterior vaginal fornix. In Structure the vagina consists of mucous membrane, and two layers of unstriped muscular fibers surrounded by loose connective tissue, which contains its outer venous plexus. The mucous mem- brane is made up of unstriped muscular fibers, elastic tissue, con- nective tissue, and epithelium (squa- mous and cylindrical). C....... FIG. 18. し ​ ď VAGINA IN VERTICAL SECTION. (Hart.) a. Perineum; b. Urethra; c. Vagina; e. Anterior lip of cervix; f. Os uteri. The axis is not normal at its upper part, as the uterus was drawn back. The Bladder, Urethra and Rec- tum are well shown in Fig. 10. The relation of the ureters to the uterus and bladder cannot, however, be shown in either a vertical or horizontal section of the pelvic organs. Since vaginal hys- terectomy has become a popular and frequent operation a knowl- edge of the exact location of the ureters is very important (Fig. 19). In the upper part of the pelvis they lie nearly parallel until they cross the iliac arteries. The left ureter lies behind 56 A TEXT-BOOK OF GYNECOLOGY. the sigmoid flexure and the right behind the lower end of the ileum. After crossing the iliac arteries they extend along the lateral walls of the pelvis downward, backward, and outward, nearly to the spine of the ischium. At this point they bend forward and inward, behind the uterine vessels, and pass beneath the base of the broad ligaments, entering the bladder from one-half to three-quarters of an inch in front of and below the cervix. FIG. 19. C L U R A B RELATIONS OF THE URETERS AT THE LEVEL OF THE OS INTERNUM, AS SEEN FROM ABOVE. (Polk.) U. Uterus; B. Bladder; R. Rectum; A, A. Uterine Arteries; C, C. Ureters; L. L. Utero-sacral ligaments. There are three openings into the bladder-the orifices of the two ureters and the internal orifice of the urethra-dividing it into neck, base, and body. The ureteric openings are separated from each other by an inch or an inch and a half. All above these openings and the centre of the symphysis is the body; all below is the base; and that triangular portion bounded by them and the internal urethral orifice is the trigone. Practical Observation: In vaginal hysterectomy, and in all operations involving the broad ligaments, there is but little danger of injuring the ureters in securing the base of these THE ANATOMY OF THE FEMALE PELVIC ORGANS. 57 ligaments, if the operator applies the ligature or clamp close to the cervix. THE BLOOD-VESSELS, LYMPHATICS AND NERVES OF THE PELVIS. Blood-Vessels.-(v. Plate I.) The entire blood supply of the pelvic organs and perineum is derived from the ovarian, uterine, vaginal, and internal pudic arteries. The ovarian is a branch of the abdominal aorta; the last four are all branches of the anterior division of the internal iliac. At the isthmus of the cervix a special branch of the uterine joins with its fellow to form the circular artery. The venous supply is very abundant and consists of numerous and freely communicating plexuses. These plexuses are located as follows:- The Vesical Plexus, external to the muscular coat of the bladder. The Hemorrhoidal Plexus, below the mucous membrane of the lower part of the rectum. The Vaginal Plexuses-one outside of the muscular coat and one in the sub- mucous tissue. The Uterine Plexus, in the muscular structure of the uterus. The Ovarian Plexus (pampiniform plexus), between the folds of the broad ligament. Vast Venous Plexuses lie between the layers of broad ligaments and beneath the peritoneum. Nerves. The pelvic organs are supplied with both spinal and sympathetic nerves as follows:- a. Spinal 1. Inferior hemorrhoidal branch of pudic and fourth and fifth sacral and coccygeal nerves supply the levator and sphincter ani muscles. 2. The fourth and fifth sacral and coccygeal supply the coccygeal muscles. 3. The pudic supplies muscles of the perineum and the clitoris. b. Sympathetic.-Inferior hypogastric plexus gives off branches to the vagina, uterus, Fallopian tubes, and ovaries. The nerves terminate in the muscular layers of the uterus in the nuclei of unstriped muscle (Frankenhäuser). Those supplying the mucous membrane end in ganglia (Hart). Lymphatics. The lymphatic system of the pelvic organs is very extensive and very important. The vessels are arranged in a network surrounding the various structures and organs, and freely communicate with the inguinal and pelvic glands. For a more extended description of the lymphatic system, the reader is referred to the special works of Hart and Savage. (v. Fig. 173). CHAPTER III. CASE TAKING. Systematic inquiry should precede a local examination of the female pelvic organs. It is, however, unwise for the physician to restrict the patient's narrative by confining her to one of the many case-records now in existence. A voluntary history is of more value than one obtained by a series of cross-questions. The average patient's imagination is influenced by set questions. She should be permitted first to relate her own story, and as much of it as the physician deems important he should note. This will afford him a superstructure upon which to base a more systematic examination. A faultless clinical record has not yet been published. For the last five years I have used Miner's, and, although imperfect, it possesses the merit of preventing the examiner from confining himself to one set of organs, for the general schedule is very complete. The gynecological form, as modified by me, is as follows: Menstrual and Marriage Data. First Menstruated at- Character of pains at this time (a) before flow; (b) during flow; (c) after flow- (d) Became regular after— (e) Duration of flow ; (ƒ) quan- tity- (g) Time of change to more pain; or (½) less pain— (i) Time of flow when most pains- (j) Character of pains- (k) Quantity increased at this time; or (7) diminished; (m) flow lasting- Present Menstrual condition, (n) Interval; (0) duration of flow; () quantity; (9) time of most pains- (r) Character of pains; (s) Special remarks— MARRIAGE DATA. No. of children and ages- No. of Miscarriages- Last Miscarriage occurred- Last Labor lasted- Special incidents of this or any other Labor- Character of Recoveries- PRESENT CONDITION. (Menstruation and Leucorrhea above.) Development of Present Known Causes— Symptoms- Nervous Derangements- Leucorrhea since— Its character, quality and source- 58 CASE TAKING. 59 Irritability of Bladder- Constipation- Special pains, locality Inflammation of- and degree- Os, size of- Pains increased by- PHYSICAL EXAMINA- TION. Vagina-Size and tenderness- Prolapse of Walls- Erosions of- Douglas's pouch- Vaginal vault- Cervix Uteri- Size and position- Flexures- Laceration of— Uterus-Mobility- Position- Flexure Enlargement- Ovaries- Tubes- Broad ligaments- Pelvis- Density- Secretion- Ulceration of— Abrasion- Vaginal discharge- (a) Character; (b) amount; (c) persistence; (d) duration- General- Diagrammatic outlines of the pelvis, so arranged that special lesions can be quickly indicated, add greatly to the value of a gynecological record. THE SIGNIFICANCE OF PAIN IN DIAGNOSIS. One or all of three general symptoms usually induce the non- pregnant female to submit to a local examination. These are some unnatural discharge from the generative tract, disordered menstruation and pain. Pain, as an expression of disease, may mean much or little, and the importance of interpreting its significance correctly is self-evident. For the convenience of study, it may be classified as follows:- As Regards Location.—1. Lumbar region; 2. ovarian region; 3. hypogastric region; 4. sacral and coccygeal region; 5. vulvar region; 6. lower extremities; 7. general. As Regards Function.-I. Menstruation; 2. defecation; 3. micturition; 4. coition. As Regards Posture.-I. Erect; 2. sitting; 3. reclining. • AS REGARDS LOCATION. Lumbar Region.-Pain in the back is a symptom which is perhaps oftener complained of in uterine disease than any other. * 60 A TEXT-BOOK OF GYNECOLOGY. It may be the only manifestation of such disorder and is, pro- bably, purely reflex. That it is not due to pressure is evident from the fact that it is found when the fundus is directed forward as well as backward, and in various lesions of the pelvic organs giving rise to no pressure. It nevertheless occurs oftener in retro- displacements and particularly in retroflexion. Expulsive efforts of the uterus will likewise excite lumbar pain, hence it is a symp tom of the obstructive form of dysmenorrhea, and occurs when- ever the uterus contracts upon any foreign body or substance. Prolapse of the ovary and lesions of the cervix and endometrium, may also cause a most persistent backache. Lumbar pain is to be differentiated from- 1. Lumbago; 2. Disease of the vertebræ ; 3. Disease of the kidneys; 4. Abdominal aneurism. In lumbago muscular effort is painful; the patient finds it diffi- cult to stand erect, and even impossible to stoop forward. The onset is often sudden and it is uninfluenced by either emotion or menstruation. The clinical history in disease of the vertebra is important; that of traumatism or constitutional bias is rarely absent. There is usually tenderness upon pressure over the affected part, and other local evidences of deformity and disease. When kidney disease is suspected the only safe guide is a care- ful examination of the urine. Abdominal aneurism is a disease of middle life and occurs. more often in males. The physical signs of aneurism are rarely wanting. Finally, menstruation aggravates nearly, if not all, pelvic lesions, but does not influence the other affections under consideration. Ovarian Region.-Few authors agree with Hewett that pain in the groin is, in ninety per cent. of all cases, due to anteflexion. It is more probably due, in the vast majority of instances, to irritation or inflammation of the ovary. In character it is sting- ing or burning, sometimes aching, more or less persistent, and usually confined to one side-oftener the left. It is particularly CASE TAKING. 61 distressing a day or two previous to menstruation, during exer- cise and after congress. Not infrequently it can be traced to sexual irregularities and is, therefore, often met with in prosti- tutes. Sometimes it occurs at regular intervals between the menstrual periods, the result, according to Priestly, of "inter- menstrual" ovulation. Bermetz, DeMerie, and Noeggerath be- lieve gonorrheal infection to be a prominent causative factor. In certain instances uterine displacements and lesions will cause reflex pain in the ovarian region, though oftener it is the result of ovarian congestion and inflammation which follow in the train of such lesions. Hypogastric Region.-Pain in this region varies greatly in character. It may be— 1. Bearing-down; 2. Intermittent; 3. Persistent; 4. Inflammatory; 5. Pain with symptoms of shock and collapse. Bearing-down pain located in this region is suggestive of one of several conditions, and, if persistent, calls for an exploration of the pelvic organs. The most frequent cause is, undoubtedly, the contraction of the uterus upon something within its cavity or walls, when it is expulsive as well as bearing-down. Fibroid tumors, polypi, retained menstrual blood, and a detached ovum all excite the uterus to an unnatural contraction. Any disease of the uterus involving change or shape of the organ may like- wise cause a bearing-down pain. Such are the various forms of displacement, particularly descensus with or without vaginal prolapse; hypertrophic elongation of the cervix; and hyper- plasia of the uterine body. Hematocele as a cause of bearing- down pain will be considered under another head. The most typical intermittent pain is that of normal labor. It then comes and goes at regular intervals, with a decided period of intermission. Pains simulating those of labor occur in abor- tion and are not infrequently present in the non-pregnant. For diagnostic purposes we may consider: (a) Pain resulting from retained menstrual discharge; (b) pain due to the expulsion of 62 A TEXT-BOOK OF GYNECOLOGY. • an ovum or retained fetal membranes; (c) pain due to retention of urine; and (d) pain due to tumors of the uterus. In pain resulting from retained menstrual discharge, the history will usually assist us in forming an intelligent conclusion. In young girls the escape of blood externally may never have taken place. If the menstrual discharge is retained, all of the symp- toms of menstruation will recur at regular intervals, minus the flow. The suffering is usually great, hysterical phenomena are rarely absent, and, in due time, enlargement of the uterus may be felt. A local examination will reveal an atresia, either of the cervix or vagina, which is usually congenital. In women who have menstruated the symptoms are similar, but the obstruction, which may be temporary or permanent, is generally acquired. If temporary, persistent contraction will overcome it; the uterus will then be emptied and the pain will cease until the organ is again distended. This type of obstruction is often the result of flexion. 2 Intermittent pain due to the expulsion of an ovum or retained fetal membranes has a history which, if elicited, will rarely mis- lead a careful examiner. The patient will state that the menses have been suppressed for one or more periods. With such a history, and the discharge of blood suspiciously excessive, a vaginal examination is imperative. The discharges should be carefully examined for the products of conception, though it must be remembered that in very early abortion these may be entirely overlooked. Velpeau detected an ovum of about four- teen days, which was not larger than an ordinary pea. It is entirely possible for both conception and abortion to occur be- tween two menstrual periods, when the diagnosis would be exceeding difficult, if not impossible. Retention of urine has caused intermittent pains, simulating those of labor (Sedgwick). In the majority of instances such retention follows labor, and is due to paralysis of the walls of the bladder. In Dr. Sedgwick's case, however, it occurred in a young woman supposed to be in labor.* She denied pregnancy, but violent bearing-down pains, with short intervals, were pre- * Hewitt, 4th Edition, Vol. II, p. 448. CASE TAKING. 63 sent; the abdomen was enlarged to the size of a nine months' pregnancy. Catheterization removed an incredible amount of urine from the bladder, and the diagnosis became plain. I have seen the bladder quite as much distended, but the patient was moribund from puerperal septicemia.* Both of these cases show most emphatically the danger of relying solely upon sub- jective symptoms. Intermittent pains resulting from tumors of the uterus are usually of a bearing-down character, and have already been described. Persistent pain in the hypogastric region has its origin in cysti- tis and is accompanied with more or less dysuria. The pain of cystitis is subject to exacerbations and remissions, but is, never- theless, persistent. The degree of suffering is influenced by the extent and severity of the inflammation. Cystitis gives rise to variable quantities of ropy pus in the urine. Fibroma and Carcinoma Uteri and Flexions, may give rise to persistent pain. The pain of cancer, when persistent, is peculiar, although not pathognomonic. It does not occur until the peri- uterine tissues are involved, when it is of a dull, aching, sickening character, and may be burning or darting, seemingly transfixing the whole pelvis (Rigby). Pains of this character, particularly if associated with a suspicious discharge and cachexia, demand of the examiner an immediate exploration of the parts. But it should not be forgotten that cancer may progress even to ulcera- tion through and into the bladder with little or no pain, and abso- lutely no perceptible constitutional disturbance. Such a case presented herself at my clinic during the winter of 1888. The patient sought relief because of the discharge of urine through an ulcerated opening into the bladder. An examination revealed a broken-down scirrhus of the cervix, involving the base of the bladder. There had been no pain, and the features were those of a most vigorous woman. The pain of inflammation as a subjective symptom is not pathognomonic. It is acute in character, is usually traceable to some definite cause, and constitutional symptoms are present; * Transactions of the American Institute of Homeopathy, 1889, p. 676. 64 A TEXT-BOOK OF GYNECOLOGY. the pulse is increased, the temperature elevated, and there is more or less tenderness of the affected parts. Chilliness or a decided chill usually ushers in such an attack. The severity of the suffering varies according to the extent of tissue involved and the constitutional impression made. Pain with symptoms of shock, and collapse, is always of serious import. It is suggestive of rupture or perforation of some one of the pelvic viscera, with an escape of their contents or of blood into the peritoneal cavity. Such an accident follows a ruptured ectopic pregnancy cyst-according to Lawson Tait this is the chief if not the only cause of hematocele-when the severity of the shock depends upon the direction of the rupture: if between the folds of the broad ligament, it is not necessarily very great; if, on the contrary, it occurs in the free peritoneal cavity, there is nothing to limit the quantity of blood discharged and the symptoms at once become profound if death does not speedily ensue. The ordinary symptoms of pregnancy may have pre- ceded such an attack, but unfortunately the history often affords no clue as to its nature. Hematocele due to causes other than ectopic pregnancy is more apt to occur during or near a men- strual period. In all forms of hematocele the presence of the effused blood frequently excites much tenesmus and bearing down. Rupture of an ovarian cyst and of a gravid uterus give rise to shock. The symptoms of a ruptured uterus do not differ from those of a ruptured ectopic pregnancy cyst, except that the cause is obvious, and if the accident happens during labor the child will recede from the examining finger. The character of the contents of an ovarian cyst will determine the symptoms after rupture. If bland and unirritating the symptoms are not marked; if purulent, fatal peritonitis may quickly follow unless the abdomen is speedily opened. The symptoms of shock, whatever the cause, are much the same. It is characterized by prostration, fainting, feeble or nearly imperceptible pulse, great paleness, pinched features, cold, clammy perspiration, nausea and vomiting. Whenever the foregoing symptoms present they demand of the physician immediate and unremitting attention. CASE TAKING. 65 Sacral and Coccygeal Region.—Pain in this region may be due to actual disease of the bones or periosteum, to a displaced uterus, to pressure exerted by inflammatory exudates, or it may be purely reflex. A persistent pain in the sacral region always gives rise to a suspicion of retro-displacement of the uterus. Involvement of the retro-uterine cellular tissue will excite an obstinate sacral pain. I have often found it present when the utero-sacral ligaments were contracted by cellulitis. Mundé observes that adenitis and angioleucitis-inflammation of the lymphatic glands and vessels of the pelvic cellular tissue-are many times the cause of sacral pain. When the coccyx is implicated this bone should be carefully examined for the evidences of injury or necrosis. Often the cause is entirely obscure, and for the want of a better explanation the symptoms are relegated to the domain of “neuralgia.” Vulvar Region.-Pain in these parts usually has its origin in some form of specific or non-specific inflammation in the region of the labia or the introitus vaginæ. Disease of the Bartholinian glands, abscess and specific or malignant ulceration may like- wise excite vulvar pain. When vulvar pain is complained of an inspection of the parts should be made before indagation is practised. Lower Extremities.-Pressure upon the sacral plexus of nerves is the usual intra-pelvic cause of pain in the lower limbs. Tumors, inflammatory deposits, and retro-displacements exert such pressure, when the pain is confined to the posterior surface of the limbs. Painful cramps in the calves of the legs, like those occurring during labor, may result from pressure of any kind. When the pain is confined to the anterior part of the thigh another set of nerves is involved, and pressure is not the cause, unless it is exerted by a psoas abscess, or by an anteflexed uterus. Usually pain in this region is due to anteflexion; in other instances the pain may be purely reflex. From whatever cause, it may manifest itself in any portion of the limb to which the involved nerve or nerves are distributed. I have seen a pain limited to a very small portion of the anterior tibial region, which had persisted for three years, disappear immediately upon repairing a lacerated cervix. Irritable carunculæ, lesions of the rectum, 5 66 A TEXT-BOOK OF GYNECOLOGY. bladder, and urethra, may give rise to pain in the lower extremi- ties and even to paraplegia (Thomas). General. The general symptoms of uterine disease are in- numerable. In the chapters devoted to the Hystero-Neuroses they are treated of in detail. It is sufficient at this time to observe that any and every part of the body may be the seat of disturbance whose origin is within the pelvis. This may be the result of pain directly reflected, or secondary to depraved nutri- tion, which follows in the train of disordered digestion and malassimilation. The stomach, the liver, and the intestinal canal are frequently affected in a reflex way, giving rise to dyspepsia, cardialgia, nausea, vomiting, anorexia, jaundice, diarrhoea, con- stipation, etc. Persistent pain in the occiput or vertex, worse during menstruation, is almost pathognomonic of uterine disease. So also is pain in the left infra-mammary region. Spinal irritation is a part of the general "neurasthenia" which supervenes as the nutrition suffers. In short, the entire system is often profoundly and permanently impressed by utero-ovarian lesions. AS REGARDS FUNCTION. Menstruation.-Dysmenorrhea is the term by which painful menstruation is designated. Few women are absolutely free from pain during menstruation. By observing the character and the circumstances under which it appears, it is possible to form a very intelligent idea of the cause of the suffering. Pains radiat- ing from the uterine region, occurring in paroxysms, and terminat- ing with a more or less profuse discharge of blood from the vagina, suggest an obstruction to the exit of blood. Pain in the ovarian region for two or three days preceding the onset of the flow, and usually relieved by it, would direct attention to the cor- responding ovary as the probable seat of mischief. If the flow is uninterrupted, the pain sharp and fixed, or comes and goes in quick succession, and the patient is of a neuralgic or gouty dia- thesis, the cause is probably systemic and there will be an absence of local lesions. If it appears suddenly during menstruation, fol- lowed by suppression and constitutional disturbance, acute con- gestion or actual inflammation is the usual cause. Or if the pains resemble those of labor and occur simultaneously with the CASE TAKING. 67 flow, ceasing upon the expulsion of a clot whose nucleus is a piece of membrane, the symptoms are probably due to mem- branous dysmenorrhea. Defecation.-From the standpoint of both physiology and pathology the female pelvic organs are a unit, and the gynecolo- gist can no longer ignore the influence which the rectum and the bladder exert upon the generative organs. Painful defecation may be the only symptom of which the patient complains. It may be due to one or more of the following causes: Cancer, stricture, fissure, hemorrhoids, polypi, prolapsus of the ovary, pressure exerted by a sensitive fundus or cervix, pelvic exuda- tion, fistula, rectocele, and proctitis. From the character of the pain alone we can only surmise the nature of the lesion. accurate diagnostic purposes a local examination is imperative. Micturition.-Only the factors concerned in painful micturi- tion are to be mentioned at this time. These are: Inflammatory diseases of the bladder and urethra, malignant disease of the bladder, vascular tumors and eversion of the mucous membrane of the urethra, abnormal positions of the uterus, vesical calculi, disease of the ostium vaginæ, and abnormal conditions of the urine. For Inflammation of the bladder and urethra may be either acute or chronic. If limited to the bladder pain is present more or less constantly, and especially during micturition. The inflammation in both instances may be due to a number of causes. In the rare instances of idiopathic malignant disease of the bladder the pain is worse immediately following micturition. Turbidity of urine, with or without blood, is a symptom of carci- noma of the bladder. In hematuria the source of the blood can only be determined by a careful, and perhaps, repeated examina- tion of the urine. The endoscope, in experienced hands, is very useful in diagnosing vesical lesions. Vascular tumors of the urethra, unlike urethritis, cause a per- sistence of the pain during and after micturition which lasts for an indefinite length of time. Eversion of the mucous membrane, in both young girls and married women, may excite dysuria. Benecke has reported three cases. of prolapse of the urethral mucous membrane in young girls. I have seen, in an elderly 68 A TEXT-BOOK OF GYNECOLOGY. woman, a similar prolapse as large as a pigeon's egg, which was the cause of very painful micturition. Abnormal positions of the uterus are more apt to cause difficult than painful micturition. However, I have often seen both difficult and painful micturition caused by retraction of the utero-sacral ligaments, drawing the cervix and the base of the bladder backward. The pain resulting from vesical calculus is worse immediately after the bladder is emptied, and is caused by the contact of the bladder walls with the stone. Calculi almost invariably excite, sooner or later, cystitis. Any disease of the ostium vaginæ causing it to be inflamed or ulcerated, will excite more or less pain after micturition. Such are the various forms of inflammation, and specific and malignant forms of ulceration. Excoriation of the vaginal out- let is not infrequently due to abnormalities of the urine. Coition.-Painful sexual intercourse, or dyspareunia, may be. the one and only symptom for which the gynecologist is con- sulted. The causes are many and may be enumerated as fol- lows: Pelvic congestion from any cause; inflammation of any of the generative or pelvic organs; ovarian tenderness or pro- lapse; irritable caruncles; fissure or ulcers of the vulva, urethra, or anus; neuromata of the vulva; coccygodynia; simple hyper- esthesia without evident lesion; and atresia or stenosis of the vulva or vagina. AS REGARDS POSTURE. Erect. The bearing-down pains, pains in the lower extremi- ties, and those caused by inflammation, are aggravated by the erect posture, and especially by walking. The distress incident to relaxation of the pelvic floor with uterine and vaginal dis- placements is often felt only in this posture. Sitting. If the female perineum is pressed upon in the direc- tion of the axis of the pelvic brim, there will be more or less bulging of the hypogastrium. (Duncan.) Although the peri- neum is protected by the tuberosities of the ischia, a certain amount of pressure is exerted upon it in the sitting posture, which pressure is communicated to the deeper parts. The bowels and the pelvic organs are, therefore, in a measure squeezed (( CASE TAKING. 69 while the woman is sitting, and, if inflamed or tender from any cause, pain is liable to result. A prolapsed ovary may be im- pinged upon in no other posture. Disease or displacement of the coccyx and of the rectum may make sitting painful or im- possible. When coccygodynia is present the pain is excruciat- ing during defecation and while the patient is rising from the chair. Reclining. There are few if any gynecological diseases made worse by the reclining posture. When the spinal cord is secondarily involved, either in a reflex way or from nutritive changes, Hammond gives a diagnostic point worth noting. It is this: If the pain in the back be due to anemia of the cord it is made better by lying upon the back, when the blood will gravitate to the cord and its membranes, thus temporarily over- coming the anemia; if, on the contrary, the pain be due to con- gestion it will be aggravated in the dorsal posture. The therapeutist will many times be able to base his pre- scription upon the numerous and varied expressions of pain which has its origin within the pelvis. To him it will be “sig- nificant" both from a diagnostic and a therapeutic standpoint. Nevertheless, the careful diagnostician and therapeutist will weigh carefully the value of purely subjective testimony. Pain, as a symptom, will prove most serviceable to him who holds path- ology and drug pathogenesy to be inseparable. CHAPTER IV. THE SIGNIFICANCE OF DISCHARGES IN DIAGNOSIS. In a physiological state the mucous membrane of the genital tract, extending from the ostium vagina to the fimbriated extre- mity of the Fallopian tubes, secretes only enough fluid to lubri- cate its opposed surfaces. Over the inner surface of the labia, the clitoris and the nym- phæ are sebaceous follicles which secrete sebaceous matter con- taining butyric acid. The vulvo-vaginal glands, and numerous muciparous follicles, are located at the sides of the vaginal aper- ture, from which is poured a viscid mucus, which is increased during the sexual orgasm. The secretion from the vaginal mucous membrane is transparent and, under the microscope, shows variable quantities of broken-down epithelium. The arbor vite of the cervix contain many glands of the racemose type, dilated at their extremities and extending deeply into the connective tissue. (Ruge and Veit.) These are exceed- ingly numerous and from them is poured a tenacious, viscid secretion of an alkaline reaction. When in a state of activity the quantity may be enormous. Microscopically, it contains epithelium of the columnar variety and mucous corpuscles. The cervical discharge rarely preserves its characteristic appearance when it escapes from the vagina; after the secretion from the cervix and the vagina commingle, the effect is a white, soapy or creamy fluid. PATHOLOGY. No perfect division based upon the physical character of the discharges can be made, for rarely is the discharge, as it escapes from the vagina, derived from one source. The following classi- fication is, therefore, made solely for the convenience of study. 70 THE SIGNIFICANCE OF DISCHARGES IN DIAGNOSIS. 71 I. Mucous; 2. Purulent; 3. Watery; 4. Sanious; 5. Offensive; 6. Hemorrhagic. The character, source, and significance of these several dis- charges are contrasted in the succeeding table. DISCHARGES. Character and Properties. Mucous.-Contains oil globules and epithelial débris. If from the cervix, may Source. Cervical canal. Uterine cavity. resemble unboiled white of (Rare.) egg. If from the vagina, curdy looking and of acid reaction. Thick, creamy, and of SIGNIFICANCE. Exaggeration of normal secretion after menstruation and during preg- Fallopian tubes. nancy. Early stage of inflammation, either specific or non-specific. Ane- mia, chlorosis, Bright's disease, etc. When plugging the cervical canal it may be the cause of sterility. External surface acid reaction. Frequently and lips of cervix. white or yellowish white and at times almost membranous in character. Epithelial cells and oil globules are also present. Acid mucus. Occasionally Vagina. Cervical metritis and endometritis. Cystic degeneration. parasites and fungi (Tricho- monas vaginalis; Leptothrix buccalis). Purulent.-May be thick Fallopian tubes. or thin, profuse or scanty, (Rare.) fetid or odorless, and some- Uterine cavity. times tinged with blood. Same as above. May be Cervix. sanious or, if gonorrheal, thick and yellow. Vagina. Vulva. Same as above. Quantity Suppurating cyst. Pelvic abscess. great. Inflammation, either specific or non-specific. Aphthous ulceration. Pyosalpinx or chronic endome- tritis, the result of either specific or non-specific inflammation. If spe- cific, gonococci may be present. Suppuration of retained membranes after abortion. Carcinoma. When the quantity is considerable and non- continuous, probably due to partial cervical obstruction. Carcinoma. Chronic inflammation -specific or non-specific. Syphilitic ulceration. or Opening either into uterus vagina. History of tumor or pelvic inflammation. Symptoms abate after discharge of pus. 72 A TEXT-BOOK OF GYNECOLOGY. CHARACTER AND PROPERTIES. DISCHARGES.-Continued. Source. Watery.-Quantity vari- Uterus. able, may be great. Hyda- tidiform bodies often expelled with fluid. Dirty yellow or pale yel- Cervix. low, clear, watery, or mixed with blood. Quantity may be very great. Ovarian fluid. Abdomen. Urinous odor. Bladder. Sanious.-Leucorrhea apt to be profuse. Uterine cavity. Discharges modified by Cervix. character of lesion. Blood-tinged pus. Quan- Pelvis. tity usually great. quantity. Frequently sanious. Offensive. — Variable in Uterine cavity. Cervix. Vagina. Hemorrhagic.-Bright or dark, thin, thick, or clotted. Contains débris of uterine tissue, fatty and oil particles mucous corpuscles, or the products of suppuration and inflammation. Variable; usually much degenerated. Vulva. Uterine cavity. General. SIGNIFICANCE. Pregnancy.-From the amnion. Hydatidiform mole-rapid enlarge- ment of uterus with absence of the usual symptoms of pregnancy. Tubercle.-Very rare; secondary to general tuberculosis. Polypi (v. Note 2). Cauliflower excrescence. (Ramsbotham.) Contents of ovarian cyst escaping into Fallopian tube or uterus.—— History of abdominal tumor with sudden diminution. (Rare.) Vesico-vaginal or vesico-uterine fistula. Frequently involuntary while laughing or coughing. Associated with menorrhagia, po- lypi, and fibroma. Discharge al- ternates with actual hemorrhage. Fungoid or granular endometritis. Abrasion or ulceration. Hematocele.-Previous history of shock, collapse, and inflammation. Retained products of conception.— History of pregnancy. Sarcoma. Not offensive until necrosis of tissue occurs; peculiar discharge resembling washings of fresh meat. True carcinoma.-Not offensive until necrosis of tissue occurs. (Char- acteristic odor of malignancy.) Retained menstrual blood.-Want of cleanliness. Excessive menstruation due to uterine disease (endometritis, fibro- ma, etc.). Displacement. Meno- pause.-Age. Tumors.-Quantity does not depend upon size. (Usu- ally metrorrhagia and menorrhagia.) Hematocele.-Shock and collapse. Constitutional.-Purpura, tuber- culosis, Bright's disease, syphilis, plethora, malaria, exanthemata, dis- orders of the heart, lungs, and liver. ((a) Centric.-Emotional. (b) Reflex.—Ovarian, vesical, rectal, and mammary irritation. NERVOUS. THE SIGNIFICANCE OF DISCHARGES IN DIAGNOSIS. 73 CHARACTER AND PROPERTIES. Hemorrhagic.-When due to constitutional causes-ve- nous. When due to trauma- tism-arterial. DISCHARGES.-Continued. Source. Cervix. Vagina. Vulva. Venous and arterial, Rectum. SIGNIFICANCE. Constitutional.-Same as above. Traumatism.-Surgical, accidental, varicosis, thrombosis, vascular ex- crescences. Malignancy.-Pain, leucorrhea, cachexia. Congestion, polypi, fissure, malig- nant and non-malignant ulceration, traumatism, hemorrhoids. DIAGNOSIS OF BODIES EXPELLED FROM THE VAGINA. CHARACTER. Early ovum. Source. Uterus. Vesicular moles.-(Cystic Uterus. degeneration of the chori- onic villi.) Cysts simple. True Hydatids.-Cysts complex, i.e., closed sacs, one within another. Abdomen. Uterus. Membranous bodies. Dys- Uterus. menorrheal membrane. Vaginal Membrane.-En- Vagina. tire mucous lining may be cast off. (Rare.) Thin, trans- lucent flakes. Kidney. Mucous membrane of Bladder. bladder. Mucous membrane of kidney pelvis. SIGNIFICANCE AND DIAGNOSIS. If any portion of the fetus be found the diagnosis is conclusive. Examine carefully for: (a) decidua materna; (b) decidua reflexa; (c) chorionic villi; (d) umbilical cord. Always a product of conception.— Early death of fetus, which dis- solves and disappears; villi of chorion becomes distended with fluid. Symp- toms (v. "watery discharges" and Fig. 20). Not a product of conception.— Microscope shows echinococci * heads and booklets. (Very Rare.) Not a product of conception.- Rough and slightly flocculent exter- nally, smooth internally. May be cast off en masse or in pieces. No evidence of chorionic villi. Repeti- tion each month. Pathology obscure. Inflammation and sloughing. Mi- croscope reveals characteristic squa- mous and cylindrical epithelium. Cystitis and Pyelitis.-The shape of the membranes, the history of bladder or renal trouble and the composition of the urine must be studied. * Vide London Obstet. Trans., vol. xii, p. 237. 74 A TEXT-BOOK OF GYNECOLOGY. DIAGNOSIS OF BODIES EXPELLED FROM VAGINA.—Continued. CHARACTER. Source. Fleshy Moles.-(Ovum Uterus. with blood effused between the membranes, which be- comes organized.) Placenta.-(May remain for an indefinite time with- out decomposition.) Uterus. Fibrous polypi. Fibroid Cervix. tumors. Cancerous masses. Uterus. Blood Polypi-Surface may be dense, grayish, or Uterus. Vagina. fibrinous looking. If from the vagina, large. Significance AND DIAGNOSIS. Always a product of conception.— Examine for chorionic villi. History of pregnancy. Expulsion usually preceded by an offensive discharge. Early pla- centa about the size of a pigeon's egg. Examine for umbilical cord, chorionic villi, etc. A positive diag. nosis may be impossible. Absence of all evidences of con- ception. Microscope will reveal true character. History of menorrhagia. Fibroid tumors may become calci- fied. Occurs more often in connection with abortion. Due to some obstruc- tion either in the uterus or the vagina. When recent, easily broken down. Microscope will show blood-cor- puscles. The Microscope. This instrument is invaluable in the exam- ination of suspicious discharges, curettings, adventitious growths, etc. Its application is often the only reliable test in the early stages of malignancy. Since the discovery of the gonococcus, the microscope is relied upon more than ever as a means of diagnosis. While the matter is yet sub judice the weight of evidence tends to the belief that the presence of gonococci in pus is pathognomonic of gonorrhea, though failure to find them does not necessarily signify its non-gonorrheal origin. Bearing upon this question the series of observations made by Aubert are the most recent and valuable. The importance of this sub- ject from a medico-legal standpoint is very great. Aubert's method of examination is as follows :*— A drop of pus is placed upon a glass slide, spread very thinly with another slide, and allowed to dry. This is then stained with * Lyon Médical, February, 1889. THE SIGNIFICANCE OF DISCHARGES IN DIAGNOSIS. 75 an alcoholic solution of methyl violet diluted with water. Ex- posing the specimen for a few seconds, it is then washed with water, left a little moist, covered with a thin cover glass, and placed under the microscope. The gonococci appear in stained, FIG. 20. VESICULAR OR HYDATIDIFORM MOLE. Museum R. C. S. (Photographed by Author.) scattered or grouped granules, either within or outside the pus cells.* *NOTE 1.-Aubert summarizes his conclusions as follows:- 1. A search for the gonococcus should always be made when an accurate diagnosis is important, and when found should be considered characteristic of blennorrhagic (gonorrheal) pus. 2. The microorganisms must be grouped in the protoplasm of the pus-cells and 76 A TEXT-BOOK OF GYNECOLOGY. CONCLUSIONS. 1. An abnormal discharge or hemorrhage from the genital tract is but a symptom of some abnormal condition, either local or general. It is the first duty of the physician to deter- mine the cause of this symptom. 2. When a continuous or exaggerated discharge of blood from the uterus is not controlled by ordinary measures, a careful examination, per vaginam, becomes imperative. Failing to dis- cover the cause by this method, dilatation and exploration of the uterus should always be made. 3. If any symptoms of malignancy of the fundus exist, the uterus should be curetted and the products examined by an experienced microscopist; or if the cervix is involved, and proper treatment does not affect the induration, a section should be exposed for microscopic examination. around the nuclei in order to be characteristic. While a single well-defined cell may be sufficient, full dependence cannot be placed upon cocci, scattered or in groups, outside the pus-cells. 3. Dependence should not be placed upon a search for gonococci unless the pus is obtained directly from the secreting surface and immediately spread out and dried. The staining and examination can then be made at leisure. 4. It is impossible, at the present time, to determine positively as to the presence or absence of gonococci from the examination of dried purulent discharge on linen, because of the disintegration of the pus corpuscles, and the want of characteristic grouping of the microbes. 5. Too much confidence should not, at present, be placed in the cultures made from linen stained for some time with gonorrheal pus. 6. The numerous sources of accidental contagion should be remembered: there- fore, while the presence of gonorrhea may be determined in a given case, its source, particularly in little girls, should be made a matter of independent proof at the judicial inquiry. NOTE 2.—Case.—"Sarah W, October 27th, was admitted as an out-patient of the Lying-in Hospital Has had eleven children. Was confined with last child one year ago. The labor was a favorable one, but there was some adhesion of the placenta, which required the introduction of the hand for its removal. She has had constantly some discharge ever since her confinement. Until the last month the dis- charge has been chiefly of a watery character, and so abundant as to soak four or five napkins each day, but scarcely to color them. On making an examination per vaginam, I found a tumor the size of a small hen's egg, insensible to the touch, occupying the upper part of the vagina, the os uteri, and apparently attached to the inner surface of the cervix uteri.”—“ Obstetrical Transactions,” Vol. I, p. 112. * * * CHAPTER V. PHYSICAL EXAMINATION. INSTRUMENTS AND APPLIANCES NECESSARY FOR DIAG- I. Table or chair. NOSIS. 2. Specula: (a) Vaginal, (b) rectal, (c) urethral. 3. Dressing forceps. 4. Uterine sound and probe. 5. Uterine dilators. 6. Tenacula, volsella forceps, and depressor. 7. Curette. 8. Aspirator. 9. Stethoscope. 10. Tape measure and pelvimeters. II. Thermometer. 12. Microscope. 13. Inhaler for anesthesia. Table or Chair.-For ordinary office work I much prefer a gynecological chair to a table. There are so many good chairs on the market as to make it necessary for the purchaser to put himself out in order to find a poor one. Personally, I prefer the Harvard. It possesses nearly all of the requisite good points and but few that are bad. The mechanism, while simple and durable, is such as to permit of any desired position of the patient. The gynecological positions are shown in Fig. 21 and require no extended description. The Depew chair, manufac- tured by R. Boericke & Co., likewise possesses especial merit. Specula. Of the innumerable vaginal specula there are but three general types now in use: (a) expanding, which are either bi-, tri-, or quadri-valvular; (6) uni-valvular, or Sims's; and (c) the cylindrical or tubular. In America the bi- or tri-valve specula are in more general 77 78 A TEXT-BOOK OF GYNECOLOGY. use by the non-specialist. The specialist, with an assistant at his command, will ever prefer the Sims or some of its modifications. The cylindrical is still very popular with many practitioners, par- ticularly in England. FIG. 21. B-Dorsal position. A-Full length reclining position. Smit C-For elevating the hips. D-Sims position. THE HARVARD CHAIR. In selecting a bi- or tri-valve speculum both shape and simplicity should be considered. The blades should not be too FIG. 22. G. TIEMANN-CC THOMAS'S-CUSCO'S SPECULUM. long, nor the circumference great enough to cause pain. I have had in constant use for ten years a Cusco's of ordinary size (Fig. 22) and a Nott's Virgin (Fig. 23). Each possesses both merit { FIG. 23. G.TIEMANN-CO NOTT'S VIRGIN SPECULUM. A A G TILMANN FIG. 24. BREWER'S SPECULUM. FIG. 25. BREWER'S SPECULUM USED AS A SIMS. 79 80 A TEXT-BOOK OF GYNECOLOGY. and demerit, as do the Brewer (Fig. 24), the Graves and the Goodell (Fig. 26). Both the Brewer and the Graves (Fig. 25) can be converted into a uni-valvular speculum-a poor substi- tute for the original Sims. FIG. 26. GOODELL'S SPECULUM. Fig. 27 represents my own instrument. The advantages claimed for it are the following:- I. It is so constructed as to pass with ease into the posterior vaginal fornix without causing pain at the ostium vaginæ, which so often results from efforts to pass the tip of an ordinary bi- C a FIG. 27. GTIEMANN & CO. valve instrument when the uterus is retroposed, par- ticularly in virgins. 2. Its peculiar shape makes it perfectly self-re- taining. only 3. The joints are at b, and these can be un- THE AUTHOR'S SPECULum. locked in an in- stant, making it aseptic and convenient to carry. The blades are fixed by the ratchet, c. 4. By means of the fixed handles the blades are under the perfect control of the operator, and can be depressed or elevated so as easily to expose the cervix. There being no set-screw, the separation and closing of the blades requires but one hand. There are many modifications of the Sims speculum, though + PHYSICAL EXAMINATION. 81 but few of these are an improvement upon the original design. (Fig. 28.) The most important is the expansion, made by Mundé, of one blade at its upper edge into a flange to prevent the buttock from obscuring the view when no assistant can FIG. 28. G.TIEMANN -CO. SIMS'S SPECULUM. be had. (Fig 29.) Porter's modification is highly spoken of by those who have used it. The blades of the average Sims speculum are too long and, particularly for operating purposes, FIG. 29. G.TIEMANN & CO. MUNDE'S MODIFICATION OF SIMS'S SPECULUM. too narrow. A virgin size makes an excellent rectal speculum as well. Many self-retaining univalvular specula have been invented, the most useful being Emmet's (Fig. 30) and Cleveland's (Fig. 31), the object being to make an assistant unnecessary. They 6 82 A TEXT-BOOK OF GYNECOLOGY, have never become popular and, probably, never will. With an assistant there is no vaginal speculum equal to the Sims; with- FIG. 30. 3. TIEMANN-Cu. EMMET'S SELF-RETAINING SIMS'S SPECULUM. FIG. 31. G TIEMANN & CO. Cleveland's SPECULUM. FIG. 32. GTIEMANN FO OTIEMANN COF SIMON'S SPECULA. out one some form of expanding instrument is infinitely more convenient and useful for diagnostic purposes. Simon's specula (Fig. 32) are uni-valvular, like the Sims, but PHYSICAL EXAMINATION. 83 are used with the patient in the dorsal posture. The upper blade has been made hollow, to which is attached a stop-cock so that it can be connected with an irrigator (Frisch's modification). Latterly I have been using Frisch's instrument for nearly all operations within the vagina. The cylindrical specula come in sets of five each (Fig. 33), and are made of wood, metal, glass, gutta-percha, hard rubber, or FIG. 33. 6 TIEMANN&CO FERGUSON'S SPECULUM, TUBULAR. horn. They vary in diameter from one-half to two inches, and in length from four to six inches. One longer than five inches is impracticable. I cannot conceive the usefulness of this instru- ment as compared with a good bi-valve. As already intimated, a small Sims's, or rather two Sims's, specula make a very good rectal speculum, particularly after divul- FIG. 34. G.TIEMANN -CO BI-VALVE RECTAL SPECULUM. sion and when the patient is under anesthesia. For examination at other times an expanding instrument is more useful. Very good ones are shown in Figs. 34 and 35. Pratt's bi-valve is also an admirable instrument, especially for operative purposes. The use of urethral specula is necessarily more or less unsatis- factory. Expanding instruments of any kind will expose the outer third of the canal without any difficulty. One of the most 84 A TEXT-BOOK OF GYNECOLOGY. popular specula constructed upon this principle is Skene's (Fig. 36), though the tips of dressing forceps, or, better still, an expand- FIG. 35. G.TIEMANN & CO. WILLIAMS'S RECTAL SPECULUM. ing ear speculum, will do very well. For examining the deeper portion of the canal or the walls of the bladder an endoscope FIG. 36. G.TIEMANN&CO. CATURN SKENE'S URETHRAL SPECULUM. or a cystoscope is necessary. Skene's endoscope (Fig. 37) and the cystoscope of Nitze & Leiter (Fig. 38) are the best. To use FIG. 37. Fig 1 GTIEMANN TIEMANI a Fig 2. Fig 3 SKENE'S URETHRAL ENDOSCOPE. either of these two instruments with success much practice is required. PHYSICAL EXAMINATION. 85 At least two Uterine Sounds-one stiff and one flexible— should be in the possession of every physician who is called upon to make gynecological examinations. Of the stiff sounds, Simpson's is the most popular (Fig. 39). Although sufficiently FIG. 38. GTIEMANN & CO. CYSTOSCOPE OF NITZE & LEITER. stiff to retain its shape and curve despite any ordinary force, it is flexible enough to be moulded by the finger. It is graduated in quarter inches and inches, and at a distance of two and a half inches from the tip there is a small knob indicating the normal depth of the uterine cavity. FIG. 39. GEO TIEMANN&Co. munu SIMPSON'S UTERINE SOUnd. Of the flexible sounds or probes, Sims's (Fig. 40) is typical. Very flexible silver probes, bending at the slightest impediment, are frequently required in penetrating the uterine cavity when its canal is constricted or impinged upon by intra-uterine FIG. 40. G TIEMANN=CO SIMS'S FLEXIBLE Probe. growths. Elastic whalebone or hard rubber probes of similar size are often necessary. Tenacula are made in different shapes, the best for all pur- poses being that represented in Fig. 41. The handle, for aseptic 86 A TEXT-BOOK OF GYNECOLOGY. reasons, should be of metal. Volsella Forceps may be used instead of the tenaculum for the purpose of fixing the cervix. during examinations and operations. FIG. 41. G.TIEMANN &CO. LONG ANGULAR TENACULUM. Nott's Depressor (Fig. 42) is used to push the anterior vaginal wall forward in using the Sims speculum. FIG. 42. 6.TIEMANN.CO. NOTT'S DEPRESSOR. Hank's hard rubber Uterine Dilators are inexpensive and good (Fig. 43). They come in sets of six each, thus giving FIG. 43. G.TIEMANN & CO B C HANK'S HARD RUBBER UTERINE DILATORS. twelve sizes. For rapid dilatation a steel instrument is necessary (Fig. 44). FIG. 44. G.TIEMANN & CO. WYLIE'S UTERINE DILATOR. The Curette is used in diagnosis to remove tissue for micro- scopical examination, therefore a sharp instrument (Simon's) is PHYSICAL EXAMINATION. 87 ordinarily preferable (Fig. 45). When the sharp curette is deemed unsafe, Thomas's dull wire instrument may be used instead (Fig. 46). A large Hypodermic Syringe with a long needle can be advantageously utilized as an aspirator when only enough fluid FIG. 45. G. TIEMANN-CO.N.Y. SIMON'S SPOON CURETTE. is desired to ascertain its character. The most serviceable aspirator for all purposes is Dieulafoy's. Dressing Forceps are indispensable to the gynecologist. I prefer a long, straight instrument made upon the principle of the ordinary dissecting forceps. The late Professor Dunster devised FIG. 46. THOMAS'S DULL WIRE Curette. such an instrument. Bozeman's dressing forceps is also a very useful instrument and can be used as an applicator as well. (Fig. 47.) The Stethoscope is used in differentiating sounds within the abdominal cavity. The dimensions of the external surface of the abdomen and 88 A TEXT-BOOK OF GYNECOLOGY. the size of the pelvis are determined by the Tape-Measure and the Pelvimeters. The use made of the Microscope in diagnosis is discussed in Chapter IV. A good Clinical Thermometer is a sine qua non in gyneco- FIG. 47. G.TIEMANN & CO. BOZEMAN'S DRESSING FORCEPS. logical work. Only by its use is it possible to determine actual systemic disturbances, thus differentiating between pain due to purely functional trouble and that resulting from pus or inflam- mation. Anesthesia.-An examination without anesthesia is rendered unsatisfactory or impossible under the following circumstances: FIG. 48. FLAM ANA 2⠀ JUNKER'S INHaler. (a) When the abdominal walls are unusually tense or tender; (b) when phantom pregnancy is suspected; and (c) in young girls when the parts are exceedingly tender. When used for diagnostic purposes chloroform is the preferable anesthetic. PHYSICAL EXAMINATION. 89 POSITIONS FOR EXAMINATION. (a) level-dorsal, I. Dorsal recumbent (b) gluteo-dorsal, 2. Lateral. (c) lithotomy-dorsal. 3. Latero-abdominal, or Sims's. 4. Abdominal. 5. Genu-pectoral. 6. Erect. It may be necessary in a given case to utilize more than one, or, indeed, all of these positions. In America the dorsal posture is usually the first resorted to for inspection and for digital or ordinary specular examination. If the Sims speculum is used, the patient is then placed in the latero-abdominal position. In England the lateral or latero-abdominal is the usual one for both digital and specular exploration. The patient's person should be protected as much as possible with a sheet possessing an opening a little below its middle, through which the abdomen can be exposed and the hand or instruments passed. Gentleness and tact are requisites without which no physician can become a successful gynecologist. 1. Dorsal Recumbent. (a) Level-Dorsal.-In this position the pelvic viscera are at rest and the diaphragm exercises a minimum of displacing power upon them. The knees are flexed so that the thighs are almost at right angles with the abdomen; the head, shoulders, sacrum, and soles of feet are on nearly the same plane. digital and bimanual examination it is the best position. In (b) Gluteo-Dorsal.-The thighs are acutely flexed upon the abdomen with the knees touching the thorax and separated as widely as possible. This position is utilized when the vagina is unusually long or when the perineum or abdominal walls are exceedingly rigid. In it the symphysis is greatly elevated while the sacral promontory is correspondingly depressed, so that it is more easily reached with the finger. The vagina is directed almost perpendicularly downward and, per rectum, the posterior 90 A TEXT-BOOK OF GYNECOLOGY. surface of the uterus is accessible. Palpation is, in this position, facilitated because of the complete relaxation of the abdominal walls and the diminished intra-abdominal pressure. (c) Lithotomy-Dorsal.-This position is much more com- fortable for the patient than the gluteo-dorsal. The shoulder and thorax are so elevated that the trunk rests upon an inclined plane FIG. 49. Krakhyourdel LATERO-ABDOMINAL, OR SIMS'S POSTURE. (Skene.) at an angle of about 20°, the feet remaining upon a horizontal plane with the sacrum. Intra-abdominal pressure is increased by the elevation of the thorax, hence this position is less adapted than the gluteo-dorsal for bimanual examination. 2. Lateral. The patient lies upon either side, preferably the left, her head PHYSICAL EXAMINATION. 91 supported merely by a pillow. The shoulders and hips are perpendicular to a horizontal plane, the hips down to the edge of the table and the thighs flexed at right angles to the body. The lateral and posterior portions of the pelvis are more accessible to the examining finger than in the dorsal positions. Thus a slight perimetric exudation, or a dislocated ovary which escaped observation while on the back, may be detected. It is the usual position for explorations of the rectum. However, nearly, if not quite, as much information can be gained with the patient either upon her back or in the latero-abdominal position. 3. Latero-abdominal, or Sims's. While other forms of specula can be introduced in this posi- tion, it is chiefly used for the introduction of the uni-valvular or Sims's. In it the abdominal viscera gravitate forward and down- ward away from the pelvic cavity. By admitting air into the vagina and separating the labia the whole vaginal tract is exposed. The correct position, together with the proper method of holding the speculum, is beautifully shown in Fig. 49. The patient lies upon her side, usually the left, her head supported by a low pillow, and on a perfectly flat, hard table. The left arm is thrown out behind and hangs over the edge of the table, while the left shoulder, the lower half of the chest, and the left hip touch the table. The thighs and knees are flexed at right angles to the body, the right knee slightly overlapping the left. A lateral or downward inclination of the table greatly facilitates the examination. The position is unrivaled for ocular examina- tion, and is imperative in many operative procedures on the cervix and vagina. 4. Abdominal. In this position the abdomen and thorax rest upon the examining couch. To the gynecologist it is useful only when it is deemed necessary to examine the spine, the posterior wall of the pelvis, and the back. 5. Genu-pectoral. As the name implies, the patient rests upon her knees and chest. One side of the face is supported by a low pillow. Her 92 A TEXT-BOOK OF GYNECOLOGY. thighs are at right angles to the pelvis, the knees somewhat separated, and the feet slightly projecting over the edge of the couch. In this position intra-abdominal pressure is practically suspended. If the introitus is not too narrow the vagina fills spontaneously with air and becomes ballooned. The uterus and pelvic contents sink toward the abdominal cavity and the fundus, unless crowded into the hollow of the sacrum or attached, falls forward. This position is useless for digital examination, because the vagina becomes greatly elongated. When a retro-displaced uterus cannot be restored in the ordinary way, it is invaluable. Small incarcerated fibroids and ovarian tumors with long pedicles can be more readily pushed out of the pelvic cavity in this position. Pessaries and tampons are often advantageously intro- duced before the patient turns upon her side. 6. Erect. In the erect posture intra-abdominal pressure is increased to its maximum, so that the pelvic contents sink lower than in any other position. For esthetic reasons it is not resorted to when, many times, valuable information might be obtained by so doing. It is particularly desirable to make an examination while the patient is erect after fitting a pessary. Excessive obliquities of the pelvis and deformities of the spinal column are made more conspicuous while the patient is standing. CHAPTER VI. PHYSICAL EXAMINATION.-(Continued.) GENERAL CONSIDERATIONS: In the schema given on the following page the senses of touch, sight, and hearing are the only ones given for purposes of physical examination. The sense of smell is also quite important; from the odor of vaginal discharges we can at least suspect malignant disease or the retained products of concep- tion when they become decomposed. I. IMMEDIATE Touch. Palpation. Position.-Palpation may be performed in any position, but inasmuch as its gynecological use is usually restricted to palpa- ting the abdomen, the level-dorsal and gluteo-dorsal are the most satisfactory ones. Method.-Both hands should be well warmed and laid gently upon the abdomen, with the palmar surface down, and the whole area manipulated between them. The pressure must at first be light and then gradually increased; unless this point is observed the contraction of the abdominal muscles will make the proce-. dure useless. By engaging the patient in conversation muscular tension can often be overcome. Deep inspiration with prolonged expiration will likewise suspend voluntary resistance. (Mundé.) Hegar and Kaltenbach recommend that the bladder and rectum be filled with water and rapidly emptied for the purpose of pro- ducing immediate relaxation. Anesthesia is often necessary. So-called phantom tumors will disappear as if by magic when the patient is anesthetized. The fingers should be spread out and the whole abdominal surface uniformly palpated. By going over region after region, it is possible to detect any abnormalities which may be present. In the supra-umbilical region the finger 93 TOUCH. METHODS OF PHYSICAL DIAGNOSIS. SIGHT. HEARING. Intermediate. Immediate. Intermediate. Produced sounds. Existing sounds. The sound. (a) External inspection. Percussion. Auscultation. (6) Mensuration. (a) Uterine. (c) Per speculum. (b) Vesical. (a) Aspirator. (a) Sounds caused by pregnancy. (b) Sounds caused by tumors. (c) Crepitation. (6) Microscope. Immediate. Palpation. Simple touch. Vaginal. b) Rectal. (c) Vesical. Double touch. Conjoined manipulation. (a) Vagino-abdominal. (6) Recto-abdominal. (c) Recto-vesical. The thermometer. 1. Vaginal. 2. Rectal. 3. Urethral PHYSICAL EXAMINATION. 95 tips should be directed upward and backward; in the umbilical, backward; and in the infra-umbilical, downward and backward into the pelvic cavity. In normal conditions the sensation is not unlike that of manipulating plastic fluid. Thickening of the skin, circumscribed areas of resistance, nodules, tumors, fluid collections, etc., should be looked for and mapped out. Regions of Abdomen.- For diagnostic purposes the abdomen is divided into re- gions, which are shown in Fig. 50. The following structures are found in these régions :- Right Hypochondriac.—Right lobe of liver; gall bladder; hepatic flexure of colon; part of duodenum; part of right kidney; suprarenal capsule. Epigastric.-Right half of stomach; pancreas; liver. Left Hypochondriac. - Spleen and narrow extremity of the pancreas; cardiac end of stomach; the splenic flexure of colon; upper part of left kidney; left supra- renal capsule; occasionally a part of left lobe of liver. Right Lumbar.-Part of the duodenum and jejunum; the ascending colon; lower half of right kidney. 4 driac. FIG. 50. 2 3 5 G 7 8 9 6 REGIONS OF ABDOMEN.-(Edis.) I. Right hypochon- 4. Right lumbar. 5. Umbilical. 6. Left lumbar. 3. Left hypochon- 7. Right iliac. driac. 8. Hypogastric. 9. Left iliac. 2. Epigastric. Umbilical.-Part of the omentum and mesentery; lower part of the duodenum, with some convolutions of the jejunum and ileum; transverse part of colon. Left Lumbar.-The descending colon; lower half of left kidney with part of the jejunum. 96 A TEXT-BOOK OF GYNECOLOGY. Hypogastric.-The uterus when in the gravid state; convolutions of the ileum; the bladder if distended. Right Iliac.-The termination of the ileum; the cecum, with the appendix vermiformis. Left Iliac.—The sigmoid flexure of the colon. Vaginal Touch. Position.-Preferably the level-dorsal for routine examination. English specialists prefer the lateral or latero-abdominal. It is often advantageous to practise touch in several positions. Method. The index finger of either hand may be used. It should be scrupulously clean and the nail reasonably short. Pure castile or antiseptic soap of some kind is the best lubricant. The vaginal orifice is most easily reached by sweeping the finger forward from the buttocks over the anus, perineum, and fourchette. Avoid contact with the clitoris if possible. The lax vaginal orifice in multiparæ makes it easy to find, and often the introduction of two fingers is necessary. In passing the finger or fingers into the vagina the examiner should note :- 1. Vulva.-If pain is caused by an attempt to introduce the finger the parts should be inspected for- (a) Inflammation, abrasions, or ulcerations; (b) Labial abscess; (c) Urethral caruncle; (d) Eczema vulvæ. Protrusions or tumors at the ostium vaginæ may be due to- (a) Cystocele or rectocele; (b) Procidentia uteri, the cervix presenting; (c) Inversio uteri, the fundus presenting; (d) Uterine and vaginal neoplasms; (e) Imperforate and bulging hymen. 2. Hymen.-Observe- (a) Carunculæ myrtiformes. Their presence indicate parturition at or near term ; (b) Whether perforate or imperforate. 3. Vaginal Walls.-Observe the degree of moisture and heat, PHYSICAL EXAMINATION. 97 the presence or absence of rugæ, fistulæ, foreign bodies, length and diameter of canal. Length. The walls are increased in length by- (a) The ascent of the uterus into the abdominal cavity, as in ovarian or fibroid tumors. They are shortened by- (a) Prolapsus uteri, with cystocele or rectocele ; (b) Ante- or retro-uterine displacements; (c) Inflammatory adhesions and cicatricial bands; (d) Congenital atresia, partial or absolute. Capacity. There is diminished capacity in- (a) Any of the conditions affecting the length; (b) Vaginismus ; (c) Tumors within the pelvis or vaginal walls. 4. Cervix.-Position.-It is lower than normal in the vagina in- (a) Prolapsus uteri; (b) Hypertrophic elongation. Direction. The direction may be nearly if not quite normal in flexions of the uterus. It points in- (a) Retroversion, directly forward; (b) Anteversion, directly backward; (c) Prolapsus, directly downward. Length. The normal length is nearly one inch. It is shortened physiologically in- (a) Pregnancy (apparent) and immediately before and during labor; (b) Multiparæ; (c) Advancing age. It is shortened pathologically in- (a) Super-involution; (b) Non-development; (c) Parametric exudations, obliterating vaginal forn- ices. It is increased in- (a) Hyperplasia, or hypertrophic elongation; (b) Prolapsus. Consistence.—It is hard in— (a) Senile atrophy; 7 98 A TEXT-BOOK OF GYNECOLOGY. (b) Fibroid and malignant degeneration; (c) Inflammation. It is soft in- (a) Pregnancy; (6) Early stage of subinvolution. 5. Os Uteri.-Shape and Size.-It may be- (a) Circular and smooth, as in nulliparæ; (b) Transverse and irregularly notched, as in parous women. In patency it varies in size from admitting a small probe to half an inch, or even an inch, in diameter. increased- (a) During menstruation (slightly); (b) In subinvolution; (c) In lacerations with erosions and eversions; It is (d) In ulceration, either malignant or non-malignant; (e) Shortly after labor and abortion; (ƒ) During the protrusion of some body-polypus, ovum, clot, inverted fundus, etc. 6. Vaginal Fornices.-Posterior Fornix.-After carefully examin- ing the cervix and os the finger should be carried around the cervix into the vaginal fornices. Normally, the poste- rior fornix has a feeling like that of the inside of the angle of the mouth (Hart and Barbour). When felt from below it is concave. Pathologically, it is rendered convex by any body or mass projecting through the pouch of Douglas. Such are- (a) Feces in the Rectum.-Fecal accumulations pit upon pressure, and if there is any doubt as to their character the bowel should be thoroughly emptied. (b) A Retroverted or Retroflexed Fundus Uteri.-Bimanual examination will fail to find the uterus in front. Unless pregnancy is suspected the sound may be used. (c) Acute or Chronic Inflammatory Deposits.—The history is that of inflammation with more or less immo- bility of the uterus. PHYSICAL EXAMINATION. 99 (d) Hematocele.-The history is that of shock and col- lapse, followed by the sudden formation of a tumor and inflammation. (e) A Prolapsed Ovary.-It may be adherent or non- adherent. If the latter, it can be pushed upward out of the pouch. The ovary is often beneath a retro-displaced fundus. It will be recognized by its size, shape, and, above all, its exquisite tender- ness upon pressure. (f) Small Fibroid Attached to Posterior Wall.-Absence of any history of inflammation or shock. The bimanual will show the fundus to be in front. The sound will indicate increased thickness of the posterior uterine wall. (g) Ascitic Fluid.-All of the fornices are impinged upon by a pressure which is non-resisting. Ab- dominal percussion and palpation will detect free fluid within the peritoneal cavity. Anterior fornix.-Except feces, any or all of the bodies or substances felt in the posterior fornix, may be felt in the anterior. The fundus uteri is often felt in front and is recognized by the sound and bimanually. Blood and inflammatory exudates rarely gravitate into the utero-vesical pouch unless the quantity is great, because the pouch of Douglas is the most dependent part of the pelvis. The normally located uterine fundus can always be felt through the anterior fornix by practising the bimanual. Lateral fornices.-The most frequent pathological con- dition felt through the lateral fornices is an effusion of either blood or the exudates of inflammation. Dilated Fallopian tubes are felt laterally, but rarely without the bimanual. In withdrawing the finger from the vagina after completing vaginal touch, the state of the perineum and pelvic floor should be noted. The perineal body may be partially or completely destroyed by laceration; or, there may be relaxation of the pelvic floor without any injury to the perineum. If so, a finger 100 A TEXT-BOOK OF GYNECOLOGY. placed in each lateral sulcus of the vagina, and separated, will detect the divided ends of the deep muscles and fascia beneath the mucous membrane. The character of the discharge on the finger should also be noted when it is withdrawn. Rectal Touch. Indications. In all instances where there is pain upon defeca- tion the rectum should be examined. When vaginal obstruc- tions exist, particularly in young girls with the hymen intact, a rectal examination may be the only one permissible. The retro- uterine structures and posterior wall of the uterus can best be explored through the rectum. I make it a rule to examine the rectum of every patient who consults me for the first time. Method.-The bowel should be thoroughly emptied by ene- mata. Wash the hand which has been used in the vaginal examination for fear of infection. Lubricate the examining finger with soap; fill the space under the finger nail with the same material by drawing the nail over a piece of hard soap. This is done to keep fecal or other matter from being introduced under the nail. The lateral position is the most convenient one. As the finger passes the sphincter, observe― (a) The resistance of the sphincter; (b) The presence or absence of tumors, fissures, etc.; (c) The presence or absence of strictures, malignant ulcer- ation, etc. After the finger has penetrated the rectum there will be detected a thick conical body projecting into the anterior wall, which is the cervix. The posterior wall of the uterus, the inter- vening pouch of Douglas, the sacral excavation, and the posterior rectal wall should all be touched. By exerting traction upon the cervix, per vaginam, the parts are much more accessible. The introduction of more than one finger is rarely necessary. For a thorough examination anesthesia and dilatation are often required. Vesical Touch. Indications.-Immediate vesical touch partakes of the nature of an operation, and hence is not resorted to except in the most urgent cases. Indeed, owing to the great danger of incontinence PHYSICAL EXAMINATION. ΙΟΙ following digital exploration of the bladder, the practice has fallen into pretty general disuse. It is safer and easier to enter the bladder, when necessary, through the incised vesico-vaginal wall. Intermediate vesical touch with the sound is, however, frequently practised. Double Touch. Method.-In double touch the index finger is introduced into the vagina and the thumb into the rectum; or, conversely, the thumb into the vagina and the index finger into the rectum; or the middle finger may be substituted for the thumb. It is useful in examining the recto-vaginal pouch and wall, as the structures coming between the fingers can thus be accurately appreciated. Conjoined Manipulation. In the schema three varieties of conjoined manipulation are given. These are: (a) vagino-abdominal, (b) recto-abdominal, (c) recto-vesical. Vagino-Abdominal.-This is by all odds the most important. The patient should be placed in the level-dorsal position with her abdominal walls as much relaxed as possible. This is best accomplished by drawing the knees up and slightly elevating the head and shoulders. The finger or fingers should not be removed from the vagina after practising simple touch until the bimanual has been per- formed. Simple touch is but the first step of a bimanual. The position of the two hands is well represented in Fig. 51. With the internal fingers the uterus and annexa, together with the pubic segment and anterior vaginal wall, are lifted up toward the brim. The whole abdominal area over the pelvic brim should be palpated with the external hand, which is gently but not spasmodically depressed. The first object of the examiner should be to locate the fundus uteri. Its normal position is about three inches above the border of the symphysis. By lifting the uterus upward with the internal fingers and pressing downward in the direction of the pelvic brim with the external hand, it will be, if in front, within the grasp of the two hands. If retro-displaced, the two hands 102 A TEXT-BOOK OF GYNECOLOGY. will approach each other with nothing intervening except the abdominal and vaginal walls. The normal virgin uterus is pear-shaped although com- pressed antero-posteriorly. Its entire length is three inches, of which nearly one inch is intra-vaginal. At the fundus it is nearly two inches wide and about an inch thick. Through the FIG. 51. CONJOINED MANIPULATION. abdominal and vaginal walls all intra-abdominal bodies seem larger than they really are. Nevertheless, an experienced examiner ought to detect even a slight increase in the size of the uterus, although he may not be able to determine its cause. Such enlargement may be the result of- 1. Pregnancy. The uterus has a regular, spherical outline, with an apparent equality of all diameters. There is a peculiar PHYSICAL EXAMINATION. 103 feel, even in early pregnancy, which must be felt to be ap- preciated. The cervix is soft and velvety. Vaginal dis- coloration is present. The uterus is freely mobile. 2. Subinvolution or Areolar Hyperplasia.-The uterus is more or less tender. Menstruation is not interrupted and is usually profuse. The cervix is not softened and is apt to be gaping. 3. Small Fibroid Tumors.-There is no tenderness, and menstru- ation is oftener profuse than otherwise. The uterine walls are irregularly thickened. In suspected pregnancy it is unwise to introduce the sound. Let the student be cautious in giving a positive diagnosis in early pregnancy. The best diagnosticians are liable to be mis- taken, and time is the only safeguard. It must not be forgotten that conception may occur when the organ is pathologically enlarged. The external hand should now be moved to one side and an effort made to compress the organs situated in the lateral portions of the pelvis. By rubbing the external fingers over the internal ones it is entirely possible, unless great obstacles exist, to outline the broad ligaments and the ovaries; when either are enlarged it is quite easily done. If the tubes are distended they are recognized as fluctuating, "sausage-like" masses on one or both sides. Successful bimanual examination requires skill and experience. A tactus eruditus results only from long practice. When once acquired it will bring to its possessor that which in no small degree goes to make a successful gynecologist. It is much more satisfactory with some women than with others. Tender- ness, rigidity, and thickness of the abdominal walls are interfering factors. The first two can be overcome by anesthesia: in deal- ing with thick abdominal walls, all that can be done is to relax them as much as possible by a favorable position. Recto-Abdominal.-What has been said concerning the in- formation derived from rectal touch will apply here. The external hand presses the contents of the pelvis toward the finger in the rectum, so that the posterior surface of the uterus. and the contents of Douglas's pouch are more readily reached. 104 A TEXT-BOOK OF GYNECOLOGY. By this method, too, retro-uterine tumors may be easily grasped from above; and a distended sigmoid flexure is more clearly determined. Recto-Vesical examination is described by some authors as though it were perfectly easy and safe. Personal experience teaches me that the urethra cannot be dilated so as to admit the index finger with impunity. Then, too, the movements of the finger within the bladder are so restricted as to make touch unsatisfactory. Its greatest utility is in determining the absence of the uterus; and even here very nearly, if not quite, as much information can be gained with the sound in the bladder and the finger in the rectum. CHAPTER VII. PHYSICAL EXAMINATION-(Continued). II. INTERMEDIATE TOUCH. UTERINE SOUND. Indications.-Unless counter indications present, it is the duty of the physician to employ every means at his command which will afford him information concerning his patient. The use of the uterine sound is, therefore, called for in those instances in which previous oral and bimanual examinations have not furnished satisfactory information, providing no counter indications exist. The examiner who has mastered the art of making the bimanual, will have occasion to resort to the sound less often than he who has not. Counter Indications.-I. It is not to be passed if there is any possibility of pregnancy; if menstruation is delayed for a few weeks, or even for a few days, the sound should not be employed. 2. It is not to be passed in cases of acute pelvic inflammation, and the greatest caution must be observed in cases of subacute or chronic inflammation. 3. With certain limitations, it should not be passed during ordinary menstruation. 4. It should not be passed in advanced malignant disease of the cervix or body of the uterus. Dangers.-Observing due precaution, Mundé, in fifteen thousand cases in which he has used the sound, has not had to contend with results more serious than slight shock and uterine colic. Nevertheless, it must not be forgotten that some uteri, even though apparently healthy, react upon the slightest provo- cation, and thus serious trouble may follow. Besides inflamma- tion, the student should guard against— 105 106 A TEXT-BOOK OF GYNECOLOGY. I. Perforation of the Fundus Uteri.-This is apt to occur when the organ is softened by disease or during the process of involu- tion after labor or abortion. The accident has happened repeat- edly, but fortunately it has not been followed by bad results. 2. Hemorrhage.-When an unnatural hemorrhage from any cause has existed, or is still present, there is danger of re-exciting or increasing it by the use of the sound. 3. Abortion. The examiner should never rely absolutely upon the patient's testimony, especially if there exist reasons for deception. As a safeguard against passing the sound into a pregnant uterus he should— (a) Always ask when menstruation last occurred; (6) Always examine the abdomen for signs of advanced pregnancy; (c) Always perform the bimanual previous to its introduc- tion. Even with these precautions, there are few men of extended experience who have not, during their career, unwittingly induced an abortion. Method of Employment.-Place the patient in the level- dorsal posture, well down to the end of the table. The cervix and fundus are previously located by digital and bimanual examination. The speculum may or may not be employed. By relying solely upon the sense of touch the direction of the uterine canal can be ascertained and any obstacles to the advancement of the sound more readily overcome. On the other hand, if the speculum is used, the vagina and cervical canal can be freed from septic matter-an important considera- tion; and by fixing the cervix with a tenaculum the operator can see exactly what he is doing. I therefore prefer, with few exceptions, to introduce the sound through the speculum. When no Speculum is Used.-Pass the index finger of the right hand, properly lubricated, into the vagina, and touch the anterior lip of the cervix (Fig. 52). Grasp the sound in the left hand and guide it, with its concave surface directed toward the concavity of the sacrum, into the internal os. Then- I. If the uterus is retro-displaced it is gently pushed onward with the concavity still directed backward until the internal os PHYSICAL EXAMINATION. 107 is reached. When the handle is elevated toward the symphysis the point of the sound will pass into the uterine cavity. 2. If the uterus is in normal position or ante-displaced, the concavity of the sound, after the point has passed into the cer- vical canal, is turned forward, when the handle is depressed toward the perineum. When the Speculum is Used.-If the bi-valve is used place the patient in the ordinary level-dorsal position; if the Sims, in the semi-prone. Wipe the vagina and cervix thoroughly with a 1: 2000 mercuric solution. Apply to the cervical canal FIG. 52. Method of Introducing the Uterine Sound. (Hart and Barbour.) impure carbolic acid. Next gently fix the cervix with a tenacu- lum and pass the sound as directed above. Probes should always be introduced through the speculum. Previous to introduction the sound should be given a curve corresponding to that of the uterine canal, as ascertained by the bimanual. Absolutely no force is to be used in its introduction. The tip of the handle is lightly grasped by the thumb and the first two fingers of the right hand, and the point, instead of being pushed, is rather coaxed and insinuated onward. In turning the sound, either within the cervix or the uterine cavity, observe the following facts: If the handle is twisted on its long axis the tip will be forced to sweep around the arc of a semicircle, as shown in Fig. 53, and serious injury to the uterus 108 A TEXT-BOOK OF GYNECOLOGY. may result. If, on the contrary, the handle is made to traverse the arc of a wide semicircle, the point remains fixed or nearly so, and no injury will ensue (Fig. 54). Information to be Gained by the Use of the Sound. 1. The caliber and permeability of the cervical canal. Normally it should admit the sound without difficulty. The caliber is diminished in- (a) Infantile cervices; (6) Acute flexions. (The stenosis is usually at the os internum.) (c) Mucous polypi blocking up the cervical canal. FIG. 53. FIG. 54. Incorrect Method of Turning Uterine Sound. (Hart and Barbour.) Correct Method of Turning Uterine Sound. (Hart and Barbour). 2. The length of the uterine cavity. In determining the length of the canal keep the finger upon that portion of the sound corresponding to the external os when the instrument is withdrawn. The size of the normal uterine cavity, from the os externum to the fundus, is two and a half inches. It is increased in— (a) Subinvolution ; (6) Metritis and endometritis ; (c) Tumors attached to the uterus, and polypi; (d) Pregnancy; (e) After labor or abortion. PHYSICAL EXAMINATION. 109 It is diminished in- (a) Infantile uteri : (b) Super-involution; (c) Senile atrophy. 3. The direction of the uterine axis. Normally it is inclined forward. It is altered in— (a) Retro-flexions and versions; (b) Ante-flexions and veisions; (c) Lateral displacements (usually the result of cellulitis); (d) Various degrees of prolapse. 4. The mobility of the uterus. In health it is freely movable and without pain. It is oftener fixed as a result of inflammation, but fixation may be due to many pathological conditions. 5. The connection existing between the uterus and certain tumors. Such are (a) Small tumors found in the anterior and posterior fornices of the vagina. If the tumor is the fundus uteri the sound will penetrate it, and, if not adhered, lift it out of its unnatural position. (6) Large tumors within the pelvic or abdominal cavities. The sound will show whether or not such tumors are intimately attached to the uterus. 6. The differential diagnosis between an inverted uterus and a polypus projecting into the vagina. The length of the cavity is increased in polypi; in inversion it is nearly, if not quite, obliterated, so that the sound penetrates the uterine cavity but a short distance. Bladder and rectal exploration are sometimes necessary. 7. The condition of the endometrium. It is roughened in inflammation and cancerous degeneration. Hemorrhage often follows its introduction when these conditions present. VESICAL SOUND. Indications. Its most frequent use is to explore the bladder for calculi or suspected morbid growths. In amputations of the cervix, or in vaginal hysterectomy, the sound should always be passed to determine the relation of the bladder to the uterus. IIO A TEXT-BOOK OF GYNECOLOGY. With the sound in the bladder and the finger in the rectum the presence or absence of the fundus uteri above the superior pelvic strait can be determined. III. IMMEDIATE SIGHT. EXTERNAL INSPECTION. Observe first the figure, the color of the face and lips and the expression of the eyes. This will give some information as to the temperament and general health. By examining the tongue and gums existing disorders of the digestive organs and blood can be detected. For inspecting the abdomen place the patient upon her back with the clothing perfectly loose. Note- (a) The size and shape of the abdomen; (b) The condition of the umbilicus, whether prominent, flush, or retracted; (c) The presence or absence of pigmentation; (d) The presence or absence of lineæ albicantes. These may result from distention of the skin due to any cause, and may be absent in women who have borne children; (e) The contractions of the uterus; (f) The movements of the fetus; (g) Irregularities upon the surface. In all cases when suspicions of pregnancy exist inspect the breasts. Observe- (a) Their size, whether plump or flabby; (b) The areolæ and enlarged veins ; (c) The nipples, whether full formed or retracted; (d) The secretion. In doubtful cases a slight secretion is of but little value for diagnostic purposes. Previously to making a digital examination inspect the vulvar region, particularly if the presence of specific disease is sur- mised. Observe— (a) The situation, whether normal or too far back; (b) The color and size of the labia ; PHYSICAL EXAMINATION. III (c) The condition of the perineum and the gaping of the vulvar orifice; (d) The size of the clitoris; (e) The color of the introitus vaginæ; it is increased in pregnancy; (f) The appearance of the meatus urinarius-presence or ab- sence of caruncles; (g) The character of the dis- charge; and (h) Eczematous eruptions. Digital Eversion of the Rectum for Inspection.-Place the patient in the dorsal or latero-abdominal position, introduce one or two fingers into the vagina and press the tips in the direc- tion of the rectum. It is possible to expose in this way the mucous mem- brane of the edges of the sphincter FIG. 55. and a portion of the anterior rectal DIGITAL EVERSION OF RECTUM wall. Fissures and other lesions in- volving this region of the anus are (Munde). thus exposed without the aid of a speculum. (Fig. 55.) PER SPECULUM. Vaginal Specula. Specular examination of the vagina is by no means necessary in all cases. It should, however, be made when previous digital examination reveals any condition the exact nature of which is uncertain. Such are: Hyperplasia of the cervix with or without lacerations; carcinoma; abrasions and ulcerations; granular vaginitis, etc. It is usually wise to resort to the speculum when the patient consults the physician for the first time, unless counter indications prevent. Counter Indications.-Atresia vaginæ; acute inflammation; imperforate hymen; hyperesthesia. In malignant disease it II2 A TEXT-BOOK OF GYNECOLOGY. should be used as seldom as possible and then with much care. Bi- and Tri-valve Specula.-Place the patient in the level- dorsal posture with the feet supported in stirrups. The instru- ment can also be introduced in the lateral posture. Grasp the speculum, well lubricated, in the right hand and press the rounded point of the closed blades into the vulvar cleft which has been separated by the left hand. The transverse diameter of the blades should correspond to the antero-posterior diameter of the vulvar cleft. When the latter is penetrated, turn the speculum so that the handles will be directed downward and gently push it into the vagina in the direction of the cervix. The handles are now expanded in such a way as thoroughly to expose the cervix, and fixed with the set screw or ratchet. It may be necessary to fix the cervix with a tenaculum. By greater expansion it is possible to expose the entire vaginal vault. The speculum should be gently withdrawn, care being observed not to pinch the vaginal mucous membrane between the blades. Uni-valve or Sims's.-Much pains must be taken to secure the proper latero-abdominal position. Unless this is done the use of this speculum will be disappointing. It is necessary to have intra-abdominal pressure almost, if not quite, suspended. Method of Introduction.-Select a blade of proper size and lubricate its convex surface. Grasp the end to be introduced in the right hand and gently lift the upper labium with the left hand. Introduce the point of the blade and the finger into the vaginal orifice, keeping the point directed well backward into the posterior fornix. With the left hand steady traction is now made backward, and slightly upward so as to elevate the upper buttock and admit more light. The proper method of holding the speculum is shown in Fig. 49. The table must be so placed as to permit light to enter the vagina: i. e. the buttocks should correspond very nearly to the center of a side window while the head of the table is drawn about eighteen inches to the right. When an assistant is present, she may lift the labium during PHYSICAL EXAMINATION. 113 the introduction of the speculum. If the anterior vaginal wall obscures the view of the cervix, it must be pushed out of the way with the depressor. This will rarely be the case if the patient is in the correct position and the speculum properly held. The cervix can, if necessary, be drawn into position with a tenaculum. Tubular or Cylindrical.-In England, where this speculum is most often used, the patient is placed in the lateral position, with the buttocks close to the edge of the couch. It may, how- ever, be introduced in any position. The exact location of the cervix must be carefully noted by previous indagation. Separate the labia with the forefinger and thumb of the left hand. The speculum previously lubricated is now grasped in the right hand and the tip introduced between the labia. Keep it well pressed against the fourchette so as not to pinch the tissues in front by crowding them against the unyielding pubic bones. With the side of the speculum corres- ponding to the tip in contact with the posterior vaginal wall, push it onward in the direction of the vaginal axis until the vaginal roof is reached. Upon depressing the distal end the cervix will project into it. Very often a tenaculum is necessary. The Sims speculum affords the most perfect and natural view of the cervix, vault of the vagina, and anterior vaginal wall. By it alone is it possible to appreciate correctly cervical lacerations and eversions. Both the bi-valve and tubular specula act as expanding instruments, and consequently the parts are put upon. the stretch. The principle of the Sims is entirely different, and there is no pressure exerted to congest or distort the tissues.. For operative purposes it is indispensable. What to observe in using a speculum. Note- (a) The color and condition of the vaginal mucous mem- brane; (b) The position of the vaginal walls; (c) The character of the discharge from.the vagina and cervix ; (d) The condition of the cervix and cervical canal. Look for congestion, inflammation, abrasion, ulceration, induration, and laceration; 8 114 A TEXT-BOOK OF GYNECOLOGY. (e) If there is laceration, hook a tenaculum in either lip, separate them and then endeavor to roll the parts in. In this way the extent of the laceration and the amount of cicatricial deposit can be determined. Rectal Specula. Indications. A specular examination of the rectum is called for in all instances when previous digital examination and ever- sion have not afforded necessary and precise information. This is usually the case when the disease is deep seated. Such are: Strictures, fistulous openings of a pelvic abscess, recto-vaginal fistulæ, proctitis, and internal hemorrhoids. Any or all of these lesions are not infrequently associated with pelvic and uterine disturbances. Method.-If the bi-valve is used, place the patient in the lateral posture. First insert the finger through the anus to over- come the resistance of the sphincter. After the distal ends of the blades are introduced push the instrument inward and back- ward until the handles or hilt approach the anus. So place the blades before introduction that, when opened, the diseased area will be exposed. Never turn the speculum within the rectum; to examine the walls obscured by the blades withdraw and reintro- duce it. Care should be taken not to pinch the rectal mucous membrane in withdrawing the instrument. If Anesthesia is rarely necessary for the above examination. a more thorough one is desired, the patient should be anesthe- tized and the sphincter dilated. This is done in the following manner :-Pass the two thumbs completely into the rectum with the four fingers of either hand resting upon either natis. Steadily but forcibly separate the thumbs until the fibres are felt to tear, or until they are arrested by the tuber ischii on each side. The rectal mucosa can now be examined with perfect ease as the canal is converted into a yawning cavity. The walls are best separated by two Sims specula, or with a large expanding instrument. As a therapeutic measure dilatation will again be referred to in considering the treatment of constipation. PHYSICAL EXAMINATION. 115 Urethral Specula. Indications.-Disordered micturition, when causes outside of the urethra are not discovered, calls for urethral inspection. The urethral lesions are: Fissure, ulceration, caruncles, and neoplasms. The only counter-indication is acute or recent in- flammation of the urethra. Method. The patient may be either upon her back or side. A reflected light will afford the best view. First pass a sound and locate any sensitive point; no pain should be caused by passing a sound into a healthy urethra. Now introduce the speculum or urethroscope so that the diseased area will be exposed. Gentleness and skill are imperative in exploring the deeper portions of the canal. IV. PRODUCED SOUNDS. PERCUSSION. To practice percussion, the patient may be placed in any posi- tion, depending upon the surface to be percussed. In gyneco- logical examinations it is practiced over the abdomen oftener than over any other region, hence the patient is usually placed upon her back. The middle finger of the left hand is placed flat upon the abdomen, at one time lightly at another firmly. With the tips of the middle fingers of the right hand strike the second phalanx distinctly. The sound elicited will indicate whether air or solid material lies underneath the finger. V. EXISTING SOUNDS. AUSCULTATION. Auscultation may be either immediate or intermediate. Its chief usefulness in gynecology is in differentiating pregnancy from other causes of abdominal enlargement. The sounds caused by fibroids are due to the large arteries which they con- tain. Crepitation results from peritoneal roughness and adhe- sions. Sometimes loose ascitic fluid within the abdomen can 116 A TEXT-BOOK OF GYNECOLOGY. be detected by a splashing sound induced by the patient suddenly changing her position. Mensuration, the use of the aspirator, and the clinical ther- mometer do not require special consideration. The uses of the microscope have been defined in Chapter IV. CONCLUSION. The schema of the Methods of Physical Diagnosis has been so arranged simply for the convenience of study. A limited number only, or all of the methods therein contained, may be necessary in any given case. It is not intended that the student shall proceed with his examination in the order given. The usual sequence of methods is as follows :— 1. External inspection. It may not be wise to inspect the external genital organs until after vaginal touch is practiced; 2. Digital examination of the vagina followed by the bimanual; 3. Inspection per vaginal speculum; 4. Introduction of the uterine sound; 5. Palpation, percussion, mensuration, and auscultation, if deemed necessary; 6. Examination of the rectum and the urethra if deemed necessary; 7. The use of the clinical thermometer, particularly during exacerbations of pain; 8. The application of the aspirator and the microscope as final tests. CHAPTER VIII. THE GENERAL PATHOLOGY OF GYNECO- LOGICAL diseases. PRELIMINARY CONSIDERATIONS. Many points bearing upon the pathology of gynecological dis- eases are as yet unsettled. Indeed, the greatest difference of opinion prevails concerning the importance of local lesions as disturbing factors. Cause and effect are constantly being mis- taken the one for the other. As a result we have in uterine pathology two distinct parties:- I. Those of the first party relegate to the sexual system of the female, when it becomes diseased, the power to affect the whole organism in a morbid way. This influence, it is main- tained, is exerted through the sympathetic and cerebro-spinal nervous systems; and, accordingly, the only way in which the symptoms resulting therefrom can be permanently relieved is by curing the local lesion. 2. Those of the second party, on the other hand, attribute the local trouble to systemic causes. They believe that the sexual organs exert but little, if any, influence on the general organism; and that by directing the treatment to the general and constitu- tional symptoms the patient can be restored to health without local interference of any sort. Again, those of the first party are by no means unanimous as to the importance and significance of certain local lesions. Thus Bennett and his followers gave to inflammation and ulceration an exaggerated importance: according to this school, sympa- thetic phenomena rarely occur except when the uterus is inflamed or ulcerated. Hewett and Hodge undertook to establish a special uterine pathology, based upon displacements, consider- ing inflammation and ulceration of little, if of any, importance as primary factors. Cervical lacerations constitute the founda- 117 118 A TEXT-BOOK OF GYNECOLOGY. tion of a pathology promulgated by men who revel in minor operative treatment. Disease of the uterine appendages is, by not a few, considered the chief cause of the ills which afflict woman-kind. The foregoing theories are the natural result of looking upon the female sexual organs as anatomical entities instead of but part of a series which, in their totality, constitute the organism. No restricted pathology has been, or will be, able to survive the rapid strides of gynecology. The physician who to-day ignores local lesions in the treatment of gynecological diseases is quite as culpable as he who would treat an amenorrhoea due to phthisis or chlorosis by stimulating the uterus. It may not always be possible to determine the order, but symptoms occur in patho- logical succession, and effects never precede their causes. NERVOUS AND BLOOD SUPPLY OF THE PELVIC ORGANS. Organs developed from a common primordial structure possess nerve communications whereby impressions originating in one may be transmitted to others of a like structural evolution. (Oliver.) From the temporary organs named Wolffian bodies, the reproductive and urinary organs are developed by a process of gradual evolution. There is, therefore, a perpetuation of direct nerve influence between the sexual and urinary organs. Indeed, there is a nervous and vascular connection existing between all of the pelvic organs. The same system of vessels and nerves supply largely the genital organs from the ovaries to the perineum, and are presided over by the same genito-spinal center. Consequently, all are involved to a greater or less degree in any physiological requirement which nature may impose upon any one. They participate alike in ovulation, men- struation, conception, pregnancy, parturition, and involution. (Byford.) A pathological process involving one organ is also likely to implicate others. So, too, the rectum and the bladder are physiologically and pathologically affected by similar influ- ences; or if primarily involved, may reflect any irritation origin- ating in them to the genital organs. Thus we see that derangement of any one organ within the pelvis may involve all; or, acting through the genito-spinal GENERAL PATHOLOGY OF GYNECOLOGICAL DISEASES. 119 center, may exert a powerful influence for evil upon the whole organism. Any system of uterine pathology, therefore, which ignores the unity of the pelvic organs, and of the entire organ- ism, must necessarily be imperfect. HOW DISTANT ORGANS ARE INVOLVED. Assuming, then, that distant organs are frequently affected by pelvic disease, it becomes the duty of the physician to study the modus operandi by which such affections are induced. In my opinion, hyperemia and hyperesthesia of the pelvic organs are essential factors in producing reflex symptoms in distant parts. That is to say, without hyperemia or hyperesthesia, no matter what the local lesion may be, there are no reflex symptoms. In proof of this statement I cite the fact that displacements, lacera- tions, and tumors of the uterus may exist for years without causing the least general disturbance, unless increased sensitive- ness or increased vascularity ensue. Again, the reflex symptoms starting from the pelvis are nearly all made worse by menstrua- tion, at which time the hyperemia and hyperesthesia are increased. It would not be correct, however, to infer from this that reflex symptoms inevitably result from hyperemia and hyperesthesia of the pelvic organs. On the contrary, every gynecologist meets with many cases where both are present, and in which no reflex phenomena whatever occur. NATURE OF THE LOCAL LESION CAUSING REFLEX Symptoms. Ovarian and uterine disease,-displacements, lacerations, in- flammation, subinvolution, congestion, etc.,— furnish the starting point of reflex symptoms oftener than other pelvic lesions. (Hegar, Schroeder.) Those of the urinary tract, the rectum, the coccyx, the perineum, and the anus are also frequently responsi- ble for such symptoms; in the latter list are fissure, lacerations, carunculæ, vaginismus, and coccygodynia. In these various lesions both hyperemia and hypersensitiveness may present themselves, either alone or combined. I20 A TEXT-BOOK OF GYNECOLOGY. FORMS OF HYPEREMIA. Hyperemia rarely exists except as a result of some definite cause, and in order to cure it the cause must necessarily be removed. According to Byford, it occurs in three forms :- (a) Active Hypertrophic Hyperemia, as in fungoid degeneration of the uterine mucous membrane, in fibrous tumors, in preg- nancy and in conditions of subinvolution. (b) Passive, Venous or Congestive Hyperemia, as when the blood is confined to the uterus by some obstruction to its return. Obstruction giving rise to this form of hyperemia may result from uterine displacements, from cervical lacerations, or from peri-uterine effusions. (c) Inflammatory Hyperemia, caused by inflammation. THE SEQUELA OF HYPEREMIA. Active Hypertrophic Hyperemia, if this theory be correct, gives rise to hypertrophy of the organ involved, because of the exaggerated local nutrition. It is seen physiologically in pregnancy and pathologically in fibrous tumors, fungoid endo- metritis, and subinvolution. Passive and Inflammatory Hyperemia give rise to fibrino- plastic effusion, which becomes organized. This contracts and cuts off the capillary circulation of the parts involved. The natural structure of the uterus is supplanted by the connective tissue thus formed, with resulting condensation and induration. This is hyperplasia. (Virchow). When it is once established, congestion and inflammation may entirely subside while hyper- esthesia remains. This is probably due to the fact that the terminal nerve fibers are involved in the condensation of tissue, reflex symptoms frequently resulting therefrom. The reflex symptoms in cervical laceration may result (a), primarily, from the involvement of terminal nerve fibers dis- tributed to the cervix by the cicatricial deposit, and (b) secon- darily, from the hyperemia and congestion caused by the lacera- tion and deposition of cicatricial tissue. The inflammatory form of hyperemia will account for those circumscribed points of induration so often found in the cervix GENERAL PATHOLOGY OF GYNECOLOGICAL DISEASES. 121 and in the walls of the fundus. They result from protracted vascularity of the part or parts involved. (Byford). Abrasion and ulceration of the cervix may follow in the train of hyperemia and inflammation. Abrasion is a frequent sequela; true ulceration from this cause alone is exceedingly rare. Both abrasion and ulceration result from impaired nutrition of the mucous membrane because of the hyperemia of the fibrous structure of the cervix. So-called granular and cystic degenera- tion of the cervix has for its basis hyperemia and inflammation. (Cazeaux.) THE NEUROSES. We have seen that in the condition called hyperplasia, hyper- emia may be absent. In these instances the pain is readily accounted for by the unnatural deposit of hyperplastic tissue. There are many cases, however, where the genital organs are exquisitely sensitive and yet where the most careful examination fails to reveal the evidences of disease. Congestion, inflamma- tion, abrasion, displacement—all are absent, and yet there is pain and sensitiveness in one or all of the pelvic organs, and reflex symptoms are innumerable. The form of dysmenorrhea known as "neuralgic" frequently occurs in connection with these symptoms. The older authors called a uterus thus affected “irritable.” The term is quite as comprehensive as is "neurosis." Both describe a condition, without defining its cause, and both are used to hide our ignorance. Patients rarely, if ever, die from this disorder, and if it has a pathology it is so chameleon-like in character that it has not yet been defined. How GENERAL SYMPTOMS ARE INDUCED BY LOCAL DISEASE. Disease of the genital organs gives rise to general symptoms in one of two ways: (a) by reflex irritation; or, (b) by deprav- ing nutrition. An irritation is conveyed to the genito-spinal center, and thence reflected to all organs with which this center communicates. In this way the stomach, bowels, liver and nervous system become implicated. That the stomach is oftener involved than any other organ, is shown by the nausea and vomiting so often present in early pregnancy. If the cause, other than pregnancy, persist, digestion is interfered with and, 122 A TEXT-BOOK OF GYNECOLOGY. sooner or later, the nutrition is compromised. The depraved blood does not carry to the nerve centers that which they need to sustain them and they become anemic. Exhaustion soon supervenes and often becomes profound, giving rise to nervous prostration or neurasthenia, a condition receiving detailed atten- tion in the chapters devoted to the HYSTERO-NEUROSES and to GENERAL TREATMENT. HOW LOCAL DISEASE IS INDUCED BY SYSTEMIC DISTURBANCE. Since nutrition may be affected from many causes, so-called nervous prostration frequently occurs when the pelvic organs are perfectly healthy. This condition is nearly always attended with circulatory disturbances. We know that the vaso-motor system presides over the circulation. It dilates and contracts the caliber of the blood-vessels, and wear and repair depend upon the proper adjustment of this function. If the equilibrium of the ebb and flow is disturbed, local anemia or local hyper- emia takes place. The cheeks are affected in this way when they become pale as a result of fear, or when they become reddened as a result of shame. This is physiological. The flushes of heat so frequently present during the climacteric period is another example which borders upon the pathological. If this equilibrium of the circulation is destroyed from any cause whatever, the internal organs are as often affected as is the skin. Such a cause may be mal-nutrition, nervous shock, or indeed anything that profoundly impresses the system. If the brain is involved, either insomnia or drowsiness occur, depending upon whether the brain is hyperemic or anemic. Flatulence, gastralgia, and nervous dyspepsia result when the stomach is similarly affected. The womb and the ovaries are oftener implicated than any of the internal organs, and become hyperemic or anemic as the case may be. If the former, con- gestion with all its concomitant symptoms-menorrhagia, leu- corrhea, tenderness, etc.,—occur without any local cause; if the latter, amenorrhea or scant menstruation. (Engelmann.) Hyperemia, congestion, and anemia of the uterus are likewise. frequently caused by those general or, organic diseases of the body which tend either to deprave the blood or to obstruct the GENERAL PATHOLOGY OF GYNECOLOGICAL DISEASES. 123 pelvic circulation in a mechanical way. The disorders especially tending to deprave the blood are enumerated in the succeeding section. The diseases of the lungs, liver and heart may congest the pelvic organs in a mechanical way. Menorrhagia, amenor- rhea, and ovarian irritation, or any other pelvic lesion, may therefore be due to general as well as to local causes. TEMPERAMENT AND CONSTITUTIONAL BIAS. In dealing with gynecological diseases, the temperament and constitutional bias cannot be ignored. One patient will, without suffering the least inconvenience, go through life with a pelvic lesion which, in another, would give rise to the most distressing symptoms. It is this fact which is responsible for much of the confusion which now prevails regarding the significance of the many pelvic affections. The constitutional bias presents itself in various ways. Any one of the several forms of dyscrasiæ may retard the convalescence. These are: tuberculosis, scrofulosis, syphilis, Bright's disease, the various blood disorders, malaria, etc. The innumerable symptoms which have long been defined by that now indefinite term, scrofulosis, are legion. It also has long served as a convenient name under which to conceal much ignorance. Were it possible to trace so-called scrofulosis to its original source, it is probable that the importance given by Hah- nemann to syphilis, psora, and "sycosis," using these terms in their broadest sense, would be better appreciated. At any rate, there often exists an obscure element which perpetuates indefi- nitely local lesions, especially the catarrhal diseases of the genital tract. In whatever form this element presents itself, it can be reached only by proper constitutional treatment. It is, then, clearly the duty of the physician, in dealing with the many gynecological affections, to differentiate cause from effect, when it is possible so to do, and to conduct his treatment accordingly. CHAPTER IX. GENERAL TReatment of GYNECOLOGICAL DISEASES. GENERAL CONSIDERATIONS I have endeavored in Chapter VIII to show the important part played by malnutrition in the causation of the diseases of women. The reflex symptoms are as numerous and varied as the figures of a kaleidoscope; hence, while they may serve as guides in selecting a remedy, they are too changeable to justify the phy- sician in discarding other methods of treatment. Many of these symptoms can be relieved by local treatment alone, especially if they are not of long standing; often they will vanish under the administration of a properly selected remedy; but not infre- quently it is absolutely necessary to combine with specific and local medication certain methods of dietetic, hygienic, and gen- eral treatment in order to relieve symptoms which may be either the result or the cause of pelvic disease. The general symptoms requiring special attention are the following:- I. Indigestion; 2. Constipation; 3. Nervous prostration. I. INDIGESTION. The stomach, as we have seen, is one of the first organs to become deranged in a reflex way. Under certain circumstances, as in some cases of pregnancy and hysteria, the stomach appar- ently rejects almost every particle of food taken into it, without seriously involving nutrition. In the vast majority of instances, however, prolonged disordered digestion leads to inanition and malnutrition, for, unless the patient can digest and assimilate the proper amount and kind of food, depraved nutrition is inevitable. 124 GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 125 The treatment of indigestion is considered under the sections devoted to constipation and nervous prostration. 2. CONSTIPATION. I am inclined to believe that the evils of constipation are under-estimated in the homeopathic school. Too much reliance is placed, by many, upon the indicated remedy, and too little upon certain adjuvants which are both useful and harmless. Constipation begets indigestion, headache, and local congestion. It is many times impossible to cure an irritable ovary or a con- gested uterus without first regulating the action of the bowels. The frequency of constipation in women is proverbial. It is much more common than in men, because of sedentary habits, confinement in ill-ventilated rooms, and, above all, improper conveniences. Habit in no small degree controls every function of the body, and especially defecation. If Nature's commands are ignored, she soon ceases to give them. In due time there is a sensory paralysis of the mucous membrane of the rectum, and the feces accumulate in large quantities without exciting the involuntary mechanism. Finally, the hardened feces give rise to fissure or hemorrhoids, and when pain becomes a factor defecation is postponed as long as possible. America has much to learn from Europe in making proper public provision for the accommodation and protection of women when away from home. In the treatment of constipation the first and essential requisite is to secure the coöperation of the patient. Without this all measures are futile. The habit must be reëstablished, and this often requires much time and perseverance. She should direct her thoughts to the necessity of the act at a certain hour each day before retiring to the closet, which should be done with clock-like regularity, whether the desire be present or absent. This is indispensable. The best time for making this effort is when the peristalsis is excited by a meal-preferably immedi- ately after breakfast. Fullness of the abdomen favors defecation, and a glass of water shortly before the act aids in producing a feeling of distention. Severe effort at straining should be avoided. The sense of leisure resulting from a proper position will encour- age gentle instead of violent effort. 126 A TEXT-BOOK OF GYNECOLOGY. The diet and ingesta are of equal importance. As constipa- tion is so often associated with indigestion, it becomes necessary to select the diet accordingly. In doing this there are several indications to be fulfilled: (a) the articles selected should not distress the stomach; (b) they should be such as the patient can afford; and (c) the cause of the constipation should be borne in mind, i. e., whether due to deficient secretion or to deficient peristalsis. Fruits are almost always advantageous. The kind of fruit should depend in a measure upon the cause of the constipation. They act by increasing the distention; by increasing the secre- tion because of their juices and acids; and by increasing peris- talsis because of the fibers, rinds, seeds, etc., which drop into the intestinal canal. Apples are almost always to be had in this country and fulfil the first two indications; if the rind is left on they excite peris- talsis as well. They should be eaten in the fore part of the day-before or after breakfast. The acid increases the intestinal secretion, and they are therefore especially useful when the stools are dry and hard. Oranges and lemons act in the same way. Peristaltic action, when there is great torpidity of the bowels, is quickened by fruits containing many seeds, as figs and the various small fruits. Most of the berries improve the function of the bowels because of the combined action of the seeds and acids-hence they are particularly useful in season. Canned fruits are apt to be too sweet, so that the uncooked varieties are at all times preferable when they can be had. Stewed prunes and baked apples are, however, often useful, and possess the advantage of being inexpensive. Many patients cannot take bananas because of the distress which they excite. Where this is not so they are very useful, oftentimes acting as a cathartic. On the whole, I much prefer acid to sweet fruits, because they increase not only the intestinal secretion but the hepatic as well. The coarser breads are always beneficial, and the more bran or hull of the grain they contain the better. Bran crackers, such as are used in most sanatoriums, fulfil the indications nicely. In the absence of these, and when the stomach will tolerate it, GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 127 I have often seen a teaspoonful of bran in a glass of water, drank the first thing in the morning, act in a most satisfactory manner. Pop-corn is often most efficacious, and in the consti- pation of pregnancy, with nausea and vomiting, it will sometimes relieve the stomach symptoms when everything else fails. Oat- meal and corn-meal gruels are likewise useful in exciting peris- talsis. If there be spasm of the sphincter ani muscle, with fissure or hemorrhoids, nothing short of dilatation under ether will prove of much avail. I know of nothing in the practice of gynecology more satisfactory than this operation, when indicated. Displacements of the uterus and ovaries may act in a mechan- ical way and obstruct the bowel. Indeed, mechanical causes should always be looked for in the treatment of costiveness in women. Rectal stricture may act in the same way, but organic strictures rarely occur in the female. I have had more than one case brought to me with a diagnosis of stricture made because of the constipation and the difficulty with which the inexperi- enced sometimes meet in penetrating the "third sphincter." In these cases forcible dilatation does much good. In great torpidity of the large intestine massage is very use- ful. Beginning at the right groin, and with a definite idea of the anatomy of the parts, the whole colon can be kneaded and squeezed in such a way as directly to stimulate its fibers to con- tract. This is best done just before an effort is made to move the bowels. At first this manipulation will excite much distress, unless practised with great gentleness, but after a few treatments it is not in the least disagreeable. In hydropathic institutions much reliance is placed upon water compresses over the bowels. I have no doubt of their utility under certain circumstances. If the bowels absolutely refuse to move in spite of the best directed general and local treatment, enemata will have to be resorted to. If there are evidences of impaction, some solvent may be used with the enema. Glycerin, olive oil, and ox-gall are the best agents for this purpose. The latter should be diluted with water (3j-Oj). I desire, however, to enter my pro- test against the indiscriminate use of enemata. It is quite as easy to make a "pauper of the rectum" by the use of the syringe 128 A TEXT-BOOK OF GYNECOLOGY. as by the use of cathartics. Of the two evils the former is the lesser, though in non-surgical cases enemata are rarely necessary. In gynecological practice cathartics are still more rarely called for, except in abdominal surgery. They are then used in the form of saline preparations for the purpose of promoting drain- age through the intestinal canal. Therapeutics. Hydrastis Can.-Constipation with headache and hemor- rhoids; AFTER STOOL, PAIN IN THhe rectum for HOURS; especially useful after purgative medicines; colicky pains, with sensation of goneness, faintness, and heat in the intestines. Much pros- tration. Collinsonia.-Constipation with hemorrhoids and a sensation as of sticks in the rectum; stools consist of dry balls of fecal matter; prolapsus uteri; flatulence and distention of the abdo- men; heat and itching of the anus, with portal congestion; HABITUAL CONSTIPATION. Sulphur.-Abdominal plethora and passive congestion of the venous system, causing a sensation of tightness and fulness in the abdomen, with feeling of repletion after partaking of but a small quantity of food (Farrington); constant urging to stool; pressing on the rectum as if it would protrude; rush of blood to the head; cold feet; faintness, especially at or about 10 or II A. M.; stools hard and knotty; general dulness of mind and body. Nux Vomica.-Constant ineffectual urging to stool; alternate constipation and diarrhea; sedentary habits; use of highly- seasoned food; stools black, hard, and often streaked with blood; hemorrhoids; RELIEF AFTER STOOL. Lycopodium.-ABDOMINAL PLETHORA IN ELDERLY WOMEN, WITH CONSTIPATION; large accumulation of gas in the bowels; desire and inability to expel the stool, with painful constriction of the rectum and anus; URIC ACID DEPOSIT IN THE URINE; irri- table and restless in the afternoon. Podophyllum.-Constipation, with descent of the rectum from a little exertion; feces hard, dry, and voided with much diffi- culty; flatulence and headache; MORNING AGGRAVATION OF ALL GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 129 INTESTINAL SYMPTOMS; weakness and soreness of the back; hemorrhoids. Consult :-Alumina, opium, bryonia, graphites, anacardium, conium, plumbum, sepia, silica, platina, pulsatilla, esculus hip., calcaria carb. 3. NERVOUS PROSTRATION. The terms nervous prostration and neurasthenia have, in Amer- ica at least, become almost household words. There are many factors capable of producing the state designated by these terms. Sometimes it is met with when hematosis and nutrition are seemingly unaffected; it is then usually due to nervous shock, or strain, or to deficiency of the menstrual discharge. Oftener, the mal-nutrition is prominent, which may be due to disordered digestion, loss of fluids, or nervous shock. The pathological succession frequently occurs in the following order: A pelvic lesion involves the stomach in a reflex way, and digestion becomes impaired; improper or insufficient food is taken, and in due time nutrition is compromised; anemia and chloro-anemia succeed as a matter of course, and not infrequently are made worse by excessive menstruation. The nerve cells are starved, as it were, for the want of proper nourishment, and the nervous system is thereby rendered unduly impressionable. If a woman thus affected be subjected to mental shock, or undue mental strain and worry, or sexual excesses, she is liable to become the victim of nervous prostration. Any or all of the symptoms studied under the head of the Hystero-Neuroses may be present in nervous prostration, and their relative importance is there considered. In the treat- ment of this state it becomes necessary to recognize the impor- tant fact that the patient's nutrition is depraved, and if she is to be raised from a state of chronic invalidism to robustness, this must be improved. The backache, the leucorrhea, the menstrual irregularities, the pain in various parts of the body, the paralyses, and the psychoses are to receive due attention in a symptomatic way. But the local trouble and the general disturbance result- ing from depraved nutrition must not be ignored. With the loss of appetite there comes wasting of fatty tissue, and the patient 9 130 A TEXT-BOOK OF GYNECOLOGY. takes to her bed, where, unless she can be made to eat and take on flesh, she is likely to remain. The profession is indebted to Dr. Weir Mitchell, more than to any other man, for defining the principles upon which the suc- cessful treatment of nerve prostration is based. These princi- ples may be summarized as follows 1. Seclusion and Rest.-The patient should be removed from home or other accustomed environments for at least six or eight weeks, placed in bed, and only allowed to sit up gradually. 2. Massage. This is to be applied in a most thorough man- ner by an experienced masseuse, the séances lasting for half an hour at first, the time being lengthened until the full limit-an hour and a half-is reached. 3. Electricity. The interrupted current is used twice daily, and so applied as successively to work nearly all of the muscles of the body twice daily. 4. Diet.—Milk is given every hour, at first in small quanti- ties, then gradually increased until, under the action of massage and electricity, the patient is able to take large quantities. Dr. Mitchell practically ignores internal medication. From a somewhat extended experience in this class of cases in both hospital and private practice, I am satisfied that much good is to be derived from properly selected homeopathic remedies. It is surprising how quickly, under this treatment, the strength improves, the lost adipose tissue returns, as well as the lost vital- ity and the power of locomotion. The following case, recorded by Playfair,* I quote in full, because of the acknowledged eminence of the author, and also because it demonstrates most forcibly the utility of the treatment even in the most desperate cases. It is, too, a remarkable instance of the multiform phe- nomena so characteristic of neurotic disease:- CASE. "The case must be well known to many members of the profession, since there is scarcely a consultant of eminence in the metropolis who has not seen her during the sixteen years her illness has lasted, besides many of the leading practitioners in the numerous health-resorts she has visited in the vain hope of benefit. My first acquaintance with the case is somewhat curious. About two months before I was introduced to the patient, chancing to be walking along the * "Nerve Prostration and Hysteria," Playfair, p. 101. GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 131 esplanade at Brighton with a medical friend, my attention was directed to a remark- able party at which every one was looking. The chief personage in it was a lady reclining at full length on a couch, and being dragged along, looking the picture of misery, emaciated to the last degree, her head drawn back almost in a state of opisthotonus, her hands and arms clenched and contracted, her eyes fixed and staring at the sky. There was something in the whole procession that struck me as being typical of hysteria, and I laughingly remarked, 'I am sure I could cure that case if I could get her into my hands.' All that I could learn at the time was that the patient came down to Brighton every autumn, and that my friend had seen her dragged along in the same way for ten or twelve years. On January 14th of this year I was asked to meet my friend, Dr. Behrend, in consultation, and at once recognized the patient as the lady whom I had seen at Brighton. It would be tedious to relate all the neurotic symptoms this patient had exhibited since 1864, when she was first attacked with paralysis of the left arm. Among these-and I quote from the full notes furnished by Dr. Behrend-were complete paraplegia, left hemiplegia, complete hysterical amaurosis; but from this she had recovered in 1868. For all these years she had been practically confined to her bed or couch, and had not passed urine spontaneously for sixteen years. Among other symptoms I find noted awful suffering in spine, head, and eyes, requiring the use of chloral and morphia in large doses. For many years she had convulsive attacks of two distinct types, which were obviously of the character of hystero-epilepsy. The following are the brief notes of the condition in which I found her, which I made in my case-book on the day of my first visit. I found the patient lying on an invalid's couch, her left arm, paralyzed and rigidly contracted, strapped to her body to keep it in position. She was groaning loudly at intervals of a few seconds from severe pain in her back. When I attempted to shake her right hand she begged me not to touch her, as it would throw her into a convulsion. She has now many times daily, frequently as often as twice in an hour, both during the day and night, attacks of sudden and absolute unconsciousness, from which she recovers with general convulsive movements of the face and body. She had one of these during my visit, and it had all the appearance of an epileptic paroxysm. The left arm and both legs are paralyzed and devoid of sensation. She takes hardly any food and is terribly emaciated. She is naturally a clever woman, highly educated, but, of late, her memory and intellectual powers are said to be failing. "It was determined that an attempt should be made to cure this case, and she was removed to the Home Hospital in Fitzroy Square. She was so ill, and shrieked and groaned so much on the first night of her admission, that next day I was told that no one in the house had been able to sleep, and I was informed that it would be impossible for her to remain. Between 3 P. M. and 11.30 P. M. she had had nine violent convulsive paroxysms of an epileptiform character, lasting, on an average, five minutes. At 11.30 she became absolutely unconscious, and remained so until 2.30 A. M., her attendant thinking she was dying. Next day she was quieter, and from that time on her progress was steady and uniform. On the fourth day she passed urine spontaneously, and the catheter was never again used. In six weeks she was out driving and walking, and within two months she went on a sea-voyage to the Cape, looking and feeling perfectly well. When there, her nurse, who accompanied her, had a severe illness, through which her ex-patient nursed her most assiduously. + 132 A TEXT-BOOK OF GYNECOLOGY. * She has since remained, and is at this moment, in robust health, joining with pleasure in society, walking many miles daily, and without a trace of the illness which rendered her existence a burden to herself and her friends." There is another and large class of neurasthenic women who are well enough to be about, and the causes of their disease can be corrected by fresh air and exercise. These cases exhibit the entire range of mild mimetic and hysteric symptoms. Moral advice, resolute will, and proper hygiene are often all that is ne- cessary. Hysterical joints frequently present in this type of patients. They are much more easily dealt with than the “ha- bitually bed-ridden, couch-loving invalid," of whom Dr. Play- fair's celebrated case is a typical example. The amount of nourishment taken under the conditions de- scribed is marvelous. Patients who are able at first to take almost nothing at all, and as a result have become pale, anemic, and wasted, will soon consume at each meal a quantity of food which is simply astonishing. In one of Dr. Playfair's patients the treatment was commenced on October 16th with three ounces of milk every third hour. On October 30th the following was consumed with relish: "5 A. M., ten ounces of raw meat soup; 8 A. M., cup of black coffee; 9 a. M., plate of oat-meal porridge, with a gill of cream and a tumbler of milk; 12.30 P. M., milk; 1.45 P. M., whiting, bread and butter, rump-steak, cauliflower, omelette, and a tumbler of milk; 4 P. M., milk; 5 P. M., milk and bread and butter; 7 P. M., fried haddock, chicken, cauliflower, apple and cream, and a glass of Burgundy; 9.30 P. M., milk; 11 P. M., raw meat soup. (The milk between 8 a. M. and 9.30 P. M. amounted to two quarts.)" • It is possible for this amount of food to be consumed by a nervously prostrated woman only under suitable conditions. By seclusion she is cut off from all harmful sympathy and excite- ment; by rest she conserves all her energies; and by massage and electricity passive exercise is substituted for exertion with- out any of its evils. Proper seclusion can rarely be had at home because of the close proximity to sympathetic relatives and friends. It is cer- tainly impossible without a thoroughly good nurse-one pos- sessing sufficient will-power to keep from the invalid's room all GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 133 who exert a harmful influence. A greater degree of liberality may be admitted in dealing with patients who retain the power of self-control. Massage, to be thoroughly done, should be applied by a trained masseuse. It can, however, be easily learned by any in- telligent person who is sufficiently strong. With the patient lying in a blanket, the masseuse begins at the feet by taking up the skin and thoroughly pinching it all over. The toes are twisted in all directions and the small muscles kneaded with the ends of the fingers and thumb. The large muscles of the legs are grasped alternately with both hands. Dr. Mitchell recom- mends smearing the parts with some nutrient lubricant, prefera- bly cocoa butter. Striking the large muscles very often with the palms of the hands constitutes an important feature of mas- sage. The hands and upper extremities are manipulated in the same way, working upward. In working the abdomen the patient should lie flat on her back with the knees drawn up. Commencing with the skin, it is pinched all over and the walls are firmly grasped, first with one hand and then with the other. The hands are now placed one on each side just below the ribs and the flesh drawn forward in the direction of the colon. This part of the treatment is particularly important if the patient is suffering from indigestion. The posterior surface of the body is gone over in the same way, the patient lying flat upon her face and abdomen. The whole of the back is treated, com- mencing at the nape of the neck and passing downward on each side of the vertebral column. The skin and muscles are pinched and the two fingers of the right hand, one on each side of the vertebræ, are made to sweep downward the entire length of the spine. This is to be repeated a number of times. If there is spinal irritation there will be some difficulty in doing this, but by gradually approaching the sore spots they can be thoroughly treated, the local sensitiveness being in time entirely destroyed. This is true in hyperesthesias of other regions, and with perseverance and patience, even ovarian irritation can be made to vanish. For the first two or three days the séances should not be longer than twenty minutes, but by the end of a week they may be continued from one to 134 A TEXT-BOOK OF GYNECOLOGY. two hours twice a day. The patient must be taught to relax all of the muscles by remaining perfectly passive. The use of electricity comprehends the application of the slowly interrupted induction current to nearly every muscle of the body within reach. By this means they are thrown into active contraction. This gives decided exercise to the muscles and greatly supplements the action of massage. Finally, the tonic effects of electricity are obtained by passing for ten or fifteen minutes, from the neck to the feet, a mild current with rapid breaks. When fat and anemic women become victims of nervous prostration it is Dr. Mitchell's practice to put them at rest, and "under-feed" them with milk until the flesh is materially reduced, when they are subjected to the usual treatment already described. The wisdom of local interference before placing a patient under the rest cure must depend upon circumstances. As a rule I believe it wise always to make a thorough examination, unless the patient's nervous system is liable to be greatly shocked by so doing. If, in married women, there are tears of the cervix or perineum, which evidently play an important part in the pros- tration, and if the degree of prostration is not such as to prohibit it, an operation is indicated at once. This is emphat- ically so if excessive hemorrhage can be controlled by repair- ing the tears or by curetting. On the contrary, in the unmar- ried, when the local symptoms are not urgent, it is best to ignore local measures, other than the hot douche, until the patient has regained sufficient strength to enable her to undergo such treat- ment as may be necessary. There are but few instances where the hot douche, judiciously given, does not act beneficially. The remedy most homeopathic in nervous prostration will, in the majority of instances, be one capable of profoundly impressing the system when given in health. The various phases of hysteria are covered by the milder remedies, but when emaciation becomes marked, and hematosis seriously dis- turbed, it is necessary to select a remedy profound in its action. If properly selected it should not be repeated too often, nor should it be changed until it is evidently no longer indicated. I GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 135 prefer to base the prescription in these cases upon constitutional symptoms, i. e., actual tissue changes, controlling, if necessary, urgent nervous outbreaks or manifestations of pain with inter- current remedies. However, if the chief remedy is properly selected, the intercurrent one will rarely be called for. Therapeutics. Arsenicum Album.-Great fear, trembling, cold sweat, REST- LESSNESS, and PROSTRATION; expression anxious and distressed; face pale, yellow, waxy, with edematous swelling; dryness of the mouth, with red streak down middle of tongue and redness of the tip; loss of appetite, with INCREASED THIRST; long-lasting nausea, with fruitless retching; VOMITING IMMEDIATELY AFTER EATING OR DRINKING; menses too early, too profuse, and very exhausting; WARMTH ALMOST ALWAYS RELIEVES THE PAIN. Calcaria.-Depression and melancholia; apprehensive mood; face pale, bloated, with blue rings around the eyes; after milk, nausea and some eructations; water brash; after eating, press- ing pain in the stomach, as if from a load or stone; hard disten- tion of the abdomen; MENSES TOO EARLY, TOO LONG, AND TOO PROFUSE; membranous dysmenorrhea; oppression of the chest ; tendency to tuberculosis; COLD HANDS AND COLD FEET; relax- ation of the tissues, with goneness and weakness. Calcaria is oftener indicated in fleshy, anemic women than in the emaciated. Ferrum.-Nervous, hysterical feeling; pettish; least contra- diction angers; throbbing pain on top of head when moving suddenly; FACE ASHY PALE OR GREENISH, BECOMING FIEry red UPON THE LEAST EXCITEMENT; face pale, with red spots; pale- ness of all the mucous membranes; vomiting as soon as food is taken; diarrhea, with undigested food, or constipation, with stools hard and expelled with difficulty; menses too late, long lasting, and profuse; PALPITATION OF THE HEART, WITH THROb- BING OF ALL THE BLOOD-Vessels; anasarca. The more clearly BLOOD-VESSELS; homeopathic iron is to any given case, the smaller the dose required to accomplish the desired end. This is true of any remedy, but preeminently so of iron. The fact remains that in certain cases of anemia iron as a pabulum will do much to improve the patient's condition when specific indications do not 136 A TEXT-BOOK OF GYNECOLOGY. present. Five or ten drops of ferrum dialysatum, twice or thrice a day with meals, will often work wonders when the smaller doses fail entirely. This dose is not large enough to precipitate hemoptysis and subsequent phthisis, which has been done by full doses.* Iodium.—Excessive excitability; face pale, yellow, sallow, and distressed; EATS FREELY, YET LOSES FLESH ALL THE TIME; alternate canine hunger and loss of appetite; constipation alter- nating with diarrhea; mammæ dwindle away and become flabby; induration and swelling of the uterus and ovaries. Ignatia.-Desire to be alone; nervous prostration following excessive grief or joy; clavus hystericus, relieved by lying upon the painful spot; head feels sore and bruised; choking sensation extending from stomach into throat (globus hystericus); spinal irritation; stiffness in the nape of neck; paralysis after great mental emotion. Phosphoric Acid.-Cerebro-spinal exhaustion from overwork; "The least attempt to study causes heaviness, not only in the head, but in the limbs."-Farrington. "Hysteria in women of dark complexion during the change of life.”—Hering. Meteor- istic distention of the abdomen with rumbling and gurgling; painless stools; urine looks like milk (phosphatic), or clear and passed in large quantities; menses too early and too long; amenorrhea; ovaritis and metritis from debilitating influences. Silicea.-Patient dreads any exertion either of mind or body; numbness of the toes, fingers, and back; spinal irritation; VIOLENT PERIODIC HEADACHE IN VERTEX, OCCIPUT, OR FOREHEAD, BETTER BY WRAPPING THE HEAD UP WARMLY; constipation, due to inac- tivity of the rectum; profuse, acrid, corroding leucorrhea; increased sexual desire with spinal affection; night sweats. Sulphur.-Face pale and eyes sunken; menses suppressed or too late and of short duration; bearing down in pelvis toward *"The treatment of anemia by iron is one of the few satisfactory and certain things in modern medicine, and we who believe in the supreme value of the homeopathic method may not neglect it because it does not seem conformable thereto, unless we can do better. That we cannot is the general confession; we must, therefore, give our anemic patients the iron they need, in whatever quantity may be necessary.' Hughes. 11 麒 ​GENERAL TREATMENT OF GYNECOLOGICAL DISEASES. 137 genitals; BURNING OF SOLES OF FEET AND WANTS THEM UNCOV- ERED, or feet cold and sweating; heavy, unrefreshing sleep; skin rough, scaly, or scabby, with itching; worse in a warm bed. Consult :-Lachesis, pulsatilla, sepia, aurum, picric acid, china, cocculus, hyoscyamus, and lycopodium. CHAPTER X. LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. GENERAL CONSIDERATIONS. That local gynecological treatment has been and is now much abused cannot be denied. This, however, is no more reason why it should be discarded in toto than that internal medication should be discarded because it has been and is now abused. This statement is made with a full consciousness that there yet exists a small party in the homeopathic school who not only deny the necessity of any local treatment or measures whatever in the treatment of the diseases of women, but even contend that local examinations are unnecessary and reprehensible. I do not desire to take issue with those who honestly hold this view, other than to state that it does not seem to me, from personal observation, that the interests of the school are best subserved by such unlimited faith in the efficacy of the homeo- pathic remedy. More than once I have had patients come to me from the hands of physicians who ignore local exami- nation and treatment, with cancer advanced beyond the operative stage, and with long-existing local lesions which were readily cured by local measures. I therefore do not hesitate to affirm it as my belief that the physician who to-day, with our knowledge of reflexes and malignant disease, refuses to grant his patient the benefit of local measures when general ones have failed, or declines to make a local examination if there is the least suspicion of malignancy, is culpably remiss in his obligations and should be held legally responsible for his neglect. THE VAGINAL DOUCHE. Only since the thermic properties of the vaginal douche have been appreciated has it been systematically employed as a therapeutic agent. It has long been used, however, for cleansing 138 LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 139 purposes, and although Dr. Eminet published some twenty years ago the advantages to be derived from using large, hot douches, there are yet many in the profession who do not comprehend, simple as it is, the technique of a properly administered douche. The simile used by Emmet is a good one for the purpose of impressing the patient with the importance of using much water and having it hot. It is the well-known blanched appearance of the hands of a washerwoman after having them in hot water for some time. When first immersed they become red because the primary (temporary) action of the heat is to dilate the vessels and.capillaries, thus causing congestion; in a short time the heat contracts the vessels, drives the blood from them, and the hands become white and shriveled. Contraction of the vessels is, therefore, the secondary and more permanent action of heat; the object to be attained in using a vaginal douche for thera- peutic purposes is this secondary contraction. This can only be accomplished by using water in large quan- tities and at the proper temperature. The quantity should not be less than one gallon, preferably two and often three. The temperature should range from 95° to 120°, depending upon the local condition and the susceptibility of the patient. Indications. The douche, as a therapeutic agent, is indicated in almost all conditions where pathological congestion is present. Thus, in the various catarrhal and inflammatory affections of the uterus and endometrium, in pelvic cellulitis and peritonitis, and in vaginitis, its use is invaluable. For cleansing purposes it is indicated whenever there is an offensive discharge from the vagina and after menstruation. Large quantities of hot water thrown into the vagina immediately preceding an operation upon the uterus or vagina is an exceedingly valuable hemostatic, and in plastic operations will prevent the loss of much blood. Method.-When vaginal injections are given for therapeutic purposes it is best to have such apparatus as will put the patient to the least possible inconvenience. The most conscientious are too apt to neglect any method of treatment which becomes irksome. I therefore prefer some method of conducting the fluid into the vagina which requires no physical effort. This can be done either with a siphon syringe, or, better still, with 140 A TEXT-BOOK OF GYNECOLOGY. a vaginal irrigator (Fig. 56). I have my dealer keep constantly on hand a supply of these irrigators holding two gallons. They can be made cheaply at any tin-shop, and are, therefore, inex- P.H.SCHMID NEW-YOR! FIG. 56. VAGINAL IRRIGATOR. pensive. The rubber tubing should be at least six feet long, and should possess a clip or cock by which the stream can be controlled. The nozzle should be of hard rubber and perforated at the sides only. If there is an opening at the center there is great danger of water passing into the uterine cavity. If made of metal it becomes heated by long contact with the hot water. Emmet maintains that an interrupted current, such as is. derived from any of the bulb syringes, is more effective. If so its advantage is more than offset by the exertion necessary to force a large amount of water into the vagina. In taking the douche the patient should lie upon her back with the hips somewhat elevated. The advantages of this posi- tion are the outlet of the vagina is higher than its vault, so that the canal is completely distended by the fluid; the hips are higher than the trunk proper, so that gravitation aids in relieving the venous congestion. It becomes necessary in this position to make some provision by which the fluid can be taken care of after it passes from the vagina. If economy is an object, this can be accomplished by placing the patient across the bed, her hips projecting well over the side and her feet resting upon two chairs. By placing a rubber sheet under her and properly shaping it, the water is conducted to a receptacle on the floor. A regular douche pan is, however, always to be preferred when obtainable. Beginning with a temperature of 95° F., it can be gradually increased by adding hot water until the maximum, 120°, is LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 141 reached. It should not be used hotter than this, and when the treatment is first begun it is well to advise the patient not to exceed 110° for the first few treatments, because occasionally the douches cause some sickness when too hot. The nozzle should be inserted well into the posterior fornix, behind the cervix. Unless this precaution is taken there is danger, if the os is patulous, of passing it into the cervical canal. The irrigator should be suspended at least three feet higher than the body in order to insure the necessary force. The size of the douche and the frequency of its repetition must necessarily depend upon circumstances. As a general rule, when used for therapeutical purposes, twice a day, the last given just before retiring, is not too often, and two gallons of water each time not too much. For hemostatic purposes three and even four gallons should be used. After a douche of this kind the mucous membranes exposed to the water will be found almost white and bleed but little when cut. For disinfecting purposes a much smaller quantity of water is required—enough, however, to cleanse the parts of all fetor. I do not advocate the vaginal douche in the treatment of the diseases enumerated, as a cure-all. It is to be looked upon only as an adjuvant though a most important one. I often pre- scribe it in the leucorrhea of virgins and young girls when an examination is not imperative, and frequently this is all that is necessary in the way of local measures. But to prove effective the patient must be impressed with the importance of observing the proper quantity and temperature of the water, the proper position, and, above all, of persevering for weeks or months. The thermic qualities of a vaginal douche are undoubtedly the most important from a therapeutical standpoint. Much good may be accomplished by adding to the water some medicament, -hydrastis, calendula, eucalyptus, etc.,-depending upon the indications which present. When special indications for any par- ticular remedy exist it is my custom, especially if no other form of local treatment is being pursued, to add a tablespoonful of the agent selected to the last pint of water used, instructing the patient to lie upon her back for fifteen or twenty minutes that the remedy may remain in contact with the diseased parts for 142 A TEXT-BOOK OF GYNECOLOGY. that length of time. Antiseptic and disinfecting injections are composed of: carbolic acid, 1-200; bichlorid of mercury, I– 4000; permanganate of potash, 1-100; bicarbonate of soda, I-20; and salicylic acid, 1-1000. Counter Indications.-Nothing more than a cleansing douche should be given during pregnancy, for obvious reasons. However, the mortal fear which some women have of throwing even a small quantity of water into the vagina while pregnant is absurd. Of course, if there is a predisposition to abortion the pregnant woman cannot be too cautious, but, in the vast majority of instances, nothing but good results will follow the occasional use of a small tepid douche. This is particularly so if there exists an irritating leucorrhea. The douche should not be used during normal menstruation. When the menstrual discharge is excessive because of actual disease it can then be administered for its hemostatic properties. This treatment is invaluable in dealing with hemorrhage the result of fibroma uteri. A cleans- ing douche should, however, follow the cessation of the men- strual flow if there be any fetor. LOCAL APPLICATIONS. There is nothing which more confuses the average student than the question of local applications in the treatment of gyne- cological diseases. This is owing to the fact that, even in the homeopathic school, each author and teacher has his favorite local remedy or remedies, and, unfortunately, empiricism is yet rife in the use of most of them. As a rule, the physician will accomplish more by learning how to use intelligently a few well- selected applications and confining himself to them, than by at- tempting in an aimless fashion to run the whole scale. In ordi- nary routine work I rarely have occasion to go outside of the following list:- Glycerin; Boro-glycerid; Iodin (compound tincture); Hydrastis ; Calendula ; Carbolic acid. : LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 143 I think that I have learned how to use these agents. Their special indications will be mentioned in discussing the various lesions in which they are useful, and it is only necessary in this chapter to deal in a general way with their properties and the method of their application. Glycerin.-Glycerin, in technical parlance, is designated a hydragogue, because of its power to produce a free watery dis- charge from mucous surfaces. In hyperemia of the pelvic organs and in inflammatory conditions, whether subacute or chronic, it relieves the congestion by extracting from the blood its serum. In almost every application to the cervix and the vagina, glycerin is used either as a vehicle with which to mix a more active remedy, or for the purpose of medicating the tampon which is finally to be introduced. It is a most important auxiliary to the vaginal douche. The best method of applying it is through a speculum, with tampons of cotton-wool well saturated with it. These should be inserted daily, and the nurse should, therefore, be instructed how to introduce them. Various instruments have been devised for the purpose of enabling the patient to intro- duce them herself, but all are more or less unsatisfactory. In multiparæ it is often possible to pass a medium-sized tampon through the ostium vagina without the aid of any instrument. Boro-glycerid.—This preparation is made by adding to four fluidounces of glycerin one ounce of powdered borax and rub- bing them well together in a mortar until the borax is thoroughly dissolved. I first began to use this remedy upon the recom- mendation of Dr. Wylie of New York. The borax seems to intensify the action of the glycerin in hyperplasia with much induration, or else it exerts its own action upon tissues thus affected. At any rate, it seems more efficacious than pure glycerin, where the products of inflammation are felt through the fornices and where there is hyperplasia and subinvolution, with acrid leucorrhea and exaggerated menstrual discharge. In aphthous ulceration of the vagina or cervix-a rare disease in adults it is almost a specific. Boro-glycerid is also an anti- septic of no mean value. Iodin. Churchill's tincture is the preferable preparation. It consists of seventy-five grains of iodin and ninety of iodid 144 A TEXT-BOOK OF GYNECOLOGY. of potassium to the ounce of alcohol. Iodin applied to the congested cervix and vaginal mucous membrane acts upon the capillaries, causing their contraction, and upon the lymphatics, stimulating them to absorb the exudation of plastic lymph in pelvic inflammations and the hyperplastic tissue in areolar hyperplasia. Its use is, therefore, indicated in subinvolution with or without hyperplasia, in inflammatory deposits, in chronic ovaritis when the ovary is enlarged and prolapsed, in chronic corporeal endometritis, and in cervical catarrh with abrasion. It may be applied directly to the cervix, the corporeal mucosa, or the vault of the vagina. It is best applied to the cervix by means of an applicator properly wrapped in absorbent cotton. The cervix should be previously cleared of all discharge. Any excess of iodin should be expressed by pressing the applicator against the side of the bottle. The whole vault of the vagina may be painted with the drug in the same way. Caution should, however, be exercised in the intra-uterine application of iodin. I rarely use it unless the os is patulous and drainage perfect. It should then be applied by carrying the applicator well up to the fundus, permitting it to remain for a minute or two. This enables the uterus to contract upon the cotton, bringing the medicament into contact with its entire lining inembrane. Iodin, in the cases enumerated, should be applied from one to three times a week. Instead of making direct application in the manner described, it may be diluted with glycerin (1-4) and applied upon a tampon. Indeed, if there is much hyper- plasia, and rapidity of action is important, it is advisable to introduce a tampon thus saturated instead of using one dipped in pure glycerin or boro-glycerid. The tampon can be left in the vagina from twelve to twenty-four hours. As a general rule I prefer making the direct application of the iodin, supple menting its action with the boro-glycerid tampon. The proper application of iodin is painless. Pain may result from contact of the drug with the skin surface by awkward manipulation. This is immediately overcome by the application of glycerin. If the patient at her next visit complains of having experienced some distress, and if the tampon removed LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 145 is blood-stained, it is well to lengthen the intervals between the treatments, or the iodin may be diluted by adding glycerin. In the preparatory treatment preceding trachelorrhaphy in cases where there is much hyperplasia I rely largely upon the hot douche, the compound tincture of iodin, and the boro- glycerid tampon. Under this treatment it is surprising how quickly hyperplastic tissue will melt away. The pressure exerted by the tampon is a curative factor soon to receive attention. Hydrastis Canadensis.-The chief indication for the local use of this drug is a profuse, stringy leucorrhea, with extensive glandular involvement. It is especially useful where the consti- tutional symptoms suggest its internal administration as well. As an intra-uterine application in chronic endometritis it is both safe and beneficial. A very serious objection to the drug as a local measure has been its staining properties. Pharmacists have now overcome this by the production of a colorless extract which seems quite as efficacious as is the original preparation. Hydrastis may be applied directly to the parts by the aid of an applicator, after which a tampon saturated in hydrastis and glycerin (1-4) should be placed against the cervix. By so doing it is longer in contact with the diseased parts-an important consideration, particularly if vaginitis complicates the endo- metritis, as it so frequently does. Calendula.-Calendula is to purulent endometritis with erosion what hydrastis is to glandular involvement with a tenacious, stringy discharge. The cervix has a red, corroded, granular appearance, due to solution of continuity, which gives rise to a purulent leucorrhea. It is questionable whether or not calendula exerts any power as an antiseptic.* It at least acts admirably in suppurating wounds of all kinds, and in purulent conditions is the sheet anchor of many homeopathic physicians. South- wick says: "Following some surgical operations, after the patient has used the ordinary cleansing douche, I direct her to mix two teaspoonfuls of the tincture with half a pint of warm water, to inject it while lying on her back, and retain it ΙΟ *I do not believe that calendula is a germ destroyer. +" Practical Gynecology,” p. 39. ! 146 A TEXT-BOOK OF GYNECOLOGY. from twenty minutes to half an hour. The non-alcoholic preparation is preferable.” In chronic endocervicitis Cowperthwaite* recommends the following: Hydrastis, one ounce; calendula, one ounce; glyc- erin, four ounces. Of this a tablespoonful is diluted in four ounces of water and used as an injection once or twice a day. This was also a favorite prescription of the late Dr. A. I. Sawyer. Personally, I prefer to use the remedies singly. Carbolic Acid. This agent is an old and well-tried disinfect- ant, and its use is limited to disinfecting purposes by many physicians. As such, it is used in the form of a douche, the strength varying from one to five per cent. Carbolic acid is, however, something more than a mere disinfectant. It is, in addition, antiseptic and anesthetic in its action. As an antiseptic, I am in the habit of swabbing the cervical canal with the "impure" acid before the minor operations upon the cervix or the uterus. But it is its anesthetic properties which seem to me the most valuable. When there is great hyperesthesia of the mucous membrane at the internal os-which may exist in women of all ages, but is oftener met with at or about the change of life —a thorough application of carbolic acid, even though dilatation is not practised, will often relieve distressing nervous symp- toms in a most remarkable way. An occasional application of the acid to an eroded cervix will act as a mild stimulant, supple- menting the action of iodin and other remedies when they have seemingly ceased to do good. After curetting in fungoid endo- metritis, the impure acid should be applied to the entire endo- metrium. In the ordinary run of cases these remedies cover nearly every indication and have the advantage of being both mild and harm- less in their action. However, this chapter would be incomplete without considering those less often called for. *" Text-book of Gynecology," p. 165. + Impure or commercial carbolic acid, as prepared by Dr. Squibb, is not a caustic, as is the pure. LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 147 ASTRINGENTS AND STYPTICS. Tannin.—The one indication for tannin can be summed up in the word "relaxation." In rectocele and cystocele, with sub- involution of the vaginal walls, the application of tannin, as recommended by Mundé, is most useful. He applies it by dip- ping a glycerin tampon into the powdered tannin. It is styptic as well as astringent in its action, and is therefore useful in vas- cular conditions of the cervix and vagina. Alum. This is also an astringent, and is used by many specialists in preference to the tannin where there is much relax- ation of the parts. I do not believe that it possesses any specific properties when used locally. Its greatest sphere of usefulness lies in its power to control hemorrhage after plastic operations which cannot be controlled by ordinary hot injections. Used as a saturated solution it is most effectual, and possesses the advantage of not forming clots, as does iron. Iron. When iodin, tannin, or alum fail to control hemor- rhage, iron, in the form of persulphate or perchlorid, will have to be resorted to. The large clots which it forms makes it an undesirable, if not a dangerous, hemostatic to use within the uterus. Nevertheless, it is sometimes necessary to utilize its more powerful styptic properties in cases of intractable hemor- rhage. NARCOTICS. Chloral Hydrate.-A solution is prepared by dissolving one drachm of chloral hydrate in one ounce of glycerin. In cancer of the cervix a tampon saturated in this and applied directly to the ulcerated surface will often afford marked relief. Opium. The aqueous extract may be used in carcinoma uteri. It should be applied directly to the parts by means of an applicator or upon a tampon. Conium mac.-Conium is useful in cancer of the uterus, particularly if indicated internally, where there is much infiltra- tion of tissue with induration. It is a favorite remedy of many homeopathic physicians for the relief of the shooting, darting pains which so frequently attend cancer in any part of the body. Belladonna.-Belladonna exerts a specific influence in acute 148 A TEXT-BOOK OF GYNECOLOGY. and subacute inflammatory lesions of the pelvic organs when the distress is aching and throbbing in character. It may be used as a cerate (one drachm to one ounce of vaseline) or in the form of the fluid extract. DISINFECTANTS. Iodoform.-Iodoform is also both antiseptic and anesthetic in its action. My chief use of this valuable agent within the vagina is after plastic operations. It may be sprinkled upon a glycerin tampon and thus applied, as a strip of iodoform gauze may supplant the ordinary tampon. Eucalyptus Globulus.-Eucalyptus is frequently combined with hydrastis, or it may be used by diluting one drachm of the oil in one ounce of glycerin. This is applied in the ordinary way when there is an offensive discharge from the vagina from whatever cause. Boracic Acid.—A boracic acid lotion of the strength of two drachms to the pint of water makes an excellent application in pruritus vulvæ from whatever cause. It may be applied to the cervix in the form of powder, through a powder blower, where erosions exist. This is also a convenient way of applying iodo- form. CAUSTICS. I have practically discarded the use of caustics in gyneco- logical work, and am sure that my patients are the better for it. The use of caustics about the cervix is, I believe, wrong in principle. Terminal nerve filaments can be squeezed quite as well by the cicatrix of caustics as by the cicatrix of tears. There has been no greater curse to womankind than nitrate of silver. By its use abrasions and ulcerations of the cervix may be healed, but it is done at the sacrifice of that principle which to-day is so well recognized as the essential one in the practice of gynecology. I have more than once met with the most obstinate reflexes which followed in the train of its use. The powerful solutions recommended in virulent vaginitis are, I believe, unnecessary and may do harm. At least one case of adhesive vaginitis has come under my observation, the result of LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 149 such an application. When a caustic is needed for surgical purposes the actual cautery is by all odds preferable to nitrate of silver, chloride of zinc, or the more powerful acids. THE VAGINAL TAMPON. The use of the vaginal tampon as a carrier of medicinal agents has already been referred to. The material from which it is made is not altogether unimportant. There is nothing which excels the cotton-wool now on the market. It is soft, elastic, and never "balls up," as does the ordinary cotton. Unfortunately, it is rather expensive, but I am sure that when intra-vaginal pressure is an object, as it is in dealing with inflammatory exudates and hyperplasia, the extra cost is more than compensated for by the superiority of the tampon thus made. If, on the contrary, pres- sure is not important, the ordinary cotton or absorbent cotton may be used instead. Tow or marine lint, lamp-wicking (Fos- ter), the roller bandage, and sponges have all been used and have their advocates. Except in cases of emergency I do not think that the use of sponges for tampons is justifiable. Cotton can be made into any desired shape, depending upon the use for which the tampon is intended. If its function is merely to keep a medicament in contact with the cervix, it should be soft, of disk-shape, and the string loosely tied about it. If, on the other hand, it is to support the uterus, it should be more compact and cylindrical. Cylindrical tampons can be quickly made in large numbers by spreading out a roll of cotton-wool or cotton (the ordinary unglazed commercial cotton is nearly if not quite as good for this purpose as the absorbent), and again winding it tightly into rolls about one inch thick; loops of strings are placed at intervals of two inches, between which the roll is cut. This will make a number of tampons one inch thick and two inches long-a very good size for the vaginal pouches. The string should be sufficiently strong to guard against breaking. Indications.-The vaginal tampon is used- 1. As a carrier of medicament to be applied to the cervix or vagina; 2. To control hemorrhage; 150 A TEXT-BOOK OF GYNECOLOGY. 3. In uterine and ovarian displacements; 4. To retain other bodies in utero, such as stem pessaries, tents, etc.; 5. After operations. 1. As a Carrier of Medicaments.-The soft glycerin plug is the most serviceable tampon for this purpose. By spreading out a sufficient quantity of cotton-wool on the palm of the hand a large quantity of glycerin can be poured into it before shaping the tampon, which can be conveyed into the vagina without soiling the fingers or the clothing of the patient. Any other substance may be added to the glycerin. This is applied directly to the diseased parts. A dry roll of cotton should be placed below this to keep it in position. 2. To Control Hemorrhage.-All clots should be first removed, and, if the exigencies of the case are not too great, the vagina thoroughly cleaned with a bichlorid solution (1: 3000). Soft cotton tampons soaked in carbolic solution (1:200) are first firmly packed with the dressing forceps into all of the fornices of the vagina. Another plug is next placed directly over the external os, after which the vagina is packed to its utmost limit. The vaginal tampon should not be used in hemorrhage from abortions after the fourth month. The cotton may be medicated with some astringent-iron, tannin, or alum-instead of soaking them in the carbolic solution. 3. In Uterine or Ovarian Displacements.-There are many patients suffering from these displacements, particularly ovarian, who can tolerate no other form of support. Preparatory to the introduction of a permanent pessary the vaginal tampon is often necessary. In retroversion a cylindrical tampon is first passed into the anterior fornix, so as to push the cervix back- ward and the fundus forward. One or two more, depending upon the capacity of the vagina, are placed against this to retain it in position. In anteversion the same number are introduced into the posterior fornix. In both retro- and ante- flexion the supporting tampon must be placed into that fornix which is impinged upon by the fundus. In flexures the relief afforded by tampons is due more to the elevation of the entire uterus than to the straightening of its axis. In ovarian dis- LOCAL TREATMENT OF GYNECOLOGICAL DISEASES. 151 placement a soft, medicated tampon is placed against the diseased organ. 4. To Retain Other Bodies in Utero.-When a stem pessary is introduced after dilatation, or when tents are introduced for the purpose of dilatation, a tampon is necessary to retain them in position. 5. After Operations.-In plastic operations, especially upon the cervix, a large tampon smeared with glycerin and iodoform should be placed in such a way as to relieve the sutures from tension while the patient vomits. A strip of iodoform gauze may be used instead, and for this purpose is even preferable. Vaginal tampons can be inserted through any form of specu- lum, though Sims's is by all odds the preferable instrument where hemorrhage is to be controlled. In removing the speculum the tampon, or tampons, should be held in place with the dressing forceps. If introduced for the purpose of controlling hemor- rhage they should not be left in longer than eight or ten hours, for, no matter how carefully prepared, they soon become offen- sive and irritating. When resorted to for the purpose of exert- ing pressure or support they may be retained for twenty-four or even forty-eight hours. In all instances their removal should be followed by an antiseptic douche. The patient should always be instructed how to remove them. Traction should be made backward in the direction of the perineum instead of forward. Where more than one is introduced the patient or the nurse should be told the number; they are then removed in the order indicated by the number of knots in each of the cords. When used to control hemorrhage the physician should remove them through a Sims speculum. CHAPTER XI. ELECTRICITY IN GYNECOLOGY. Electricity as a therapeutic agent has for many years been used more or less extensively by the vast majority of the medical profession in the treatment of general diseases. In the treatment of gynecological affections it has not been so com- monly used. This is probably due to three reasons: (a) A general knowledge of the physics of electricity does not pre- vail. (b) It is generally believed that elaborate and costly apparatus is necessary for its successful application. (c) In its application in the diseases of women the absence of specific indications makes precision difficult. (a) While a profound knowledge of the physics of electricity is under all circumstances desirable, it must be remembered that, unlike the neurologist, the gynecologist deals with organs closely grouped together in the pelvis; and that instead of applying the agent for its effect upon nerves and the reaction of muscles, he applies it to overcome perverted nutrition, hyper- esthesia, and local congestion. It is, then, only necessary for the gynecologist to understand the peculiar properties of the cur- rent which he may wish to use, and to know which pole of the galvanic current will produce irritation, which one absorption, sedation, anesthesia, etc. (6) For all ordinary gynecological work costly apparatus is a luxury, but not a necessity. One can get on very well with a good battery, and a few special electrodes. For the application of the very powerful galvanic currents (which are not so much used as formerly), a powerful battery together with a milliam- pèremeter, rheostat, etc., is necessary. (c) In undertaking to formulate specific indications in the schema appended, I have drawn largely from the writings of Grandin, Rockwell, Mundé, Massey, King, F. H. Martin, and 152 ELECTRICITY IN GYNECOLOGY. 153 - Apostoli. In it I have endeavored to reflect in small compass the more generally accepted rules, in order to simplify the appli- cation of electricity in the treatment of the diseases of the female pelvic organs. In those instances in which there is a conflict of opinion I have been, in large measure, governed by the weight of authority as well as by personal experience. The reader is referred to the several excellent text-books mentioned in the foregoing paragraph for theoretical amplifica- tion and exhaustive detail. As the galvanic and the faradic currents are the ones oftenest used in routine gynecological work, it is only necessary in this chapter to define what is meant by them, and the apparatus by which they are generated, referring but briefly to the Franklinic current. GALVANISM. The galvanic current is generated by the decomposition of two dissimilar metals immersed in some fluid. It is continuous, chemical in its action, and starts from the affected plate toward the one least affected. The plate least affected, therefore, receives the electricity and gives it off at its external extremity, and is known as the positive pole; the external extremity of the plate most affected is known as the negative pole. The action of these two poles is very different when applied to living tissue, and the intelligent application of galvanism requires a knowledge of this difference. The following are the essential properties of the two poles: The positive pole is anesthetic, the least painful, and its tendency is to check hemorrhage and cause absorption. The negative pole is irritating and caustic in its action. It is, therefore, more painful than the positive and its tendency is to produce hemorrhage and destroy. (Grandin.) If the destructive currents are used the difference in the cica- trices produced by the two poles is important. According to Apostoli the cicatrix formed by the positive pole is hard and retractile; while that produced by the negative is soft and non- retractile. 154 A TEXT-BOOK OF GYNECOLOGY. FARADISM. The faradic current, unlike the galvanic, is interrupted and is chiefly mechanical in its effects. If it possesses any chemical action it is very slight, and in gynecology it is used chiefly to stimulate the uterus by virtue of its power to induce muscular contractions.* The faradic current is thus generated: An insulated conjunc- tive wire of a galvanic battery is coiled on itself and laid on an insulated surface. Around this is placed another coil of insu- lated wire in which instantaneous currents are induced by the galvanic current passing through the inner coil. From the first of these coils of insulated wire the primary current is derived; from the second, the secondary. The two together constitute the helix. A bundle of soft iron wire placed in the center of the helix greatly intensifies the current derived from the induction coil. "When the current of the generating cell passes through the helix the soft iron is magnetized and draws the interrupter (rheotome) in contact with it. This breaks the circuit and demagnetizes the iron. The interrupter is then returned to its former place by a spring. This step reconnects the generat- ing cell with the helix, and again allows the iron to be magnetized. The interrupter is again drawn in contact with it. Thus the current is constantly broken and restored by a simple device known as an 'interrupter,' or ' automatic circuit-breaker.” An induced current within the iron core of the helix is thus produced. This is the current which passes through the elec- trodes to the patient.”† The difference in the action of the two poles is not nearly so marked as in the galvanic current, though the positive is more sedative and the negative more stimulating. The primary or inducing current is more useful in stimulating muscular con- traction where sedation is not important; the secondary, or induced current, is more useful where sedation is called for. * The sedative properties of the secondary faradic current are now known to be most useful in relieving pelvic pain. † Ranney, “Electricity in Medicine," 1885, p. 5. ELECTRICITY IN GYNECOLOGY. 155 THE FRANKLINIC CURRENT. I find the franklinic current exceedingly useful in the treat- ment of nervous prostration with spinal irritation and hysterical pains in various parts of the body. No disturbance of the clothing is required in its application unless the wet electrodes are used. The sparks are induced by a self-charging plate rotation multiplier. The voltage of each spark induced is very great, depending upon its length-according to Thompson, fifty-three thousand volts per centimeter. While the quantity of electricity conveyed by the sparks is exceedingly minute they are capable, because of the great pressure at which they are delivered, of powerfully stimulating the cutaneous nerve terminations. The sensation elicited where the sparks strike the skin is that of a needle-thrust. The superficial muscles are also more or less excited, especially if the wet electrodes are used. APPARATUS. In the selection of a galvanic battery two essentials are im- portant: it should contain a sufficient number of elements to produce a current strong enough for routine gynecological work; and the elements should be so constructed as to require the least possible attention. There are many excellent batteries on the market and but few really poor ones. The chlorid of silver dry-cell galvanic batteries are rapidly gaining in favor, as there is no fluid to spill, and they require but little attention. They are made by the J. A. Barrett Company, of Baltimore. Of the fluid batteries infinite varieties are on the market. The McIntosh and the Waite and Bartlette are old and well tried instruments. It is claimed that the high internal resist- ance and low electro-motive force of the Dry-cell makes it less desirable for gynecological work. The objection will, in time, undoubtedly be overcome. It is quite as difficult now-a-days to obtain an inferior faradic battery as an inferior galvanic. The Kidder Tip-cup battery and the McIntosh are very 156 A TEXT-BOOK OF GYNECOLOGY. popular. I have in constant use McIntosh's "Little Gem" Cabinet Battery, Waite and Bartlett's thirty-cell portable galvanic battery and the Atkinson Four-plate Töpler static machine, and have every reason to be satisfied with all. GALVANOMETER. The accurate application of galvanism is not possible without some means by which the intensity of the current can be measured. It is true that the number of cells brought into the circuit is something of a guide, but inasmuch as there exists such a marked variance in the internal and external resistance, this is a rough and very inaccurate method, when a very strong current is used. An instrument for this purpose is known as a galvanometer or milliamperemeter. A milliampère is the unit of electrical measurement, and for routine gynecological work from five to forty milliamperès are quite sufficient. Most milliampèremeters now made are capable of registering intensities as high as one thousand milliampères. WATER RHeostat. The rheostat is an instrument devised for the purpose of modifying the intensity of the current of electricity by passing it through resistance coils or water. This is almost indispensable in treating the organs of special sense, the brain, etc., and the gynecologist will likewise find it of special utility. The water rheostat is the simplest and most practical, and in it the cur- rent is regulated by the distances between the ends of the metals which are immersed in the water. ELECTRODES. The instruments by which electrical currents are applied to the body are called electrodes. In their application to the pelvic organs special electrodes have been constructed. They are external and internal. The ordinary external electrode consists of a handle to which is attached a metallic plate covered with a sponge. The sponge is, however, unsatisfactory, uncleanly, and not a good conductor. The plates of sheet-lead or block-tin are much preferable in ELECTRICITY IN GYNECOLOGY. 157 gynecological electrotherapy, being readily adapted to the external surfaces of the body because of their pliability. They can be covered by any inexpensive material of good conducting quality (chamois, absorbent cotton, rough toweling, etc.) which can be quickly changed for each patient. The size of the external electrode should be governed by the intensity of the current used. Manufacturers are apt, unless the size is specifically stated, to furnish those which are altogether too small. When very powerful currents are used, i. e., currents of over sixty milliampères, they should be dispersed over as large an area externally as possible. To accomplish this Apostoli uses potter's clay with which to cover the abdomen, and Engelmann plates of sheet-lead of the following dimen- sions: 3½ x 4½ inches; 4½ x 64 inches; 6½ x 9½ inches. These can be applied over the abdomen or back while the patient is in almost any posture. The object of internal electrodes is to utilize the several cavities within the pelvis in order to more effectually localize the electric current. They are, therefore, made to adapt them- selves to the cervix, uterus, vagina, rectum bladder, etc. When the positive pole is used direct within the uterus the electrode should be of platinum. Dr. F. H. Martin has devised for the purpose a very ingenious, flexible electrode. GENERAL CONSIDERATIONS. By the term direct application is meant the application of the one or the other pole directly, or as nearly so as possible, to the organ or organs diseased. This is accomplished by selecting a proper internal electrode (vaginal, uterine, urethral, rectal, etc.), the other pole being applied externally, usually over either the abdomen or the sacrum; or by the concentration of the current through the medium of a bi-polar electrode. By the term indirect application is meant the application of both poles externally, one electrode usually being placed over the abdomen and the other over the sacrum. In young unmarried women, unless the symptoms are urgent, it is advisable first to resort to this method. 158 A TEXT-BOOK OF GYNECOLOGY. The conductivity of electrodes is increased by dipping them in warm water, and the superficial revulsive effect of the galvanic current is increased by using for this purpose salt water. The time, length, frequency, intensity and manner of the applications will necessarily vary with each case. The séances should last from five to thirty minutes. For routine work I rarely exceed fifty milliampères, and often use only five or ten. Due regard must be paid to the function of menstruation, and should there be any acute or subacute inflammatory symptoms, direct electrization, at least, should not be practised for the first few days preceding or following the expected period. In amen- orrhoea, on the contrary, the molimina should be watched for, and the applications made a week before and during their appearance. Some patients will tolerate much more electricity than will others. Idiosyncrasy should always be noted, and the strength and duration of the current regulated accordingly. THE APPLICATION OF THE FRANKLINIC CURRENT. The franklinic current may be administered in various ways. The most common method is as follows: The patient is placed upon an insulated platform and is connected with the ball sur- mounting one of the Leyden jars by means of a conducting cord. The other pole is connected with a ball electrode having an insulated handle. After the current is created by revolving the plates, the electrode is applied through the clothing to the painful parts and up and down the spine. In the indirect method, the second conducting cord, instead of being attached to the ball electrode, is placed on the floor near the platform, for the purpose of creating a certain degree of induction. The electrodes passing through the balls which surmount the Leyden jars are drawn beyond sparking distance. After the current is created sparks are drawn from the patient by a suitable ball or sponge electrode. The "electric bath" or "static breeze" is administered, with or without the insulated stool, by using a point electrode or a static crown instead of the roller or ball electrode. The patient is fanned by a gentle current of electrified air, which produces a ELECTRICITY IN GYNECOLOGY. 159 delightfully cooling sensation, and which is exceedingly useful in dealing with neurasthenic cases. The faradic current may be created by the static machine in the following way: The conducting cords are inserted in the two sockets on the front edge of the base, the free ends being attached to the metal electrodes. The switch is opened and the sliding electrodes closed. The discharge is then regulated by separating the sliding electrodes. With a separation of one- sixteenth of an inch a very smooth faradic current is obtained; a separation of one-quarter of an inch, on a large machine, will afford a current quite as powerful as the strongest nerves can endure. Let it be remembered that while electricity, in many instances, may be the chief therapeutic agent, it is rarely the only one to be used. It must be supplemented by other treatment, both constitutional and local. Again, it must be used patiently, per- sistently, and with discrimination. It is impossible to cure symptoms like amenorrhoea and dysmenorrhoea, when due to constitutional causes, by local electrization. Unless the cases are properly selected failure will be inevitable. I purposely omit giving the technique of electro-puncture as practised by Apostoli, Keath, Engelmann and others in the treatment of hyperplasia and fibroma uteri, for the reason that I consider this treatment unsurgical and unscientific. Candor compels me to state that this somewhat dogmatic conclusion is not based upon personal experience, but rather upon deductions drawn from principles which seem to me clearly defined in deal- ing with surgical conditions, and upon observation. Patients have come to me who have been subjected to almost insufferable agony by the method of Apostoli without the least benefit, and not a few cases have come to my knowledge in which the out- come has been fatal. In the light of surgical data furnished by Bantock, Thornton, Tait, Leopold and others, the results do not seem to justify the means. 160 A TEXT-BOOK OF GYNECOLOGY. APPLICATION. AMENORRHEA. The cases of amenorrhea in which electricity is useful must be selected with discrimination. In all instances the benefit to be derived from the use of the agent will depend upon the cause of the amenorrhea. In other words, amenorrhea must be looked upon as a symptom and not a disease, and treated accordingly. It may be either partial or absolute. When absolute the prog- nosis will in no small degree depend upon the presence or absence of the molimina. Obviously it would be improper to make an effort to restore the menstrual discharge by the aid of electricity when due to the presence of diseases like tuberculosis, chlorosis, Bright's disease, or anemia. However, there yet remains a class of cases constantly presenting themselves for treatment in which men- struation is absent or scant, because of deficient development of the sexual organs, or because of suppression due to nervous shock or change of residence, in which electricity is one of the most useful therapeutic agents. Girls who have never menstruated may have the function delayed, because of an entire absence of the uterus and ovaries. If a physical examination reveals this fact there will be but little use persevering in any kind of treatment, either local or general. On the other hand, if the development of these organs is rudimentary, and the symptoms of menstruation, except the flow, recur at regular intervals, the prospect of thus stimulating the undersized organs to perform their function is more encour- aging. There is still a further class of cases in which, according to Grandin, the application of electricity is most satisfactory. The amenorrhea in these cases is due to deficient nerve tone or force, and is typically "atonic" in character. This form of amenorrhea may be either primary or secondary, i. e., occurring in girls who have never menstruated, or in women who have menstruated, but from some cause, evidently not constitutional, the flow has gradually or suddenly ceased. In both instances ELECTRICITY IN GYNECOLOGY. 161 the normal stimulus seems to be absent, and the woman is ill because she does not menstruate. Sometimes the discharge seems to go toward the elaboration of adipose, and as a conse- quence she becomes corpulent concomitantly with the suppres- sion of the menses. At any rate if a patient thus affected can be made to menstruate, or if she is menstruating but scantily the discharge can be increased, she will be made well. The cases, then, in which electricity is most likely to prove useful may be enumerated as follows: First, where there is imperfect development of the sexual organs with molimina recurring at regular intervals. Second, where the suppression is the result of some cause which has been removed and menstru- ation is not restored because of the lack of what we call, for the want of a better name, sufficient "nerve tone." Imperfect development, malnutrition, and atony are the path- ological factors which are to be dealt with in the types of cases in the foregoing classification. The symptoms are variable as regards both intensity and character. In almost all instances, however, nervous depression is marked and hysterical manifes- tations frequently occur. Stimulation is, therefore, the object to be attained, and it is best attained by combined faradization and galvanization. The method of application will necessarily depend upon circumstances. Rockwell emphasizes the necessity of general faradization in all cases where malnutrition is marked, and central galvanization in patients hysterically inclined, or victims of insomnia. I have derived in these cases more good from gen- eral franklinization. Undoubtedly, the general use of electricity can often be advantageously combined with the local use of the agent in any of its forms; but in the cases under consideration local mechanical effects are required rather than general, hence local faradization is oftener indicated. This theory is in perfect harmony with other forms of treatment known to be useful. The introduction of the sound, the presence of a stem pessary within the uterine cavity and the insertion of tents have long been popular methods of stimulating the uterus in a purely me- chanical way, for the purpose of precipitating the menstrual flow. There are instances, however, where the local nutrition is at II 162 A TEXT-BOOK OF GYNECOLOGY. fault, and something more than mere mechanical stimulation is necessary. Patients thus affected are often robust and of full habit, and the application of faradism can be advantageously combined with galvanism. Again in those instances where the uterus and its appendages are imperfectly developed, both forms of electrization are called for. In young, unmarried girls the indirect method should be resorted to before direct application is made, though in all instances the direct method is the most useful and should be used, if necessary, before the treatment is abandoned. In the indirect method one pole is placed over the sacrum and the other over the lower part of the abdomen. When direct application is made, one pole is applied internally either through the vagina or the uterine cavity. Suitable elec- trodes are used for the internal pole. The external pole is placed over the lower abdominal region. If the faradic current is applied, it matters but little which pole is used internally. Inasmuch as the negative is slightly more irritating than the positive, the chances are that the results will be more decided if this be made the internal one. When the galvanic current is used, Rockwell, acting upon the theory that the positive exerts a more marked influence on unstriped muscular fibers, prefers it as the internal one. However, most authorities are agreed that the negative, because of its hemor- rhagic tendencies, should be made the internal one, unless seda- tion is required. Care must be taken not to use a current strong enough to produce caustic effects when the negative pole is inserted into the uterus. When the amenorrhea is absolute, the best time to make the applications is just before and during the molimina, for at this time nature is making an effort to perform a function which is held in abeyance. In no instance is entire reliance to be placed upon electricity, for other local measures, as well as constitu- tional ones, should be combined with its use. DYSMENORRHEA. Dysmenorrhea, like amenorrhea, is only a symptom, and may be due to one or more of several causes. The various lesions ELECTRICITY IN GYNECOLOGY. 163 (6 giving rise to painful menstruation are considered under the several affections of which it is a symptom. There yet remains a type of dysmenorrhea associated with that condition of the system which is designated under the head of amenorrhea as depressed nervous tone." There sometimes exists a condition of the uterus in which the organ, so far as can be ascertained by physical exploration, is perfectly healthy in every particular except that it is hyperesthetic. From some cause the uterus. is "irritable," and as a result the patient is a victim of dys- menorrhea. Such a patient is usually of a neuralgic tempera- ment, the symptoms of neuralgia presenting themselves upon the slightest exposure. It is this form of the complaint in which electricity is preëm- inently indicated. There is an entire absence of local disease, and the one symptom to be overcome may be defined by the term "hyperesthesia." Galvanism is, therefore, the most appli- cable in the vast majority of cases. The positive pole, being the sedative one, should be used inter- nally when the direct method is resorted to. Occasionally, and Rockwell particularly emphasizes this point, when the dysmen- orrhea is associated with amenorrhea, and especially if there is a possibility of the difficulty being due to pressure by exudates. upon nerve filaments, the negative pole should be the direct one. Dysmenorrhea may occur when the uterus is imperfectly developed, or when its diminished size is due to superinvolution. In instances of this kind stimulation as well as sedation is called for, and to cover this indication the faradic current must be utilized. In other words, we should direct our treatment to the undersized uterus. The necessity of so doing is referred to at this time as explanatory to the appended schema. In virgins, the abdomino-lumbar method may be tried before the direct is resorted to. However, in no instance should the treatment be abandoned as useless until the direct method has been faithfully persevered in. The application should be made at least twice a week during the entire intermenstrual period, and if possible every day during the week preceding the expected flow. Let it be remembered that in any form of dysmenorrhea 164 A TEXT-BOOK OF GYNECOLOGY. electricity is but an adjunct, though a very important one, to other methods of treatment. SUBINVOLUTION. By subinvolution is meant an abnormal condition of the uterus, the result of parturition, in which the organ is at first large, succulent, and congested, this condition passing in due time into induration and hyperplasia. The first stage is known as acute subinvolution, and the symptoms which are to serve as guides in the application of electricity are hypertrophy and concomitant hypersecretion. The second stage is characterized by condensation of tissue with atrophy, constituting that condition ordinarily defined as areolar hyperplasia. The indications for the use of electricity are very different in the two stages. In the first the object to be attained is stimulation and contraction; in the second, absorption of fibrous tissue and improved nutrition. Other methods of stimu- lating the uterus and causing it to empty itself of blood are the hot douche, intra-uterine applications, and the glycerin tampon. Electricity cannot supplant these several methods and should be considered simply as a supplement to them. In acute subinvo- lution the faradic current should be used for a few moments every day or every other day, followed by the customary glycerin or boro-glycerid tampon. If any inflammatory symp- toms exist the greatest care must be observed, particularly if applied by means of an intra-uterine electrode. By placing an intra-vaginal electrode in direct contact with the cervix with the external pole over the abdomen, the current is made to act upon both the uterus, and the vagina. This is desirable, for in most instances subinvolution of the uterus is associated with subinvolution of the vagina. In chronic subinvolution or areolar hyperplasia, the negative pole of the galvanic current must be used direct. SuperInvoluTION AND ATROPHY. These two conditions are the opposite of subinvolution, yet experience has demonstrated that in all three electricity is a valuable therapeutic agent. Rockwell observes that a still more ELECTRICITY IN GYNECOLOGY. 165 paradoxical feature of electricity is its power to relieve symp- toms of the most variable character, and its diametrically opposite action upon normal and abnormal tissue. In proof of this he cites the fact that it relieves both hyperesthesia and anesthesia ; that in one instance it will excite torpid excretory processes. and in another it will restrain this function when too active; and that while it will surprisingly develop normal tissue it will often readily reduce morbid growths. This seemingly paradoxical action is inexplicable to one unfamiliar with the law, similia. The object to be attained in superinvolution and atrophy is stimulation and improved nutrition; this is best accomplished by alternate faradization and galvanization. It must be admitted, however, that in superinvolution the results obtained by any method of treatment are not encouraging. Dr. Fordyce Barker is of the opinion that the prognosis depends upon the activity of ovulation. This is in keeping with what has already been said regarding the prognostic value of the molimina in amenor- rhea, for the molimina are in most instances undoubtedly due to ovulation. Dr. Barker gives as further symptoms of ovulation without menstruation pain and a sense of dragging in the pelvis, nausea and vomiting, intense headache with flushing of the face and congestion of the eyes. To this list Dr. Rockwell adds intense melancholia. So long as these symptoms are present, and in the absence of more effectual methods, we are justified in persevering with electricity. Grandin recommends the application of faradism just before and during the molimina, using utero-abdominal galvanization during the intervals. Inasmuch as amenorrhea is usually asso- ciated with an undersized uterus, the negative pole should be used direct in order to utilize its hemorrhagic effects. OVARALGIA. Neuralgic pains having their origin in or near the region of the ovaries, with an entire absence of appreciable lesion, consti- tute that condition known as ovaralgia. As in all neuralgic affections, the symptoms are chimerical and changeable. Hyper- esthesia and pain are the ones to be overcome, but in certain 166 A TEXT-BOOK OF GYNECOLOGY. cases faradization is more useful than galvanization. Rockwell, guided by his extensive experience in the treatment of external neuralgias, deduces his indications from the effects of pressure: If pressure relieves, faradism is the preferable form; if pressure intensifies, galvanism affords more speedy relief. Engelmann, on the other hand, bases his indications upon the duration of the difficulty, using the high tension faradic current in acute, and the galvanic current in chronic cases. CHRONIC OVARITIS. There is a variety of chronic ovaritis, characterized by con- gestion and enlargement of the organ without adhesions, in which electricity in the form of galvanism is the remedy par excellence. The congestion and irritation may result from many causes, but the most common one is sexual irregularity in some form. There is pain in one or both ovarian regions, which is worse before and during each menstrual period, and is aggra- vated by walking. The tendency of modern gynecology is to remove an ovary thus affected with but little ceremony. I am confident that the intelligent use of galvanism would make many such operations unnecessary. The hyperesthesia is best overcome by using the positive pole of the galvanic current direct. A vaginal electrode placed as close to the enlarged organ as possible, with the negative pole over the tender external area, is the most satisfactory way of administering it. If the indirect method is the one employed, the positive pole should be placed over the ovary and the negative over the sacrum. I do not think that a current of greater intensity than twenty-five milliampères is ever neces- sary. The séances should be repeated at least twice or three times a week. CHRONIC PELVIC INFLAMMATION. Under this head is included inflammation of any of the pelvic organs, but particularly the uterus and its annexa, together with their investing cellular tissue and the peritoneum. The pathology represents congestion and exudation, which, in turn, give rise to pain because of pressure, and to innumerable reflex symp- ELECTRICITY IN GYNECOLOGY. 167 toms. If such an exudation can be absorbed, and the pressure resulting therefrom relieved, the patient is made well. Even by combining all of the curative measures at our command, viz., the hot douche, the medicated tampon, the indicated remedy, and electricity, we shall often fail in accomplishing this. I nevertheless contend, that unless it is clearly evident pus has formed as a sequela of the inflammation, or unless other existing symptoms make delay hazardous, it is our duty to exhaust all reasonably safe methods before opening the abdomen. In the light of present data electricity promises much, and unless electro-puncture is resorted to, of which I do not approve, is perfectly free from danger. In almost all cases of chronic pelvic inflammation there is both local and general distress and, consequently, in the appli- cation of electricity three prominent indications are to be met, viz., sedation, absorption, and the relief of local congestion. When the local tenderness is very great, and particularly if menorrhagia is a prominent symptom, as it often is, the positive pole is the preferable one to use direct. After the local ten- derness and the hemorrhage have in a measure been controlled the negative pole should be used direct, because of its destructive tendencies. Intra-uterine applications must be made with much care, and intolerance of the uterus watched for. The applica- tions should be used from two to three times a week, the intensity of the current being governed, within certain limits, by the susceptibilities of the patient. UTERINE DISPLACEMENTS. Uterine displacements are not infrequently associated with, or the result of, those pathological changes which have already been considered in this chapter. When due to any of the causes enumerated the usefulness of electricity will depend upon the curability of the subinvolution, the absorption of adhesions, or the restitution of a relaxed pelvic floor. The kind of electricity and the method of application will, in such instances, necessarily depend upon the special lesion or lesions respon- sible for the displacement. There yet remains a certain number of cases of ante- or retro-flexion due to deficient muscular tone 168 A TEXT-BOOK OF GYNECOLOGY. in the region of the internal os, or to imperfect development. If the weak point in the uterus which is responsible for the dis- placement can be restored to a normal condition by the use of electricity, it is certainly more than has yet been accomplished with any other method of treatment. It is, however, admitted by Rockwell, who is an enthusiastic advocate of the agent in this field, that the results have not equaled the promises made by Tripier and some other specialists. Its usefulness probably depends upon the hyperemia and the con- traction of involuntary muscular fibers produced by the current. If this theory is correct it is desirable to localize its action as much as possible. To accomplish this the indirect pole should be placed in the rectum or in the bladder, depending upon the direc- tion of the displacement. The other electrode is introduced into the uterus. Faradization is called for in the majority of cases, but if local nutrition is much involved an occasional application of galvanism will hasten the cure. ENDOMETRITIS. Corporeal endometritis is usually associated with more or less metritis proper or with subinvolution, and the treatment is conducted upon the principles recommended for these affections. In cervical endometritis the usefulness of galvanism can hardly be over-estimated. Positive cauterization of the cervical endometrium will very often hasten the cure most surprisingly when the ordinary resources fail. The applications should be made not oftener than once a week and supplemented by the ordinary treatment for that condition. I use for the purpose Martin's platinum electrode and a current of not less than fifty milliampères. If there is much hypertrophy of tissue negative cauterization is preferable to positive. ELECTRICITY IN GYNECOLOGY. molimina (prognostic); NOSOLOGY. AMENORRHEA. PATHOLOGY. SYMPTOMS. INDICATIONS. TREATMENT. Imperfect development Presence or absence of Stimulation and improved Faradization.-General or local. (Rockwell.) and malnutrition; nutrition. Atony. Nervous depression. Galvanization.-Central or local, negative pole direct. Franklinization.-General. DYSMENORRHEA. Depressed nervous tone. Hyperesthesia; Neural Sedation. Occasional Sedation.-Galvanization, with positive pole gia; Absence of local disease. stimulation. direct. Stimulation.-Faradization, direct or indirect. SUBINVOLUTION. (ACUTE.) SUBINVOLUTION. (CHRONIC.) Congestion. Hypersecretion. Hyperplasia. Deficient secretion; Hystero-neuroses. SUPERINVOLUTION. Atrophy. Amenorrhea. OVARALGIA. No tissue change. Hyperesthesia. Sedation. CHRONIC OVARITIS. Congestion and inflam- Hyperesthesia. Sedation. mation. CHRONIC PELVIC INFLAMMATION, Pelvic congestion ; Exudation. Hyperesthesia; Pressure and reflex symptoms. Sedation; Absorption and ENDOMETRITIS. Congestion and Inflam- Hypersecretion and mation. hyperesthesia. UTERINE DIS- PLACEMENTS. Congestion; Inflamma- tion; Atony. Depend upon tissue changes. Stimulation and contrac-Stimulation.-Direct Faradization. tion. Absorption of fibrous tissue and improved nutrition. Stimulation and improved nutrition. relief of local conges- tion. Galvanization.-Positive pole direct. Galvanization.-Negative pole direct. Electro-puncture (Apostoli). Direct Faradization. Galvanization.-Negative pole direct. If pressure aggravates-Galvanization. If pressure ameliorates-Farad. (Rockwell). Galvanization.-Positive pole direct. Sedation.-Galvanization, positive pole direct. Absorption.-Galvan, negative pole direct. Electro-puncture (Apostoli). Sedation and relief of Galvanization (positive or negative pole di congestion. Depend upon tissue changes. Faradization. [rect). Congestion.-Galvanization and Faradization (positive pole direct). Inflammation.-Galvan. (positive pole direct). Atony.-Faradization. 169 CHAPTER XII. ANTISEPSIS IN GYNECOLOGY. With few notable exceptions all modern surgeons and gyne- cologists acknowledge the advantages of antisepsis. Those who do not, admit at least the utility and desirability of asepsis. There are but few even among the most ardent advocates of antisepsis who would resort to antiseptics if they thought perfect asepsis were possible without the use of germ destroying agents. There is no question that the indiscriminate use of antiseptics in the past has been attended with harm. This is especially true as regards the spray. And, too, it must be admitted that we are yet in ignorance regarding much that pertains to the field of bacteriology-a science as yet in its infancy. We cannot at the present time determine with absolute certainty whether, in a given case, the existing germs are the cause or the product of morbid processes. Personally, I am a believer in the so-called germ theory of disease. It affords to my mind the most rational explanation yet put forth of the transmission of many diseases. However, in a practical treatise of the nature of this work, an extended argument for the purpose of sustaining or disproving this theory would be inappropriate. I nevertheless desire to suggest the following:- 1. It is altogether probable that more perfect asepsis can be obtained by the use of antiseptics. I think that even the opponents of antisepsis will admit this; and unless antiseptics. are harmful, it seems to me wiser to be on the safe side and resort to their use. 2. Surgeons have now learned how and where to use the germ- destroying agents so as to avoid the evil effects which attended their early employment. The weakest solutions known to pos- sess germicidal properties have supplanted the stronger ones, and even the weaker solutions are not permitted to enter the 170 ANTISEPSIS IN GYNECOLOGY. 171 peritoneal cavity. Again, no antiseptic solution is left in any natural or artificial cavity of the body to be absorbed. If used within the uterus, its ready exit is assured either through a reflux catheter, or through a cervical canal thoroughly patulous; or if used to wash out a pelvic abscess, a drainage tube is intro- duced through which the excess of fluid can escape. In experimenting with antisepsis I have passed through three stages. When the so-called antiseptic craze first swept over the country I was fresh from college, and had hardly seen a wound of any kind heal by first intention. I was delighted with the early experiments made with carbolic acid and bichlorid of mercury. Unfortunately I soon met with several cases of car- bolic and mercuric poisoning, which led to my discarding for some years these agents entirely. I then studied antisepsis under some of the best-known Eastern specialists, and came to the conclusion that the accidents attending their use in my hands were largely due to faulty technique of application. During the first seven years of my service in the University of Michigan, I was compelled to do all of my hospital work in a building notoriously insanitary. As soon as I began to practise anti- sepsis in a fairly intelligent way my results were infinitely better; yet, in spite of the precautions taken, I had to do every now and then with suppurating wounds. Later I studied the technique of antisepsis in many of the European hospitals. Sir Joseph Lister's methods, as practised in King's College Hospital, disappointed me. I never have seen more untidy operating than witnessed in the clinic of the "father of antisepsis." This surgeon washes his wounds with a small quantity of bichlorid water, which he uses until it becomes absolutely thick with blood; yet, I am informed, his results are good. In nearly all of the London hospitals visited by me during the year of 1889 antisepsis was practised in this same haphazard manner. With the Continental surgeons, on the other hand, antisepsis has be- come almost a religion. As practised by such men as Leopold of Dresden, and Martin of Berlin, it means a great deal more than was comprehended by me before seeing these men operate. I now endeavor to carry out their methods as nearly as possible and am more than satisfied with the results obtained. Pus in 172 A TEXT-BOOK OF GYNECOLOGY. the healing of wounds is almost unknown to me. When suppu- ration does occur, I can usually trace the cause to some avoid- able source of infection-improperly prepared ligatures oftener than anything else. It is true that the success of men like Tait, Bantock, and a few others who ignore antiseptics, forces itself upon us. I have seen both of these men operate, Dr. Bantock many times. Tait does not even practise asepsis. I have seen him remove his finger from the vagina and thrust it into the abdominal cavity without even the formality of wiping it off. Bantock is as neat an opera- tor as ever picked up a knife. Everything about him is clean. In short, he practises asepsis. The great success of Tait can readily be accounted for by the genius of the man. He will make an abdominal section while the ordinary operator is rolling up his sleeves. His patients suffer the minimum of shock, for the intestines are hardly exposed. Both of these operators use drainage very much oftener than do the men who practise anti- sepsis. My own experience and observation, therefore, force upon me the advantages of antisepsis. I should like to discard the prac- tice if I could conscientiously do so, for, rigidly carried out, it means an endless amount of work and care. While such men as Tait and Bantock may dispense with antiseptics, it seems to me that, with few exceptions, the best results have been obtained by the surgeons who use them. The application of antisepsis in the practice of gynecology will be dealt with under the following heads:- I. The agents employed. 2. The operator and assistants. 3. The patient. 4. The operating room. 5. The operation. (a). The preparation and care of instruments; (b). The preparation and care of ligatures, sponges, and drainage tubes; (c). The use of the irrigator; (d). The dressings employed. 6. The after treatment. ANTISEPSIS IN GYNECOLOGY. 173 1. The Agents Employed.-For making antiseptic solutions. I use almost exclusively corrosive sublimate and carbolic acid. These can always be obtained, are inexpensive, and, above all, are probably the most trustworthy agents yet used. Creolin and beta-naphthol are highly recommended by some operators. Permanganate of potash is also used quite extensively for the purpose of disinfecting the hands. On the whole, it is better for the surgeon to adhere to those agents which he knows to be efficacious, and which he has learned to use intelligently. 2. The Operator and Assistants.-First of all, the operator, especially if doing abdominal surgery, should never come in contact with contagious or infectious diseases of any kind; nor should he or any of his assistants come from the dead room to the operating amphitheatre. Frequent washing of the entire body, including the head and beard, should be practised. In the event of contact with any of the contagious or infectious diseases, corrosive sublimate (1:2000) should be used to cleanse the person. The clothing should be absolutely free from infec- tion of any kind, and, during the operation, protected with an operating gown and apron extending from the neck to the feet. The sleeves should be rolled above the elbows, and the nails scrupulously cleaned. The hands and arms are next thoroughly washed with soap and water, and then for five minutes in a I: 1000 bichlorid solution.* Kelly of Baltimore, follows this by immersing the hands in a solution of permanganate of potash (4: 1000), after which they are washed in a concentrated solution of oxalic acid. This is an extreme measure, and one which I do not resort to unless there is clinging to the hands an odor resulting from contact with fetid discharge or substance—can- cerous discharge, fecal matter, etc. The operator should refrain from operating if he has a suppurating wound of any kind on his hands. 3. The Patient.-The necessary preparation of the patient will depend somewhat upon the nature of the operation. For the ordinary operations upon and through the genital tract the * I have found Johnston's Ethereal Antiseptic Soap, manufactured by Parke, Davis & Co., exceedingly useful for this purpose. 174 A TEXT-BOOK OF GYNECOLOGY. patient should take a bath the night preceding, or the morning of the operation. The bowels should be emptied by an enema not later than two hours before the anesthetic is given (if the enema is administered later than this water is retained and will be expelled during the operation). In surgical work of the rectum it is a good plan to follow the enema with a saturated solution of boracic acid (30: 1000). The patient should have the vagina washed with a large hot bichlorid douche (1: 3000) before being placed upon the table. It is also well to have the external genitalia scrubbed with soap and water and an antiseptic pad placed over them. After the patient is anesthetized the mons veneris and external genitalia are again washed with soap and water, shaved, and finally douched with a 1:2000 bichlorid solution. Next the vagina, by the aid of the fingers, is thoroughly washed with the same solution. If the operation is upon the cervix or within the uterine cavity I first remove as much of the discharge as is possible with absorbent cotton, and then pass into the cervix an applicator dipped in impure carbolic acid. In abdominal cases the bowels should be emptied the day before the operation with a cathartic, and the morning of the operation with an enema. The skin should be gotten in good shape by frequent bathing-the last bath being a 1:2000 bi- chlorid solution. A compress wrung from a 1: 1000 bichlorid solution is applied to the lower abdominal and genital regions for twenty-four hours previously to the operation. The vagina is prepared with the same care as in operations confined to this canal. After the last douche it is packed with iodoform gauze, which is to be left in until the patient is anesthetized. The pubes should be shaved on the day preceding the operation. When everything is in readiness to operate, the compress and tampon are removed, the field of operation again washed with soap and water, and finally with a 1:1000 bichlorid solution. Especial care is to be observed in cleaning the umbilicus, in order to dislodge all hidden accumulations. Next, sterilized towels are wetted in a 1:2000 bichlorid solution and placed in such a way as to cover the entire surface of the abdomen (except the immediate site of the incision), the genital region, ANTISEPSIS IN GYNECOLOGY. 175 and the upper thighs. All instruments, ligatures, etc., are thus prevented from coming in contact with any portion of the integument. 4. The Operating Room.-In the construction of hospitals the operating room should be as far removed as it can be from the general wards, or from other possible sources of infection. It should be so constructed as to be easily cleaned, and there should be no unnecessary angles or woodwork upon which dust or germs can lodge. The furniture should be scanty and exclusively of metal or glass. A sky-light, especially in abdom- inal work, is most desirable. Antiseptics of variable strength, and sterilized water, should be conveniently at hand. In operative work outside of the hospital all mattings, cur- tains, tapestry, and unnecessary furniture should be removed. A room should be selected possessing a good light-preferably with a southern exposure. Inquiry should be made as to whether the room has been recently occupied by contagious or infectious cases. If an abdominal section is to be made old paper should be removed, the walls washed with a 50: 1000 carbolic solution, and followed by sulphur disinfection. The room ought to be gotten ready at least forty-eight hours before the operation. The Operation.-Various methods having for their object the disinfection of instruments are in vogue. I rely almost entirely upon boiling in sterilized water. The antiseptic agents are so injurious to all metal instruments that I have discarded them for this purpose. Heat maintained at a proper temper- ature and for a sufficient length of time is, to my mind, the best of all antiseptics. In the first place I obtain instruments of the simplest construction, which can be taken apart and thoroughly cleaned. The handles should be of metal so that the boiling will not damage them. After an operation all instruments are scrupulously cleaned, boiled, and dried. Before being used again they are boiled for twenty minutes, removed from the boiling water and immersed in sterilized water contained in operating trays. This method possesses all the elements of sim- plicity and can be applied under all circumstances. In hospital work a sterilizing oven may be substituted for the boiling process. All towels used about the operation should be • 176 A TEXT-BOOK OF GYNECOLOGY. thoroughly sterilized by being subjected either to dry heat or to boiling. The ligatures most generally used are silk, silkworm gut, and silver wire. The flat plaited silk is preferable to the twisted. It comes in six sizes and should be boiled for an hour in a 50:1000 carbolic solution. It should be kept in the same solution in some convenient ligature holder admitting of its withdrawal without contamination. Silkworm gut may be prepared and kept in the same way. Kocher's method of preparing catgut, as given by Gerster,* is as follows: "Immerse catgut for twenty-four hours in good oil of juniper (ol. juniperi baccarum, oil of the berry, not the oil gained from the wood); transfer into and preserve in absolute alcohol until used. Alcohol keeps catgut hard and firm, yet flexible. Carbolic acid or corrosive sublimate will make it brittle and weak. When it is desirable to prevent too early absorption, as, for instance, in intestinal sutures, a hardening process should be added to the disinfection. The catgut should be washed in alcohol, then placed in a quart of a five per cent. solution of carbolic acid con- taining thirty grains of bichromate of potash. Forty-eight hours immersion will produce catgut that will resist the action of living tissue for a week or longer. Large- sized catgut needs a longer immersion." I am using catgut more and more in plastic work as time goes on. If properly prepared and perfectly aseptic it is one of the best of ligatures, possessing the great advantage of being absorbed. It is the one suture, therefore, which can be buried in the tissues. Unfortunately it is easily contaminated and its use requires great care. The only preparation required in using silver wire is heat sterilization. I have for some years resorted to Borham's method of cleaning sponges. I quote from J. Greig Smith †: "The sponges are first repeatedly washed in water for the purpose of removing all sand and dirt. This requires several days' time. They are next soaked for three or four minutes in a one per cent. solution of potassium permanganate. The per- manganate is then washed out by repeated squeezings in fresh water. Next, they are placed in a solution of sodium hyposulphite, of the strength of half a pound of the salt to the gallon of water, to which an ounce of oxalic acid has been added. Finally, they are washed in cold water, dipped in carbolic solution, and dried.” * “ Aseptic and Antiseptic Surgery." † Abdominal Surgery, 1887, p. 60. ANTISEPSIS IN GYNECOLOGY. 177 After this preparation they should be kept in a clean paper bag or a closed glass jar until used. I prefer to purchase inexpensive sponges and use them but once. It is entirely possible, however, unless they have come in contact with septic matter, to clean them after being used so as to make them again perfectly aseptic. They should be first washed in plain water, so as to remove as much of the blood and filth as possible. They are next placed in the soda solution, which will dissolve the blood and fibrin. This should be changed several times, and the sponges should be repeatedly washed and squeezed in it. Finally, they are cleansed in pure water, "dipped in carbolic solution, squeezed and dried, and kept in a dry place till further use." After septic operations, it is best to destroy them. Owing to the danger of sponge contamination some operators have abandoned them entirely, substituting for them compress sponges. These are prepared as follows: "A piece of gauze is folded so as to form a square of thirty centimeters (10: 12 inches), composed of eight thicknesses of cloth. These compresses are fastened at several points along each border. Then they are boiled for two hours or less, either in a carbolic solution (50: 1000), or in bichlorid (1:1000). Finally, they are pre- served in a fresh solution of the same, which should be changed every week. Before using they should be carefully washed in sterilized water and wrung as dry as possible. They then con- stitute a powerful absorbing agent, which can be quickly given any form or dimension, can be wrapped around the finger in penetrating into cavities or interstices, when exposing the intes- tines, which, in a word, offers advantages much superior to those of sponges."-Pozzi. I have often used the compress sponges in abdominal work instead of the large flat sponges, which are very expensive. When smaller sponges will answer the purpose, I prefer them to the compresses. Rubber drainage tubes are not often required in gynecological surgery. Soft, pliable rubber tubing, of black material and of proper size, should be selected. This is cut into suitable lengths, which are placed in a wide-mouthed bottle and immersed in a 12 178 A TEXT-BOOK OF GYNECOLOGY. < five per cent. carbolic solution. The solution should be renewed from time to time. For abdominal drainage, glass tubes are used oftener than any other form of drainage. The antiseptic solutions do not injure the glass, and they can be boiled for twenty minutes either in a five per cent. carbolic solution or a 1: 1000 sublimate solution. They should be rinsed in sterilized water before being placed within the peritoneal cavity. Another form of intra-abdominal drainage which has become very popular during the last two years is so-called tamponnement of the peritoneum, first suggested by Mikulicz.* The object of tamponnement is, primarily, to isolate the portion of the perito- neum tamponed from the rest of the peritoneal cavity, and, secondarily, to afford drainage by capillary attraction. Mikulicz first places at the bottom of the cavity to be tamponed a purse of iodoform gauze, to the middle of which is attached an anti- septic silk ligature (Fig. 57). Strips of gauze are now packed into this purse in such a way as to produce sufficient pressure to control oozing. The superior ends project from the neck of the purse at the lower extremity of the abdominal wound. I have often used gauze packing within the abdominal cavity without the precaution of first introducing the purse. It is, how- ever, more difficult and painful to remove one continuous long strip than several shorter ones. The tampon may be left within the peritoneal cavity for from one to five days. In one In one case I found it necessary to use nearly four yards of gauze (one yard wide) in order to prevent immediate death from hemorrhage. It was partly removed on the third day, but it was not all withdrawn until the end of the seventh, and was then perfectly sweet. In controlling hemor- rhage from large oozing surfaces I know of nothing more satis- factory in abdominal surgery than gauze packing. If deemed best a glass drainage tube may be introduced into the center of the tamponnement, though by placing a pad of gauze over the * The reader is referred to the Annales de Gynécologie et d'Obstetrique, 1890, for a most exhaustive résumé on the subject of abdominal drainage by Saenger of Leipzig. ANTISEPSIS IN GYNECOLOGY. 179 ends projecting from the abdominal cavity capillary drainage is usually sufficient. In all operations upon the cervix, vagina, perineum, bladder, or rectum, and in vaginal hysterectomy, the irrigator is invaluable. Irrigation can be practised either in the lithotomy or Sims FIG. 57. b/ a PETHAL TAMPONNEMENT OF THE PERITONEUM.-Pozzi. a a. Purse of iodoform gauze; b. Silk thread; c c. Strips of gauze. posture. Until I saw the German operators work I used the Sims posture for all work upon the cervix and vagina. With the patient upon her side it is exceedingly difficult, in using irrigation, to keep from wetting her. I now resort to the lithotomy position in all operations within the vagina, except those for vesico-vaginal fistula. By using Frisch's modification 180 A TEXT-BOOK OF GYNECOLOGY. of Simon's specula the irrigating tube can be attached to the upper blade, at the tip of which is an opening through which the water can pass. The size of the stream is controlled by a stop-cock near the attachment of the tube. Either the bichlorid (1 : 5000) or the carbolic (10:1000) solu tion may be used for irrigation. The parts are kept constantly bathed in one of these fluids, thus preventing wound infection during the operation, and making sponging unnecessary. using the buried catgut suture irrigation should be constant. In Gynecological dressings, outside of abdominal work, are of the simplest character. After plastic operations in and about the vagina and perineum it is my practice to sponge the parts dry and sprinkle iodoform over them. A strip of iodoform or bichlorid gauze is then packed into the vagina and about the cervix for the purpose of sustaining the parts should the patient vomit. This is removed in from five to ten hours. Over the vulva is placed an antiseptic pad. * When the wound is closed by the buried catgut suture, it is recommended by Marcy of Boston, that it be hermetically sealed with iodoform collodion. In laparotomy, after the abdomen is closed by whatever method adopted, the wound is washed with a 1: 2000 sublimate solution, dried, sprinkled with iodoform, protected with a narrow strip of sterilized oiled silk, and covered with iodoform or subli- mate gauze, over which is placed several layers of sterilized absorbent cotton. The dressings are held in place by a sterilized * Gauze may be prepared as follows:- Bichlorid Gauze.-Wide mesh cheese-cloth cut into convenient pieces. Then soak for twenty four hours in a solution of soda (one pound to twenty yards of gauze, and sufficient boiling water to cover). Wring; wash in cold water. Then for forty- eight hours in bichlorid 1: 1000. Wring; dry; fold. Carbolized Gauze.—A five per cent. carbolic solution is used in place of the bichlorid. Iodoform Gauze.-Take Iodoform, Glycerin, Bichlorid sol. (I : 1000), • • D 3 ss 3ss • qt. j. In this mixture soak ten yards of bichlorid gauze prepared as above, wring and then fold.-Mundė. ANTISEPSIS IN GYNECOLOGY. 181 binder. Should a drainage tube be introduced its mouth is protected by a sponge wrung from a I: 2000 sublimate solution surrounded by a sterilized rubber dam. 6. The After Treatment. For much pertaining to the after treatment the surgeon will have to rely upon the nurse and general attendants. Consequently, unless he can impress upon them the importance of antisepsis, all of his precautions will have been in vain. I know of nothing more exasperating than a slovenly nurse, one who is not sufficiently intelligent, or, if she is, will not follow the surgeon's directions. In operating outside of the hospital it is, therefore, wise to have printed instructions with which the nurse can jog her memory after the surgeon's departure. * In all plastic operations I permit the patient to urinate spon- taneously if she can do so. After urination the nurse is instructed to use a small 1: 3000 cleansing douche of bichlorid. I have every reason to feel satisfied with this treatment, for failure in primary union is almost unknown to me. If the patient cannot urinate naturally the catheter is used, care being observed to keep the finger over the mouth of the instrument while it is being withdrawn, so that not even a few drops of urine will come in contact with the wound. When the catheter is used no injections are necessary unless there is a contaminat- ing discharge from the upper genital tract. It is hardly neces- sary to add that, when the douche is used, each patient should have a separate nozzle, and this should be frequently cleaned. Antiseptic precautions cannot be too rigorously carried out in the use of the catheter. I have discarded absolutely the old silver female catheter, and very rarely use the rubber instrument. In their stead I use Kustner's glass catheter made by George Tiemann & Co. They are inexpensive, sufficiently strong to insure against breakage, and can be boiled and cleaned repeatedly. The soft rubber instrument cannot be used with safety more than six or eight times, and cannot be kept aseptic. The nurse is instructed to boil the glass instrument each time after its with- drawal. It is then kept in a carbolized solution until again * I will not even except lacerations of the perineum closed immediately after labor. 182 A TEXT-BOOK OF GYNECOLOGY. required, when it is rinsed in water and smeared with carbolized vaseline before being introduced.* Always before its introduc- tion the vestibule should be washed with an antiseptic fluid of some kind. Before observing these somewhat extreme measures urethral and vesical irritation, and even inflammation, were of frequent occurrence in my hand. Now I rarely if ever have to contend with any trouble of the kind. In laparotomy, where the drainage tube is used, the syringe for drawing off the fluid should be constantly immersed in a a 50: 1000 carbolic solution. The sponge over the mouth of the tube should be frequently changed and care observed not to leave the opening unprotected any longer than is absolutely necessary. Of course previously to each dressing the hands of the attendant should be washed in an antiseptic solution. ANTISEPSIS IN ORDINARY GYNECOLOGICAL EXAMINATIONS. In ordinary gynecological examinations the danger of possible infection should always be borne in mind. There is no ques- tion that the various specific diseases are frequently conveyed through unclean instruments. When the uterine cavity is explored, precaution is especially necessary. The hands should always be thoroughly cleaned in a carbolic solution before and after each examination. The bichlorid solution for constant washing of the hands is too irritating. The examining instru- ments-specula, probes, tenacula, etc.—ought to be frequently boiled and kept bright by the use of sapolio. They are to be kept immersed in a carbolic solution during the examination. Each time after using they should be washed in boiling water and again immersed in the carbolic solution. I use the carbolic solution here because it is impracticable to boil the instruments after each examination. It will, of course, tarnish them some- what, but the cost of replating is slight, and a physician has no right to subject his patient to the slightest danger of infection. The old-fashioned bi- and tri-valve specula are harbingers of filth and germs. It was this fact which led me to devise the * Unless care be observed septic matter may be transmitted through the vaseline. ANTISEPSIS IN GYNECOLOGY. 183 instrument shown in Fig. 27. The blades can be quickly separated and the joints gotten at with perfect ease. It is wise to dip the uterine sound and probe into impure car- bolic acid before they are inserted. If recently used in a sus- pected case of gonorrheal endometritis, a still safer procedure is to heat them over a spirit lamp. In the application of electricity through the genital tract, the same care as regards cleanliness must be observed. When the intra-uterine electrode is used, it should be introduced through a speculum, so that the vagina and cervix can be first washed with an antiseptic solution. The electrodes insulated with either hard or soft rubber cannot be sterilized by heat, so that unusual precaution is necessary in washing them. In cleaning the spiral intra-uterine platinum electrode of Martin, a good brush is necessary in order to dislodge the secretions which find their way between the wires of the spiral. CHAPTER XIII. THE HYSTERO-NEUROSES: HYSTERIA. DEFINITION. The term hystero-neuroses, in its restricted sense, implies the uterine origin of symptoms manifesting themselves in organs remote from the uterus, without structural change in such organs, being the direct result of reflex nervous influence starting from the uterus. By common usage reflex symptoms of ovarian origin are also defined as hystero-neuroses, although the term oophoro-neuroses would more correctly indicate their origin. If it be true that disorders of the rectum, or of any of the pelvic organs, produce reflex symptoms-and there is abun- dance of clinical evidence to show that they do-it is obvious that the foregoing definition is too restricted. The word "hysteria" was used by the early writers to define the multi- tudinous phenomena now classified under that name, because of the erroneous idea that the womb (úσtépa) moved about to various parts of the body and so caused the local symptoms. (Gowers.)* The adjective “hystero" is derived from the same Greek word, and likewise erroneously suggests the uterine origin of a class of symptoms to which the term pelvic neuroses would be more literally correct, and infinitely more scientific. While, therefore, it is the mission of the gynecologist to treat any lesion found within the female pelvis, it seems wiser to adhere to the name (hystero-neuroses) which usage has made popular. The term hysteria should be restricted to the general neuroses characterized particularly by psychical as well as secretory, vaso- *"Plato says that the uterus, being an animal desirous of generation, if unfruitful for a long time, becomes indignant, and wandering all over the body stops the passages of the spirits and the respiration, occasioning thus the most extreme anxiety and all sorts of diseases."—Jenks. 184 THE HYSTERO-NEUROSES: HYSTERIA. 185 motor and reflex derangements. It is probable that hysteria belongs among the cerebro-spinal affections. It is by no means limited to the female sex, although it is much more commonly met with in women than in men. Therefore, according to the definitions given, hysteria does not necessarily have its origin in disordered uterine or ovarian function, while the hystero- neuroses always have. Inasmuch as the pathology of both affec- tions is too occult and subtle to be perfectly understood in the present state of neurological science; and inasmuch as hysteria, as it manifests itself in women, is usually associated with utero- ovarian disease, a clinical distinction is often impossible, and indeed, unnecesary. It is only important to remember that in hysteria there may be actual disease of the nerve centers, while in the hystero-neuroses no such disease is present. In both, however, the nervous centers are unduly impressionable, and I therefore deem it wise to study the two conditions under the same clinical head. By so doing I shall at least avoid uncertain and profitless discussion. Neurasthenia or nervous prostration is likewise frequently associated with the hystero-neuroses. GENERAL CONSIDERATIONS. The so-called neuroses are but beginning to receive the attention which, from their importance, they deserve. Those of the genital system constitute but a single group of that varied conglomeration of symptoms which may have their origin in any organ of the body. Flint has called attention to the cardiac neuroses, and to Dr. Pratt we owe much for his work in the rectal reflexes. The nasal and bronchial neuroses, as well as the ocular, are now receiving due attention. It is well known that, under favorable conditions, the slightest derangement or modification of function in a sensitive organ, so slight as to attract no attention to that organ, may, to use the simile of a well-known writer, cause distant organs to respond most violently-as the alarm-gong responds to the tap of a distant button. The sympathy existing between the stomach and the brain is well known, and the one will quickly respond to any disturbance 186 A TEXT-BOOK OF GYNECOLOGY. of the other. It may be impossible to overcome reflex asthma and so called hay fever without directing attention to the hyper- trophied posterior nares or the nasal mucous membrane. We are told by the oculist that certain obscure nervous symptoms and even epilepsy may be due to errors of refraction. All gynecologists know that an anal fissure will cause not only exquisite pain at the seat of the lesion, but may disturb the whole vaso-motor system, giving rise to the most irregular distribution of blood in various parts of the body. I myself have seen an obstinate reflex paraplegia disappear only after curing a urethral fissure. I cite these well-known clinical facts simply to show that the genital sphere is only one of many capable of impressing the organism most profoundly in a reflex way; and the absolute necessity of studying the organism as a whole in looking for reflex causes. Neurologists and gynecologists, unfortunately, do not agree. as to the importance of the hystero-neuroses. I am confident, however, that the former are often in error in ignoring pelvic symptoms as causative factors. Careful observation will, I believe, demonstrate to the neurologist as well as to the general practitioner, that uterine disease frequently exists, even though the ordinary symptoms of such disease are wanting. A thorough study of all of the neuroses tends to broaden the specialist, no matter in what department of scientific medicine he may be engaged, for it leads him into the great domain of anatomy and physiology. FORMS OF HYSTERO-NEUROSES. For convenience of study, the hystero-neuroses may be classi- fied as- 1. Physiological, giving rise to reflex symptoms owing to increased functional activity, as during menstruation, pregnancy, and during puberty and the menopause. 2. Pathological, giving rise to reflex symptoms having their origin in some pathological change of the female sexual apparatus. (Engelmann.) This classification is not strictly correct. The term physio- logical neurosis is paradoxical, for, if a function is perfectly THE HYSTERO-NEUROSES: HYSTERIA. 187 physiological, there should be no disturbance suggesting such a term. The fact remains, nevertheless, that there are few women who do not suffer some inconvenience during the several crises. characterized by physiological congestion, and the classification at least facilitates understanding. THE PHYSIOLOGICAL HYSTEro-Neuroses. (a) The Hystero-Neuroses of Puberty. The function of menstruation in most instances gives rise to more or less dis- tress, and to a feeling of uneasiness within the pelvis, which is still without the domain of actual or discoverable disease. This is especially so before the function is regularly established. In a girl whose nervous centers are unduly impressionable, reflex disturbances are common. Headache, nausea and vomiting, local spasms, neuralgia, choreic manifestations, and actual hys- teria, are not infrequent symptoms. (b) The Hystero-Neuroses of Menstruation.-The nervous symptoms of menstruation often persist during the entire men- strual life. The congestion causes an increased nervous excita- bility, and the neurosis, which may have subsided during the intermenstrual period, recurs. Here again it is probable that a pathological condition so insignificant as to cause no trouble without the super-added menstrual congestion is, in at least the majority of instances, responsible for the neurosis occurring at this time. Menstrual neuroses are not limited to the actual period of the flow, often occurring some days before the san- guineous discharge takes place, and persisting for several days after it ceases. (c) The Climacteric Hystero-Neuroses.-The neuroses occurring at this period are, in nearly every case, traceable to pathological lesions. And yet symptoms often occur during the change of life, as during puberty, which are without the domain of actual disease. There are few women who complete this period without suffering more or less from flushes, nervous irritability, faintness, headache, etc. (d) The Hystero-Neuroses of Pregnancy.-The uterus and all of the pelvic organs during the pregnant state are char- 188 A TEXT-BOOK OF GYNECOLOGY. acterized by increased functional activity. Neuroses are frequently excited by these physiological changes, and often do not cease until the uterine cavity is evacuated and the conges- tion terminated. The stomach is usually the first organ involved in a reflex way, as a result of conception, and so common a symptom of pregnancy is nausea and vomiting that it constitutes one of its classical signs. The head, the eyes, the salivary glands, the thyroid, the bowels-indeed every part, and every function. of the body may be disturbed as a result of conception. Let it be remembered that the existence of physiological neuroses is in perfect harmony with the theory already set forth,* to the effect that either hyperemia or hyperesthesia of the pelvic organs is essential for the production of reflex symptoms having their origin within the pelvis. With the data now in our posses- sion, we are justified in drawing a line between physiological con- gestion and hyperemia and pathological. Physiological congestion may affect the female organism either almost imperceptibly or very profoundly, depending upon the impressionability of the nervous system; the same is true of pathological congestion and lesions. It is probable that the degree of local hyperesthesia is likewise governed by the state of the nervous system. This explanation is in perfect accord with clinical evidence, and will account for the contradictory theories held by different men, equally eminent, regarding the importance of local lesions as symptom-producing factors. The gynecologist knows very well that the most serious or fatal local lesion may run its course without exciting any reflex symptoms, whereas in another patient, differently con- stituted, the slightest local rent may make her life miserable. Types of temperament are equally distinguishable during child- hood. The eruption of the teeth will occur in one child without the slightest disturbance, while in another this physiological process will precipitate the most violent convulsions; or, pre- putial smegma will cause no nervous irritation whatever in one instance, while in another its presence may cause convulsions, and even arrest of development. * v. Chapter VIII. THE HYSTERO-NEUROSES: HYSTERIA. 189 DIAGNOSIS. The most weighty diagnostic evidence in determining the existence of a neurosis is the absence of structural changes in the organ or part involved. Unfortunately, even learned and experienced diagnosticians cannot, for instance, always differen- tiate between vaso-motor disturbance and slight inflammation, or between a reflex epilepsy and one due to organic disease of the nerve-centers. Engelmann has so admirably summarized the essential diagnostic points that I quote from him in full :— 1. A neurosis is probable, and may be suspected- * (a) By the existence of violent symptoms without correspond- ing pathological changes or febrile reaction. (b) By the existence of lesions, uterine or ovarian. (c) By the failure of proper remedies to afford relief. (d) By the aggravation of symptoms in the affected organ corresponding to exacerbation of uterine diseases. 2 A neurosis is proved- (a) If symptoms are not aggravated by causes which are known to aggravate existing pathological changes in the organ affected. Thus, the use of indigestible food will not aggravate a gastric neurosis, whilst the most violent symptoms may appear in response to a diet which would seem indicated in disease proper. (b) If the symptoms are aggravated by causes from which exacerbation of uterine disease may be suspected. (c) Improvement of symptoms upon treatment of uterine or ovarian disease regardless of any interference with the organ in which the neurosis appears. (d) By a cessation of symptoms upon improvement or cure of uterine disease. It is necessary to eliminate from the category of neuroses those manifestations of pain due to pressure. Pelvic tumors, inflammatory exudates, or a pregnant uterus may cause most persistent and agonizing pain in the lower extremities by imping- ing upon the nerves within the pelvis. Disordered defecation * American System of Gynecology, Vol. II, p. 77. 190 A TEXT-BOOK OF GYNECOLOGY. and micturition may likewise result from an increased pressure exerted by the uterus during menstruation. These are not reflex symptoms and should not, therefore, be confounded with the neuroses. PROGNOSIS. In considering the prospect of recovery from the hystero- neuroses and hysteria it is necessary to study the duration of the symptoms, the nature of the lesion to which they are due, and the previous neurotic history. The severity of the symptoms is not a safe criterion upon which to base a prognosis. The slight psychical disturbances which are permanent and per- sistent in character are of much more serious import than violent and transitory symptoms. It must not be forgotten, however, that ineffaceable traces of psychical weakness are apt to follow in the train of even slight and temporary attacks of insanity. With the exception of the neuroses of the eye, nearly if not all of the reflex symptoms originating within the pelvis disappear upon removing the cause of such symptoms. Functional changes of that organ may be, and, unfortunately, are frequently perpetuated if the local disease persist for any length of time. So, too, if other organs of the body suffer in a reflex way for years, there is liable to be a certain trace of weakness left behind after the more distressing symptoms have vanished. With the foregoing exceptions the prognosis of the hystero- neuroses is good. But the persistency of the symptoms after the cause is removed is most variable, and the practitioner should be cautious not to promise immediate relief in all instances. I have many times seen a most distressing headache relieved almost instantly by correcting a displaced uterus, or by a simple application to an abraded cervix. I have seen a reflex asthma, which had followed almost every defecation for years, disappear upon removing a prolapsed ovary. I have on many occasions witnessed the disappearance of various types of psychoses, and of pain in various organs and parts of the body soon after the re- moval of cicatricial tissue from, and the closure of, cervical rents. I have frequently seen cold hands and cold feet become warm almost immediately after divulsing the rectum. Immediate THE HYSTERO-NEUROSES: HYSTERIA. 191 results of this kind will not infrequently follow operations and local treatment, but oftener the improvement is gradual and slow. This is especially true when physical debility has been induced by depraved nutrition incident to reflex disturbance; for then reinvigoration depends upon the proper performance of the digestive function. So, too, time is required if there is anemia due to excessive uterine hemorrhage, for which the ovaries are removed or the cervical rent is closed; or if there is a badly subinvoluted uterus requiring months after oper- ating before it returns to its normal size. Indeed, it is not uncom- mon for the patient to feel worse for two or three months after a serious operation, and her symptoms do not begin to disappear until the system fully reacts from the shock of the operation. As soon as the marked irritation of the ganglia implicated begins to disappear improvement sets in, and often of the most decided character. What the patient describes as "nervous ten- sion" vanishes; her expression changes from that of dejection to one of hopefulness; the dark rings surrounding the eyes disap- pear, as does the sallowness of the skin. She no longer suffers from distress in the affected organ or organs, and her nutrition improves simultaneously with the improvement of digestion and assimilation. It must not be forgotten, however, that when psychical symptoms predominate there is always more or less danger of relapse. This is especially true if the patient is subjected to ill-directed sympathy bestowed by over-zealous friends. From this it may be necessary to protect her by an entire change of environment. CHAPTER XIV. THE HYSTERO-NEUROSES: HYSTERIA (Continued.) SYMPTOMATOLOGY. A convenient classification of the hystero-neuroses is the following:- 1. Disorders of Sensibility. (a) Hyperesthesia; (b) Anesthesia. 2. Alterations of Motility. (a) Clonic and tonic spasms; (b) Paralyses. 3. Circulatory Disturbances. (a) Central or cardiac; (6) Peripheral or vascular. 4. Anomalies of secretion and excretion. 5. Disorders of respiration. 6. Disorders of the gastro-intestinal canal. 7. Disorders of the Skin. (Dermatoses.) 8. Glandular disturbances. 9. Disturbances of the nervous system. (a) General; (6) Psychical. DISORDERS OF SENSIBILITY. (a) Hyperesthesia.-Hyperesthesia may be either general or local, but it is rarely if ever absent in some form. There is apt to be an exaggerated sensible irritability, so that sensory stimuli increase various kinds of pleasure and aversion; or, if the hyper- esthesia be greatly exaggerated, stimulation of the senses may produce pain instead of pleasure. Increased sensible irritability is often perverted, so that stimuli which would excite in the well actual disgust become a source 192 THE HYSTERO-NEUROSES: HYSTERIA. 193 of pleasure to the hystero-neurotic; or the highest degree of discomfort may be produced by agencies which, in the well, give rise to pleasure. There may also be what Jolly terms a psychical hyperesthesia, characterized by "exaggerated sensations of de- sires and repugnance.” The senses of sight and hearing are often extremely hyperes- thetic. When the eye is involved patients cannot tolerate a bright light, and in the worst cases they are compelled to confine themselves to a darkened room. There may be subjective phenomena of flashes, sparks, or phantasms, but these symptoms are oftener associated with hysteria or ecstasy due to other causes than utero-ovarian disease. Nevertheless, hyperesthesia is probably present whenever hallucinations of vision occur. Excitation of the sense of hearing gives rise to greater acute- ness of this faculty, so that in the worst cases slight noises are not only distressing but painful. Ringing, blowing, roaring, etc., frequently occur as subjective phenomena. From a patient whose greatest distress was a tinnitus aurium, for which she had been examined by my colleague, Prof. D. A. MacLachlan, who found no local ear disease, I removed an incredible amount of cicatricial tissue from the cervix, which entirely relieved the tinnitus. Hallucinations of hearing are rarer than visionary hallucinations, and when present suggest the possibility of permanent mental aberration. Perverted smell and taste occur with especial frequency. Odors which ordinarily are pleasant become repugnant and the most delicious flavors may excite nothing but disgust. On the other hand, unpleasant and disagreeable substances which are repellent to the healthy may be sought for. Cravings for chalk, dust, coal, and like materials are not uncommon. The acuteness of smell is sometimes remarkable. One patient of mine could detect the odor of musk contained in a medium trituration and carried within a pocket case immediately upon my entering her chamber. A case is recorded by Amann of a woman who could distinguish persons by smell. The sense of touch is rarely exaggerated, though it may be. The refinement of touch varies greatly in different people who are in every way healthy. The" muscle reader" possesses such 13 194 A TEXT-BOOK OF GYNECOLOGY. refinement to an extreme degree. If this same exalted sensi- bility implicates any of the sensory regions, cutaneous hyperes- thesia of that region is the result. It may be limited to a small portion of the body or it may be general. The hyperesthesia often involves the deeper structures, impli- cating muscles, fascia, and joints. Actual disease is so closely simulated as to make it oftentimes exceedingly difficult to determine the spurious from the genuine. The so-called hys- terical joint is not uncommon, and frequently has its origin within the pelvis. Mitchell, Brodie, Pajet, and Hilton have placed on record many such cases. If there has been real injury to the joint, with hysterical phenomena either preceding or following such injury, the problem is often exasperatingly perplexing. With the purely hysterical joint there is pain without heat or swelling; again, forcible apposition causes much less pain than superficial pressure, and electrical reaction remains normal. The knee joint is the one most often affected, and next to this the hip and wrist. The smaller articulations are rarely involved. Hyperesthesia of the scalp is usually associated with an intense headache. A reflex headache is a common symptom of utero- ovarian disease. It is aggravated by emotional disturbance, and is particularly liable to recur at each menstrual period. The pain is oftener located in the vertex or the occiput, but not infrequently it partakes of the character of neuralgia, implicating the occipital, and different branches of the fifth nerve; or there may be hemicrania, or clavus hystericus. Following these attacks of headache hyperesthesia of the scalp, or of the underlying muscles, is often marked. The genito-urinary system frequently becomes hyperesthetic. The external genitals, the bladder and urethra, are oftener sensitive because of actual disease; they may, however, become ex- quisitely so without any demonstrable cause. That condition known as hysteralgia is likewise a purely functional disorder without any textural change in the uterus to account for the pain. Coccygodynia with hyperesthesia is sometimes purely reflex, but usually it is the result of structural disease in or about the bone. THE HYSTERO-NEUROSES: HYSTERIA. 195 Pain and hyperesthesia of the back may result from over sensi- tiveness of the vertebral periosteum, from increased muscular sensibility, or it may be entirely superficial. The most fre- quent seat of superficial pain along the back is between the scapulæ, but it often makes its appearance alternately along different portions of the spinal column; or it may present simultaneously at different and widely separated points. Fre- quently the area supplied by the intercostal nerves passing from the vertebral column at the sensitive point is painful, giving rise to so-called intercostal neuralgia. When hyperesthesia affects the region of the vertebral column in this way it is known as spinal irritation. There is no doubt that it exists as one of the forms of the hystero-neuroses and, if so, will disappear on curing the pelvic lesion. The exact pathological condition of the structures involved is yet an unsettled point. Valleix* considers the condition one of the manifestations of hysteria. Inman† ascribes the pain excited by pressure over the spinous processes to an involve- ment of the muscular attachments. Erichsen, Hammond, § and Gowers || believe that the pain radiating from the spine, when structural lesions are absent, is due to anemia of the posterior columns of the cord. The explanation last given is probably the correct one, as it is in harmony with the fact that spinal irritation oftener occurs in anemic subjects. It is very important to differentiate between simple spinal irri- tation and chronic myelitis, meningitis, and congestion. In myelitis there is often anesthesia instead of hyperesthesia ; the muscular contractions are frequent and painful, and there is a sensation as if a tight cord were tied around the body at the upper limit of the paralysis. (Hammond.) The bladder and rectum are frequently implicated, and paralysis with atrophy is sooner or later developed. When paralysis results from * "Traité des neuralgies, ou affections douloureuses des nerfs," p. 345. †“On Myalgia: its Nature, Causes, and Treatment,” p. 225. "On Concussion of the Spine, etc.,” p. 188 et seq. "Diseases of the Nervous System," 1886, p. 399 et seq. || "Diseases of the Nervous System," 1888. 196 A TEXT-BOOK OF GYNECOLOGY. spinal irritation, which is seldom the case, it is rarely complete, and there is never atrophy of the muscles involved. Myelitis, unless arrested, steadily progresses toward a worse condition, which is not the case with spinal irritation. In spinal meningitis there is persistent pain in the cord, and the spinal tenderness is not increased by pressure. Painful spasms of the muscles of the back is a constant symptom. sa In congestion of the cord there is no spinal tenderness, and all of the symptoms are aggravated by the recumbent posture, because in this posture the blood gravitates toward the spinal centers. Pain over a circumscribed area of the extremities may resemble very closely a periostitis. Illustrative Cases. CASE I.—Neurosis of the Anterior Tibial Region Simulating Periostitis. Cured by Emmet's Operation.—Mrs. T. L., æt. 28, presented herself at the surgical clinic of Professor H. L. Obetz during the fall of 1887. Her chief distress, and the only symptom of which she complained, was a circumscribed tenderness over the anterior tibial region of the left side. It dated from the birth of her first and only child two years previously. The pain was constant and persistent, worse during menstruation and after getting warm in bed. It was unaffected by the weather. She had been subjected to local blistering and constitutional treatment without avail. There was nothing of the "hysterical" about her temperament, being exceedingly phlegmatic and with no trace of psychical disturbance. There were no evidences of heat or swelling, and the case was referred to me for local examination. I found a badly lacerated cervix and perineum, which were repaired in the usual way. In two weeks after the operation the pain in the limb had entirely disappeared, and remained absent until eighteen months subsequently, when she gave birth to a second child. It then returned, and an examination revealed a recurrence of the laceration. Up to the present time she has not submitted to a second operation, and the pain persists. CASE II-Hysterical Joint of Three Years Duration, Simulating Morbus Coxarius, Cured by Directing the Treatment to the Pelvis.-Miss E., a bright, intel- ligent girl, æt. 19, consulted me during the spring of 1890 for what had been diag- nosed as hip-disease. Three years previously she fell down stairs while at school, striking upon the buttocks, soon after which she was taken with a severe pain in the occipital region, which compelled her to leave school. In a short time the left hip began to pain her, when she took to her bed and never walked up to the time of con- sulting me, except for a short period while wearing a brace. She had consulted various physicians of various schools, had submitted to all kinds of treatment, in and out of sanitariums, without avail. She was brought to me in an invalid's chair. The first point that impressed me was that the girl did not look ill. I learned that she commenced to menstruate at thirteen, puberty precipitating an attack of chorea. The THE HYSTERO-NEUROSES: HYSTERIA. 197 flow never became regular, and was always scanty and very painful. A yellowish leucorrhea had persisted since her injury. The hip joint was excessively tender upon pressure, but there was no local increase of temperature, no evidences of fever or suppuration, and forcible apposition, by striking the heel, was not very painful. More or less spastic contraction of the flexor muscles of the affected side existed, which gave to the limb an appearance of shortening, which was very deceptive. The mother informed me that hysterical symptoms were common. Irritability of the bladder, with alternate diarrhea and constipation, frequently occurred. On examination I found the left ovary very tender, with more or less inflammation of the whole genital tract. The local examination increased the pain in the hip most decidedly, and caused much nervous agitation. I did not, therefore, deem it wise to recommend local treatment other than the hot douche with calendula, which was faithfully carried out. I put around the ankle of the affected leg three pounds of bar-lead, prescribed a pair of crutches, and insisted upon her walking. The lead was used to overcome the spastic contraction, as well as for its moral effect. I did not deem the joint lesion of such a character as to need extension. Ignatia was the only remedy given internally. I heard nothing more from the case until after my return from a six-months' absence abroad. She then wrote: "I wore the weight until my left limb was nearly as long as my right, and can now walk perfectly well with the aid of a cane, though it hurts me some. I have taken no medicine except the prescription you gave, and have not deemed it necessary, because of the great improvement." She has now, three years later, recovered perfectly, having discarded the cane soon after writing the foregoing letter. CASE III.—Distressing Hyperesthesia of Sight and Hearing.—Mrs. æt. 47, a widow for twenty years. She is a devoted church woman and for many years was a leader in all charitable work done in the community in which she resided. Through friends she was urged to consult me, and I think that the call to the neigh- boring town in which she lived was countermanded at least four or five times before she finally mustered up sufficient courage and strength to see me. Upon reaching her bed-side I found my patient in a room made dark by closed blinds, over which were hung heavy blankets to shut out every ray of light. The mirror was turned to- ward the wall for fear a ray of light might strike it and flash throughout the darkened room. Nor did the patient rest under these extreme precautions, for the eyes were protected with two pairs of colored glasses with side attachments. Hyperesthesia of the sense of hearing was equally marked, and noise was excluded from the room by double doors whose keyholes were stuffed with cotton. She also had her ears filled with cotton, over which she wore ear-mufflers. She was emaciated to an ex- treme degree, and had been reduced to her miserable condition by a series of events which so frequently precede profound neurasthenia. Her husband was killed during the war and she was left childless. Twelve months previously to taking to her bed she nursed her mother through a long and fatal illness. This greatly prostrated her, yet she kept up until a favorite brother-in-law was thrown from a carriage and killed. This was the last straw, and the shock compelled her to take to her bed. In due time loss of appetite with irritability of the stomach developed, which of course led to marked depravity of nutrition. With the anemia came the hyperesthesia of the special senses, spinal irritation, headache, hysterical manifestations, etc. There was no serious pelvic lesion, although she had been much treated for an alleged uterine 198 A TEXT-BOOK OF GYNECOLOGY. displacement with congestion. Unfortunately, she was encouraged instead of discour- aged in her invalidism and she soon became a nosomaniac of the worst type. With great difficulty the patient was moved on a couch to a private hospital and placed under the Weir Mitchell treatment. I ignored the pelvic trouble entirely. It is unnecessary to give in detail the progress of the case from day to day after this treatment was inaugurated. Suffice it to say that the improvement was of the most marked character, and in six weeks from the time she entered the hospital she walked to her carriage with her eyes and ears unprotected. She soon resumed her church and charitable work, in which she again finds much enjoyment. (6) Anesthesia.-Anesthesia may temporarily impair any or all of the senses. The sense of touch is, however, oftenest affected. Henrot, Szokalsky, and Gendrin affirm that general or partial loss of sensibility follows every hysterical attack. So good an authority as Jolly, however, considers this statement too sweep- ing. Alternate surfaces of the body are frequently affected, and hyperesthesia may supplant the anesthesia of the part first attacked. All sensations are sometimes absent, but usually that of pain alone is abolished, while those of heat and pressure remain normal. The entire surface of the body is rarely im- plicated. Hemianesthesia occurs oftener on the left side. (Char- cot.) The most frequent seat, when circumscribed, is the dorsal surface of the hands and feet and the regions of the outer ankles. Cases of self mutilation occur in women while in an analgesic state. Many interesting and almost incredible instances of such mutilation have been recorded by Cullingworth, Channing, t Andrews, Jolly, § and others. || * Loss of sensibility of the muscles, bones, and joints may be * Op. cit., p. 855. † American Journal of Insanity, January, 1878. ‡ Journal of Mental Science, July, 1875. ? Ziemssen, Vol. xv, p. 507. || In one of Dr. Channing's cases the following is a list of articles which were re- moved from the patient's arm and saved: "Ninety-four pieces of glass, thirty-four splinters, two tacks, four shoe nails, one pin, and one needle. Several pieces of glass and the pins and needles first removed were, unfortunately, mislaid and lost. Including these the whole number of objects removed amounted to one hundred and fifty. * * * The longest splinter was nearly six inches long." Dr. Channing thinks that she experienced acute erotic pleasure from the probings to which she was subjected. THE HYSTERO-NEUROSES: HYSTERIA. 199 associated with the cutaneous anesthesia. Muscular contraction is only temporarily impaired, if at all; in some instances there may be difficulty in executing passive movements of the limbs with the eyes closed. Anesthesia of the mucous membranes is a frequent symptom in the hysterical. It may or may not be associated with the loss of cutaneous sensibility of the neighboring parts. The mucous membranes of the respiratory, genito-urinary, and alimentary tracts are the ones most frequently affected, and, as a result, there is diminution or loss of reflex excitability of the parts involved. When the rectum and bladder are the organs implicated the presence of feces or urine fails to create a desire for evacuation, and the distention often becomes very great without exciting pain. Scanzoni, in four of his patients, found complete anesthesia of the vaginal mucous membrane with an absence of all sexual desire. Deafness and visual disturbances likewise result from anes- thesia, occurring particularly in conjunction with hemianesthesia, and are therefore usually unilateral. (Charcot.) The visual dis- turbances not infrequently terminate in amblyopia and amaurosis. An ophthalmic examination rarely discloses any textural change of the eye. ALTERATIONS OF MOTILITY. (a) Clonic and Tonic Spasms.-In dealing with the various forms of clonic and tonic spasms the same difficulty may present in distinguishing those that are reflex from those depending upon direct motor excitation that often presents in distinguishing a reflex pain from pain due to actual disease. It is often neces- sary to remove possible causes within the pelvis before an accurate diagnosis can be made. Clonic or tonic spasms of hysterical origin may implicate any muscle or muscles of the body. When the pharynx is involved it gives rise to that peculiar sensation known as globus hystericus. (Hammond.) Other writers attribute the peculiar sensation so often felt in the throat to a reversed peristalsis of the esophagus. (Jolly.) Eulenberg considers it a sensory and not a motor phenomenon. It is certain that the esophagus is frequently the seat of hysterical spasm which, under certain circumstances, 200 A TEXT-BOOK OF GYNECOLOGY. continues long enough to simulate organic stricture. A similar spasm not infrequently implicates the stomach, intestines, and bladder. A tonic spasm of the limbs causes contractions, a symptom, which, especially when accompanied with paralysis, suggests very forcibly the possibility of organic lesion. These contractions may last for an indefinite length of time. Charcot cites a case of eighteen years standing. The patient was first seized with an hysterical paroxysm which was followed by paraplegia and contraction. Hammond says he has frequently seen such con- tractions last for several months. mon. (b) Paralyses.-So-called hysterical paralysis is not uncom- It is either restricted to individual muscles, or occurs, as it oftener does, in the form of hemiplegia. Hysterical aphonia, coming and going suddenly, is due to paralysis of one or more of the laryngeal muscles. However, aphonia due to reflex causes, may and often does persist until the cause is removed. Reflex paraplegia may be partial or complete. If the lower extremities are involved, and the paralysis is incomplete, the patient has a peculiar gait, unlike that of any organic disease of the cord. By the aid of crutches or articles of furniture within her reach she drags her limbs along. As in all hysterical affec- tions, her ability to walk is very variable, depending much on external circumstances, as well as the state of her own mind. CASE IV.-Reflex Paraplegia, Due to Anteversion and Urethral Fissure.-Mrs. W., æt. 33, Muskegon, Michigan, presented herself at my clinic October 7, 1886, with symptoms of locomotor-ataxia. Married for twelve years. Never pregnant. Illness dates back for six years. First noticed inability to mount staircase owing to weakness and tremor of limbs. Could not walk unless looking at feet, and couldn't stand with eyes closed. There was a burning pain over the sacrum. Urination pain- ful and frequent, the bladder being emptied many times during the twenty-four hours. The urine was perfectly normal. Feet and hands cold. The uterus was anteverted, and the urethroscope showed a fissure at the neck of the bladder. The dysuria was entirely overcome by forcible dilatation of the urethra, after which an anteversion pessary was fitted, argentum nit., 6x, given internally, and the Faradic current applied once per day. She returned home December 3d much improved, though not well. I have not been able to hear from her since. I should have added that elec- tricity had been faithfully used before coming to me. The rôle played by the argen- tum nitricum should not be underestimated, for the indications were clear cut, and it covered the case beautifully. THE HYSTERO-NEUROSES: HYSTERIA. 201 CIRCULATORY DISTURBANCES. General Considerations.-In another place* I have endeav- ored to show the important and intimate connection existing between the generative organs and the vaso-motor system of nerves. Inasmuch as the vaso-motor system presides over the circulation, it is certainly not remarkable that the circulatory equilibrium should be upset by utero-ovarian disease. Dilata- tion and contraction of the vessels and capillaries result in response to a peripheral stimulus, so that no system is more quickly implicated as a result of reflex impressions than the circulatory. The cold pallor of contracted, and the hot flush of dilated, capillaries are symptoms frequently witnessed when the utero-ovarian functions are disturbed, as during the change of Such disturbances may be either (a) central or cardiac; or (¿) peripheral or vascular. life. (a) Central or Cardiac.-In the August, 1886, number of the American Journal of Obstetrics will be found a most excellent article by H. J. Bolt, M. D., entitled "Cardiac Neuroses in Con- nection with Ovarian and Uterine Disease." Doctor Bolt states in this article that cardiac neuroses are present in eight per cent. of all cases of uterine disease, and classifies them as follows: 1. Palpitation; 2. A disturbance of the rhythm (irregularity); 3. A distinct suspension of a distinct beat (intermittence); 4. Angina pectoris. Palpitation of the Heart is a common symptom resulting from pelvic lesions, and, frequently, the only one of which the patient complains; at least it so absorbs her attention and excites her apprehension as to make her oblivious to all other incon- veniences. It is always made worse by nervous excitement, as the heart's action in no small degree is governed by the emotions and the state of the mind. Pain frequently accompanies the palpitation, sometimes extending to the left shoulder and down the left arm. It may be sufficiently severe to amount to an angina pectoris. * Chapter VIII. 202 A TEXT-BOOK OF GYNECOLOGY. The palpitation is generally paroxysmal in character, though it may be continuous. It often occurs immediately upon lying down at night, preventing the patient from getting to sleep; or it is worse during digestion. The sensation of palpitation is frequently much greater than it really is, so that the patient complains of the violence of the heart's action when indeed it is normal, or but little disturbed. This can be accounted for only by the increased sensitiveness of the heart and the surrounding structures, thus making the patient painfully conscious of the ordinary movements of the organ. (Byford.) Intermittency and irregularity of the heart's action, though not a frequent neurosis, does sometimes result from a "modification of the rhythmic discharge in the cardiac ganglia." (Bolt.) It stands to reason that a reflex palpitation existing for an indefinite length of time is capable of producing an organic lesion of the heart, which would thus no longer be a pure neurosis. I believe, however, that disturbance of rhythm is often, and that intermittency is occasionally, the result of uterine disease. Loomis* affirms that angina pectoris is always the result of organic heart disease. Fothergill, Peabody, and Fluck,† on the other hand, maintain that angina pectoris without organic disease is a possibility. Admitting that, in at least the larger number of instances, the symptom is the result of an evident organic lesion, the fact remains that in a limited number of cases of suspected organic disease, with severe anginal symptoms, an autopsy reveals no demonstrable disease. (6) Peripheral or Vascular.-The phenomena referable to reflex disturbance of the peripheral circulatory system result from the irregularity of distribution of the blood. Flushes of heat, undue redness of the face, cold hands and feet, a sensation of heat located on the top of the head, or in the occipital region, or extending into the spine, burning in the sacrum and loins, etc., are symptoms due to vaso-motor disturbance. If the vaso-motor paralysis is limited small blotches of erythema, perhaps not * "Practical Medicine,” p. 504. +"Pepper's System of Medicine,” Vol. 1, p. 750. THE HYSTERO-NEUROSES: HYSTERIA. 203 larger than a fifty-cent piece, may appear upon any portion of the body—the back, chest, face, or limbs. Ecchymoses smaller than the erythematous spots are occasionally seen. These symptoms occur not infrequently in conjunction with morbid perspirations. (Tilt.) The symptoms enumerated occur more frequently during the menopause than at any other time, and cannot always be justly relegated to the category of hystero-neuroses. They are un- doubtedly many times due to increased intra-arterial pressure, the result of the cessation of menstruation. In proof of this the same symptoms sometimes follow oophorectomy in young and middle aged women. An hyperesthesia of the mucous membrane in the region of the internal os is, however, usually present when these symptoms persist, and they will often vanish as by magic after dilatation and curetting. Lesions of the rectum may likewise perpetuate vascular disturbances. The several forms of vicarious hemorrhages are dealt with in another chapter. Illustrative Cases. CASE V.-Cardiac Neurosis resulting in Organic Disease associated with and prob- ably caused by laceration of the cervix. Greatly relieved by Emmet's operation.— Mrs. W. was brought to my clinic on November 30th, 1886, by her physician, Dr. Wheelock of Bancroft, Michigan. She was 51 years of age, possessed a good family history except that one sister suffered from periodical attacks of insanity. Has had four children. She did not get up well from the birth of her last child, soon after which she began to have severe attacks of palpitation, which were always worse during menstruation. An examination of the heart revealed undoubted dilata- tion and great irregularity. The uterus was prolapsed, enormously swollen and con- gested, the lips everted and so greatly hypertrophied as to almost present externally. The hypertrophy was so great as to make partial amputation necessary. Much cica- tricial tissue was removed. The patient nearly died during the operation from the effects of ether; however, she made a splendid recovery, and for two years her health was infinitely better. The heart symptoms improved simultaneously with the local improvement, but because of the organic changes never entirely disappeared. She died two years subsequent to the operation, after some undue exertion, from heart failure. CASE VI.-Cardiac Neurosis simulating Exophthalmic Goiter caused by retroversion and endometritis.-L. M., æt. 40, unmarried. Had for years suffered from local pelvic distress, leucorrhea, bearing-down pain, backache, occipital headache, etc. She came to me during the month of April, 1886, because of a severe palpitation of the heart which had persisted for six months or longer. The pulse ranged from 120-160 beats per minute. The eyes were very prominent, one being more so than 204 A TEXT-BOOK OF GYNECOLOGY. the other. There was suspicious enlargement of the thyroid. An examination re- vealed a retroversion with more or less chronic endometritis, both cervical and cor- poreal. I reposited the uterus, fitted a Hodge pessary and cured, by appropriate treat- ment, the inflammatory condition. Gelsemium, cimicifuga and kali carbonicum were given internally. In six months' time the heart's action became perfectly normal and the thyroid returned to its natural size. The eye symptoms still persist in spite of the best directed efforts of some of the most prominent oculists in America. CASE VII.-Cardiac Pain simulating Angina Pectoris due to pelvic lesions.—Mrs. M., æt. 29. Married eleven years; never pregnant; menstruation began at 12 years. The present trouble dates from the time of matrimony. Was said to have inflamma- tion of the womb four years ago. Complains principally of pain in the heart, which is described as paroxysms of " piercing and sticking,” and in the intervals as a dull con- tinuous pain, which traverses down the left arm. Two tender points are present on pressure over the precordia. Dysmenorrhea and other symptoms are present which point to uterine trouble. Diagnosis.—Retroversion of the portio vaginalis, with the body of the uterus pushed slightly to the left. An old exudation is felt on the right side. Chronic endometritis. Patient cured on directing treatment to pelvis.-Dr. H. J. Bolt, in the American Journal of Obstetrics. CASE VIII.-Circumscribed Erythema of the Lower Limbs in a young hysterical girl of 18. Retroversion. Cured.—The patient, of German parentage and not particu- larly intelligent, was, I am convinced, an onanist. The most striking symptom was the appearance, about four days previous to each menstruation, of two erythematous patches on the anterior thigh of each side, midway between the knee and body. These patches were perfectly symmetrical and about the size of a silver dollar. The patient was entirely cured by correcting the uterine displacement. CASE IX.-Menorrhagia with marked Vaso-motor Disturbances cured by dilating the cervix and curetting.—Mrs. A., æt. 51. Married. Profuse menorrhagia, recur- ring about every six weeks. During the intervals vaso-motor disturbances of all kinds-cold hands and feet, flushes of heat, alternate redness and paleness of the face, oppression of breathing, etc. The uterus was greatly subinvoluted and the mucous membrane at the internal os most exquisitely sensitive. Entirely cured of all hemorrhage and nervous symptoms by forcible dilatation, curetting, and the application of iodin. Lachesis had modified the nervous phenomena previously to the operation, but only gave temporary relief. ANOMALIES OF SECRETION AND EXCRETION. Urine. The secretion of a large quantity of limpid and almost odorless urine frequently results from nervous excite- The physical character depends upon the excess of water and the deficiency of salts. Again, in uterine patients, the salts may be increased in quantity and the water diminished. When the urine is decidedly morbid in its composition, how- THE HYSTERO-NEUROSES: HYSTERIA. 205 ever, it is usually secondary to gastric and hepatic derangements. Abnormality of the urine, especially if it be excessively acid or alkaline, frequently excites painful micturition. It may be greatly diminished or almost absent instead of increased in quantity. Salivation. Both salivation and abnormal dryness of the mouth have been observed in hysterical and uterine patients. Dr. H. W. Longyear of Detroit, has reported a case of "per. sistent salivation, apparently due to laceration of the cervix uteri." The profuse flow of saliva, which had persisted for more than a year, was only cured by closing a rent in the cervix. Dr. Babcock of Jamestown, N. Y., consulted me in regard to a similar case.† After an hysterical paroxysm, the salivation may be apparent only, escaping from the mouth because, owing to spasm or paralysis of the pharynx, it cannot be swallowed. (Valen- tiner.) Salivation is frequently associated with pregnancy, and may be the first warning which the patient has of her condition. Abnormal and anomalous secretions may proceed from the uterus, the vagina, the breasts, the liver, the stomach, and the bowels. As a result of utero-ovarian disease a vicarious leucor- rhea is not uncommon and is dealt with in the succeeding chapter. Those arising from the other organs will in due time be considered seriatim. Disorders oF RESPIRATION. The painful spasm in the region of the throat has already been referred to under the designation of globus hystericus. This feeling of constriction often gives rise to obstructed respi- ration, inducing a fear of fatal suffocation. Again there may be a sensation as if smoke or dust were being inhaled. Engel- mann cites many interesting reflexes of the respiratory organs resulting from pelvic lesions-pharyngitis, tonsilitis, bronchitis, asthma, etc. Byford says he has seen "imperfect respiration or * American Journal of Obstetrics, January, 1883. † I have within the last week operated upon a woman, aged forty-two, for laceration of the cervix and complete laceration of the perineum, who has for two years been greatly annoyed by a profuse salivation. The case is yet too recent to note the effect of the operation. 206 A TEXT-BOOK OF GYNECOLOGY. "" partial inflation of one lung, or parts of the lungs in the hystero-neurotic. When this condition is associated with a cough, which in some women is exceedingly persistent, it gives rise to much concern. A reflex asthma is sometimes most distressing and obstinate, and does not always disappear after the local cause is removed. Illustrative Cases. CASE X.-Hysterical Cough, with Anteflexion and Dysmenorrhea.-Patient æt. 18, German. Hysterical paroxysms have been frequent. At each menstrual period she suffered from a persistent dry, hacking cough, which was kept up while awake during the entire menstrual period. I deemed a local examination advisable, but upon attempting one the cough was greatly aggravated. However, I succeeded in diagnosing an anteflexion. Because of the nervous and erotic symptoms excited by the examination I did not deem it wise to resort to local treatment. The cough continued to recur for twelve months, when it gradually disappeared. CASE XI.—Reflex Asthma Temporarily Cured by the Removal of the Appendages of One Side. Recurrence and the Removal of the Appendages of the Other Side. Recurrence of Asthmatic Attacks after a Respite of Three Months.—Miss C., æt. 40, Owasso, Michigan. I was requested to see this patient by her physician, Doctor B. F. Knapp, while making a professional visit to Owasso for another purpose. The patient had been in poor health for three years, suffering from an ovarian displacement, and as all efforts at reposition were without avail, she presented herself at our college clinic on October 19, 1887. Three years previously to this date, while picking peaches, she felt something "give way" in the region of the pelvis, causing some pain, which was relieved by steady pressure over the pubes; following this accident she suffered after each stool the most excruciating pain, which was bearing-down in character and frequently excited nausea. This pain lasted for an hour or longer, extending into the spine, and, owing to its severity, defecation was delayed until constipation had become chronic, cathartics and enemata being always necessary to move the bowels. Dysmenorrhea was a prominent symptom, the pain preceding the menstrual flow for two or three days. A reflex asthma during the period was a frequent complication, during which the respiration was greatly embarrassed, the skin bathed with cold, clammy perspiration, the pulse weak and thread-like, and the features drawn and con- tracted. A digital examination revealed a tumor in the posterior cul-de-sac, which counter-tests proved to be the left ovary. The bimanual showed the right ovary to be in its normal position and seemingly healthy. The prolapsed ovary, however, was enlarged to twice or thrice its normal size, and was exquisitely tender. All efforts made to return the displaced organ to its normal position were futile. The patient was ordered a hot vaginal douche twice a day, with a tampon made from flaxseed tied in a small muslin bag, dipped in hot water, and gently placed in the posterior vaginal fornix. Nux vomica 3x was prescribed four times a day. November 3, 1887. Being satisfied that nothing short of a radical operation would afford permanent relief, I removed the offending organ through the abdomen. The ovary was adhered to the floor of the posterior cul-de-sac, though the adhesions were THE HYSTERO-NEUROSES: HYSTERIA. 207 separated with little difficulty. The abdominal walls were unusually thick, and some difficulty was experienced in withdrawing the ovary far enough to include both the ovary and the tube in a Staffordshire knot. The right ovary and tube seemed per- fectly normal, and were, very unwisely, left behind. The abdominal wound was closed in the ordinary way, and the patient placed in bed. Briefly, her history from the above date to January 11th was as follows: Convalescence progressed favorably for two weeks, the temperature not exceeding 100° and this elevation could be accounted for by more or less irritation of the abdominal wound. The patient for a time even felt much relieved. At her next menstrual period, however, she suffered an unusual degree of pain, the temperature reaching 102°. All of the old symptoms of strangury and pain after defecation returned with increased severity. The asth- matic attacks recurred very much oftener than ever before, and prostration was cor- respondingly great. A vaginal examination revealed the right ovary in the same locality formerly occupied by the left. It, too, was enlarged and tender. In short, the intra-peritoneal irritation incident to the removal of the left ovary had set up an inflammation of the appendage left behind, resulting in its prolapse and adhesion. She very gladly submitted to the second operation, which was done on January 11th, just two months and nine days after the first. An incision was made a little to the right of the old cicatrix, the ovary separated from the floor of the cul-de-sac, tied as in the former case, and removed with the tube. The first ovary had undergone cystic degeneration, and the tube was distended with water; the last presented all of the evidences of subacute inflammation, a small circumscribed abscess containing perhaps a teaspoonful of pus occupying a portion of its stroma. Convalescence was almost, if not quite, uninterrupted after the second operation; the abdominal wall, owing to its excessive thickness, causing the only impediment. The bowels were moved on the third day with little or no pain, and soon became perfectly regular. Under the date of March 1st she writes: "I am feeling better than I have for years. My bowels are perfectly regular, and I have no more of those nervous spells. I enjoy visiting with my friends very much, and cannot thank you sufficiently for what you have done for me."'* CASE XII.—Reflex Asthma of Eighteen Years Standing. Cured by Removing Prolapsed Tissue from the Urethra.—Mrs. S., æt. 47, sent to me by Dr. S. L. Porter of Vernon, Mich. Married for 26 years, and has given birth to three children, the eldest being 25 and the youngest ten years of age. Her present trouble dates from the birth of her second child, 18 years ago. Dysuria has persisted ever since. The patient was haggard and emaciated from her extreme suffering. A severe asthma, recurring at variable intervals, persisted during the entire 18 years. Upon local examination I found an exquisitely sensitive and tender tumor as large as a pullet's egg, completely surrounding the external meatus of the urethra. This was * In a letter dated December 31, 1890, the patient reports herself as bad as ever, so far as the asthmatic attacks are concerned. If the asthma was a genital- reflex, its persistence can be explained only upon the theory that the nerve terminals are still involved in the cicatrix. I record the case under this head to show how extremely difficult it is to determine the reflex origin of any symptom without first removing the local lesion. 208 A TEXT-BOOK OF GYNECOLOGY. + ligated and removed. I never witnessed more rapid and greater improvement than ensued. She began to gain at once, and she never suffered from an asthmatic attack after the operation. She gained in flesh 25 pounds in three months. I heard from her in December of 1890, five years after the operation, at which time there had been no recurrence of the old symptoms. CASE XIII.-Reflex Aphonia · Resulting from Pelvic Inflammation with Involve- ment of the Appendages. Cured by Salpingo-oöphorectomy.—Patient sent to me by Dr. W. H. Frost of Tecumseh, Mich.; æt. 42; unmarried. She came to my clinic February 18, 1888. She was bed-ridden, could not stand on her feet, and had had absolute aphonia for 12 years, dating from an attack of typhoid fever, with probable pelvic complication. At any rate, her pelvis was a mass of inflammatory exudates; there was menorrhagia, which added each month to the anemia, already profound. Menstruation was very painful. Salpingo-oöphorectomy was performed and recovery from the operation progressed without any untoward symptoms. The patient surprised us all by talking the day following the operation. Her general health began to improve, she got on her feet, and in six weeks returned home nearly well. This favorable condition continued for six months, when, owing to imprudence because of her favorable progress, she was taken with peritonitis and died. Her imprudence consisted in walking several miles during inclement weather to a family reunion. CHAPTER XV. THE HYSTERO-NEUROSES: HYSTERIA. (Continued.) DISORDERS OF THE GASTRO-INTESTINAL CANAL. Gastric Neuroses.-The vagus is a bridge which unites the central portions of both nervous systems. (Tilt.) It is not well isolated and resembles both. By anastomosing with the sym- pathetic it helps to form the celiac plexus, so that when it be- comes deranged the epigastric ganglia sympathize. As a result the viscera, through their ganglia, react upon the brain, caus- ing paralysis of the epigastric centers. In this way the appetite becomes perverted, and often there is in the gastric region a feeling of sinking and faintness; or there may be gaseous dis- tention of the stomach with belching and nausea and vomiting. Indeed, indigestion and symptoms of gastritis frequently result from either morbid or physiological changes in the reproductive organs. The nausea and vomiting of pregnancy occur in response to a physiological change of these organs-or rather they often present themselves when local morbid conditions are not demonstrable. In due time the nutrition becomes seriously affected because of the indigestion. So-called hysterical vomiting may be a most distressing and persistent symptom. At times it is apparently due to an increase of the gastric secretion, as fasting patients will eject enormous quantities of fluid. Again it may be a vicarious act on the part of the stomach, as both Charcot and Fernet have found urea in the vomited matter. A gastric neurosis is differentiated from organic disease of the stomach by observing the following points:- 1. The symptoms subside upon curing the local lesion. 2. Articles of diet which would aggravate organic lesions are frequently the only ones retained in a neurosis. 14 209 210 A TEXT-BOOK OF GYNECOLOGY. 3. Exacerbation of the gastric symptoms occurs simultaneously with an exacerbation of the pelvic symptoms. implicate the 4. Entire absence of the evidences of organic disease. Intestinal Neuroses.-The intestinal secretions may be defi- cient or excessive in uterine disease, giving rise either to consti- pation or diarrhea. The constipation is sometimes exceedingly obstinate, there being no tendency for the bowels to move with- out artificial aid. The diarrhea and constipation frequently alternate. When due to deficient secretion, the stools are dry and hard; when due to deficient peristaltic action, they are per- fectly normal as regards consistence, color, etc. Both hyperesthesia and anesthesia frequently mucous membrane of the gastro-intestinal canal. With the first, everything that comes in contact with the mucous membrane excites contraction and induces pain. Food may be ejected before passing into the intestine; if it is not, its presence in the intestine excites exaggerated peristalsis, and the food is hurried on through the canal before it is digested. Frequent evacua- tions of the bowel are thus induced. Should the hypersensi- tiveness be limited to the rectum, great distress is caused by the presence of the slightest amount of fecal matter. In a chapter entitled "The Rectum and Defecation in Hysteria,"* Weir Mitchell records a case so bad that the patient was compelled to wear a napkin over the anus, notwithstanding that the stools were normal in consistence. In anesthesia there is deficient instead of exaggerated peristal- sis. It may amount to almost a paralysis of the intestinal canal, although the anesthesia is usually limited to the lower intestine. Enormous accumulations of perfectly-formed fecal matter may lodge in the whole lower half of the descending colon, or merely in the sigmoid flexure. So obstinate is the retention that a stricture is sometimes suspected. Diarrhea, with profuse, watery and exhausting discharges, occasionally accompanies uterine disease. The kind of ingesta seems to have but little influence upon the discharge, and an attack is particularly liable to occur during menstruation. * "Nervous Diseases," p. 252. THE HYSTERO-NEUROSES: HYSTERIA. 2II Gaseous distention of the intestines is likewise a frequent symptom of uterine disease. It is often tumultuous, and the distention may be so great as to give rise to symptoms of pregnancy. During the hysterical paroxysm it not infrequently becomes a prominent and most distressing feature of the attack. Byford calls attention to the expulsion of muco-fibrinous casts from the intestinal canal as a result of uterine disease-a symp- tom which I have observed in a number of cases. It is a sort of membranous enteritis, and the quantity of casts discharged at one time may be very great. They consist either of shreds of mucous membrane or complete casts of the intestinal tube. I am not aware that any other author mentions these casts in connection with uterine disease. The cases observed by me recovered fully after the pelvic trouble disappeared. The gastro-intestinal reflexes are likewise frequently excited by rectal lesions. The gynecologist who ignores this fact will often fail ignominiously in his attempts to relieve his patients. Illustrative Cases. CASE XIV.-Acute Vomiting for Two Years, due to Anteflexion of the Uterus.— Patient æt. 25. Had suffered during the entire two years from almost incessant vomiting and occasional hematemesis. The uterus was found soft and anteflexed (with posterior rotation). Suitable treatment in a short time completely removed the vomiting.-Hewitt. CASE XV.—Membranous Enteritis during Climaxis.—Patient æt. 48; married; has had four children. Was bed-ridden for nearly two years with general nervous prostration. I was called to see this patient after she had been in bed for nearly a year. Menstruation had ceased, but the psychoses were very prominent and insanity was greatly feared. For nearly ten months after I saw her she passed enormous quantities of membranous masses, which were sometimes discharged in the form of a ball resembling parasites. There was chronic metritis. After the symptoms incident to the menopause disappeared she made a complete recovery. • CASE XVI.—Reflex Intestinal Neurosis.-Miss H., æt. 15, under treatment for vesical weakness, is suffering from nervous prostration. The patient had been affected with habitual constipation, which yielded but slowly to treatment. For a few days before the appearance of the first flow, I believed that a natural action of the bowels had been accomplished and a healthy tone restored; the constipation seemed overcome. After the cessation of the flow the previously existing conditions were reëstablished. With the advent of the second menstrual period the patient was seized with a diarrhea, uncontrollable at times, so that I found her in tears from mortification at her distressing state. One passage followed another. This annoying 212 A TEXT-BOOK OF GYNECOLOGY. reflex persisted during the two days previous to the flow, yielding to constipation during its continuance, and returning again for 36 hours after cessation of the The third period was accompanied by the same symptoms, together with numerous other reflexes.-Engelmann. menses. Disorders of THE SKIN (Dermatoses). In studying nervous lesions and nervous phenomena it is par- ticularly difficult to distinguish between coincidences and actual effects. This is especially true in dealing with the so-called dermatoses. Some of the tests applied to other forms of hystero- neuroses must be applied with a certain degree of reservation in skin diseases. It has been shown that nearly if not quite all of the hystero-neuroses are aggravated by menstruation, and the der- matoses form no exception to this rule; but most skin diseases, of whatever origin, are made worse by any cause which intensi- fies the hyperemia of the skin, and menstruation will do this. It is, therefore, no sign of its uterine origin that a skin affection is made worse by menstruation. However, testimony is not wanting which conclusively proves that the utero-ovarian func- tion exerts no small influence upon the skin, both for good and for evil. The acne of puberty and the pigmentation of preg- nancy are recognized by all as dependent upon physiological changes within the pelvis. The symmetry of these changes points unmistakably to their nervous origin. Thus Godson cites a case, which is quoted by Engelmann, of a girl sent to St. Bartholomew's Hospital for chorea in her seventh month of pregnancy; the areola of both breasts were perfectly formed, except about one-third of their circumference, which was per- fectly free from discoloration. The area was sharply limited and almost exactly symmetrical on the two sides. Barnes, in commenting upon this case, remarks that it is inconceivable how any difference in the quality of the blood going to the parts could exist. Engelmann observes that it is upon the larger surfaces of the body where the most peculiar and symmetrical configurations are traced, precisely the same on both sides, but that they often escape observation because concealed by the clothing or bedding. While, then, it is true that pigmentation and other forms of skin disease may often depend upon changes THE HYSTERO-NEUROSES: HYSTERIA. 213 within the circulatory system, there is indisputable evidence bearing upon the utero-ovarian origin of many cases which have been cured only by directing the treatment to the local cause. Space will permit me to do nothing more than enumerate some of the varieties of dermatoses of pelvic origin, giving, by way of illustration, two clinical cases. Erythema, acne, pigmentation, pustules, sallowness, flushes, seborrhea, etc., are common affec- tions, made worse by conditions which exacerbate the local mis- chief, and disappearing only after the local disease is cured. Behrend, Wagner, and Steller report cases of herpes, ecchymoses, hemorrhagic nodules, etc., of uterine origin. Engelmann devotes considerable space to recording in detail histories of melasma, acne rosacea, and erysipelas. Indeed, almost any of the derma- toid diseases may, according to these writers, have their origin in the reproductive organs. The genito-reflex neuroses of the skin, unlike all others, rep- resent actual and not phantom disease. Nevertheless they differ from actual disease produced by other causes inasmuch as they fail to yield either to general or direct medication. The fact that actual skin lesions are produced in a reflex way can only be explained by the knowledge that through the vaso-motor nerves the circulatory and glandular systems are both involved. The skin "is the safety-valve of the system," and the acne of puberty, the seborrhea of menstrual irregu- larity, the flushes and sweats of the menopause, are often but external manifestations of a disturbed equilibrium, acting through the sympathetic system. Illustrative Cases. CASE XVII.-Eczema of the Face, of Five Years Standing, Cured by Operating upon the Perineum and Cervix.-æt. 35.-Married and the mother of five children. Patient came to me with a most obstinate eczema squamosum, dating from the birth of her last child, four years previously to consulting me. This remained invulnerable to both general treatment and local applications. I found upon making a pelvic examination a cervical laceration with much relaxation of the pelvic floor. Other reflex symptoms were present, including a most persistent occipital headache. Swooning and faintness just before the menstrual onset commonly occurred and the patient's friends greatly feared serious heart trouble. I removed from the cervix an incredible amount of cicatricial tissue, invading the broad ligaments on either side. The pelvic relaxa- tion was overcome by Emmet's perineal operation. For three months the patient did 214 A TEXT-BOOK OF GYNECOLOGY. not improve, but from that time on she rapidly gained in every way, and one year from the date of the operation was in perfect health. from CASE XVIII.-Acne Pustule on the Side of the Nose, Recurring with each Men- strual Period. Anteflexion, Endometritis, and Perimetritis.-Miss C Texas, 26 years of age, long afflicted with vesical pains, the result of pressure of an anteflexed uterus, menstrual suffering and great nervous depression, was much annoyed by an acne pustule which appeared for three successive menstrual periods upon one and the same place, on the right side of the nose, but ceased to come, with decided improvement in both the position of the organ and the catarrhal inflammation.—En- gelmann. GLANDULAR DISTURBANCES. Under the head of "Anomalies of Secretion," profuse salivation and urination have been referred to as symptoms indicating reflex disturbance of the parotid glands and of the kidneys. As further evidence of the sympathy existing between the repro- ductive organs and the salivary glands, it is only necessary to refer to the frequency of the metastasis of mumps to the genera- tive organs of both sexes. In the male it is the testes which become involved secondarily; in the female the ovaries, the mammary bodies and the uterus. Again parotid buboes are not unknown after ovariotomy, when no evidences of sepsis exist (Schroeder); and Goodell reports a case of swelling of the par- otid gland coming on two weeks after a trachelorrhaphy and persisting for nearly two years. Cases of diminution of the salivary secretion, of undoubted uterine origin, have been re- corded by both Engelmann and Goodell, so that, to use the words of the latter, there undoubtedly exists "a kinship of sympathy between the parotid glands and the adult sexual apparatus." The Liver.—Unfortunately we are not in possession of the same reliable data proving a direct sympathetic relationship be- tween the liver and the pelvic organs as between the salivary glands and those organs. In proof of the fact that central lesions may exert an influence upon the liver, it is only necessary to quote the old experiments of Claude Bernard, in pricking the floor of the fourth ventricle, whereby sugar was produced in the liver; or to refer to the frequent attacks of icterus caused by fright, grief, anger, etc. The exact cause of the glycosuria of pregnancy is as yet unknown, but the fact that it disappears entirely as time advances argues against organic lesion of the THE HYSTERO-NEUROSES: HYSTERIA. 215 nerve structures. It is not unreasonable to believe that uterine stimulation, either through the medulla oblongata or by direct ganglionic connection, may act upon the liver in such a way as to interfere with its glycogenic function. Be this as it may, every physician of experience has observed many cases of hepatic disturbance associated with uterine disease which disap- peared only upon curing the latter. Possibly this may be due to the fact that the treatment adopted, both general and local, improves the quality of the blood passing through the liver. Reasoning from analogy, however, it seems unwise to ignore pelvic reflexes in dealing with hepatic diseases. CASE XIX.-Hystero-neurosis of the Liver, Simulating" Gall Stones," Cured by Directing Attention to the Pelvis.—Mrs. L.—, æt. 43. Married and the mother of five children. She is a large, fleshy woman with none of the neurotic element in her make-up. For six consecutive menstrual periods she suffered from all of the symptoms of biliary colic. She would be taken suddenly with the most excruciating pains in the region of the liver, with local tenderness. Nausea and vomiting fre- quently supervened. These pains would last until the flow became somewhat pro- fuse and then gradually disappear-not infrequently lasting for twenty-four hours. The dysmenorrhea was not marked, nor were there any symptoms pointing to pelvic mischief, except a slight leucorrhea. However, after hunting in vain for gall-stones in the feces, I decided, much to the patient's disgust, to look to the pelvis. A retro- displacement was found and corrected, and in the course of two months she be- came pregnant. There has been no return of the trouble for six years. Thyroid Gland.—It is said that before and after the nuptial night the Roman matron cast a fillet around the bride's throat; if the marriage had been consummated the thyroid was found swollen on the following morning. Even in our day, says Goodell, horse breeders measure the necks of their mares before and after they have been covered, to determine whether or not they have conceived. As a sign of pregnancy the presence or absence. of swelling of the thyroid is no longer considered reliable, but as a matter of history, it shows that the ancients long ago recognized genital reflexes. I have two patients who are first apprised of conception by a swelling of the thyroid. The frequency of goiter at or about the time of puberty—often disappearing spon- taneously after menstruation is fully established-points very significantly to the probable influence exerted by the generative organs upon this gland. At any rate, in dealing with goiter in 216 A TEXT-BOOK OF GYNECOLOGY. girls and women, it is wise to bear in mind the evidence in our possession. Mammary Glands.-The mammary bodies are often highly excited by uterine disease. This is not strange when we consider the connection existing between them and the sexual organs. Indeed, they constitute a part of the reproductive system, partaking of the same physiological changes incident to puberty, pregnancy, and the menopause; therefore, patho- logical changes within the pelvis very naturally react upon them. The most common sympathetic condition is congestion, whereby the mammæ increase in size and become hot and painful. Sometimes these symptoms are purely subjective, an examina- tion revealing no perceptible alteration in the glands. Actual inflammation, even extending to the axillary glands, may supervene, and I believe that neoplasms occasionally arise from such irritation. In at least two cases I have removed the breast in suspicious enlargement, when the microscope revealed nothing but inflammatory infiltration. In both instances there was serious pelvic mischief, and the mammary irritation dated from the onset of the latter. DISORDERS OF THE NERVOUS SYSTEM. Under different heads many of the hystero-neuroses giving rise to pain and paralyses have already been considered. There yet remains to be enumerated a class of mental symptoms arising from disorder or disease of the uterus and its annexa which are known as hystero-psychoses; and a class of nervous affections characterized by paroxysms and loss of consciousness-hystero- and true epilepsy, and hysteria. The milder forms of hystero-psychoses manifest themselves in a slight melancholia with insomnia, loss of memory, fretfulness and an indescribable dread of some unforeseen calamity. In the severer types the melancholia is much more profound, and even mania may develop.* Moral perversions are likewise often * During the last six months I have seen with Dr. Barton of Ypsilanti, a case of profound suicidal mania which was entirely relieved by overcoming a badly retroflexed uterus. THE HYSTERO-NEUROSES: HYSTERIA. 217 met with, due to disturbance within the pelvis. It is high time that alienists give to this subject the attention which its impor- tance justifies. Epilepsy as a Hystero-Neurosis.*-The most important distinction to be made between a true central lesion and a ganglionic reflex is the unfavorable prognosis of the one and the favorable prognosis of the other. An accurate diagnosis is, unfortunately, often impossible before an operation or before treatment has been resorted to. It is owing to this fact that we are unable to select reflex epilepsies with unerring certainty. We are led to suspect the utero-ovarian origin of epilepsy if it recurs at each menstrual period and if we discover actual disease of these organs, but we cannot be positive until the offending organ is removed or restored to a normal condition. Even then that which, for want of a better explanation, we designate as “habit” may have so impressed itself upon the nervous centers as to continue operative after the primary lesion is overcome; or, the irritation of a nerve fiber may continue even after the diseased organ has been removed. In this there is nothing remarkable, since similar phenomena constantly occur under other circumstances. Thus, menstruation will sometimes persist in a vicarious form long after the entire uterus and its appen- dages have been removed; an epilepsy undoubtedly due to a depression of the skull will not always cease after the condition of depression has been remedied; and an imaginary pain will recur in a foot after the limb has been amputated for years. The first two illustrations are examples of " habit;" the last, an example of the continuance of irritation by the compression of terminal nerve-fibers at the point of amputation. And so, it is reasonable to believe, an epilepsy primarily due to utero-ovarian lesion may be perpetuated, even though the original lesion be cured, or the offending organ removed. I am fully aware that removal of the appendages for true epilepsy is looked upon with much distrust, and, in the light of the data at our command, justly so. I am confident, however, * v. Paper presented by the author to the International Homeopathic Medical Congress, session of 1891. 218 A TEXT-BOOK OF GYNECOLOGY. that the rapid strides of gynecology will soon define the types of epilepsy wherein the operation will prove useful. When actual disease of the appendages is demonstrable there is even now a pretty general consensus of opinion that an operation is indicated, especially if the menstrual exacerbations are marked. Unfortunately it is often impossible to demonstrate actual disease within the ovary without the aid of the microscope. The patho- logical findings in epilepsy have been most variable. Different investigators working along this line have come to as many different conclusions. One has declared that in epilepsy the weight of the brain is increased (Echeverria); another that its weight is diminished (Meynert); and still another that there exists an unequal proportion of the two hemispheres. Again, dilatation of the vessels of the superior portion of the cord; aneurysm and atheroma of the blood-vessels; sclerosis of the cornu-Ammonis; anemia of the brain; an increased quantity of the cerebro-spinal fluid; tumors and thickening of the meninges of the brain; great redness and vascular tension in the fourth ventricle (Schroeder van der Kolk); alteration of the pineal gland; abnormal thickness and abnormal thinness of the cranial bones; and fatty degeneration of some portion of the medulla oblongata, are some of the many changes found post-mortem in epileptics. Indeed, the changes recorded by pathologists are so various that it is utterly impossible to construct an explanation of the paroxysms upon a pathological basis. There yet remains a by no means insignificant number of cases in which neither the foregoing nor any other lesion, dis- coverable even by the closest scrutiny, exists. In all nervous affections characterized by paroxysms, attacks or fits of any kind, the essential feature is, according to Brown-Sequard, a morbid increase of the reflex excitability, the symptomatic manifestations depending upon "what nerve cells are altered in their vital properties." It has been pretty conclusively proved that there is no constant seat of epilepsy; and it is not unreason- able to believe that irritation in any peripheral part of the nervous system may so irritate the cells at the base of the brain, or the upper part of the cord, or both, that in time their nutri- tion will become so altered as to create a morbid excitability. THE HYSTERO-NEUROSES: HYSTERIA. 219 This is about the extent of our actual knowledge of epilepsy. The changes in these cells are more dynamical than physical, and the most powerful microscope has not yet revealed the difference between those which are perfectly normal and those which possess great morbid reflex power. (Brown-Sequard.) Both clinical observation and experimental research tend to show that these cells are located chiefly in the base of the brain. The fact that the early manifestations of an attack of epilepsy may be in very different parts of the body shows that their location must be variable. If this observation suggests any- thing it suggests the possibility of the most diverse forms of peripheral irritation exciting epilepsy. This theory is in perfect harmony with clinical observation. Literature contains in- numerable instances of epilepsies caused by injuries to nerves and organs distant from the brain.* I submit that in the light of the array of clinical evidence now in our possession we are justified in believing that irritation having its origin in the uterus or the ovaries may, under certain circumstances, excite epilepsy; and if we can detect such irritation and remove it, we may cure the disease, providing irreparable damage has not been done to the nerve centers. It is in support of this proposition that I re- cord three clinical cases of my own. With the exception of the first, none has been absolutely cured, but all have been immeas- urably benefited. The time that has elapsed since the opera- tions were performed in the several cases-two, four and seven years-tends to show that the benefit is permanent. Illustrative Cases. CASE XX.-Epilepsy Mitior (petit mal ) Cured by Operating upon the Cervix and Perineum. Mrs. C., æt. 26. Patient of Dr. E. F. Chase of Dexter, Michigan. Married, and at the time of consulting me was the mother of two children. For nearly eighteen months before coming to me she suffered from frequent attacks of petit mal, always worse during the menstrual week. While engaged in conversation she would suddenly pause in the most unaccountable manner in the middle of a *v. Medical Record, July 21, 1890, for a case of reflex epilepsy cured by the removal of a shoe-button from the left cavity of the nose; and New Orleans Medical and Sur- gical Journal, October, 1889, for a case of petit mal, with concomitant asthma, in which all symptoms were relieved by curing septal and turbinal hypertrophies, seated far back. 220 A TEXT-BOOK OF GYNECOLOGY. sentence, the expression becoming perfectly blank; in a few seconds she would again resume conversation, being conscious, however, that there had been a break in the continuity of thought. Automatic action was also interrupted, and if walking she would stop during the unconscious interval. She suffered much from a dull, heavy, occipital headache with depression and great irritability. Her memory was more or less impaired. Family history good. There was menorrhagia with dysmenorrhea and leucorrhea. Upon making a local examination I found a stellate cervical laceration, with subin- volution and much tenderness. The perineum was torn down to the sphincter mus- cle and the vaginal walls were likewise subinvoluted. I repaired the cervix and perineum in the usual manner, after which the attacks of petit mal became less fre- quent. Six months after the operation she reported herself a “new woman. Six years after there had been no recurrence of the symptoms, notwithstanding the fact that since the operation she had given birth to a third child. CASE XXI.-Epilepsy of Six Years Standing Greatly Relieved by Removal of the Appendages.—Miss J. D., æt. 23, Harrisville, Pa. Mother died of phthisis three years ago, at the age of fifty. Father living, æt. 75. When nine years of age she sustained a fall, striking on her left side, since which time there has been great sensi- tiveness in the left ovarian region. Menstruation became regular at fourteen, and although unusually nervous, nothing like an epileptic paroxysm made its appearance until she was seventeen years of age. These attacks gradually increased in frequency, so that during the three years preceding the operation she had on an average two or three every night. October 23, 1887, through the instrumentality of Dr. M. B. Snyder, she came to our college clinic for relief. At this time her general health was fairly good; she slept and ate well, and the digestive and urinary functions were normal. If it had not been for the nervous paroxysms and the pain in the left side, she would have con- sidered herself quite well. The attacks, usually nocturnal, were preceded by an ovarian aura. There was a feeling as if the left ovary were grasped and squeezed. This peculiar sensation extended up the left side of the body into the head, when she was compelled to sit down and lost entire control of herself so far as voluntary motions were concerned, but never became unconscious. If the attacks were unusually severe there was pain in the vertex; they were somewhat more frequent just before and during menstruation. The tongue had never been bitten, nor was there any history of an epileptic cry. The patient brought with her a bottle of bromid, and was profoundly under its influence; while modifying the severity of the attacks the drug had no perceptible effect upon their frequency. The memory, much to the patient's horror, was becoming seriously involved, and the besotted condition of the face, together with a peculiar, anxious look, indicated conclusively the natural tendency of the disease. A local examination showed both ovaries to be enlarged, and exceedingly sensitive. Pressure upon the left ovarian region would precipitate a convulsive attack, during which the limbs would become straightened and rigid, the hands clenched, the teeth set, and the eyes rolled back. The face would become more or less congested, but there was no frothing at the mouth. The attack would not last over thirty seconds. Unfortunately no opportunity presented itself to resort to pressure in an attack not thus induced. The case seemed one eminently appropriate for operative interference. The trouble THE HYSTERO-NEUROSES: HYSTERIA. 221 dated from an injury, and there could be no doubt that an ovarian lesion, and a serious one, existed. It is true, the paroxysms were not particularly aggravated during the men- strual period; yet a test, to my mind far more conclusive in demonstrating the con- nection existing between the ovarian lesion and the paroxysms, was present, namely, the ease with which one could be induced by ovarian pressure. The patient was for a month placed under the indicated remedy and proper local treatment, including galvanization, but only grew worse. She was very impatient to have an operation performed, having come several hundred miles for that purpose. With more indefinite local lesions I should have declined to operate without further efforts with constitu- tional and local measures. Under the circumstances, however, I performed double salpingo-oophorectomy on November 21st, 1887, in the usual manner. Both ovaries were about three times their normal size, and both full of distended follicles, the result of cystic degeneration. Hydrosalpinx was likewise present on both sides. Why, with the right ovary and tube implicated in the pathological changes quite as much as the left, the pain should be entirely confined to the left side, is a problem for our neuro-pathologists to solve. It is hardly explicable upon an anatomical basis. A change for the better seemed to come over the patient almost as soon as she regained consciousness. Her face was brighter, and that terribly besotted look had disappeared. There was hardly an elevation of the temperature until the seventh day, when it became slightly increased, owing to delay in removing the abdominal dressing. No paroxysms took place until the third day after the operation; none again for a week, after which they recurred at lengthened intervals until December 29th, when she left the hospital, the longest interval being 14 days. Improvement, in every respect, was of the most decided character. The day be- fore starting upon her long journey home, and unbeknown to the hospital attachés, she went out upon a prolonged shopping expedition and became very weary. That night she had a paroxysm, and upon her return home had two or three in frequent succession. Through a mutual acquaintance I learn that the attacks now rarely recur, are almost imperceptible when they do recur, and that she is supporting herself by hard work. CASE XXII.—Epilepsy of Fourteen Years Duration Greatly Relieved by Re- moval of Appendages.—I shall record this case in the language of my former assistant, Dr. V. D. Garwood, whose patient she was: "The patient, Miss R., æt. 45, is a woman of unusual intelligence; born of German parents. She lived in a quiet borough, of pronounced religious influence, inheriting, especially from her father, who ranked high as a scientist and musician, a sensitive, nervous system, and was pressed by him to the furthest limit in her education; on the other hand she was brought up in the Medean and Persian routine of German housewifery. When dysmenorrhea appeared it was regarded as too trivial for treatment, until epilepsy developed. "As a child she was healthy until eleven, when she had scarlet fever, and for years after was subject to enuresis. Pleurisy followed some time after scarlet fever. At seventeen, eczema upon the hands appeared, lasting about a year, which was cured by outward application. "Between eighteen and twenty years of age she suffered frequently from asthma, which appeared every July. While engaged in teaching a year or two later a violent attack of acute pain and cramps in the stomach occurred, followed by a jaundiced 222 A TEXT-BOOK OF GYNECOLOGY. condition. This attack was supposed by the physicians in attendance to be due to a round perforating ulcer of the stomach. "From that time until twenty-nine years of age she seemed to be in fair health, with the exception of dysmenorrhea, to which no attention was paid. The first spasm—a very slight one-occurred in August, 1875. These continued during the fall, and were accompanied by an unpleasant noise in the head. She did not fall or lose consciousness; the slighest sound was increased to an unendurable noise in her head. Her attendants approached her on tip-toe to give her a drink or to fan her. Toward Christmas of that year the unconscious attacks began at night, with the petit mal during the day. "At this stage of her trouble the most eminent physicians of Philadelphia were consulted-Drs. Weir Mitchell, Goodell, and others. After some time the mania epileptica developed; this, however, after the discontinuance of the bromids. In April, 1885, she had an attack of acute rheumatism, in which hyperpyrexia was marked. After this there was complete exemption for six months from the nervous attacks, but overwork and intense strain upon the emotions brought them on again with renewed violence. “She came under my care in August, 1888. For the preceding year one week of each month-her menstrual week-had been a perfect blank to her, owing to the frequency of the paroxysms. She had often bitten her tongue and had injured her- self severely by falling. Observing that the periodicity of the attacks was that of the catamenia, I consulted Dr. J. C. Wood, who, in May, 1889, performed salpingo- oöphorectomy. From that time until August there were no spasms. In October there was a severe outbreak, but since that time until January, 1891, only slight at- tacks every two months, with excellent health in the intervals. She has returned to society and to her literary work. Her memory is being rapidly restored, and she en- joys life as never before since her illness."* In this case I found great tenderness of the ovaries but no perceptible enlargement. After removal they were examined by Prof. Heneage Gibbes, the pathologist of the University, who reported hyaline degeneration. Certainly if such a thing as a "menstrual epilepsy" exists, this was a case, and under the circumstances I had no hesitancy in removing the appendages. She came to me after passing through the hands of some of the ablest physicians of both schools, and I knew that all ordinary resources had been exhausted.† *This patient's improved condition remained permanent for two years, when she had a paroxysm in an out-house and died from strangulation. † I have succeeded, in a case referred to me by Prof. D. A. MacLachlan, in reducing the number of paroxysms from two or three a month to one in six months, simply by divulsing the cervix and the rectum. There was marked obstructive dysmenorrhea and obstinate constipation, both of which were entirely cured by the operation. The epilepsy was of twenty years duration. THE HYSTERO-NEUROSES: HYSTERIA. 223 The extent of the disease is hardly a reliable criterion on which to base the necessity of operative interference, for we know that a slight amount of disease will in one woman pro- duce serious reflex symptoms, whereas, in another, most ex- tensive lesions will produce no disturbance whatever. It is necessary, therefore, under all circumstances in dealing with neuroses, to recognize types of constitution as well as the char- acter of local lesions. Indeed, in descending the pathological scale, a point may be reached where, instead of actual disease, there is simply functional disturbance which must be recognized as a causative factor. I believe, however, that we are rarely justified in removing the appendages unless there is pretty con- clusive evidence of local disease. If such evidence be forth- coming; if the fits are intimately associated with the menstrual function; if the aura starts from the ovarian region; if there are no evidences of serious disease of the nerve-centers; if the health and mind are failing and the patient is rapidly approaching a state of chronic invalidism or insanity; and, above all, if all ordinary measures have been exhausted and internal medication faithfully tried, I believe that the gynecologist is justified in resorting to any reasonable measure promising some hope of relief. THE HYSTERICAL PAROXYSM. A dissertation devoted to the hystero-neuroses and hysteria would be incomplete without a brief description of the hysterical paroxysm. However, were all of its manifold variations included in this description another chapter would be necessary. I shall therefore refer to the most salient features only. An aura starting from the affected ovary frequently precedes the attack. In the milder forms there is accelerated, irregular, and often interrupted respiration. Spasms of the extremities, rhyth- mical in character, accompany the perverted respiration. In a few minutes the attack ceases, but others may follow in rapid succession. Consciousness is rarely lost, though in the more severe forms the loss of consciousness may be profound. Dis- tortion and fixation of the trunk and extremities are caused by the tetanic convulsions. The respiration becomes slow and ster- torous, and there is frothing at the mouth. The bowels are fre- quently greatly distended with gas. These symptoms, together 224 A TEXT-BOOK OF GYNECOLOGY. with the alternate tonic and clonic character of the convulsions, have given rise to the term hystero-epilepsy. Before and after the attacks there is often hemianesthesia and hyperesthesia. Relaxation succeeds tetanic muscular contraction, and this is followed in due time by exaggerated muscular phenomena. Emotional symptoms soon supervene. Anger, resentment, joy, grief, and apprehension are alternately depicted on the counten- ance. Lascivious manifestations are not infrequent. There may be hallucinations, during which the patient sees all sorts of disagreeable objects and things. Then comes contrition, and after it, recovery. Treatment. The physician must assume absolute control of the room and its inmates. Sympathizing and excited friends should be excluded. Slight hysterical seizures of an emotional character can often be controlled by the indicated remedy, or by inhalations of ammonia, or of nitrite of amyl. When the par- oxysm is fully developed more radical measures are necessary. Most authorities recommend douching the head and face with cold water. This is a successful method of treatment, but a difficult one to apply without wetting the clothing. A few tea- spoonfuls of water poured into the mouth or nostrils will often accomplish the same purpose, and should be first tried. It acts by stimulating the respiratory centers. Dr. Hare recommends closing the nostrils and mouth for fifteen or twenty seconds with a towel. Chloroform or ether inhalation is very effective, and one of the best methods of controlling an attack. Ice-water injected into the rectum may be tried. Cruveilhier and Ashwell recom- mend that cold water be injected into the stomach. Cutaneous faradization has been found useful. It is accomplished by placing the two electrodes anywhere from the neck to the hand, or on the two hands. Finally, Gowers * uses, when all other measures have failed, a hypodermic injection of a twelfth or sixteenth of a grain of apomorphia with invariable success. As soon as nausea is excited the paroxysm ceases, and the patient regains consciousness immediately upon vomiting, which occurs in six or eight minutes after the injection. Pressure over the region of the ovaries, according to the * "Diseases of the Nervous System," p. 1329. THE HYSTERO-NEUROSES: HYSTERIA. 225 method of Charcot,* is a simple, harmless, and often a most effectual procedure. It is accomplished by placing the patient in a horizontal position on the floor or mattress and pressing the closed hand or fist into one or both iliac fossæ. Much force is at first necessary to overcome the contraction of the abdominal muscles. If successful, the patient soon makes numerous and noisy attempts to swallow, when consciousness returns. The phenomena of the seizure disappear in from two to four minutes. Therapeutics. Moschus.-Constriction of the chest, frequent swooning, great anguish with fear of death; HYSTERIA SIMULATING TETANIC SPASMS; globus hystericus; great desire for beer or brandy. Chamomilla.-Irritable, peevish, impatient; great tendency to quarrel, to speak in an obstreperous manner; moaning and wailing during sleep. Hyoscyamus. Jerking and twitching in the spasms; convul- sions resemble epilepsy; much silly laughter and foolish action; she is disposed to uncover herself and go naked. Caulophyllum.—HYSTERICAL CONVULSIONS DURING DYSMEN- ORRHEA; hysteria in anemic and greatly debilitated patients; spasmodic, intermittent pains in the bladder, stomach, groins, chest and limbs. Platina.-Self-exaltation and contempt for others; a strange titillating sensation extending from the genital organs up into the abdomen; spasms, with wild shrieks; horrifying thoughts; menses in excess, dark and thick. Nux Moschata.-Frequent and sudden change of mental symptoms; excessive tendency to laughter; enormous distention of abdomen after meals; EXCESSIVE DRYNESS OF MOUTH AFTER SLEEPING. Lachesis.-Sensation as if a lump were rising in the throat; CANNOT BEAR THE LEAST PRESSURE EXTERNALLY ON ANY PART OF THE BODY; AGGRAVATION AFTER SLEEPING. Consult:-ANACARDIUM, AURUM, asafetida, GELSEMIUM, cactus grand., lilium tigr., stramonium, ZINCUM, tarantula, valeriana. * "New Sydenham Society of Charcot's Lectures," p. 27 15 CHAPTER XVI. MENSTRUATION AND ITS DISORDERS. PHYSIOLOGY OF MENSTRUATION; AMENORRHEA General Considerations.-The anomalies of menstruation cannot be intelligently studied without a familiarity with its physiology. As to the cause of menstruation there is much that is yet uncertain; the phenomena belonging to the function are, however, well known; and, from a practical standpoint, it is these which most concern the physician. Definition. Menstruation may be defined as a periodical discharge of blood from the uterine cavity, recurring at regular intervals between puberty and the menopause, except when physiologically interrupted by pregnancy and lactation. Puberty begins in this climate at the average age of thirteen, and climac- teric changes are usually inaugurated at about forty-four. The age of puberty is influenced by climate, habits, idiosyncrasies and disease. It occurs earlier in warm than in cold climates, and in large cities than in rural regions. * It is delayed in cer- tain families until the age of sixteen, seventeen or even twenty years, without any perceptible ill-effect; and it is frequently de- layed for an indefinite time by some constitutional bias, notably tuberculosis. The symptoms of approaching puberty are very characteristic. The habits of girlhood are discarded for those of retiring womanhood, the figure develops, and the breasts enlarge; coincident with these changes, hair appears upon the mons Veneris. The symptoms of perfectly normal menstruation are objective rather than subjective. Nevertheless, there are few girls or * Lutaud (Bulletins et mémoirs de la Société obstétricale et gynécologique, Paris, December, 1890), reports the case of a girl who began to menstruate at seven years and two months. The patient was well formed and healthy. 226 MENSTRUATION AND ITS DISORDERS. 227 women who do not suffer just before the advent of the flow from a feeling of uneasiness or weight in the pelvic organs, and frequently there is an unpleasant sense of fulness in the breasts. These symptoms are particularly marked at the first menstrual period, and are often accompanied with decided nervous phe- nomena. Occasionally the first knowledge of the approaching period is the presence of the flow. A normal period continues from two to eight days, and the quantity of blood lost varies from two to nine ounces (three to twelve napkins). Either extreme may be perfectly normal, depending upon the temperament and habits of the menstru- ating woman. The average duration is about four days, and the average quantity of blood lost, five ounces. During the inva- sion the discharge is pale; during its persistence it becomes darker, is non-coagulable, and consists of red and white blood corpuscles, granular corpuscles, and mucous globules com- mingled with epithelium from the uterine, cervical, and vaginal cavities; during its decline it again becomes pale. Unless the flow is excessive there is no clotting, for the vaginal secretion preserves its fluidity. Theories.-The ovarian theory of menstruation, advanced and advocated by Costé, Gendren, Bischoff, Negrier, and Pflüger, has long been, and still remains, the classical one. According to this theory, ovulation and ovarian irritation are responsible for menstruation. When oophorectomy became a common operation, it was observed that menstruation sometimes per- sisted even after the ovaries were removed; and that the func- tion was more surely, although not invariably, abrogated if the Fallopian tubes were removed with them. Lawson Tait, who was the first to observe this fact, promulgated the so-called Fallopian theory of menstruation. He maintains that the func- tion of menstruation is not ruled by the ovaries, and presents the following reasons why he believes that the starting point is the Fallopian tubes :— (1) Pain when the tubes are occluded; (2) the first appear- ance of menstrual fluid in the tubes; (3) the continuance of menstruation after the removal of the ovaries; (4) the arrest of menstruation after the removal of the tubes. 228 A TEXT-BOOK OF GYNECOLOGY. As counter evidence to the Fallopian theory and in support of the ovarian, the following observations are presented :—* (1) When the ovaries are congenitally absent menstruation is also wanting; (2) when the ovaries are removed early in life the same result is apparent; (3) when the ovaries are removed after puberty menstruation generally ceases; (4) all the secondary sexual characters of the female are dominated by the ovary, and menstruation is one of these. The arguments set forth to substantiate these two theories of menstruation—the Fallopian and the ovarian—are based upon certain phenomena which are by no means invariable. It may be said that, while menstruation does sometimes persist after the removal of the ovaries without the tubes, this is only exceptionally the case; and it cannot be maintained that the function always ceases after the ovaries and tubes are both removed, for a number of authentic cases are now on record in which both appendages have been removed without accom- plishing this end. That the first appearance of the menstrual blood in the human female is always in the tubes is hardly sus- ceptible of proof. On the other hand it must be admitted that menstruation occurs at a period of life when ovulation is most active; but that there is a causal relation existing between the menstrual flow and the escape of the ovule, while probable, has not yet been conclusively proved. A still more modern theory is that of Campbell.† Campbell believes that the menstrual rhythm is initiated by a nervous rhythm dependent upon nervous structures. "Just as there is a rhythmically pulsating respiratory and cardiac center, so there is a rhythmically pulsating sexual center which furnishes fibers both to the ovaries and to the uterus, those of the latter passing, for the most part, along the Fallopian tubes, but some few to the uterus directly." Campbell further believes that ovulation is an essential, though not an indispensable, factor of the menstrual rhythm. This hypothesis will at least explain the following facts as set forth :— * London Lancet, December, 1888. † Annual of Universal Medical Sciences, 1890. MENSTRUATION AND ITS DISORDERS. 229 (1) The periodic flow sometimes continues after the removal of the ovaries; (2) the function is generally abrogated by the removal of the tubes; (3) occasionally it continues after both the ovaries and tubes have been removed, just as a reflex epilepsy sometimes continues after the source of irritation has been removed. * Neither is there a general consensus of opin- ion regarding the source of the hemorrhage, and the changes which the endometrium undergoes. J. Bland Sutton † has made a series of observations in the quadrumana, and has also examined the uteri of some young women who died during menstruation. From these observations Sutton is led to believe that the disintegration of the mucous membrane is limited to the superficial and glandular epithelium, and that the mucous membrane of the Fallopian tubes remains unaltered. Dr. Arthur W. Johnstone affirms “that the functions of the ovary and the uterus are separate and distinct, and that the endometrium is the real organ of menstruation." Dr. John- stone's investigations go to prove that the loss of substance in the menstruating uterus is limited to the epithelial lining of the mucous membrane. Kundrat and Engelmann also believe that only the superficial layers of mucous membrane are removed. In marked contrast to the foregoing views are those of Dr. John Williams,‡ of London, who maintains that "uterine con- traction drives the blood from the muscular walls into the mucous membrane; the vessels of this membrane, having undergone fatty degeneration, give way, and extravasation of blood results. This extravasation takes place always near the surface, for in that situation the degenerative changes have most advanced. The rush of blood into the vessels of the mucous membrane expels the contents of the glands, together with the greater part of their lining epithelium. When * The still more recent observations of Robinson are in harmony with this theory. Robinson believes that menstruation is inaugurated by tubal motion due to ganglia situated in the uterine walls and along the tubes, which are intimately connected with the ovaries.-New York Medical Journal, January, 1891. † Brit. Gynec. Journal, 1886. Obstetric Journal, London. 230 A TEXT-BOOK OF GYNECOLOGY. hemorrhage has taken place into the membrane it undergoes a rapid disintegration, and becomes entirely removed." Williams believes that a new mucous membrane is formed from the muscular wall of the organ. In the light of present data this is hardly probable. Leopold denies the existence of fatty degeneration, and believes that the bleeding is due to the peculiar arrangement of the blood-vessels in the endometrium. There exists, according to this author, a disproportion between the arterioles that supply the capillaries of the uterus, and the veins that receive the blood -the arterioles being relatively larger; as a result a sudden afflux of blood to the uterus is not carried off by the veins and the capillaries rupture. In the process of disintegration only the superficial layer of the mucous membrane is removed. Möricke, basing his observations upon curettings from living menstruating women, asserts that "during menstruation the mucous membrane disappears neither partially nor fully." It will be seen by the foregoing that much pertaining to the physiology of menstruation is as yet unsettled. I have deemed it best to present in a condensed form the more prominent theories. I shall not venture an opinion of my own, further than to add that Campbell's theory as regards the cause of the periodical flow of blood termed menstruation, and Leopold's theory as regards the changes which the uterine mucous mem- brane undergoes, as the result of this flow, seem to me the most reasonable. AMENORRHEA. The term amenorrhea signifies an absence or stoppage of the menstrual discharge, due to causes other than physiological. It may be primary (emansio-mensium) or secondary suppressio- mensium). In both of these forms there is non-secretion. Reten- tion of the flow is also classified under the head of amenorrhea, though the causes responsible for the absence of the discharge are radically different from those giving rise to the primary and secondary forms. Amenorrhea is physiological during preg- nancy and lactation. Primary Amenorrhea. (Emansio-mensium).—In the primary form of amenorrhea menstruation has never occurred and MENSTRUATION AND ITS DISORDERS. 231 puberty, for some reason, is delayed. The causes for such delay are variable and must be carefully sought for. Probably some form of constitutional bias, anemia, tuberculosis, scrofulosis, or rickets, is oftener responsible for it than anything else. Such being the case the patient's vitality is conserved by the amenor- rhea. Again the menstrual function may be held in abeyance by misdirected mental effort and insufficient exercise. Con- genital defects involving the uterus, ovaries, Fallopian tubes, or indeed, any of the sexual organs, are not infrequently responsible for the non-appearance of the menses. The symptoms of primary amenorrhea are those of delayed puberty. The changes incident to normal puberty are wanting: the breasts do not enlarge, the figure remains undeveloped, and no hair appears upon the mons Veneris. Molimina may or may not be present: if present many of the symptoms of menstruation occur, minus the flow; if absent, and the cause is due to one of the enumerated constitutional disorders, the symptoms of the latter will stand out prominently. Let it be remembered that in these instances the amenorrhea is the effect and not the cause of the constitutional malady. The delay of the function not infrequently gives rise to nervous phenomena, especially when there is an effort on the part of the system, as indicated by the molimina, to establish it. Hysteria often occurs, and the nervous perturbation may result in chorea. Neuralgia is not an uncommon symptom, especially if anemia or chlorosis is marked. The diagnosis of primary amenorrhea is not difficult. It ought not to be mistaken for physiological amenorrhea due to preg- nancy, and yet such mistakes have been made. In primary amenorrhea the evidences of delayed puberty—the diminished size of the uterus, the undeveloped mammæ and figure-and the absence of abdominal tumor, all argue against pregnancy. It must not be forgotten that conception is possible before menstruation: from a practical as well as a medico-legal stand- point this fact is important. Secondary Amenorrhea. (Suppressio-mensium).—In secon- dary amenorrhea the menstrual function has, for a longer or shorter period, existed, but owing to some cause or causes it 232 A TEXT-BOOK OF GYNECOLOGY. has become suppressed. In acute diseases-phthisis, anemia, and chlorosis-the suppression is not undesirable, for by means of it the patient's strength is conserved. Indeed, menstruation should not occur with an anemia at all marked; if it does, and the flow is profuse, the physician is justified in suspecting that the depravity of the blood is secondary to the menstrual excess. In such cases an effort should be made to induce amenorrhea, either partial or complete, by directing attention to the endome- trium, for, in many instances, the latter will be found abnormal. Wylie observes that if amenorrhea occurs during the period of development of the sexual organs their growth is often perma- nently affected by it. The inflammatory diseases of the pelvis may likewise produce amenorrhea by leaving in their train lesions of the ovaries and tubes; oftener, however, such lesions result in menorrhagia. There are certain women, healthy in all other respects, who suffer from suppression upon the least irregularity. Change of climate or altitude, a sea voyage, or the slightest exposure, is quite sufficient to induce amenorrhea. Usually it is only temporary, and in due time the menstrual equilibrium is restored; occasionally the system becomes so profoundly impressed by the suppression that the amenorrhea remains per- manently. Those who have to deal with immigrants coming to this country state that amenorrhea frequently results from the sea voyage and climatic changes combined. The symptoms of secondary amenorrhea depend in no small degree upon the suddenness of the suppression. In acute sup- pression there is marked disturbance of the nervous and vascular systems, manifesting itself in increased arterial tension, palpita- tion of the heart, headache, neuralgic pains in various parts of the body, and, not infrequently, hysteria. The local distress is sometimes very great, the pain being sharp and darting, or cramp-like. Occasionally the vascular excitement is preceded by a chill, and the congestion induced may pass into serious inflammation. When amenorrhea is developed gradually, the symptoms are less violent, though often of most serious import. Prostration, lassitude, indigestion, constipation, and cardiac oppression, one MENSTRUATION AND ITS DISORDERS. 233 or all, make their appearance in due time. The symptoms of the disease which is responsible for the non-performance of the function, anemia, phthisis, etc.,-force themselves upon the attention of the physician. Under all circumstances pectoral symptoms occurring in connection with amenorrhea demand serious consideration. Diagnosis.-This form of amenorrhea is easily mistaken for pregnancy. The subjective symptoms are much the same in both instances: nausea, vomiting, morning sickness, mammary pains, etc., may result either from pathological or physiological suppression. During early pregnancy the increased size of the uterus is so slight as to make even the most deft diagnostician uncertain regarding its contents. If the patient is untruthful, and denies the possibility of pregnancy, time is the only abso- lute test. After the third month the diagnosis can usually be made with a fair degree of certainty. Retention of the Flow.-Amenorrhea due to retention is the result of some interference with the exit of the menstrual discharge after it has been secreted. The cause of obstruction may be congenital or acquired. An imperforate hymen is the most frequent congenital cause, though the menses are sometimes retained because of atresia of the vagina higher up. Usually, however, when the vagina is congenitally absent the menstrual function is held in abeyance. The acquired causes oftener result from child-bearing, the sequelæ of inflammation and sloughing. Operations upon the cervix may also result in atresia. Tumors, polypi, flexures and coagula may give rise to temporary retention. Symptoms.-Retention of the menses may and usually does give rise to much suffering. Attacks of pain recur at regular intervals, with all the usual symptoms of menstruation, except the flow. The pain is of a bearing-down character, com- ing and going at variable intervals, and reaching its climax after some hours duration. It then gradually subsides and finally dis- appears to recur again at the next period. There is often marked general disturbance during the paroxysm of suffering which manifests itself in headache, increased arterial tension, nausea and vomiting, pain in the back and limbs and nervous 234 A TEXT-BOOK OF GYNECOLOGY. phenomena of various kinds. Hysterical convulsions are not infrequent, and even epilepsy may develop. In due time the uterus becomes distended with the products of menstruation, giving rise to a tumor in the hypogastric region. Diagnosis.-The regular recurrence of molimina correspond- ing to the menstrual cycle, and the gradual formation of a tumor in the uterine region, together with the absence of the menstrual discharge externally, will lead the physician to sus- pect the nature of the case. The reflex symptoms of pregnancy may be present, but a local examination will reveal the cause of the difficulty. Such an examination may necessitate exploration through both the rectum and bladder in order to determine the presence or absence of the uterus and annexa. The prognosis of amenorrhea depends entirely upon its cause. Of the various constitutional ailments giving rise to it anemia is the most amenable to treatment. If the result of acute disease the system usually rights itself in due time. Tuberculosis is, of course, always of serious import. Of the anatomical causes imperforate hymen is the most easily dealt with. Congenital absence of the uterus or ovaries makes a cure impossible; if due to deficient development only, the prog- nosis will depend upon the presence or absence of molimina. When atresia of the vagina is responsible for the retention it is possible, by surgical measures, to liberate the pent-up discharge and to restore the canal to its normal condition; when it is con- genitally absent, however, an attempt to form a vagina usually results in failure. THE TREATMENT OF AMENORRHEA. Let it be remembered that amenorrhea is in many instances but an expression of some systemic trouble toward which the treatment should be directed. Anemia, chlorosis, nervous pros- tration, tuberculosis, etc., are the real diseases of which the amenorrhea may be but a symptom. The general and special measures appropriate for these several diseases should be brought into requisition. Under all circumstances fresh air, sunlight, exercise, and good food are of the greatest utility. In short, the several measures suggested in the chapter devoted to the MENSTRUATION AND ITS DISORDERS. 235 General Treatment of Gynecological Diseases should be applied. In acute suppression an effort should be made to restore the discharge, if this can be accomplished by measures which are not injurious. Of first importance in accomplishing this end is the indicated remedy. A hot foot or sitz bath is a most useful adjuvant, as is also the hot douche. The latter is particularly indicated if the evidences of local congestion are at all marked. Failing with these several measures, after a few hours trial, it is not best to attempt longer to restore the flow by the use of hot water. The indicated remedy should, however, be continued until the system is put right. The use of so-called emmena- gogues is, under all circumstances, to be discouraged. When amenorrhea or scanty menstruation is due to imperfect development of the sexual organs, an effort should be made to promote their development. This can be done in various ways, but undoubtedly the most useful of all agents known at the present time for accomplishing this end is electricity. The time and technique of application are given in detail in the chapter devoted to that subject. Patience and persistence are required in using electricity for this purpose, but so long as nature con- tinues to assert herself by exciting molimina, there is hope of bringing on the flow. The introduction of the uterine sound and the use of the galvanic stem pessary also stimulate the uterus in a mechanical way. There can be no objection to the careful use of the sound, but the intra-uterine stem is an instru- ment always to be resorted to with the utmost caution. Therapeutics. Calcaria carb.-LEUCOPHLEGMASIA, with malnutrition and disturbance of digestion; face pale and bloated, with blue rings around the eyes; oppression of the chest tending to tuberculo- sis; COLD HANDS AND COLD FEET; amenorrhea with anasarca from working in water. Ferrum.-ANEMIA; great nervousness and debility, with FIERY REDNESS OF THE FACE ON THE LEAST EXCITEMENT; palpita- tion of the heart; paleness of all the mucous membranes; diar- 236 A TEXT-BOOK OF GYNECOLOGY. rhea, with undigested food; want of breath when moving or ascending; pressure in the stomach and head. Arsenicum.-White, waxy paleness of the face, and GREAT DEBILITY; corrosive leucorrhea; frequent paroxysms of faint- ing; painful lienteria, followed by much prostration. Pulsatilla.-Especially useful at the age of puberty; sup- pression from getting the feet wet; menstrual suppression com- plicated with ophthalmia; hemicrania, with stitching pain in face and teeth; painful lumps in the breast, extending to the arms. (Guernsey.) "When in girls of mild disposition puberty is unduly delayed, or the menstrual function is defectively or irregularly performed; when they grow pale and languid, and complain of headache, chilliness, and lassitude, pulsatilla (with or without fer- rum) is a most excellent remedy."-Hughes.* Kali carb.-Swelling of the EYELIDS; disposition to phle- bitis; stiffness and pain in the small of the back; aggravation of all symptoms at two or three o'clock in the morning. Graphites. After pulsatilla; occasional show of menses, which are very pale and very scanty, with abdominal pains and pain in the limbs (Guernsey); GRAPHITES IS IN CLIMAXIS WHAT PULSATILLA IS IN YOUTH (Lilienthal). Sepia.-Yellow or greenish leucorrhea accompanied by much itching of genital organs; amenorrhea at age of puberty or later; PAINFUL SENSATION OF EMPTINESS AT PIT OF STOMACH ; brown spots on chest and yellow saddle across bridge of nose. Aconite.-Amenorrhea from taking cold or getting feet wet, with congestion of the head and chest; suppression from fright or vexation. Particularly useful in acute suppression in young girls of sanguine temperament, and who lead a sedentary life. Belladonna.-ACUTE SUPPRESSION WITH GREAT CONGESTION * PULSATILLA LILIUM TIGRINUM. A Comparison.- Lilium, like Pulsatilla, causes scanty menses, but the former has irritable mood, wants to die, and yet knows not why; solicitude about health; absence of feeling in the head with amenorrhea; longs for meat; diarrhea hurries her out of bed in the morning. Pulsatilla has gen- tle, tearful mood; wants to die, but fears it; solicitude about health and salvation; mania with amenorrhea; averse to meat; diarrhea after midnight. Remission, in lilium, forenoon; in pulsatilla, midnight until noon (except diarrhea).—American Journal of Homeopathic Materia Medica. MENSTRUATION AND ITS DISORDERS. 237 OF THE FACE AND EYES AND THROBBING OF THE CAROTIDS; intolerance of light or noise; bearing-down pains as if the con- tents of the abdomen would issue through the vulva. Secale corn. There is a continual, long lasting, forcing pain in the uterus at the menstrual nisus; leucorrhea brownish and offensive, resulting from weakness and venous congestion. Sabadilla.--Menses are suppressed immediately on their appearance, appearing again sooner or later, to be again sup- pressed. Apis mel.-Amenorrhea with bloated, waxy face; ovarian irritation with stinging pains; cardiac distress. Gelsemium.—Amenorrhea with a dull, heavy headache; vertigo, with disturbed vision; darting, twitching, neuralgic pains in the face. Sulphur.-Great congestion of the pelvic organs and of the head; coldness of the feet, or BURNING OF THE SOLES OF THE FEET at night in bed; FLUSHES OF HEAT; hemorrhoids; chronic inflammation of the eyelids and a general eruptive tendency. Platina.-PAINFUL SENSITIVENESS and continual pressure in region of mons Veneris and genital organs; frequent sensation as if the menses would appear; amenorrhea with induration of the uterus and co-existing ovarian irritation. Aurum.-Amenorrhea with prolapsus uteri and MELANCHOLIA ; thick, white leucorrhea, with burning and smarting of the vulva. Opium.—Amenorrhea from fright; IRRESISTIBLE DROWSI- NESS; great heaviness of the head with fainting on rising. Dulcamara.-Menses suppressed by cold; mammary glands engorged and hard; rash before menses. Consult:-Causticum, mag. carb., cimicifuga, borax, mer- curius, nux vom., xanthoxylum,* and zincum. * Xanthoxylum in Amenorrhea.-A servant girl, during her catamenial period, scrubbed the floor in naked feet. The flow ceased at once and there was no return. At the end of six months she became emaciated, coughed terribly, with dirty, gray expectoration, pale face, night sweats, etc. Thought she had consumption and gave up work. Xanthoxylum brought on the menses in four days and she recovered rapidly. It is now five months since, and she has menstruated regularly, and has so far recovered her health that she has resumed her labor again.-DR. J. C. WILLIAMS, U. S. Med. and Surg. Journal, October, 1871. CHAPTER XVII. MENSTRUATION AND ITS DISORDERS (Continued). UTERINE HEMORRHAGE. General Considerations.-Hemorrhage from the uterus must be looked upon as different from hemorrhage proceeding from any other organ of the body, for the uterus is normally subjected to the greatest variations of vascularity. Again it is necessary, in order to determine whether or not the menstrual discharge is excessive in a given case, to consider the age and idiosyncrasy of the patient, as well as the effect which the discharge has upon the system. One woman can, with impunity, lose an amount of blood which would be ruinous to another. • Hemorrhage from the genital canal does not always proceed from the uterus. It may have its origin in some lesion of the vagina or the urethra, or indeed, a supposed uterine hemor- rhage may come from the rectum. Women are sometimes careless observers, and this fact should be borne in mind. The term menorrhagia indicates the menstrual origin of the hemorrhage and signifies excessive menstruation; the term metrorrhagia signifies that the hemorrhage either occurs during, or is prolonged into, the inter-menstrual period. This division is convenient and in harmony with clinical observation. For the purposes of study, however, it is more practicable to deal with uterine hemorrhage per se, whether occurring at the menstrual or the inter-menstrual period. The various causes giving rise to abnormal hemorrhage from the uterus may be classified as follows: 1. Constitutional, (a) Hemorrhagic diathesis; (b) Purpura; (c) Tuberculosis; (d) Bright's disease; (e) Syphilis. 238 MENSTRUATION AND ITS DISORDERS. 239 2. General,. 3. Nervous, . [ (a) Lactation; (b) Pelvic congestion due to disorders of the heart, liver, lungs, and stomach; sedentary habits sexual excesses; and ovarian disturbances. (c) Malaria; (d) Lead poisoning; (e) Pyrexial disorders. {(8) Centric; Reflex. (a) Carcinoma; 4. Malignant lesions, . { (b) Sarcoma. (a) Fibroma and polypi; 5. Non-malignant lesions, (b) Inflammatory; 6. Accidental, . { 7. Pregnancy, 8. Climacteric. (c) Subinvolution. (a) Chronic uterine inversion; (b) Hematocele ; (c) Uterine displacements. (a) Abortion; (6) Placenta previa. Constitutional Causes.-The various constitutional diseases predispose to hemorrhage by inducing blood changes. In the so called hemorrhagic diathesis, purpura, tuberculosis, Bright's disease, and syphilis such changes have taken place, and the blood readily passes through the lining membrane of the womb. Long continued hemorrhage, the result of some local disease, wil in due time so defibrinate the blood as to predispose to hemorrhage from various channels of the body. In dealing with the hemorrhagic diathesis it is not always pos- sible to detect the constitutional bias. The victims of this diathesis are known as "bleeders," and every, surgeon of ex- perience has learned to dread them. In all other respects the patient will seem to be perfectly well, but the slightest cut or injury will bleed unduly. It is not surprising that the menstrual discharge in these patients should be great enough to demand attention. Tuberculosis gives rise to amenorrhea oftener than to menor- rhagia. Nevertheless tubercular patients do sometimes flow excessively; and the disease may be precipitated by an exag- gerated menstrual discharge which in time reduces the vitality of the patient to such an extent as to make her an easy prey to phthisis. In those cases of menorrhagia in which there is a 240 A TEXT-BOOK OF GYNECOLOGY. predisposition to tuberculosis it should be the aim of the physi- cian to conserve the patient's strength in every possible way. In Bright's disease the concomitant symptoms,-albuminuria, anasarca, edema, etc.,-will lead the examiner to look to the kidneys for the cause of the mischief. I have more than once met with uterine hemorrhage due to syphilis, which yielded upon adopting an anti-syphilitic régime. General Causes.-Of the general causes, excessive lactation, malaria, lead poisoning, and the pyrexial disorders, all induce hemorrhage by their degenerating influence upon the blood. Menstruating women ought not to nurse their children, for there are few constitutions strong enough to permit of the double drain. This is especially true when there is a predispo- sition to some of the foregoing diathetic troubles. Lactation may also excite hemorrhage through reflex irritation. Malaria undoubtedly predisposes to pelvic congestion, and it may be impossible to control a uterine hemorrhage while the patient remains in a malarious climate. It has been frequently observed by English physicians that women who have lived for any length of time in India are usually victims of menorrhagia. Undoubtedly the tropical temperature, as well as the malaria, is a potent factor in these cases. The influence exerted by lead poisoning upon the uterus, and its power to produce uterine hemorrhage, has not received the attention from therapeutists commensurate with the import- ance of the subject. I was first impressed with the homeopath- icity of plumbum in menorrhagia by the experience of one of the provers of the drug-a most intelligent lady practitioner— whose menorrhagia dated from a proving made ten years previously. Later clinical experience has confirmed this homeo- pathicity in a number of instances. Benson Baker of Eng- land.(Obstetrical Transactions, Vol. 1), and Paul of France, have both called attention to this subject." * If parents who suffer from lead poisoning have children, we may naturally expect that in their early years they will suffer from certain diseases analo- gous to, or participating in, the general cachexia of lead poisoning; and if they did it would not be unreasonable to consider these children as suffering from hereditary lead poisoning. From M. Paul's paper it appears that lead poisoning amongst MENSTRUATION AND ITS DISORDERS. 241 Pelvic congestion due to the several conditions enumerated is a prominent factor in causing and keeping up uterine hemorrhage. If these causes continue active, the best directed treatment will fail in its object. Luxurious and sedentary habits are pernicious under any circumstances, but particularly so when there is a tendency to flow excessively. Sexual excesses are equally harm- ful, and it is sometimes exceedingly difficult to learn that such excesses are practised. One of the most obstinate cases of menorrhagia with which I have had to deal occurred in a girl of twenty, who was a confirmed onanist. Many married women are the victims of sexual excess or sexual irregularities, and a temporary marital separation may be necessary before a cure can be accomplished. If such excesses are associated with the other enumerated causes, especially ovarian irritation, the case is indeed complicated, and for its management no little tact and skill will be required. Nervous Causes.-That nervous influences may affect the uterus and its functions for good or for evil has already been shown. They may either emanate from the nerve centers, or exert their influence in a reflex way. Undue emotional excite- ment is the most frequent centric cause, and occurs oftener in nervously prostrated patients who are subject to hysterical manifestations. Spinal lesions-functional exhaustion, irrita- He says: women, and even amongst men, causes the death of the fetus in utero. 'The first time my attention was drawn to the subject was in the month of February, 1859, when a woman that worked at cleaning printers' type applied at the Hospital Necker, suffering from menorrhagia. Coupled with this menorrhagia she also had the symptoms of chronic lead poisoning. I learned from her that, previous to her present employment, she had been delivered of three healthy children at full term, still alive; but that since her employment as a type polisher she had suffered much from ill health. Three months after taking to this employment she became tainted with lead poisoning, and suffered from printers' colic. Four years later she had a second attack of colic and suffered intense pain; shortly after she became pregnant and was delivered of a dead child. Three years elapsed and she had a miscarriage at the fifth month of her pregnancy. Besides these two cases of pregnancy she had become eight other times pregnant, and each time, after a short suppression of the menses, and the delay of two or three months, she miscarried, characterized by an abundant menorrhagia, and accompanied with colicky pains at the time.' • M. Paul goes so far as to assert that if the father be tainted, the offspring may be affected in utero, even though the mother has nothing to do with lead."-Baker. 16 242 A TEXT-BOOK OF GYNECOLOGY. tion, etc.-may likewise transmit an unnatural stimulus to the uterus. Some of the reflex causes have already been referred to, notably, ovarian and mammary irritation. Vesical and rectal irritation, especially if tenesmus is marked, may act in the same. way. Congestion of the rectum and the uterus are not infre- quently associated: the latter resulting in menorrhagia and the former in hemorrhoids. The effect of impressions conveyed through any of the reflex channels probably would not be sufficient to excite uterine hemorrhage were the uterus perfectly normal; however, with the organ already the seat of disease which has increased its vascularity, hemorrhage is easily excited and maintained by irritation remote from the pelvis. Malignant Lesions.-Under this head I have enumerated carcinoma and sarcoma. In the later stages there is but little difficulty in diagnosing their presence, but at the time of their onset there may be the greatest difficulty in so doing. It is important to remember that hemorrhage is by no means an early symptom in all cases of malignancy, nor, indeed, in the majority. According to the statistics of Dr. West it is the first symptom only in about 44 per cent. of uterine cancers. When an early symptom it is the result of congestion of the endo- metrium; later on it is due to ulceration, which, by invading the vascular structures, gives rise to a profuse and occasionally fatal hemorrhage. The amount of blood lost depends in no small measure upon the location of the disease; it is much more profuse when the fundus is involved, and may or may not be accompanied with pain. When an unnatural loss of blood is the only symptom of malignancy which presents itself the uncertainties are very great, and the microscope may be the only means of making a positive diagnosis. If the hemorrhage occurs at or near the so called cancerous age, i. e., from forty to fifty, and if it recurs during the intermenstrual period as well, the possibilities of cancer are very great, and a careful investigation should be made. In the later stages there usually exists with the hemor- rhage an offensive leucorrhea, which, together with the cachexia, make the presence of malignancy almost certain. MENSTRUATION AND ITS DISORDERS. 243 The symptoms of sarcoma do not differ materially from those of true carcinoma, except that in its formative period there is often a free "rice-watery" discharge, containing grayish-white shreds, which does not become offensive until after necrosis of tissue sets in. Other than this there is little in the subjective history which will enable the examiner to differentiate these two forms of malignant disease. When cancer takes on the form of cauliflower excrescence the hemorrhage may be induced by sexual congress, walking, coughing, straining at stool, etc. Non-malignant Lesions.-Hemorrhage resulting from the several varieties of fibroid tumors varies greatly-the amount depending in large measure upon the nature of the growth. It is much more profuse in sub-mucous growths than in interstitial or sub-peritoneal. The hemorrhage does not come from the tumor itself but from the congested and hypertrophied mucous membrane covering it. The unnatural flow is at first purely menorrhagic, the discharge increasing from month to month until finally it becomes almost persistent, and at times danger- ously profuse. As the tumor increases in size pressure symp- toms develop, and the patient usually detects its presence before consulting her physician. The amount of hemorrhage produced by the various types of polypi is by no means governed by the size of these growths. Sometimes a very small polypus will excite a most alarming and even fatal hemorrhage; however, the presence of very large ones may give rise to no inconvenience until after being forced into the vagina. Mucous tumors are very much more liable to excite hemorrhage than are fibrous, and, when small, they are often detected with difficulty. One not larger than a hazelnut will remain concealed within the uterine cavity until the cervix is forcibly dilated. The hemorrhage proceeds in mucous. polypi from the surface of the tumor as well as from the endo- metrium. Menorrhagia or metrorrhagia is a most common symptom in endometritis and subinvolution. Congestion and congestive hypertrophy cause an increase in the vascularity of the endo- metrium and, not infrequently, it undergoes a “fungoid degen- eration." These fungosities play an important part in the 244 A TEXT-BOOK OF GYNECOLOGY. etiology of menorrhagia, and when the flow is at all intractable they should be looked for. Subinvolution is a frequent sequel of cervical lacerations. Inflammatory deposits within the pelvis, with or without the presence of pus, are often responsible for menorrhagia of a most obstinate type which cannot be reached by the ordinary reme- dies. Uterine congestion and endometritis are usually secondary to pelvic inflammation. Involvement of the tubes and ovaries is a most prolific cause of menorrhagia. Accidental.-Uterine inversion is an accident which ought, under all circumstances, to be recognized at the time of its occur- rence. Strangely enough it sometimes remains undetected until persistent hemorrhage leads to an exploration. In menor- rhagia due to this cause the hemorrhage usually dates from delivery, is severe at first but gradually becomes less; it recurs at intervals corresponding to the menstrual cycle; it is attended by a profuse and almost constant leucorrhea; and there will be found on local examination a tumor which remains within the vagina, or presents externally. There may be much difficulty in differentiating an inverted fundus from a protruding polypus.* It is hardly proper to designate hematocele as one of the causes of uterine hemorrhage. Indeed, the cause of both the hematocele and the excessive hemorrhage is usually one and the same-a ruptured extra-uterine pregnancy cyst, some form of general systemic depravity or some abnormality of the uterus, peritoneum, ovaries, or tubes. In connection with the subject of menorrhagia and metrorrhagia it is, however, important to remember that a pelvic hematocele, either intra- or extra- peritoneal, may be accompanied by an exaggerated flow of blood externally. The constitutional symptom's resulting from the hematocele are those of shock and collapse and will be indicated by the countenance, pulse, respiration, etc. The ordinary forms of uterine displacement give rise to menor- rhagia by inducing a congestion of the uterus and its append- ages. Hewett particularly emphasizes the importance of flex- ions as causative factors; and while he may exaggerate their * v. p. 109. MENSTRUATION AND ITS DISORDERS. 245 importance the fact remains that in many instances menorrhagia cannot be cured until the displacement is put right. Pregnancy. In uterine hemorrhage proceeding from an abor- tion the history of previous suppression will usually suggest the cause; it must, however, be remembered that menstrual sup- pression does not always follow upon conception. The hemor- rhage accompanying abortion comes on gradually and the pains recur at regular intervals; they are accompanied with shivering and, frequently, nausea and vomiting; the flow of blood usually ceases upon the expulsion of the ovum, and, if the uterus has been thoroughly emptied, does not recur. If, on the contrary, any of the membranes are left behind, the flow will continue until the curette has been applied. The retained products of conception may be carried for an indefinite length of time before the real cause of the unnatural discharge is discovered. This is oftener the case in early miscarriages, the existence of preg- nancy not being suspected. When placenta previa is responsible for the hemorrhage, the circumstances are less confusing, for the placental separation rarely takes place until the later stages of pregnancy, when the patient knows that she is pregnant. A digital examination will reveal the unnatural implantation of the placenta; in acci- dental hemorrhage, i. e., hemorrhage resulting from the separa- tion of a normally located placenta, a vaginal examination will at least show that the placenta is not attached to the cervix. Climacteric.—Women who have been in the habit of men- struating profusely, and especially if full-blooded, frequently lose more blood as the change of life approaches. The age of the patient, together with her family history, will serve as a guide in determining whether or not the increased loss is the result of climacteric changes. I question, however, the entity of a physiological climacteric hemorrhage, if such an expression is permissible. The prevailing idea that hemorrhages at this age are natural has resulted in much harm. Conclusions. For guiding aphorisms in dealing with uterine hemorrhage the reader is referred to page 76. The practice of relying absolutely upon subjective symptoms and the indi- cated remedy, when the loss of blood is at all persistent, is not 246 A TEXT-BOOK OF GYNECOLOGY. only reprehensible but should be actionable as well. I fully appreciate the value of internal medication in dealing with menorrhagia and metrorrhagia, but, in at least a goodly propor- tion of cases, something more is demanded. A careful examin- ation, both local and general, must be instituted, the cause sought for, and, if possible, removed. The physician should bear in mind that he is dealing with a symptom of something wrong elsewhere, and not a pathological entity. If the hemor- rhage is an expression of malignancy the lesion may advance beyond the operative stage before it is discovered; if, on the other hand, it be due to causes other than malignancy the pro- longed drain upon the system may result in anemia, general anasarca, hysteria, neurasthenia, depraved nutrition with pro- found emaciation, and death. The prognosis of uterine hemorrhage will depend entirely upon its cause. In dealing with anemia associated with menor- rhagia it must not be forgotten that, unlike amenorrhea, uterine hemorrhage is more often the cause than the result of the blood depravity. When the causes are purely local gynecological surgery has reached a degree of perfection which makes it pos- sible to accomplish a cure, except in advanced malignancy, in nearly every instance. TREATMENT. The treatment of uterine hemorrhage may be conveniently ´studied under the following heads: (a) General; (b) Conduct of patient during the period; (c) Treatment of local causes; (d) Immediate control of hemorrhage; and (e) Therapeutics. The general treatment should include the various measures recommended for amenorrhea. A prescribed diet is often of the greatest utility: if the patient is plethoric and of sedentary habits it should be restricted; if, on the other hand, her nutri- tion is below par it should be generous. Out-door exercise is to be recommended in all instances where counter indications do not prevail; or if the hemorrhage is brought on by it, and particularly if prostration is a marked symptom, all forms of exercise may have to be proscribed. Fresh air and sunlight are, however, curative agents that can in most instances be utilized, even though the patient cannot go out-doors. All clothing MENSTRUATION AND ITS DISORDERS. 247 + should be suspended from the shoulders so as to avoid con- stricting the waist, and crowding the abdominal organs into the pelvis. Constipation is an important factor in keeping up pelvic congestion and should be corrected; inactivity of the liver like- wise obstructs the pelvic circulation, hence measures tending to overcome hepatic sluggishness are to be instituted. If one or more of the several constitutional causes exist, the treatment most appropriate for such causes must be adopted. If the patient reside in a malarious region a change of climate may be necessary before a cure can be accomplished. In short, what- ever be the cause of the unnatural discharge, our treatment must be directed toward it. During the period, and for a day or two previously to its onset, the patient should exercise as little as possible. The recumbent posture, and, if the hemorrhage is alarming, the recumbent posture with the foot of the bed elevated, should be maintained. Of first importance for the immediate control of the hemorrhage is heat. The hot douche, ranging in temperature from 110° to 120°, is a therapeutic resource in uterine hemorrhage whose value cannot be overestimated. When used for its immediate effect, however, its thermic properties are indispensable. This implies a temperature of not less than 110°, and the maximum 120° is still more useful. The proper method of administering the douche is described in another place.* The primary action of cold is to contract blood-vessels-hence its usefulness in controlling hemorrhage. Unfortunately its secondary action is that of dilatation, so that in most instances heat is by far the better agent. Another advantage which heat possesses over cold as a hemostatic, is that it does not shock. the system as does the latter. Nevertheless, cold will some- times succeed in promoting uterine contractions when heat fails, and is, therefore, to be held in reserve. Indeed, the alternate use of heat and cold will sometimes cause the uterus to contract when either agent used alone is ineffectual. It may be applied in the form of a vaginal douche, or by the aid of an ice-bag within the vagina or over the pubis; or by cloths wrung from * Chapter X. 248 A TEXT-BOOK OF GYNECOLOGY. cold water and applied to the lower abdomen. An ice-bag placed over the lower spine is sometimes most effectual. When the evidences of shock and collapse are at all prominent cold must be used with the utmost caution; if these symptoms obtain, and the hot douche has failed to control the hemorrhage, other measures about to be described are preferable. Failing to control the loss of blood by the use of heat and cold the tampon is indicated in all forms of uterine hemorrhage, except post-partum hemorrhage after the fourth month. In placenta previa and accidental hemorrhage it is indicated provided the uterus has not expelled the fetus. The hemorrhage may occur at any time during utero-gestation; after the fourth month, however, if the fetus has been expelled, the uterus will hold sufficient blood to make the use of the tampon dangerous. Antiseptic cotton prepared and introduced according to the directions given in Chapter X, is the best material for the con- struction of tampons. In cases of emergency any material— roller-bandage, silk handkerchief, tarred jute, etc.—may be used, provided it is clean. Tamponnement of the vagina, to prove effectual in controlling hemorrhage, must be thoroughly done, so that there can be no leakage about or through the tampons. One or two wads of cotton, loosely placed against the cervix, are not only absolutely useless, but do more harm than good, for their presence tends to excite hemorrhage. They should not be retained longer than eight or ten hours when used for this purpose, and their introduction should be preceded and followed by an antiseptic douche. The cervical plug—tents or the Barnes bag is hardly to be commended except in placenta previa or when dilatation of the cervical canal is imperative. There is a tendency to abandon the use of tents for dilating purposes, be- cause of the danger of sepsis attending their use. If dilatation is indicated the rapid method under ether is the preferable one. Astringents are rarely necessary to supplement the action of the tampon. Occasionally, however, passive hemorrhage will con- tinue from the uterine cavity in spite of the foregoing methods. The blood-vessels and capillaries may remain unaffected not- withstanding the application of heat and cold, and the uterus may not respond to ordinary stimuli: in rare instances of this MENSTRUATION AND ITS DISORDERS. 249 kind astringents are useful. They must be applied directly to the bleeding surface. Alum, tannin, hamamelis and iron, are those most frequently used. Alum, in the form of a saturated solution, may be cautiously injected into the uterine cavity pro- viding the os is patulous. Any intra-uterine injection must be administered with the utmost care: no force should be used in its introduction and unless the cervical canal is sufficiently open, a reflux catheter is necessary. In short, provision should always be made for the ready exit of the fluid when thrown into the uterine cavity. The fluid used should always be warm. If the hemorrhage proceeds from the cervix or vagina the alum solution can be advantageously used in a vaginal douche. It is an excellent agent in controlling hemorrhage after cervical FIG. 58. G.TIEMANN & CO- O BOZEMAN'S REFLUX UTERINE CATHeter. and plastic operations within the vagina, for it does not form coagula to interfere with union as does iron and as other more powerful astringents do. Hamamelis (1: 20) may be used instead of the alum, and in the same manner, if the hemorrhage is of a decidedly venous character or the remedy is called for because of constitutional symptoms. Tannin and iron, to prove useful, must be concentrated, and are best applied directly to the endometrium by means of an applicator. Tannin is highly recommended by many authors, but I believe that its action is more uncertain than that of iron, and in all instances where the former is useful the latter will prove more so.. The patient should be placed in the Sims pos- ture, the cervix fixed, the coagula washed away with a bichlo- rid solution (1:5000) and the chlorid of iron, diluted with 250 A TEXT-BOOK OF GYNECOLOGY. twice its bulk of water, applied over the entire endometrium. This heroic method should never be resorted to except when all ordinary measures have failed, for coagula left within the uterine cavity are always dangerous. Its use is only justified when the patient's life is threatened by an otherwise uncontrollable hem- orrhage; we then use it to avoid a great and pressing danger by running the chance of a lesser one. Treatment of Local Causes.-The treatment of the several local causes, both malignant and non-malignant, is given in detail in other chapters. A few general considerations are, however, necessary at this time. Fibroid tumors may, and frequently do, necessitate operative interference; uterine displacements are to be corrected by appropriate measures; endometritis and subin- volution should be attacked by proper local and internal treat- ment-the local measures comprehending the intelligent use of the curette and the reparation of cervical lacerations; finally, the products of abortion, if they exist, should be sought for and removed. In dealing with these various conditions the curette is so frequently called for as to warrant a careful description of the technique of its application. The Application of the Curette.-The use of this instrument for diagnostic purposes has already been referred to (v. Chapter V). In its application for either diagnostic or curative purposes certain precautions are necessary: it should never be used if acute inflammation, either of the uterus or of the tissues about the uterus, is present; it is to be resorted to with the utmost caution if long-standing inflammatory deposits within the pelvis exist; last, but not least, the greatest cleanliness should be observed in its application. Since adopting the antiseptic precau- tions of Leopold, whose method I learned from personal obser- vation, I have never had to contend with a single unpleasant symptom following its application. The patient, anesthetized, is placed either in the semi-prone or the lithotomy posture and the perineum retracted with a Sims speculum, through which the vagina and cervix are thoroughly cleansed with a 1 : 3000 bichlo- rid solution.* After fixing the cervix with a tenaculum or vol- * When the Frisch specula are used, the patient is placed in the lithotomy posture. MENSTRUATION AND ITS DISORDERS. 251 sella, the mucus is carefully wiped from the cervical canal with antiseptic cotton held in dressing forceps. Impure or commer- cial carbolic acid is next applied to the entire endometrium, both cervical and corporeal, after which the curette, previously dipped in carbolic acid, is passed into the uterine cavity. It is then applied in such a way as to reach all parts of the uterine cavity, thus removing fungoid masses, or the products of con- ception, which can be saved for microscopic examination. An especial effort should be made to reach the cornua uteri, for it is in these localities that the products of inflammation are more frequently found, and in two uteri removed per vaginam, I have found small polypoidal masses imbedded deep into the tissues of one horn. For a long time I used only Thomas's dull wire FIG. 59. GTIEMANN & CO EMMET'S CURETTE FORCEPS. curette (Fig. 46) looking upon the sharper instrument as both dangerous and unnecessary. This prejudice was inherited from Emmet, who has gone so far as to condemn in toto the use of the curette, substituting for it his curette forceps (Fig. 59), whose cutting edge enables the operator to remove the fungoid masses by separating and approximating its blades. By observing the counter-indications cited, together with the strictest antiseptic precautions, I am convinced, both from personal experience and the experience of men who have resorted to it many hundreds of times, that the use of the sharp instrument, while it is attended with no more danger than that of the dull, is infinitely more effectual. I prefer Simon's sharp spoon curette to the Sims (Fig. 45). After the curetting the débris and blood should be removed with absorbent cotton and the compound tincture of iodin 252 A TEXT-BOOK OF GYNECOLOGY. (Churchill's), or carbolic acid, applied to the entire endome- trium. The vagina is next packed with tampons saturated with glycerin and liberally sprinkled with iodoform. This is done for two reasons: first, a smart hemorrhage may follow the curet- ting unless this precaution be taken; and second, any excess of iodin or carbolic acid coming in contact with the vaginal walls is at once neutralized by the glycerin. The patient is placed in bed, where she should remain for four or five days; if there is much pain the hot douche and the indicated remedy are to be resorted to. curette. In the' foregoing description it is presupposed that the cervical canal is sufficiently patulous to admit of the introduction of the Indeed in most instances where curetting is indicated the pathological conditions calling for it give rise to such patu- lousness. Should, however, the canal be found too small to admit the instrument it can be dilated by the introduction of graduated sounds or by divulsion. In general terms, then, the curette is indicated in uterine hem- orrhage after less radical measures have been exhausted when any of the primary pathological lesions enumerated have given rise to secondary endometritis and uterine fungosities. Fibroid tumors, polypi, subinvolution, uterine displacements, chronic pelvic congestion,-any or all of these lesions frequently result in changes in the endometrium necessitating its use. In malig- nant lesions also it may be advantageously used as a prepara- tory measure previously to total extirpation, or as a purely palliative one in incurable carcinoma. When the hemorrhage is due to subinvolution or hyperplasia the use of electricity may accomplish much good. Therapeutics. China.-HEMORRHAGE FROM ATONY OF THE UTERUS; espe- cially useful in those who have lost much blood, with ringing in the ears, faintness, coldness, loss of sight, etc.; menses too early, profuse and CONTAIN BLACK CLOTS; great distention of the abdo- men. Cases of malarial origin, when the symptoms show a marked periodicity, and also for women suffering from sexual excesses."-Southwick. (( MENSTRUATION AND ITS DISORDERS. 253 Ipecacuanha.-NAUSEA AND VOMITING; discharge of bright red blood occurs with a gush at every effort to vomit; heat about the head and debility; GASPING FOR BREATH; menses too early and profuse. "If the hemorrhage is very severe and it seems desirable to stop it at once, I give ipecacuanha, unless some other remedy is characteristically indicated."-Winter burn. Belladonna.-THE FLOW IS BRIGHT RED AND IMPARTS A SENSE OF HEAT; bearing down, as if the organs would protrude from the vulva; congestion of the head with throbbing of the carotids. Calcaria Carb.-Menses too frequent, too profuse and last too long; profuse menstruation during lactation; LEUCOPHLEG- MATIC CONSTITUTION. * Hamamelis.-PASSIVE HEMORRHAGE WITH ANEMIA; ABSENCE OF UTERINE pains with a discharge of dark-colored blood; hem- orrhagic diathesis with varicoses; ovarian irritation and inflam- mation; leucorrhoea with great tenderness. Sabina.-Menses too profuse, too early, partly fluid, partly clotted and offensive; pains from sacrum to pubes; metrorrhagia increased by least motion, but often worse from walking. Platina. Metrorrhagia with dark, thick blood; pain in the small of back, which extends into both groins; EXCESSIVE SENSI- TIVENESS of the genital organs; great sexual excitement in preg- nant females; sensitiveness of the ovaries with burning pain; menses accompanied by spasm or by painful bearing down in uterine region. Crocus Sat.-Menorrhagia of dark, stringy blood; sensation as if something alive were rolling or turning about in the abdomen; metrorrhagia after abortion worse from the slightest motion ; subinvolution. Nitric Acid. Menses too early and too profuse, with urine emitting an intolerably strong smell; the blood is very dark colored and thick.-Guernsey. Trillium.—Active uterine hemorrhage of dark, thick and *"When the menses are too frequent and profuse, and especially if the patient is of a strumous habit, with a tendency to pectoral disorder, calcaria carb. is, par excellence, the appropriate remedy."-Ludlam. 254 A TEXT-BOOK OF GYNECOLOGY. clotted blood, especially during climaxis; hemorrhagic diathesis, pain in hips, short breath, palpitation, restlessness in legs.* Secale Cornutum.-Passive hemorrhage with very fetid blood in FEEBLE, CACHECTIC PERSONS, particularly when the weakness was not caused by previous loss of blood (Jahr); frequent labor- like pains with chronic metritis. Erigeron. A profuse flow of bright red blood, aggravated by the least motion; pallor and weakness in consequence of the discharge. Ferrum.—Menorrhagia in weakly persons with a fiery red face; tenesmus of the bladder and diurnal enuresis ; sharp pains in abdomen, bearing down in uterus, painfulness of the vagina. Plumbum.—Menorrhagia with sensation of a string pulling from abdomen to back; climacteric period; dark clots alternating with fluid blood or bloody serum; Bright's disease, constipa- tion with feces composed of hard balls. Consult :-Agaricus, arnica, bovista, cactus grand, cantharis, collinsonia, lachesis, phosphoric acid, pulsatilla, sepia, sulphur, cannabis ind., hydrastis, lilium tig. "" Illustrative Cases. CASE XXIII.-Hydrastis Canadensis in Uterine Hemorrhage.-S. S., 51 years of age, married, has four children, consulted me on April 15th, 1887, for "bleeding from the womb, which has continued off and on since Christmas, 1886." Has always been regular every month, the flow being profuse and lasting generally a week. Un- til Christmas, 1886, had never suffered from metrorrhagia. On examination a hard, irregular fibroid tumor was found occupying the anterior and left lateral wall of the uterus. The sound passed for a distance of 3½ inches into the uterine cavity. The new growth rose one inch above the fundus uteri on the left side. The patient was ordered Pot. Brom. gr. x, and Ext. Ergot., Liq., mxxx, in a mixture three times a day. On April 29th, a fortnight after her first visit, the "hemorrhage was still ex- cessive." On May 20th, as the flooding still continued, a mixture of Pot. Brom. gr. x and tinct. Hydrastis mxx was ordered, with the result that the hemorrhage ceased.— Henry T. Rutherford, B. A., M. B. The British Gynecological Journal. Volume IV. CASE XXIV. Cannabis Indica in Menorrhagia.—Mrs. B., æt. 34, mother of three children, youngest five years old, has not been pregnant since this child was born. *"One of the best remedies I know of in ordinary profuse menstrual flow, coming frequently and yet without any decided constitutional character by which to judge the case, is Trillium pendulum, especially if the flow exhausts the patient very much. I have never given it in any potency except the sixth. That has been sufficient in all my cases."-Farrington. MENSTRUATION AND ITS DISORDERS. 255 Has for the last three or four years been troubled with profuse and frequently recurring menstruation. Present condition: Some eighteen days since her menses made their appearance, since which time they have been very profuse and painful, the discharge being very dark but without clots. Is very anemic, suffers great mental agitation, anxiety, irri- tability, nervousness, loss of sleep (not having been able to sleep for two nights), pale face, cold hands and feet, violent uterine colic, so severe as to induce cramps in the extremities. For this condition she had had such remedies as arsenicum, china, cyclamen, etc., and is apparently getting worse. As a dernier resort I prescribed Cannabis Indica 1st. dec. dil. gtt. x in a tumbler half full of water, a teaspoonful to be given every hour. On my next visit I learned that after taking the third dose she became calmer, her pains grew less and she fell into a gentle slumber. On waking the nervousness was gone, the violent colic much better and all of her symptoms very greatly modified. I continued the remedy at long intervals for three days, when she expressed herself as being perfectly well. She has menstruated at regular periods three times since, and each time with less difficulty until the last time, which she says lasted only four days and was quite natural for the first time in three years. She has in the meantime taken no other medicine except Cannabis Indica.-Richardson. CASE XXV.-Mrs. H., æt. 30, has been confined to her bed for six days with a violent menorrhagia, accompanied by a terrible uterine colic of a spasmodic nature, the pains returning like labor pains; she has also great nervous agitation accom- panied with sleeplessness. The can. ind. was given in three-drop doses of the Ist. dec. dilution, every half hour; in a few hours she was very greatly relieved, and by a continuance of the medicine she was in two days discharged cured. I have given it in several other cases in which I neglected to note the details, but the results being of such a nature as to prove it to be of great utility in those pros- trating cases of menorrhagia in which the mental agitation and violent uterine colic seem to be the predominating symptoms; in such cases I can at least advise the profession to give it a trial.— Wm. C. Richardson, M. D., American Observer, 1871. CASES ILLUSTRATING THE USE OF THE CURETTE IN UTERINE HEMORRHAGE. CASE XXVI.—Mrs., æt. 38, married and the mother of three children. This patient is exceedingly delicate and does not weigh more than ninety pounds. Has always menstruated profusely, but since the birth of her last child, now eight years old, the quantity of blood lost grew more and more excessive until she became almost ex- sanguinated; the mucous membranes being blanched, the skin pale, and the anemic murmur quite distinct. What little strength she could gain during the intermenstrual period was entirely lost at the next appearance of the flow. Cannabis Indica, together with the hot douche, controlled the hemorrhage in a measure, but the relief was not lasting, the patient growing steadily worse. On July 21st, 1891, ether was administered and the sharp curette applied. Large quantities of fungoid débris were removed, which so much resembled that of diffuse sarcoma as to make me exceedingly anxious until the microscope revealed its true nature. The compound tincture of iodin was next applied to the entire endometrium, and a supporting tampon placed against the cervix, which was removed as soon as the vomiting ceased. The patient was kept in bed for two weeks and an antiseptic 256 A TEXT-BOOK OF GYNECOLOGY. douche used twice daily. The first period was characterized by no perceptible diminution of the discharge, nor was the improvement marked in the two following periods. However, the loss of blood gradually diminished, so that in six months after the curetting, instead of flowing excessively, the menses were scant. She rapidly gained in strength and is now quite well. CASE XXVII.-M., æt. 48, and unmarried. An interstitial fibroid large enough to fill the lower pelvis was the cause of a uterine hemorrhage which at first was menor- rhagic in character but soon became metrorrhagic; the flow, although worse at certain times of the month, became almost continuous. I dilated the cervix under ether and applied the sharp curette in the usual manner. The hemorrhage began to diminish at once and did not become again excessive until one year from the time of the first curetting. The operation was then repeated with equally good results. The patient is still under observation. These two cases show the usefulness of the curette when indicated, and it is unnec- essary to multiply them. I have used the instrument many times and have rarely been disappointed in the results obtained. Even where malignancy is suspected, and the chief object of applying the curette is to obtain tissue for the microscope, it is my practice to apply it most thoroughly, because the progress of a diffuse sarcoma or carcinoma is often stayed by such a procedure. When the operation precedes trachelorrhaphy it in most instances enhances the favorable results of the latter operation, particularly if the lacerated cervix is associated with subinvolution and menorrhagia. CHAPTER XVIII. MENSTRUATION AND ITS DISORDERS (Continued). DYSMENORRHEA. FORM. ETIOLOGY. SYMPTOMS. DIAGNOSIS. PROGNOSIS. Neuralgic. Gout and rheuma- Variable; pain sharp tism; chlorosis; malaria; anemia; sexual irregulari- ties. and fixed or reflex; time of pain vari- able-before, dur- ing or after thel flow; aggravated by cold drinks or exposure. Pains not expulsive; Depends upon flow uninterrupted; absence of clots and physical causes. cause and hab- its of patient; usually favor- able. Anything that will Pain for some days Pain precedes flow; Must be guard- Ovarian, the ovaries. congest or inflame Congestive and Congestion or inflam- inflammatory. Obstructive. mation of any of the pelvic viscera ; undue exposure; mental shock; dis- placements; tum- ors. Cervical stenosis and spasm; flexions; polypi; tumors; vaginal occlusions. + Membranous. Various theories; usually associated with endometritis. before flow or dur- ing intermenstrual period. Charac- ter.-Dull and ach- ing, or sharp and stinging, frequently extending down thigh; pain in the breast. enlargement, ten- ed. derness, and fre- quently displace- ment of one or both ovaries. Sudden attack of Suddenness of onset; Depends upon pain during men- struation with sup- pression; constitu- tional disturb- ances; vesical and rectal tenes- mus. Menstrual symptoms minus the flow; or intermittent spas- modic pain relieved by a gush of blood. Pain and flow simul- taneous; labor-like pains ceasing upon the expulsion of clots or mem- branes: purulent leucorrhea. suppression with cause; usually favorable. constitutional dis- turbances; evi- dences of local disease. Expulsive pains fol- Usually favor- lowed by free dis- able. charge of blood and clots with relief; flow intermittent; presence of ob- struction. ed. Periodical discharge Must be guard- of membrane. From abortion.— History and repe- tition. From blood casts and casts from the vagina.- Microscopical ex- amination. General Considerations.-The term dysmenorrhea is purely a relative one and is used to designate painful menstruation, whether due to functional or to organic disease of the female generative system. Like amenorrhea and menorrhagia it is a 17 257 258 A TEXT-BOOK OF GYNECOLOGY. symptom of various disorders; and the division into forms only serves to indicate, in a general way, some of the affections with which painful menstruation is associated. The forms usually given are: 1, Neuralgic; 2, ovarian; 3, congestive or inflamma- tory; 4, obstructive; and 5, membranous. This division also serves to explain the great difference of opinion which exists among various authors regarding the cause of the pain in dysmenorrhea. Thus some writers, notably Wylie and Goodell, affirm that in all instances the pain is due to the retention of the menstrual fluid, and the consequent distention of the uterus. Emmet believes that anemia, inducing a tendency to neuralgia, is the most prolific cause of dysmenorrhea; accord- ing to this writer dysmenorrhea is oftener due to constitutional than to local affections. Other writers attribute the pain in nearly all instances to inflammation and disease of the uterine append- ages. The probable truth is that no single explanation will apply to any two cases of dysmenorrhea; and that the several causes suggested by the older classification of Simpson and Thomas, are more clearly in harmony with clinical facts than is a path- ology based upon a single theory. One or more of the causes enumerated might exist for an in- definite length of time without giving rise to dysmenorrhea, were it not that certain local changes induced by them render the nerves supplying the uterus, the ovaries, or the surrounding structures, morbidly sensitive. If the uterus or its annexa become hyper- esthetic, a degree of distention which would give rise to no suf fering in a perfectly normal organ may excite the most excru- ciating pain in one thus affected; or the ordinary congestion of menstruation may be sufficient to cause pain when local inflam- mation has already induced this morbid state of the terminal nerves; or anemia, chlorosis, rheumatism, malaria, etc., may give rise to local distress, because the expression of pain inci- dent to these various diathetic troubles oftener occurs in parts of the body already weakened by local changes. The clinician will rarely meet with any one form of dysmen- orrhea uncomplicated, though the clinical manifestations of one form frequently stands out with sufficient prominence to over- shadow all others. Usually two or more varieties blend with MENSTRUATION AND ITS DISORDERS. 259 one another so intimately as to make differentiation impossible. Nevertheless, for the convenience of study, the classification is useful. Neuralgic Dysmenorrhea.-The etiology of this form of pain- ful menstruation can be summed up in the term "neuralgic diathe- sis;" a term which means so much and yet so little. Were a defini- tion of it required, based upon accurate pathological deductions, it would not be forthcoming. Nevertheless, there sometimes exists, particularly in women, a peculiar state of the system which renders the victim liable to sudden attacks of pain in various organs of the body. Frequently there is a rheumatic or gouty basis to the diffi- culty; or the general health may have become depreciated by anemia, chlorosis or malaria. The victims of neuralgic dys- menorrhea are oftener found among that class of women who lead a sedentary and luxurious life, and, not infrequently, sexual irregularities complicate matters. Painful menstruation is not the only expression of the peculiar constitutional bias: gas- tralgia, cardialgia, migraine, and other neuralgic manifestations, are liable to occur from time to time, particularly if the patient has been subjected to excesses or undue exposure of any kind. The symptoms are as changeable as are the symptoms of neuralgia generally. It is this peculiarity, however, which enables the practitioner to detect the nature of the case in hand. The pain may be sharp and fixed in some portion of the pelvis ; or it may be shifting and reflected to any part of the body. Dr. Thomas records two cases, in one of which, during each period, the patient suffered intensely from pain limited to the outer side of the little finger; the second experienced for several days before the flow a violent pain at the root of the nose. The occurrence of the pain relative to the flow is variable; it may set in before, during or after the flow. It is often precipi- tated by the slightest indiscretion, so that the patient cannot in- dulge in a cold drink or an ice without suffering the penalty. It will often vanish as suddenly as it appeared and the victim will quickly pass from a state of acute suffering to one of compara- tive comfort. The diagnosis of this form of dysmenorrhea is to be made by exclusion. The pains are non-expulsive, there is an absence 260 A TEXT-BOOK OF GYNECOLOGY. of clots in the discharge, and a local examination will fail to reveal the causes which give rise to the other forms about to be considered. These facts, together with the diathetic history, will afford sufficient data upon which to base a diagnosis. The prognosis will depend upon the possibility of correcting the constitutional trouble responsible for the mischief. With the coöperation of the patient a cure can in most instances be accom- plished. Ovarian Dysmenorrhea.—Many authorities deny in toto that ovarian lesions ever give rise to painful menstruation. Indeed it is even contended by some that menstruation, instead of aggravating existing ovarian lesions, relieves them by reliev- ing pelvic congestion—a statement in proof of which there exists certain clinical evidence. Nevertheless this does not prove that ovarian irritation and inflammation may not play an important part in the causation of dysmenorrhea; for, unless we maintain that the ovaries play no part in menstruation (a theory, as we have seen, which is hardly susceptible of proof), it is but reasonable to presume that there may be transmitted to the uterus a morbid as well as a normal ovarian stimulus. Ovarian pain may be relieved by menstruation, because of the depleting effect incident to the mere loss of blood; but before such relief comes, an increase of suffering is caused by the dehiscence of a Graafian follicle in an ovary the seat of pathological changes. The etiology is that of ovarian irritation and inflammation. Anything that will congest or inflame these organs may be the indirect cause of ovarian dysmenorrhea. Cauterization of the cervix, a practice which, fortunately, has justly fallen into disre- pute, is especially emphasized by many writers as a causative factor. Sexual excesses or irregularities are likewise prolific causes. Frequently ovarian displacement, with or without uterine, is associated with the dysmenorrheal trouble. Symptoms. The pain of ovarian dysmenorrhea occurs and persists for some days preceding the onset of the flow, and is usually limited to one or both ovarian regions, oftener the left. Not infrequently it extends down the corresponding thigh, and reflex pain in the mammary region is often induced. In char- acter the local pain is dull and aching, or stinging and burning. MENSTRUATION AND ITS DISORDERS. 261 Dr. Priestly long ago called attention to what he termed an "intermediate pain," occurring on a given day during each inter- menstrual period. Whether or not this pain is due to intermen- strual ovulation without menstruation cannot be determined. The fact remains that in a certain number of cases of ovarian dysmenorrhea this pain will recur almost to a certainty on a given day. In one of my cases it occurred on the fourteenth day after menstruation; in another on the twelfth-in each instance persisting for several days. Ovarian dysmenorrhea is to be differentiated from the other forms: by the onset of the peculiar pain some days before the appearance of the flow; by the tenderness and, frequently, dis- placement of one or both ovaries; by the uninterrupted flow; and by the absence of serious constitutional disturbance. The prognosis must, under all circumstances, be guarded. So long as menstruation continues the ovaries are subjected to a periodical congestion which makes it exceedingly difficult to cure an existing irritation or inflammation. The nearest approach to "physiological rest" which can be given them is pregnancy and lactation. Unfortunately ovarian dysmenorrhea occurs quite as often in the unmarried as in the married; and when it does present itself in the married the victims are frequently sterile. Nevertheless the prognosis, under treatment which brings to the patient a class of remedies not utilized by the older school, is by no means as sinister as the writers of that school lead us to believe. If irreparable damage has been done to the appendages oöphorectomy remains as a last resource. 4 Congestive and Inflammatory Dysmenorrhea.—This form of painful menstruation is accompanied with, and characterized by, the symptoms of congestion and inflammation. It is indeed a symptom of most of the inflammatory diseases of the pelvis, and it is brought on by the same causes which give rise to congestion or inflammation of any of the pelvic viscera. On the other hand it may mark the beginning of inflammation. Undue exposure to wet and cold during menstruation, is one of the most frequent exciting causes. The symptoms depend largely upon the degree of constitu- tional disturbance excited by the local changes. When occur- 262 A TEXT-BOOK OF GYNECOLOGY. ring as a primary condition there is usually a sudden attack of pain during menstruation, with a partial or complete cessation of the flow. If the congestion stops short of inflammation, the constitutional disturbance will be limited to a slightly increased intra-arterial pressure, with headache and nervous phenomena; if, on the contrary, actual inflammation already exists, or if the congestion incident to the menstrual suppression leads to actual inflammation, the local suffering is that of pelvic peri- tonitis. The pulse and temperature are increased, and there may be marked delirium. Occasionally vesical and rectal tenesmus become distressing. The distinguishing features of this form of dysmenorrhea are: I, the sudden onset of pain with the more or less complete suppression of the flow; 2, the constitutional impression, which is sometimes profound; and 3, the evidences of local tenderness or lesions obtained by physical exploration. Prognosis.-The prognosis will necessarily depend upon the cause or causes giving rise to the dysmenorrhea. If the local changes are limited to simple hyperemia, the equilibrium is easily restored by proper treatment and the succeeding menstrual period is not characterized by marked suffering. However, if the products of inflammation are left behind, or if the dysmen- orrhea is due to preëxisting cellulitis or peritonitis, the pros- pects of relief will depend upon the curability of the pelvic lesion. Obstructive Dysmenorrhea.—The causes giving rise to ob- structive dysmenorrhea are stenosis of the cervical canal and spasm of the circular muscular fibers in the region of the in- ternal os, flexions, polypi and tumors, and vaginal occlusions. Cervical stenosis may be congenital or acquired. If congenital the condition is usually associated with an undersized uterus and the menses are scant; if acquired it is often the result of power- ful applications to the cervix, or it may follow in the train of amputations and trachelorrhaphies. There can be no doubt that spasm of the circular fibers of the cervix is sometimes sufficiently great to cause partial or complete occlusions, giving rise to what has been defined by some writers as "spasmodic dysmenorrhea.” At any rate a certain number of dysmenorrheal cases are met MENSTRUATION AND ITS DISORDERS. 263 with presenting all of the phenomena of obstruction, so far as subjective symptoms are concerned, in which the cervical canal upon physical exploration seems perfectly patulous. Patients thus affected are usually of the neurotic type, and their suffering is best relieved by remedies having a special affinity for the nervous system. Flexions are probably more often the cause of obstruction that anything else. For obvious reasons simple version is not so liable to impinge upon the canal, yet it is entirely possible for a retroversion to so crowd the external os against the anterior vaginal wall as to interfere with the exit of the menstrual dis- charge. Polypi and tumors produce obstruction in a purely mechanical way. Dr. Thomas especially emphasizes the fact that a small polypus, by dropping against the internal os, thus acting as a ball-valve, may cause marked obstruction which is difficult to detect because a probe readily pushes it aside in penetrating the uterine cavity. The most frequent cause of vaginal occlusion is an imperforate hymen. However, slough- ing of the vagina as a sequel of childbirth may result either in complete or partial obliteration of the canal; in complete oblit- eration the menses are, of course, retained. It is worthy of note that certain eminent specialists deny the existence of this form of dysmenorrhea. I heard the late Mathews Duncan, in a lecture delivered at St. Bartholomew's Hospital, London, affirm that so long as the menstrual blood can escape from the uterine canal, no matter how small the opening may be through which it makes its egress, no pain will be caused by the obstruction. In proof of this affirmation he cited the fact that many women possessing a cervical canal not large enough to admit the finest probe, menstruate without the least pain; that women with a "pin-hole os" will sometimes bleed to death; and, finally, that in many of the cases of so- called obstructive dysmenorrhea it is perfectly possible to pene- trate the uterus with a large-sized probe during the intermen- strual period. In our own country Dr. Emmet and others hold nearly, if not identically, the same views. * * For an extended dissertation on this subject see " Transactions of the American Gynecological Society," Vol. VIII, p. 101. 264 A TEXT-BOOK OF GYNECOLOGY. Undoubtedly, in a certain number of cases, the foregoing statements are in harmony with clinical facts; nevertheless, in the vast majority of dysmenorrheas presenting the symptoms of obstruction, the evidences of such obstruction are to be obtained upon physical exploration; besides the symptoms entirely vanish after thorough dilatation. Moreover, an obstruction may exist during menstruation and entirely disappear after the flow ceases; or the obstruction may be of the nature of a polypus which would admit of the ready passage of a sound and which could be detected only by exploring the uterine cavity with the finger. The fact that the spasmodic pains which characterize obstruc- tive dysmenorrhea are followed by a discharge of clots from the uterine cavity, proves conclusively that the blood has been retained long enough for coagula to form, which would be impossible did not some obstruction exist. Symptoms.-The symptoms are those following upon disten- tion of any of the hollow viscera. The uterine cavity, after reaching a certain degree of distention is excited to contraction, and the efforts made to expel its contents result in pain. A gush of clotted blood terminates the suffering, which does not recur until the organ is again distended. The degree of suffering will depend largely upon the persistence of the obstruction, and when it is exceedingly difficult to overcome, the spasmodic pains may continue for some hours before the flow makes its appearance. Diagnosis.-The intermittent character of the pains, coming and going at regular intervals, temporarily relieved by a free discharge of blood which often contains clots, is pathognomonic of obstructive dysmenorrhea. Exploration per vaginam and with the sound will usually locate the seat of the obstruction. The exceptions to this rule already noted should, however, be borne in mind. The spasmodic constriction of the circular muscular fibers may have entirely disappeared before an exam- ination is made, and, indeed, the spasm may not recur at each succeeding menstrual period. A test, to my mind far more con- clusive in determining the part played by the spasm, is the effect of gradual dilatation, which is discussed under the head of treatment. The prognosis is usually favorable, perhaps the most so of any MENSTRUATION AND ITS DISORDERS. 265 of the forms of dysmenorrhea. It is, of course, modified by the existing complications, the most serious of which are inflam- mation of the uterus and its surrounding structures. As long as the ovaries are uninvolved, however, and as long as the condi- tion of the patient does not forbid surgical interference, obstruc- tive dysmenorrhea is probably the most amenable to treatment of all forms. Membranous Dysmenorrhea.-Pathology.-This form of dysmenorrhea is unlike any of the foregoing in that organized material is expelled from the uterus at each menstrual period. This material consists of the menstrual decidua, which is thrown off in sections or occasionally en masse, when the triangular sac represents a cast of the uterine body. There is such a conflict of opinion regarding the nature and cause of this peculiar process as to make it unprofitable at this time to discuss the various theories at length. Instead I shall quote the conclusions of Dr. John Williams, contained in a paper presented to the " London Obstet- rical Society" at a recent meeting. These conclusions are valu- able, both for the reason that Dr. Williams has drawn his deduc- tions from a series of cases which were for many years under his observation, and because he has made a study of the changes in the endometrium during menstruation. They are as follows *: 1. The dysmenorrheal membrane is not the product of conception, but the decidua ordinarily shed as débris with every menstrual epoch. 2. It is expelled as a whole or in masses, in consequence of the presence of an excess of fibrous tissue in the wall of the uterus; this excess is due to imperfect evo- lution at puberty, imperfect involution after parturition or abortion, or is the product of acute inflammation. 3. The membrane is neither the result of an ovarian congestion, nor of an hyper- trophy of the ordinary decidua. 4. The chronic inflammation present is usually the result of the monthly expulsion of the decidua from the uterus, and plays an accidental part only in its production; the inflammation may, however, be independent of the expulsion of the membrane, but it has no causal relation to the formation of the latter. 5. Sterility is not necessarily associated with the affection, but is the result of the condition induced by the expulsion of the membrane from the uterus-inflammation of the uterus and ovaries. 6. The membrane may be expelled without pain. * Edis, "The Diseases of Women," p. 483. 266 A TEXT-BOOK OF GYNECOLOGY. 7. Inflammation of the uterus greatly aggravates the suffering caused by the pas- sage of the membrane along the cervical canal. 8. Great relief may be obtained by curing the inflammation of the cervix, though the membrane continues to be expelled every month. 9. In order to effect a cure, the structure of the body of the uterus must be changed. Symptoms.—These resemble the symptoms of early abortion. The pains are labor-like, bearing down, coming and going with more or less regularity, increasing in intensity until, finally, the expulsion of a large clot, whose nucleus is a piece of membrane, or the expulsion of the whole lining of the uterine body, affords relief. The pain and flow occur simultaneously, and the flow is usually excessive. The expulsive efforts are sometimes so vio- lent as to cause the most intense suffering, and even delirium and convulsions. Patients who have long suffered from this form of dysmen- orrhea are not entirely free from distress during the intermenstrual period. Purulent leucorrhea, because of the existing endo- metritis, is often a persistent symptom. Frequently, too, the victims complain of a general weariness, with more or less constant pain in the abdomen and back, which often extends to the iliac fossæ and down the inner side of the thighs. They look forward to the approaching period with much dread, and the periodical recurrence of menstruation, together with exces- sive drain resulting from the menorrhagia and leucorrhea, sooner or later induce a state of chronic invalidism. It is necessary to differentiate membranous dysmenorrhea from: I, early abortions; 2, casts from the vagina; 3, casts from the bladder and pelvis of the kidney; and, 4, blood polypi.* The prognosis, as to cure, is decidedly unfavorable and must always be cautiously given. Many remedies and expedients of reputed merit have been brought forward, but in due time have fallen into disrepute. A very large per cent. of those suffering from the complaint are, unfortunately, sterile, and even if con- ception occurs abortion is liable to follow. If the views of Dr. Williams are correct, the changes resulting from utero-gestation would undoubtedly be beneficial. Much relief can, however, be * v. page 73. MENSTRUATION AND ITS DISORDERS. 267 afforded by treatment directed toward the existing inflammatory complications, and, indeed, many absolute cures have been re- ported. These have been accomplished, not by any one routine method of treatment, but by almost as many methods as there are cases recorded. A survey of the literature of the subject forces upon one the conclusion that membranous dysmenorrhea, like most other symptoms, requires a careful study of each indi- vidual case. At least a larger ratio of cures are to be found in the literature of the homeopathic than in that of the older school of medicine, and these have been obtained by combining with the local treatment the administration of the indicated remedy. Nevertheless, the number of absolute cures is discouragingly small and shows the necessity of guarding the prognosis even under the most favorable circumstances. THE TREATMENT OF DYSMENORRHEA. General. This will depend, to a certain extent, upon the form of dysmenorrhea which obtains. In the neuralgic, for instance, constitutional measures must be adopted tending to overcome the causes which have induced the neuralgic habit. Thus anemia, chlorosis, rheumatism, malaria, etc., when present, should receive attention. Out-door exercise, a liberal diet, sea bathing, or, if this cannot be practised, a daily sponge bath, are adjuvants of the greatest value in the treatment of the neuralgic diathesis. Flannel should always be worn next to the body, for most neuralgic subjects are exceedingly sensitive to cold. Electricity is of the greatest value in the treatment of this and of nearly all forms of dysmenorrhea.* It must, however, be in- telligently applied and the cases selected with the same discrimi- nating care observed in the selection of the homeopathic remedy. It is not a cure-all," nor should it be so considered. Since using electricity I have discarded entirely the galvanic stem pessary. The remedies more often useful when the neu- ralgic symptoms predominate are: Gelsemium, ignatia, cham- omilla, magnesia phos., coffea, and cimicifuga. The suggestion made by Dr. R. Ludlam, that the remedies be *v. Chapter XI for the technique of application. 268 A TEXT-BOOK OF GYNECOLOGY. administered in warm water, is a wise one, for it is surprising how susceptible these patients are to cold or cold drinks. Heat, in the form of hot applications, hot sitz bath, or the hot douche, is, in any variety of dysmenorrhea, most useful during the paroxysm of pain, especially if the flow is suppressed or scant. In ovarian dysmenorrhea the causes tending to keep up the ovarian irritation should, if possible, be removed. A careful in- quiry into the sexual habits of the patient will often reveal most pernicious practices which, so long as persisted in, make it im- possible to accomplish a cure. Oftentimes a temporary marital separation is necessary. Galvanism, with the positive pole direct, will, I believe, do more for simple ovarian irritation than any other agent. The more prominent remedies possessing a special affinity for the ovaries are: Belladonna, apis, lilium tigrinum, cocculus, and pulsatilla. The congestive and inflammatory forms of dysmenorrhea re- quire measures similar to those useful in pelvic cellulitis and peritonitis. An effort should be made to restore the discharge when it has been suppressed, and actual inflammation should be aborted if possible. The hot douche is probably the most useful agent to accomplish this end, supplemented by such remedies as aconite, belladonna, veratrum viride, pulsatilla, gelsemium, and ferrum phos. While the general measures which have been suggested for the relief of pain will be found useful during a paroxysm of obstructive dysmenorrhea, the radical treatment is very different. The obstruction requires for its removal mechanical and surgical interference. Those of the vagina are to be dealt with according to the principles laid down in the chapter devoted to vaginal oc- clusions. Cervical obstructions due to flexions and other forms of uterine displacement require measures for the correction of the displacement, and much relief may be obtained by a properly adjusted pessary. If the flexion is marked, however, and espe- cially if it is congenital, divulsion is usually necessary before a cure is effected. I have now resorted to the operation so often and am so well satisfied with the results obtained that I deem it best to give at some length my method of procedure. In a given MENSTRUATION AND ITS DISORDERS. 269 case of dysmenorrhea presenting the symptoms of obstruction it is as follows:- If the patient comes to me soon after a menstrual period I make an examination and determine, if possible, the seat of the obstruction. In the great majority of cases it will be found at or near the internal os, at which point the mucous membrane is often exceedingly sensitive. If there is congestion or inflamma- tion of the cervix and uterus, and there usually is, the hot douche once or twice a day is advised, and at least twice a week I place against the cervix and into the fornices of the vagina tampons of boro-glycerid or pure glycerin, medicated as may seem best. These are removed at the end of twenty-four hours and are fol- lowed by the douche. Some three or four days preceding the approaching period, having reduced the congestion by the pre- paratory treatment, I cautiously introduce several sizes of the hard rubber dilators (Fig. 43). This is repeated at least twice before the onset of the period in order to ascertain the effect of dilata- tion. If the effect is good, menstruation will be less painful and, if the obstruction is the result of spasm, permanent relief may be obtained by repeated introductions of the graduated sounds during the succeeding intermenstrual period. Permanent results are, however, the exception to the rule, and the utility of gradual dilatation is restricted largely to determining the probable effect of the more radical operation. It can be done in the office and should not cause anything more than passing pain. If the patient reports her dysmenorrhea for one or more periods relieved by this procedure, and if in due time there is a return of the old suffering, divulsion is indicated. This must be done at her home and every precaution taken to guard against sepsis and inflammation. The bowels should be previ- ously emptied by an enema, and an antiseptic douche adminis- tered shortly before getting on the table. An anesthetic is always necessary. The patient is placed in Sims' posture, a Sims speculum introduced, and the vagina again washed with a I: 3000 bichlorid solution. The cervix is then fixed with a volsella, a sound introduced to ascertain the direction of the canal, upon the withdrawal of which an application of carbolic acid is made as directed for the operation of curetting. The 270 A TEXT-BOOK OF GYNECOLOGY. steel dilator represented in Fig. 44 is next passed into the uterine cavity and the blades gradually expanded. I emphasize the word "gradually" because, if an effort be made to divulse with • too great haste, there is danger of unduly lacerating the tissues. At least ten minutes should be devoted to the operation and the canal dilated to the extent of half, three-fourths, or an inch, depending upon the size of the uterus and the resistance of the tissues. Undersized uteri, with congenital anteflexion, will not bear the same amount of dilatation without injury as will fully developed organs. The amount of force required in different cases will likewise vary greatly, and judgment must be used in applying it. Usually, however, it is considerable—all that can be exerted by one hand. If the tissues are felt to tear it should be lessened. The object is to stretch the tissues to the extent indicated without serious laceration. After the dilatation is completed the uterine cavity is washed FIG. 60. G.TIEMANN &Co. CLEVELAND'S GLASS CERVICAL PLUG. with a 1 : 3000 bichlorid solution and impure carbolic acid again applied to the entire surface. If menorrhagia complicates the dysmenorrhea, I apply the sharp curette to the entire endome- trium. A glass plug (Fig. 60) is then introduced into the uterine cavity, and secured with a silver wire suture. A tampon sprinkled with iodoform is placed against the cervix for the purpose of supporting the parts if vomiting occurs, and the patient is placed in bed. The after-treatment is very simple and consists of a small an- tiseptic douche after each urination, rest in bed for ten days, at which time the plug is removed and the patient is permitted to get up. The tampon is removed at the end of ten hours. This is the ordinary technique followed by me, and it will be seen that it differs somewhat from that of either Goodell or Wylie-the two chief apostles of rapid dilatation in America. First of all, I restrict myself to the graduated dilators for office MENSTRUATION AND ITS DISORDERS. 271. work. I have abandoned entirely the cutting operation as being not only unnecessary, but much less effectual than is divulsion without it. And last, but not least, I have adopted the practice of retaining the plug with a suture instead of endeavoring to keep it in place with tampons. The tampons do not always suc- ceed in maintaining the plug in its proper position; it is necessary to change them often, and they interfere with uterine drainage. If the wire is used nothing further is necessary until the plug is removed, which is easily done. In those cases complicated with rectal trouble,—constipation, hemorrhoids, etc., it is my invariable practice to stretch the rectal sphincter and to remove any morbid condition that may exist in the rectum. Indeed, if the patient complains of vaso-motor disturbances as indicated by cold hands and cold feet, or if she has been unusu- ally nervous, I thoroughly divulse the sphincter ani, even though she has suffered no local distress in the rectum. I cheerfully acknowledge my indebtedness to the teachings of Dr. E. H. Pratt for this practice, and I am thoroughly convinced that the good to be derived from divulsion of the cervix is greatly enhanced by directing attention to the rectal sphincter as well. This treatment is advised with the full consciousness that it is not in accord with the teachings of many specialists, especially of the homeopathic school. Four years ago I was likewise very much prejudiced against divulsion, and advised against it in my classes. It seemed to me then, as it does to many now, a most dangerous and unnecessary procedure-a conviction which was intensified by two cases of cellulitis occurring in my practice, the result of the operation. I found, however, that the average patient suffering from obstructive dysmenorrhea, particularly if the dysmenorrhea were associated with the nervous phenomena already described, remained permanently on my hands, the most that I could accomplish with the ordinary methods being tempo- relief. I then selected my cases with greater care, resorted to proper preparatory treatment, and observed the strictest antiseptic precautions, since which time I have not had one unfortunate re- sult and have hardly failed to relieve permanently a single case rary 272 A TEXT-BOOK OF GYNECOLOGY. operated upon. As regards sterility I have not cured as large a per cent. of my cases as is reported by Goodell, yet the results have been encouraging. In properly selected cases the transfor- mation brought about is simply marvelous, especially if the rec- tal sphincter is treated as well. The menstrual function becomes painless, and the patient is raised from a state of chronic invalid- ism to one of comparative robustness. For the pain incident to membranous dysmenorrhea the same general measures adopted for the several other forms are useful. Dilatation is often exceedingly beneficial, and while it does not put a stop to the membranous formation, it will make its expul- sion much less painful. Dilatation also promotes uterine drain- age and facilitates intra-uterine medication. Whether or not it exerts an influence upon the nutrition of the uterus through its action upon the sympathetic system, is a point worthy of consid- eration. It is not unreasonable to presume that it does. The local applications under which cures have been affected are those of an alterative character. Carbolic acid, iodin, chromic acid, iodoform, persulphate of iron, etc., are the ones which have been most frequently used. The remedies administered in the successful cases recorded in homeopathic literature are: Borax, rhus tox., calcaria, mercurius, bromine, millefolium and guia- cum. Therapeutics. Gelsemium.-Difficult menstruation; the periods are pre- ceded by sick headache and vomiting; congestion of the head, with a dark suffused appearance of the face; large quantities of limpid, clear urine, which relieves the headache; uterus is mark- edly congested and feels as if squeezed by a hand; sharp labor- like pains in the uterus, extending to the hips and back and even down the thighs. Cimicifuga.-SEVERE PAIN IN THE BACK, DOWN THE THIGHS and through the hips, with heavy pressing down; rheumatic diathesis; tenderness of the uterus; great despondency; occipi- tal headache; between the menses debility, nervous erethism and neuralgic pains; insomnia; INFRA-MAMMARY PAINS. Pulsatilla. Neuralgic dysmenorrhea; the menses are delayed, difficult and scanty; menses suppressed or flow intermittent, MENSTRUATION AND ITS DISORDERS. 273 with throbbing headache; pain in the uterus; dysuria; ophthalmia; gastric disturbance with vomiting; morning nausea with bad taste in mouth; worse in warm room; mild, yielding, tearful disposition.* Belladonna.-Congestive and neuralgic type; PAINS COME AND GO IN QUICK SUCCESSION; violent bearing down, as if every- thing would issue from the vulva; violent throbbing headache, better from external pressure. Caulophyllum.-Painful contractions, congestion and irritabil- ity of the uterus; sympathetic cramps in the bladder and rec- tum; spasmodic intermittent pains in the stomach, groins, and even in the chest; rheumatism of the small joints. Magnesium phos.-Menstrual colic; spasmodic pain in the uterus; inability to pass water, from spasmodic contraction; crampy pain in stomach or bowels, with a feeling as if tightly grasped by a band. Calcaria Carb.-Suppressed menses after working in water, with a tendency to cerebral congestion; SCROFULOUS DIATHESIS; coldness of the feet, and very easily affected by the cold air. Apis mellifica.-Ovarian dysmenorrhea; STINGING PAIN IN THE OVARIES; urine is scant and high colored; violent, labor- like, bearing down pains, followed by a discharge of scanty, dark, bloody mucus. Borax.-Menses too early, too profuse and attended with colic and nausea; leucorrhea like the white of eggs; sensation as if warm water were flowing over the parts; membranous dysmen- orrhea. Platina.-PAINFUL SENSITIVENESS AND CONTINUAL PRESSURE IN THE REGION OF THE MONS VENERIS AND GENITAL ORGANS; menses too early, too profuse but of short duration, preceded by spasm with bearing down, and during the flow pinching in abdo- men, with excruciating pains in uterus; melancholia. Secale corn. Menstrual discharge of thin and black or brown fluid, which is exceedingly offensive; tearing and cutting uterine colic, with violent uterine spasms. *"Pulsatilla is at times to be used for menstrual colic, particularly when the menses are dark in color and are delayed. The flow is usually fitful. The patient is apt to be chilly; and the more severe are the pains the more chilly does she become."— Farrington. 18 274 A TEXT-BOOK OF GYNECOLOGY. Cocculus.-Cramp-like pains deep in the bowels, instead of menses, with pressure in chest; vicarious leucorrhea; scanty discharge of black blood. Coffea. Continuous pinching pain in the iliac region; cold- ness and stiffness of the body; neuralgic dysmenorrhea. Colocynth.-Dysmenorrhea relieved by drawing the lower limbs up to the abdomen. Cantharis.-Violent pinching pains in the ovarian region; menses too early, too profuse; blood black and scanty; violent itching in the vagina with dysuria; dryness and feeling of con- striction in throat. Ignatia.-Cramp-like pains in the uterus with lancinations worse from touching the parts; a feeling of confusion in the head, with inability to closely apply the mind; despondency, depression, sadness; CONVULSIONS, FREQUENTLY TETANIC; feel- ing of constriction in the throat, like globus hystericus. Helonias.-Loss of sexual desire and power, with or without sterility; profound melancholia, with marked debility; pain in the back, through to the uterus; menorrhagia. Lilium tig.-Burning, sticking, grasping pain in the ovaries, especially the left; pains extending across hypogastrium, to groin, down the leg; bearing down in uterine region; neuralgia of the ovaries, attended by cutting pains in mammæ. Sepia.-Most useful as an intercurrent remedy; BEARING DOWN SENSATION, WITH A FEELING THAT THE LIMBS MUST BE CROSSED SO AS TO PREVENT PROTRUSION OF THE PARTS; excoriat- ing leucorrhea; "moth spots" on various parts of the body; pain- ful sensation of emptiness in stomach and abdomen. Bryonia. Stitching pain in the ovaries on deep inspiration; menses too early, too profuse, or suppressed, with vicarious bleeding from the nose. Bromine.-Violent contractive spasms before or during men- ses, leaving the abdomen sore; menses too early, too profuse; bright red blood with the expulsion of membranous shreds. Mercurius.-Deep sore pain in the pelvis with dragging in the loins; smarting, corroding, purulent leucorrhea, always worse at night. Nux Vomica.-Contractive uterine spasms; colic with dis- MENSTRUATION AND ITS DISORDERS. 275 charge of coagula; bearing down toward the sacrum; ineffectual urging to stool; DYSMENORRHEA COMPLICATED WITH FLATULENT COLIC AND GASTRIC DISTURBANCE. Viburnum opulus.-Spasmodic and membranous dysmen- orrhea; excruciating colicky pains through uterus and lower part of abdomen, coming on suddenly just before the menstrual flow, lasting sometimes ten or twelve hours. Consult:- Ustilago maydis (membranous dysmenorrhea), sanguinaria, ferrum phos., hyoscyamus, lachesis, rhus tox, zin- cum, cuprum met., aconite, collinsonia, glonoin, graphites, xanthoxylum, and millefolium. Illustrative Cases. CASE XXVIII.-Borax in Membranous Dysmenorrhea.—In a case of membranous dysmenorrhea of some months' duration Dr. A. P. Throop relates the following: As suggested by Prof. Ludlam of Chicago, I prescribed borax I x three times a day, till the next period. The next period occurred the 25th of October. Dysmenorrhea much less, no cast; only shreds, less in size than for months, and the general condition better. The last prescription of borax was given Nov. 21st. In January, 1872, I called at the patient's home, being desirous of knowing the sequel of the case, and ascertained that there had been no more dysmenorrhea, as the period had not again appeared, and the patient was pregnant. As pregnancy and membranous desquamation from the inner wall of the uterus are not compatible, the membranous dysmenorrhea is sup- posed to be cured. On the seventh of August, 1875, she gave birth to a fine, healthy female child, and there have been no symptoms since of any uterine trouble.-N. Y. Homeo. Med. So- ciety Transactions. Case XXIX.—Platina in Dysmenorrhea.—Oct. 23, 1888, I was called to see Mrs. A., æt. 35, nervo-sanguine temperament, and the mother of two children. I found her suffering from dysmenorrhea. She informed me that she had been subject to this trouble ever since puberty; had been under the treatment of four different physicians without benefit, and had grown steadily worse since the birth of her children. Menstruation was regular and normal in quantity and quality, but accompanied by severe spasmodic pains extending from the uterus to the groins and upper part of the thighs. She was extremely nervous, and one foot was in constant motion, beating the bed-clothes with the rhythmical regularity of machinery. While telling her symptoms, she suddenly became rigid and unconscious; the jaws were firmly locked, the forearms flexed upon the arms, the legs extended, and the whole body bent slightly backward. After a few moments she regained consciousness and the regular motion of the foot again commenced and continued until interrupted by another tonic spasm. Her husband stated that during every menstrual period she had from four to ten of 276 A TEXT-BOOK OF GYNECOLOGY. these attacks, varying in duration from five minutes to half an hour. Cimicifuga 3 × was given, but failed to relieve. One week later, a thorough examination was made, but nothing abnormal could be detected except an undue sensitiveness of the internal os during the passing of the sound. Failing to find any mechanical cause, and being firmly convinced that the trouble was mainly hysterical, I now gave Ignatia 30 x. The result was another failure, a discouraged patient, and a determination to stop prescribing on pathological theories and to treat the case according to symptomatic indications. "" After a long search, "tetanic spasms with trismus during the menses was found under platina. Was called again at the termination of the first day of the next men- strual period, and gave platina 30 x in water, every two hours. The spasms ceased at once and have never since recurred. In other respects, the improvement was more gradual; but after taking the remedy during the menses for the next four months, the flow became comparatively painless and the patient was discharged. As nearly two years have now elapsed without a return of the old symptoms, the cure may be con- sidered permanent.—Dr. W. T. Laird, N. A. Journ. of Homeopathy, May, 1891. • CASE XXX.-Viburnum Opulus in Dysmenorrhea.-In my treatment of spasmodic dysmenorrhea, for which variety this remedy is specifically indicated, when the pain sets in, I give Viburnum op. every hour, or every fifteen minutes if the pains are severe. So confident have I been in its almost marvelous powers that I have taken the pains to look up some old cases that I had dismissed years ago as incurable, in order to test this new remedy on them. In every instance so far it has cured these old obstinate cases. Its sphere of action seems to cover nearly the same ground as galvanism. In the last number of the N. A. Journ. of Homeo., Dr. Neftel has a valuable paper illustrating the curative power of galvanism. He gives many illustrative cases, and singularly enough, they all resemble the cases I have cured with Viburnum. I use the Ist.dec. dil.—E. M. Hale, M. D., American Observer, 1874. CASE XXXI.-Viburnum Opulus in Dysmenorrhea.-Two years ago my attention was called to the use of Viburnum Opulus, as a remedy for dysmenorrhea, or menstrual colic. Having a patient who was suffering from this difficulty, I procured the rem- edy for the purpose of a trial. Her symptoms were: an excruciating colicky pain through the womb and lower part of the abdomen, coming on quite suddenly just preceding the menstrual flow. I had failed to do her much good, though caulophyllum had relieved her sometimes. I gave her Viburnum 1st decimal dilu- tion, three-drop doses, to be repeated in half an hour, if not relieved. The first dose relieved her, and she took but two. During the interval of the next period I directed her to take one drop, once a day, and if the pain returned at the next time, to take three drops and repeat as before. Suffice it to say, she had but a slight return of the colic, and now reports herself as cured.-Geo. B. Palmer, M.D., American Observer, 1877. CASE XXXII.-Cocculus in Dysmenorrhea.—I have found this drug useful in cases of regular, irregular, and suppressed menstruation, the flow in most cases having been very profuse, accompanied by severe uterine colic, with bearing down in pelvic region and intense lumbo-sacral pains. In every case where I have found it useful MENSTRUATION AND ITS DISORDERS. 277 in dysmenorrhea, the patient has had a thick, yellow leucorrhea, and in most cases granular degeneration of the cervix. Where uterine disease existed, dys- pepsia, characterized by nausea and flatulence was, with few exceptions, more or less pronounced during the intermenstrual period.-Emma Scott Wright, M. D., Transactions of the Homeo. Med. Society of the State of New York, 1878. CASE XXXIII.—Xanthoxylum in Membranous Dysmenorrhea.-Mrs.—, aged twenty-five years, tall, slender, of light complexion, somewhat stooping, emaciated, anemic; has the appearance of a consumptive. Used to be a rugged, hearty girl; has been married three years; has suffered intensely with dysmenorrhea and has never been pregnant. Menstruation was so painful that she was obliged to remain in bed for several days, from which she would get up so utterly prostrated that she could not rally before her next period came on. Menstruation was normal as to time; the pains were contractive, with great bearing down; the flow was slight; the intensity of her suffering caused her to keep her limbs in constant motion, drawing them up and down in bed, in spite of urgent advice to the contrary. Cocculus and, later, belladonna gave considerable relief. Examination of the napkins used confirmed my diagnosis, viz: membranous dysmenorrhea. Xanthoxylum 2d dec. trituration, three doses each day, acted so favorably that her next period was remarkably free from pain; she was dis- charged in about three months, looking hearty and well. In the course of a year she gave birth to a healthy child, and has been quite free from disease during a period of, now, five years.—Dr. I. N. Eldridge, Medical Counselor, Vol. x. CASE XXXIV.-Membranous Dysmenorrhea. Milfoil Internally and Iodized Phenol Topically.—Mrs. H., the mother of two children; six years after the last con- finement she came to me to be treated for sterility. I learned that about a year ago she observed that the pain during menstruation became very severe; each period more severe than the former. The pains were forcing labor-like, in the back and down the thighs; the blood was dark and clotted, and on the last day (usually the sixth) a mem- branous mass would be expelled, when the pain would cease. An examination of these membranes showed them to be such as are described as pseudo-membranous. The treatment was commenced one week before the menstrual period. It consisted in applying to the endometrium, by means of a probe wrapped with absorbent cotton, a mixture of tinct. iodin, I part; 50 per cent. carbolic acid I part. Internally I ordered Inf. Milfoil, prepared by infusing zij of the dried herb in one pint of hot water, 3j to be taken three times a day. I only made one application topically. She returned to her home in Iowa. One week after her menses ceased she wrote to me that she had no pain during the menses, the blood was normal in appearance and no membrane was expelled. I requested her to report after the next period, if it were not normal. Two months have now elapsed (two menstrual periods) and I have not heard from her. She is probably cured.-E. M. Hale, M. D., Homeo. Journ. of Obstetrics, 1886. Case XXXV.—Guiacum in Chronic Ovaritis with Dysmenorrhea.—Subacute ovaritis of twelve years' duration relieved in 18 days. Miss D., aged 30; nervo-sanguine temperament. She has always been irregular, and when menstruation takes place the pains are agonizing. It is not infrequent that she subsides into an unconscious state after the pains lessen, unless stimulants of various kinds are used. There is an irritable bladder. Both ovaries are sensitive on 278 A TEXT-BOOK OF GYNECOLOGY. pressure; the left one is constantly painful, and is perceptibly enlarged. Gave a suppository of Guiac. morning and evening. Relief was experienced in five days and 36 suppositories gave permanent relief.-M. O. Terry, M. D. CASE XXXVI.-Dysmenorrhea and Spinal Irritation for years. Ovaritis of two years' duration cured in 18 days with Guiacum. Subacute Miss H., aged 24; nervo-bilious temperament. She has constant pain between the shoulders; fulness in the head, accompanied frequently with pain; suffers from stomach derangement and dysmenorrhea. The first five of the dorsal vertebræ, the coccyx, and two inches above it, are sensitive on pressure. There is a dull, aching pain in the left ovary, which has continued over two years. I will not give the names of the "indicated" remedies which were tried and found wanting in her case. The pains across the shoulders, fulness in the head, and nausea, disappeared after a few applications of Paquelin's thermo-cautery had been made to the sensitive ver- tebræ. Other remedies having failed in the ovarian pain, Guaiac. suppositories, 36 in number, given as in the other cases, entirely eradicated it.—M. O. Terry, M. D., New York Transactions, 1883. CASES SHOWING THE BENEFICIAL EFFECTS OF DIVULSION IN DYSMENORRHEA. CASE XXXVII.-M., æt. 26, very tall but well proportioned. Upon presenting herself to me she gave the following history: Began to menstruate at 13, and became regular at 15; more or less dysmenorrhea from the first, and the amount of blood lost has always been excessive. Says that she does not remember when she did not have cold hands and feet. However, she got on very well until entering college, when the hard mental work, together with the exposure and "stair-climbing" incident to her college course, completely prostrated her. The symptoms of obstructive dysmenorrhea kept her in bed during the entire sick week; she became greatly depressed and melan- cholic-so much so that her room-mate feared suicide; subject to frequent attacks of palpitation with syncope; the bowels remained obstinately constipated in spite of the best directed general and therapeutic measures, and the digestion became bad. The amount of blood lost was excessive and the resulting anemia was marked. On July 15 the cervix and rectum were divulsed in the manner heretofore noted, the uterus curetted and the patient left in care of Dr. Luten of Grand Rapids. She re- mained in bed for ten days, when the plug was removed and she was permitted to get up. Notwithstanding the fact that she began the arduous duties of a teacher four weeks later, the improvement was of the most marked character. Six months from the time of the opera'ion she walked into my office looking the picture of health. To use her own words, she said: "I have never before known what it was to be luxuriously well." Menstruation from the very Menstruation from the very first period following the operation was painless and the first premonition of its oncoming is the appearance of the flow. The nervousness and mental depression have entirely vanished, the hands and feet have become warm, the digestion is markedly improved and the bowels are perfectly regular. CASE XXXVIII.-M., æt. 21, referred to me by Prof. D. A. McLachlan, because of some obscure eye trouble which failed to yield to measures directed to the eye, and MENSTRUATION AND ITS DISORDERS. 279 which, from the symptoms complained of, led him to believe that pelvic complications were responsible for much of the difficulty. This patient, so far as physical develop- ment is concerned, is an ideal specimen of womanhood, and yet three days of each month were characterized by intense dysmenorrheal pains with all the phenomena of obstruction. Obstinate constipation was the only disturbance of the gastro-in- testinal canal, and there were no prominent nervous symptoms. Menstruation was scant rather than excessive. The uterus was anteflexed, and the external os of the "pin-hole" type; it was with much difficulty that a fine probe could be made to in- sinuate itself through the internal opening, though there was not the usual sensitive- ness at this point, a fact which explains the absence of many of the nervous symp- toms described in the preceding case. In spite of my best directed treatment I could do nothing more than palliate the dysmenorrheal symptoms. Gelsemium did much good during the attack, and the grad- uated sounds introduced just before the advent of the flow would cause the succeed- ing period to be much less painful; but the improvement, notwithstanding a three months course of local and general treatment, was only temporary, and after an interval of two months the dysmenorrhea became quite as bad as before the treatment. Ac- cordingly on December 23, 1890, I divulsed, under ether, both the cervix and the rectum, operating upon the latter because of the constipation. The patient men- struated at the succeeding period with absolutely no pain, and up to the present time (July 1893) remains almost entirely free from suffering during the menstrual week. Her constipation, while not absolutely cured, is infinitely better, and with the least care in diet gives her no trouble. The eye symptoms are likewise much bene- fited though not entirely relieved. I have in another place remarked upon the ob- stinacy of the ocular neuroses; * when due to pelvic lesions they are usually the last to disappear when such lesions have been cured, and indeed, often will not yield to any treatment. The foregoing cases illustrate in a general way the benefit to be derived from divulsion when indicated. I am sorry that I have not kept an accurate record of all of the cases operated upon by me. I have kept track of all private, as well as most hospital patients, and, with the exception of the two cases already referred to, the results have been universally satisfactory. These two cases were operated upon eight years ago, and each suffered from a sharp attack of pelvic peritonitis as a result. Neither case was suitable for the operation, and at that time I had not mastered the principles of antisepsis. In trachelorrhaphy I divulse, in the majority of cases, at the time of operating, and have seen nothing but good result from the practice. * v, page 190. CHAPTER XIX. MENOPAUSE. Definition. This term is applied to that time of life when the function of menstruation is permanently suspended. It is known, also, as the change of life, the critical time, the turn of life, and the climacteric period. The age at which the meno- pause occurs is most variable. Cases are on record in which menstruation was permanently suspended at thirty-two, and Dr. T. A. Emmet has reported a case in which the function recurred regularly, although the woman was seventy-two years old. These ages are the extremes, the climacteric changes being inaugurated in the larger number of cases at about forty-five. Such extremes may be due either to idiosyncrasy, to rapid child- bearing, or to some constitutional disease. Thus, there are certain families in which the climacteric period occurs early, or, it may be, late in life. Rapid child-bearing has a tendency, by depressing the system, to hasten the change; and constitutional diseases may either precipitate or prolong the menopause, as they may precipitate or delay puberty. There is a popular error, which is by no means limited to the laity, that it is necessary for a woman to undergo a certain amount of suffering while passing through this period. Much harm has resulted from this erroneous impression. A woman, perfectly healthy in all respects, should not suffer inconvenience; nevertheless, there are very few instances where the change of life is passed through without more or less discomfort. If, however, the function of menstruation has been perfectly normal, if there exists no local or constitutional disease, in short, if a woman is perfectly healthy, the climacteric change should come to her as a pleasant advent rather than one of suf- fering. The doctrine of necessary suffering at this time, and especially 280 MENOPAUSE. 281 the doctrine that it is perfectly natural for excessive menstruation and metrorrhagia to take place, has more than once led to the neglect of various affections which are responsible for the delayed cessation. Thus, cancer, fibroid tumors, fungoid degeneration of the endometrium, and polypi are permitted to progress indefi- nitely, the woman continuing to flow long after ovulation has ceased. Usually, when menstruation is prolonged after the age of fifty, it is because of local disease, and a thorough examina- tion should be instituted. Anatomical Changes.-The anatomical changes contrast markedly with those occurring at puberty. Thus, the vascularity of all the pelvic organs is increased at puberty; whereas the vascularity is diminished after the menopause. Physiological hypertrophy of these organs characterizes puberty; physiolog- ical atrophy is instituted by the menopause. The ovaries become smaller and in time are converted into contracted masses of fibrous and cellular tissue; the Graafian follicles shrivel and contract. Like changes take place in the Fallopian tubes, the uterus and the vagina. Indeed, all of the sexual organs undergo senile atrophy and are reduced to a rudimentary state. This rearrangement may take place suddenly or gradually, requiring much more time in some women than others. During its progress the line of demarcation between the physiological and pathological may be very hard to define. Symptoms. As already stated, no distressing symptoms should attend the menopause if the patient is in a perfectly healthy condition; but, as there are few women absolutely free from distress during the menstrual period, though this function should be perfectly painless, so there are few women absolutely free from discomfort while the system is undergoing climacteric changes. The degree of suffering will, however, depend, in no small measure, upon the temperament of the patient, a nervous woman suffering infinitely more than one of phlegmatic tem- perament. The character of the symptoms will also depend upon the habit of the patient. If she be plethoric, for instance, the phe- nomena will be those attending plethora,-congestion of various 282 A TEXT-BOOK OF GYNECOLOGY. parts of the body, headache, palpitation, hemorrhages, etc.; if chlorotic or anemic, she will suffer from the symptoms in- cident to the depravity of nutrition. Headaches are of frequent occurrence and may be either con- gestive or anemic in character. The disturbance of the vaso- motor system gives rise to flushings and an irregular distribution of blood to various parts of the body. Alternate coldness and heat of the hands and feet are likewise of common occurrence. There may be either irritability, or torpor and sluggishness, of the gastro-intestinal canal. If irritability, there is often nausea, vomiting, and diarrhea, the result of a hyperesthetic condition of the mucous membrane. One of the worst cases of irritable rectum with which I have ever met occurred during the climacteric period. If there be sensory paralysis of the mucous membrane, the most obstinate constipation may ensue. Flatu- lence is likewise a frequent result of the gastro-intestinal dis- turbance. So great is the accumulation of gas at times that pregnancy is suspected. Indeed, all of the subjective symptoms of pregnancy may be so faithfully imitated as to make the diag- nosis extremely uncertain. The The processes of elimination are more active in every way. skin eliminates more readily, and perspirations, at times morbid, often occur. All of the salts of the urine, especially the urea, are in excess. The quantity of carbonic acid eliminated is also increased. Very often, too, the secretions of all of the mucous membranes, particularly those of the genital tract, are exaggera- ted. Occasionally vicarious leucorrhea will continue, becoming increased at certain intervals, for a long time after the last appearance of the flow. Let it not be forgotten, however, that a leucorrhea more or less persistent is usually the result of local disease, and when it does not abate in due time an examination should not be too long delayed. The first symptom of carcinoma may be a leucorrheal discharge, and since the patient is passing through the so-called cancerous age, any suspicious symptoms should be carefully investigated. The nervous symptoms not infrequently predominate, though the patient may not suffer from an excessive loss of blood. Indeed, they often persist after menstruation has ceased entirely, MENOPAUSE. 283 and when the local evidences of disease, so far as tissue changes are concerned, are wanting. Dr. Wylie has called attention to the fact that there often exists, in these seemingly obscure cases, a hyperesthetic spot at the internal os, or at some portion of the fundal mucous membrane. I have frequently demonstrated the presence of this hyperesthetic spot, not only in women passing through the change of life, but in young girls victims of dys- menorrhea. A sound passed into the uterine cavity will give rise to the most exquisite pain when it comes in contact with it; and I have had patients nearly jump from the examining table when the tender point was touched. I remember one case in particular, in which I could produce a most intense supraorbital neuralgia by passing the sound. The cause of the hyperes- thesia is uncertain, though it is probable, as suggested by Wylie, that it is the result of previous inflammation. The fact that this localized hyperesthesia is productive of innumerable reflex symptoms is clearly proved by the effects of treatment: when the diseased area is destroyed, the symptoms will frequently vanish as if by magic. The changes attending the menopause are indeed critical in character, and the patient's future health will depend, in no small degree, upon the care which she receives while passing through this period. Many existing diseases will entirely disappear. This is especially true of the various chronic inflammatory affec- tions. Indeed, metritis may be incurable so long as menstrua- tion recurs at each month to excite congestion. The various inflammatory affections of the ovaries are likewise often incura- ble while the function of ovulation continues; and of course the different forms of menstrual irregularities disappear with the cessation of ovulation. Fibroid tumors usually stop growing after the change of life, and often undergo a more or less decided atrophy. On the other hand, certain other diseases are either aggravated or precipitated by the climacteric changes. As already intimated, the several forms of cancer make their appearance at this time oftener than at any other. Nervous affections of various kinds frequently date from this period. Hysteria, epilepsy, paralyses, apoplexy, and especially insanity, are often fanned into existence " 284 A TEXT-BOOK OF GYNECOLOGY. by the conditions attending the change of life. As suggested by Ludlam, there is a tendency for diseases which existed when the function of menstruation was inaugurated, and which were held in abeyance by it, to recur at the cessation of the function. Such diseases are the various skin and bowel affections, tuber- culosis, and the neuroses. Skin affections are particularly liable to be brought to the surface, and a careful inquiry into the clini- cal history will frequently reveal the fact that the patient suffered from the same affection during girlhood. In conclusion, then, a woman should pass through the meno- pause, if perfectly well, without serious inconvenience. When the system is greatly disturbed, it means that something is wrong. The disturbing cause may or may not require for its removal local measures. The inconvenience may be so slight as hardly to overstep the boundary of the normal, and no attention other than perhaps a little general advice need be given the case. On the other hand, if the patient suffers unduly, there is no period of her life during which she more needs judicious care and treatment. Treatment. There are certain general hygienic principles which are applicable in all cases. The frequent use of the sponge bath will keep the skin active and promote elimination. At least twice a week the patient should take a hot bath, remaining in the water for from twenty to thirty minutes. After either the sponge or the tub bath, the skin should be well rubbed down with a Turkish towel. The amount of physical exercise to be prescribed in a given case must depend upon circumstances. Plethoric patients are nearly always benefited by outdoor exercise, short of fatigue -weariness or exhaustion is always injurious. Where there is marked debility, walking, or, indeed, any form of exercise, may be impossible. The muscular system should, however, receive attention, and if the patient finds it difficult to walk, massage may be advantageously substituted. Late hours, especially in nervous cases, should be avoided. Insomnia is often a prominent symptom and every precaution should be taken to promote sleep. Plenty of fresh air is the best natural soporific and the sleeping apartments should, there- MENOPAUSE. 285 fore, be well ventilated. Excitement during the evening is most injurious. Many times a warm bath or a hot vaginal douche immediately before retiring, will afford a good night's sleep. Tilt maintains that thin, nervous women cannot sleep too much. He recommends, when insomnia is very troublesome, that the patient eat immediately before retiring, or have at her bedside some light broth or bouillon to take during the night. Sexual hygiene is likewise of much importance. Intercourse should take place only at long intervals. When there is an in- crease in the sexual appetite it means, in a large majority of cases, that there is some local disease which requires attention. Tilt emphasizes the fact that women passing through the climacteric period should not marry. He cites several cases coming under his own observation where the most disastrous consequences followed immediately upon marriage. Much tact is often required in the management of the mental . and moral symptoms. There is, many times, a marked perver- sion in the moral sensibilities. Women previously cheerful and contented become irritable, taciturn and unreasonable. It may be necessary to remove a woman thus affected from home sur- roundings. A change of scenery, association, and climate is often most beneficial. As regards local treatment, any of the various lesions which have been enumerated should, if present, be removed. The treatment of the hyperesthetic spot, when it exists, consists of the application of a ten per cent. solution of cocain directly to the parts, followed by the introduction of a hard steel dilator and a moderate degree of divulsion. Pure carbolic acid is then ap- plied to the endometrium, after which a boro-glycerid tampon is introduced into the vagina. It is surprising how quickly this treatment will relieve many of the reflex nervous symptoms. hemorrhage is a prominent symptom the uterine cavity should be carefully explored and, if necessary, the curette applied. Finally, lesions of the rectum should always be looked for. It is my practice to divulse the rectum also when the cervix is forcibly divulsed for the purpose of relieving nervous symptoms. If I know of no class of symptoms which will respond more quickly to the properly selected remedy than will the various 286 A TEXT-BOOK OF GYNECOLOGY. disturbances and phenomena incident to the menopause. It is to me most surprising that the specialists of the older school have never learned to use intelligently, at least some of the remedies which the homeopathic school find so useful in relieving the innumerable phenomena characterizing this period. Ringer, Bartholow and others have hinted at the utility of many of them in the condition under consideration, but the specialists have largely ignored the suggestions of these writers. They con- fess their inability to relieve the flushes, the headaches, the local congestions, etc., without placing the patient under the action of remedies the continuous use of which they themselves admit to be pernicious. At the same time I desire to insist upon the necessity of looking for local causes when the internal remedy 'fails to relieve the symptoms for which it is prescribed. If selected with care it will do all that it is possible for internal medication to accomplish, and when it fails in its object it is usually because of the existence of some local or mechanical cause which requires for its eradication local or mechanical measures. Therapeutics. Sanguinaria.—There is much irritability and anger; head- ache begins in the occiput, extends upward and settles over the right eye; distention of the veins of the face with excessive redness, or circumscribed redness of one or both cheeks; FLUSHINGS, lassi- tude, torpor and langour; not disposed to move or make any mental exertion; symptoms all aggravated during damp weather. Lachesis. Chills at night and flushes of heat during the day; patient feels much depressed in early morning; MUCH heat AT THE VERTEX; globus hystericus with great sensitiveness of the larynx; SYMPTOMS worse after sleep. Sulphur.-Flushes of heat followed by cold spells; cold feet; bleeding hemorrhoids; constitutional bias prominent. Pulsatilla.-Tearful temperament; shooting neuralgic pains in various parts of the body; milky, thick leucorrhea with swollen vulva; pressure in pit of stomach after every meal, with vomiting of food; all symptoms relieved in open air. MENOPAUSE. 287 Jaborandi.-MORBID PERSPIRATIONS; MARKED SALIVATION; suffusion of the face and the entire body; nausea and vomiting. Sepia.—ALL GONE, SINKING SENSATION AT PIT OF STOMACH; moth-colored spots on the skin, especially on forehead and over bridge of nose; unnatural perspirations, particularly in axillæ ; anemia from profuse menstruation; leucorrhea yellowish or greenish and causing much itching; hysterical twitchings and spasms. Amyl nitrite. This remedy is, I believe, one of the most useful of all remedies in the flushes of heat so often present during the climaxis. They are attended by throbbing and a sensation of intense fullness in the head; there is often a choking, restricted feeling about the throat which lachesis fails to relieve; much throbbing in the ears. Glonoin. Congestion about the head with much FULLNESS AND THROBBING; flushes of heat with vertigo; alternate redness and paleness of face; symptoms all aggravated in a warm room and ameliorated by walking in the cold air; frequent attacks of fainting. Ignatia.-Desire to be alone; changeable disposition, though sadness predominates; clavus hystericus; throbbing pain in the occiput. Consult:-Aconite, caulophyllum, cimicifuga, belladonna, gelsemium, argentum nit., and coffea. Illustrative Cases. CASE XXXIX.-Reflex Nervous Symptoms Cured by Divulsion and the Applica- tion of Carbolic Acid.—In the spring of 1880, a rather thin, wiry woman was sent to me by Dr. Greenough, of this city. She said that she had dysmenorrhea when young, but had not had any special uterine disease that she was aware of. She had married when thirty, and about five years later her menstruation had ceased, and had not shown itself, except two or three times when she had a scanty flow, for the past two years, and that during this time she had had hot flashes and all kinds of nervous symptoms, had taken all kinds of remedies, but that she was growing thin, sleepless, etc., and that Dr. G. advised her to have a local examination. I found the vagina and uterine appendages normal, so far as I could discover; the uterus was a little below the normal size, but not as small as is usual two years after the menopause. It was ante- flexed and in about the normal position. In and near the os the mucous membrane had a peculiar coppery or yellowish-stained appearance, which I had now and then seen about the cervix uteri of women past the menopause. In passing a sound I 288 A TEXT-BOOK OF GYNECOLOGY. found the os internum contracted, and as the sound passed into the cavity of the fundus it gave exquisite pain, and reminded me so forcibly of the condition of the uterus so very common in young women suffering from dysmenorrhea due to imper- fect development that I made up my mind to give it the same treatment as I was then using for the relief of dysmenorrhea. I gave the usual preparatory treatment, and dilated the cervix with a steel dilator, and applied, by means of an applicator and cervical protector, pure carbolic acid to the endometrium. I warned her, as I do in cases of dysmenorrhea, that the first dilatation might be quite painful and increase her nervousness for a day or so, but that the second would not be so painful, and the third still less so, and that if this treatment helped her I could probably cure her. The dilatations were made about a week apart. The result was magical; her nervous system quieted down, she could sleep, eat well, and she steadily improved in general health. Twice within six months she had a slight return of the reflex symptoms, and the dilatation and applications were repeated with equally good results. In a year's time she had gained twenty-six pounds in weight, and claimed to be perfectly well. Since then I have treated a large number of cases suffering from reflex nervousness at and soon after the menopause, by dilatation and applications, and with most excel- lent success. In two or three of these cases the nervousness was extreme, and the patients had been through all kinds of treatment in the way of medication, water cures, and even "rest cures," without permanent relief; yet they were cured in a very short time by dilatation and intra-uterine applications.—Wylie. CASE XL.-Dipsomania.-Like B. de Boismont, I have several times seen tem- perate women have a craving for spirits only at the menstrual epochs, the craving subsiding with the flow; and the same desire has been noticed in pregnant and puer- peral women. Esquirol and H. Royer-Collard have met with women in good circum- stances, who all through life had been temperate, but who at the change were sud- denly seized with an irresistible desire for brandy, which again became disagreeable to them when the critical period was passed. This impulse is akin to the well known longings of pregnancy, and those who yield to it know that they are doing wrong, struggle against it, but are sometimes overcome. It is easy to understand how such impulses should be rife at all the periods when the ganglionic nervous system is in a state of perturbation, and when anomalous sensations at the epigastric region indicate morbid action in the central ganglia. It can be cured by proper treatment.— Tilt. CASE XLI.—Kleptomania.—Drs. Taylor and Marc have known patients who, pre- vious to puberty or to disordered menstruation, were conscientious respecters of rights of property, but who, though in affluence, would steal, at all risks, at the critical periods. of life. Dr. Marc mentions a rich lady who, during pregnancy, could not resist the temptation of stealing a chicken from a cook shop. I have already described cases of this description caused by the change of life, and I believe they are of more frequent occurrence than is supposed, although the sense of acting wrongly is still present to the mind of those who yield to this impulse.-Tilt. CASE XLII.-Nervous Aphonia.—This is a rare affection, but I have had a good opportunity for studying the case of a lady, at the change of life, who, after losing her husband, came to town and settled in Belgravia. Though she had not been hitherto subject to nervous affections cold, over-exertion, or worry, would suddenly deprive her of her voice for a few days, and this sometimes occurred without apparent cause. MENOPAUSE. 289 The nervous nature of the ailment was shown by the sudden coming and leaving of the aphonia, and by the effect of change of air; for a drive in Regent's Park or to Hampstead would often restore her voice to its natural tone. On leaving town to reside in the country, she has ever since enjoyed a comparative immunity from this complaint. Sometimes a potion containing ether speedily dispelled the aphonia. In two cases I found sudorifics useful, the permanent return of the voice coinciding with a marked determination to the skin. Cerise speaks in favor of emetics for nervous aphonia, and I have witnessed their sudden good effects, but the best treatment is the direct application of electro-magnetism, either to the tongue or to the larynx, by means of Dr. Morrell Mackenzie's galvanizer. The shock makes the patient scream, the spell is broken, and she is immediately cured.— Tilt. CASE XLIII.—The Menopause Delayed by Fungosities of the Endometrium.—This patient was married, and the mother of five children. After the birth of her last child she suffered from uterine leucorrhea, probably caused by endometritis. She had fair health in spite of that, and menstruated regularly until she was forty-six years old, and then the menstrual flow became more profuse. This continued intermittently for nearly one year, when the menses came more frequently, lasted longer, and the flow was quite profuse. Her health failed gradually; she became anemic, weak, low-spirited, and nervous. Though her flesh remained (she was rather stout), her strength was greatly reduced. Her family physician gave her the usual remedies-lead and opium, ergot, cannabis indica, and aromatic sulphuric acid-in the hope of controlling the flow, but without effect. Finally, she consented, with some reluctance, to an examination, when a large number of polypoid growths were found in the cavity of the uterus. These were removed with the curette, and the flow stopped for six weeks; it then returned for a few days, but was not very free. There was a return of the menstrual flow in two months, very scanty, and another in three months, and that was the end of it. She was then forty-eight years old. After the removal of the fungous growths with the curette, her health improved under tonic treatment, and, when last seen, at forty-nine years of age, she was quite well.—Skene. CASE XLIV.-Diarrhea and Morbid Perspirations.-Catherine M., aged fifty-three, tall, thin, and pale, menstruated very abundantly at fifteen years of age; was regular from the first, and continued so for three or four days every three or four weeks, with so little suffering that "she never felt them come or go." She married at thirty-three, miscarried three times, and bore five children, the last at forty-seven; and menstrua- tion, which had been irregular a year previous to conception, never returned after that event. The patient was generally relaxed during the menstrual epochs, and during her last pregnancy, and after her confinement, she frequently had three or four stools a day, without pain or loss of appetite, after which diarrhea came on every three or four weeks, with flushes and drenching perspirations. For the last twelve months she was relieved six or seven times a day, until lately, when the bowels only acted once in two days, and on this account she had suffered much from heat, flatus, nausea, oppression at the pit of the stomach, and want of appetite, although her tongue was clean and healthy. When the action of the bowels became freer, the patient got well.- Tilt. 19 CHAPTER XX. VICARIOUS MENSTRUATION. Definition and Synonyms.-The term vicarious menstrua- tion is applied to the discharge of menstrual blood through some channel other than the uterus. Flamant uses to define this con- dition the word xenomania, which expresses "the idea of the menses taking a wrong course." Barnes proposes, when the menses escape from the wrong place, the term ectopic menstrua- tion. Finally, Dr. Bedford-Fenwick suggests that the term vicar- ious hemorrhage more clearly defines the phenomenon than does that of vicarious menstruation, because the vicarious discharges do not possess the characteristics of true menstrual blood. The dearth of modern literature bearing upon the subject is something surprising. Gendren, Parrot, Whitehead, and Courty, of the older authors, deal with it somewhat in detail and have recorded several cases of so-called vicarious menstruation, some of which will hardly stand the test of modern scientific investi- gation. More recent and reliable ones are recorded by Butler,§ Rein,§ Chapman,§ Hardon,§ Cooper,§ Barnes,* Routh,* Fen- wick,* Mansell-Moullin,* Mitchell,† M. Guépin, and many other writers. Some of these cases are referred to in detail at the end of this chapter. By far the most learned and scientific dissertation yet pro- duced in any language treating of vicarious menstruation was presented in 1886 to the British Gynecological Society, by Robert Barnes, m. d., F. R. C. P., and published in the Transactions of that year. The discussion that followed was equally learned, making with the essay a most valuable and elaborate contribu- * British Gynecological Journal, Vol. 11. † American Journal of Medical Sciences, Vol. xxx, p. 83. † Medical Times and Gazette, 1862, p. 338. ? Annual of Universal Medical Sciences, 1889. 290 VICARIOUS MENSTRUATION. 291 tion to the literature of the subject. I shall in this chapter endeavor to reflect the views of the justly celebrated essayist, giving his conclusions in full. Barnes was prompted to collect the data therein given for the reason that Dr. Wilks, a writer equally sagacious, disputed most emphatically and energetically the existence of so-called vicari- ous menstruation. The former's arguments are so largely based upon physiological and pathological phenomena and analogies, which at times require most careful study in order to compre- hend the author's meaning, as to prompt me to create from them the following schema. This will be sufficiently amplified to make it clear, and will, I think, aid the reader very materially in following the arguments set forth :— VICARIOUS MENSTRUATION. I. Phenomena of normal menstruation, . II. Analogy between menstruation and pregnancy, • • • (a) Increased nervous tension and mo- bility; (b) Increased vascular tension; (c) Increased temperature; (d) Increased excretion of urea. (a) Ovulation the beginning of both; (6) Mucous membrane-similar changes in both; (c) Exalted nervous tension-present in both; (d) Casting off of useless decidua in menstruation is analogous to labor. The object of normal menstruation is, therefore, to discharge superfluous material and energy not required for gestation. III. Physiological substitutes for menstru- ation, • • IV. Pathological substitutes for menstru- ation, • V. Theories, . (a) Pregnancy-hence a form of vicari- ous menstruation; (6) Lactation—hence a form of vicari- ous menstruation; (c) Building up of new tissue. (a) Vicarious diarrhea or leucorrhea; (6) Serous effusions; (c) Ectopic, or vicarious discharge of blood. ((a) Plethoric-increased intra-vascular pressure. (b) Neurotic- proofs, (c) Becquerel's and Scanzoni's theory, Influence of the emotions upon menstruation; (2) Influence of nervous system upon the circulation; (3) Frequency of vicarious menstrua- tion in neurotic subjects. Abnormal structure of the vessels and organs to which the flux is directed. 292 A TEXT-BOOK OF GYNECOLOGY. Dr. Barnes says: "We are met at the outset by this difficulty: physiologists are not agreed as to what causes or constitutes normal menstruation. This difficulty may be evaded without seriously affecting the argument, by putting aside the controversy as to whether the menstrual flux is caused by the maturation of the ovules. My own observation inclines strongly to the conclusion that ovulation is the immediate cause of the flux. * * Briefly, then, menstruation consists in the periodical discharge of blood from the uterus. This, the most conspicuous objective phenomenon, is, however, only one act in a complicated process, of which the genital system is the focus, but upon which the entire organism is at work.” by The phenomena of normal menstruation are— I. Increased nervous tension and mobility.-This is evidenced "exalted psychical, emotional, and reflex action." 2. Increased vascular tension.—This gives rise to “turgescence of the capillary and venous systems," as is demonstrable by the sphygmograph. "The vascular tension falls quickly when the menstrual blood-flow sets in."* 3. Increased temperature.-Repeated observation shows that the temperature is increased before and during the menstrual flow at least .5°. The urea is also increased. The writer next draws a most ingenious analogy between menstruation and pregnancy. He says:-"Assuming that the primum mobile in either case resides in the ovary; the first step is ovulation, or the ripening of an ovum and the depositing of it in the uterus. But the work of preparation begins in the uterus long before the extrusion of the ovule from the ovary. In response to the development of the ovum, nerve force and blood are attracted to the uterus, the whole organ swells, becomes heavier and more sensitive, softer, from the permeation of its walls by fluid; the utricular glands of its cavity enlarge, secrete "The volume of blood is also increased. Andral and Gavarret showed that the quantity of carbonic acid exhaled by the lungs rises until the age of thirty in men, but only until puberty in women; moreover, that in women it falls off as soon as men- struation is established, to increase again after the menopause. If for any cause the menstrual flow is arrested for several months, as by pregnancy or lactation, the quan- tity of carbonic acid is increased, as after the menopause.”—Barnes. VICARIOUS MENSTRUATION. 293 more freely; the mucous membrane swells, grows, is developed into a thick, soft, pulpy membrane, the decidua. This process is the representation-to this point-of pregnancy. It is marked by certain signs, more or less distinct, in different cases. But in all there may be observed exalted nerve-tension, expressed by greater emotional and reflex mobility, sometimes revealed in neuralgia, in vomiting, and even convulsions. There is increased central nervous irritability, and there is the eccentric source of irritation in the uterus. Concurrently, there is observed a marked increase of vascular tension. The pelvic vascular region espec- ially feels the attractive force of the uterus. Then there comes a casting-off and casting-out of the useless decidua ; the process is traumatic. This is the analogue of labor. The developed muscular fibers contract under the influence of the intensified diastaltic function. Hemorrhage attends. The mimic labor over, the blood-current and nerve energy are lowered, and the excess diverted from the pelvis, and for a time the ordinary equilib- rium of the economy is restored. The uterus returns to its wonted state, and the breasts become quiescent. This history presents points of similitude with that of gestation at every stage." Certainly the analogy between the two processes is traceable in detail and without any great stretch of the imagination. Ovulation has for its final object conception. If this does not take place then menstruation occurs as a substitute for both con- ception and parturition, during the last stage of which may be seen the analogue of puerpera; the energy and material pre- pared for the missed pregnancy is now superfluous and is dis- charged. Since, then, the object of menstruation is the discharge of superfluous material and energy," it necessarily follows that when the function is held in abeyance by physiological causes there must be physiological substitutes for menstruation. The causes which physiologically suspend the function are pregnancy and lactation. During gestation the blood which would be lost in the menstrual discharge, were menstruation not interrupted by pregnancy, is used for structural purposes in the development of the fetus. Lactation is likewise a substitute for menstruation, 294 A TEXT-BOOK OF GYNECOLOGY. for, commonly, menstruation is suspended during the usual period of lactation. A third substitute for menstruation is the building up of new tissue. This is why women so frequently be- come fleshy after the menopause. The material elaborated for menstruation is no longer needed for that purpose; nor can it be utilized for either gestation or lactation-hence the general deposition of fat. It must be observed, in passing, that neither pregnancy nor lactation always suspends menstruation. For some reason ovu- lation (I assume that ovulation is the primum mobile of menstrua- tion) is not interrupted by gestation; or recurs during lactation. In this way true menstruation, i. e., a periodical discharge of blood from the uterine cavity, takes place, which differs in no wise from true menstrual discharge. For the first three months of gestation this is entirely explicable, for the decidual cavity is not always perfectly closed. Of course, it is not difficult to un- derstand the processes of menstruation during lactation; the uterine mucosa has returned to its normal state and, if the men- strual wave is set in motion by ovulation, it is ready to undergo the changes incident to menstruation. Hemorrhage occurring at these periods, however, does not always proceed from the uterine cavity. It may come from the vagina or the cervical canal—the tendency to an overflow from some point being too strong to be restrained. Barnes records one case in which the villi of the vaginal portion were bared, tumid, and vascular, so that malignant disease was strongly suspected. The cervix re- turned to its normal condition after labor. I have seen a case very much like this, the patient menstruating regularly up to the time of her miscarriage at the end of the fourth month. Projecting from the posterior lip was a vascular growth as large as a hickory nut, which a microscopical examination proved to be simple hypertrophy of the mucous membrane. After the miscarriage the hypertrophied tissue entirely disappeared. "These hemorrhages," says Barnes, "are conservative in de- sign. * * They relieve systemic and local hyperemia. In this respect they resemble some cases of abortion, which may be regarded as a protest of nature against the continuance of a dangerous pregnancy; unless relief be found in this way, * * VICARIOUS MENSTRUATION. 295 vital organs may be struck, and we may have fatal cerebral or lung apoplexy." I will now allude to the evidence which justifies a belief in the existence of vicarious menstruation. I. Clinical observation.-Not all of the cases recorded by Barnes and other writers will bear close investigation, but there is, I believe, sufficient reliable clinical evidence to convince any unprejudiced investigator that vicarious hemorrhages do occur. 2. A profuse hemorrhage from distant organs frequently causes catamenial suppression.-This shows the part played by increased vascular tension, which characterizes normal menstruation. If this tension is relieved by an escape of blood from any part of the body remote from the uterus it may suspend, temporarily, menstruation-in fact, is a substitute for menstruation. 3. The various organs of the body are constantly assuming vica- rious or supplementary functions.-I again quote in detail from Barnes: "The skin, the kidneys, the lungs, the liver, the glan- dular system, intestinal and other, are constantly doing recipro- cal work. That obstructed or arrested menstruation, then, should be supplemented or helped by other organs than the uterus is in strict accordance with the fundamental laws of phy- siology. There is a solidarity in the organism, binding the con- stituent organs into unity, and making them work with one con- sent. Reasoning from this basis we shall be prepared to under- stand that menstruation is not simply a function of the uterus and ovaries, but a systemic function. Menstruation, or an equivalent substitute, must be performed." We have seen that the physiological substitutes for menstrua- tion are pregnancy, lactation, and the building up of new tissue. If the material elaborated for these several purposes is not util- ized for the same; or, if it is not discharged as superfluous in the form of menstruation, we may expect a more or less successful attempt at one or more of the following pathological substitutes: 1. A vicarious diarrhea or leucorrhea.-Both are usually very watery, the leucorrhea consisting of serum or mucus. 2. Serous effusions.—These occur in the substance of organs, in serous cavities, or in connective tissue. In chloro-anemic 296 A TEXT-BOOK OF GYNECOLOGY. girls, anasarca, more or less general, is not of infrequent occur- rence. 3. Ectopic or vicarious discharges of blood from any and every part of the body.-The most common seat of the discharge is the nose; next in frequency come the stomach and lungs. It may, however, proceed from any part of the body, selecting by prefer- ence, as we shall see later on, some site previously weakened by disease. Should the system not be relieved by the foregoing substitutes there may arise any of the various neuroses, as neuralgia, migraine, hysteria, epilepsy, apoplexy, etc. To classify these affections as pathological substitutes for menstruation, as does Barnes, strikes me as carrying the philosophy of analogy too far. They are rather the sequelæ of an arrested function, and hardly come within the range of either an analogue or a homologue of men- struation. I think that the arguments produced prove pretty conclusively that menstruation, or its equivalent, must be performed, or the system will bring into action reciprocal functions. It now becomes necessary to analyze the various theories which have been put forth as explanatory of vicarious menstruation. They are the following:- 1. The Plethoric Theory.-This is one of the oldest, and is based upon the well-known fact that intra-arterial pressure is always increased before menstruation. It implies the necessity of relief through some channel-if the usual avenue is closed, vent is found at the locus minoris resistentiæ. Should the ordi- nary safety-valves fail, and the blood find no external outlet, it may escape, as we have seen, into the brain, the liver, the kid- ney, the spleen, or, indeed, into and from any of the internal organs. Parrot objects to this theory upon the ground that most of the victims of vicarious hemorrhage have been chlorotic, in which affection the red blood-corpuscles are diminished-the very reverse of true plethora. In refutation of Parrot's objection, Barnes very appropriately remarks that "increased vascular turgescence and exalted vascular pressure are phenomena found VICARIOUS MENSTRUATION. 297 with diminution of the red globules." Such a state exists in pregnancy, for instance, when the watery element of the blood is increased with correspondingly increased peripheral vascular tension. 2. The Neurotic Theory.-The chief champion of this theory is Parrot, whom I have just quoted. Parrot has applied to these hemorrhages the term "neuropathic." In support of this theory it is adduced that menstruation may be suppressed by emotional causes, as anger, fright, joy, etc., the suppression being frequently followed by hematemesis; that the subjects of vicarious hemor- rhage are nearly, if not quite, all victims of some nervous disor- der; and, finally, that in those cases where the discharge continues after the removal of such disorder, a habit induced by the period- ical repetition is sufficient to perpetuate the menstrual escape of blood. (Whitehead.) The influence of the nervous system in the perversion of the function of menstruation cannot be questioned. I have endeav- ored to make this clear in the chapter devoted to the General Pathology of Gynecological Diseases. That local hyperemia and anemia may be induced by nervous influences is well shown in the phenomena of blushing and the pallor of fear. The nervous system exerts a controlling force upon the circulation which, if suspended or diverted, may cause intense congestion in some part or organ of the body, with resulting hemorrhage. But, as observed by Barnes, "If we must admit the fact that the blood could not move in the vessels unless under the influence of nervous energy, we must equally admit that there would be no nervous energy were it not for the nutrient and stimulant energy of the blood." There is, therefore, a concurrent and mutual action of both the vascular and nervous systems in nor- mal menstruation, and vicarious menstruation is but a perversion of physiology. The part played by congenital weakness and abnormal structure will be considered under the caption of— 3. Becquerel's and Scanzoni's Theory.-It has been observed that the seat of hemorrhage is frequently located in tissues diseased or congenitally weak. Scanzoni especially emphasizes the importance of abnormal structure of the vessels supplying the organ from which the flux proceeds. Depaul and Guéinot 298 A TEXT-BOOK OF GYNECOLOGY. (quoted by Barnes) remark "that the blood-flux usually takes place in regions or tissues deprived of their natural tegu- ment, that is, from wounds, ulcers, rupture of varicose veins, etc." This has been my observation in several cases, though there are many on record in which no such disease was present. It must not be forgotten that the diseased tissues may be the consequence rather than the cause of the ectopic discharge. If it be true that increased intra-vascular pressure plays such a prominent rôle in both normal and vicarious menstruation, it seems not illogical to presume that the escape of blood is most liable to occur at the point of least resistance. The flow gener- ally continues to recur from the seat of election, and it may take place from more than one point simultaneously. None of the several factors, then, upon which the foregoing theories-plethoric, neurotic, and local depravity of tissue-are based can be ignored in studying the etiology of vicarious men- struation. Some one element may be sufficiently conspicuous in a given case to overshadow the other two; but a more care- ful analysis will, in most instances at least, show a blending of two or more of them, each of which plays a more or less impor- tant rôle. The conclusions given by Barnes are as follows:- I. "That, as menstruation is a physiological necessity, so when the function cannot be performed in the ordinary way some substitute for it must be found, or mischief will ensue. 2. “Vicarious or supplementary functional action is a funda- mental law in physiology. There is nothing exceptional in vicarious menstruation. << 3. Vicarious menstruation may occur under various phases. 4. "It is conservative in intent and action, lessening or avert- ing evil." TREATMENT. The therapeutical propositions set forth by Barnes cannot be advantageously enlarged upon. They are in substance as follows:- I. The conditions which interfere with the proper discharge of the menstrual blood should be removed. 2. Since vicarious menstruation is often associated with VICARIOUS MENSTRUATION. 299 amenorrhea and dysmenorrhea the cause of these two symp- toms should be sought for and removed. Mechanical obstruction in some portion of the genital tract is a frequent cause, and such obstruction should be overcome. 3. When the neurotic element predominates the nutritive functions are usually disordered. Defective hematosis is of frequent occurrence, and the functional derangement is often marked. The depravity of nutrition may either precede or follow the nervous disorder. The indications in either event are to correct the constitutional bias. 4. If the vicarious discharge proceeds from an unhealthy sur- face an attempt should be made to heal the morbid seat. An effort should also be made to divert or attract the menstrual nisus to the uterus, by: (a) Derivative or revulsive bleeding; (6) local applications of iodin and the hot vaginal douche, electricity, etc.; and (d) the internal administration of such remedies as hamamelis, gossypium, digitalis, ergot, iodin, mercury, arsenic etc. Of the foregoing measures I would especially emphasize the importance of electricity and the internal remedy. The method of using electricity does not differ from that given in dealing with amenorrhea. Negative cauterization in conjunction with intra-uterine faradization, will, as I know from experience, do much in the way of attracting blood to the uterus. I have, too, great faith in the utility of the homeopathic remedy in setting right the perverted function. It should, therefore, be selected with care; an effort being made to find a drug whose action is sufficiently profound to reach the constitutional derangements, even though the word 'vicarious' does not appear in its recorded pathogenesy. Therapeutics. Pulsatilla.—Particularly suitable to mild, tearful, yielding dis- positions; pale face; difficulty in breathing after slight emo- tions; morning sickness with bad taste in the mouth; no appetite; vicarious hemorrhages in consequence of wet feet; epistaxis or hematemesis following the suppression of menses; FEELS BET- TER OUT OF DOORS. 300 A TEXT-BOOK OF GYNECOLOGY. • Bryonia.-Stitch-like pains in the lower abdomen aggravated by the slightest motion, with tendency of blood to head; membran- ous dysmenorrhea; frequent nosebleed when menses are sup- pressed; in women accustomed to too early and too profuse menstruation. Ferrum.-ANEMIC WOMEN SUBJECT TO FIERY RED FLUSHING OF THE FACE; menses appear with physical languor and mental depression, unfitting her for work; hysterical symptoms after menses. Hamamelis.-Vicarious hemorrhages from nose, mouth, stomach, or rectum, the blood being dark or venous in character; VARICOSE VEINS OF LOWER EXTREMITIES. Lachesis.-Evidences of blood degeneration; flashes of heat, especially at the climacteric; coldness of feet; palpitation of heart with feeling of constriction about the heart as if tightly held in cords; oppression of the chest with dyspnea on wakening; menses scanty but regular; desire for fresh air. Digitalis. Dr. W. H. Hoyt reports a case cured by digitalis characterized by the following symptoms: Pain in and about the chest and sometimes epistaxis before the menses, followed by choking spasmodic cough at night and expectoration of a solid bloody mass with immediate relief. This mucus was very diffi- cult to detach and presented a rusty black, clot-like appearance. (Southwick.) Kali carb.-Congestion of the brain and chest; hot flashes; burning pain in region of hips; intermitting pulse; STITCHES IN CHEST; heavy aching sensation in small of back during menses; menses acrid, of a bad, pungent odor and excoriating; backache and sticking pains in abdomen. Ipecacuanha.—Menses too early and too profuse, blood bright red; great weakness after menses; blue rings around eyes; dis- tress in umbilical region; CONSTANT NAUSEA AND FAINTING. Sanguinaria.-Scanty menstrual discharge with headache from occiput to forehead as if the head would burst; eyes pressed out; face red and hot. Sabadilla.-The menses are suppressed immediately upon their appearance, when they appear again sooner or later and are again suppressed. (Guernsey.) VICARIOUS MENSTRUATION. 301 Sulphur.-Menses too early, too profuse and of too short duration; during menses, headache, rush of blood to head, nose- bleed; burning in the vagina with troublesome itching of the genitals due to papillary eruption. Trillium.-Hemorrhage from the uterus with sensation as though the hips and back were being pulled to pieces; better from a tight bandage. (Cowperthwaite.) Hematuria; profuse nosebleed; bleeding from gums; hematemesis. (v. Therapeutics of dysmenorrhea, amenorrhea and uterine hemorrhage). Illustrative Cases. CASE XLV. Dropsy and Hematuria Attending Pregnancy.-In this case preg- nancy was attended by dropsy and hematuria. A young woman four to five months pregnant for the first time, came to the London Hospital, having had dropsy for some weeks; it was general; the labia majora were much distended. There was hydremia and she complained of palpitation. She passed blood in the urine.-Barnes. CASE XLVI.-Vicarious Hemorrhages from Stomach, Eyes and Nose.-M. A., æt. 30, single. A stout, strong woman, admitted complaining of distressing soreness of the stomach and pain in the left shoulder, extending down the arm, which was rigidly flexed; the least attempt to move it caused great pain. After being ill a month she vomited a large quantity of blood. She was carried to bed fainting-vomiting of blood recurred every month. The menstrual discharge which occurred at the same time, was regular both as to time and quantity. She afterwards bled from the eyes and from the nose. She had copious lachrymation, and a serous discharge from the ear and profuse perspiration. Everything bespoke aggravated hysteria.-Law. CASE XLVII.—Vicarious Hemorrhage from Strumous Scars, Eyes, Knees, Thighs, Chest, from the site of neuralgic pains and from the Stomach.-Madame X. had stru- mous ulcers when seven months old, on the fingers of the right hand. These cicatrized. At six years old she was seized with convulsive attacks two or three times a month; and later a sanguineous exudation took place from the scars of the hand. One day, under the influence of violent grief, blood came with the tears. From this time on the hematidrosis broke out indifferently on the knees, thighs, chest, and grooves of the lower eyelids. The menses appeared at eleven, when temporary improvement occurred, but soon disturbances returned. Then bleedings nearly always followed a moral emotion and complicated a nervous attack with complete loss of movement and sen- sibility. At fifteen the nervous attacks became more violent. They disappeared during her first pregnancy, and broke out again a year later, on the occasion of metrorrhagia. Some time after this I saw her for violent nervous attacks. Again, the menses being a few days in arrear, pains set in in the groins, thighs, breasts, head, hypochon- dria and epigastrium; relieved by chloroform; then three attacks of epilepsy came; then blood oozed from a patch on the scalp; next, all the neuralgic paroxysms were accompanied by blood-sweating at the seat of pain. At intervals blood escaped from the skin of the forehead; in the subpalpebral folds blood ran in drops. The ap- 302 A TEXT-BOOK OF GYNECOLOGY. pearance of the catamenia next day brought relief. I examined the exudation mi- croscopically. It consisted of the elements of true blood. Similar attacks supervening an arrest of menstruation recurred. Frequently she vomited blood. Relief followed the appearance of menstruation.-Parrot, quoted by Barnes. CASE XLVIII.-Vicarious Hemorrhage from the Leg, at the site of which an ulcer formed, which bled periodically every month.—Mrs. G., æt. 41. When about fifteen became subject to occasional sudden flushings of face, with slight confusion of ideas ; healthy. She was bled for "fullness of blood." This went on for three successive springs, when menstruation came on, and continued regularly until nearly six years ago. Menses always scanty and short. The flushings disappeared after the occurrence of menstruation. Six years later, after considerable exertion in breaking sticks, which she did with her right foot, she felt a pain in the calf. The skin became inflamed, and an ulcer formed over the outer and lower aspect of the leg. This ulcer never healed. When admitted, it was about eight inches long by six inches broad; the tissues around were slightly sunken; veins not varicose. The day after admission pretty copious hemorrhage occurred from the ulcer. This continued forty-eight hours, in spite of pressure by bandage. Fearing that this bleeding might have been caused by some injury during her journey to the hospital, I enquired about it; the patient in- formed me that since the date of the injury six years ago she had not menstruated at all; but that every month, about the time of the expected appearance, the ulcer bled for two days, that is, for the same time that the menstrual flow lasted, before its sup- pression. After the bleeding ceased the ulcer had the appearance of a callous, rather foul ulcer.-Buchanan. CASE XLIX. Vicarious Leucorrhea.-A girl aged twenty, sought relief for chlorosis. Since fourteen she has complained of languor, pain in the back, distention and pain in the abdomen, and mucous discharges from the vagina. For six years copious leucorrhea took place every month, following upon aggravation of pain in the loins, distention of the abdomen and lassitude.- Whitehead. CASE L.-Vicarious Hemorrhage from the Lower Lip.-A. P., sixteen years of age, had been an inmate of the Indiana Reformatory for Women and Girls, for some months, before requiring my professional attention. On March 10, 1876, I found her in the hospital room suffering with slight hemoptysis. To my surprise, I observed both lips to be swollen, and of a purplish hue, the swelling and the dark color being much more marked in the lower than in the upper lip-indeed, this was so dark and so much enlarged, that for the moment I thought a gangrenous inflammation was im- pending. Upon closer examination I found a little blood oozing from the inner surface of the lower lip. In four days all hemorrhage had ceased, and the lips resumed their normal size and color. The patient's history was briefly this: Born of healthy parents, but a cast-away, she had hitherto led a life most unfavorable for a healthy physical, intellectual, or moral development. She menstruated at fourteen, and the function was normal for two years, or up to the time of her admission to the Reformatory; it then ceased for six months, when it reappeared in the abnormal form I have detailed. She was VICARIOUS MENSTRUATION. 303 delicate in form and quite anemic. Iron was prescribed. A month after my first prescribing for her, there was a return of precisely the same symptoms that I have mentioned as observed on March 10th. May and June each repeated the previous history. Soon after the third recurrence of the abnormal menstruation, she made her escape from the Institution-an unfortunate escape for her own good, and for the in- terests of professional study.—Parvin. CASE LI.-Amenorrhea with Vicarious Hemorrhage. The patient is a young mulatto woman, whiter than most white women. She was married several years ago and gave birth to one child. Always been regular in her menstrual periods until two years before coming to me. At that time another colored woman stole her husband's affections from her and followed up the theft by attempting to cut her throat. She lost a good deal of blood from the wound. Her menses coming just at this time, she said her physician gave her two kinds of bitter medicine to stop the flow, saying she had lost blood enough. The "bitter medicine" proved effectual, as she had but three catamenial periods in the two years following, at which time she suffered with severe pains in the back and pelvis. About two weeks before I saw her she felt the symptoms of the approaching menses, but instead of the usual flow she bled profusely from both nipples. The mammæ were painful and tender to touch before the hemorrhage. I found the uterus in a normal condition. The patient complained of a throbbing in the temples at times. Also of a dull headache, made worse by stooping, and attended with constipated bowels. Belladonna and bryonia relieved her wholly of these ailments. I then prescribed cimicifuga in a low potency. There was every indication of the natural appearance of the menses at the next month, but at that time she went out in the rain and got her feet wet, and no flow appeared. I continued the cimicifuga and the following month she had a more natural and profuse flow than at any time since her troubles began. Dr. S. J. Millsop, The Clinique, April 15, 1890. CASE LII.- Vicarious Hemorrhage from Varicose Ulcers of the Legs.-Woman in bed for large varicose ulcers of both legs. Heard some bad news. Menstruation, which was going on, suddenly ceased, and ulcers began to exude blood, and continued to do so, despite compression, for three or four days. Following month ulcers, though much reduced in size, suddenly began to exude blood again, and menstruation did not appear. Ulcers healed up before next period, and patient was discharged.—Bedford-Fen- wick. CASE LIII.-Singular Case of Vicarious Menstruation.-A negro woman, about thirty-five years of age, of apparently good constitution, and, with the exception about to be mentioned, of general good health. She began menstruating at the age of fifteen, and continued regular in this re- spect until three years since. Eight years ago, when about twenty-seven years of age, she was attacked with a violent pain in the foot, which was succeeded by an abscess, which was lanced, but did not heal. Ulceration succeeded, which continued to move upward until the leg was involved and became the seat of its permanent loca- tion. About three years since the catamenial discharge began manifestly to decline, and so continued until it ceased altogether, when she was seized with severe shoot- ing pains, passing from the sacro-lumbar to the uterine region, and to the ovaries. At the approach of her next menstrual period she noticed a slow oozing of blood 304 A TEXT-BOOK OF GYNECOLOGY. from the ulcer on the leg (I give her own account of the matter), which continued about the usual time of that discharge and ceased. At subsequent periods the same discharge sometimes occurred, while at others, small sacks of blood were formed contiguous to the ulcer, which were obliged to be opened and the blood discharged before relief could be obtained. In June last, the ulceration of the leg had become so extensive and threatening, as to require, in the judgment of Dr. -(whose patient she then was), amputation. Since the operation, the ulcer being removed, there has been no regular monthly periodic discharge of blood, but at each monthly period, sacks, such as were above de- scribed, formed around the stump of the amputated limb, and required to be lanced for the relief of the patient. I have seen these sacks, and in fact opened them, and can entertain no doubt as to their true nature. So uniform are these singular oc- currences in their periodic character, as to have induced this woman to keep a lancet for the purpose, and thus surgically to perform the work of menstruation. It should be observed that she continues without any vaginal discharge, and that the deter- mination of blood to the stump of the amputated limb, together with the formation of these sacks of blood, occur periodically, and observe strictly the menstrual periods as to the time of their recurrence and duration.-Dr. Doring, New York Journal of Medicine, Jan., 1856. The following cases came under my own observation :— CASE LIV.-Vicarious Hemorrhage from Hemorrhoidal Tumors of the Rectum. -Mrs. B., æt. 36. Patient came to me from the northern part of the State, in July, 1886, stating that her physician had made a diagnosis of "cancer of the rectum," without, however, resorting to a local examination, although she had suffered intensely for three years. She was pale and anemic, and for the last twelve months had lost enormous quantities of blood from the rectum. Menstruation had been entirely suppressed for five months, and rectal hemorrhage, although recurring in small quantities after each stool, presented all the elements of periodicity. A series of rigid cross-questions were put to the patient, in order either to confirm or disprove her statement; the statement was incontrovertible. An examination revealed, not a carcinoma, but a mass of hemorrhoidal tumors which were greatly aggravated by opium, the patient taking the tincture in tablespoonful doses. On August 30th I ligated and removed the hem- orrhoids. I gradually withdrew the opium, prescribed nux vomica, and the patient made a good recovery. Two weeks after the operation she menstruated in a natural way, the first time in five months. She also menstruated Sept. 20th and Oct. 25th, since which time I have lost sight of the case. CASE LV.—Vicarious Hemorrhage from a Mole on the Forehead.—E. B., æt. 20. Of Irish descent, nervous temperament, but not hysterical, and a victim of spasmodic dysmenorrhea. This patient was not under my observation long enough to permit a careful study of all the symptoms. She caught cold just as the menses were due, and, as a consequence, was suffering much more than usual from dysmenorrhea. Upon reaching the bedside I found her bleeding quite profusely from a small mole, not larger than a millet-seed, located on the forehead. Several large handkerchiefs were completely stained with the discharge, of which there was not less than an The face was red, the headache intense, and the restlessness very great. Under the use of hot cloths externally over the abdomen, and a hot foot-bath, with ounce. VICARIOUS MENSTRUATION. 305 aconite internally, the natural flow was established, when the vicarious discharge ceased. She gave a history of being similarly affected a year or so before, and has had a recurrence of the ectopic discharge two or three times during the last eight years. CASE LVI.- Vicarious Epistaxis.—O. A., æt. 13. She is large for her years, well developed, the mammæ being prominent, with quite a heavy growth of hair upon the pubes. Every four weeks, for the last six months, she has had a profuse epistaxis. The attacks recur every twenty-eight or thirty days. Pulsatilla was prescribed, and in due time she became quite regular, when the epistaxis ceased. During the six months while suffering from the epistaxis she did not menstruate. 20 CHAPTER XXI. STERILITY AND IMPOTENCE. Sterility is a symptom, or, rather, the consequence, of so many different conditions and affections as to make it unnecessary in a chapter devoted especially to the subject to do little more than classify the causes, and to suggest the general principles of treatment. To make human fecundation possible, it is necessary— 1. For living spermatozoa to find their way into the female genital tract; 2. For the contact of spermatozoa or a spermatozoön in some portion of the genital tract with a healthy ovule capable of fertil- ization; and, finally, 3. For the occurrence of suitable changes within the uterus, that the impregnated ovule may not be prematurely expelled. The statistics of Matthews Duncan* show that about one mar- riage in every ten is fruitless. The various factors responsible for this may be classified as follows: 1. Causes preventing insemination— Impotence of the male; Impotence of the female; Stenosis of the vagina or ostium vaginæ. 2. Causes preventing or interfering with coitus— Atresia or stenosis of the vagina; Imperforate hymen ; Malformation of the external genital organs; Hypertrophy of the clitoris and labia; Vaginismus ; Prolapse of the ovary; Undue shortness of the vagina; Fissures and neuromata; *"Gulstonian Lectures," 1883. { 306 STERILITY AND IMPOTENCE. 307 3 Uterine and peri-uterine inflammation; Hypertrophic elongation of the cervix; Coccygodynia ; Disproportion between the size of the male and female organs. 3. Causes preventing passage of semen from vagina into uterus— Inflammatory occlusion of the cervical canal; Fibroid tumors and polypi; Uterine displacements; Conical shape of cervix; Lacerations of cervix. 4. Causes preventing passage of ovule into uterus— Fallopian stenosis; Fallopian adhesions; Absence of tubes. 5. Causes interfering with ovulation— Ovaritis and the various peri-uterine inflammatory dis- eases; Abnormal states of the blood interfering with the mat- uration of ova; Tuberculosis; Syphilis ; Gonorrhea. 6. Causes interfering with gestation- Endometritis ; Subinvolution and aerolar hyperplasia ; Tumors of the uterus; Membranous dysmenorrhea; Uterine hemorrhages. 7. Causes destroying vitality of semen- Abnormal vaginal secretion; Abnormal uterine secretion; Syphilis ; Tuberculosis. ! It will be seen by this long array of causes that sterility may be permanent or temporary, congenital or acquired, absolute or relative. 308 A TEXT-BOOK OF GYNECOLOGY. I. Causes Preventing Insemination.-The first fact to be determined when called upon to treat a case of sterility is the procreating power of the male. It is certainly most unjust to subject the wife to an examination and a long course of treat- ment, only to discover at the end of some weeks or months that the fault lies not with her, but with the husband.* By the term impotence is meant the inability to perform the sexual act. In the male, this may be due to a number of causes, either temporary or permanent. It not infrequently results from excesses and early indiscretions, but oftener from some exhaust- ing disease which has greatly depressed the system. Temporary impotence is not uncommon in the newly married, especially with men who are victims of the horde of unscrupulous quacks that infest the land. They have had impressed upon them the probabilities of impotence, and enter into marital relations with fear and trembling. The mind plays no insignificant part in the sexual act, and if the first attempt is not successful, as it frequently is not, an impotence more or less permanent is de- veloped which is purely mental. Dr. Hammond† has placed on record several cases of this nature. To all appearances the sexual act may be completed in a most natural way, yet no semen is ejected; or, the semen ejected may not contain healthy spermatozoa, hence the sterility. In order to determine the presence or absence of spermatozoa, an examination should be made soon after it is ejected by plac- ing a drop of the fluid under the lens of a good microscope. The spermatozoa consist of a large number of ciliated cells held in suspension by the thick, watery portion of the semen. These cells, if normal, should be seen to move about in every direction under the field of the microscope. Impotence in the female may be due to absence of sexual de- sire, to physical conditions preventing the entrance of the male * De Sinety estimates that in unproductive marriages the husbands are at fault in fifty per cent. of all cases. Treu's (La Semaine Médicale, Aug., 1889) estimate is thirty-six per cent. Fuerbringer (Deutsche Medicinische Wochenschrift, 1888) like- wise believes that barrenness is due to some defect in the virile powers of the male oftener than is supposed. + "Sexual Impotence in the Male and Female,” 1887. STERILITY AND IMPOTENCE. 309 organ into the vagina, or to inability to experience the sexual orgasm. A few words only in regard to the first and last of these causes. Frigidity on the part of the woman may be the cause of impotence in the male. That is to say, a man may not, be- cause of lack of proper response or encouragement, have his virile powers sufficiently stimulated to complete the act. In- stances of this kind are, however, rare, though the sexual appetite is very much below the normal in many women. The causes for this have been classified by Hammond as follows:* Absence, or arrest of development of the clitoris ; Extreme smallness of the clitoris ; Original absence of sexual desire. I think there is no question that in the majority of women the sexual orgasm is largely centered in the clitoris. This is not, however, true in all cases, for in many the seat of sexual pleasure lies either in the vagina, the vulva, the uterus, or equally in all of these organs. In Some women do not seem to realize they have a clitoris. instances of the kind proper instruction regarding the function of this organ during the sexual act will put matters right and the orgasm will be experienced. I have more than once found the clitoris, in women devoid of sexual desire, bound down by adhesions; after liberating the glans, sexual intercourse was perfectly normal. It is easy enough to comprehend that these various anatomical defects may give rise to impotence. There yet remains a goodly number of women in whom no such defects and, indeed, no abnormal condition of any kind can be found. Sexual inter course is not painful; the patient may possess most affectionate qualities; the act itself is not repugnant, yet she experiences not the slightest degree of pleasure, even though she makes every effort to do so. There is, in the language of Hammond, “an original absence of sexual desire." It is probable that this inherent absence is of rare occurrence. Usually there exists some reason for it—a reason which keeps a latent desire from asserting itself. Too often it is incompatibility between husband * Op. cit., p. 278. 310 A TEXT-BOOK OF GYNECOLOGY. and wife. At any rate, I have known women absolutely devoid of sexual desire while living with their first husband to possess it to a marked degree after a second marriage. This incompa- tibility is, when it exists, always a source of unhappiness, and has not, I feel confident, received from the medical profession the attention it deserves. The sexual appetite may be absent for some time after mar- riage, but gradually develops as time goes on-perhaps after the birth of one or more children. I have had related to me many instances of this kind. While it is probable that a frigid woman is not so apt to con- ceive as one possessing a normal or exaggerated sexual appetite, yet many women thus affected are very prolific. Of course, if the frigidity is such as to fail to excite the virile powers of the male, then, indeed, it may absolutely prevent, indirectly, insemi- nation. Fortunately, such instances are very rare-much more so than are instances of large families coming to women who have never experienced the sexual orgasm. Is intromission necessary for fruitful insemination ? I think that this question can be positively answered in the negative. The self-propelling power possessed by the spermatozoa enables them, even when deposited upon the external organs, to find their way upward through the vagina and into the uterus. Tes- timony bearing upon this point is sometimes necessary in cases of alleged rape. 2. Causes Preventing or Interfering with Coitus.-These several causes require no great amplification. Some of them interfere or prevent coition because of mechanical obstacles inter- posed to the entrance of the penis into the vagina; others make sexual intercourse impossible because of the pain resulting from an attempt to perform the act.* These several pathological con- ditions have elsewhere received due attention. It should not be forgotten that failure to consummate the act may be due to simple awkwardness on the part of the male, or to want of proper gentleness. The vagina is sometimes unnatur- ally small, or the male organ unusually large. This disparity in either event interferes with coition or makes it impossible. * " Dyspareunia.” STERILITY AND IMPOTENCE. 311 3. Causes Preventing the Passage of Semen from the Vagina into the Uterus.-Occlusions of the cervical canal occasionally result from sloughing or from inflammation follow- ing intra-uterine applications. A local examination will be necessary in order to determine this condition. Fibroid tumors and polypi impinging upon the cervical canal act as an obstacle to the passage of the spermatozoa. Even a very small polypus may cause sterility. Uterine displacements are likewise a frequent cause of sterility. In the case of flexures the uterine axis is so changed that the organ is bent upon itself in the form of a retort. Deformities of the cervix from any cause may prevent the entrance of the semen into the uterus. The so-called conical cervix may make it difficult for conception to occur. Lacerations of the cervix, notwithstanding the increased size of the cervical canal, are fre- quently associated with sterility. I have known many instances where women have not conceived for years, but have become pregnant soon after the cervix was repaired. The probable reason for this is that a lacerated cervix perpetuates endometri- tis, the discharge from which obstructs the cervical canal. 4. Causes Preventing Passage of the Ovule into the Uterus.-The Fallopian tubes are often obstructed by preëxist- ing disease. Indeed, it is surprising that pelvic inflammation in its severer forms ever runs its course without permanently occluding the tubes. They are frequently involved in inflamma- tion, but, unless bound down by adhesions, usually regain their normal function. If, however, the adhesions are extensive, or if pus forms in the tubes, it is next to impossible for the ovule to pass through them into the uterus. There is nothing in the physiology of menstruation more remarkable than the manner in which the ovule finds its way into the Fallopian tubes, even in normal conditions. It is probable, as suggested by Tait, that in the majority of instances, the ovule instead of finding its way into the Fallopian tubes drops into the free peritoneal cavity. If this be true, even though the parts be normal, it is certainly much more apt to be the case if there exist disease of any kind. In the vast majority of cases women with peri-uterine inflamma- tion are sterile because of the distortion and disease either of the 312 A TEXT-BOOK OF GYNECOLOGY. tubes or the ovaries. In rare instances the tubes may be con- genitally absent. 5. Causes Interfering with Ovulation.-The same diseases. involving the tubes frequently involve the ovaries as well. Ovulation will, however, sometimes continue in spite of most extensive disease. I have dug ovaries from inflammatory exudates containing Graafian follicles ready to burst, or Graafian follicles which have just ruptured. I have also removed. ovaries showing evidences of recent ovulation whose structure was almost completely degenerated. It is well known that conception may take place in women suffering from chronic inflammation of one ovary, though sterility is the usual result when both ovaries are implicated. Nevertheless, we must not too quickly sacrifice ovaries chronically inflamed. The reason why it is exceedingly hard to cure the disease is that perfect physiological rest, so long as the patient men- struates, is impossible. The nearest approach will be a cessa- tion of ovulation, the result of pregnancy, and pregnancy will sometimes follow in the most unfavorable cases. There are certain abnormal states of the blood which interfere with the maturation of the ova. Anemia, chlorosis, syphilis, tuberculosis, or any condition seriously interfering with the blood-making processes may so depress the system as to affect the function of ovulation. Gonorrhea is often responsible for sterility. I have in another place (Chapter XXVI) dwelt in detail upon this subject. The frequent involvement of the ovaries and tubes in patients suffering from gonorrhea is no longer questioned. While gonorrheal inflammation of the ovaries may not be more virulent than non-specific inflammation, yet I believe that the specific form of vaginitis is much more apt to extend to the tubes and ovaries than is the non-specific. 6. Causes Interfering with Gestation.-The list of causes includes those conditions which are inimical to the life of the ovule after it reaches the uterus. Indeed, many of the causes there enumerated are fatal to the life of the spermatozoa before they reach the ovule. Thus, endometritis, because of the abnormal secretion, interferes with the growth of the ovule. So do subinvolution and areolar hyperplasia, though there is STERILITY AND IMPOTENCE. 313 usually associated with these affections more or less endome- tritis. Tumors of the uterus either prevent that organ from growing or impinge upon the intra-uterine cavity in such a way as to cause premature expulsion of the ovum. Victims of membranous dysmenorrhea are nearly always sterile. This peculiar affection makes it almost impossible for the uterine mucous membrane to undergo those changes which are neces- sary for the reception of the impregnated ovule. Women suffering from menorrhagia and metrorrhagia are often sterile, not so much because of the excessive discharge, as because of the lesion or lesions which are responsible for the hemorrhage. 7. Causes Destroying the Vitality of the Semen.-Ex- cessive acidity of the vaginal secretion will destroy the life of spermatozoa. Cases in which this unnatural condition exists are not uncommon. Sometimes the acidity is so great as to make the discharge most excoriating. It may even excite intense irritation of the male organ after intercourse. I have more than once been able to detect this unnatural condition in making a digital examination, the finger smarting when coming in contact with the discharge. Abnormal secretion of the uterus has already been referred to. It may be due to numerous causes. While usually not acid in its reaction, yet if its pro- perties are markedly changed it will destroy the vitality of the semen. The part played by obesity in the production of sterility deserves some attention. Philbert * has recorded five instances of sterility in women unnaturally obese, all of whom became pregnant after the reduction of flesh. It is probable, as sug- gested by Fournel,† that the disease of the blood corpuscles which results in obesity affects also the uterus and ovaries, thus interfering both with the function of ovulation and the nutri- tion of the uterus. Obese women usually suffer from relaxation of the muscular fibers throughout the body, and the tissues of the uterus may likewise become implicated. At any rate, when conception does occur in cases of the kind, labor is usually * Revue Générale de Clinique et de Therapeutique, April, 1889. † Gazette des Hôpitaux, February, 1889. 314 A TEXT-BOOK OF GYNECOLOGY. most tedious. Obese women are also victims of miscarriages oftener than those of normal flesh. This is due, according to Fournel, to asphyxia of the fetus because of deficient oxidation of the blood corpuscles, the resulting accumulation of carbonic acid exciting uterine contraction and thus expelling the fetus. Duncan * states that "the average time after marriage for the birth of the first child is about one year, though not infre- quently three years elapse before the birth of the first child, and we are hardly justified in assuming that permanent stérility exists until after this time." He also considers the average interval between the birth of successive children at from eigh- teen to twenty months. And he affirms that the physiological number of children for each fertile woman closely approaches ten. Too much stress must not, however, be placed upon these deductions. Causes of various kinds, especially social, may and frequently do disturb these averages. Syphilis, tuberculosis, scrofulosis, etc., of the male are not infrequently responsible for sterility. I have already referred to the necessity of examining the semen where there is a possibil- ity of the male instead of the female being at fault. Treatment. Some of the causes of sterility which I have presented are remediable, though many are not. Most of the stenoses can be overcome by proper operative treatment. The removal of imperforate hymen is neither difficult nor danger- ous. The possibility of curing malformations of the external genital organs will depend entirely upon their nature. Hyper- trophy of the clitoris and labia is to be reduced by the scalpel. Vaginismus-often a most obstinate condition to contend with- can usually be overcome in time by combined internal and local treatment. Nothing more fortunate can befall a patient suffering from vaginismus than pregnancy, for the affection frequently dis- appears after the birth of the first child. Prolapse of the ovary is also a most obstinate affection; too often the resulting distress can only be overcome by abdominal section and removal of the displaced organ, or by attaching the fundus uteri to the anterior abdominal wall. There is no way of lengthening a short vagina; * Op. cit. STERILITY AND IMPOTENCE. 315 it is possible, however, for conception to occur even here. The patient should be instructed to lie with her hips elevated for some time after intercourse, so that the semen may be retained. Fissures and neuromata are barriers easily overcome, though they usually require surgical interference. The prognosis in uterine and peri-uterine inflammation will depend largely upon the extent of involvement of the Fallopian tubes and ovaries. Irreparable damage may be done to both, or it may be possible to restore them to their normal condition. Hypertrophic elongation of the cervix must be reduced by the scalpel. In occlusions of the cervical canal from whatever cause divulsion is to be practised.* In a goodly number of cases of uterine flexures, when the patient is otherwise healthy, concep- tion will follow this operation.† In the event of fibroid tumors or polypi the prognosis will, of course, depend upon the pos- sibility of removing the adventitious growths. Where causes exist preventing the passage of the ovule into the uterus, the prognosis is more unfavorable. It is exceedingly difficult to overcome Fallopian stenosis when the obstruction is due to inflammatory adhesions. Even here, however, measures having for their object the absorption of adhesions and the removal of inflammatory exudates may overcome the obstruc- tion. The pain resulting from extensive adhesions which involve the ovaries is, unfortunately, so great in most instances as to require salpingo-oophorectomy. Absence of the tubes is by no means an easy matter to determine. Once deter- mined, it is hardly necessary to state that further effort is useless. In the event of serious systemic disturbance much good may be accomplished by proper hygienic, dietetic, and general treat- * Outerbridge has devised an instrument, consisting of a continuous steel wire made so as to form two blades, which he introduces into the cervix six days in advance of the menstrual flow, allowing it to remain in position for from five to eight days after the period. He reports several successful cases following the introduction of this instrument. If it is used at all, I should recommend the same precaution to be observed as in the use of the intrauterine stem, keeping the patient in bed until after its removal. † v. page 269. 316 A TEXT-BOOK OF GYNECOLOGY. 1 ment. It is not an uncommon thing for women whose nutrition is seriously interfered with from any cause to conceive after being restored to a state of health. As regards tuberculosis, if this is responsible for the sterility, it is indeed most fortunate that the patient is sterile. It would, in my mind, be a most cruel thing to encourage a victim of tuberculosis to bear children, or to resort to any operation which would make conception more probable. When the blood taint is due to syphilis, anti-syphilitic treat- ment will sometimes make a sterile woman fruitful; or, if the husband is the infected party, the same treatment directed to him will often restore his virile powers. Sometimes a lacerated perineum will prevent the retention of semen within the vagina for a sufficient length of time to enable it to pass into the cervi- cal canal. The indications here are clearly to restore the peri- neum by a proper operation. So far as internal medication is concerned, it is useful just in proportion as it is useful in the several affections which have been considered as causative factors. As has been shown, sterility is a symptom of innumerable causes and diseases, and it seems to me the height of folly to prescribe for it as an affec- tion per se. I therefore deem it unnecessary to give a list of indicated remedies. In conclusion, I desire to take issue with certain recent writers, notably Reeves Jackson and Professor John Thorburn, in the statement that no operation should be performed solely for the purpose of overcoming sterility. These gentlemen infer that the desire for offspring on the part of husband or wife does not in itself warrant interference, or, at least, operative interference in any way endangering the life of the patient. They maintain that, if surgical measures are necessary for the removal of causes which in themselves demand surgical measures for the relief of the existing symptoms other than sterility, the physician is justified in operating; otherwise he is not. This would ex- clude from operative treatment that class of patients in whom nothing abnormal can be found by the ordinary methods of examination. Dysmenorrhea may even be absent, and yet divulsion of the uterine canal will sometimes be followed by STERILITY AND IMPOTENCE. 317 conception. This, under proper antiseptic precautions, is but slightly dangerous. I maintain that when a woman desires to assume the responsibilities of maternity every resource which does not too greatly endanger life or shock the sensibilities should be exhausted. At this day and age there are too many women shirking this responsibility, and the future happiness of both the husband and wife may, in no small degree, depend upon the advent of a babe into the household. The results of artificial impregnation have not been sufficiently satisfactory to warrant a description of its technique. It is to me a most revolting procedure; and it is a serious question whether or not, in the alleged successful instances where it has been practised, impregnation was not due to the dilatation inci- dent to the introduction of the syringe into the cervical canal rather than to the transmission of semen through the syringe. At any rate the percentage of successes following this procedure is so low that doubt is raised as to whether, in the instances in which pregnancy has resulted, conception would not have occurred without it. DYSPAREUNIA. This term, reintroduced by the older Barnes, is applied to that condition in which sexual intercourse is, in the female, attended with pain. It is a symptom of many of the affections enumerated as causes of sterility and of the various local diseases of the external and internal genital organs which are elsewhere dealt with. Painful sexual intercourse in women is not of uncommon Occurrence. When it exists to any marked degree its impor- tance cannot be overestimated, for the consequences are some- times most disastrous. If the attempt be persisted in, the result- ing distress will undermine the patient's health and may give rise to serious mental or nervous disease; if, on the other hand, no further effort be made to consummate the act, marital infe- licity may ensue. The subject is always a delicate one, and many times suffering is endured for years before the physician is consulted. I have more than once found dyspareunia at the bottom of some seemingly obscure nervous affection, the cause not being disclosed to me until after the patient had been under 318 A TEXT-BOOK OF GYNECOLOGY. treatment for some time. Women of nervous organization are often completely upset by even a slight degree of pain during the sexual act. When it is at all marked the sexual orgasm is not experienced, and, under these circumstances, ungratified sexual excitement is injurious. When a lesion easily detected exists, there will be little diffi- culty in finding the cause of the dyspareunia. Often, however, the seat of the mischief is more obscure, and to locate it requires no little tact. The trouble may be purely mental. Too often the girl is per- mitted to assume marital responsibilities while perfectly ignorant of them. She is not only surprised but shocked on discovering the rôle she is to play. If the husband is likewise ignorant, or if his ideas of the sexual relations have been obtained from impure sources, the first attempts at intercourse, because of awkwardness or lack of gentleness, are exceedingly painful to the female. Subsequent efforts are made with fear and dread, and in due time a peculiar nervous state is engendered in which even the thought of intercourse will result in spasm of the muscles of the pelvic floor (v. Vaginismus). The time is fast approaching when all educated mothers will realize that their full duty will not have been done until their grown-up daughters have received from them some knowledge bearing upon sexual hygiene and the sexual relations. Stenosis of the vagina, imperforate hymen, the various inflam- matory diseases of the vulva, vagina, and the pelvic organs, uterine and ovarian displacements-any or all of these several affections may not only give rise to painful sexual intercourse, but may make the act impossible. Fissures and abrasions of the vulvar outlet, so insignifi- cant at times as to make them difficult to detect, may be respon- sible for the pain. These lesions usually follow a successful attempt at intercourse. By exposing the parts to a good light slight rents or abrasions of the mucous membrane will be seen. If not extensive, they can ordinarily be healed by the patient liv- ing for a time absque marito and applying to the parts lint soaked in calendula and smeared with iodoform; or sprinkling the dis- eased surface with iodoform and then painting it over with STERILITY AND IMPOTENCE. 319 oleaginous collodion. The collodion acts as a protective and is most useful. In the case of fissure, if this treatment fails, an in- cision should be made through it, as in dealing with fissure of the rectum. A prolapsed ovary is nearly always tender, and when the penis comes in contact with it the distress is usually very great. An examination, per rectum or vaginam, will determine the cause of the dyspareunia. But a prolapsed ovary may give rise to pain and spasm at the ostium vaginæ in a purely reflex way; it is important to bear this fact in mind when looking for the cause of vaginismus when no visible lesion is found to explain the hyperesthesia of the vaginal outlet. Neuromata and carunculæ, located at the hymeneal base or the urethral orifice, are often exquisitely sensitive. In size they vary from a pin head to a hazel-nut. The smaller ones may be. difficult to detect. In order to cure these growths thorough eradication is necessary. The cause is occasionally located some distance from the vagina and genital tract. Rectal lesions, fissures, hemorrhoids, etc., may give rise to dyspareunia. Coccygodynia is another cause which will remain undetermined if the examination is confined to the genital organs. When a woman presents herself suffering from this distress- ing symptom, every effort should be made to determine and remove the lesion responsible for the difficulty. Intercourse should be forbidden while the patient is undergoing treatment, and it is usually wise to separate her temporarily from her hus- band. A little judicious advice given to the husband will often result in much good. CHAPTER XXII. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. General Considerations.-The importance of certain dis- eases affecting the external organs of generation is greater than is imagined. I refer especially to that class of affections which, though exceedingly distressing and painful, give rise to but little deformity. Of course those diseases which result in deformity, like cancer, tumors, elephantiasis, etc., compel atten- tion. The lesser affections, on the other hand, frequently give rise to the most excruciating suffering, and because the patient cannot detect the actual evidences of disease, or perhaps because of the consciousness that an ocular inspection on the part of the physician will be necessary, she suffers indefinitely before seeking medical aid. It is impossible to exaggerate the evil consequences of a long-continued pruritus vulvæ, a frequent symptom of the various affections to be dealt with in this chapter, especially in a girl or woman with a highly wrought nervous system. Sexual excitement results in many instances, and onanism in the female has, I believe, its usual origin in some pathological lesion of the vulva setting up irritation and itching. Then, too, there is a peculiar tendency to chronicity with many of these diseases. In spite of the most carefully selected internal remedy and the most energetic external applications, they often run a protracted course. This obstinacy is due in many instances to the long-continued duration of the symptoms before the physician is consulted, for, owing to the reasons already given, the average woman shrinks from the necessary examina- tion, which is infinitely more embarrassing to her than is simple digital or specular exploration. Unless there is a marked degree of deformity, or unless the patient is able accurately to locate the diseased area, the dorsal 320 DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 321 position is necessary for a satisfactory examination. By sepa- rating the labia with the fingers of the left hand, and by the aid of good side or reflected light, the disease, whatever its nature, can usually be detected. A more careful exploration is, how- ever, sometimes required in order to discover minutely hyperes- thetic points, and for this purpose a delicate silver probe, supple- mented by a good magnifying glass, should be used. DEFORMITIES OF THE VULVA. Under this head are included hypertrophy and atrophy of the labia majora and of the nymphe, and hypertrophy and atrophy of the clitoris. Deformities resulting from injuries to the perineum are treated of in the chapter devoted to that subject. Hypertrophy of the Labia Majora and of the Nymphæ may result from hyperplasia following inflammation, from mastur- bation, elephantiasis or syphilis. When limited to the labia majora it may be great enough to cause them to reach the anus, hang- ing in folds. The increase in size is rarely so great as this, though the slighter and more moderate degrees of hypertrophy are of frequent occurrence. Hypertrophy of the nymphæ is oftener observed, and not infrequently they hang below the labia majora. It is more prevalent among certain races, and is described by the older authors as the "Hottentot apron," be- cause of its supposed greater frequency in that people. There is often a lack of symmetry of the two sides. (v. Fig. 62.) Winckel records two cases, in one of which the nymphæ measured 4.6 inches and in the other 3.7 inches in length.* The same author maintains that nineteen per cent. of pregnant women have one of the nymphæ more developed than the other.† Atrophy of the Labia Majora and of the Nymphæ may be *" Diseases of Women," p. 31. +"Hypertrophied nymphæ may cause great inconvenience; it is, therefore, interest- ing to note that H. Carrard has very recently been able to show that the cause is an increase of their nerve-fibers, in the form of Meissner's tactile bodies, also in the form of club-shaped terminations and peculiar tactile bodies having an aggregation of adenoid tissue."- Winckel. · 21 322 A TEXT-BOOK OF GYNECOLOGY. either physiological or pathological. Senile atrophy of the organs takes place after the climacteric and as old age approaches, concomitantly with similar changes of the internal organs. Im- perfect development or congenital absence may characterize the external as well as the internal organs. FIG: 61. According to Hyrtl the clitoris is physiologically larger in the tropics than in colder countries. It is probable that the same causes giving rise to hypertrophy of the labia and nymphæ will give rise, if con- tinued, to hypertrophy of the clitoris, though Winckel maintains that it does not occur as a result of mastur- bation. The size of the organ varies greatly within normal limits in different subjects-from a mere tuber- cle in the anterior commissure to an erectile, miniature penis. The degree of hypertrophy is also very variable when it occurs. Frequently the en- largement is congenital, though as- suming new proportions at and fol- lowing puberty. Tait has recorded a case in which the clitoris was as large as an infantile penis.* Parent-Duch- atelet found in examining 6000 prosti- tutes, three cases of hypertrophy in which the clitoris was the size of the ordinary male organ. (Fig. 61.) Atrophy of the Clitoris, other than senile, results oftener from ad- hesions of the organ than from any other cause. I am fully satisfied that this is a condition calling for the most care- ful attention. By referring to Fig. 1, the location of the clitoris and the manner in which the nymphæ form a prepuce will be seen. This prepuce may become adherent, attaching itself to, HYPERTROPHY OF CLITORIS. A lobulated tumor was formed, apparently by enlargement of the prepuce of the clitoris. (Museum R. C. S. Photographed by the Author.) This *" Diseases of Women and Abdominal Surgery." DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 323 and binding down the entire clitoris, exactly as the foreskin in the male becomes adhered to the glans penis in phimosis. That the results are equally pernicious I am fully convinced. The peripheral nervous apparatus of the female sexual organs reaches its highest development in the clitoris, and, consequently, the sexual erethism is inaugurated in at least the majority of FIG. 62. HYPERTROPHY OF EXTERNAL ORGANS OF GENERATION. The two lateral portions are probably the labia, each of which is six inches in length and two or three inches in width. (Museum R. C. S. Photographed by the Author.) instances, by normal or abnormal excitation of this region. I say in the majority of instances, because the chief center] of sexual erethism occasionally resides in other portions of the genital tract-the uterus, vagina, and, probably, in the ovaries. Where adhesions exist the clitoris becomes almost obliterated by the overlapping prepuce, which forms the apex of the vesti- bule. Sometimes the head of the glans will slightly project, 324 A TEXT-BOOK OF GYNECOLOGY. and underneath the superficial adhesions a small quantity of hardened secretion is seen. This condition is in the larger per cent. of cases congenital, and when the nervous system in young girls is unnaturally perturbed, with evident irritation of the external genitalia, it is my practice to examine carefully for an adherent clitoris. That this condition may become in later life a source either of irritation or want of irritation, there can be no doubt. The accumulated secretions excite an itching which not infrequently ends in onanism; or in due time the unnatural condition of the parts results in a permanent atrophy with diminished or entire loss of sensation which, in the married state, makes a complete sexual orgasm impossible. In either instance the remote effects upon the mind, and the nervous system in general, are most pernicious. It is always well, therefore, in performing any opera- tion upon the female genital organs to examine the clitoris, and, if necessary, liberate the adhesions before the patient is removed from the table. The treatment of the various conditions resulting in deformity of the vulva is both medicinal and surgical. Palliative applica- tions, when chafing or itching is prominent, are most soothing and useful. Frequent bathing followed by washes of calendula, lead-water, carbolic and boracic acid solutions will often bring to the patient temporary relief. Any one of the several appli- cations and remedies recommended for pruritus vulvæ may be used when the itching is troublesome. Hypertrophy of the labia majora and nymphæ rarely call for surgical interference, though, if large enough to interfere with coition or locomotion, the knife may be indicated. The same statement holds good as regards hypertrophy of the clitoris. Clitoridectomy, recommended by Baker Brown in 1866, is no longer a justifiable operation for the relief simply of nymphomania or masturbation.* When the organ becomes sufficiently hyper- *“ This is a dark page in the history of our progress, and the operation (clitoridec- tomy), has not yet been abandoned. A short time ago I examined a young girl whose clitoris had been partially removed, and the cicatrix afterward cauterized, because the irritation had returned. What was the result? What was the result? The irritation is more severe than DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 325 trophied to cause serious deformity it should then be removed, for the purpose of reducing its size. Experience has demonstrated that it is hardly possible to break up vicious habits by clitori- dectomy, even though the most radical measures are practised for the purpose of destroying every vestige of the organ. When the operation is done for excessive hypertrophy it is best done by the galvano-cautery loop, or the Paquelin. Hemor- rhage is in most instances controlled by these methods, but if the parts seem unduly vascular deep transfixion pins and the elastic ligature may be used, after which the knife instead of the cautery can be safely applied. If the cautery is not used deep sutures should be inserted and tied before the pins and ligature are removed. The detachment of an adherent clitoris is easily accomplished, though, owing to the exquisite sensitiveness of the parts, an anesthetic is usually necessary. I have several times, in adults, done the operation after applying a 20 per cent. solution of cocain, but even then a good deal of suffering is caused. With children an anesthetic should always be used. With the patient in the dorsal posture, the labia are separated by an assistant or with the unengaged hand. The clitoris is then carefully dis- sected out by the application of a blunt instrument (the point of an ordinary director) care being taken not to lacerate the organ. After it is thoroughly liberated, the parts should be washed in a weak solution of bichlorid, smeared with carbolized vaselin, and protected with iodoform gauze. Subsequent dressings twice a day should be made, the parts being separated with gauze in such a way as to prevent their readherence. ERUPTIONS. The most frequent forms of eruptions occurring about the vulva are eczema, lichen, acne, and furuncles. The pathology of Eczema does not differ materially from eczema attacking other parts of the body. Loss of hair, with thickening of the skin ever, and manifests itself even when the patient looks at naked figures in galleries, etc. West has protested against the operation for masturbation, and at this time the majority of gynecologists are firmly convinced that it is quite as useless in epilepsy, hysteria, or masturbation."— Winckel. 326 A TEXT-BOOK OF GYNECOLOGY. and mucous membrane, result in due time. The disease usually begins on the outer surface of the labia majora, involving sooner or later the vulvar mucous membrane and the skin of the thighs and abdomen. Pruritus is the chief symptom, and is often most distressing. The connection of eczema vulva with diabetes mel- litus is of such frequent occurrence as to call for a careful exam- ination of the urine, especially in elderly women, in all instances where the eruption does not yield to ordinary treatment. The irritating character of the urine is not the sole factor in exciting the eruption, for eczema in other parts of the body is a well- known complication of diabetes. The constitutional and local treatment of this form of eruption does not differ from that of eczema in other parts of the body. It is, of course, essentially constitutional if diabetes is at the bot- tom of the difficulty. Chronic eczema is always an obstinate disease, and exacerbations are of frequent occurrence. Cleanli- ness is a sine quâ non, and yet the parts must be washed with the utmost gentleness, the soap used being of the blandest kind. 'Medicinal applications will do but little good until the super- ficial crust is softened and removed. As a preparatory measure, therefore, and for the purpose of softening the tissues, a flaxseed poultice is most useful and soothing. The number of applications recommended for eczema is legion, and I will give but few, referring the reader to special works for a more extended list. Applications of lime-water will often con- trol the intense itching. Of the ointments the various prepara- tions of zinc stand at the head. Thornburn* recommends the following: Zinci oleat., 5j, ad vaselin alb., 3ij; dilute hydro- cyanic acid (mv−x ad 3j); chloral (3ss-3j ad 3j glycerinæ); the glycerole of acetate of lead (grs. x-xx ad 3j); the unguentum acid chrysophanic (3ss ad 3j); the glyceroles of tar, boracic acid, carbolic acid, and salicylic acid. The itching may be so intense as to call for the more powerful applications (nitrate of silver, 3j ad 3j; strong carbolic acid; caustic potash, 5ss ad 3j; or even the solid nitrate of silver). As in all forms of skin disease, the internal remedy should be * "A Practical Treatise on the Diseases of Women," page 39. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 327 selected with much care. If a cure can be accomplished with- out the aid of external measures, other than those used for the purpose of cleanliness, so much the better. I am compelled to confess, however, that in my own practice eczema vulvæ has given me much trouble, and in the chronic form I have been unable to dispense with outward medicaments. Lichen is usually confined to the pubes. The papules vary greatly as regards numbers, and present the characteristic thickened and slightly indurated bases. The treatment consists of the indicated internal remedy and the application of some powder (starch and boracic acid), for the purpose of keeping the cutaneous surface perfectly dry. Furuncles sometimes occur in troublesome succession on or about the vulva. They may possess at their onset all the char- acteristics of simple acne, becoming inflammatory in due time. When large enough to cause suffering they should be poulticed, and opened as soon as suppuration is evident. Prurigo, Elephantiasis, Erythema, Syphilides, and Ery- sipelas are forms of eruptive disease attacking the vulva with greater or less frequency. Their clinical manifestations do not, however, differ essentially from those present when the several affections are located in other parts of the body. VULVITIS. Four types of vulvitis may attack the vulva-simple, purulent, follicular, and gangrenous. Simple Vulvitis is the form most frequently met with, and occurs oftener in blondes than brunettes; for some reason the secretions of the former decompose more readily than the secre- tions of brunettes. The inflammation may result from irritating discharges, from pediculi, or from pruritus. The prominent sub- jective symptom is itching, and the act of scratching greatly intensifies the disease. Ocular inspection will reveal a red and more or less eroded surface, sometimes involving the anus and nates. The treatment must be directed to the removal of the original causes. If due to irritating discharges from the uterus or vagina these should be looked after. A tampon saturated in a 328 A TEXT-BOOK OF GYNECOLOGY. boroglycerid solution will catch the discharges and prevent their coming in contact with the inflamed surfaces. This expe- dient will not only give temporary relief, but will serve as a means of diagnosis. If it is not expedient to treat the primary cause—vaginitis, cervicitis, endometritis, etc.,—the parts may be protected by smearing over them carbolized vaselin or sprink- ling them with fuller's earth, or boracic acid and starch (3j-3j). The urine should be examined for sugar. Pediculi are to be destroyed with ungt. hydrargyri, or by a bichlorid solution (grs. iij-3j). The solution of bichlorid is much cleaner and is usually efficacious. After the cause is removed the symptoms of inflammation usually subside. Applications of hydrastis or calendula may be advantageously made, supplemented, if neces- sary, by such internal remedies as sulphur, cantharis, graphites, and sepia. The causes of Purulent Vulvitis are: gonorrhea, immoderate coitus, onanism, traumatism, and uncleanliness. Simple vulvitis may become purulent if the cause continues operative long enough. The symptoms are characteristic of localized inflam- mation, attacking muco-cutaneous surfaces-slight constitutional disturbances, with first dryness and redness of the parts, which soon become bathed with a purulent discharge. The discharge frequently excites excoriation and itching. The neighboring organs are often implicated-urethritis, vaginitis and cystitis becoming complications. It is said that the urethra is oftener involved in specific vulvitis than in non-specific. However this may be, the only absolute way of differentiating between the two forms of inflammation is by the aid of the microscope. It is probable that specific pus is the more infectious, but urethritis in the male may follow contact with the non-specific virus. Treatment. The recumbent posture, cleanliness, frequent ablutions and warm fomentations are all important. I know of nothing more soothing than a stream of warm water thrown against the parts by the aid of a douche can. Calendula (1-10) is a most useful application. A dossil of lint saturated in a calendula solution should separate the opposing surfaces of the labia after the parts have been thoroughly cleaned. Other DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 329. sedative lotions and applications are: glycer. boracis žij, liq. morphiæ acet. 3j, aq. rosæ 3v (Edis); Camphor 3ss., spir. vin. rect. q. s., bismuthi carbonat. 3ss., pulv. amyli Zij (Edis); liq. plumbi. subacet. 3j, tinct. opii 3j, aq. Oj. After the sub- sidence of the acute symptoms arsenium and mercurious cor. are the remedies oftener indicated. In Follicular Vulvitis the mucous and sebaceous glands are involved, either separately or conjointly, to such an extent as to warrant the designation given. The causes are the same as in the purulent form, except that it occurs often as a complication of early pregnancy. The subjective symptoms, too, are much the same as those of purulent vulvitis, though the pruritus is usually of greater intensity. The physical signs depend upon the glands chiefly involved. If the sebaceous, the surface of the labia, extending as far as their junction anteriorly, will be studded with small rounded papillæ; if the mucous, small, red, elevated spots are seen upon the mucous membrane of the vulva, which are very vascular and exceedingly tender. The secretion is of an offensive odor and may be great enough to conceal the prominent follicles. Follicular vulvitis runs an exceedingly obstinate course, and the prognosis should be guarded. If it occurs as a complica- tion of pregnancy it may continue throughout the entire period. Abortions have resulted from the intensity of the pruritus. Vaginismus sometimes occurs in the non-pregnant, because of its protracted course. The virus is even more virulent than that of purulent vulvitis. The treatment does not differ essentially from that given in uncomplicated purulent inflammation, except that it may have to be more energetic. When the follicles are distended with pus they should be freely opened and their bases destroyed and washed with a weak bichlorid solution. This is to be followed by a moist carbolized dressing (two per cent.) as recommended by Thomas. When the course run is more chronic the inflamed points may be treated with a nitrate of silver stick or impure carbolic acid. Gangrenous Vulvitis is of rare occurrence in adults, except as an epidemic affection in connection with some types of puer- 330 A TEXT-BOOK OF GYNECOLOGY. peral fever. It has been met with as a complication of the zymotic diseases in cachectic children. In either case it is an indication of great depreciation of the vital forces and is often fatal. The gangrenous invasion begins as a grayish, reddish or black- ish vesicle, or patch, which ends in ulceration, induration and mortification (Velpeau). The treatment consists of sustaining measures and those calculated to destroy the diseased area. The first implies the judicious use of stimulants and the most nourishing and concen- trated food; the second, the destruction of the gangrenous area by the actual cautery or nitric acid. Disinfecting poultices, both before and after the application of the cautery or caustic, are to be used. The internal remedy should be directed toward the constitutional affection. Therapeutics of Vulvitis. Aconite.-Vulva dry, hot and sensitive; painful urging to urinate; urine scanty and scalding hot; more or less vascular excitement with restlessness. Belladonna.-Sensitiveness of vulva; burning pressure with weight and throbbing pain in the uterine region; sensation of bear- ing down. Graphites.-Thin white leucorrhea, which is very profuse; menses too late, or scanty and painful; ITCHING OF PUDENDA BEFORE MENSTRUATION; swelling of the labia; papules on puden- da, which give rise to much itching. Sepia.-Soreness of labia, perineum, and between thighs, with redness; sticking in pudenda; vulva feels enlarged; leucorrhea after micturition, with itching in vagina; discharge of blood after coition. Cantharis. Swelling and irritation of vulva, with violent itching; pruritus, with strong sexual desire; painful urination. Consult:-Arsenicum, mer. cor., sulphur, apis, hamamelis, hydrastis, lycopodium, platina, rhus tox., bromine and silicea. PHLEGMONOUS INFLAMMATION OF THE LABIA MAJORA. The labia majora are composed largely of adipose and areolar tissue, which is liable to become inflamed. The various forms DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 331 of vulvitis may involve the deeper structures and end in phleg- monous inflammation. It is oftener, however, due to direct injury. The symptoms follow, as in inflammation of similar structures elsewhere, in pathological succession. There is first congestion, succeeded by hardness and tension from effusion of liquor san- guinis. The effusion may be absorbed or suppuration may ensue. The pus is usually very offensive. Diagnosis.-The disease commences with symptoms of burn- ing heat in the affected area, followed by pruritus and exag- gerated glandular secretion, which is often both offensive and irritating. Pain of a throbbing or aching character soon super- venes, which is aggravated by walking or the upright posture. Suppuration is preceded by an indistinct chill. After the tumor forms, care must be taken not to confound it with pudendal hematocele, labial hernia, displaced ovary, or distention of the Bartholinian glands. Treatment.-An effort should be made to abort suppuration at the onset by perfect rest, cold applications, and the administra- tion of the indicated remedy (bell., hepar s., mercurius, apis). If suppuration is inevitable it should be hastened by hot applica- tions, and as soon as pus has formed the parts should be freely incised. The peculiar character of the tissue involved usually makes surgical interference necessary, for the abscess will be- come very large before spontaneous discharge occurs, and may even reach the abdominal ring through the dartoid sac. INFLAMMATION AND ABSCESS OF THE VULVO-VAGINAL GLANDS. Any of the forms of inflammation of the external genitalia already studied may extend to these glands or their ducts. Gonorrheal Vulvitis is, however, the most frequent cause. The duct is usually obliterated by the inflammatory process, when the gland becomes distended. If suppuration ensues it gives rise to more or less febrile disturbance. There is a beating, throbbing pain in the parts, which become very sensitive to contact or touch of any kind. Should suppuration not ensue there is formed a painless tumor or cyst varying in size from a 332 A TEXT-BOOK OF GYNECOLOGY. pigeon's to a hen's egg, which may remain dormant for an indefinite period. I have removed these sacs after they have existed for fifteen years. A non-purulent cyst is, however, liable to suppurate at any time. The swelling is located at the posterior portion of the labium majus at its outer border, impinging upon the opposite side and partially occluding the vaginal orifice. When both sides are involved, which is the exception, the introduction of the finger into the vagina may be difficult. When suppuration follows the inflammation the pus may partially escape through the duct, the abscess refilling and discharging indefinitely. I am not aware that any of the authorities mention that cysts of the Bartholinian glands may excite reflex phenomena. In a case coming under my observation the patient had long been a victim of severe attacks of migraine, for the relief of which she was compelled to resort to morphin and had almost contracted the opium habit. Both glands were enormously distended, and their complete removal required quite an extensive and bloody dissection. The incisions were closed by a continuous suture, except at their lower border, and the oozing was controlled by packing with iodoform gauze. It required some time for the cavities to close by granulation, but from the day of the opera- tion to the present time (six months) there has been no return of the sick-headaches. As an isolated instance of the kind it is interesting, though final conclusions should not be drawn from a single case. We know so little of the actual modus operandi of reflexes as at least to warrant us in recording isolated cases when marked results follow the removal of a possible cause. Treatment.—The same principles governing the treatment of phlegmonous inflammation apply to this condition during the period of active inflammation. After an abscess has formed, a simple incision is hardly sufficient, for measures must be taken to destroy thoroughly the secreting surface of the gland. This can be done by packing the cavity with lint soaked in the tinc- ture of iodin, but a more radical and satisfactory method is com- plete dissection of the sac. In non-purulent cysts this is my invariable practice, and I have many times done the operation by the aid of cocain anesthesia. From five to fifteen minims of DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 333 a four per cent. solution should be injected under the skin in the line of the incision, which should be parallel with the long axis of the labium. By inserting the point of the hypodermic needle midway between the two extremities of the contemplated incision it can be pushed upward and downward in the superficial areolar tissue, while the fluid is being gradually ejected in such a way as to make but one puncture necessary. After waiting five min- utes, an incision is made which exposes nearly the entire length of the sac, and which makes its removal possible without rup- ture. More cocain can be applied as the operation progresses if it becomes necessary. Arteries requiring it should be tied with fine catgut. The remaining cavity should be partially closed from above, if very large, with a continuous suture, drainage being provided for at the lower border; or it may be packed with iodoform gauze. Because of the danger of contamination from the urine I prefer to close all but the lower angle of the wound. The dressings should be changed at least once a day. In distention from closure of the duct any attempt to restore the patulousness of the latter is utterly useless, as is also any attempt to cure the cyst by simple incision. The secreting sur- face of the gland must be destroyed, or it will rapidly refill, and while this may be done by destructive agents applied to its interior, the complete dissection is, in my experience, a much more satisfactory and surgical-like procedure. Therapeutics of Phlegmonous Inflammation of the Labia Majora and Abscess of the Vulvo-Vaginal Glands. Belladonna.—Burning pressure, with weight and throbbing pain in the inflamed parts; bearing-down sensation. Apis mel.-Deep, penetrating pain in clitoris, extending into vagina, with swelling, dryness, and hardness of labia minora, which is relieved by the application of cold water; pain in vulva, associated with stinging, burning pain in ovarian region; ERYSIPE- LATOUS INFLAMMATION, WITH MUCH EDEMA. Hepar sulph.-Abscesses of the labia, which are very sensi- tive, with splinter-like pains and extremely offensive leucorrhea of carrion-like odor; useful either for preventing or promoting suppuration. 334 A TEXT-BOOK OF GYNECOLOGY. Mercurius sol.-Leucorrhea always worse at night; inflam- mation of labia, with smarting, corroding, and itching; vulvitis, especially of gonorrheal, or syphilitic origin, with rawness and excoriation of the parts. Silicea. Profuse, acrid, corrosive leucorrhea; burning in pudenda, with eruption on inner side of thigh; pudendal abscess, which does not readily heal, with thin discharge. Consult:-Sulphur, rhus tox., pulsatilla, kreosotum, lache- sis, borax, iodium. PUDENDAL HEMORRHAGE. Traumatic causes, such as kicks, falls, incisions, etc., may rup- ture both the skin and the bulbs of the vestibule, thus permit- ting alarming and even fatal hemorrhage to take place exter- nally. The accident is not a frequent one, and the treatment will depend upon the extent of the injury and the amount of hemorrhage. If the quantity of blood escaping is not great, cold applications, with pressure, may be all that is necessary. If this fails astringents, such as the saturated solution of alum, powdered tannin, or the persulphate of iron, should be applied. If it is not affected by these agents, the vagina should be plugged and the parts firmly compressed by the aid of a band- age; or the wound enlarged and the bleeding surface packed with styptic cotton. Surely no fatal hemorrhage ought to occur from a wound of the kind if proper surgical measures are attain- able. Nevertheless, there are several fatal cases of pudendal hemorrhage recorded. PUDENDAL HEMATOCELE, By this term is meant a hematic tumor formed by the rupture of the bulb of the vestibule, with an effusion of blood into the surrounding tissue. It is met with much oftener in obstetric than in gynecological practice, yet in the non-puerperal the same causes which sometimes give rise to pudendal hemorrhage by lacerating the skin may rupture the bulb alone. The largest pudendal hematocele I have ever seen was the result of falling astride a wagon wheel, the patient being very large and fleshy. Symptoms.-The tumor varies in size from that of a walnut to DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 335 a fetal head. It is sudden in origin, though its full size may be attained gradually. When it occurs as a complication of labor it is more apt to take place during or immediately after the expulsion of the child. At first the patient complains of noth- ing more than a sense of discomfort, but as the tumor increases in size pain and throbbing become prominent. Micturition may be difficult or impossible because of the pressure. Touch will reveal a tumor which, if very large, may obstruct the vaginal orifice. The parts in the larger effusions sooner or later become deeply discolored. The course and termination are very variable, depending upon the size of the tumor and, in no small degree, upon the treat- ment resorted to. If the effusion is small, it usually becomes entirely absorbed, or may remain almost indefinitely in the tis- sues as an encysted mass. Suppuration is particularly liable to follow parturition, in which event there is always great danger, because of the exaggerated size of the veins and lymphatics at this time, of septic infection. Secondary hemorrhage may ensue from rupture of the sac. In the treatment of pudendal hematocele an attempt should be made: (1) to limit the effusion by rest, cold applications, and the use of hamamelis, both externally and internally; (2) to pro- mote suppuration, if inevitable, by hot fomentations, poultices, etc., and the administration of hepar sulphur internally. The abscess should be opened as soon as the evidences of pus pre- sent themselves, and the cavity washed with a 1-3000 bichlorid solution. Occasionally a large tumor manifests no tendency either to disappear or to suppurate, and operative interference becomes imperative to relieve the patient of its presence. This consists of a longitudinal incision sufficiently long to enable the operator to turn out the clot. Hemorrhage is to be controlled by pressure, if possible; if this fails, by packing the cavity, after thoroughly washing it out with a 1-3000 bichlorid solution, with strips of gauze saturated in liq. ferri perchlor. For reasons already given, the dressings should be changed at least once every twenty-four hours in non-puerperal, and even oftener than this in puerperal cases. 336 A TEXT-BOOK OF GYNECOLOGY. • PUDENDAL HERNIA. In order to understand how any of the abdominal viscera can find their way into the pudenda it is necessary to revert to the anatomy of these parts (Fig. 3). The pudendal sac, formed by the deep layer of superficial fascia and the outer layer of triangu- lar ligament, receives at its neck the terminal fibers of the round ligaments of the uterus. The round ligaments are the analogues of the spermatic cord in the male and the ⚫labia majora cor- respond to the scrotum. Since the ligaments pass through the inguinal canals into the abdomen, it is entirely possible for a loop of intestine, a portion of the omentum, or even an ovary, to descend into the pudendal sacs, thus constituting a hernia. The causes are, as in the male, congenital weakness of the parts, blows, falls, violent muscular efforts, coughing, sneezing, etc. The symptoms do not differ essentially from those of hernia in the male. There is greater danger, however, of mistaking pudendal hernia for other conditions calling for the use of the knife—hence the importance of careful exploration in all tumors about the vulva before any cutting operation is resorted to. In all cases of obstinate vomiting in the female, with symptoms of intestinal obstruction, the pudendal, femoral, and inguinal regions should be carefully explored. I have met with one case of strangu- lation which had been overlooked by the attending physician, notwithstanding that the patient vomited almost continuously for three days. Fortunately, the strangulation was reduced by my associate, Dr. A. I. Sawyer. In another neglected case in which I was called as counsel the strangulation could not be overcome and a successful herniotomy was resorted to. When the contents of the sac consist of intestine and no strangulation exists the patient will complain of pain upon bending the body, which will direct her attention to the parts. An examination will reveal the characteristic symptoms of intestinal hernia-impulse upon coughing, resonance on percus- sion, absence of inflammatory signs or those of edema, and the possibility of diminishing the volume of the tumor by taxis. If the sac contains omentum alone there is greater difficulty in making a diagnosis, especially if it is adherent. Fortunately, a DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 337 mistake here would not be so serious, were a knife introduced, as in case of intestinal hernia; it is one, nevertheless, that ought not to occur. The ovary occasionally finds its way into the pudendal sac, either congenitally or otherwise. The tumor is very sensitive, especially at the menstrual period, and there is a peculiar sickening pain upon pressure. The treatment of pudendal hernia does not differ from the treatment of scrotal hernia in the male. The hips should be elevated by having placed under them a cushion, or by raising the foot of the bed. Taxis should be exerted in an upward direction in such a way as to carry the contents toward the abdominal ring. After reduction a properly fitted truss should be worn, so that the pad will press upon the inguinal canal close to the point of exit. If the hernia cannot be reduced by taxis, and strangulation has occurred, operative measures should be instituted at once. The technique of the operation is described in all text-books on surgery, and requires no description at this time. HYDROCELE. Hydrocele is an exceedingly rare affection in the female. The canal of Nuck is ordinarily obliterated in the adult female, which accounts for the rarity of both hernia and hydrocele in women. Excessive secretion of this serous membrane, which is a pro- longation of the peritoneum, constitutes hydrocele. The ac- cumulation may be either sacculated or free, depending upon the perviousness of the abdominal opening. If the latter is open the fluid can be forced into the abdominal cavity, as in hydrocele of the male. The symptoms of hydrocele are sometimes very obscure, and careful differentiation is important. The diagnosis must be reached by exclusion. The tumor develops gradually with entire absence of pain or constitutional disturbance. Inflam- matory symptoms are likewise absent, and the ordinary signs of hernia-resonance, cough impulse, etc.—are wanting. There may be translucency, but this is an exceedingly rare symptom. In all cases of uncertainty a fine exploring needle may be used with comparatively little danger. 22 338 A TEXT-BOOK OF GYNECOLOGY. Treatment. This is conducted upon the same principles as are observed in the treatment of hydrocele in the male. Simply drawing the fluid off through an aspirator may be all that is necessary. If this fails, the sac can be injected with a few drops of carbolic acid. If failure again results, the radical operation- cutting down and draining the cyst-may be done.* Apis should be given internally. EDEMA OF THE LABIA MAJORA AND NYMPHÆ. This condition is always symptomatic, either of general ana- sarca or of pressure upon the large vessels within the pelvis, usually the result of pregnancy. The swelling pits upon pressure, is usually symmetrical, and is tense and shining. There is but little pain unless excoriation follows, and the only inconvenience results from interference with sitting or micturition. The treatment must be directed to the constitutional or me- chanical cause responsible for the mischief. The heart, liver, and kidneys should be examined, and if the edema occurs as a complication of pregnancy, the urine should be carefully ana- lyzed. If due to simple pressure, the horizontal posture should be assumed as much as possible. Apis internally will do much good, and is the remedy oftener indicated. Should the disten- tion be great enough to interfere with parturition, superficial punctures with a needle or scalpel may be made for the purpose of liberating the fluid. NEOPLASMS OF THE VULVA. Almost any form of neoplasm may occur in this region. The most common are those resulting from venereal infection-condy- * Lammert (Munchener medicinische Wochenschrift, 1891) believes that gestation and the puerperum are the most prominent predisposing causes of hydrocele in women. The round ligaments during this time partake of the physiological hyper- trophy of the uterus, and inflammatory irritation of the canal of Nuck is easily excited by trauma or otherwise. He advises that small hydroceles be left unmolested. This author believes, as does Gottschalk (Cent. f. Gyn., 1887), that the effusion of serum is frequently the result of irritation caused by an escape of blood into the canal through rupture of a small vessel. Gottschalk cites a case of three years' duration which was mistaken for hernia and a truss worn during the entire time. Smital (Cent. f. Gyn., 1891) removed six ounces of fluid from a hydrocele coming under his observation. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 339 lomata lata and acuminata—yet fibromata, myxomata, lipomata, enchondromata, neuromata, lupus, and the various forms of malignant growths are occasionally met with. The condylomata lata are usually found on or about the perineum, in the region of the anus or on the inside of the labia majora. They result invariably from true syphilitic infec- tion. The condylomata acuminata, on the other hand, are oftener due to gonorrheal infection, or to non-specific leucorrheal dis- charge. The treatment must be governed by the cause. If due to syphilis, an anti-syphilitic régime should be observed. In simple papillomata, thuja occidentalis, externally and internally, will usually accomplish a cure without resorting to surgical measures. They are, however, effectually destroyed by clipping them off with scissors and touching their bases with strong nitric acid or the Paquelin cautery. Fibromata, myxomata, and lipomata are of rare occurrence. Polaillon reports in the Annual of the Universal Medical Sciences for 1892 an enormous fibro-myoma, the pedicle of which was formed by the hypertrophied round ligament, which was as large as the index finger. The rarity of these several forma- tions makes a more extended description unnecessary. Their greatest clinical importance lies in the fact that they may be confounded with some one of the several conditions causing an increase in the size of the vulva. By carefully observing their clinical history this can usually be avoided. Of the malignant growths epithelioma is the most common. A most interesting case of epithelioma of the external genitalia is shown in Fig. 63, which came under my observation at my clinic during the college session of 1890-91.* There were no signs of the disease three months previously to the patient's entering the hospital, at which time she was being treated for hemorrhoids. Her physician was so unfortunate as to spill the fluid with which he was injecting the tumors (probably carbolic acid), and it burned her severely. The accident was followed by inflammation and ulceration, which took on a malignant type. * North American Journal of Homeopathy, October, 1891. 340 A TEXT-BOOK OF GYNECOLOGY. I removed the diseased area as completely as possible with a Paquelin, and with the loss of no blood. The groin was thoroughly FIG. 63. EPITHELIOMA OF THE EXTERNAL GENITALIA. (Wood.) emptied and the parts healed kindly, but in three months' time she returned with a hopeless invasion of the disease. The consideration of neuromata will be deferred until the subject of vaginismus is dealt with. (v. page 341.) DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 341 TABLE SHOWIng the DiffeRENTIAL DIAGNOSIS OF PUDENDAL ABSCESS, HEMA- TOCELE, HERNIA, HYDROCELE, Cysts of the BARTHOLINIAN Glands, EdemA OF THE LABIA MAJORA AND NYMPHÆ, ANd Neoplasms OF THE VULVA. NAME. ONSET. Causes. SYMPTOMS. Abscess. Acute. Inflammation, trau- matism, gonorrhea, Pain, chilliness, fever, redness, swelling, etc. etc. Hematocele. Sudden. Hernia. Sudden or insidious. Hydrocele. Gradual. Cysts of the Gradual. Bartholi- nian glands. Edema of la- Gradual. bia majora and nym- phæ. matism. Parturition and trau- Sudden appearance of tumor, at first painless; discolora- tion; resolution or secondary symptoms of suppuration. May be congenital; lifting, straining, kicks, blows, etc. Same as hernia; effu- sion of blood into canal of Nuck. (Lammert, Gotts- chalk.) Impulse on coughing; reson ance; absence of inflammatory signs; effects of taxis; if sac contains ovary; great sensitive- ness and symptoms all aggra- vated at menstrual period. Absence of signs of hernia; translucency; evacuation by exploring needle and collapse of tumor. Any source of vulvar Absence of inflammatory symp- irritation. toms and signs of pus; ab- sence of hernial signs; loca- tion of tumor (backward); exploring needle (the fluid is much more viscid than that of hydrocele.) Systemic. Diseases of heart, liver, or kidneys. Pressure resulting from preg- nancy. Neoplasms of Always grad- Often no definite cause the vulva. ual. traceable. General.-Symptoms of con- stitutional lesion and general anasarca; symmetry of swell- ing; shining surface which pits upon pressure; absence of inflammation. The only neoplasm liable to be confounded with the condi- tions included in this table is a small non-malignant growth (fibroma). The diagnosis can usually be made by exclusion as well as by the physical char- acter of the growth. It is hard, painless, and unyielding. In all cases of doubt a fine aseptic exploring needle may be used with comparative impunity. CHAPTER XXIII. DISEASES OF THE EXTERNAL ORGANS OF GEN- ERATION (Continued). PRURITUS VULVÆ; HYPERESTHESIA OF THE VULVA. Pruritus Vulvæ.-This is a symptom, more or less promi- nent, of the various affections described in the preceding chap- ter. It rarely, if ever, occurs as an independent affection, yet its importance is such as to call for special attention. Causes.-Thomas and Mundé classify the causes as follows :* 1. Contact of an irritating discharge. Acute and chronic endometritis and vaginitis; Discharge of cancer ; Incontinence of urine; Diabetes. 2. Local inflammation. Vulvitis; Urethritis; Vaginitis; Follicular ulcers. 3. Local irritation. Eruptions of the vulva; Animal parasites; Onanism; Vegetations on the vulva; Vascular urethral caruncles; Growth of short, bristly hair on mucous face of the labia. To the foregoing should be added the following predisposing causes: * "Diseases of Women," p. 145. 342 DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 343 Pregnancy; Sedentary habits ; Depreciated general health; Neurotic diathesis. These various causes require no extended consideration. Irri- tating discharges give rise to pruritus oftener than does anything else. Those coming from the vagina and endometrium are the most irritating, especially when they are due to chronic inflam- matory trouble. Those cases of endometritis occurring and continuing after the menopause give rise to a discharge which is especially troublesome and obstinate. It must be borne in mind that a very slight discharge may be responsible for the pruritus, and this may proceed from the urethra, Skene's glands, or even from the vulvo-vaginal glands (Mann). The scantiness of the discharge may make it exceedingly difficult to discover its true sources. Attention has already been called to the importance of diabe- tes as a causative factor in vulvitis. The irritating character of diabetic urine is well known; consequently in pruritus vulvæ the urine should always be examined for sugar. Of the various forms of vulvitis the follicular-possibly because it occurs oftener in connection with pregnancy-is attended with the severest type of pruritus. All of the eruptive diseases give rise to more or less itching, as they do when occur- ring in any part of the body. As observed by Thomas, "the natural warmth of the parts, formed as it is by folds of tissue and covered by hair which is thickly interspersed with sebaceous and piliferous glands, makes them more likely to prove active in causing it." The parasites sometimes responsible for this symptom may be of the animal (pediculus pubis, acaris scabiei, oxyuris vermicularis), or of the vegetable variety (leptothrix vaginalis, oïdium albicans). It is maintained that the former varieties may act in a reflex way as well as by direct contact. The vegetable parasites are very rarely met with in this locality. Growth of short, bristly hair on the mucous face of the labia oftener results from some local disease, especially eczema, which modifies the nutrition of the parts. 344 A TEXT-BOOK OF GYNECOLOGY. Pruritus vulvæ occasionally occurs as a purely neurotic affec- tion. That is to say, itching may be present in its most intense form without any discoverable causes or lesions. This form of pruritus oftener occurs in conjunction with pregnancy, and may extend down the thighs and over the entire surface of the abdo- men. The extensive area involved cannot be due to direct inoculation through scratching, for in most instances there is an entire absence of secretion. It is essentially neurotic when manifesting itself in this form, and is much more apt to occur in women of neurotic temperament. Pathology. To whatever cause the pruritus may be due, there is exaggerated irritability of the nerves supplying the parts in- volved. This change consists, according to Webster,*" of a slowly progressing fibrosis of microscopical proportions, especially of the nerve and nerve endings of the clitoris and labia minora." This writer maintains that many of the nerve-fibers are com- pressed or destroyed by the dense, fibrous character of these changes. In harmony with these views, he practises the thorough removal of the affected part in order to cure the dis- ease. Symptoms.—The intensity of the symptoms will depend upon the nature of the cause and the temperament of the patient. The itching is aggravated by exercise and especially by the warmth of the bed. In the severer forms the patient cannot refrain from scratching, which only intensifies the distress, irritating and lacerating the parts. Leucorrhea is so commonly associated with pruritus that it is many times difficult to deter- mine whether it is the primary cause or the result of the vulvitis excited by scratching the parts. Treatment.—It is unnecessary to remind the reader that if any of the causes enumerated exist they must receive attention. If removable, very good; if not, measures must be taken to pro- tect the parts from contact with them. It is often imperative, too, temporarily to palliate the existing suffering, and for this purpose some form of local application is indispensable. The parts should be protected from irritating discharges by a * Edinburgh Medical Journal, 1891. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 345 medicated tampon placed in the vagina; or by applying to them some of the powders or unctuous substances recommended for the same purpose in the various forms of vulvitis. An effort should, of course, be made to cure the discharge by attack- ing the seat of the catarrh. Animal and vegetable parasites should be destroyed-the former, when occurring upon the pubes, by ungt. hydrargyri, or by a bichlorid wash (grs. iij−3j). Ascarides must be attacked through the rectum. The vegetable parasites are best destroyed by a solution of borax (3j-3j). If short, bristly hairs are found upon the mucous surface of the labia these should be removed with fine pincers. The general management of cases due to depreciated general health and sedentary habits naturally suggests itself to the practitioner. The curative treatment is both local and general. As regards local measures, I can but second the words of Dr. Ludlam :* “ "It would be cruel to deny our patient such palliatives as will miti- gate her sufferings without the least interfering with the cure of her complaint." Indeed, I claim more for many of the appli- cations than mere palliation, for I am convinced that they hasten the cure while at the same time they afford temporary relief. More than once patients with pruritus vulvæ have come to me from the hands of other physicians because local expedients had been denied them. It is true that in using local measures we cannot do so with any degree of precision. There are no specific indications for a given application in a given case, and in the larger proportion of instances the use of local applica- tions is purely empirical. As a result, almost countless num- bers of formulæ are given by various writers, and almost countless numbers are at times necessary before one can be found that will mitigate the terrible suffering sometimes present. When the pruritus occurs in its worst form there are few women who, if relief is not afforded, possess sufficient resolution to re- frain from going from one physician to another. I therefore follow in the footsteps of my predecessors and give to the reader several formulæ to draw from. I have simply selected those which appeal to my judgment, or with which I have had per- *" Diseases of Women," 6th edition, p. 532. 346 A TEXT-BOOK OF GYNECOLOGY. sonal experience. The properly selected internal remedy is all important and should be sought for with care and discrimina- tion. Previously to the use of any local application the parts should be thoroughly washed with pure castile soap or, better still, juniper tar soap. The diet should be non-stimulating and the clothing not too warm. Any one of the following applications may then be made as frequently as the severity of the symp- toms calls for :- R. Hydrarg. bichloridi, Tr. opii, Aquæ, • S. For external use only. (Thomas and Mundé.) R. Acidi hydrocyan. dil., Plumbi diacetatis, Olei cacao, • .. 3 ss 3j 3 viij. • S.-Apply after washing with cold water. (Thomas and Mundé.) R. Chloroformi, . Olei amygdalæ expressi, S.-Apply to the itching parts. (Goodell.) R. Acidi acetici, Glycerinæ, S.-Apply locally. (Goodell.) R. Sodii boratis, Morphiæ muriatis, Acidi hydrocyanici, dil., M. zij Dj · 3ij. M. • 3j 3j. M. 3j 3iij. M. NO NO • • z ij grs. xx 3i Aquam rosæ, ad. . S.-Apply with soft sponge. (Goodell.) R. Acid. tannici, Extra, belladon., Butyr. cacao, Div. in suppositories No. xx. S.—Insert one into the vagina night and morning. (May.) R. Chlorali, Camphoræ, · Rub these into an oil and then add Unguenti simplicis, Pulv. acidi borici, · S.-Apply with a brush. (Goodell.) 3 viij. M. · zij gr. x 3 v. M. āā . . . 3 iv 3j ziv. M. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 347 R. Aluminii nitratis, Aquæ destillatæ, . S.-Apply with soft sponge. (Gill.) R. Cocain hydrochloratis, Unguenti petrolei, S.-Apply to the itching parts. B. Potassii cyanidi, Liquoris calcis, Adipis, . S.-Apply locally. (Goodell.) • gr. vj 3j. M. grs. iv-vj 3j. M. gr. j-iij 3 iv 3 iv. M. מא מא For vaginal injections the following are recommended by Professor Thornburn.* The figures attached to each indicates the quantity to be used per ounce :— Acid carbolic, gr. x and upward. Liq. plumbi acetat., 3 ss. Acid. boracic, ad, sat. Acid hydrocyanici, dil., mx. Sulpho-carbolate of zinc, gr. x. Sulphurous acid, 3j. Dr. Skene recommends the following:† A powder composed of one grain of morphin to two grains of chalk, to be applied night and morning; equal parts of the tincture of opium, iodin, and aconite; iodoform in ether applied by means of an atomizer ; carbolic acid and iodin, equal parts. I again quote from Ludlam: "If there is a vesicular eruption with a raw surface, or the burning in the urethra and the dysuria are very marked, water or glycerin or both may be medicated with the tincture of cantharis and applied to the vulva by means of compresses. The urtica urens is appropriate to the erythematous form, with a scarlet surface of the mucous membrane, and where there is complaint of burning and stinging as from nettles. "In case of aphthous ulceration . . . . common borax and hydrastis are in excellent repute as palliatives *"A Practical Treatise on the Diseases of Women." London, 1885. + "Diseases of Women," p. 96. ‡ Op. cit. 348 A TEXT-BOOK OF GYNECOLOGY. Alexander Duke* recommends penciling the parts with menthol cones. Von Campe† records the following case :— "The patient, aged fifty-three, suffered for two and a half years from intense irritation of the vulva, perineum, and groin. Various and numberless remedies had been tried in vain-the sensitive portion of the skin and mucous membrane having been excised. A cessation of all symptoms occurred in two days following the use of the constant current, the anode being applied to the vulva and the cathode to the various other parts affected.” I used the constant current with marked success in one case of pruritus vulvæ. The patient was of the neurotic type and the itching, of long duration, was very severe. The labia were more or less thickened as the result of scratching, and there was some uterine discharge caused by a retroflexion of the uterus. This entirely ceased after the organ was straightened by the Alexander operation, and I could then discover no cause to account for the irritation. In a fit of desperation, and before I had seen any recorded instance of the use of electricity for this condition, I resorted to galvanism. The dispersing nega- tive electrode was applied to the abdomen and the positive, by means of a metal electrode, to the parts affected. A current of fifteen milliampères was as strong as the patient could tolerate. These applications were made every other day for two weeks, when the symptoms entirely disappeared. Four years have now elapsed and there has been no return of the disease. In another patient the pruritus entirely disappeared while using the stronger current (50 milliampères) for the purpose of absorbing pelvic adhesions. Direct applications were made by means of an intra-vaginal electrode. There was much thicken- ing of the nymphæ and labia, which subsided as the treatment progressed. Therapeutics. Sepia.-Severe itching of the vulva with swelling and eruption of the inner labia; painless vesicles in the outer part of the vulva; violent stitches sometimes extending as far as the umbilicus. * Annual of the Universal Medical Sciences, 1892. † Ibid. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 349 Graphites.—Itching and smarting of vulva; painful soreness between the vulva and thighs, the parts being covered with pimples, vesicles, and ulcers; menses too late, too scanty, and too pale; moist eruptions on various parts of the body. Rhus tox.-Eczema of the vulva with much burning and itching; relief from change of posture. Cantharis.-Pruritus associated with frequent desire to urinate, with burning pain on passing a few drops, or completely strangury. Mercurius.-Greenish, offensive leucorrhea, always worse at night, with smarting and burning after scratching; sensation of rawness; salivation, soreness of the gums, teeth, etc. Lycopodium.-A great deal of itching of the parts after menses; much restlessness at night. Kreosotum.-Violent itching of the labia, also of the vagina ; external genitals are swollen and excoriated from contact of acrid discharge from above; leucorrhea of a yellow color, stain- ing linen yellow, with great weakness. Sulphur.-Burning in the vagina; troublesome itching of the genitals with papillary eruptions about them; flushes of heat, faint spells, etc. Conium.-Pruritus extending into vagina; violent itching in the vulva and vagina, especially after menses; leucorrhea with weakness and paralyzed sensation in small of back before the discharge. Collinsonia. Especially during pregnancy or when associ- ated with hemorrhoids, constipation, or other rectal troubles. Arsenicum.-Vesicular or dry, scaly eruptions with a gan- grenous tendency; worse at night; better from warmth and warm applications. Consult:-Ambra, caladium, carbolic acid, petroleum, nitric acid, kali bromatum, silicea, and carbo. veg. Hyperesthesia of the Vulva.-This condition consists of an abnormal sensitiveness of the sensory nerves supplying some portion of the vulva. The affected area may be limited to the meatus urinarius, to one labium majus, or to the vesti- bule, or it may implicate the entire vulva. It possesses none of the characteristics of a true neuralgia, and seems to be due entirely to a hyperesthesia of the sensory nerves. 350 A TEXT-BOOK OF GYNECOLOGY. Frequency. The profession is indebted to Thomas* for the first description of this disease. I have never yet seen a case, and Mundé, whose experience has certainly been exceptionally great, has never met with one.† The authorities generally agree that the disease is not of frequent occurrence. I shall therefore, in this brief description, draw largely from the original article of Thomas. Causes. In many instances no cause whatever can be dis- covered. Occasionally it can be traced to irritable urethral caruncles and to chronic vulvitis. Hysteria and hypochondri- asis act as predisposing factors, and Thomas has met with it oftener at or about the menopause. Pathology. The condition is characterized by a "plus state of excitability" in the sensory nerves. There is an absence of inflammation, an absence of pruritus, and a physical examina- tion "reveals nothing except occasional spots of erythematous redness scattered here or there." The affection, in its uncom- plicated form, is one of simple hyperesthesia of the diseased nerves. Symptoms.—Dyspareunia is the one symptom which, in the vast majority of instances, leads the patient to seek medical advice. This is in most cases absolute, and any attempt at inter- course gives rise to the most excruciating suffering. In the worst cases, the slightest friction or even a current of air strik- ing the parts is sufficient to excite pain. The general health is affected out of all proportion to the local manifestations, and great mental depression not infrequently occurs. Treatment.- Judging from the experience of Thomas and others with local measures, I should be disposed, were I to meet with a case, to rely almost entirely upon symptomatic treatment. Galvanism might be of service, though I am unable to find any recorded evidence bearing upon this point. The local sedative effect of the positive pole ought to be useful. Thomas has destroyed the sensitive area with nitric acid, has dissected off all of the sensitive tissue, and yet affirms: "I have met with a num- ber of cases of marked character, and in not one was complete *" Diseases of Women," p. 145, 1880. "Diseases of Women," Thomas and Mundé, p. 151, 1891. DISEASES OF THE EXTERNAL ORGANS OF GENERATION. 35I relief given by treatment." He recommends: a change of air and surroundings; the use of general tonics, as arsenic, strych- nin, quinin, and iron; the removal of existing local lesions— vulvitis, urethral vegetations, etc.; frequent ablutions with warm water, followed by the use of local sedatives-opium, carbolic acid, chloroform, belladonna, iodoform, cocain-and that the patient live absque marito. We do not have to contend with the same urgency of symp- toms here as in pruritus vulvæ-hence temporary relief is not so important. In view of this fact, and because of the unsatisfactory results obtained by Thomas, who relied almost entirely upon local therapeutic measures, our greatest reliance should be placed upon the carefully selected remedy. Therapeutics. Platina.-PAINFUL SENSITIVENESS AND PRESSURE IN THE REGION OF MONS VENERIS, GENITAL ORGANS AND NYMPHÆ; ting- ling or titillation from genitals up into abdomen; frequent sen- sation as if menses would appear; menses too profuse and too short lasting; flow dark and clotted, preceded by spasm and much bearing down; pruritus vulvæ with anxiety and palpitation of the heart; vulva painfully sensitive during coitus. Belladonna.-PRESSURE DOWNWARD AS IF ALL OF THE CON- TENTS OF THE ABDOMEN WOULD ISSUE FROM THE VULVA; clutch- ing or clawing pains in the uterine region; parts sensitive; cannot bear least jar; great heat and dryness of vagina. Cimicifuga. Bruised feeling in vagina; sensitiveness of uterus; menorrhagia; grieved, troubled and sighing, alternating with cheerfulness; ovarian neuralgia, especially of left ovary; pain extends up and down left side with great tenderness. Gelsemium. Ovarian irritation with hyperesthesia of vulva; uterus feels as if squeezed by the hand; menses suppressed with passive congestion to the head. Ignatia.-Violent labor-like pains in uterus, followed by puru- lent corrosive leucorrhea; cramp-like pains in uterus, worse from touching the parts. Consult :-Cocculus, coffea, zincum, nux vomica, thuja, mag- nesium phos., and kali brom. v. also Therapeutics of Pruritus Vulva and Vulvitis. CHAPTER XXIV. VAGINISMUS; COCCYGODYNIA. Vaginismus.-The muscles of the pelvic floor, any or all of them, may contract spasmodically. The form of spasm under consideration is defined by Sims, who coined the word "vag- inismus," as "an excessive hyperesthesia of the hymen and vulvar outlet, associated with such involuntary spasmodic con- traction of the sphincter vaginæ muscle as to prevent coition.” Catrin and Molènes applied to the same condition the term vulvismus. Pathology.-The greatest difference of opinion prevails re- garding the pathology of vaginismus. Tait goes so far as to contend that the so-called sphincter vaginæ muscle (com- posed of the vulvi cavernosi muscles), exists only in imagi- nation, or, if it does exist it is made up of a few bundles of muscular fibers, and is, therefore, utterly incapable of acting as a constrictor of the vagina.* He admits, however, that the symptoms referred to are common enough, but does not under- take to explain what muscles are contracted in the spasm. The prevailing confusion is probably due to the fact that there are several classes of causes. The classification made by Mann † seems to me the best yet given. He divides the cases into three classes. In the first class the cause is to be found in some pathological lesion in or about the vulvar outlet; in the second, the seat of irritation causing the reflex spasm of the muscle is found to be in distant organs,-the uterus, ovaries, or rectum; while in the third class no local lesion can be found and the cause must be sought for in the nervous system. In the first class the anatomical changes usually observed are lesions of the hymen, erosions, fissures, redness, swollen *" Diseases of Women and Abdominal Surgery," p. 78, 1889. "American System of Gynecology, vol. 1, p. 511, 1887.” 352 VAGINISMUS: COCCYGODYNIA. 353 follicles and, frequently, papillary excrescences at the navicular fossa (Schroeder). Sims believed that in the majority of instances the lesion is located at the base of the hymen, oftener at the margin nearest the urethral commissure. These several lesions. may result in various ways. The trouble not infrequently dates from marriage, and it is probable that some partial obstacle to intercourse on the part of the woman (small vulvar orifice or a rigid hymen) is responsible for the difficulty. Other obstacles to sexual intercourse are, an abnormally high location of the vulva, so that the penis presses the meatus against the pubes and injures it, and a disproportion between the size of the male and female organs. At any rate, difficult or painful cohabitation, from whatever cause, may in time induce any of the enumerated lesions, which in turn give rise to reflex spasm. In the second class of cases the disease does not come on until after sexual intercourse has been frequently performed, and oftentimes the woman has given birth to one or more children. Any lesion of the more remote organs may inaugurate the reflex spasm. Such are: diseases of the rectum (hemorrhoids, fissures, parasites, etc.); ovarian inflammation or displacement; lacerations of the cervix and inflammatory diseases of the uterus. Of these several causes I consider lesions of the rectum of first importance. There is such intimate sympathy existing between all of the pelvic organs that in an obscure disease like vaginismus the rectum should always be examined. Finally, a different explanation must be given in the third class, where neither local nor remote evidences of disease are found to account for the difficulty. The victims of this form of vaginismus usually possess a nervous temperament, and are frequently hysterical. In one of the worst cases of this kind that I have ever met with the patient was nymphomaniacal. Just why the spasm should occur under the circumstances it is hard to say. The explanation offered by Sims, and accepted by most authorities, is the following: An ineffectual or painful attempt at intercourse gives rise to nervous apprehension on the part of the woman, so that subsequent approaches of the male result in nervous excitement and an involuntary contraction of the levator ani and constrictores cunni muscles. 23 354 A TEXT-BOOK OF GYNECOLOGY. The larger number of cases are undoubtedly due to the first class of causes, a tender or hyperesthetic condition of the hymen being oftener responsible for the difficulty than any- thing else. Symptoms.-The chief symptom is that of spasm of the muscles of the pelvic floor, excited especially by attempts at sexual intercourse. The spasm usually gives rise to pain, often very intense, and after several attempts at intercourse the approaches of the male result in such a degree of nervous apprehension as to make further effort impossible. If digital examination be attempted in the worst cases the spasm and pain are at once exhibited, and it becomes utterly impossible to insert the finger into the vagina. In several cases seen by me the vaginismus was not so decided as this, giving rise to hindrance, though not absolutely preventing, sexual intercourse. The finger could be passed into the vagina, but an evident spasm was brought on by indagation. I have had patients almost throw them- selves from the table immediately upon touching the parts. Barnes has seen cases where convulsions and syncope were excited by attempted intercourse, and Thomas reports a case in which washing the genitals, or even a sudden change of position, was sufficient to bring on the spasm. On the other hand, Mann has seen instances where an examination, even with the specu- lum, failed to provoke a spasm, yet the introitus vaginæ tightly closed on each attempt at intercourse. In another case observed by the last named author coitus was impossible, notwithstanding the fact that the patient could herself introduce the largest-sized Sims dilator. In all of Mann's cases there was undoubtedly a nervous basis for the vaginismus. The prognosis is usually favorable if proper treatment is resorted to; without treatment there is a tendency for the disease to continue indefinitely. Pregnancy and parturition do not always cure it, and the practice recommended by Sims of per- mitting coitus under ether narcosis is to be condemned. The purely nervous cases are the most difficult to cure. Treatment.-There is no question in my mind regarding the efficacy of the homeopathic remedy in the treatment of this condition. It is probable that in the majority of instances some VAGINISMUS: COCCYGODYNIA. 355 · surgical procedure will have to be resorted to before the cure is complete, but in the newly married it is my practice to try internal medication first. This is emphatically the thing to do where no local causes are discernible and when the nervous element stands out prominently. A little good advice should be administered with the remedy, for it is surprising how dense is the prevailing ignorance on the subject of marital relations. In the class of cases alluded to the wife should occupy a sepa- rate bed for at least a week or ten days, during which time frequent sitz baths are to be taken. If there is very great sensitiveness of the parts a suppository containing one grain of cocain should be passed into the vagina night and morning. It is a good plan to smear the parts with a ten per cent. cocain oint- ment before intercourse is again attempted, which attempt should be made with the utmost gentleness and care. If accomplished without pain the nervous terror is largely done away with, and sub- sequent attempts, which should be made at lengthened intervals, are usually successful. Failing to relieve the disease by this method, a more radical one becomes imperative. What this shall be must depend upon circumstances. As has been seen, the most frequent lesions are found at or about the seat of the hymen or its remains (carun- culæ myrtiformes). By touching the sensitive area with the finger or a fine probe the spasm and pain are at once produced. When this condition presents itself there is but one satisfactory way to proceed, and that is to remove the entire mucous membrane covering the diseased surface. This is done by bringing the patient profoundly under the influence of an anesthetic, exposing the hymeneal area with a Sims speculum, and, with a tenaculum and curved scissors, removing it in one continuous strip. Should there be any spurting arteries these are compressed or, if necessary, tied with fine catgut. The vagina is next thoroughly stretched with two Sims specula, or with a large bi-valve rectal speculum. After this is done the separated edges of the mucous membrane should be brought together with a continuous catgut suture and the op- posing walls of the vagina kept separated with iodoform gauze. Sims devised for this purpose his well-known dilator (Fig. 64) 356 A TEXT-BOOK OF GYNECOLOGY. which is to be kept in the vagina, after his cutting operation, for some days. I do not like it, for it not only gives rise to much suffering, but dams up the discharges and interferes with the healing of the wound. Subsequently, after the parts are per- fectly healed, these dilators may be advantageously used by the patient herself in order to maintain a patulous condition of the canal. Any other traces of disease at or about the vulva should be looked after, the urethral orifice being carefully inspected. If urethral vascular tumors exist they should be snipped off with scissors and their bases touched with the actual cautery. The rectum should next receive attention. My ob- servation has been that, in most cases of vaginismus, there is constipation with more or less spasm of the sphincter ani mus- FIG. 64. TIEMANN-CO-NY SIMS'S VAGINAL DILAtor. cles. It is my practice, therefore, to divulse the rectum at the same sitting, and to remove any disease of this organ that may exist. In one case previously operated upon without success by a well-known gynecologist, who limited his operation to the vagina, I succeeded in curing perfectly both the vaginismus and the constipation by simple divulsion of the vagina and the rectum. Where no local causes are found, and the case is essentially neurotic in all of its aspects, I wish to emphasize two things essential to successful treatment: First, the constitutional treat- ment is of the greatest importance, and should be carefully looked after in all of its details; secondly, when divulsion is resorted to, let it be done in the most thorough manner. In- complete divulsion is worse than useless, and I am confident that VAGINISMUS: COCCYGODYNIA. 357 failures often result from an unnecessary fear of overstretching the parts. The irritable muscle must be paralyzed, to accom- plish which a considerable degree of force is necessary. In case of disease or displacement of the organs above the vagina, due attention must be paid to them. I once had to do in my clinic with a case of vaginismus which was most obstinate, though not absolute, and which was due to an exceed- ingly excoriating discharge from the uterus. The acridity was so great as to cause excoriation of the male member after inter- course. There was a flexion of the uterus with obstruction, which kept the secretions pent up. This case was ultimately cured by divulsing the cervix, thus establishing free drainage of the uterus. Sims's operation for vaginismus is a much more bloody one than that given, and seems to me an unnecessary mutilation. It consists of a deep cut made with a scalpel through the vaginal tissues on either side, terminating at the raphe of the perineum. A third incision is extended directly backward through the peri- neal raphe, completing the lower part of a Y. The vertical incision is about an inch deep. The parts must be kept dilated with the Sims dilator until perfectly healed. Therapeutics. Belladonna.-The spasms come on suddenly and disappear with equal suddenness; a sense of heat and dryness is felt in the parts. Platina. Spasm and constriction of the vagina in nervous women with great hyperesthesia of the parts; depression of spirits, anxiety, and palpitation of the heart; nymphomania. Caulophyllum.-Excessively irritable vagina; intense and continued pain and spasm. Cocculus.-Aggravated at every menstrual period; much weakness and prostration during menses. Magnesium phos.-Vaginismus with neuralgic pains in back, which are darting, boring, and remitting in character. Ferrum phos.-Vaginismus associated with throbbing pain and congestion of the parts; symptoms made worse by motion ; dysmenorrhea, with hot, flushed face, and quick pulse. 358 A TEXT-BOOK OF GYNECOLOGY. Cimicifuga.-Intense intermitting, neuralgic-like pains, at- tended with cramps in lower limbs. Berberis.—Intense pain in vagina, with burning and soreness as if excoriated. Consult:-Causticum, conium, kreosotum, mercurius, nux vomica, and nitric acid. Coccygodynia.-This name signifies pain in the coccyx. It is one of the causes, and a very frequent one, of so-called “pain- ful sitting" (Duncan). The affection is of quite common occur- rence and calls for careful consideration. Anatomy.—The coccyx is formed by the four last rudimen- tary vertebræ of the spine. It juts sharply forward, forming an obtuse angle with the sacrum. The sacro-coccygeal articula- tions permit of a limited degree of backward movement during defecation and parturition. Through disease, or because of changes resulting from advancing years, ankylosis occasionally occurs. It serves as a point of attachment for the sphincter ani, leva- tores ani, some of the fibers of the glutei, and the ischio-coccygei muscles. The greater or lesser sacro-sciatic ligaments are also attached to it (Fig. 2). These various structures are called into play during the acts of sitting, standing, and defecation. If the bone is diseased, or its surrounding structures hyper- esthetic, these several acts reveal the condition under considera- tion. Causes.-Coccygodynia occurs either as a symptomatic or an idiopathic affection. Any of the diseases of the genital organs or of the rectum may give rise to it. When symptomatic of dis- ease of these organs all evidences of lesions of the bone itself will be wanting. The most frequent cause is traumatism- kicks, falls, horseback riding, etc.-and the injuries resulting from parturition. In a total of twenty-four cases observed by Scanzoni, nine were caused by delivery. It is more apt to occur in primiparæ somewhat advanced in years. Two cases coming under my observation were the result of falling down stairs, the buttocks striking upon the steps. While by far the larger per cent. of coccygodynias are met with in women, it is 1 VAGINISMUS: COCCYGODYNIA. 359 by no means confined to them, men and even small children oc- casionally suffering from the affection. Pathology. This, as suggested by the causes enumerated, is variable. In perhaps the majority of instances inflamma- tion and necrosis are wanting. Luxation is found in a goodly number of cases, but luxation does not always give rise to pain. In examining one hundred and eighty pelves, Hyrtl found thirty-two cases of luxation and ankylosis. This is a sur- prisingly large per cent., and far exceeds the ratio of frequency of coccygodynia. The most distressing cases that result from luxation occur when the bone is directed backward and becomes fixed. Periostitis and necrosis of the bone sometimes develop, when the local evidences of disease can be discovered. abscess may form as a result of the inflammation. condition is symptomatic of lesions of neighboring organs the pain is probably due to hyperesthesia of the tendons, or the tendons may be the seat of rheumatic disease; at least, pain in this region is sometimes associated with lumbago, and is more apt to occur in the rheumatic and neuralgic diatheses. An When the Symptoms. Any movement causing a sudden contraction of the structures attached to the coccyx will, if the bone or its surrounding structures are diseased or hyperesthetic, give rise to acute pain. It is often most intense during the act of defeca- tion, and care must be exercised in distinguishing it from pain due to rectal disease or a displaced ovary. It is aggravated by walking and by sitting. Sometimes the latter act is impossible, or the patient is compelled to rest one buttock on the edge of the chair in such a way as to protect the tender bone from pressure. If there is a history of an injury, or if the symptoms enumerated follow parturition,* coccygodynia should always be suspected. These suspicions may now be confirmed or banished by placing the patient upon her side and grasping the bone be- tween the forefinger in the rectum or the vagina and the thumb externally. If the symptoms result from coccygodynia, move- ment of the bone will excite intolerable suffering. If the bone *"I have more than once heard this joint snap, during labor, with a sound so loud as to be heard some distance from the bed.”—Goodell. 360 A TEXT-BOOK OF GYNECOLOGY. itself, or its periosteum, is involved, there is also tenderness on external pressure. The differential diagnosis will have to be reached by exclusion. Existing diseases of the rectum, vulva, vagina, or uterus which might give rise to similar symptoms should be sought for. Lesions of the rectum are not infrequently confounded with coccygodynia, and, indeed, lesions of that organ often ex- cite true coccygodynia, as has been shown. In all instances of the latter affection, whether reflex in origin or due to actual dis- ease of the bone, the pain is excited by manipulation in the manner described. Goodell maintains that the coccygeal joint is quite as liable to become hysterical as is the knee joint.* A differentiation here is sometimes exceedingly difficult. The hysterical affection is usually characterized by those erratic manifestations of pain which stamp the character of hysteria wherever found. The prognosis necessarily depends upon the cause of the dis- ease, though with proper treatment it is usually favorable. Treatment. The cause must be sought for and removed if possible. The rheumatic and neuralgic cases are best reached by internal medication. Sometimes galvanism is exceedingly useful, and I have more than once succeeded in relieving the pain by passing a twenty milliampère current through the parts. This may be done by using the negative pole direct, either in the vagina or rectum, and a large dispersing positive electrode over the coccyx and the lower surface of the sacrum. Galvanism will at least afford temporary relief in most instances where the bone is not actually diseased. If the pain persist in spite of the more conservative measures, there are two operations, one or the other of which usually proves successful. The first is the subcutaneous separation of the ligaments as proposed by Simpson. A tenotomy knife is inserted under the skin at the tip of the coccyx and carried to its base. The muscular and tendinous attachments are completely severed from the bone on either side before the knife is with- drawn. If for any reason this procedure is difficult or impossi- * "Lessons in Gynecology," p. 96. VAGINISMUS: COCCYGODYNIA. 361 ble the method of Thomas may be practised. This author makes an incision extending the entire length of the coccyx, grasps the tip of the bone, and separates the attachments with scissors. A still more radical measure is that of Nott, and is indicated if the operations of Simpson and Thomas fail to cure the disease, or if the bone is necrosed. The coccyx is laid bare, disarticulated, and removed. This is not a difficult opera- tion and can be done by any surgeon possessing a modicum of skill. The edges of the wound should be coaptated and a drainage-tube left in for several days. Because of the close proximity to the rectum it is best to use antiseptic injections until the discharge ceases. Total extirpation affords complete relief in almost every instance. Therapeutics. Magnesium phos.-Sudden, piercing pain in coccyx; sud- den, violent, concussive, tearing, stitching pain in the region as if the coccyx were bent backward. Cicuta vir.-Tearing, jerking in the os coccygis, especially during menses; painful feeling of stiffness in the muscles of the lower limbs; general prostration; bruised sensation throughout the body. Lachesis. Continual pain in sacrum and coccyx; pain in small of back, as if sprained, hindering motion; agonizing pain when rising from a chair. Belladonna.-Intense, cramp-like pain in small of back and os coccygis; relieved by standing or walking slowly. Causticum.-Dull, drawing pain in the region of coccyx; every movement of the body gives a pain in the small of the back. Graphites.-Violent itching of the coccygeal region, the parts being moist with scurfy eruption; dull drawing in the coccyx in the evening. Mercurius. Tearing pain in the coccyx; worse at night; pain in the sacrum, as if one had been lying on too hard a couch. 362 A TEXT-BOOK OF GYNECOLOGY. Kreosotum.-Drawing pain along the coccyx down to the rec- tum and vagina, where a spasmodic contractive pain is felt; better when rising from her feet. Consult:-Cimicifuga, ferrum phos., zincum, thuja, muriatic acid, rhus tox., kali carb., and ruta grav. CHAPTER XXV. CONGENITAL AND ACQUIRED MALFORMATIONS AND DISEASES OF THE VAGINA. OCCLUSIONS. The various conditions which give rise to occlusions of the vagina are:- Atresia vulvæ, Imperforate hymen, Persistent hymen, Congenital atresia vaginæ, Acquired atresia vaginæ. Symptoms.-Atresia vulvæ is usually discovered during in- fancy; the other form of occlusions are ordinarily not detected until they interfere either with the exit of the menstrual blood or the marital relations. The occlusion, whatever the cause, may be either partial or absolute. When the menstrual blood is retained the subjective symptoms are the same as have been described under the head of "Retention of the Flow."* The girl reaches an age when she should menstruate and undergoes all the physical changes of puberty. At certain regular intervals all of the phenomena of menstruation recur-except the flow. There is an exaggerated degree of suffering, and the pain is of a bearing-down character. Sooner or later the retained discharge gives rise to a tumor. A physical exploration is always necessary in order to determine the cause of the obstruction. The same symptoms occur when the obstruction is higher up in the uterus. Results of Menstrual Retention from Occlusions of the Genital Tract.-The higher the occlusion is located in the geni- tal canal the greater is the danger of rupture from distention of * v. page 233. 363 364 A TEXT-BOOK OF GYNECOLOGY. the uterus and Fallopian tubes. If the obstruction is located at the hymen, or low down in the vagina, the distensibility of the canal will enable it to expand greatly before the uterus becomes dangerously distended. It is claimed by some prominent authorities that hematosalpinx never results from a reflux of blood through the uterine ends of the tubes, even though the uterus is enormously distended. The Fallopian distention, it is maintained, is due to a vicarious discharge from the lining mem- branes of the tubes, which is excited by the obstruction. However this may be, hematosalpinx is oftener found in occlusions of the cervix than in occlusions of the vagina, and tubal rupture, with resulting peritonitis, is liable to occur at any time; or if the uterus be suddenly emptied uterine contractions are occasionally excited which may extend to the tubes and cause rupture. Again, as a consequence of the distention, wherever the tumor may be located, the uterus and Fallopian tubes are carried high up in the pelvis, and the latter often become adhered. As a result they are dragged upon after the uterus descends, and in this way rupture may occur. ATRESIA OF THE VULVA. Atresia of the vulva may be either congenital or acquired. When congenital it is usually detected soon after birth by the nurse, who, in bathing the child, observes that something is wrong. It rarely involves the urethral orifice, so that urination is not interfered with. Should the agglutination seal entirely the opposing lips of the vulva retention of the urine would, of course, result. When acquired, it is usually due to vulvitis with resulting adhesions. The firmness of the adhesion varies greatly, though it is seldom difficult to overcome The diagnosis is easily made by separating the labia, and the treatment is, ordinarily, most simple. If the agglutination extend high up, and has become firm, a dissection more or less extensive may be necessary. I have, however, never met with such a case, though I have repeatedly had to do with this form of atresia in babies and young children. In almost all instances adhesions of the clitoris are associated with the condition and should be broken up at the same time. MALFORMATIONS AND DISEASES OF THE VAGINA. 365 Any blunt instrument or probe will serve the desired purpose. This is passed between the labia in such a way as to separate them perfectly. Care should be taken to prevent re-agglutination by keeping the raw surface separated for a few days with a strip of lint smeared with carbolized vaselin. Notwithstanding the ease with which the diagnosis can be made and the obstruction overcome, I have had patients brought to me from a distance of two hundred miles because the medical attendant believed that he had to do with an extensive and a firm atresia. IMPERFORATE HYMEN. Anatomy. The hymen (Fig. 1, h) separates the external and internal organs of generation. It is supposed to be formed by the closed lower ends of Müller's ducts. In shape it is usually crescentic; the opening may be circular, cribriform, or there may be two large openings separated by a narrow strip of mem- brane. It is occasionally absent, even in virgins, and in parous women the caruncula myrtiformes are usually the only remaining evidences of the organ. The presence of the hymen is not absolute proof of virginity; nor does its absence prove that sexual intercourse has taken place. It is possible for sexual congress to occur without its rupture, and, as we have seen, it may be congenitally absent. Its rupture is fre- quently the result of other causes than sexual congress—injury, examinations, onanism, etc. From a medico-legal standpoint this fact is important, and the practitioner cannot be too cautious in presenting testimony bearing upon the question of virginity. There are many cases on record in which pregnancy occurred before the hymen was ruptured. Symptoms. In by far the larger proportion of cases the obstruction gives rise to no trouble previously to puberty. In- deed, the patient may not seek relief until marriage, for, strangely enough, the system will occasionally adapt itself to the unnatural condition; and, after a period of suffering more or less prolonged, a fair degree of health is enjoyed. Usually, how- ever, the symptoms resulting from the retained menstrual dis- charges call for immediate relief. During the molimina there is more or less fever, nausea, vomiting, headache, etc. The 366 A TEXT-BOOK OF GYNECOLOGY. pelvic pain is very great, and radiates down the thighs. The rectum and bladder are often impinged upon and their func- tions interfered with. As the case progresses, the complexion becomes sallow, the headache constant, and there may be mani- festations of septicemia and pyemia, as indicated by chills, increased temperature, etc. Sometimes vicarious bleeding takes place from the nose, lungs, rectum, or from any part of the body. Physical Examination.-Rarely do all of the foregoing symptoms occur in a given case, yet a persistence of any num- ber of them, especially if they exacerbate at more or less regular intervals, calls for a physical examination. This will reveal a tumor of greater or less size, depending upon the duration of the occlusion and the capacity of the pelvis. There is a bulging of the hymen, and the finger carried into the rectum will detect the presence of a fluid tumor crowded against it. By recto- abdominal palpation, fluctuation can at times be detected. The distention is greatest immediately after the subsidence of the molimina. There is undoubtedly more or less resorption during the intermenstrual period, and, as has already been sug- gested, if menstruation ceases because of the anomalous condi- tion, the accumulated blood may be largely resorbed. The given history, supplemented by a careful physical exploration, will usually enable the practitioner to make a correct diagnosis. Notwithstanding the fact that the operative measures neces- sary to overcome the obstruction are very simple, a guarded prog- nosis should be given. All specialists are agreed as to this. Retained menstrual blood, from whatever cause, cannot be liber- ated with impunity. The greater the quantity and the longer it has been retained the more dangerous is its withdrawal. I have previously mentioned some of the accidents to be dreaded— reflux of blood through the Fallopian tubes into the abdomen, and rupture of the tubes. A still more serious one is that of decomposition through the admission of air. Treatment.-Operators are not agreed as to the best method of removing the pent-up discharge when due to the cause under consideration. Emmet and a few followers advocate a large in- cision, rapid evacuation, and subsequent douching of the cavity • MALFORMATIONS AND DISEASES OF THE VAGINA. 367 until the water returns clear. The larger number of operators, however, prefer the more conservative method of gradual evac- uation. It is claimed by the advocates of the latter method that there is much more danger of blood poisoning and rupture of the uterus and the tubes when the fluid is rapidly withdrawn. Recent statistics bearing upon the subject tend to uphold this claim. Thus Hemenway* has collected 81 reported cases of imperforate hymen, which were operated upon with the following result: Of the 56 cases rapidly evacuated the mortality was 7, or 12.5 per cent.; whereas of the 25 cases operated upon by the gradual method but one died, a mortality of but 4 per cent. An analysis of Emmet's cases † shows that the quantity of blood evacuated in each was not great,—an average of about six ounces. This is a very different state of affairs from that represented in Fig. 65. In this representation the uterus is carried upward, its cavity and that of the vagina are greatly distended, and their absorbing surfaces much increased. Even if sepsis could be avoided in cases of this kind by the strict observance of every precaution the danger of laceration and rupture from the drag- ging upon the parts would, in rapid evacuation, be very great. Ross, ‡ in order to prevent collapse in these cases, makes a small opening into the hymen, through which he passes the douche nozzle and washes the treacly discharge entirely away. The cav- ity is kept distended with fluid until it is forced out by iodoform gauze, which is carefully packed into it. The gauze, he main- tains, is soft, unirritating, and antiseptic, affording both support and drainage. If rapid evacuation be practised in the larger accumulations this procedure appeals to my judgment. At any rate, in the light of the statistics now available, and with modern antiseptic methods, it is probable that the smaller accumulation can be rapidly evacuated with but little danger. The cavity should be washed out with a 1:5000 bichlorid solution, being careful that it is properly drained. This should be repeated often enough to prevent resorption of any of the discharge. * American Journal of Obstetrics, Nov., 1891. +"Principles and Practice of Gynecology," p. 195, 1884. Journal of the Am. Med. Association, 1891. 368 A TEXT-BOOK OF GYNECOLOGY. In the larger accumulations, on the other hand, and particu- larly if the Fallopian tubes are distended, gradual evacuation would seem to be the safer procedure. In it care must be taken to prevent the invasion of germs. A small quantity of fluid may be daily drawn off by means of an aspirator; or a small, elliptic incision may be made in the hymen in such a way as to prevent rapid egress of the fluid (Hewitt). A still safer and better method FIG. 65. C."EVY C.BOOLDANZ IMPERFORATE HYMEN WITH DISTENTION OF VAGINA AND UTERUS. is, to my mind, the following: About three feet of rubber tubing is attached to a medium-sized trocar. This is filled with a five per cent. carbolic solution, the lower end of the tube being kept immersed in the same solution. After the genitals have been thoroughly scrubbed in bichlorid the point of the trocar is passed into the hematic tumor and the accumulation permitted grad- ually to drain away. This will require some days, during which time the patient should lie quietly in bed. After the trocar is MALFORMATIONS AND DISEASES OF THE VAGINA. 369 removed the opening made by it is to be kept patulous by the insertion of a drainage tube, through which the cavity can be kept clean by frequent washings. By this method the danger from both sepsis and rupture is reduced to a minimum. Should, however, the evidences of sepsis supervene there is but one course to pursue, and that is to open the hymen freely and to remove, under a bichlorid stream, as much of the débris as can be removed. A subsequent operation is usually necessary, after any of the gradual methods, for the purpose of destroying the hymen. This may be done by entirely removing the membrane with a pair of curved scissors, and closing the wound thus made with a continuous catgut suture; or by making three or four incisions down to its base and inserting a Sims vaginal dilator, which is to be retained for several days. I much prefer the former method because it does away with all remnants of the hymen, which, if left behind, sometimes become inflamed and give rise to vaginismus. PERSISTENT HYMEN. In this condition there are one or more openings in the hymen which insure the egress of the menstrual blood. The membrane is, however, unduly tough, and prevents or interferes with the intromission of the male organ. It is usually not discovered until an attempt at coition has been made. Indeed, the first knowledge of the unnatural con- dition is often obtained by the accoucheur, who finds the hymen stretched over the advancing head. In these cases conception has occurred notwithstanding partial intromission, the semen having found its way through the hymeneal aperture or aper- tures; or the hymen, after frequent attempts at intercourse, be- comes stretched and elongated to such a degree as to permit the complete insertion of the male organ. It is a well-known fact that conception may occur through a very minute opening. If not interfered with, the membrane may be ruptured during the parturient act, but if very dense it can oppose great resist- ance, and there is danger of serious injury being done to the vaginal outlet. 24 370 A TEXT-BOOK OF GYNECOLOGY. A perfectly normal hymen may remain intact because of the inability of the male to rupture it. In time, if sexual inter- course is persisted in, the parts become tender and sore, which leads the patient to consult her medical attendant. Instances are on record in which the urethra has been greatly dilated by the introduction of the male organ, the unyielding hymen directing it into the urinary canal. The treatment, under whatever circumstances the anomaly is discovered, is very simple. The hymen is to be removed in the manner already described under the preceding head. Spon- taneous rupture should never be permitted in parturition. It is much safer to overcome the obstacle by stellate incisions made with a pair of scissors. The raw surfaces are to be kept from reuniting by a pledget of iodoform gauze. CONGENITAL AND ACQUIRED ATRESIA VAGINE. Congenital atresia of the vagina presents itself under several different forms. The Müllerian ducts may have so failed in their development as to produce no trace of the canal; or they may have created the lower part of the canal, the upper being en- tirely closed; or there may be two cul-de-sacs, one above and the other below a central partition; or the canal may be repre- sented simply by a fibrous cord. Acquired atresia likewise varies greatly in form and extent. It may result from any one of a number of causes, though pro- longed pressure of the fetal head is oftener responsible for it than anything else. However, any disease or accident giving rise to inflammation, ulceration, or sloughing may end either in atresia or stenosis. Such are: vaginitis, syphilitic ulceration, or ulceration resulting from low fevers, the application of strong medicaments, and traumatism. Symptoms. Like imperforate hymen, atresia in itself gives rise to no inconvenience, and it is only when the disorder ob- structs the menstrual discharge, or interferes with coition, that trouble is caused. When congenital, therefore, it is rarely de- tected until puberty, and often not until marriage. If the uterus and ovaries are developed, there will be retention of the men- MALFORMATIONS AND DISEASES OF THE VAGINA. 371 • strual discharge, with all of the symptoms incident to that condi- tion. On the other hand, if the development of these organs has also been arrested, the function of menstruation is held in abey- ance, and the amenorrhea is absolute. In the latter event all signs of puberty are wanting: the breasts do not develop, no hair appears upon the mons Veneris, and the figure assumes few of the characteristics of womanhood. If the atresia be acquired, and is the result of parturition, the patient, having already menstruated, will suffer from menstrual retention when ovulation is reëstablished. Physical exploration will, in most instances, enable the ex- aminer to determine the nature of the trouble. It is not, however, always so easy to determine the presence or absence of the uterus and ovaries. If all signs of the molimina are wanting, together with the usual changes of puberty, the physi- cian is reasonably safe in concluding that they are either absent or arrested in their development. The examination should be conducted as follows: Place the patient upon her back and practise recto-abdominal palpation, endeavoring to press the organs toward the finger in the rectum. Under anesthesia this is sometimes very satisfactory. Next pass a sound into the bladder, and direct its tip toward the finger in the rectum. If it come in contact with the finger, the evidence is pretty conclusive that no uterus intervenes. By carrying the point of the sound toward the lower part of the rectum the examiner can deter- mine the thickness of the structures between the bladder and that organ. This is important in determining whether or not an operation is practicable. Prognosis. There are many factors to be considered in deal- ing with the prognosis of vaginal atresia. It may be stated in a general way that the prospects of restoring the canal to its former condition, or, by surgical interference, of making a new vagina, depend upon the amount of tissue intervening between the bladder and the rectum. In the congenital cases, if there is no vestige of the canal, and if the uterus is absent, the possibilities of creating a new vagina are not encouraging. On the other hand, if the vagina is represented by a fibrinous band leading to the uterus, or if the closure is the result of accident, without 372 A TEXT-BOOK OF GYNECOLOGY. the loss of too much tissue by sloughing, the prognosis is much more favorable. Too much, however, must not be promised. I know of noth- ing more trying to either the surgeon or the patient than an attempt to create a new vagina. There are few women willing to endure the long suffering incident to such a procedure. Yet, with the coöperation of the patient, it is surprising what can be done even in the worst cases. When the operation is performed chiefly for the purpose of liberating pent-up menstrual discharge it may not be wise to attempt to create a canal of normal size. If, however, there be sufficient tissue to permit of this without endangering the rectum and bladder, it should be made. Treatment.—The question of operative interference in a given case of atresia must depend upon circumstances. The occlusion in itself, like imperforate hymen, neither endangers life nor gives rise to great inconvenience. It is only when it interferes with one or both of the functions mentioned-menstruation and coition—that we are called upon to decide as to the necessity of an operation. There is no question as to the wisdom of operative interfer- ence if the menstrual blood is retained, and there is a fair pros- pect of reaching it. On the other hand, if the patient has never shown any signs of menstruation, probably because of an absence of the uterus and ovaries, the sole object of the operation is to make sexual congress possible; here the decision must rest with the patient. I question very much the right of a woman thus afflicted to assume the responsibilities of the married state if aware of her condition previously to entering upon it. Unfor- tunately, these patients are usually ignorant of their deformity until an attempt is made to consummate the marriage, and it is their inability to consummate it that brings them to the specialist. In all instances of the kind we are justified, if it is the patient's wish, in making an attempt to create a vagina, as we are also where the atresia is acquired, providing there be a fair prospect of success. The operation, though not complicated, nevertheless requires care, perseverance, and skill. The patient should be thoroughly anesthetized and placed in the lithotomy posture, with the hips MALFORMATIONS AND DISEASES OF THE VAGINA. 373 well over the edge of the table. The anatomical relationship is ascertained as accurately as possible by keeping the index finger of the left hand in the rectum, and the sound, held by an assist- ant, in the bladder. A transverse incision through the skin and cellular tissue is made in front of the anus. It is always wise to work as close to the rectum as possible, because, with the index finger in this organ to serve as a guide, there is much less danger of penetrating it than there is of penetrating the blad- der. After the skin is incised the cutting instrument should be used as little as possible; it is much less dangerous to bore one's way into the tissues with the finger, aided, if necessary, by the handle of a scalpel. If space will permit, the caliber of the canal should be greater than normal because of the tendency of the tissues to contract during the healing process. Such a dissection as this is long and tedious, and it may be necessary to complete it, because of the exhaustion of the patient, at a subsequent opera- tion. The question of penetrating the uterus, if the cervix is found closed, will also depend upon the condition of the patient. If the shock is already great, because of the duration of the operation, it is best not to open the uterus until some future time. After the canal has been made or reopened it is to be kept patulous by the Sims dilator, or by a strip of iodoform gauze packed into it. I prefer the latter method, changing the dressing for the first time at the end of forty-eight hours, and, subse- quently, every twenty-four hours. Later on the Sims dilator can be advantageously used. In time epithelium forms over the raw surface, and it is surprising how very like normal vaginal mucous membrane the interior of a vagina thus made becomes. The parts must be kept patulous for months by artificial measures, and it is this procedure which greatly taxes the en- durance of the patient. She should be instructed how to insert the Sims dilator, which, if too painful to be worn continuously, should be left in for an hour twice a day. Specular dilatation from time to time may be necessary. Puncture through the rectum or above the pubes, for the pur- pose of reaching the retained discharge, is hardly a justifiable 374 A TEXT-BOOK OF GYNECOLOGY. operation except in extreme cases. I dislike always to drain any cavity into the rectum if such a procedure can possibly be avoided. Fecal contamination is almost inevitable and the prin- ciple of drainage is wrong. Nevertheless, if the tumor bulges into the rectum, and the tissues corresponding to the vaginal tract are limited, this may be the only resource. DOUBLE VAGINA. Double vagina is occasionally met with as one of the anoma- lies of development. In most instances it is associated with a double uterus, though not always. The septum dividing the two vaginæ may be complete or partial, and consists of a double layer of mucous membrane, separated by more or less muscular tissue. Where the septum is incomplete it may be found stretched across the upper, middle, or lower portion of the vagina. Some- times it is perforated. The two sides of a double vagina are usually of unequal size, one being much smaller than the other. This is always the case when the double canal leads up to a one-horned uterus, the side corresponding to the absent cornu remaining rudimen- tary. On the other hand, when the uterus is double, both sides may be fully developed. Each half is generally guarded by a hymen. DOUBLE HYMEN. This rare condition has been met with in different forms. The two hymen may be placed one immediately above the other, or the upper one may be high up, close to the cervix. The latter condition sometimes is very confusing, as was the following case: Mrs. æt. 28, was referred to me by Prof. Walter Wesselhoft of Boston. As a girl she was strong and vigorous, never having suffered from dysmenorrhea; after marriage, soon after which she became pregnant, there was not the slightest history of dyspa- reunia. Pregnancy progressed in a perfectly normal way, and at the end of gestation Dr. Wesselhoeft was called upon to care for her in labor. To his surprise he found at the upper part of the vagina a septum, through which he could not pass the finger. If MALFORMATIONS AND DISEASES OF THE VAGINA. 375 an opening existed, which must have been the case to have per- mitted of conception, it could not be detected by the examining finger. The septum was cut through and the labor terminated by forceps. The patient made a good recovery, and in due time came to Michigan to reside, when she placed herself under my care. I made an examination twelve months after delivery. The upper part of the vagina was narrowed and the septum referred to was perforated by an opening about one-quarter of an inch in diameter. The edges of it were thick and indurated and the cervix impinged upon its upper border. The cervix was badly lacerated, everted, and eroded, which condition, together with the obstacles interposed by the septum, led me to think, on making the first examination, that there was a double uterus. A second examination, however, convinced me that this was not the case. The uterine catarrh was perpetuated by the retained secretions above the septum, and the patient suffered more or less in a general way as a result of this. The preliminary treat- ment consisted of frequent douches and the application of the compound tincture of iodin twice a week; after these applica- tions a strip of iodoform gauze was packed about the cervix above the septum. The gauze afforded good drainage and the improvement was rapid. My intention was entirely to remove the septum and to repair the cervix in the usual way. When I came to operate I found, to my surprise, that the septum was composed of a duplicature of the vagina, folded upon itself in such a way that the bladder and the Douglas cul-de-sac were turned into it. My first incision opened into the peritoneal cavity through the cul-de-sac, so that, after carefully closing it, I desisted from further efforts to remove the septum. I enlarged the opening by nicking it, and with much difficulty succeeded in repairing the cervix. The patient made an uneventful recovery and is now quite well. VAGINAL CYSTS. These sometimes form in the vagina and vary in size from a walnut to an orange. They may result from the persistence of Gartner's ducts, or from occlusion of some of the muciparous follicles. In the first instance they are found on the anterior 376 A TEXT-BOOK OF GYNECOLOGY. vaginal wall at its lower part; if formed by the distention of muciparous follicles they are located in the fornices of the vagina. They contain a limpid fluid which sometimes becomes viscid. When located on the anterior vaginal wall care must be taken not to confound them with cystocele. The introduction of a catheter will enable the physician to differen- tiate the two conditions. The treatment is very simple: they should be cut into, evacuated, and packed with gauze previously dipped in a solution of iodin. HERMAPHRODISM.* This term is applied to that congenital condition of the sexual organs in which the ovaries and testicles exist in the same indi- vidual. True hermaphrodism is extremely rare, yet undoubted cases of it have been recorded. That of Katharine Hohmann is a well-known instance.† Both ovaries and testicles, or but one of each, may exist in the same person. This constitutes true hermaphrodism, and, as I have already said, is an extremely rare condition. Pseudo- or false hermaphrodism is, on the other hand, much more com- mon. Here, owing to malformation, the external genitals re- semble more or less closely the sexual organs of the opposite sex. Thus hypospadiasis in the male may so divide the sexual organs as to make them resemble the vulvar cleft in the female; or the clitoris in the female may be so enlarged as to resemble the penis, while the labia minora, because of their close proximity, are mistaken for the scrotum. If the individual be a male, the testicles will, in most instances, be found in the struc- tures simulating the labia and scrotum. It must, however, be borne in mind that the testicles may not have descended; and that the ovaries may find their way into the pudendal sac. These confusing factors may make it impossible to determine the sex until the age of puberty is reached. The menstrual *" Hermaphroditus was fabled to be the son of Hermes (or Mercury) and Aphrodite (or Venus), and to have united both sexes in one person."—Joseph Thomas. + Thomas and Mundé, p. 119, 1891. MALFORMATIONS AND DISEASES OF THE VAGINA. 377 function will then assert itself if the patient be a female, and the breasts, the face, the form, the voice, etc., will serve as distin- guishing features. Sometimes the uterus and ovaries can be palpated through the rectum. When called upon to determine the sex of an infant too much care, for obvious reasons, cannot be exercised. CHAPTER XXVI. VAGINITIS. The mucous membrane of the vagina is perhaps oftener attacked by inflammation than any other mucous membrane of the body. When thus affected it is known as vaginitis, colpitis, blenorrhagia, or blenorrhea. These several terms are used syn- onymously by different writers to indicate the various forms of inflammation attacking this organ. Anatomy. The peculiar structure of the vagina is one of the reasons why it is so frequently the seat of inflammation. It extends from the ostium vagina to the cervix uteri and con- sists of three coats-fibrous, muscular, and mucous. The fibrous and muscular coats are attached to the ischio-pubic rami, constituting a part of the perineal septum. The mucous mem- brane is lined with squamous epithelium. The posterior wall is about four inches long, being twice the length of the anterior. This throws the anterior wall into transverse ruga, which greatly increase its mucous surface and form nidi for the reception of virus (Fig. 10). Neumann doubts the existence of true muciparous follicles in the vagina.* Von Preuschen maintains that they do exist, but that they are limited to the upper portion of the vagina. There is, however, no question regarding the existence of numerous papilla which cover the folds or rugæ. Varieties.-Vaginitis may be divided into four forms: 1. Simple; 2. Specific or gonorrheal; 3. Granular or papillary; and 4. Senile or adhesive. SIMPLE AND SPECIFIC VAGINITIS. While I believe that these two forms result from entirely different causes-the specific always being due to gonorrheal * Deutsche medicinische Wochenschrift, 1890. 378 VAGINITIS. 379 infection—yet clinically it is often impossible to differentiate them. I therefore deem it more practicable first to study their clinical manifestations conjointly, referring in conclusion to the differential points given by various authors. The causes may be enumerated as follows:- I. Contact with specific poison; 2. Contact with various irritating and mechanical agents used for disinfecting or examining purposes; 3. Contact with discharges from the uterus or from abscesses opening into the vagina; 4. Undue exposure; 5. Excessive coitus; 6. Disordered blood states resulting from phthisis, the exan- themata, etc. 7. Traumatism due to parturition, the use of pessaries, etc. Simple and specific vaginitis may be either acute or chronic and, as the list of causes shows, occur not infrequently as secondary affections. The simple is much oftener secondary. than the specific, resulting from extension of inflammation of contiguous structures, or from contact with discharges issuing from the uterus or pelvis. Undoubtedly the condition of the system has much to do with the acuity of the symptoms. A simple chronic vaginitis may have existed for an indefinite period in one otherwise perfectly well, when, if for any reason the patient's vitality is reduced to a certain point, it will assume the form of an acute inflammation upon the slightest provoca- tion. The acute form, unless arrested by proper treatment, rapidly passes into the chronic. Pathology.—The characteristic changes attending inflam- mation of any of the mucous surfaces, modified only by the anatomical structure of the parts involved, take place in vagini- tis. The parts are at first dry, hot, and congested. This con- gestion is, in due time, relieved by an exudation, which is at first serous but, in a few days, becomes purulent. The duration of the first stage is variable-from a few hours to several days. The extent of tissue involved depends both upon the cause and the vitality of the patient. Thus the involvement is usually greater and more serious in the specific than in non-specific in- 380 A TEXT-BOOK OF GYNECOLOGY. flammation; and the sub-mucous structures are more apt to be implicated when the affection occurs as a complication of the exanthemata, or puerperal fever. A true phlegmonous process may be inaugurated by the involvement of the deeper structures. Not infrequently the epithelium is shed in patches, leaving the underlying surfaces exposed; or occasionally the entire epithe- lial layer of the vagina is cast off en masse, owing to the intensity of the disease. The inflammation may extend over the entire mucous area of the vagina, as well as that of the vulva and urethra, or be limited to the vaginal fornices. Symptoms. The intensity of the symptoms depends in large measure upon their acuity. The onset of an acute attack is usually characterized by a slight chill or chilliness. This is soon followed by a sensation of heat or burning in the region of the vagina or vulva, which is often very intense. There is heaviness and frequently an aching sensation in the pelvic region, which extends down the thighs or radiates upward. Sooner or later a more or less profuse discharge occurs, which is often exceed- ingly excoriating and gives rise to intense pruritus. Dysuria, from involvement of the urethra, is a frequent complication, and when the cause is gonorrheal infection it may be most dis- tressing and obstinate. The local symptoms become less marked as the disease assumes a chronic form, until finally they disappear entirely. The dis- charge may, however, continue in the form of a leucorrhea for an indefinite length of time after the local suffering ceases. Physical exploration will reveal one or all of the changes men- tioned under the head of pathology. If the examination be made during the first stage of the disease the parts will be found hot, dry, and tender. Later on they are bathed in a profuse secretion of purulent matter, which escapes upon separating the labia. By drawing the finger along the tract of the urethra pus is often forced from it.* A specular examination will usually * In this connection the observations of Horand are valuable (L'Union Médical, Aug., 1889). Of 483 women examined there was a urethral discharge in 143. Horand, while believing that it was frequently due to gonorrhea, maintains that such discharge often results from a simple folliculitis. This discharge is occasionally seen in virgins with absolutely no signs of inflammatory involvement of either the urethra or the vagina. VAGINITIS. 381 reveal abraded patches, or, possibly, the evidences of true ulceration. Involvement of the cervix is also frequently ob- served. During the acute stage a specular examination, because of the pain produced, is hardly justifiable. Later on this instrument is useful in differentiating endometritis and pelvic abscess from vaginitis. Pelvic abscess opening into the vagina has more than once been mistaken for the latter condition. These cases, because of the fact that vaginitis is frequently ex- cited by the discharge from the abscess, are often misleading. Differentiation Between Simple and Specific Vaginitis.— This question has already been discussed in Chapter IV, to which the reader is referred. It must be admitted that few investiga- tors are as sanguine as Aubert, whose opinion is there given, in relying upon the gonococcus of Neisser as furnishing conclu- sive evidence of the specific nature of vaginitis. Thus, Vibert and Bordas * affirm that gonococci are practically indistinguish- able by any means yet known to us from other forms of micro- organisms, and that there is no other way by which, in medico- legal cases, the two forms of inflammation can be distinguished the one from the other. Currier † believes that specific vaginitis is always caused by the gonococcus of Neisser, but admits that it is not always present in gonorrheal pus; Ollivier asserts it as his belief that in the present state of knowledge we cannot absolutely demonstrate the infectious principle of gonorrhea; and, finally, Thomas and Mundé, in their latest work affirm that differentiation between the acute and subacute forms of the two affections can seldom, if ever, be made. L All of the authorities quoted are quite agreed that the cause of specific vaginitis is always a specific discharge, though nearly if not quite all admit that non-specific vaginitis occasionally gives rise to urethritis in the male. There certainly exists much confusion regarding the subject, and the medico-legal expert should give his testimony with much caution. In cases of rape, for instance, or where the chastity of a girl or woman is at stake, the responsibility of the medical expert is very great. * Le médecine moderne, Paris, 1890. † Medical News, 1889. Op. cit. 382 A TEXT-BOOK OF GYNECOLOGY. It is no small thing to ruin the reputation of either a man or woman by evidence based upon a pathology as yet unsettled. There are, however, symptoms other than those obtained by microscopical examination of the pus which will at least lead the physician to suspect the form of vaginitis met with. Of first importance is the infectious character of the discharge. There is no question but that specific vaginitis is infinitely more liable to excite urethritis in the male than is the simple form. In proof of this, it is only necessary to remind the reader of the frequency of vaginal catarrh in married women, and the comparatively few cases of urethritis in the male resulting from the same; whereas, a single cohabitation with a prostitute will, in at least a goodly per cent. of cases, give rise to virulent urethritis. The acuity and intensity of the symptoms will lead us to suspect the specific nature, though simple vaginitis not in- frequently runs a course quite as acute and virulent as the specific form. Urethral complications occur oftener, as has been shown, in the specific form of the disease. Indeed, the inflammation may, in gonorrhea, be confined almost entirely to the urethra. Other circumstances should be noted. For instance, if the foregoing symptoms suddenly develop in a woman who has never before suffered from vaginal discharge, we are at least warranted in suspecting gonorrhea. On the other hand, if a girl preserves all of the evidences of virginity, as shown by the hymen, etc., and if her reputation is such as to make illegitimate intercourse improbable, we ought at least to give her the benefit of the doubt, and consider the case one of simple vaginitis. (C Course and Termination.-Gonorrhea is supposed to be a self-limited disease. Until 1873, in which year Noeggerath wrote a most startling paper on the subject, its remote effects in the female were considered most insignificant. In the paper referred to Noeggerath makes the following affirmation : . I believe that I do not go too far when I assert that of every one hundred wives who marry husbands who have previously had gonorrhea, scarcely ten remain healthy; the rest suffer from it, or some other of the diseases which it is the task of this paper to describe. And of the ten that are spared, we can positively VAGINITIS. 383 affirm that in some of them, through some accidental cause, the hidden mischief will sooner or later develop itself." There can be no doubt that gonorrhea is frequently respon- sible for perimetric inflammation and pyosalpinx. I have more than once been able to trace the mischief to this source, and while engaged in writing this chapter I had occasion to operate for Dr. E. F. Chase, of Dexter, Mich., on a patient who presented the following history: Though married, she was but seventeen years old, and not well developed for one of her years. Pre- viously to marriage Dr. Chase had treated the husband for gonorrhea, and all discharge had ceased. Soon after marriage, however, the patient was taken with severe inflammatory symp- toms, accompanied with agonizing pain in the pelvic region. Her symptoms grew from bad to worse, the temperature running up very high and presenting all the characteristics of pyemia; the pulse became more and more rapid, and her general appear- ance clearly indicated a fatal termination if the progress of the disease were not arrested. An examination under chloroform revealed the usual board- like hardness of the pelvic roof. I opened the abdomen two days after making the first examination (about six weeks from the onset of the first symptoms) and dug the distended tubes and the friable ovaries from a mass of inflammatory exudates. Many intestinal adhesions were separated, the abdomen washed with sterilized water, a drainage tube inserted, and the wound closed. The patient nearly died from shock while on the table, the operation requiring fifty minutes, but rallied, only to suc- cumb fifteen hours later. Cases like the above, I am sorry to say, are only too common. There was no history of traumatism or of other possible cause of the mischief. The symptoms came on insidiously and were preceded by a vaginal discharge. Noeggerath is probably right in maintaining that gonorrhea may remain latent in both the male and female for almost an indefinite length of time. Lawson Tait, in support of the teach- ings of Noeggerath, contends that gonorrhea is responsible for infinitely more suffering, and is infinitely more serious in its con- sequences, than is syphilis. More recently, however, there is a 384 A TEXT-BOOK OF GYNECOLOGY. tendency to question the sweeping assertion of Noeggerath and Tait as to the almost inevitable transmission of the disease from the male to the female. Gonorrhea in the male is, unfor- unately, too common to justify it. Bantock, of London, who has certainly had extraordinary opportunities for observation, informs me that, in England at least, Noegerrath's statement does not hold good. While admitting, then, that specific vaginitis frequently does give rise to serious and often fatal pelvic complications, it is prob- able that both forms of the inflammation may run their course without extending above the vagina. GRANULAR OR PAPILLARY VAGINITIS. Definition. These terms have been applied to a form of in- flammation attacking the vagina characterized by a hypertrophy of the vaginal papillæ. For a long time it was supposed to be a hypertrophy of the muciparous follicles, but, if the teachings of Neumann are correct, these follicles, if they exist at all in the vagina, are very limited. The papillæ, on the other hand, are found scattered over the transverse folds in large numbers, and, in all probability, the granular appearance which characterizes the disease is due to their enlargement. There is a certain resemblance between granular vaginitis and follicular vulvitis. Both are much oftener met with during pregnancy, and both commonly continue until utero-gestation is terminated. A follicular vulvitis frequently implicates the vagina, and, conversely, I have seen granular vaginitis ending in the former condition. The physiological congestion of pregnancy tends to produce both diseases. It is by no means peculiar to the pregnant state. One of the worst cases that I ever met with occurred in a virgin twenty-six years of age. The impression obtained on digital examination was not unlike that experienced on scraping the finger over the surface of a beef's.tongue. Symptoms. The symptoms do not differ essentially from those of the two forms of vaginitis already studied. In the cases coming under my observation the acute manifestations were not so marked, but the irritation and pruritus were infinitely greater. VAGINITIS. 385 The enlarged papillæ can be plainly seen and felt. They extend from the ostium vaginæ to the cervix, and sometimes stud the entire surface of the latter. TREATMENT OF VAGINITIS. The treatment of the three forms of vaginitis which have been considered is so much the same as to make a separate con- sideration of each unnecessary. During the acute stage quiet must be observed, the patient being confined to her bed for two or three days. Aconite, belladonna, and cantharis are the reme- dies oftener useful in controlling the pain and the slight fever present. A bichlorid douche (1:3000) should be used every five or six hours. Instead of the bichlorid the fluid extract of hydrastis canadensis is recommended by Cowperthwaite.* The injections, whatever medicament is used in the water, must be thoroughly made according to the method described in chapter X. Later on, when the discharge assumes a purulent char- acter, a solution of calendula and glycerin can be advantageously used after the parts have been washed with the bichlorid solu- tion. When the acute symptoms have subsided the douches need not be administered oftener than twice a day. I then apply the nitrate of silver after the method described by Skene. The parts are exposed by the aid of a Sims speculum and a one-grain solution of the silver is sprayed with a good atomizer over the whole vaginal surface. The force of the atomizer causes the fluid to come in contact with the vaginal folds much more thoroughly than is possible by simple applications and makes the stronger solutions unnecessary. This treatment is repeated once a day until the pain is relieved, after which the so-called dry treatment" is to be substituted for it. This consists of various preparations of powder sprinkled upon a dry tampon, which is inserted in such a way as to keep the opposing vaginal walls separated. For this purpose I prefer iodoform and bismuth, equal parts. The tampons should not be worn longer than twenty-four hours, when they are to be removed, the vagina * "A Text-book of Gynecology," p. 99, 1888. 25 386 A TEXT-BOOK OF GYNECOLOGY. washed with a douche, and new ones substituted. This simple method, persevered in, has proved more useful in my hands than any other yet experimented with. Granular vaginitis is the most obstinate of all forms to treat, but when it occurs as a complication of pregnancy it usually terminates with the pregnancy. Montgomery recommends the thermo-cautery for the purpose of destroying the papillæ. Unless used with the utmost caution this strikes me as a dangerous ex- pedient. When vaginitis becomes chronic and there is much relaxation of tissue, applications of tannin and alum are often decidedly beneficial. Therapeutics of Vaginitis. Aconite.-Non-specific vaginitis resulting from cold, espe- cially in the beginning of the attack; painful urging to urinate; the vagina is hot, dry, and sensitive. Belladonna.-Shooting pains in internal organs at every step; dryness of vagina, with burning and stinging; URGING, AS IF EVERYTHING WOuld be forced FROM THE VULVA; aggravated by sitting bent and walking; ameliorated by lying down and sitting erect; fever with marked cerebral symptoms. Mercurius .cor.-Inflammation of vulva; vagina swollen, red, hot, with discharge of watery mucus, then of mucus tinged with blood; forcing downward as in labor; slight hemorrhage from vagina. Cantharis.-Swelling of vulva and vagina with irritation; burning in vagina and vulva, with a thick, white discharge; swelling of neck of uterus, with burning in bladder; DYSURIA ; pruritus of vagina; menstruation too early, with great soreness of breasts. Sepia.-Soreness of labia, perineum, and between thighs, with redness; yellow leucorrhea, ACRID BEFORE MENSES, WITH SORENESS of pudenda; purulent leucorrhea; symptoms of pressure as if everything would protrude from the vulva, with all-gone sensation at pit of stomach. Hydrastic can.-Chronic specific vaginitis associated with ulceration of the cervix and prolapse of the uterus; thick, VAGINITIS. 387 tenacious leucorrhea; vaginitis is associated with great prostra- tion and palpitation, or with derangement of the liver, giving rise to constipation, hemorrhoids, etc. Kreosote.-ITCHING AND SMARTING IN THE VAGINA, WORSE AT NIGHT; GENITALS SWOLLEN AND HOT; ON URINATING, SORE PAINS IN VAGINA; voluptuous irritation deep in vagina; white discharge from vagina preceded by pain in small of back; yellow leucor- rhea staining linen, with weakness in legs; great acridity of leucorrhea, which causes itching and biting of external genitals. Arsenicum.-Shooting pains from the abdomen into the vagina, with profuse yellow, corroding leucorrhea; sudden profuse discharge of dark blood from vagina; menses too early and too profuse, or pale and scanty; PROSTRATION AND EMACIA- TION. Calcaria carb.-Scrofulous diathesis; MENSTRUATION TOO EARLY AND TOO PROFUSE; general weakness with exaggerated desires; constant aching in the vagina; profuse leucorrhea like milk; burning in labia before menstruation; discharge of bloody water from vagina in elderly women, with pain in small of back, as if menses would appear. Helonias.-Offensive leucorrhea; very little exercise tends to produce a flow of blood; vaginitis with uterine prolapse and a sensation as though there were a heavy weight over the chest, on the sternum, and a feeling as though the chest had been gripped in a vice (Farrington); persistent itching about the genitals, with or without the formation of blisters or sores; aphthous vaginitis and erythema of external genitals (L. L. Danforth). Thuja.-Extreme sensitiveness of vagina; mucous leucor- rhea; cauliflower excrescences, bleeding freely; condylomata which are moist, suppurating, and give rise to an exceedingly offensive discharge. Sulphur.-Menses too late, of short duration, or suppressed; bearing down in vulva toward genitals; leucorrhea of yellow mucus, corroding and preceded by pains in abdomen; tendency to eruptions. Consult:-Rhus tox, conium, kali carb., croton tig., cimici- fuga, gelsemium, and kali mur. CHAPTER XXVII. SENILE OR ADHESIVE VAGINITIS. General Considerations and History.-The dearth of liter- ature treating of this subject fully justifies, I think, the insertion in full of the following, which was first published in the Homeo- pathic Journal of Obstetrics for March, 1889. Dr. Alfred McClintock, at the June 11, 1870,* meeting of the Dublin Obstetrical Society, presented a paper entitled "Senile Contraction of the Vagina," in which he describes certain pathological changes corresponding to those resulting from the type of inflammation designated by the title of this chapter. FIG. 66. Section of VAGINA; c, c, Cicatricial Bands.† (Wood.) Dr. McClintock first refers to the frequency of contractions, contortions, and occlusions of the vagina resulting from cica- * Dublin Quarterly Review, vol. L, p. 17. †The patient from whom this illustration was taken presented herself at the University clinic with complete laceration of the perineum, the rent in the recto-vaginal septum extending to the cicatricial projection. Before the laceration could be repaired I found it necessary to overcome the contractions by cutting them and dilating the vagina. My object in presenting this cut is to show, by contrast, the difference between this not unusual form of contraction and cicatrization and the rarer types seen in Figs. 67 and 68, which McClintock and two or three other writers have described under different names. 388 SENILE OR ADHESIVE VAGINITIS. 389 trices and adhesions. sloughing of the vagina are familar to all practical gynecologists and obstetricians, as are also those minor forms of contraction resulting from projecting transverse folds, which present to the finger a sharp, crescentic edge like that shown in Fig. 66. These sequelæ of inflammation and In the paper referred to, the writer next reminds the reader of the well-known fact that the upper part of the vagina is, normally, both capacious and distensible. In both married women and in virgins the finger can be passed freely into all of the fornices, between the cervix and the vaginal walls. In the peculiar form of vaginitis under consideration the conditions are quite altered. "There is," says McClintock, "a progressive diminution of the caliber of the vagina-not throughout its entire extent- but commencing at its summit and slowly advancing downward. When the contraction has reached the level of the os tincæ, the introduction of the finger into the vaginal cul-de-sac around the cervix becomes quite impossible, this part (cervix) being so closely embraced by the broad, ribbon-like structure. With the persistent increase of the constriction the os and cervix become quite encapsulated, and beyond the reach of touch or sight. The foramen through the stricture, in two of my cases, was so small as barely to admit a probe, and might very readily have been mistaken for the os uteri itself. How much lower down this process of contraction may extend I cannot at present say, the cases which have longest been under my observation being married women, and I should imagine that sexual inter- course would tend to hinder or retard the progress of the con- traction downward." Simpson,* in a chapter devoted to "Closure and Contraction of the Vagina as a Result of Inflammation, and Independently of Pregnancy," introduces his subject by describing, first, those forms of vaginal inflammation occurring oftener in chil- dren, and which result in contraction and closure of the canal at its lowest point. This form of inflammation is also frequently met with and is easily recognized. I desire, nevertheless, to quote in detail from Simpson: † "You may meet likewise among * "Diseases of Women," vol. III, p. 269. † Ibid., p. 260. 390 A TEXT-BOOK OF GYNECOLOGY. adults with cases of a kind of adhesive or obliterative vaginitis of an analogous type. But the disease in adults differs from the disease in infants in one or two important respects. In infants the inflammatory closure is usually limited to the very orifice of the vagina, and produces complete occlusion of the canal. In adults it generally commences at the upper part of the vagina, and spreads gradually downward, and seldom causes complete closure. In infants there is commonly cohesion merely of the apposed sides of the orifice of the vagina, without any tendency to circular contraction in the caliber or circumference of the ori- fice. In adults, on the contrary, a state of inflammatory cohe- sion and obliteration is almost always attended with a simulta- neous tendency to circumferential contraction of the canal at the site of the disease, so that when it is limited, as it often is, to the top of the vagina, the os uteri is felt drawn up, as it were, to the apex of a narrow, conical, or funnel-shaped cavity. There is evidently a tendency in some rare cases to the occur- rence of obliterative inflammation of the uterine canal itself; for FIG. 67. CONTRACTED VAGINA. Dotted line showing normal outline of Vagina. (Wood.) in the instances I refer to you may open up the canal repeatedly with the uterine sound, and yet the patients will occasionally come back to you with perfect amenorrhea, and when you pass the sound along the canal you will have the sensation imparted to you of the instrument separating the adher- ent surfaces, just as you can feel the adhesions of the vagina separating under the pressure of the finger." McClintock's paper was published in 1870. Simpson's work was not issued until 1872, but the editor, A. R. Simpson, states, in his preface, that "the greater number of lectures con- tained in this volume appeared in the Medical Times and Gazette during the years 1859-1861." Whether or not this particular lecture was published at that time I do not know. SENILE OR ADHESIVE VAGINITIS. 391 At any rate, McClintock makes no reference to it in his paper. I have thus quoted somewhat at length from these two writers, because they are the only ones in the whole range of literature which I have traversed who give anything like a comprehen- sive description of the peculiar and not altogether rare condition under consideration. Prof. A. J. C. Skene presented in 1877 a most admirable essay to the American Gynecological Society on "Cicatrices of the Cervix Uteri and Vagina."* In it the author deals especially with those forms of contraction occurring below the fornix vaginæ which result usually from parturition. Three clinical cases are recorded by Skene, one a nullipara who had during childhood what was supposed to be a "typho-malarial " fever, followed by pelvic inflammation and abscesses—a point worth noting in connection with the cases whose records I shall pre- sent. In this essay no mention is made of McClintock's and Simpson's articles; nor does Skene in his latest work † have anything to say of "adhesive vaginitis." Bedford, in a series of clinical cases, describes adhesions of the upper portion of the vagina caused by the unskilful use of instruments, but an analysis of these cases shows them to he not unique in their pathology. May,§ evidently deriving his information from Fritsch, dis- misses the whole subject in six lines. Tilt || refers to "vaginal contraction" as a result either of trau- matism or chemical irritants, but says nothing more. Sims ¶ treats of certain unnatural conditions of the vaginal vault, either congenital or acquired, giving rise to sterility, but he conveys to the reader no definite idea of the peculiar vaginal deformity under consideration. Fritsch,** on the other hand, evidently looks upon the lesion * "Transactions," vol. I, p. 91. t "Diseases of Women," 1889. ‡ "Clinical Lectures on Diseases of Women and Children," pp. 347 and 379. 8 "Manual of Diseases of Women," p. 79. “A Handbook of Uterine Therapeutics," p. 241. T "Clinical Notes on Uterine Surgery," p. 342. ** "Diseases of Women," pp. 96 and 98. 392 A TEXT-BOOK OF GYNECOLOGY. as a pathological entity, giving a brief but very good description of it. * Byford's description of vaginal cicatrices is confined to those varieties where there is a "frenum-like projection in the vaginal walls," such as is depicted in Figure 66. Hart and Barbour † say: "The cicatricial contraction of the vagina observed after the menopause is due to senile vaginitis. The epithelium is shed in patches, and the raw surfaces thus produced adhere together (Hildebrandt). This process is similar to that which produces occlusion of the cervical canal after the menopause." Southwick, in his schema of the several varieties of vaginitis, FIG. 68. THE RIGHT AND ANTERIOR FORNICES OBLITERATED, the Left FREE. (Wood.) briefly refers to the senile or adhesive, asserting that" there may be no subjective symptoms whatever." Breisky § has a very interesting chapter upon “Acquired Atresias and Stenoses," and refers to Simpson's article. He offers no observations of his own bearing upon senile vaginitis. Cowperthwaite || gives in substance the brief reference to the condition made by Hart and Barbour, quoting indirectly Hilde- brandt's article. *"The Practice of Medicine and Surgery, Applied to the Diseases and Accidents Incident to Women," 2d Edition. + "Practical Manual of Gynecology," p. 495. "Practical Manual of Gynecology," p. 115. 80 "Diseases of the Vagina," p. 264. || "A Text-Book of Gynecology," p. 98. SENILE OR ADHESIVE VAGINITIS. 393 Winckel,* under the head of " Senile Changes of the Uterus," says: "With the approach of the menopause the uterus begins gradually to decrease in size, at the same time the fornices of the vagina become shorter and narrower and are finally obliterated. The vaginal vault becomes narrowed, thus giving the vagina a funnel shape as it approaches the cervix. . . The lips of the ex- ternal os and the mucous membrane of the internal os lie firmly together, thus preventing the free exit of the secretion, which abundantly accumulates first in the cavity of the fundus, next in the cavity of the cervix, and finally in the narrow vault of the vagina." Winckel gives several interesting illustrations taken from photographs of post-mortem specimens. These, however, do not show the characteristic vaginal changes of the affection under consideration. The foregoing literature is the sum total bearing upon the subject which I have been able to discover. For fear of appear- ing pedantic I shall refrain from naming the many works ransacked in my research, which was not confined to gynecological and ob- stetrical literature alone, but included many miscellaneous vol- umes, society transactions, etc., etc. I have not, however, had access to the article of Hildebrandt, quoted by Hart and Barbour. Diagnosis and Prognosis.-There may be some difficulty in differentiating the affection from malignancy. Indeed, such an error is recorded by Byford. The history of the case, the du- ration of the pelvic symptoms, and the local condition described, should be noted in forming a diagnosis. By carefully observ- ing the peculiar funnel shape of the vagina, the obliteration of the fornices and the absence of involvement of the surrounding tissues, it should not be mistaken for malignancy. There are no features of the lesion suggesting an unfavorable prognosis so far as life is concerned; it may, nevertheless, prove a most obstinate one to treat. Etiology and Pathology.-In 1870 McClintock wrote: "Al- though years have elapsed since I recognized this state of the vagina as a distinct lesion, I can give but a very imperfect account of it. I know nothing of its etiology, nor have I had * "Die Pathologie der Weiblichen Sexual-Organe," 1881. 394 A TEXT-BOOK OF GYNECOLOGY. an opportunity of making an anatomical examination of the parts affected, so that I am equally ignorant of its pathology." Even in the light of our present knowledge, we can speak positively concerning neither the etiology nor the pathology. It. is worthy of note, however, that in two of my own cases, and in one case recorded by Skene, serious pelvic symptoms dated from an attack of continued fever. There is abundance of corroborative testimony showing that any low fever may cause alarming vaginitis with cicatricial contractions lower down in the canal. White and Nélaton have traced such contractions to cholera; Scanzoni, Hening, and Richter to acute exanthemata; Martin, L. Mayer, and Bohm to typhus. The history of a low or continued fever of any kind should not, therefore, be lost sight of in looking for etiological factors, though a larger series of cases than has yet been recorded will be required to determine this point, and the cause will, in many cases, remain obscure. If, in the cases presented by myself, the disease was the sequel of fever, the term senile vaginitis is clearly a misnomer. On the other hand, it is hard to explain why, in advanced age, the fornix vaginæ should take on inflammatory action when all forms of irritation are wanting. Fritsch* observes that cervical catarrh has complicated every case of vaginitis adhesiva seen by him. It is well known, too, that the layer of pavement epithe- lium becomes gradually thinner as age progresses, thus facilita- ting an extension of the catarrh from the cervix to the vagina. The inflammation may be universal or circumscribed. In either event granulating surfaces form in the vaginal fornices which cause them to adhere to the cervix. In this way" the vaginal portion may partially adhere to the fornix, so that iso- lated cords can be felt; or totally, so that the vaginal portion cannot be felt at all." (Fritsch.) Hildebrandt observes that very similar adhesions may occasionally result from ulcerative vagi- nitis, and where they are firm it is probable that a more destruc- tive process than mere abrasion has existed. Again, it would hardly be possible to have the degree of contraction shown in Fig. 67 without secondary cellular infiltration (Ziegler) into the * Op. cit. SENILE OR ADHESIVE VAGINITIS. 395 connective tissue of the mucosa, and often, also, of the sub- mucosa. The existing conditions are difficult to explain on any other hypothesis. Treatment.-There is but little said in the limited literature concerning the management of adhesive vaginitis, and my ex- perience with the disease will warrant me in doing nothing more than suggesting certain general indications. These are:— 1. If the morbid process has given rise to no distress or in- convenience, let it alone. 2. If there is cervical occlusion with uterine tenesmus and general pelvic distress, the stenosis should be overcome. 3. Subdue the existing inflammation and promote absorption of cellular infiltration: (a) by the hot douche; (b) by the medi- cated cotton-wool tampon. 4. Separate adhesions with the finger, knife, or scissors, when the cicatrices interfere with the functions of the bladder or the bowels, or when dyspareunia becomes a prominent symptom. 5. Control reflex and constitutional symptoms with the in- dicated remedy. Illustrative Cases. CASE LVII.—A maiden lady, 52 years of age. Never has been strong. Com- menced to menstruate at thirteen, but was very irregular until sixteen, for which irregularity she frequently took "tansy tea." Until the age of twenty she had frequent attacks of epistaxis, and has occasionally bled from the nose since that time. During her girlhood hysteria was a frequent symptom, particularly before or during the men- strual period; the hysterical explosions were not infrequently followed by decided choreic manifestations, implicating the head, face, and upper extremities. Her menses were fairly regular until the age of thirty-five, at which time she had an attack of what her physician called "typho-malarial fever." Her menses were always more or less scant, and were attended with a good deal of pain. She ceased menstruating two years ago. Her attending physician during the attack of fever was a "Thomsonian." He administered a powerful lobelia enema which excited the most aggravated retch- ing and vomiting, the patient declaring that she vomited some of the injection. At any rate, the prostration following this heroic treatment was both profound and alarm- ing, and she got up from a lingering illness with much pelvic distress. From that time on there has been an aching, pressing, bearing-down sensation in the pelvis, with dysuria, hemorrhoids and prolapse of the rectum. Indigestion from girlhood has troubled her much, there being times, lasting for days or weeks, when the stomach will immediately eject everything. These attacks of vomiting have recurred at variable intervals up to the present time. The food is vomited undigested soon after eating and with but little retching. There is at all times a great feeling of satiety 396 A TEXT-BOOK OF GYNECOLOGY. after a few mouthfuls have been swallowed. The patient is very nervous, suffering much from occipital headache, flushes of heat, and insomnia, the latter symptom being aggravated by the menace and worry incident to the care of a large estate. Upon making a local examination I found the condition represented in Figure 67. As the finger passed into the vagina there was no perceptible induration to the touch, such as is found in constrictions following inflammation with decided cellular infiltration or sloughing (Figure 66). There was, however, a decided narrowing of the caliber of the vagina, this narrowing being much more marked at the os tince than below, so that the canal was funnel-shaped. The fornices of the vagina were entirely obliterated, and the cervix could not be found. Owing to the necessarily unsatisfactory bimanual I at first thought that the uterus was absent. Upon introducing a small virgin specu- lum (Nott's) the entire surface of the vagina was seen to be intensely red and con- gested. A fair idea of the degree of contraction present at the cervix can be had when it is stated that the blades of the speculum could not be separated more than half an inch. There was a small opening corresponding to the external os, but the cervical canal proper was entirely obliterated. Subsequent treatment reduced the tenderness and inflammation so that I succeeded in opening the canal, hoping thereby to relieve the tenesmus and bearing-down sensation. The parts have, under the treat- ment outlined, improved greatly, and the small infantile cervix has been freed from its encapsulation. I should have added that the uterine body is unnaturally small and anteflexed. CASE LVIII.—Mrs. C., æt. 52, and the mother of ten children. This patient pre- sented herself at the clinic of Prof. D. A. McLachlan, on February 8, 1889. Her father died of phthisis, and her mother of cancer. She has three sisters and four brothers, all living. She, also, has dyspeptic trouble dating back to early childhood, for the relief of which she came to Ann Arbor. There is a history of typhoid fever in early life, though the stomach trouble existed before the onset of the fever. Her indigestion frequently gives rise to vomiting, and there is, and has been for years, a persistent acidity of the stomach with water-brash. There is much flatulence with faintness, and an all-gone sensation at the pit of the stomach. Menstruation ceased three years ago. She suffered much from dysmenorrhea, and has had for years marked pelvic distress. I was requested to make a local examination, and found what is very accurately depicted in Figure 68. The upper and right fornices were not obliterated though not as deep as normal; the lower and left were, on the contrary, entirely effaced by the gluing together of the opposing mucous surfaces. The os tince was somewhat dilated, and the cervix had suffered a stellate laceration. The vagina was much narrower than normal, though not as small as in Case LVII. I could not get a good view of the parts with the speculum, but there was much redness and congestion. The patient returned to her home in the interior of the State, and it is not likely that another opportunity for an examination will present itself. The patient, a CASE LIX.-I regret that I cannot furnish full notes of this case. woman 55 years of age, was sent to me for examination by Doctor Mary E. Havens of St. Johns, Michigan. She had had a number of children, and there was much mental and nervous trouble, symptoms of insanity causing her friends much anxiety at times. She came to me with an attendant. There was a history of "inflammation of the bowels," which was probably cellulitis. There was also a bad leucorrhea, and the SENILE OR ADHESIVE VAGINITIS. 397 patient complained much of stinging, burning pains in the region of the uterus and the ovaries. An examination revealed the vagina shaped not unlike that shown in Figure 67, with an evident bi-lateral laceration of the cervix. Her physician in- formed me, some twelve months after my examination, that the local condition had quite disappeared under treatment, and that the patient had greatly improved both mentally and physically. CHAPTER XXVIII. ACUTE INFLAMMATORY DISEASES OF THE UTERUS, THE UTERINE APPENDAGES, AND OF THE PELVIC PERITONEUM AND CELLULAR TISSUE. My experience as a teacher of gynecology convinces me that there is nothing more confusing to the student of medicine than an attempt to follow the ordinary text-book classification of the various inflammatory affections of the uterus and its surround- ing structures; and my experience as a practitioner of gyne- cology is that the time-worn classifications and divisions, while serving a very good purpose on paper, are frequently valueless at the bedside. Acute inflammation of the uterus, were it ever confined absolutely to the endometrium or the parenchyma of the organ, would require practically the same treatment in either event, and, indeed, the treatment of acute endometritis and metritis is not essentially different from that of acute cellulitis and peritonitis. There is in most instances a blending of the pathology of the various acute inflammatory affections of the pelvic organs; and, so far at least as the subjective phenomena are concerned, there is likewise a blending of the symptoms. It is this fact which is so confusing to the ordinary student. In studying in succession, and as distinct and separate lesions, acute and chronic metritis, acute and chronic endometritis (cervical and corporeal), salpingitis, ovaritis, cellulitis, and peritonitis, he becomes utterly swamped in the uncertainty of differentiation. I maintain that this method of teaching is illogical and unscien- tific. The teacher or writer has no right to expect from the student of medicine more than can be done by himself at the bedside. I therefore deem it more practicable to classify the in- flammatory affections of the uterus and periuterine structures according to the acuity or chronicity of the symptoms which 398 ACUTE METRITIS AND ENDOMETRITIS. 399 characterize them, believing both clinical manifestations and pathological blendings justify such a classification. It is for this reason that I have grouped together the several affections em- braced in this chapter. ACUTE METRITIS AND ENDOMETRITIS. Metritis and endometritis are terms used to designate respect- ively inflammation of the parenchyma of the uterus, and of its lining membrane or endometrium. In most of the text-books these disorders are treated of as separate and distinct, and yet, when so dealt with, a comparison of the symptoms of the two affections will show a similarity making them indistinguishable the one from the other, even on paper. The anatomy of the uterus is peculiar, and the relationship of the mucous membrane to the underlying muscular structure differs from that of mucous membranes in general. The mu- cous membrane is, first of all, more dense in character, and it is not separated from the parenchyma by the layer of areolar tissue which underlies most mucous surfaces. Again, the numerous glands which go to make up the mucous membrane are im- bedded more or less in the muscular layer. Acute inflammation of the endometrium will, therefore, inevitably implicate the uterus proper; and, conversely, acute metritis cannot run its course without involving the endometrium to a greater or less extent— hence the absurdity of studying the two conditions as distinct affections. Causes. Any of the following causes may give rise to the in- flammation: Sepsis resulting from parturition" or miscarriage; traumatism resulting from instrumental interference or from immoderate coitus; menstrual suppression; extension of inflam- mation from the vagina or the surrounding cellular tissue; exanthemata. Sepsis is undoubtedly the most frequent cause, and the inflam- mation resulting from it may be of the most virulent character. In the larger number of instances it is due to improper management, either on the part of the physician or the patient, during partu- rition or miscarriage. Retained membranes or clots soon become putrid and set up inflammation with absorption of sep- 400 A TEXT-BOOK OF GYNECOLOGY. tic matter; or the source of sepsis may be the débris result- ing from an effort to remove fibroids. In miscarriages inflam- mation is often induced by getting up too soon. It will require another decade to educate the laity to the necessity of proper cau- tion after miscarriages. The average woman imagines that early abortions require but a short period of rest, and, accordingly, she gets on her feet while the uterus is yet heavy and congested. In this state it is only a step to actual inflammation and, if clots or membranes have been left behind, sepsis frequently super- venes. Non-puerperal inflammation of the uterus rarely runs so in- tense a course as does the puerperal form of the disease. As a complication of the exanthemata it may, however, be very severe. Some women seem peculiarly prone to the difficulty, even the introduction of the uterine sound giving rise to metritis. This is probably because of pre-existing chronic inflammation. Pathology. The essential pathological changes are: great hyperemia of the endometrium, which becomes swollen and softened as a result of edema; infiltration of the subjacent uterine tissue with ecchymoses and, occasionally, small deposits of pus between the muscular fibers; involvement to a greater or less extent of all of the uterine veins and lymphatics. A large accumulation of pus in the uterine wall is of exceed- ingly rare occurrence, though such a case is recorded by Tait.* Symptoms.-The disorder gives rise to symptoms of varying intensity, depending largely upon the cause, and the extent of tissue involved. * In non-puerperal cases, and especially in those due to an extension of the disease from the vagina, the symptoms are not usually urgent. A slight chill ushers in the attack, which is followed by a moderate increase of temperature. The patient will complain of a throbbing pain in the hypogastric region, together with more or less weight and bearing down. The bowels and bladder may become implicated, giving rise to more or less tenesmus and dysuria. On the whole, the constitu- tional symptoms are not severe, and the disease frequently passes * "Diseases of Women and Abdominal Surgery," p. 122, 1889. ACUTE METRITIS AND ENDOMETRITIS. 40I into a chronic form without arousing serious apprehension on the part of either physician or patient. On the other hand, when the cause is septic and the inflamma- tion is puerperal in its origin, it is of most serious import, and, indeed, often fatal. The initiatory chill is marked and is followed by high temperature, rapid pulse, and much local tenderness. The lochia and milk become suppressed and the whole system is profoundly impressed by the septic invasion. The patient often complains of great pain in the back, which radiates to the groin and thighs. The disease frequently involves the peritoneum, when there will be much distention and tenderness with nausea and vomiting. The characteristic peritoneal facies presents, the breath is of a peculiarly sweetish and sickish odor, the prostra- tion becomes more and more profound, and death only too often results. In the non-puerperal cases the discharge is first thin or viscid, but in the course of several days it becomes muco-purulent or purulent. Not infrequently it is exceedingly excoriating and, especially if there be a septic tinge, offensive. A physical examination will reveal at first dryness and heat of the vagina with tenderness of the cervix. The uterus is large and heavy. If it can be gotten between the two hands this increase in size and weight is very perceptible. Differentiation.-There is but one pathognomonic symptom of uncomplicated acute metritis and endometritis, which will serve to distinguish it from pelvic cellulitis and peritonitis, namely, swelling and tenderness of the uterus with mobility of the organ. It is the height of nonsense to affirm, as is done by so many authors, that the constitutional symptoms of puerperal metritis are not so marked as those of pelvic cellulitus and peritonitis. I have many times observed in metritis symptoms infinitely more profound than those resulting from non-puerperal peritonitis and cellulitis, and when it is remembered that metritis is often complicated by para-and-peri-uterine inflammation the uncer- tainty is increased beyond all differentiation by subjective phe- nomena alone. I admit that cases of metritis, cellulitis, peri- tonitis, etc., are occasionally met with, running a course suffi- ciently distinct and characteristic to enable the attendant, by the 26 402 A TEXT-BOOK OF GYNECOLOGY. aid of both the clinical history and a thorough physical exploration, to determine the organ or tissues chiefly involved, and for this reason I shall soon introduce a differentiating table. Unfortu- nately, thorough physical exploration is the last thing to be thought of in dealing with severe pelvic inflammation of an acute character. While granting that refinement of diagnosis is something always to be desired, in the several acute affections now under consideration it is useful as a means of determining the prognosis rather than as a guide for treatment. The prognosis will depend entirely upon the character and extent of the inflammation. In the milder attacks of non-puer- peral metritis it is favorable, though the patient is often left with a chronic endometritis which may continue almost indefinitely. On the other hand, septic metritis and endometritis are always of serious import, and, if associated with the puerperium, fre- quently result fatally. The prognosis is, of course, modified by the existing complications. ACUTE PELVIC CELLULITIS AND PERITONITIS. Since the days of Morgagni, who first attracted attention to pelvic peritonitis by placing on record a case in which adhesions were found, post-mortem, between the right ovary and tube and the colon, and the days of Doherty and Marchal de Calvi, to whom we are indebted for the first intelligent description of pelvic cellulitis, there has existed the greatest confusion regard- ing these two disorders. As in acute inflammation of the uterus and its lining membrane, we have two structures which, though histologically different, are in such close contiguity as to make it impossible for the one to become involved in the inflammatory process without implicating, to a greater or less extent, the other also, and, indeed, all of the pelvic organs-hence the confusion. I grant that in studying these diseases from the standpoint of pathology we find abundance of evidence showing that acute in- flammation may spend its greatest force upon either the pelvic cellular tissue or its investing serous membrane. Furthermore, I grant that, when this is the case, the clinical picture may be such as to enable us to determine which structure is chiefly in- volved. All this is desirable from the standpoint of pathology ACUTE PELVIC CELLULITIS AND PERITONITIS. 403 and diagnosis, but I contend that the two diseases are so often blended as to make this knowledge of but little value to the clinician. The fact remains that, when the clinician goes to the bedside of a woman suffering with acute inflammation of any of the pelvic organs, he is confronted with a condition which demands of him certain duties: first he is required to determine the cause of the mischief and remove that cause as speedily as possible; secondly, he is to contend with the expressions of the disease to which the cause has given rise. The same cause may in one instance result in metritis, while in the next it may give rise to cellulitis or peritonitis. We may, then, be unable to determine the exact pathological changes that have taken place within the pelvis, but, from the standpoint of treatment—and the chief aim of the physician is to cure disease that he cannot prevent-this is not important. In making this statement I am not drawing deductions solely from my own school of medicine, for, in comparing the treat- ment of the several diseases under consideration given by the principal writers of the older school, it will be found that, while the treatment is as variable as the writers are numerous, each practically observes the same principles of treatment in dealing with all forms of acute pelvic inflammation. Modern abdominal surgery has taught us much regarding pelvic inflammation. I have more than once opened the abdo- men expecting to find this or that product of inflammation, only to discover that an entirely different lesion existed. I make this confession unblushingly, for such men as Tait, Bantock, and others of equal eminence, admit the utter impossibility of deter- mining, in the vast majority of instances, the actual changes resulting from pelvic inflammation before the abdomen is opened. In dealing with the sequelæ of inflammation we can conduct the examination under the most favorable circumstances. We can, if necessary, paralyze the abdominal walls with an anes- thetic and bring the pelvic contents within the grasp of the hands. It is, nevertheless, a notorious fact that, notwithstanding the resources permitted by the chronicity of the condition, cer- tainty of diagnosis is often impossible. How utterly foolish it 404 A TEXT-BOOK OF GYNECOLOGY. is, then, in the acute affections, in which we have to rely for diagnosis largely upon subjective symptoms, to affirm dogmatic- ally that this or that tissue or organ is the one chiefly involved! Confusion will inevitably result from such teaching. The student may go to the bedside with a vivid recollection of the parallel differentiating columns given to him by his professor, but he will return from it with a full consciousness that clinical phenomena blend with an obstinate disregard for prescribed rules. I cannot better illustrate the wide difference of opinion that prevails regarding pelvic cellulitis and peritonitis than by quot- ing, somewhat in detail, from two of the latest text-books on gynecology published in the English language. Much the same diversity of opinion prevails in the French and the German literature. Lawson Tait says: says:—* "In the employment of the terms' perimetritis' and 'parametritis,' as introduced by Virchow (who knew nothing of gynecology), and advocated by Matthews Dun- can (who has never had his fingers inside the pelvis from above), we have had intro- duced a wholesale confusion into gynecology which will take many years yet of in- dustrious work to get right. The confusion has been vastly aided by Dr. Emmet's teachings about 'cellulitis.' If 'parametritis' and 'pelvic cellulitis' be relegated to their proper place—and they may be taken to mean the same thing—it is one of the rare conditions we have to deal with among the special ailments of woman. "Perimetritis is a much more fatal disease than is parametritis, and occurs with greater frequency in association with two particular conditions. These are parturition, either at the full time or prematurely, and gonorrheal infection. "Before the light came that was shed on these ailments by modern abdominal surgery, I believed, as others did and do still, that parametritis, or pelvic cellulitis, was a common disease; and in my writings up to 1878 it is evident I confused cases of damaged uterine appendages with 'pelvic cellulitis.' The latter disease is rare, and occurs in two forms, depending for their characters upon the situation of the disease. If it is situated on the inner half of the broad ligament it is to be recognized as a mass lying close to the uterus and in front of it, between the uterus and the bladder, and into the bladder it generally bursts. If it exists in the outer half of the broad liga- ment it is to be recognized as an ill-defined mass, lying at the brim of the pelvis and fading off on that ridge. In this position it bursts over the brim of the pelvis and constitutes the familiar pelvic abscess, whose sinuses go on for years. Suppurating hematoceles of the broad ligament have similar endings. Rarely does the abscess open into the rectum, because it is generally situated far above the rectum and in front of it." *** Diseases of Women and Abdominal Surgery," p. 131, 1889. ACUTE PELVIC CELLULITIS AND PERITONITIS. 405 I next quote from Thomas and Mundé :- * "It has become fashionable of late for many of our most enthusiastic and progres- sive laparotomists to deny utterly the existence of such a pathological condition as cellulitis, except in a few rare instances after parturition, and to assume that all cases of inflammatory exudations in the pelvis, with or without suppuration, are unquestionably intra-peritoneal; that is to say, that all cases of pelvic peritonitis proceed primarily from the Fallopian tubes, and involve secondarily the ovary and the adjacent peri- toneum. Pelvic abscess, as such, exists in the minds of these gentlemen only as a synonym for abscess of the Fallopian tube (pyo-salpinx), ovary, or pelvic peritoneum, any one of which may, by adhesion and perforation, force its way into the pelvic cellular tissue, and thus simulate an abscess resulting from pelvic cellulitis. . . . In our opinion inflammation of the pelvic cellular tissue, with its resultant consequences of dislocation of the uterus, pelvic abscess, and cicatricial induration, occurs inde- pendently by itself, as well as inflammation of the Fallopian tube, ovary, or adjacent peritoneum, with resultant purulent accumulations in these organs. . . . Pelvic peri- tonitis and pelvic cellulitis are, in fact, independent and entirely unassociated diseases, just as pleurisy of one part of the lung may occur at the same time with an inflamma- tion of the substance of the lung at another point." The authors last quoted refer to the statistics of Bernuth, who has recorded the results of "five autopsies by himself, and be- tween twenty and thirty by others, which presented all the signs of pelvic peritonitis and none of cellulitis, although during life the symptoms and signs generally attributed to the latter disease were present." They, however, question the accuracy of a num- ber of the cases quoted, but the doubt expressed only adds force to the argument which I am putting forth. In the first place we are presented, by so good an authority as Bernuth, with the record of a large number of autopsies in which, during life, all of the signs of pelvic peritonitis presented themselves and none of cellulitis; yet, according to Bernuth, the post-mortem revealed exactly the opposite condition in every instance, though Thomas and Mundé reject "a number of cases reported, because not suffi- ciently conclusive." If such uncertainty prevails in dealing with post-mortem cases, how ridiculous it is to study, in the living, pelvic peritonitis and cellulitis as entirely distinct affections. I have been led, therefore, both by personal experience and by a careful survey of the literature, to adopt the plan of presenting conjointly to the student pelvic cellulitis (parametritis) and pelvic * Op. cit., p. 467. 406 A TEXT-BOOK OF GYNECOLOGY. peritonitis (perimetritis), emphasizing this or that symptom which may serve to indicate the tissues chiefly involved, and to treat of acute ovaritis and salpingitis as complications of general pelvic inflammation. Pelvic abscess, which may be a sequel of any form of acute inflammation, and diseases of the appendages, are more appropriately discussed under other heads. Anatomy. If the reader will refer to Fig. 12 he will find the peritoneum, as it is related to the pelvic organs, clearly outlined; FIG. 69. Cuvam pelvic perito neale Cavum pelvis Subpert- toneale ገባ subeu helvis Lameron M.levator unt CROSS-SECTION OF PELVIS. (Luschka.) and on page 50 will be found a description of the pelvic cellular tissue. Let the relationship of the two structures be borne in mind. The cellular tissue surrounds, in greater or less abun- dance, all of the pelvic organs. It is found between the uterus and the bladder, the vagina and the rectum, the folds of the broad ligament, and in the iliac fossæ. It passes by continuity along the posterior surface of the psoas muscles and separates in front the peritoneum and transversalis fascia. It is most abundant between the folds of the broad ligaments; and least so ACUTE PELVIC CELLULITIS AND PERITONITIS. 407 between the peritoneum and the uterus in front and behind-its existence in these localities having been denied by some. In the language of Savage * it “fills up all that part of the pelvic cavity between the pelvic roof and the floor of the pelvis which is not occupied by the viscera, and is the sole bond of union between them." Its function is to steady the pelvic organs and to break the force of the jar which, without it, would be felt at every step. Through it the blood-vessels and lymphatics of the pelvis pass. The peritoneum is everywhere, except along the posterior surface of the psoas muscles, in intimate contact with it. In Fig. 69 the peritoneal and sub-peritoneal cavities formed by this disposition of the cellular tissue and peritoneum are well shown. Frequency and Causes.-Periuterine inflammation is of fre- quent occurrence, and may result from any of the following causes : Parturition; Gonorrhea and extension of inflammation from the uterus; Intra-uterine and vaginal injections; Mechanical injuries; Operations on cervix, fundus, rectum, etc.; Menstrual suppression; Rupture of ovarian cysts, extra-uterine gestation cysts, perfora- tion of the intestine, etc.; Escape of blood from Fallopian tubes and ovary; Intraperitoneal surgical operations. In by far the larger number of cases parturition is the predis- posing cause. The reasons for this are obvious. Gestation has brought about a physiological hypertrophy of all of the tissues of the pelvis-the cellular tissue, peritoneum, blood-vessels, lymphatics, etc. The lymphatics are in a condition readily to ab- sorb septic matter if avenues for the same be furnished, and the frequent lacerations incident to parturition furnish such avenues. Primiparæ are more often the victims than women who have borne a number of children, for the reason that lacerations of- tener occur in the former, and the bruising of the structures *" Female Pelvic Organs." 408 A TEXT-BOOK OF GYNECOLOGY. is greater. The disease has its beginning, in the larger per cent. of cases, on the left side, toward which the occiput is directed in the majority of births. We thus see that the changes incident to child-bearing place the parturient in a state in which the reception of septic mat- ter easily occurs and inflammation is readily excited. Improper care on the part of either the physician or the patient at this time may precipitate an attack of cellulitis or peritonitis. Uncleanliness is the curse of the lying-in room, and although modern antisepsis has done much toward diminishing the fre- quency of this form of puerperal fever,* uncleanliness is still a frequent source of infection. Indeed, all of the factors given in obstetric works as causes, either heterogenetic or autogenetic, of the various forms of puerperal fever, may, under favorable conditions, give rise to the forms of inflammation now being discussed. Puerperal septic infection usually first attacks the uterus and then extends to the periuterine structures. I have already, in the chapter devoted to vaginitis, dealt in detail with gonorrhea and its tendency to invade the pelvis. In the light of present evidence there can be no doubt that gonor- rhea, starting in the vagina, frequently gives rise to disease of the tubes, and subsequently to peritonitis and cellulitis. Intra-uterine injections are so liable to result in mischief that many specialists have discarded them entirely. Unless used with the utmost care the fluid is liable to pass through the Fallo- pian tubes into the peritoneal cavity. One of the sharpest attacks of inflammation with which I have had to deal came about in this way. Vaginal injections immediately after coitus, for the purpose of preventing conception, are not infrequently responsible for severe and fatal cases of inflammation. Cold water at this time, and for the purpose mentioned, is especially harmful and should never be used. Operations upon the cervix, fundus, rectum, etc., have more * The Royal College of Physicians of England has abandoned the term “ puer- peral fever," and has substituted for it the terms, "puerperal cellulitis,” “puerperal peritonitis," "puerperal metritis," "puerperal septicemia," "puerperal pyemia," etc. ACUTE PELVIC CELLULITIS AND PERITONITIS. 409 than once been followed by inflammation of the periuterine tis- sues higher up. The manner in which the broad ligaments ex- tend down on either side of the cervix will readily explain why operations upon the latter so often set up cellulitis in the broad ligaments. Even slight operations upon the rectum have re- sulted in fatal cellulitis. Menstrual suppression, from undue exposure or otherwise, is an important etiological factor. It is but a step from the physio- logical congestion of menstruation to inflammation, hence the danger of an acute suppression. Rupture of any pathological growth, or of the hollow viscera, into the peritoneal cavity, first gives rise to peritonitis and then to cellulitis, except in cases of Fallopian pregnancy which pri- marily rupture into the folds of the corresponding broad liga- ment. In the latter event cellulitis is first established, though it may not be of serious import. Blood may find its way into the peritoneal cavity through the Fallopian tube, or by escaping from a ruptured Graäfian follicle. The amount of irritation excited depends upon the nature and quantity of the fluid: if it is fresh and bland, the peritoneum, with its wonderful absorbing powers, will take care of a large quantity of it without serious trouble; if, on the other hand, it proceeds from a contaminated uterine cavity, a very small amount may excite alarming peritonitis. Pathology. When the pelvic peritoneum is first attacked (pelvic peritonitis) the membrane becomes hyperemic, red, and dry. Sometimes the engorgement is so great as to produce a rough granular condition of the surface, with here and there a red punctate patch. This is the first stage. In the second stage the engorgement is relieved by an exuda- tion of lymph, plastic in character. It glues the apposing sur- faces together and gives rise to firm adhesions; or the exuded lymph may be serous, or sero-purulent, in character, gravitating into some of the pelvic pouches, usually into the Douglas cul- de-sac. In time this becomes consolidated into a firm, dense mass, matting together the pelvic organs and forming adhesions between them and the intestines. The pelvic cavity may be entirely cut off from the abdominal cavity proper by adhesions d FIG 1 FIG 2 PLATE II. B FIG 3 B. * B. FIG 4 F165 TOPOGRAPHICAL RELATIONS OF THE PELVIC PERITONEUM AND CELLULAR TISSUE, SHOWING SEATS OF EXUDATION. (Fritsch.) Fig. 1. Pelvic Cellulitis.-Vertical section of pelvic organs, showing (e) exudation into the cellular tissue before and behind the uterus and into the anterior abdom- inal wall. a-b shows plane of transverse section in Figs. 3, 4, and 5: Fig. 2. Pelvic Peritonitis.-Vertical section showing (e) exudation in Douglas's pouch, separated from healthy peritoneal cavity by adhesions. Fig. 3. Transverse Section Through Normal Pelvis.-u, uterus; r, rectum; b, bladder; u.-r, utero-rectal ligaments; r. 7, round ligaments; b. 7, broad ligaments. Light spaces show sections of peritoneal pouches. Fig. 4. Pelvic Cellulitis.-The same as Fig. 3, with small exudation (e) to left of broad ligament. Fig. 5. Pelvic Cellulitis.-The same with large exudation (e) in right broad ligament extending into the cellular tissue of the anterior abdominal wall, and distorting the pelvic peritoneal pouches. ACUTE PELVIC CELLULITIS AND PERITONITIS. 4II P thus formed. (Plate 11, Fig. 2.) This condition is sometimes spoken of as encysted serous perimetritis. These accumulations may remain indefinitely, distorting the pelvic cavities and impinging upon the various surrounding structures; or they may suppurate and burst either externally or into the rectum, vagina, or bladder. Rupture rarely takes place into the general peritoneal cavity. The foregoing are the usual changes. Certain modifications are, however, of frequent occurrence. In virulent septic cases, for instance, the fluid, instead of becoming adhesive, is flocculent and pultaceous, so that the adhesions, not being firm, readily break down. In the event of recovery the fluid is absorbed. In all instances the areolar tissue is more or less involved. In pelvic cellulitis we may also have three stages-congestion, exudation, and suppuration. Suppuration is, however, absent in the majority of instances, though it occurs oftener than in pelvic peritonitis. If a digital examination be made soon after the onset of the attack, the swelling will be found soft and elastic. This intumescence is of short duration, and very soon the swell- ing becomes hard from pouring out of the serum. In the worst cases the tissues may slough, as occurs in anthrax or phlegmonous erysipelas. The extent of the exudation is variable, as is shown in Figs. I, 4, and 5, of Plate 11. It may be limited to a small tumor in one of the broad ligaments, which pushes the uterus to the op- posite side; or it may dissect up the lateral attachment of the ligament, extending into the cellular tissue of the anterior ab- dominal wall. Indeed the cellular tissue of the entire pelvis may become involved, fixing all of the organs immovably. If resolution ensue, the inflammatory exudates are largely absorbed, though there is left behind, in the majority of in- stances, a contractile fibrous deposit. This is cicatricial tissue, and, if in one of the broad ligaments, draws the uterus to the corresponding side, thus producing latero-version; or, if in the utero-sacral ligaments, the contraction draws the cervix back- ward and, providing the fundus is not bound down, throws it forward on the bladder. Suppuration, which occurs oftener in parturient cases, does 412 A TEXT-BOOK OF GYNECOLOGY. not usually ensue before the tenth day. The extent of tissue destroyed varies greatly, so that the resulting abscess may be either circumscribed, or large enough to fill the entire pelvis. The most frequent exit of the pus is above Poupart's ligament; next in order of frequency come the rectum, vagina, bladder, anus, and saphenous openings. As in peritonitis, rupture rarely occurs into the free peritoneal cavity. It is held by many writers that in non-puerperal cases rupture externally seldom if ever takes place. This has not been my observation, for in two cases of pelvic abscess operated upon by me the patients were virgins. In one there were several si- nuses and the abscess communicated with the bowel, so that fecal matter escaped with the pus. Let it be remembered, however, that in non-puerperal cases suppuration is the exception to the general rule, and that in most instances pelvic peritonitis and cellulitis run their course without the formation of pus. puerperal inflammations, on the other hand, it is claimed that sup- puration occurs in at least fifty per cent. of all cases. Again, let what has already been said regarding the blending of the patho- logy of the two forms of inflammation be borne in mind. As I have endeavored to show, it is often impossible to determine, even after the abdomen is opened, whether we have to do with the sequelæ of peritonitis or of cellulitis. In Symptoms.-Acute pelvic peritonitis and cellulitis give rise to certain symptoms sufficiently characteristic to call for careful consideration. I nevertheless warn the student that, if he rely implicitly upon any group of symptoms as pathognomonic of the condition, he will do so at the risk of being misled. I have more than once, in both clinical and private practice, met with cases in which the products of inflammation distorted all of the fornices of the vagina, though no history of inflammation could be elicited. And I remember seeing a patient in Leopold's clinic at Dresden whose entire pelvis was filled with an organized exudate, yet the woman, a fairly intelligent German, could not remember that she had suffered from anything more than an indefinable bearing-down sensation. Patients thus affected seek relief because of more or less local distress, when an examination ACUTE PELVIC CELLULITIS AND PERITONITIS. 413 will reveal, what the clinical history does not suggest, the ex- istence of the products of inflammation. There can be no doubt, then, that even a severe attack of pelvic peritonitis or cellulitis may run its course without giving rise to symptoms of sufficient intensity to attract attention to the pelvic organs. It may be that in many instances the patient forgets that at some previous time she suffered more or less pain and tenderness in the hypogastric region; or, possibly, the indis- position dates back to some confinement which, for reasons un- suspected at the time, kept her from convalescing as she should. In other instances we may be able to ascertain that the patient has had an attack of "inflammation of the bowels," possibly at or near the menstrual period, which was nothing more nor less than some form of periuterine inflammation. The symptoms which especially lead us to suspect acute pelvic peritonitis and cellulitis may be enumerated as follows: Chill; Fever; Pain ; Tenderness; Vesical and rectal irritation; Tympanites; Peritoneal facies; Nausea and vomiting. The intensity of the chill is variable and is probably most marked when the cellular tissue is first attacked. The early symptoms of inflammation attacking structures of similar forma- tion throughout the body are generally similar in character. Thus the characteristic chill of pneumonia is decided, while that of pleurisy is erratic and slight. In the first instance, we have in the lungs a structure not unlike the pelvic cellular tissue; while in the second, the pleura, which is a serous membrane, corres- ponds to the pelvic peritoneum. Therefore when the peritoneum is the primary seat of inflammation the initiatory chill may be nothing more than a sensation of coldness, which is soon for- gotten. The thermometric range is quite as variable as is the chill. It may range from subnormal to 106°, or even higher. In the 414 A TEXT-BOOK OF GYNECOLOGY. worst cases of septic peritonitis it is sometimes sub-normal, though as a general rule the higher the temperature the more serious is the attack. This is emphatically so if it remain per- sistently high, for a long-continued elevation of temperature is in itself an element of danger. The temperature immediately following the chill usually ranges from 102°-104°; that of non- septic peritonitis is somewhat higher than non-septic cellulitis. The pulse is a much more reliable indication as to the serious- ness of the attack than is the temperature. The former ranges from 110-140 and may be full and compressible; or small and wiry-the characteristic peritoneal pulse. Great rapidity of the pulse is always an ominous symptom. * The degree of pain and tenderness depends in large measure upon the extent of peritoneal involvement. It may amount to nothing more than a local distress or bearing-down sensation, or it may be so intense as to give rise to the most excruciating suffering. I have seen it so great as to make it almost impos- sible to quiet the cries of the patient even with full doses of morphia. It is usually worse when the ovaries and tubes are involved. The tenderness is often so great over the lower surface of the abdomen as to make contact of any kind intoler- able. In peritonitis or bilateral cellulitis both thighs are drawn toward the abdomen, so as to relax the parts as much as pos- ible. When the cellulitis is limited to one side the correspond- ing limb only is retracted. Vesical and rectal irritation, when present, result either from direct involvement of the bladder and the rectum in the inflammatory process, from direct pressure upon them by the exudates, or from displacement caused by secondary retraction. There is no more frequent cause of dysuria than shortening of the utero-sacral ligaments by inflammation. The cervix is drawn backward and the neck of the bladder is so stretched that micturition becomes both difficult and painful. * This statement is not absolutely true in peritoneal surgery. In some of my cases of abdominal section, in which the convalescence was uninterrupted, the pulse ranged from 120-140, without any increase in temperature, for two or three days after the operation. ACUTE PELVIC CELLULITIS AND PERITONITIS. 415 In septic cases an offensive and prostrating diarrhea may be a feature of the disease. Tympanites, the so-called peritoneal facies, and nausea and vomiting can very appropriately be considered together, because all depend chiefly upon general peritoneal involvement. The distention is sometimes very great-so that coils of intestine can be seen through the tense abdominal walls. Although the expression is characteristic, it is hard to describe the facies of peritonitis. There is a peculiar anxiety depicted in the coun- tenance, which is made more striking by dark areolæ about the eyes. So long as the disease is limited to the pelvis, nausea and vomiting are not marked symptoms, unless, indeed, an inflammatory band has obstructed the bowel, or the ovary is seriously affected. In general peritonitis, on the other hand, nausea and vomiting often become most persistent and formid- able. Physical Signs.-The extent and nature of the pelvic de- formity produced can only be determined by careful physical exploration. For obvious reasons, this must be conducted with much care. Indeed, if I were satisfied that the uterus did not contain septic products, I should question the wisdom of under- taking a thorough examination in acute pelvic inflammation of any kind. The pain caused by it is usually very great and there is danger of aggravating the disease. A careful digital examina- tion at the onset is usually harmless, however, and when the symptoms become less severe a more thorough examination may be made. In the sub-acute forms of inflammation, as well as in those cases where the formation of pus is suspected, the conditions are very different and call for careful exploration. In the very early stage the vagina will be found hot and dry, with marked tenderness of its vault. This is true in both cellu- litis and peritonitis. Should the cellular tissue be the chief seat of the disease, it is even possible to detect, at the very onset, a soft, edematous spot which indicates the point attacked. This stage is of short duration, and rarely is the examination made early enough to discover it. 416 A TEXT-BOOK OF GYNECOLOGY. After infiltration has taken place the uterus is usually found displaced and fixed. It may be directed backward, forward, laterally, or downward, depending upon the location and the extent of the effusion. To the touch the inflammatory tumor gives a hard, unyielding sensation, and if the effusion surrounds the cervix, it may impinge upon the vaginal fornices to such an extent as almost to conceal the os uteri. By conjoined manipu- lation and percussion the extent of the effusion can be determined. It may dissect up the peritoneum as high as the umbilicus. Examination per rectum will many times afford valuable infor- mation. The posterior surface of the uterus can be reached and the extent of the effusion in this locality determined. If the utero-sacral ligaments are involved they will be felt as two tense bands on either side. Sometimes the inflammation has extended to the perirectal areolar tissue, so that the finger will detect a distinct collar surrounding this organ. Should pus have formed, the tumor will be more or less softened and fluctuation can be detected. The physical changes of pelvic peritonitis vary somewhat from those just given. The general adhesions are usually more extensive, but peritoneal inflammation does not so often give rise to the formation of a distinct tumor. During the early stage any manipulation of the uterus excites intense pain. The hypogastric tenderness is most marked. If the effusion is great it usually gravitates into the posterior cul-de-sac, becomes organized, and can there be felt as an ill-defined mass; or, espe- cially in septic cases, it may remain fluid, being shut off from the general peritoneal cavity by adhesions from above. (Plate II, Fig. 2, e.) The effusion is sometimes great enough to extend above the brim of the pelvis and even as high as the um- bilicus. The uterus is rarely so markedly immobile as in extensive cellular involvement, though in bad cases it is always more or less fixed, and may be completely so. The whole pelvic roof may present a board-like hardness. Complications.—I have already mentioned that irritation of the bladder and the rectum is a frequent symptom of pelvic peri- tonitis and cellulitis. Under the present head it is only ACUTE PELVIC CELLULITIS AND PERITONITIS. 417 necessary to allude to disturbance of these organs for the purpose of again reminding the reader that in those cases not characterized by other decided symptoms of pelvic inflammation we may find, on examination, an inflammatory exudate respon- sible for such disturbance. Acute metritis as a complicating factor has also been dealt with. The remaining conditions to be considered at this time are acute oöphoritis and salpingitis. In my treatment of them here I shall comprise all that I have to say concerning them as distinct acute affections. Let it be remembered that acute metritis and general pelvic inflammation are often due to disease of the appendages. Gon- orrheal salpingitis is a most frequent cause of pelvic peritonitis. On the other hand, metritis and general pelvic inflammation rarely if ever run their course without implicating the append- ages. In perhaps the larger number of cases this occurs without our being able to determine the fact by any special symptoms. In reality, then, acute ovaritis and salpingitis occur as an essential feature of general pelvic inflammation, rather than as a complication. We may, however, suspect involvement of the ovary, if pain and tenderness in the region of the affected organ are marked, particularly if the attacks of pain are attended with nausea and vomiting. It may be possible by conjoined manipulation to get the enlarged and tender organ between the examining fingers; or rectal exploration may reveal the pro- lapsed and adherent ovary between the uterus and the rectum. Acute inflammation of the tube is always associated with that of the ovary. The sequela of inflammation of these organs are very variable. If the ovaries are not too seriously damaged, resolution will ensue upon the subsidence of the general inflammation, or they may remain imbedded in the inflammatory mass. Suppura- tion frequently occurs, calling for their removal. The chronic diseases of the appendages are considered in chapters XLVIII and XLIX. Differentiation.-The various forms of acute inflammation of the pelvis are differentiated, as nearly as it is possible to do so, in the table of comparison given on page 428. The only con- 27 418 A TEXT-BOOK OF GYNECOLOGY. ditions, therefore, calling for consideration at this time are the following:- Pelvic hematocele and extra-uterine gestation; Uterine fibroids; Retro-displacements of the uterus; Carcinomatous infiltration; Accumulated feces. Any of the foregoing conditions may lead to confusion when the resulting tumor resembles that caused by an inflammatory exudate. Pelvic hematocele, from whatever cause, gives rise to symptoms first characterized by shock and collapse. The blood is poured either into the peritoneal cavity or into the underlying cellular tissue, thus forming a tumor. The latter, unlike that of cellulitis, is at first soft, becoming hard after the absorption of serum. If inflammatory symptoms ensue, they follow those of shock and collapse. Extra-uterine gestation is the most frequent cause of pelvic hematocele. Unfortunately, its existence is often unsuspected until rupture occurs. There are no pathognomonic symptoms of this condition. We may suspect it in a patient whose menstrual function has been disturbed or is absent, if a tumor is slowly formed in the region of one broad ligament, and is ac- companied with spasmodic pains in the affected locality. These symptoms are, however, quite as often absent as otherwise. Uterine fibroids are attached to the uterus and, if not adhered, move with it. There is no history of inflammation to account for their presence. The tumor is painless, and instead of dimin- ishing as time goes on, it more often slowly increases in size. In the interstitial and submucous varieties excessive menstruation is a frequent symptom. In the event of adhesions the differen- tiation is sometimes extremely difficult. The unnatural position of the fundus in retro-displacements of the uterus may give rise to uncertainty as to the nature of the tumor in the posterior cul-de-sac. This is especially so if the fundus is bound down by adhesions. Conjoined manipulation will, in the first place, reveal its absence in front; next, by ACUTE PELVIC CELLULITIS AND PERITONITIS. 419 passing the sound, the tumor is penetrated, which is not the case when due to any other cause. In carcinomatous infiltration there may be slight febrile symptoms. The disease almost always begins in the cervix, which will be found indurated and, during the later stages, ulcer- ated. It is insidious in its development, and in due time cachexia supervenes. Accumulated feces ought not to be mistaken for an inflamma- tory exudate, yet, strangely enough, it more than once has been. A fecal tumor pits upon pressure. An examination per rectum will ordinarily suffice to reveal its true character. In all cases of doubt the colon and rectum should be thoroughly emptied either by an enema or a cathartic. Course, Duration, and Sequelae.-No two cases of pelvic peritonitis and cellulitis run exactly the same course, and the duration and sequelæ are most variable. We have seen that pelvic inflammation may exist for an indefinite length of time without giving rise to serious trouble. This, unfortunately, is the exception to the general rule, and usually marked pelvic changes make their presence known in many ways. Pressure symptoms are of frequent occurrence, the location of the result- ing pain depending upon the structures impinged upon. If the great sciatic, the crural, or the external cutaneous nerve is involved, pain is communicated respectively to the posterior surface of the thigh, the dorsum of the foot, or the knee. If the psoas muscle of either side is affected the corresponding limb is flexed or abducted. It may be many weeks and even months before the foot can be put to the floor. Involvement of the bladder and the rectum may continue indefinitely, the dysuria and tenesmus becoming most distressing. The rectum is sometimes so distorted as to mold the feces into ribbon-like bands. Pus may continue to discharge for a long time through either the bladder or the rectum. Amenorrhea, dysmenorrhea, or menorrhagia are frequent sequelæ. In some instances the ovaries are so completely damaged as to destroy entirely their function and menstruation ceases; in other cases, probably the larger number, excessive menstruation results. At least my experience is in keeping with this statement. In removing 420 A TEXT-BOOK OF GYNECOLOGY. appendages damaged by inflammation, menorrhagia has usually been a prominent indication for the operation. Dysmenorrhea, due either to continued inflammation, to distortion of the uterus, or to involvement of the appendages, frequently follows in the train of the disease. It is not uncommon for inflam- matory symptoms to recur at each menstrual period-the result, probably, of an escape of a slight amount of pus at this time from the Fallopian tubes. Sterility, which is a frequent sequel, may be due to any of the causes giving rise to disordered menstruation. Should pus form, the resulting abscess may rupture in any of the directions indicated under the head of pathology. After rupture the abscess may heal and contract, or continue to dis- charge for an unlimited time, or it may involve the cellular tissue of the entire pelvis, communicating externally by several sinuses. Prognosis. This, in severe attacks, should always be guarded. Parturient cases are the most dangerous. In forming a prog- nosis the cause of the inflammation, the vitality of the patient and her environs, the quantity of effusion, and the presence or absence of septic symptoms should be noted. If an abscess forms, this may exhaust the system before healing spontane- ously. Recovery, so far as life is concerned, is the rule, though chronic invalidism only too often results. TREATMENT. The treatment of the various forms of inflammation included in this chapter can best be considered under the following heads: 1. Prophylaxis; 2. Removal of cause if possible after onset; 3. Prevention of effusion of serum; 4. Treatment of symptoms; 5. Absorption and removal of exudates. Prophylaxis.-The various causes enumerated are to be avoided. No accoucheur can do his full duty to his patient without thoroughly mastering the principles of antisepsis. This, in its broadest sense, implies a full knowledge of those methods. ACUTE PELVIC CELLULITIS AND PERITONITIS. 421 having for their object the complete emptying of the uterus. More than this, it implies a familiarity with the evils of pro- longed labor, for we have seen that septic inflammation oftener follows in the train of childbirth when the tissues are injured by long-continued pressure. And last, but not least, it implies. cleanliness on the part of both patient and physician. There will be fewer cases of sepsis following delivery when Credé's method of expressing the placenta is more generally practised. It is a notorious fact that the average physician has not mastered, simple as it is, the technique of this method. By it the uterus is most thoroughly emptied of all débris and clots, and the danger of leaving portions of the membranes behind is reduced to a minimum. In early abortions the physician should not feel at ease so long as any offensive discharge proceeds from the uterus. Proper rest should always be observed after both parturition at term and abortion. The patient should not resume marital relations until involution of all the organs is complete. In non-puerperal cases every precaution should be taken in all operative procedures, no matter how slight, to prevent sepsis. In the event of chronic uterine and periuterine inflammation there is always danger of its becoming acute by operating upon the cervix, or by even introducing the sound. I do not mean to infer that we should refrain from all operations or examinations within the vagina because of the existence of sub-acute or chronic inflammation. I merely wish to caution the student that, when these conditions prevail, he should proceed with care, especially at or near the menstrual period. Removal of Cause. When the inflammation proceeds from the retention of septic matter within the uterus the indications are, clearly, to remove it as speedily as possible and to wash away all shreds and débris with an antiseptic, intra-uterine injec- tion. If particles of membrane are retained the discharge is usu- ally offensive and this condition calls for immediate exploration. The patient should be placed upon her side before a good light, a Sims speculum introduced, and the cervix gently fixed. The uterine cavity should now be thoroughly cleared of all septic pro- ducts by means of a dull wire curette. 422 A TEXT-BOOK OF GYNECOLOGY. Before and after the curetting the cavity should be washed with a hot bichlorid solution (1-10,000). It must not be used stronger than this within the uterus, and great gentleness should be observed. Unless the os is sufficiently large to permit the water to escape at the side of the tube a reflux catheter is neces- sary. After thoroughly douching the parts in the manner described, the operator should apply over the entire surface of the endo- metrium either impure carbolic acid or compound tincture of iodin. I prefer the former unless hemorrhage is troublesome, in which case the iodin will serve both as a hemostatic and an antiseptic. I have more than once seen, after this procedure, the tempera- ture drop in a few hours from 104° or 105°, to normal. Should it remain so, it will not be necessary to repeat the intra-uterine douching. If, on the contrary, it rises again, the douching must be repeated as often as every four, five, or six hours. In those instances in which the temperature drops to normal and remains so, the condition is one of simple septic intoxica- tion, and the system very quickly eliminates the products of chemical decomposition which it has absorbed. This is not the case, however, when the system becomes more profoundly im- pressed, probably because of the entrance and multiplication of germs. Here intra-uterine douching may do good, or it may prove entirely futile. The curette does not always remove all of the germ-infected tissue, and by persistently using the douche the germs may be kept from multiplying and entering the or- ganism; but to accomplish this it must be used at least every four or six hours. If the temperature be not affected by this treatment at the end of twenty-four hours, the douching will probably do no good and may as well be discontinued. The system, in these cases, is surcharged with the septic poison already absorbed, to which the persistent high temperature is due, and which must be contended against by other measures. Prevention of Effusion of Serum.-A chill followed by fever and more or less distress in the pelvic region always calls for complete rest on the part of the patient. She should at once be placed in bed and kept absolutely quiet. If the case is not of ACUTE PELVIC CELLULITIS AND PERITONITIS. 423 septic origin, the aim should be to abort the attack and prevent effusion by measures which, I am firmly convinced, will, if. faithfully carried out, accomplish the desired end in at least a goodly percentage of cases. To accomplish this the indicated remedy, which, in nine cases out of ten, will be either aconite, belladonna, or veratrum viride, is of first importance. Of almost equal importance is the use of the hot vaginal douche, as recom- mended by Emmet. To be of service, however, it must be used in such a way as to bring into action the thermic proper- ties of the water. The vaginal douche can be advantageously supplemented by hot fomentations over the hypogastrium, hot drinks, etc. Treatment of Symptoms.-The management of any form of pelvic inflammation, after it is once inaugurated, requires no little tact and judgment. Absolute rest can be afforded only by the coöperation of a skilled nurse who will anticipate and attend to the patient's every want. The diet should be concentrated and nourishing, with the judicious use of stimulants added in septic cases; and the internal remedy should be selected with much care. Cases of septic origin usually call for one of the following remedies: Arsenicum, lachesis, bromine, or mercurius. The bowels should receive due attention. I cannot agree with some of my confrères that it is a matter of slight impor- tance whether or not the bowels move in these cases for several days. Constipation not only aggravates the existing pelvic inflammation, but, in septic cases, it closes one avenue for the elimination of the poison. The bowels should, therefore, be moved at least every other day by enemata of warm water, to which may be added, in obstinate cases, either ox-gall or gly- cerin. When the tympanites is great there is nothing more useful than a saline cathartic. The relief offered by it is often most decided. • Relapses are of frequent occurrence, and the patient should be kept in bed until the acute symptoms have subsided. There is always danger in getting up so long as the temperature remains above the normal or movement causes local pain and distress. Absorption and Removal of Exudates.-This is often a most difficult task and may require for its accomplishment a 424 A TEXT-BOOK OF GYNECOLOGY. long period of time. Until after the subsidence of all acute symptoms we are compelled to rely almost solely upon the vaginal douche and the internal remedy. The douche, by over- coming congestion and stimulating the lymphatics, accomplishes much good and its value cannot be overestimated. Apis mellifica is often most useful during this stage. As the disease becomes more chronic, other measures are of the greatest utility. The cotton-wool tampon medicated with boro-glycerid and iodin will promote absorption. The medica- ments excite a flow of serum, thus relieving congestion, at the same time stimulating the lymphatics, while the tampon itself exerts sufficient pressure to hasten absorption. Galvanism is a therapeutic resource of the greatest value in the removal of old inflammatory exudates and adhesions within the pelvis. It is simply astonishing to observe with what rapid- ity large inflammatory exudates will often melt away under repeated applications of a current varying from twenty to one hundred milliampères, supplemented, of course, by the other measures recommended. The question of removing encysted serum or pus by opera- tive measures must necessarily depend upon the conditions that exist. It may be given as almost an axiom that encysted non- septic serum, even though large in quantity and easily accessible, does not require operative interference unless the pressure induced by it gives rise to unusual suffering. Nature will ordi- narily care for such an effusion as this. On the other hand, if the evidences of pus are clearly marked, the circumstances are very different, and evacuation is, in the larger number of cases, called for. This may be accomplished when the abscess points into the vagina either by the aspirator, the trocar, or the bistoury. The abscess cavity should be washed out and, if the bistoury has been used, drained. The operative treatment of pelvic abscess is dealt with in detail in the chapter devoted to that subject. Therapeutics. Aconite.-The early congestive stage with anxious expression of face; GREAT RESTLESSNESS, High fever, and rapid pulse; burn- ACUTE PELVIC CELLULITIS AND PERITONITIS. 425 ing, cutting, darting pain in bowels, worse from the slightest pressure; abdomen hot to the touch; intense thirst. Veratrum viride.-Great cerebral congestion; violent nausea and vomiting with cold sweat; heart beats loud and strong with great arterial excitement; respirations are very slow; face flushed; pupils dilated; especially useful in the acute stage of puerperal cellulitis. Belladonna.-Great congestion of the head; strongly pulsating carotid arteries; colicky pains in the bowels; great anxiety; dyspnea; light and noise unbearable; SHOOTING, DARTING, STABBING PAINS, WHICH COME AND GO IN QUICK SUCCESSION.* Bryonia.—Stage of exudation; THE LEAST MOTION AGGRA- ·VATES HER SUFFERINGS; her head aches as if it would split open; stitching, pressing, lancinating pain in the bowels, worse from slightest motion; tongue white and dry; great thirst; bowels con- stipated. Apis.-Stinging, thrusting pain similar to that arising from the sting of a bee; absence of thirst; urine scanty; dyspnea; edema of feet.† Arsenicum.—Sudden sinking of strength; intense internal restlessness; thirst; constant vomiting; burning in bowels; cold, clammy perspiration. Terebinthina.-Excessive distention of the abdomen with weak- ness and prostration; peritonitis resulting from pelvic hema- tocele.‡ Gelsemium.—According to Ludlam, this remedy is especially useful after belladonna, if tardy menstruation is the cause of the congestion; sharp labor-like pains in uterine region extending *"The abdomen, in belladonna, is swollen up like a drum and very sensitive to the touch, so much so that the patient wants all clothing removed."—Farrington. "Uter- ine congestion is manifested, particularly by a violent stinging, fulness, tension, and urg- ing deep in the abdomen and the sexual organs, with which there is often conjoined a dragging, lancinating sensation around the loins "-Hartmann. +"Apis mellifica is indispensable if pelvic cellutitis complicates the case and if we desire to abort the tendency to all forms of pelvic abscess. But it needs to be given in a low form and frequently repeated.”—Ludlam. "The violent drawing, burning pains in the region of the kidneys, and scanty and bloody, and often suppressed urine, with distressing strangury, are excellent addi- tional indications for terebinthina, should they be present."-Southwick. 426 A TEXT-BOOK OF GYNECOLOGY. to back and hips; pulse at first full and bounding, then feeble and thready.* Colocynth.-Violent, cutting, tearing pains, relieved somewhat by pressure; diarrhea and tenesmus of the rectum; frequent tenesmus of the bladder with scanty urine; in the acute stage of pelvic peritonitis with little effusion; pain especially severe in the left ovarian region. Cantharis.-Frequent and almost continual desire to urinate, ineffectual or with cutting, burning pain and passing only a few drops at a time, which are often mixed with blood; burning in the uterine region; urinary symptoms are of the greatest importance in determining upon the selection of this remedy in acute inflam- mation. Mercurius cor.-Purulent exudations; creeping chills; foul breath; vomiting of slime and slimy stool with straining; edema of feet; weakness and emaciation (Lilienthal)†. China. Distention and oppression of the abdomen, especially following great loss of blood; much ringing in the ears; diffi- cult, but painless urination. Calcaria carb.-Subacute and chronic cases in leucophlegmatic constitutions; the feet feel cold and damp; profuse perspiration of the head and upper part of the body; the history of the case shows that the menses have been too profuse and return too often. Hepar sulph.-Particularly indicated to prevent or hasten suppuration; burning, throbbing pain with chilliness. Lachesis. This remedy is especially indicated, according to Guernsey, in pelvic inflammation occurring at the critical age; exacerbation of the soreness after every sleep whether by day or by night; extreme sensitiveness to pressure; cannot even toler- ate the clothes upon the uterine region. ‡ * "The pulse rises, in gelsemium, during the reaction after the chill as far above the normal as it has been below it.”—T. F. Allen. • • +"Inflammation of the peritoneum and effusion into this sac is a frequent feature in poisoning by corrosive sublimate . I have myself the highest esteem for this remedy in peritonitis. I have used it here more frequently than bryonia and with more gratifying results." —Hughes. "In peritonitis lachesis is indicated when the fever still continues and is worse after I P. M. and at night. The slightest touch to the surface of the body is intoler- able.” — Farrington. ACUTE PELVIC CELLULITIS AND PERITONITIS. 427 • Phosphoric acid.-Great distention of the abdomen with marked debility and great indifference to all about her; low fever. Rhus tox.-Puerperal cases worse at night, especially after midnight; restlessness; changing the position affords temporary relief; powerlessness of the lower limbs, she can hardly draw them up; low fever with dry tongue. Hyoscyamus.-Spasmodic symptoms with jerking of the extremities, face, and eyelids; emotional disturbances; typhoid state with delirium; the patient throws off the bedclothes. Iodium.-Implication of mammæ, which become very sore; there is a low cachectic state of the system with feeble pulse. Sulphur.-Weak, faint spells with frequent flushes of heat; papillary eruptions over the body. Sabina. Metritis following menorrhagia or metrorrhagia of clotted and fluid blood, with pain from sacrum or lumbar region to pubes. Silicea.-Constant chilliness followed by fever with violent heat in the head, worse at night; especially useful after suppura- tion with fistulous openings which discharge a large amount of thin, unhealthy pus; profuse, sour, or offensive perspiration at night; headache and nervous symptoms resulting from loss of strength; great constipation; constant and ineffectual desire for stool. Cimicifuga.-Rheumatic women subject to pleurodynia, rheuma- tism, etc.; LUMBAGO; pain and distress in the pelvis with scanty or irregular menstruation; despondency; subacute pelvic peri- tonitis in rheumatic women. Opium.--Cases resulting from fright; flushed face; delirium; soporousness; sleepy but cannot sleep; constant vomiting and belching; complete inactivity of the lower bowel. Arnica.-Pelvic inflammation from traumatism. Consult :-Stramonium, secale, sepia, platina, pulsatilla, kali carb., and conium mac. TABLE COMPARING ACUTE INFLAMMATION OF THE VAGINA, UTERUS AND ANNEXA, AND PERI-UTERINE TISSUES. VAGINITIS. Most frequent cause is gonor- rheal infection; difficult to differentiate specific from non- specific form. Intensity of onset depends upon acuity of symptoms; usually slight chill or chilliness. Febrile symptoms slight. METRITIS AND ENDOMETRITIS. Most frequent cause is sepsis connected with abortion or parturition. In light, non-puerperal cases the initiatory symptoms at onset no more marked than in vagi- nitis; in puerperal cases de- cided chill. Febrile symptoms usually slight in uncomplicated non-septic cases; marked in septic cases. PERITONITIS. When primary, most frequent cause is extension of inflammation from uterus or tubes; imprudence during menstru- ation; gonorrheal extension. Initiatory chill not marked. Febrile symptoms depend upon cause and extent of tissue involved; usually marked, and the pulse is small and wiry. Absence of inflammatory tumor; Absence of inflammatory tumor. Formation of tumor,which is oftener loca- vagina first dry and hot, and then becomes bathed in pus or muco-pus. Thighs not retracted. Thighs not retracted. movable. ted posteriorly or anteriorly; if lateral, usually high up; does not bulge into fornix; hardening of pelvic roof. Retraction of both thighs. Uterus is movable, and not in Uterus is increased in size, and Uterus but slightly movable, and often creased in size. fixed; displaced in any direction, de- pending upon location of effusion. CELLULITIS. Where primary, most frequent cause is connected with operations upon uterus; parturition and abortion. Initiatory chill marked. Febrile symptoms depend upon cause and extent of tissue involved; usually marked, and the pulse is full and bounding. Formation of tumor, which is oftener lateral; at first soft and doughy, then hard, becoming soft again if pus forms. Retraction of one thigh. Uterus more movable than in peritonitis; usually displaced laterally. Pain of a burning character Pain indefinite; augmented by More painful than in cellulitis, and some- Pain depends upon pressure. and low down. moving uterus. No vomiting. times pain is very great. No vomiting if uncomplicated. Vomiting often marked; worse if ovaries Vomiting not so marked. are involved. 428 CHAPTER XXIX. CHRONIC ENDOMETRITIS (CERVICAL AND COR- POREAL); CHRONIC METRITIS (SUBINVO- LUTION; HYPERTROPHY; AREOLAR HYPERPLASIA). For reasons similar to those given in the preceding chapter I deem it entirely logical to include in one chapter the several chronic inflammatory affections of the uterus. They all possess symptoms in common, and the principles of treatment observed in all are much more alike than is the case in the treatment of acute and chronic inflammation of any of the tissues of the uterus. This classification is, therefore, infinitely less confusing to the student than the older one in which the various acute and chronic diseases of the organ are considered seriatim. Then, too, the pathological changes justify the classification adopted, for there is at least an insensible shading of the various forms of chronic inflammation into one another, and, oftentimes, the blending is very distinct. Chronic cervical endometritis, and granular and cystic degeneration of the cervix, represent, in reality, but different stages of one and the same disease. The general symptoms are practically the same in all, and they can be differentiated the one from the other only by physical examination. So-called fungoid degenera- tion of the endometrium likewise represents but a form of corporeal endometritis and should be so dealt with. Again, subinvolution of the uterus, hypertrophy, and areolar hyperplasia are but stages of chronic metritis (although areolar hyperplasia occasionally oc- curs in nulliparous uteri), and are therefore included under that head. CHRONIC CERVICAL ENDOMETRITIS AND GRANULAR AND CYSTIC DEGENERATION OF THE CERVIX. Definition. By the term chronic cervical endometritis is meant an inflammation, chronic in character, of the cervical mu- 429 430 A TEXT-BOOK OF GYNECOLOGY. cous membrane, which extends from the os externum to the os internum. It is the most frequent of all gynecological diseases, and is also known as endo-cervicitis, cervical catarrh, etc. Anatomy.-The surface of the cervical mucous membrane is greatly increased by the so-called arbor vitæ, which are nothing more than folds or ridges of mucous membrane studded with numerous villi and covered with cylindrical and pavement epi- thelium. Large numbers of muciparous glands, known as the follicles of Naboth, are between these folds. It is estimated that in a well-developed virgin cervix there are at least 10,000 Na- FIG. 70. FIG. 71. LACERATION WITH EROSION OF THE CERVIX. (Martin.) EROSION WITH ENLARGEMENT OF FOLLICLES. (Martin.) bothian follicles, and it is from them that the alkaline cervical se- cretion is derived. Pathology. The first step in cervical endometritis is hy- peremia of the Nabothian follicles. They become engorged and elevated, with dilated mouths, which are filled with a secre- tion which is at first alkaline and viscid, like the white of an egg; later it becomes more adhesive and tenacious, being loaded with epithelial cells; finally, it becomes muco-purulent and sometimes tinged with blood. It also becomes exceedingly acrid, disinte- CHRONIC CERVICAL ENDOMETRITIS. 431 grating the epithelial layers of mucous membrane, which leaves the underlying surface exposed (Fig. 71). This is known as abrasion or erosion, and while in the strictest sense of the term it is a form of ulceration, it is too superficial in character to fall properly into that classification. If the disease is arrested at this point the epithelium is restored and the redness disappears. If, instead, it progresses, the mucous membrane proper becomes im- plicated and the papillæ undergo proliferative changes and pro- ject in the form of granules through the abraded tissue. This constitutes granular degeneration (Fig. 72). † Since the papillæ are richly supplied with blood-vessels, the older works describe this condition as "bleeding ulcer" or "cock's-comb granulation." FIG. 72. FISSURED CERVIX WITH GRANULAR MUCOUS MEMBRANE. (Schroeder.) The granulations sometimes increase in size and number until they form a large mass. The hypertrophy of the mucous membrane which attends the disease creates a tenesmus which may give rise, even in virgins, to great eversion. The os externum becomes patulous and the cervical canal greatly distorted. The manner in which this eversion is produced is shown in Fig. 73. If the inflammation is localized in the muciparous follicles it causes the latter to become greatly distended, and finally to burst, thus giving rise to so-called follicular ulceration. Exten- * Dunglison defines an ulcer as a solution of continuity of the soft parts. Accord- ing to the later researches of Ruge and Veit, the epithelium is not entirely destroyed in this condition. +Ruge and Veit say that these villous projections are not hypertrophied papillæ, but new formations. 432 A TEXT-BOOK OF GYNECOLOGY. sive involvement of these follicles constitutes cystic degeneration FIG. 73- b a d ECTROPION OF THE CERVIX. The cervical mucous membrane is hypertrophied as a result of the inflammation and, because of the tenesmus excited, is forced from the cervical canal: (a) represents the normal state and (b), (c) and (d) the successive degrees of ectropion. (Auvard and Devy.) FIG. 74. LACERATION OF THE CERVIX, WITH CYSTIC AND PAPILLARY HYPERPLASIA, SIM- ULATING EPITHELIAL CANCER. (Munde.) of the cervix (Fig. 74.) Instead of the extensive changes here CHRONIC CERVICAL ENDOMETRITIS. 433 shown the enlarged Nabothian glands may assume the shape of polypi. The foregoing changes indicate the several pathological steps leading from simple catarrhal inflammation of the cervical endometrium to extensive granular and cystic degeneration and ulceration. True inflammatory ulceration is very rarely met with. As already indicated, simple catarrhal inflammation is of most frequent occurrence; granular degeneration also occurs with great frequency; while cystic degeneration, though by no means rare, is much more so than the affection last named. In many cases, however, the only evidence of simple endocer- vicitis will be an unnatural discharge proceeding from the cervix. Etiology. The causes are both predisposing and exciting. Under the first head may be included:- The various dyscrasiæ, as scrofulosis, tuberculosis, etc.; Want of fresh air and exercise; Ill-nourishment; Improper dress; Subinvolution. The exciting causes are:— Cervical lacerations; Extension of vaginitis; Excessive coitus; Prevention of conception; Undue exposure, especially during menstruation ; Frequent parturition; Excessive lactation; Intra-uterine stem pessaries. Of these several causes, the various dyscrasia are perhaps the most important. Women of lymphatic temperament, especi- ally blondes, are particularly liable to cervical inflammation; in these subjects there is a peculiar tendency to catarrh of all the mucous membranes of the body. Endocervicitis in this class of patients is usually most obstinate. Cervical catarrh is almost always a complication of subinvolu- tion, and it is frequently associated with corporeal endometritis. Of the exciting causes cervical lacerations are to be ranked of first importance. The laceration, with consequent eversion, ex- 28 434 A TEXT-BOOK OF GYNECOLOGY. poses the lower part of the mucous membrane to friction against the vaginal walls and to irritation during coitus. The various means resorted to for the prevention of conception frequently give rise to cervical catarrh as well as to general pelvic congestion. Cold vaginal injections immediately after intercourse, when all of the sexual organs are unduly flushed with blood, is a most pernicious practice, though but little worse than the use of con- doms, or the practice of withdrawal of the male organ immedi- ately before ejaculation. In fact, any cause that tends to keep up a congestion of the uterus and the pelvic organs is liable in time to induce cervical catarrh, especially in one predisposed to inflammation of the mucous membranes. Symptoms.-The symptomatology depends more upon the type of constitution met with in a given case than upon the extent of the disease. It is a most common thing for the physician to meet with cases of cervical endometritis in which the local evi- dences of the disease are most marked, though the general symptoms may be entirely wanting; whereas, in other cases with but slight disease, the general symptoms are most distress- ing. Some temperaments are much more profoundly affected than others by any lesion, and as regards those of the uterus this is pre-eminently so. Leucorrhea is the most common symptom, and may be the only one attracting the patient's attention. The discharge is at first thick, viscid and albuminous, but as the disease progresses, and especially if villous erosions exist, it becomes muco-puru- lent and not infrequently tinged with blood. In time other symptoms of a more general character may de- velop. The patient complains of an ill-defined, dragging sensa- tion in the pelvis which is made worse when she is on her feet for any length of time. Pain in the back, which is almost .always aggravated at the menstrual period, is of very common occurrence. The stomach is frequently implicated in a reflex way, so that the nutrition becomes impaired and nervous symp- toms develop. Melancholia, occipital and vertical headache, neuralgia in various parts of the body, and hysterical manifesta- tions may follow in the train of mal-nutrition. Disordered menstruation likewise frequently attends endocervi- CHRONIC CERVICAL ENDOMETRITIS. 435 citis. Dysmenorrhea occurs oftener than menorrhagia, though if the corporeal endometrium is also involved, the latter condi- tion may be the most prominent. Pain upon sexual intercourse rarely results unless there exist cervical hyperplasia with the catarrhal condition. In granular and follicular degeneration there may be hemorrhage following intercourse. Other symp- toms, such as constipation, disordered micturition, etc., are not infrequent. Physical Signs.-The extent of the disease can only be determined by local examination. Digital exploration alone is, however, many times uncertain, for should the os not be patulous the finger may not detect anything wrong. The speculum will more accurately determine the exact patho- logical changes. The parts are frequently concealed by the un- natural discharge which is present. By carefully removing this the cervical tissue will be exposed. In simple catarrhal inflam- mation the slight discharge hanging from the cervix may be the only evidence of disease; or the os may be patulous and the mucous membrane everted and congested; or there may be granular or cystic degeneration as shown in Figs. 72 and 74. If the patient has borne children lacerations are usually found and the eversion is often great. I have even seen the eversion in virgins so great as to cause me strongly to suspect for the time the chastity of the patient. This is not of uncommon occurrence, especially if the disease is associated with cel- lulitis, and I strongly emphasize the fact because the condi- tion frequently gives rise to unjust suspicion. A correct decision is so important that I quote in detail the following case from Emmet: * During the spring of 1880 I was consulted by a young, unmarried girl whom I had seen grow up from a child, and whose character was above reproach. I first made a rectal examination with my finger, with the object of avoiding a vaginal one, if the needed information could be obtained. I detected an extensive cellulitis behind the uterus and to the left, but was unable to recognize the exact condition of the uterus, as a mass, very tender on pressure, was felt, which seemed too large for the cervix and not large enough for the uterus. I was surprised to find that this mass was the cervix greatly enlarged in proportion to the size of the uterine body, and that it had the characteristic feel of a laceration. I introduced the speculum, and, to my * " Principles and Practice of Gynecology," 1884, p. 460. 436 A TEXT-BOOK OF GYNECOLOGY. sorrow, I saw the mucous membrane of the canal everted apparently to the internal OS. If I had been placed on the witness stand I could have conscientiously taken an oath that a criminal abortion had been recently performed. As the poor girl got up from the chair the expression of her face was so indicative of all that was pure and innocent that I could ask no questions. During the whole course of my professional life I never watched the progress of another case with such interest. The cellulitis yielded to treatment with unusual rapidity, and to my gratification the everted surfaces rolled in again as the inflammation lessened; the cellulitis at the end of three months had all cleared up and nothing but a virgin os remained." When in doubt, in a case like that recorded by the eminent specialist just quoted, the only absolute test is time and proper treatment. In virgins the parts will ultimately regain their normal appearance; whereas, if lacerations exist, the rents are only made. more prominent by curing the inflammation and hyperplasia. Differentiation.-Chronic cervical endometritis can be posi- tively differentiated from vaginitis only by a specular examina- tion. It is a frequent complication of chronic vaginitis. The symptoms which distinguish it from chronic corporeal endometritis are given in the section devoted to the last-named disease. There is some danger of confounding granular and cystic de- generation, particularly if hyperplasia and lacerations exist, with epithelioma. The induration in epithelioma is much more marked; there is a peculiar hardness about the os; hemorrhage is more easily excited; and the mucous membrane is attached to the subjacent structures. Every now and then cases will be met with where the uncertainty is very great and a section may have to be removed for microscopic examination. Proper treatment rapidly reduces simple hyperplasia with degeneration, which is not the case if the disease be malignant. In the event of ulceration we should determine whether or not the destruction of tissue is due to syphilis. Syphilitic ulcer- ation of the cervix is not a common affection. It will be recog- nized by its yellow, opaque color; by its precipitous borders and depressed surface; and by the rapid development of con- stitutional symptoms. Prognosis. When left unmolested it may continue indefi- nitely, becoming worse and worse as time goes on. treatment will have to be persevered in for weeks, or While even CHRONIC CORPOREAL ENDOMETRITIS. 437 months in cases of long duration, a cure can usually be accom- plished in the end. CHRONIC CORPOREAL ENDOMETRITIS AND UTERINE FUNGOSITIES. The endometrium of the body of the uterus, like that of the cervix, may be the seat of chronic inflammation. When so affected it has been described under the names of chronic corporeal endometritis, internal metritis, uterine leucorrhea, uterine catarrh, etc. As regards its frequency, corporeal endometritis does not occur nearly so often as does cervical endometritis. So good an authority as the late Prof. Byford of Chicago, makes this asser- tion:* "Inflammation limited to the cavity of the body of the uterus is not common, but I am quite sure that I have met with at least two instances." This to me is a most surprising statement to come from one of Prof. Byford's experience, for I am sure that I have many times met with chronic inflammation limited to the corporeal endometrium, or at least not involving the mucous membrane of the cervix. In by far the larger number of cases, however, it occurs in connection with cervical endometritis. Anatomy.-The mucous membrane of the fundus, like that of the cervix, is studded with numberless follicles which are lined with delicate ciliated epithelium, and open into the uterine cavity much as the glands of Lieberkühn open into the intestines. These follicles are long and curling, their closed extremities pro- jecting toward and into the uterine parenchyma, between which and the fundal endometrium there is no areolar tissue. Numer- ous capillaries form a network about their mouths, projecting like villi into them and ramifying between them. They exist in the form of simple and compound glands: the first are un- branched tubes; the second possess several branches. Pathology. As in acute endometritis, the underlying muscular structure is always more or less involved, though the two affec- tions (chronic metritis and endometritis) are sufficiently distinct to warrant separate consideration. The follicles described are the chief seat of the disease, which *" Medical and Surgical Treatment of Women," page 182. 438 A TEXT-BOOK OF GYNECOLOGY. accounts for the exaggerated discharge. The secretion is not only increased, but altered in quality. It is alkaline and thin during the early stage, but in time becomes rust-like and muco- purulent. The changes in the mucous membrane are most variable. In cases of short duration it is merely swollen and congested. Later on granulations may form not unlike those in cervical endometritis. In the more severe cases partial exfoliation of the mucous membrane occurs, and villous proliferations spring up from the subjacent tissue, owing to exaggerated local nutrition. This last condition constitutes the so-called villous fungosities or fungoid degeneration of the endometrium. As time pro- gresses large numbers of the follicles are obliterated and the mucous membrane atrophies; or the openings of the follicles only are obliterated, resulting in distention from the retained secretions. It is claimed by some pathologists that, in cases of long standing, a thin layer of connective tissue, covered by pave- ment instead of cylindrical or ciliated epithelium, replaces the mucous membrane. Causation.-Many of the causes giving rise to cervical en- dometritis may, under favorable conditions, excite fundal endo- metritis, as well. It is only necessary to enumerate, in the disease now under consideration, the following:- Extension of vaginitis and cervicitis; Parturition and abortion; Retention of menstrual discharge; Membranous dysmenorrhea; Injury resulting from the sound, intra-uterine pessaries, etc. ; Exposure during menstruation. Extension of vaginitis and cervicitis to the corporeal endome- trium is of common occurrence, a fact emphasized in dealing with acute endometritis. It is the specific form of vaginitis which is most liable to extend to the endometrium. Parturition and abortion are not infrequently followed by endometritis because of mechanical injury, or because of some of the products of conception being left behind. In criminal abortion the unskillful use of the sound is very apt to lacerate the endometrium in such a way as to set up inflammation. CHRONIC CORPOREAL ENDOMETRITIS. 439 Probably the most important and frequent cause of corporeal endometritis is the retention of menstrual discharge because of some obstruction to its exit. Whatever the nature of the obstruction, the retained blood becomes deteriorated and clotted. This irritates the mucous membrane, giving rise to uterine contractions, and endometritis. The pathology of membranous dysmenorrhea is so uncertain as to make it difficult to determine in a given case whether this affection is the result or the cause of the endometritis. At any rate, more or less endometritis is always associated with this form of painful menstruation. I have in another place dwelt upon the danger of permitting patients to wear the intra-uterine stem while up and about. When these pessaries were more fashionable than now endome- tritis was more common. I never use them except after divul- sion, and always keep the patient in bed until the stem is removed. The careless and indiscriminate use of the uterine sound in the non-pregnant is sometimes responsible for an acute endometritis which may become chronic. If the sound be intelligently used and is clean, there is, however, but little danger of inflammation attending its introduction. This, of course, implies proper ob- servance of the counter indications. Menstrual suppression from exposure always gives rise to more or less congestion of the endometrium, which may, as time goes on, develop into a chronic catarrh. As is well known, acute en- dometritis from whatever cause frequently ends in chronic inflammation. Symptoms.-These, as in endocervicitis, are remarkable for their variableness. In many cases corporeal endometritis of the most decided nature exists indefinitely without giving rise to any trouble other than a leucorrheal discharge. In most instances, however, the general symptoms are sufficiently marked to attract attention to the uterus, though it cannot be said that they are pathognomonic. The most constant symptom is leucorrhea. The discharge is not nearly so tenacious as that from the cervix, though when the cervical endometrium is also involved there is a commingling of 440 A TEXT-BOOK OF GYNECOLOGY. the discharge from both sources. It may be either serous, muco-serous, or muco-purulent in character; or of a brownish, rust-colored tint. The last named quality is very characteristic, though a similar discharge may occur in any disease of the uterus in which there is a slight loss of blood. In the worst cases the discharge consists of almost pure pus. Again in some forms of senile endometritis it is decidedly watery and, when retained, gives rise to that condition known as hydrometra. In cases of long standing it is often most exco- riating, setting up intense pruritus vulvæ. The symptom which in point of frequency comes next is disordered menstruation. The disease is neary always attended by either menorrhagia, dysmenorrhea, or amenorrhea. The menorrhagia is due to hypertrophy of the mucous membrane, and in fungoid degeneration the loss of blood is usually very great. As soon as the connective tissue becomes affected pain is associated with the menorrhagia. Pain also characterizes exfoliation of the endometrium. In atrophy of the mucous membrane the menstrual discharge is lessened in quantity and may cease entirely. Sterility is a frequent, though by no means inevitable, symptom. I have certainly met with cases presenting all the evidences of chronic corporeal endometritis in which conception occurred. If the mucous membrane is much diseased, however, the woman can hardly conceive, for the unnatural discharge is inimical to the life of both the spermatozoa and the ovum. Pain in some form is rarely absent. It is not in any sense pathognomonic, for it is such as may result from any of the chronic inflammatory affections of the uterus. Patients often speak of it as being of a dragging character, and not infrequently it extends down the inner surface of the thighs. It is always made worse by any physical exercise requiring the patient to be on her feet for any length of time. Deep pressure over the hypogastric region will sometimes reveal tenderness of the uterus. There is often a throbbing, burning sensation in the supra-pubic region. The uterus is more or less tender on bi- manual examination, but not nearly so much so as when the disease involves chiefly the muscular structure of the organ. CHRONIC CORPOREAL ENDOMETRITIS. 44I The bowels are usually inactive, and the superadded constipation tends to aggravate the uterine congestion. The urinary function is likewise frequently implicated, the urinary secretion itself pre- senting all of the varying characteristics of so-called "hysterical urine." As the disease progresses the nutrition sometimes becomes markedly affected. The appetite is impaired, there is often nausea with vomiting, and, if flatulency accompanies these symptoms, as it frequently does, pregnancy may be suspected. There is, too, as in pregnancy, a peculiar tendency to pigmentation of the skin, especially on the forehead and abdomen and around the nipples, which adds to the uncertainty of diagnosis. The pigmentary deposits on the face, together with the emaciation and the dark areolæ around the eyes, give to the patient a peculiar expression to which the name facies uterina has been applied. Any or all of the nervous phenomena mentioned under the Hystero-neuroses not infrequently occur. Hysteria, melancholia, neuralgia in any and every part of the body, and even hystero- epilepsy, may develop. Headache is probably the most frequent reflex pain, and it is located, in at least the larger number of cases, at the vertex. Pain in the right hypochondriac region is not an uncommon symptom of chronic endometritis. Physical Signs.-The tenderness of the uterus on conjoined manipulation, the pain arising from passing the uterine probe, the slightly increased length of the uterine cavity, and the character- istic discharge which has been described, are practically all of the physical signs affording any positive information in making a diagnosis. A leucorrhea issuing from the cervix, with absence of discernible cervical disease, is pretty conclusive evidence that it proceeds from the fundus. The only exception to this statement would occur in cases of pyosalpinx drained through the uterus. There is, too, especially in fungoid endometritis, a peculiar tendency to hemorrhage after the introduction of the probe. Differentiation.-The physical signs enumerated will ordin- arily enable the physician to distinguish chronic corporeal endo- metritis, when uncomplicated, from cervical endometritis. When 442 A TEXT-BOOK OF GYNECOLOGY. the two affections exist conjointly it may be difficult to determine that the fundal endometrium is involved. A symptom of some value is the patulousness of the internal os, which nearly always exists when the fundus is implicated. Care should be taken to determine pregnancy when this con- dition is suspected. * Prognosis.—Under the most favorable circumstances, and with all the resources of gynecic art, chronic corporeal endometritis is an exceedingly obstinate affection. Scanzoni affirms that he has never been able to cure a case of several years' duration, and all writers agree that the prognosis, in diseases of long standing, is most sinister. So much depends upon the coöperation of the patient that, without such coöperation, little can be accomplished. If this can be secured I think that the ordinary cases can be not only greatly relieved, but eventually cured. I speak with much more confidence since adding to my armamentarium proper appa- ratus for the intelligent use of intra-uterine galvanism. The most obstinate cases are those of long duration with much enfeeble- ment of the constitution and with bad retro-displacement of the uterus. Proper drainage of the organ, which is all-important, is difficult when flexion exists, and profoundly debilitated patients are usually unable to tolerate measures having for their object the correction of the displacement. CHRONIC METRITIS (SUBINVOLUTION; HYPERTROPHY; AND AREOLAR HYPERPLASIA OF THE UTERUS). General Considerations and Pathology.-Not infrequently the uterus is found upon local examination to be hard, dense, sensitive, and increased in size. This condition is oftener met with in women who have borne children, or who have had one or more miscarriages. For years the peculiar and marked changes giving rise to this unnatural state were supposed to be the result of a chronic parenchymatous inflammation, and the various text-books dealt with it under the name of CHRONIC METRITIS. Some years ago Prof. T. Gaillard Thomas, drawing his deductions from the pathological findings of Klob, Scanzoni, "Diseases of Females," Am. Ed., p. 202. CHRONIC METRITIS. 443 and others, became convinced that chronic inflammation had but little to do in bringing about this peculiar state of the organ. He sums up his conclusions as follows: * “I. The condition ordinarily styled chronic metritis consists in enlargement due to hypergenesis of tissue, especially of its con- nective tissue, which induces nervous irritability and is accom- panied by congestion. “2. Decidedly the most frequent source of this state is inter- ference with involution of the puerperal uterus. A very large proportion of the cases of so-called parenchymatous metritis are really later stages of subinvolution. "3. Areolar hyperplasia is often induced in a uterus which has once undergone the development of pregnancy by displace- ment, endometritis, and other conditions, including persistent hyperemia. ‘4. The same influences may possibly induce it in a nulliparous uterus, most frequently they do so in the neck, but such a result is exceedingly infrequent. "5. However produced, the condition is one of vice of nutri- tion, engendering hyperplasia of the connective tissue as its most striking feature, and, although attended by many signs and symptoms of inflammation, it in no way partakes of the character of that process." Thomas therefore teaches that the term chronic metritis is a misnomer and should be discarded, and that the actual con- dition brought about by the causes enumerated, the most frequent of which being arrested puerperal involution, is hyperplasia rather than hypertrophy of the uterus. He has accordingly proposed the term areolar hyperplasia as one more clearly defining the actual pathological changes which the tissues of the uterus undergo. To him the profession is much indebted for his able and scholarly writings upon the subject. If it be true, as Thomas affirms, that by far "the most frequent cause of this state is interference with involution of the puer- peral uterus," then subinvolution is but the first stage of areolar * Thomas and Mundé, " Diseases of Women " page 316, 1891. † By hypertrophy is meant excessive growth of the elements of tissue already ex- isting; by hyperplasia, the development of new tissue. (Virchow.) 444 A TEXT-BOOK OF GYNECOLOGY. ! hyperplasia (so-called chronic metritis), and should be so con- sidered; and while hyperplasia is undoubtedly the final step in the pathological process which leads up to it, I think that there is clearly an intermediate stage, which is more correctly de- fined, according to the definition of Virchow, by the term hyper- trophy. In proof of this I quote the observations of Finn made at the Institute of Pathological Anatomy in St. Petersburg.* "I. The normal disposition of the single muscular fiber, as well as of the muscular bundle, remains unchanged. “2. The muscular fibers do not change in quality, neither is there fatty degeneration as a pathognomonic sign of the disease. "3. The muscular fibers are always extended in both their length and breadth above their normal standard, but more so in the former direction. "4. The number of fibers is always largely increased. 5. The amount of connective tissue in the latter stage of the disease is always relatively diminished, but absolutely enlarged, so that the increase of bulk of the uterus is mainly caused by the hyperplasia of the muscular fibers, the augmentation of the con- nective tissue influencing it but little.” Klob, on the other hand, says: "The whole uterine connective tissue sometimes proliferates, either without accompanying in- crease of the muscular substance, or, if this does occur, the con- nective tissue predominates to such an extent that the muscular substance is comparatively of not much account." + It is probable, as suggested by Thomas, that Finn made his examinations during the early stages of subinvolution, whereas the uteri examined by Klob were those in which the changes had existed for a long time. In this way only is it possible to reconcile the statements made by pathologists equally dis- tinguished. It seems very strange indeed that later researches bearing upon the subject have not been made. Surely, the dead room furnishes material in abundance, and it is a question which ought not to be difficult to clear up. Are we justified, then, from the data given, in entirely elimi- nating inflammation as a causative factor in the production of the * American Journal of Obstetrics, Vol. 1, p. 264. + Thomas and Mundé, op. cit., p. 310 CHRONIC METRITIS. 445 affection under consideration, which has for its beginning hyper- trophy of tissue and for its ending hyperplasia? I think not. I have elsewhere shown* that three forms of hyperemia are met with viz: active hypertrophic; passive venous or congestive; and inflammatory. The first gives rise to hypertrophy, because of exaggerated local nutrition; in the second and third there is thrown out a fibrino-plastic effusion, which contracts, cuts off the capillary circulation of the parts involved, and becomes organized into a low form of connective tissue. As a result the connec- tive tissue is not only increased from this source, but the resulting irritation gives rise to hypergenesis of that already existing, and in time the muscular structure is largely sup- planted by it. Now, if these views are based upon sound premises, it is not only possible, but exceedingly probable, that acute metritis, after producing the changes described, will merge into a low form of chronic inflammation which may continue in- definitely; and while granting that uteri which have undergone the development of pregnancy are infinitely more liable to take on the changes ending in so-called areolar hyperplasia, I do not believe that nulliparous uteri, the seat of chronic endometri- tis, are exempt from it. That in the vast majority of instances the starting point is subinvolution no one will deny; but let it be remembered that one of the most frequent causes of subinvolu- tion is inflammation, either of the endometrium, the parenchyma, or both; and if we admit the existence of chronic corporeal en- dometritis—and most authorities are agreed that this is not an uncommon affection-we must also admit the frequent involve- ment, to a greater or less extent, of the uterine parenchyma, due to the peculiar anatomy of the parts. If this be true, it seems to me that such inflammation may not only be the primary cause of the hyperplasia, but it may persist as a feature of it. To recapitulate, then, the pathological changes, as I understand them, occur as follows When following parturition or abortion :- I. The existing hypertrophy of both the muscular structures and connective tissue persists for a certain length of time, owing to arrested involution. * v. page 120. 446 A TEXT-BOOK OF GYNECOLOGY. 2. Hypergenesis of the connective tissue, owing to irritation or exaggerated local nutrition, ensues; or, if the subinvoluted uterus is inflamed, a fibrino-plastic effusion is thrown out, which becomes organized. 3. Then follows condensation of the connective tissue thus formed, which contracts and cuts off the capillary circulation, the whole organ becoming hard, dense, and sensitive. When occurring in the non-puerperal :- 1. If from any cause (displacement, excessive coition, obstructed pelvic circulation, etc.) persistent hyperemia is engendered, there results hypertrophy of the uterus because of exaggerated local nutrition. Hypergenesis of the connective tissue is probably in excess of that of the muscular structure. 2. If, on the other hand, the hyperemia be due to inflamma- tion, there is poured into the parenchyma of the organ a fibrino- plastic effusion. This in time, as in the puerperal uterus, becomes a low type of connective tissue, which, added to that resulting from the exaggerated nutrition incident to the inflammatory hyperemia, causes a preponderance of this tissue over the muscular. Secondary contraction and condensation does not differ from that following parturition. Causation. As will be gleaned from a review of the pathology, any condition, state, or cause tending to keep up a persistent hyperemia of the uterus, either because of direct irritation or by interfering with the return of blood from this organ, is liable in time to induce areolar hyperplasia. Such are:— Arrested puerperal involution ; Excessive sexual indulgence; Cardiac, hepatic, pulmonary, and lung disease; Uterine displacements; Neoplasms and abdominal tumors; Habitual constipation; Chlorosis, anemia, or malnutrition from any cause; Ungratified sexual desire; Prevention of conception. In order fully to appreciate the importance of arrested puerperal involution it is necessary to revert to the physiology of the most re- markable, and, to me, most interesting process of normal involution. CHRONIC METRITIS. 447 A normal nulliparous uterus measures in length, from the external os to the peritoneal investment of the fundus, three inches. In the short space of nine months this diameter is increased to nearly fifteen inches, the transverse to ten inches, and the antero-posterior to nine and one-half inches. Or perhaps the increase will be more easily appreciated by stating that the area is increased from sixteen square inches to three hundred and thirty-nine square inches (Levret), and that the weight is increased from a little more than an ounce to twenty-eight ounces. By the processes of involution a uterus of this size should return in from six to eight weeks nearly to its normal size. Retrograde metamorphosis is inaugurated by the pains of labor, which, by cutting off the capillary circulation and thus interfering with nutrition, lead to fatty degeneration of the muscular fibers. The products of this degeneration are absorbed and the size of the uterus is rapidly diminished. In from twenty- one to twenty-eight days nuclei and caudate cells make their appearance, which develop into new muscular fibers. The uterus at the end of eight weeks becomes normal, or nearly so. The conditions interfering with this retrogressive process may be enumerated as follows:— Cervical lacerations; Getting up too soon after delivery; Pelvic inflammation; Retained products of conception ; Non-lactation. The importance of cervical lacerations and injuries cannot be overestimated. If such lacerations, healed kindly, the outcome would be different, but they unfortunately often do not. As a result cicatricial tissue is formed, which not only interferes with the circulation of the uterus, but by squeezing terminal nerve fibers gives rise to reflex symptoms with resulting nervous depression and vice of nutrition. In this way involution is not only arrested, but hypergenesis of tissue, owing to the unnatural and embarrassed circulation, takes place. There is yet another way by which cervical lacerations inter- fere with the return of the uterus to its normal state. Lateral 448 A TEXT-BOOK OF GYNECOLOGY. tears of any great extent approach so closely the folds of the broad ligaments (even extending into them) as to set up in- flammation of the invested cellular tissue. An inflammation thus excited adds greatly to the uterine congestion, as does any form of periuterine inflammation. It is exceedingly diffi- cult to cure a cellulitis of this origin without first repairing the cervix. Non-lactation is a frequent cause of subinvolution. There exists an almost mysterious connection between the mammæ and the uterus. The application of the child to the breast gives rise to uterine contractions which promote involution. Without this stimulus the uterus is apt to remain large. This is one reason why subinvolution more often follows abortion and premature labor. Another, and to my mind quite as potent a cause, is getting up too soon after early abortions. The remaining enumerated causes giving rise to undue con- gestion of the uterus and the pelvic organs are self-explanatory. Varieties.-Hyperplasia uteri may be limited either to the body or the cervix; or it may involve the entire uterus. In hyperplasia of the cervix laceration usually complicates the disease. This must not be confounded with hypertrophic elon- gation of the cervix, a lesion which is elsewhere dealt with. There probably is more or less hyperplasia in hypertrophic elongation, but the deformity produced in the disease now being considered is very different from that of the latter affection. Again, there may be a cirumscribed area of hyperplastic tissue in the uterine wall which simulates a small fibroid. When the hyperplasia is limited to the cervix the distortion is sometimes of the most marked character. I once saw a cervix thus distorted, which was almost as large as the doubled fist, and which nearly filled the entire pelvis. The patient was re- ferred to me by Dr. Geo. W. Bailey of Buchanan, Mich. The uterus was immovably fixed by periuterine inflammation; there was a bad cervical laceration, and, as she was about fifty years of age, I much feared malignancy. Subsequent treatment so reduced the disease as to justify trachelorrhaphy, and an ultimate cure resulted. Malignancy is often suggested by the conditions pres- ent, and much care is necessary in making a diagnosis. CHRONIC METRITIS. 449 The cervix is much more frequently affected than is the body, though involvement of the latter is by no means rare. A Symptoms. These depend somewhat upon the degree of hyperplasia and the part of the uterus affected, but much more upon the complicating lesions. During the early stages of subinvolution, while the tissues are yet soft and vascular, hypersecretion is a prominent symptom. This manifests itself in the form of a profuse leucorrheal dis- charge and the recurrence of menstruation, or at least a uterine hemorrhage, even though the patient nurse her child. If there be granular degeneration of the cervix a slight hemorrhage often follows coition, or is excited by straining at stool. Owing to the increased weight of the organ displacements are common, and the functions of the bladder and the rectum are more or less interfered with. As the disease becomes more chronic, and the stage of hyperplasia is reached, the symptoms are less acute, but, never- theless, marked. The leucorrhea and hemorrhage will be governed by the amount of endometritis existing with the hyperplasia—in fungoid endometritis the hemorrhage may be the one symptom for which the patient consults the physician. As the disease progresses, however, menstruation may become less and less in quantity until finally it ceases entirely. Other symptoms common to both stages are :— Weight and bearing-down sensation within the pelvis, aggra- vated by walking, standing, etc.; Dysmenorrhea; Gastro-intestinal disorders, as nausea, vomiting, capricious appetite, flatulency, constipation, etc.; Pain in the back and loins; Pain and swelling of mammæ, especially just before and during menstruation; Headache; Dyspareunia; Reflex pains in any and every part of the body; Mental depression and hysterical manifestations; Vesical and rectal tenesmus; Sterility. 29 450 A TEXT-BOOK OF GYNECOLOGY. Dyspareunia is much wore common in hyperplasia of the cervix than when the disease is confined to the fundus, though pain on sexual intercourse is sometimes very intense in cor- poreal hyperplasia. It will be observed that there are no subjective symptoms attending the disease that are in any way pathognomonic. The same phenomena may result from chronic cervical or corporeal endometritis, and, indeed, from many other lesions of the pelvis ; or one or all may be absent in a given case. As already sug- gested, the symptoms really depend more upon the compli- cations-lacerations, displacements, endometritis, etc.-than upon the changes in the parenchyma of the uterus. This being so, we are compelled to rely largely upon physical signs for diagnostic purposes. Physical Signs.-In cervical hyperplasia digital examination will reveal the cervix tender and enlarged. The external os is or- dinarily much dilated, especially if there be laceration with ever- sion. The cervix has usually descended so as to rest upon the pelvic floor, and it can be distinctly felt through the rectum, upon which it almost always impinges. It is characterized by a peculiar hardness after the stage of hyperplasia is reached, which strongly suggests malignant infiltration. In corporeal hyperplasia the uterus will be found, upon bimanual examination, enlarged, and unnaturally tender. The sound will show increased depth of the uterine cavity. If the abdominal walls are not too fleshy, it may be possible to deter- mine through them increased thickness of the uterine walls though, in perhaps the majority of cases of uncomplicated hyperplasia, the uterine cavity remains normal as regards length. During the early stages of subinvolution the tissues, instead of being harder than normal, are soft, and the uterus is increased in size in all of its diameters. Differentiation.-There is some danger of confounding the disease under consideration with:- Early pregnancy; Uterine fibroids; Scirrhus of the cervix. Early Pregnancy.—The pregnant uterus is more globular than CHRONIC METRITIS. 451 when the enlargement is due to hyperplasia; it is much softer, and it is often possible to detect, upon conjoined manipulation, a peculiar tenesmus, and sometimes a rhythmical action; it is not tender, and there is usually amenorrhea as well as other signs of pregnancy. The confusion may, nevertheless, be very great, especially if endometritis exist with corporeal hyperplasia, for, with the en- largement of the uterus, there may be also enlargement of the breasts, darkening of the areolæ, nausea, and vomiting, etc. Menstruation rarely ceases in hyperplasia, but it must not be forgotten that occasionally menstruation continues during early pregnancy. Uterine Fibroids.-It is many times utterly impossible to differentiate small fibroids imbedded in the uterine wall from hyperplasia with enlargement. Menorrhagia is usually more marked in the former condition, there is less sensitiveness, and the enlargement is more localized and less uniform. Positive differentiation can only be made by dilating the cervix and exploring with the finger. Scirrhus of the Cervix.-The following comparison will aid the reader in differentiating between areolar hyperplasia of the cervix and scirrhous degeneration:— Areolar Hyperplasia. The cervix feels like dense fibrous tissue. These tissues are softened by proper treatment. The body is often implicated. Tendency to hemorrhage not marked. The mucous membrane moves over sub- jacent tissue. Absence of cachexia. No tendency to break down. Scirrhous Cancer. It feels more like cartilage. They are not so affected. The body is rarely implicated during the early stages. Tendency to hemorrhage marked. The mucous membrane is attached to subjacent tissue. Presence of cachexia. Tendency to break down. It is yet a mooted question as to whether hyperplasia of the cervix ever takes on malignant degeneration. When cervical lacerations complicate the disease most authorities are agreed that, though not of frequent occurrence, such degeneration may occur. Prognosis.-There are few cases of hyperplasia of the body 452 A TEXT-BOOK OF GYNECOLOGY. of the uterus that can be absolutely cured, so far as restoring the parts to their normal condition is concerned. Much relief can, however, in most instances be afforded, and if the patient is approaching the change of life a complete cure may follow the cessation of menstruation. On the other hand, uterine hemor- rhage may continue indefinitely after ovulation ceases, especially if the endometrium is involved. Under the most favorable cir- cumstances much time is required to benefit a case of long- standing corporeal hyperplasia. When the disease is limited to the cervix the prognosis is not so sinister, for the parts can be gotten at and treatment more advantageously applied. When the changes are due to cervical lacerations the most decided improvement usually follows repar- ation of the tears. TREATMENT. General Treatment.-There are certain general measures applicable to all of the various affections included in this chapter. These should be directed, first of all, toward any diathetic taint that may be present, and to the improvement of nutrition by a properly selected diet. Exercise in the open air, short of fatigue, should be prescribed. Sea-bathing, or, if this is not possible, the daily use of the sitz-bath, will accomplish much good in most cases. Massage and the rest cure are sometimes indicated, though, as a general rule, moderate outdoor exercise is to be encouraged. The bowels should be kept regular and the urinary functions looked after. Sexual intercourse, if indulged in at all, should occur at long intervals and in the most natural way. On the whole, it is better for the patient to live absque marito during treatment. In my experience it is exceedingly difficult to cure or benefit any of the diseases under consideration so long as the patient keeps her pelvic organs constantly congested by any one of the various expedients whose object is to prevent conception. Any or all conditions or causes tending to keep up pelvic con- gestion should receive attention. The clothing ought to be suspended from the shoulders instead of constricting the waist and crowding the abdominal organs into the pelvis. TREATMENT OF CHRONIC ENDOMETRITIS AND METRITIS. 453 Measures having for their object the promotion of uterine contraction and the complete emptying of the organ following delivery at term or abortions should be applied. I have, in dealing with acute pelvic inflammation, especially emphasized this point. Local Treatment.-In chronic cervical endometritis the indica- tions to be covered are:- 1. Any cause tending to perpetuate the catarrhal process should be removed. 2. The parts should be kept thoroughly clean. 3. Congestion should be overcome by the intelligent use of the hot douche. 4. Medicaments should be applied to the diseased surface. FIG. 75- FIG. 76. CONOID CERVIX, PINHOLE OS. (Palmer.) DILATED CANAL FROM OBSTRUC- TION OF OS EXTERNUM; LINES FOR INCISION. (Munde.) Of the removable local causes, we have to do with displace- ments, lacerations, distorted cervices, periuterine inflammation, etc. In dealing with cervical lacerations we are hardly justified in operating until the local disease has been overcome or greatly improved; the cervix is then repaired for the purpose of pro- moting its return to a normal state. Pessaries must be used with much circumspection while the endocervicitis is at all severe. It is better in these cases to correct the displacement as nearly as possible by means of the vaginal tampon. 454 A TEXT-BOOK OF GYNECOLOGY. The form of distorted cervix calling for operative interference is well shown in Figs. 75 and 76. It is in such conditions as are there shown that quite extensive disease may continue indefinitely without causing the external os to gape. As a consequence, the discharges are retained, the cervical canal becomes dilated, and treatment is interfered with. To overcome this condition the hard steel dilators (Fig. 44) should be introduced and the os en- larged. I prefer this method to that of gradual dilatation by the hard rubber dilators (Fig. 43). Thomas and Mundé prefer to incise the cervix, as is shown by the vertical lines in Fig. 76. In my experience simple dilatation has been all that is neces- sary. The vaginal douche is useful both for the purpose of cleansing the parts and overcoming congestion by contracting the blood- vessels. I instruct my patient, in dealing with the condition under consideration, to use the douche at least once a day, pre- ferably twice, and always a short time before presenting herself for treatment. In dealing with granular and cystic degeneration it is often necessary to remove the diseased tissue, either with a pair of scissors or with the sharp curette, before much good will come from the use of local medicaments. In cystic degeneration all that may be necessary is to empty all of the cysts by punctur- ing them with the point of a tenotomy knife, forcing out their contents, and applying to their bases nitrate of silver, nitric or chromic acid. Although I have never used the galvano- cautery for this purpose, yet it strikes me as a good way of destroying the cysts. In very extensive degeneration it may be necessary to amputate a portion of the cervix. As regards local medication, I have likewise expressed my views in full in Chapter X. I believe that it will rarely be necessary to resort to the more powerful application of nitric acid, chromic acid, etc., if each case is treated, not in a routine way, but ac- cording to the indications which present themselves. There is, however, one agent not treated of in the chapter referred to, which, in my hands and in the experience of some of my colleagues, has proved most serviceable. I refer to galvanism. Since using it I am confident that I am curing my patients in a much shorter TREATMENT OF CHRONIC ENDOMETRITIS AND METRITIS. 455 time than formerly. I append to this chapter several illustrative cases showing its usefulness and the method of its application in general endometritis and metritis. I will simply state at this time that when the disease is limited to the cervix, negative cauterization, with from ten to seventy-five milliampères, will ordinarily change the condition for the better very quickly. The applications should be made from two to three times a week for at least three or four weeks. By no means do all cases of cervical endometritis require local treatment other than the patient can administer herself by the use of the hot douche and some liquid medicament. I rarely subject a young unmarried woman to a local examination for leucorrhea alone until an effort has been made to cure the discharge by general measures and the more simple local ones just referred to. Chronic Corporeal Endometritis.-This affection is so frequently associated with, and, indeed, so often is the cause of, menorrhagia and other menstrual troubles that I have, in the chapter devoted to uterine hemorrhage, described my method of dealing with it. The persistent use of the vaginal douche, the intra-uterine applications of the compound tincture of iodin and carbolic acid, followed by the boro-glycerid tampon, is the classical method of local treatment, and, it must be confessed, much good often results from this treatment continued for several weeks or months. Galvanism, too, is a most valuable agent, and I rarely resort to the more radical treatment of divulsion and curetting until galvanism has been given a fair trial. Notwithstanding the intelligent and faithful use of these methods, we will every now and then meet with cases little improved by them. This is particularly true when fungoid endometritis exists, and it is in such cases that curetting does so much good. After the cur- etting and the application of the proper medicament (I have found the compound tincture of iodin or the impure carbolic acid sufficiently powerful; Dr. Mundé prefers a 50 per cent. solution of chlorid of zinc), a strip of iodoform gauze, with one end projecting, should be passed into the uterine cavity to keep the walls separated. A tampon is placed against this and the patient put to bed, where she is to remain for a week. Subse- 456 A TEXT-BOOK OF GYNECOLOGY. quent office applications for five or six weeks are usually necessary. * The foregoing measures are heroic, but since we are dealing with a most obstinate affection, heroic measures are imperative. By observing the counter-indications and proper antiseptic pre- cautions there is really but little danger attending the use of the curette, while the good accomplished more than compensates for the enforced confinement. I do not attribute all of the benefit derived from this oper- ation to the curetting alone, for the measures applied promote drainage of the uterine cavity, the importance of which is especially emphasized by Dr. Gil. C. Wylie of New York. I am convinced that the principle of drainage, as applied to the uterine cavity, is a broad one, and applicable to all forms of endometritis. Subinvolution and Areolar Hyperplasia.-The local measures applicable to these conditions do not differ essentially from those recommended for the two forms of endometritis. When we have the management of lying-in cases, we should promote involution, by thoroughly emptying the uterus, and insist upon the patient's remaining in bed until the fundus can no longer be felt above the pubes; we should encourage, unless positive counter-indications prevail, lactation; and, finally, we should advise against the resuming of marital relations until involution of all of the genital organs is complete. Other local measures should be directed toward the removal of those complications upon which the uterine changes in no small degree depend. Such are cervical lacerations, endometritis, granu- lar and cystic degeneration of the cervix, fungoid degeneration of the endometrium, injuries to the pelvic floor, uterine displace- ments, etc. It may be necessary, if the changes in the cervix are very great, to remove a portion of it as is recommended in hypertrophic elongation of this organ. The hot douche, if it does good at all, must be used even more persistently than in cervical and corporeal endometritis. should be continued for fifteen or twenty minutes at a time. It * A 10 per cent. solution of chlorid of zinc and carbolic acid, in glycerin, is a useful application for office work in these cases. TREATMENT OF CHRONIC ENDOMETRITIS AND METRITIS. 457 Local alteratives are to be used as in endometritis, and un- doubtedly do much good. The most useful of all agents is, however, electricity. I do not resort to electro-puncture, as recommended by Apostoli, but use one or the other pole direct within the uterus. If the parts are very vascular and the tissues soft, or if pain is marked, the positive is used direct; if, on the contrary, the tissues are hard and indurated, the negative electrode should be passed into the uterine cavity. If the positive pole be used direct it should be constructed of platinum. I have rarely seen any good come from a current of less than twenty-five milliampères, unless the chief object is to relieve pain, when one of this strength will ordinarily suffice. However, if the patient can tolerate a current of seventy-five or one hundred milliampères so much the better. At least two applications a week should be made. It must, too, be persisted in for weeks or even for months. Illustrative Cases. CASE LX. Corporeal and Cervical Endometritis.—Miss æt. 22, had been under my care off and on for three years, suffering from corporeal and cervical endometritis. She suffered from reflex symptoms too numerous to mention, the one giving her the most distress being a severe pain in the right hip. Menstruation was excessive, and during the menstrual period there was a profuse, purulent leucorrhea, which was very excoriating, and gave rise to an intense pruritus. The lips of the os were eroded, and the uterine cavity measured three inches. The patient would greatly improve under the ordinary methods of treatment, but soon after discontinuing them she would relapse into her former state. I finally resorted to direct, positive galvanization, beginning with twenty-five milliampères and ending with seventy-five. The seances varied in time from one to five minutes, and were repeated twice a week for four weeks. The internal electrode was Martin's flexible platinum instrument, and I was careful to have the metal come in contact with the entire endometrium, including that of the cervix. Improvement followed the first application, and after the eighth I discharged her. The uterus was still somewhat larger than normal, but the discharge had ceased, the erosion was overcome, and the cervix had a normal appearance. The patient im- ⚫proved in every respect, and is now, six months later, quite well. CASE LXI. Areolar Hyperplasia.—Mrs. æt 52. The uterus in this case was hard, dense, and tender, and measured three inches. Menstruation had ceased two years before consulting me. The patient complained of constant pressure and pain in the uterine region. Because of the pain I first used positive galvanization, but after three or four applications the negative pole was used direct. The applications were made twice a week. At the end of eight weeks she reported herself entirely free, not 458 A TEXT-BOOK OF GYNECOLOGY. only from the local pain and distress, but from the nervous and mental symptoms as well, which at the beginning were marked. CASE LXII. Cervical Endometritis.-Miss æt. 19, consulted me for a most distressing dysmenorrhea. I found obstruction at the internal os with a bad chronic cervical catarrh. The catarrh was treated in the usual way and greatly benefited, but the dysmenorrhea persisted. Accordingly, I resorted to forcible divulsion under ether, inserted a cervical plug, and kept the patient in bed for a week. This operation com- pletely relieved the dysmenorrhea, but the cervical catarrh returned worse than before. I then resorted to local negative cauterization with the most happy results. The catarrh was entirely cured by four applications. The foregoing cases are but a few of the many passing under my observation. The applications, in all instances, were followed by the boro-glycerid tampon and sometimes by direct medication with iodin or carbolic acid. The hot douche and the indicated remedy were also faithfully used in all instances. In addition to these, I will quote in full three cases from Massey's “ Electricity in the Diseases of Women.” * CASE LXIII. Chronic Purulent Endometritis of Five Years' Duration. Com- plete Relief after Eight Negative Cauterizations.-E. L., married, aged 37 years, was seen first in private practice early in March, 1888. She had suffered from hemorrhage five years before, which had left her with a constant, abundant leucorrhea of a green- ish-white color and offensive odor. Menstruation was regular, abundant, and attended with considerable pain. Examination showed an eroded os with thickened lips. Uterus two and a half inches, plus, anteflexed, and slightly hypertrophied. At this visit, thirty milliampères, negative, were applied to the endometrium for five minutes. The odor from the discharge was so offensive as to necessitate opening the office windows. March 12th. Discharge clearer and less abundant. Negative cauterization, eighty milliampères, four minutes. March 16th. Electrode introduced with greater ease. Negative cauterization, one hundred milliampères, four minutes. March 18th. Negative cauterization, one hundred milliampères, four minutes. Discharge clearer and much less offensive. March 20th. Negative cauterization, eighty milliampères, three minutes. Her menstrual period followed several days later, normal in amount and duration, and at- tended with less pain than at any time for years. Several similiar applications were made during the next intermenstrual period, when it was noticed that the discharge was much lessened in amount, and entirely free from odor. The second inter- menstrual period was free from discharge of any kind. Eight months later the patient was seen, and stated that she had remained entirely well since. CASE LXIV. Chronic Metritis of Five Years' Duration. Uterus Reduced to Normal Size and Disappearance of Symptoms after Five Applications to Cavity.— Mrs. M. S., aged 38, mother of one child 10 years old. Five years ago had a mis- * Op. cit., second edition. TREATMENT OF CHRONIC ENDOMETRITIS AND METRITIS. 459 carriage, and has been ill ever since. Suffers from pain in the right groin, which is sore and tender to touch. Menstruation every three weeks; flow normal, with severe bearing-down pains. Has a continuous intermenstrual backache and leucor- rhea. Examination November 25, 1889, showed an enlarged and prolapsed uterus, adherent to the right. Manipulation caused considerable pain. Os eroded and exuded muco-purulent matter; cavity three and a half inches. Forty-five milliam- pères, positive, were applied to the cavity for two minutes. December 9th. Soreness and backache better. Positive cauterization of cavity. Forty-five milliampères, one minute. December 27th. Menstrual flow since last treatment, unaccompanied by pain for the first time in five years. Cavity three inches. Positive cauterization, forty-five milliampères, two minutes. December 30th. More pain than usual. Positive cauterization, forty-five milliam- pères, two minutes. January 3, 1890. Uterus in normal position and freely movable, with but slight pain. Shortening and slight thickening in region of broad ligament. Cavity two and a half inches, but some leucorrhea continues. January 17th. Menstruation at third week. Again painless. Leucorrhea slight. Positive cauterization, twenty-five milliampères, two minutes. January 27th. Leucorrhea more watery. Positive cauterization, forty milliam- pères, three minutes. February 10th. Menstrual flow normal and painless. Cavity two and a half inches. No leucorrhea since last period. CASE LXV. Chronic Metritis of Two Years' Duration. Complete Relief After Three Applications.—Mrs. M. H., aged 31, was seen at Howard Hospital in July, 1889. She had had eight children and one miscarriage, the latter two years before, since which she had been ailing. Pain in back, left side, and head, with abun- dant leucorrhea. Walking difficult. Examination: Uterus hypertrophied, os slightly lacerated, cavity three inches, purulent discharge from uterus. Tenderness in both ovarian regions. She was given three negative cauterizations of fifty milliam- pères each at intervals of one week. After the next period she reported com- plete relief of all symptoms, and the cavity was found to be but two and one-half inches. Therapeutics. Hydrastis Canad.-TENACIOUS DISCHARGE; erosion and su- perficial ulceration of the cervix and vagina; great sinking and prostration at the epigastrium, with violent and continued palpita- tion of the heart; leucorrhea, complicated with hepatic derange- ment and constipation.* * "The general condition of the patient will often afford the strongest indication for the use of hydrastis, namely, the cachectic state, the weak muscular powers, the poor digestion, and the obstinate constipation."—Hale. 460 A TEXT-BOOK OF GYNECOLOGY. Calcaria carb.—LEUCOPHLEGMATIC CONSTITUTION; menses too profuse and too often; the feet feel cold and damp; albuminous leucorrhea from the cervical canal with great lassitude and de- bility. "Every current of cool air seems to go through and through the patient.”—Guernsey. Conium mac.-Leucorrhea of a white, acrid mucus, causing a burning or smarting sensation; prolapsus uteri complicated with INDURATION, ulceration, and profuse leucorrhea. "One of the best remedies in induration, especially of a scrofulous nature.” —Lilienthal. Mercurius.-Lancinating, boring, or pressing pain; discharge variable in character, all symptoms worse at night; much perspira- tion, which affords no relief; MOIST TONGUE, often accompanied with intense thirst; gonorrheal or syphilitic complications. Kreasotum.-Leucorrhea of a yellow color, staining linen yellow, with great weakness; exceedingly corroding leucorrhea, causing redness and itching in the vulva; menses too early, too profuse, and too long.* Sepia.-Pain in uterus, which extends from back to abdomen with bearing down; crosses limbs to prevent protrusion of parts; redness, swelling, and itching eruption of labia; great sense of emptiness in pit of stomach. Murex. A feeling as though something were pressing on a sore spot in the pelvis (Betts); thick, green, or bloody leucor- rhea; sexual erethism. Graphites.—Particularly when the ovaries are affected; scanty menses; IRRITABLE SKIN; weakness in the back and small of back when sitting or walking. Borax.-White albuminous leucorrhea; leucorrhea midway between the menstrual periods. Like all of the other secre- tions of borax, the leucorrhea has an unnatural warmth or heat to it."-Farrington. * "The acridity of the leucorrhea marks clearly the divergence of kreosote from sepia, as well as from murex. This led to the employment of the drug in cancerous and other forms of ulceration of the cervix uteri, and we now choose it when there are burning, sensitiveness, and tumefaction of the cervix, with bloody, ichorous dis- charges; sensitiveness to touch or to coitus; and a putridity, which is foreign to the other two remedies."-Farrington. ་ TREATMENT OF CHRONIC ENDOMETRITIS AND METRITIS. 461 A Pulsatilla.-Thin, acrid leucorrhea, or thick, white mucus, most profuse after menses; tensive, cutting pain in uterus, which is very sensitive to touch or to coitus; amenorrhea.* Arsenicum.-Leucorrhea in women of pale, waxy complexion; prostration; acrid, free discharge; vomiting immediately after taking food; amenorrhea. Aurum.-Syphilitic and scrofulous endometritis; induration and prolapsus of the uterus; great nervous weakness with utter despair. Lachesis. She cannot bear any pressure, not even of the clothes, over the uterine region; metritis during the critical age with FLUSHES OF HEAT; sensation as if the pains were ascending toward the chest; aggravation after sleep. Sabina.-Pain from sacrum or lumbar region to pubes; metrorrhagia of clotted and fluid blood.† Secale.-Subinvolution with putrescence of leucorrheal dis- charge; great debility, with tingling in lower extremities. ‡ Caulophyllum.-Insomnia, paraplegia, atony, and relaxed condition of the uterus; hysterical spasms; menses excessive and irregular. Helonias.-Leucorrhea giving rise to intense pruritus, with heat and swelling of the vulva; GREAT DEBILITY; melancholia, with a sensation of weight; soreness and dragging in the uterus. Cimicifuga.-SEVERE PAINS IN THE SMALL OF THE BACK, down the thighs, and through the hips, with heavy pressing down; the patient is nervous, neuralgic, and hyperesthetic, but not so hysterical as the ignatia patient (D. Dyce Brown); sensitive- ness of all of the pelvic organs, especially the ovaries; INSOM- NIA; MELANCHOLIA. *"In simple mucous leucorrhea pulsatilla is often curative; and in dysmenor- rhea, when the little blood which flows is black and coagulated, and when diarrhea is wont to occur at the periods."-Hughes. +"Consentaneous rectal and vesical irritation adds weight to the indications for the choice of sabina in utero-ovarian disorders."-Hughes. “The secale cor. may, perhaps, be the only remedy required in the treatment of subinvolution. I have treated several such cases successfully with it alone. My preference is for the second or third dilution."—Ludlam. 462 A TEXT-BOOK OF GYNECOLOGY. Nux vom.-Violent aching in the hypogastrium, aggravated by pressure and contact; cONSTIPATION; aggravation toward morning. Sulphur.-Vulva excoriates easily; frequent flushes of heat; weak and fainting spells, with strong craving for food. Iodium.-Acute pain in the mammæ, developed by the metritis; emaciation and low cachectic state of the system, with feeble pulse; ATROPHY OF THE MAMMÆ. Kali bich.-Leucorrhea that can be drawn out in long strings, yellow, ropy, stiffening the linen. Consult :-Kali carb., MAGNESIUM MUR., stramonium, kali sulph, rhus tox., nitric acid, phosphorus, and silicea. CHAPTER XXX. INTRA- AND EXTRA-PERITONEAL PELVIC HEMATOCELE. Definition.-An effusion of blood, which becomes organized, either within the pelvic peritoneal cavity or in the subjacent cellular tissue, is called a pelvic hematocele. When the blood is poured into the free peritoneal cavity, it constitutes an intra- peritoneal hematocele; when it finds its way beneath the peri- toneum, usually between the folds of the broad ligaments, it is known as extra-peritoneal. In order to constitute a true hema- tocele in either event it must become encysted. Blood poured into the free peritoneal cavity, which is not shut off by a limit- ing membrane, is better defined by the term intra-peritoneal hemorrhage. The encysted effusions constitute a distinct, morbid condition very different from non-encysted effusions. Certain terms are used to indicate the location of the effu- sion. Thus, if back of the uterus, it is called a retro-uterine hematocele; if in the cellular tissue surrounding this organ, peri- uterine; if in the cellular tissue surrounding the rectum or the vagina, peri-rectal, peri-vaginal, etc. INTRA-PERITONEAL HEMATOCELE. Etiology. The causes of this accident are both predisposing and exciting. The predisposing causes are:- Age of sexual vigor; The various blood affections, as plethora, anemia, and hemophilia; Uterine diseases. The exciting causes are :— Traumatism ; Intra-vaginal and intra-uterine injections; Excessive or intemperate coition ; Obstruction of the Fallopian tubes. 463 464 A TEXT-BOOK OF GYNECOLOGY. A pelvic hematocele rarely occurs before the age of fifteen or after the age of fifty. During the interval between these ages all of the functions pertaining to the sexual organs are active. The sexual relations undoubtedly predispose, both directly and indi- rectly, to the formation of hematocele. Directly, because of the increased congestion of the pelvic organs resulting from the sexual act, and especially from the various means resorted to for the purpose of preventing conception; indirectly, because of the not infrequent occurrence of extra-uterine pregnancy. It is maintained by Lawson Tait that a ruptured extra-uterine preg- nancy cyst is, in nearly all instances, the cause of pelvic hemato- cele. While it is probably a very frequent cause neither the weight of authority nor clinical evidence, justifies so sweeping an assertion. In the several conditions characterized by intravascular pressure there is, of course, a greater tendency to rupture of the vessels in all parts of the body. Such a condition prevails in plethora, and plethoric women, particularly if the hemorrhagic diathesis is a feature of the changed blood state, are liable to have hematocele. Conversely, anemia, chlorosis, and, indeed, all forms of depravity of the blood, predispose to hematocele, notwithstanding the diminished intra-arterial pressure. The explanation here is, that the resistance of the walls of the blood-vessels is weakened; if from any cause a temporary congestion is induced a rupture may occur. The various uterine affections predispose to hematocele be- cause of the increased pelvic congestion to which they usually give rise, and because also of the cervical obstruction which so often results from such affections. The blood, not being able to escape readily from the cervical canal, is retained, the uterus becomes distended, and a reflux through the Fallopian tubes into the pelvic cavity takes place. Traumatism is not an infrequent cause. The accident may result from lifting, straining, kicks, blows, falls, etc. It follows not infre- quently after operations upon the uterus or within the pelvis, though, as a result of oöphorectomy, hemorrhage is oftener effused beneath the peritoneum. Obstruction of the Fallopian tubes, by preventing the entrance INTRA-PERITONEAL HEMATOCELE. 465 of blood into the uterus during menstruation, may divert the hemorrhage through the fimbriated extremities into the perito- neal cavity; hematoceles from this cause are usually small. Sources of the Blood.-The hemorrhage may have its origin from several different sources. Undoubtedly, one of the most frequent is a ruptured extra-uterine pregnancy cyst. This will be referred to again in dealing with that particular ac- cident. It may be derived from the tubes; it is probable that the mucous membrane of the tubes pours out more or less blood in normal menstruation. If, from any cause, it cannot reach the uterine cavity, it takes the direction of least resistance and escapes from the fimbriated extremities of the canals. That this is true is shown by the fact that in many cases of hematocele the tubes are distended with blood. The amount of hemorrhage in these cases is usually not great, and, if the peritoneum is in a perfectly normal condition and the blood not abnormally irrita- ting, the fluid is quickly absorbed and no tumor is formed. The same may be said of hemorrhage from a ruptured Graafian follicle. No great amount of blood ordinarily escapes from this source. Under the head of sterility I have alluded to the improbability of even the majority of extruded ovules finding their way into the Fallopian tubes. The ovule and the slight hemorrhage attending dehiscence of the Graafian follicles escape into the peritoneal cavity. The resulting distress is usually not great, but the frequent attacks of localized peritonitis during menstruation are often due to this cause. Richet particularly emphasizes the importance of varicosis of the utero-ovarian venous plexus as a causative factor in the production of hematocele. This plexus is often unnaturally en- larged, which condition constitutes "varicocele of the female." Virchow affirms that the veins which make up this plexus, when they become varicosed, frequently contain phlebolites, which give rise to ulceration of their walls. Whatever may be the cause of the weakened condition of these veins their rupture gives rise to profuse hemorrhage, for the plexus is a large one. The older authorities taught that a hemorrhage proceeds, not infrequently, from a preëxisting pachyperitonitis. Most modern 30 466 A TEXT-BOOK OF GYNECOLOGY. writers contend that the importance of this condition in the production of hematocele has been exaggerated. Pathology. In nearly all instances when blood finds its way into the free pelvic peritoneal cavity, it gravitates, unless prevented from so doing by previously formed adhesions, into the Douglas cul-de-sac. This is because the cul-de-sac is the most dependent part of the peritoneal cavity. In the event of its obliteration by previous disease, the next most dependent part is the utero- vesical pouch. If the quantity of blood is not great, it is limited FIG. 77- INTRAPERITONEAL HEMATOCELE, The coagulated blood completely surrounds the uterus and covers the superior surface of the bladder and the anterior surface of the rectum. The small intestines are pushed upward. to one or the other of these pouches. When, however, more blood escapes than can be contained in either of these localities, it may fill the entire pelvis, and, indeed, extend as high as the umbilicus. A very large hematocele is shown in Fig. 77. Here the uterus and all of the pelvic organs are embedded in, and surrounded by, the encysted fluid. INTRA-PERITONEAL HEMATOCELE. 467 The contact of the blood with the peritoneum causes the latter to inflame, and a protective lymph is quickly thrown out, which separates the fluid from the intestines and organs above. This neo-membrane at times so closely resembles in appearance the normal peritoneum as to make it difficult to distinguish the one from the other even after the abdomen is opened. It is probable that, because of this fact, intra-peritoneal hematocele has more than once been mistaken for the extra- peritoneal variety. If the amount of blood is not great, and does not surround the uterus, the sac is bounded in front by the posterior wall of that organ; latterly, by the utero-sacral ligaments and walls of the pelvis; and posteriorly, by the rectum and posterior pelvic wall. Frequently the ovaries and tubes adhere to the walls of the sac and are blended with it. Adhesions of the intestines are of common occurrence. The quantity of the effusion is sometimes limited by a pre- existing false membrane. The blood, when it first escapes, is liquid. Its watery por- tions are, however, quickly absorbed, when it becomes semi- liquid and coagulated, and, as time progresses, solid. These are the usual changes. Sometimes it remains semi-liquid or sirupy, and shows no tendency to coagulate. There is usually some septic taint when this is the case. The walls of the sac vary in thickness, at some portions being quite thick, at others so thin as easily to rupture. Fig. 77 shows how great is the distortion of the rectum and the bladder by the pressure of the tumor. The rectum is some- times so impinged upon as to be completely occluded, and the function of defecation is almost always disturbed to a greater or less extent. So, too, is the function of micturition; indeed, in some of the worst cases the pressure upon the urethra may entirely occlude this canal. When the affection has for its cause a ruptured extra-uterine pregnancy cyst, it may be impossible to find any evidences of the fetus after the abdomen is opened, rupture having occurred before it is sufficiently developed to make its detection an easy matter. A careful search will, in most instances, reveal some of the re- 468 A TEXT-BOOK OF GYNECOLOGY. mains of the chorion. It is this difficulty in detecting the evidences of early extra-uterine pregnancies which has led Tait to make the somewhat sweeping assertion already referred to. Symptoms. The onset may be either sudden or gradual. A careful inquiry will often reveal the history of certain premoni- tory symptoms pertaining to the function of menstruation or to the pelvic organs. Menstruation has, perhaps, been more or less disturbed for some time previously to the onset. Some of the signs of salpingitis may have presented; and, in the event of extra-uterine pregnancy, irregular spasmodic pains in the region of one or the other Fallopian tube may have preceded the rup- ture. Gastric reflexes also occur with more or less constancy in extra-uterine pregnancy. While these premonitory symptoms often occur, the reader must not imagine that they invariably do; indeed, in many instances the patient has enjoyed perfect health up to the very time of the effusion. The intensity of the symptoms will depend in large measure upon the quantity of blood effused. The one condition which is more characteristic of hematocele than any other is syncope. This is indicated by the pallor, the feeble and sometimes imper- ceptible pulse, the subnormal temperature, the hiccough, and, in serious cases, nausea and vomiting. Pain may occur simultaneously with the syncope or not until reactionary symptoms have set in. It is due to the peritonitis excited, and to pressure upon the organs and nerves of the pelvis. The patient will locate it in the pelvic or sacral regions, in the bladder, or in the rectum. Sometimes pressure upon the sacral and the crural nerves will cause intense suffering in the lower ex- tremities. The pain does not depend so much upon the size of the tumor as upon the degree of peritonitis excited: if the blood is especially irritating, or if it is contaminated with pus, the result of pre-existing pyosalpinx, a small quantity of fluid will give rise to a great deal of suffering. The local symptoms are very characteristic. There is almost always tenderness over the hypogastric region, and if the blood- tumor is large enough to reach above the pelvic brim, dulness as well. A digital examination will reveal a tumor in some portion of the pelvis, usually back of the uterus; or, in the event of a INTRA-PERITONEAL HEMATOCELE. 469 large effusion impinging upon all of the fornices of the vagina, the uterus will be found completely embedded in it. The tumor is at first soft and fluctuating, but soon acquires a variable con- sistence, and in time, as we have already seen in studying the pathology, becomes hard. There is of course more or less ten- derness within the pelvis. The bimanual examination shows either that the uterus is in the center of the tumor; or, if the tumor is limited to the posterior cul-de-sac, that the uterus is pushed forward, and the cervix carried almost above the reach of the examining finger. A rectal exploration may be impos- sible because of the occlusion of this organ. Much valuable information can, however, ordinarily be obtained by a rectal ex- amination. • The reactionary symptoms following the syncope usually mani- fest themselves within a few hours after the accident. The de- gree of fever is most variable, though in most cases it is quite marked, the temperature ranging from 102° to 105°. It is largely due to the inflammatory symptoms attending the peritoneal ir- ritation. The pulse corresponds to the height of the fever, though for a time it is more compressible than it ordinarily is in peritonitis, because of diminished intra-arterial pressure from the loss of blood. The temperature shows exacerbations and remis- sions, it being usually higher during the day and early part of the night and lower in the morning. The nausea and vomiting likewise depend largely upon the peritoneal involvement; if the peritonitis becomes general, these symptoms are often most dis- tressing. This is true also of tympanites. Sometimes the dis- tention of the bowels is very great, which condition is frequently associated with nausea and vomiting. Tenderness over the ab- domen is likewise a symptom accompanying peritonitis. Progress of the Disease.-In the event of large effusions the course, under the most favorable circumstances, is usually chronic. It is, nevertheless, surprising with what rapidity nature will ab- sorb, when not interfered with, a large intra-peritoneal hematocele. There is, in most instances, a progressive tendency to recovery either by natural absorption or by spontaneous evacuation. Exacerbations are, however, of frequent occurrence. They result either from new effusions taking place from time to time, or from an extension of the peritonitis. A recurrence of the 470 A TEXT-BOOK OF GYNECOLOGY. hemorrhage is more apt to take place in cases of extra-uterine pregnancy, and the patient is never out of danger until the tumor has so far diminished as to preclude the possibility of renewed hemorrhage, or of suppuration. The process of absorption varies greatly in its activity, requiring all the way from two weeks to many months before it is complete. The patient is often unable to walk for some time after assuming the sitting posture. Uterine displacements are frequent sequelæ. Evidences of the tumor often remain permanently in the form of a hard nodule. Signs of Suppuration.-Suppuration may not occur until some time after the inflammatory symptoms have entirely subsided. Its onset is indicated by a decided chill, or a succession of erratic chills, followed by perspiration, fever, tympanites, etc. The tumor, which had previously diminished more or less in size, increases, and in time becomes soft at some point. Unless artificially evacuated, the pus will find its way either into some of the cavities of the pelvis or through the abdominal wall externally. It most frequently escapes into the rectum, which gives rise to more or less proctitis, the pus being blackish and exceedingly fetid. When the abscess discharges into the vagina the point of rupture is indicated by more or less fluctuation. Fortunately, rupture rarely occurs into the peritoneal cavity and almost never into the bladder. After rupture, whatever may be the point of exit, there is a decided relief of the general symptoms and local dis- tress, though, if the discharge continues for an indefinite length of time, it greatly prostrates the patient and she may die from sheer exhaustion; or, as is oftener the case, from pyemia. Diagnosis. The early symptoms of hematocele are almost pathognomonic. The sudden occurrence of shock, followed by the formation of a retro-uterine tumor, which is at first fluid, becoming gradually more or less solid as time progresses, and the succeeding inflammatory symptoms-all point to hematocele. The conditions liable to be confounded with it are- Ruptured pyosalpinx and pelvic abscess; Tumors resulting from pelvic cellulitis or peritonitis; Tumor resulting from extra-uterine pregnancy; Retro-uterine displacements; Ovarian and fibroid tumors. INTRA-PERITONEAL HEMATOCELE, 47I Ruptured pyosalpinx and pelvic abscess give rise to but little syncope. No tumor ensues except as a result of succeeding peritonitis. Pelvic cellulitis and peritonitis give rise to symptoms which occur in a sequence different from that following hematocele. The inflammatory symptoms precede the formation of the tumor. There is no shock and no syncope. The tumor resulting from extra-uterine pregnancy is of slow formation. It is usually located laterally. There is no shock, no syncope, and no inflammatory symptoms previously to rup- ture. Retro-uterine displacements may be complicated by pelvic inflammation. A tumor in the posterior cul-de-sac due to this cause can be penetrated by a sound passed through the cervical canal; the bimanual will show that the fundus is not in front. Small ovarian and fibroid tumors located in the posterior cul- de-sac ought not to be confounded with hematocele. There is an absence of all of the symptoms characteristic of the latter condition, except the presence of the tumor. Careful inquiry into the history of the case, together with a local examination, will usually determine the true condition. Prognosis. Intra-peritoneal hematocele is usually a most serious condition, though, except when due to a ruptured extra- uterine pregnancy cyst, immediate death rarely occurs. There are certain factors which should always be carefully noted in determining the prognosis. The hemorrhagic diathesis greatly complicates matters, for there is a tendency in these cases to frequent recurrences of hemorrhage. When the system is previously depressed by any of the constitutional diseases, the tumor is apt to remain soft and fluctuating; this is always. unfavorable. In the event of suppuration a spontaneous rupture into the rectum is unfortunate, for the resulting abscess will frequently continue to discharge indefinitely because of incom- plete drainage. In perhaps the majority of cases plastic residues about the uterus remain permanently, to which subsequent ill- health can often be traced. Uterine displacements often result from the adhesions left behind and from the changed condition of the pelvic organs. 472 A TEXT-BOOK OF GYNECOLOGY. EXTRA-PERITONEAL HEMATOCELE. Etiology. The same causes responsible for the intra-uterine variety of hematocele are quite as often responsible for an effusion of blood into the subjacent cellular tissue. As already intimated, the accident frequently follows salpingotomies and ovariotomies. It is probable, too, that this form of hematocele is oftener due to extra-uterine pregnancy than is the intra- peritoneal variety. As regards the relative frequency of the two FIG. 78. EXTRA-PERITONEAL HEMATOCELE, The blood is effused into the pelvic cellular tissue, elevating the pelvic peritoneum and pushing the uterus forward and to one side. All but the cervical portion of the uterus is concealed. (Auvard and Devy.) forms, there exists a difference of opinion among the authorities, owing to the fact that intra-peritoneal hematocele is oftener fatal. The older writers, because of this fact, believed the latter to be by all odds the more frequent form. Information obtained by ab- dominal surgery has thrown new light upon the subject. We now know that when the blood is limited by the peritoneum, death rarely if ever occurs. EXTRA-PERITONEAL HEMATOCELE. 473 It is probable, as taught by Tait, that there are many cases of extra-uterine pregnancy which rupture into the folds of the broad ligaments, giving rise to hematocele; if the fetus dies, as it does in the majority of instances, the hematocele is absorbed and recovery follows. Pathological Anatomy.-Some idea of the size of the tumor and the resulting changes can be obtained by referring to Figs. 78 and 79. Fig. 78 represents a vertical section through the center of the pubes and the center of the sacrum; and Fig. 79, a hori- FIG. 79. C.D. EXTRA-PERITONEAL HEMATOCELE. Transverse pelvic section through rectum, uterus, and bladder, showing lateral dis- placement of uterus. The same pathological condition as represented in Fig. 78. zontal section of the same case through the bladder, uterus, and rectum. The blood is effused into the folds of the right broad ligament, and the two folds are distended in such a way as greatly to distort all of the pelvic organs. The effusion in this case implicates the cellular tissue along the sides of the vagina and rectum, and carries the cul-de-sac of Douglas to the bottom of the pelvic floor. If limited to one side the uterus is pushed to the opposite; if both sides are implicated, the tumor is usually 474 A TEXT-BOOK OF GYNECOLOGY. much greater on one side than on the other. The two tumors may unite in front and back of the uterus. In Fig. 78 the fundus of the uterus is pushed so far to one side that in the vertical section the entire organ is left undisturbed. The cervix is seen projecting through the upper part of the vagina. The pressure upon the rectum and bladder is sometimes greater than in the intra-peritoneal variety. These illustrations represent very large effusions; the distortion is correspondingly less when the effu- sion of blood is not great. Symptoms. Owing to the fact that the quantity of effusion is limited by the investing peritoneum, the symptoms are not usually so marked as in the intra-peritoneal variety. The patient may have been in perfect health up to the time of the rupture; if the hematocele is due to a ruptured intra-uterine pregnancy cyst, the symptoms of this affection may or may not have preceded the attack. She is first seized with a pain, more or less acute in character, which is referred to the lower part of the abdomen. Associated with the pain there is usually a certain amount of syncope. The degree of pressure upon the bladder and rectum will depend upon the size and location of the tumor; it may be very great and give rise to the chief distress resulting from the accident. The reactionary symptoms are ordinarily not so marked as in the intra-peritoneal variety. There is less peritonitis, less fever, and less abdominal tenderness. If suppuration ensues, the symptoms do not differ from those attending the disintegration of an intra-peritoneal tumor. Upon practising the bimanual, a tumor will be found in one or both broad ligaments, usually in one only. The uterus, instead of being in the center or to the front of the tumor, as in the intra- peritoneal variety, is pushed to one side. The physical char- acteristics of the tumor do not differ essentially from those of the intra-peritoneal variety, except that it is at first less fluctuating. The subsequent changes are much the same. It is at first soft, becoming more condensed as time progresses, and, in the event of suppuration, again becoming soft. In every other respect the course and duration do not differ materially from intra-peritoneal hematocele. TREATMENT OF PELVIC HEMATOCELE. 475 TREATMENT OF PELVIC HEMATOCELE. The physician, when called upon to treat a case of hemato- cele, should prevent further loss of blood, if it is possible so to do. He should also direct attention to the shock and syncope when these symptoms threaten life. The patient should be placed in bed as quickly as possible, not even waiting to remove the clothing. Cold applications or an ice-bag over the hypogastric region should be at once applied, while heat is applied to the extremities; and, if the shock is at all marked, friction should be resorted to. If the stomach will tolerate it, stimulants should be administered in the ordinary way; if, on the contrary, the stomach is irritable, and nausea and vomiting are persistent, hypodermic injections of brandy or sulphuric ether may be used. The symptoms are ordinarily too urgent to allow the use of vaginal injections, either hot or cold. To obtain the hemostatic effects of heat would require too much time, and it is hardly safe to resort to cold injections because of the shock attending their use. The indicated remedy should be administered internally. In the event of simple oozing of blood, much good may result from its use. If, however, the hemorrhage proceeds from a large vessel, any form of internal medication will be useless. The foregoing indications are to be employed in the early treatment of all cases and all varieties of pelvic hematocele. The subsequent management, after the diagnosis has been made, will depend upon the quantity of hemorrhage effused, the location of the tumor, the pressure symptoms, and the advent of sup- puration. In extra-peritoneal hemorrhage immediate operative procedures are rarely called for. Indeed, the usual outcome of these cases, under expectant treatment, is recovery. In the event of sup- puration, it is, of course, the duty of the physician to treat the case as one of pelvic abscess. A primary operation may be necessary if the effusion be so great as to give rise to intense suffering because of pressure, or if renewed hemorrhages occur from time to time. On the other hand, as long as the case pro- gresses favorably-the tumor gradually becoming smaller, the pressure symptoms growing less and less severe, the peritonitis 476 A TEXT-BOOK OF GYNECOLOGY. disappearing-the physician's duty is clearly to watch for alarm- ing developments, and to avert them if it is within his power to do so. The treatment of intra-peritoneal hematocele is conducted upon entirely different principles. No matter what may be the cause of the effusion-whether the result of extra-uterine pregnancy or of some of the causes enumerated—there is but one thing to do if life is threatened, as it usually is by the quantity of blood poured out, and that is to open the abdomen, seek the bleeding point, and control the hemorrhage by surgical measures. It seems to me that there is but one side to the argument in favor of so doing. It is in thorough harmony with that broad surgical principle which governs the surgeon in the treatment of hemor- rhage proceeding from any torn vessel which is accessible. There is no restricting tissue limiting the quantity of hemorrhage, as in the extra-peritoneal variety. The capacity of the pelvic and abdominal cavities is practically unlimited; and it would be quite as consistent to wait for a severed radial artery to cease bleeding spontaneously, as to stand by with folded hands, while vessels equally large are pouring their contents into the free peritoneal cavity. The technique of abdominal section for this purpose does not differ from that given for extra-uterine pregnancy. When an operation is resorted to for the evacuation of the contents of an hematocele sac, the site of opening will be de- termined by the location of the tumor. In the majority of in- stances the vagina is the channel through which the contents are most easily reached. The relative merits of the vaginal opera- tion and the abdominal have been the subject of no little dis- cussion. Rosenwasser (Annals of Gynecology, September, 1889) decides emphatically in favor of the latter, and in the statistics collected by him the mortality after laparotomy is 9.9 per cent.; whereas after vaginal incision it is 10.5 per cent. He maintains that the danger is not only less in laparotomy, but that the con- valescence is shorter and the chances of a radical cure greater. The other advantages insisted upon by him are: the opportunity afforded to simultaneously remove other lesions that may exist, the possibility of keeping the sac more aseptic, and the ease with which the hemorrhage is controlled. Most operators, notwith- TREATMENT OF PELVIC HEMATOCELE. 477 standing the statistics presented by Rosenwasser, prefer, at least when the tumor points into the vagina, the vaginal operation. Operation. The vagina should be washed with an antiseptic douche and the patient placed in a favorable posture before a good light. The fluid contents of the sac should be first located by a trocar guided by the finger. The opening made by the trocar is enlarged with the scalpel or a pair of scissors. The nozzle of an irrigator is next gently passed into the sac and the contents washed away with a weak carbolic solution. The sac is now carefully packed with strips of iodoform gauze, which will not only control the hemorrhage but will act as an antiseptic as well. If the hemorrhage is at all profuse, the gauze can be left within the cavity for from three to seven days. After its removal a drainage tube should be inserted, through which the cavity is to be daily washed with an antiseptic solution. Care should be taken to keep the free end of the drainage tube closed by means of a tape. The tube can be held in place in the cavity by pack- ing loosely about it strips of iodoform gauze; or a T-drainage tube may be used instead of a straight one. The length of time required for the complete obliteration of the cavity will depend upon its size and the thoroughness of drainage. Usually from one to three weeks elapse before the discharge entirely ceases. The technique of abdominal section for pelvic hematocele does not differ essentially from that given for pelvic abscess. Under all circumstances an attempt should be made to shut off the hema- tocele cavity by stitching the walls of the sac to the abdominal wound. This is not always possible, in which event the sac should be thoroughly washed out, packed with iodoform gauze, and a drainage tube left in the free peritoneal cavity; or, if the contents of the sac are purulent, it may be wise to reclose the sac from above and make a counter opening through the vagina, as has been done by Mundé in one instance. Mundé opened the abdomen, thinking he had to do with an intra- instead of an extra-peritoneal effusion. Pozzi advises, in those instances where the tumor is remote from the posterior cul-de-sac, and where it projects toward the abdominal wall, subperitoneal laparotomy. He makes a long 478 A TEXT-BOOK OF GYNECOLOGY. incision parallel to the crural arch, after which he detaches the peritoneum as far as the tumor and penetrates the latter with- out opening into the peritoneal cavity. He then passes the finger into the cyst, and by combined vaginal and abdominal touch locates a favorable point through which the drainage tube can be passed into the vagina. An opening is made at this point and a cruciform drainage tube introduced. He thus com- bines vaginal with abdominal drainage. Burton speaks very highly of the use of electricity in pro- moting the absorption of hematoceles. He keeps the patient. quietly in bed and uses a galvanic current with large dispersing electrodes over the back and front; or the negative pole direct within the vagina. He begins with a current of ten milliampères, gradually increasing it to one of fifty milliampères. Von Strauch advocates evacuation of the hematic tumor if it does not grow smaller in a month, even though no evidence of suppuration exists. He prefers the vaginal operation to laparo- tomy. Credé, strangely enough, advocates rectal section. Kraske recommends the sacral method. Therapeutics. Hamamelis.-Hematocele with dark, venous blood from uterus; from accidental causes with diffuse, agonizing soreness over whole abdomen. China.-Pulse irregular, flickering, imperceptible; ringing in the ears as of bells; syncope; SKIN COLD AND CLAMMY; un- consciousness. Arnica.-Hemorrhage caused by injury, concussion, etc.; feeling of soreness as from a bruise in the lower abdomen; hemor- rhage associated with internal bleeding, the blood being bright red. Phosphorus.-Hematocele occurring in women subject to frequent and profuse menorrhagia, the blood pouring out freely and then ceasing for a time; pain in left ovarian region and down the inner side of thigh; hemorrhagic diathesis with tend- ency to blood spitting, bleeding from the nose, and hematuria. Millefolium.-Uterine hemorrhage with profuse flow of bright red blood, which is thin; chilliness; congestion of the TREATMENT OF PELVIC HEMATOCELE. 479 head, face, lungs, heart, etc.; patient is violent and irritable, even though much prostrated by the loss of blood. Apis.-Especially useful for promoting absorption; STINGING BURNING PAINS IN THE PELVIS; burning and soreness when urinating; cutting in left ovarian region extending to right. Mercurius. To promote absorption; deep, sore pain in pelvis; dragging in the loins; chilliness, especially in the evening after lying down, which is not relieved by warmth; chilliness alter- nating with heat; PROFUSE PERSPIRATION AT NIGHT WITHOUT RELIEF. Arsenicum.-Anxiety, restlessness, and chilliness; cannot find rest anywhere; changes place continually; emaciation with anxious expression of face; burning or tensive pain in the ovary; suppuration with symptoms of pyemia. Ferrum.-Great erethism of the circulation; alternate red- ness and paleness of the face; very weak; all symptoms worse at night, particularly after midnight. Consult :- Terebinthina, secale, sulphur, kali iod., lachesis, sabina, ipecacuanha, and nitric acid. CHAPTER XXXI. PELVIC ABSCESS. General Considerations.-Suppuration, as is elsewhere indi- cated, occurs not infrequently as a sequel of acute pelvic inflam- mation, especially if the latter is associated with the puerperal state. The predisposing factors tending to prevent resolution in acute inflammation and to favor suppuration are:- Tubercular and scrofulous diatheses; Depravity of the system because of improper food, environ- ment, etc. It occurs much oftener as a sequel of inflammation when the cellular structure is the tissue chiefly involved, but an effusion resulting from pelvic peritonitis occasionally suppurates, espe- cially in septic cases. Abscess of the Fallopian tubes (pyo- salpinx) and abscess of the ovaries are more appropriately dealt with in the chapter devoted to the diseases of the appendages; and suppuration resulting from caries of the bones of the pelvis and spine, while constituting a form of pelvic abscess, is a sur- gical rather than a gynecological affection, and is not, therefore, included in the following description. It should, nevertheless, not be forgotten that pus having its origin in the lesions speci- fied may give rise, secondarily, to acute inflammation of the peritoneum and cellular tissue, which in turn may result in abscess. This is especially true of pyosalpinx. • Pelvic hematocele, from whatever cause, may likewise end in suppuration. The abscess cavity is not necessarily in contact with the uterus, for the periuterine inflammation may involve remote lym- phatic glands, giving rise to inflammation and suppuration at distant parts; or, in cellulitis, the inflammation may extend to distant parts by continuity. In the majority of instances the seat of suppuration is primarily located between the folds of one or the other broad ligament, but if the accumulation of pus is very 480 PELVIC ABSCESS. 481 great it may burrow in any direction and to almost any extent. Skene says:* * "I have seen three cases in which pus from an abscess in the broad ligament burrowed outward to the iliac fossa, and then extended upward to the diaphragm, and in one it opened through the lung into the large bronchial tube." Pathology.-Pus within the pelvis may remain indefinitely without escaping. However, it usually makes its exit in order of frequency as follows: from above Poupart's ligament; into the rectum, vagina, or bladder; at the anus, or through the saphenous openings. Rarely does rupture occur into the peritoneal cavity, though it may. The encapsulating wall does not differ essentially from chronic abscesses elsewhere. As time goes on the transudation products are transformed into connective tissue of greater or less thick- ness, which constitutes the abscess wall. The interior of the sac thus formed is made up of villous or granular eminences, which consist of "loops of blood-vessels buried in transudation corpuscles." (Agnew.) The leucocytes which give rise to the pus are chiefly derived from these vessels, though in certain localities they are produced in limited numbers by the connective tissue. Pus, after it is once formed, burrows in the direction of the least resistance, and the tissues which exert the greatest resist- ance are the planes of fascia. The size of the abscess is, there- fore, limited only by the fascial attachments, and, as we have seen in the cases cited by Skene, it may dissect up the fascia and peritoneum as high as the diaphragm. In peritoneal abscesses the effusion may surround a tube distended with pus so that, in the event of suppuration, there is a small accumulation of pus within a greater, the former remaining after the latter is evacu- ated. After evacuation the cavity may gradually cease to discharge and the abscess heal; or it may continue to discharge indefi- nitely. The obliteration, when it occurs, is due to the formation of granulation tissue and to the adhesion of opposing surfaces. Obliteration is impossible without complete drainage, and if the *❝ Diseases of Women," 1889, p. 557. 1 31 482 A TEXT-BOOK OF GYNECOLOGY. opening is small, sinuous, or unfavorably located, drainage may be imperfect. Should the abscess empty itself into the intestinal canal or the bladder it is liable to contamination by fecal matter or urine. This may keep up the suppurative process indefinitely, and in due time the entire pelvis may become honeycombed. Symptoms.-The affection, whatever its nature, giving rise to suppuration, will be attended by symptoms peculiar to itself. In pre-existing inflammation we shall be confronted by an inflammatory history; or should the primary cause which is to result in suppuration be a hematocele, or an extra-uterine pregnancy, there will usually be a history of shock and collapse, followed by inflammation. A chill, in most instances, marks the beginning of suppuration. It may be indistinct, but the patient will at least complain of chilliness. This is followed by fever, sweating, and prostration. There is often a throbbing sensation at the seat of suppuration. The pressure symptoms will depend upon the site of the tumor-if the rectum or bladder is impli- cated the functions of one or both are disturbed. Pressure upon the vessels and nerves extending to the lower limbs may not only give rise to much pain, but, by retarding the return of venous blood, to great edema as well. As the disease progresses symptoms of pyemia, from absorption of pus, often become marked. The foregoing is the usual history of the formation of pus within the pelvis. Symptoms of suppuration may, however, be entirely wanting. In certain cases there will be, perhaps, a history of pelvic inflammation, and for some reason the patient does not convalesce as she should. A local examination in these cases frequently shows that, instead of becoming absorbed, the inflammatory tumor remains unchanged, or possibly has increased in size. Indeed, it may be that it has already undergone disin- tegration and there is a large quantity of pus present, as is evidenced by fluctuation, without serious systemic disturbance. Such an accumulation as this is known as a cold abscess, and occurs oftener in asthenic patients. When the pus is limited to the tube or ovaries entire absence of chill, fever, etc., is not uncommon. PELVIC ABSCESS. 483 On the other hand, a small accumulation of purulent matter deep in the pelvis, with no evidences of fluctuation or softening, may give rise to much general distress. Fluctuation is very often inappreciable in intra-peritoneal abscesses, though soft spots can usually be detected per vaginam. Differentiation.-We are called upon to distinguish pelvic abscess from the following:- Nephric and perinephric abscess; Distention of the Fallopian tubes; Hematocele ; Extra-uterine pregnancy; Ovarian abscess. Nephric and Perinephric Abscess.-These affections rarely give rise to an abscess large enough to extend into the pelvis, though I have seen, in consultation with Dr. W. A. Farnsworth of Petosky, such a case. A vaginal examination will demonstrate that the abscess does not originate in the pelvis. The most fre- quent cause of renal abscesses is an injury, the result of a blow or other forms of traumatism, or a calculus. It may follow the administration of cantharides or turpentine. Perinephric abscess, while occasionally an idiopathic disease, is in most cases a sequence of suppuration of the kidney itself. When the dis- tention is at all marked there is discoloration and tenderness over the corresponding lumbar region. The lumbar muscles are fixed, tense, and brawny. Finally, an examination of the urine will usually reveal the presence of pus, or other abnor- malities of this secretion. Distention of the Fallopian Tubes.- It is often impossible to detect slight distention of the tubes. A tumor from this cause is irregular or ovoid in shape, and usually finds its way into the retro-uterine space. It is painless in hydrosalpinx, but palpa- tion gives rise to pain in hemato- and pyosalpinx. Hematocele.-The classical symptoms of this accident, from whatever cause, are shock and collapse, followed by the sudden formation of a tumor. Inflammatory symptoms sooner or later ensue. Extra-uterine Pregnancy.-Before rupture there is a unilateral and obscurely cystic tumor in the region of one of the Fallopian 484 A TEXT-BOOK OF GYNECOLOGY. tubes (in most instances the primary seat is the Fallopian tube). Some of the usual signs of pregnancy may be present, though not infrequently the condition is unsuspected previously to rupture. Ovarian Abscess.-A suppurating ovary is rarely larger than a hen's egg; it is very tender on pressure and lies on one or the other side of the recto-uterine pouch, to which it is usually at- tached by adhesions. It may be obscurely fluctuating. Prognosis. In considering the prognosis there are many points to be noted. The course and duration will depend upon the size of the abscess, the character of its contents, its location, and the nature of its opening, or openings. As regards the life of the patient much will depend upon her vitality and powers of endurance. Then, too, recovery may be retarded by those constitutional taints-scrofulosis, tuberculosis, syphilis, etc. -which always tend to perpetuate the suppurative process in whatever part of the body it occurs. While spontaneous cures often result, it must be confessed that, owing to the inaccessi- bility of the parts, the condition is one to be dreaded. Modern surgery, thanks to Lawson Tait, has, however, made it possible to cure quickly many cases that formerly dragged on until the patient died from sheer exhaustion. Treatment.-As soon as suppuration is suspected the strength of the patient should be sustained by nourishing and concentrated food, free ventilation, etc. The judicious use of stimulants is often beneficial. Hepar sulphur, silicea, arsenicum, and mercurius are the classical remedies in suppuration, and are to be used both for the purpose of aborting and promoting the suppurative process. As regards the surgical treatment there is the greatest diversity of opinion. A review of the literature of the last ten years bearing upon the subject is most interesting. As a rule, the older authors are conservative, whereas the younger men, with few exceptions, teach, with Lawson Tait, that pus within the pelvic cavity is always a source of danger and should not be permitted to make its exit spontaneously. I fully agree with the latter teaching. To me it seems quite as illogical to permit pent-up pus within the pelvis to make its own exit PELVIC ABSCESS. 485 through a route often as circuitous as it is dangerous, as to permit pus within the pleural cavity to take care of itself. I am speaking now of those large accumulations of purulent matter where there is no uncertainty regarding the diagnosis. In the smaller accumulations deep within the pelvis, or confined to the Fallopian tubes, the diagnosis may be uncertain, and an exception to the broad surgical principle of early evacuation, which applies to abscesses in general, may have to be made.* I desire to quote, somewhat in detail, from Lawson Tait. He says: "I had been (previous to 1879), therefore, continually on the lookout for some means of dealing with pelvic abscesses which would bring them as satisfactorily within our means of treatment as are collections of matter in most other parts of the body. This has been furnished by the wide, free, and successful application of abdominal section for the treatment of pelvic and abdominal tumors, and I am now able to give a list of thirty-eight cases, which include the whole of my experi- ence in the novel proceeding, and in which success has been obtained far surpassing anything I have yet seen or heard of. In this compari- son, I am, of course, excluding those cases where pointing of the abscess in the vagina is evident at an early stage of the case, but even in these the recovery has always been, in my experience, more pro- tracted than in the six now to be narrated. In addition to this list, there are about twenty others in which I have operated from above, but without opening the peritoneal cavity. These, of course, under the definition of abdominal section I have adopted, are not to be in- cluded in the present list; but in every one recovery and cure has been obtained. Fifty-eight consecutive recoveries, prompt and per- manent, in such a grave condition, constitute a result of a most satis- factory kind." It will be seen by the foregoing that Tait does not prac- tise opening the abdomen when the abscess points toward the vagina; nor does he open into the peritoneal cavity when it is possible to reach the abscess through the abdominal walls with- *"It may be laid down as a general rule that pus is to be removed as soon as it is formed. In cases of acute abscess this rule may be considered very nearly absolute. We have now at our disposal the means by which the serious complications that were formerly met with as a result of putrefactive changes may be avoided, and the with- drawal of pus has a very beneficial effect in abating the severity of acute inflammatory processes."-Howard Marsh, Intern. Encyc. of Surgery," vol. ii, p. 268. † Op. cit., p. 332. 486 A TEXT-BOOK OF GYNECOLOGY. out so doing. As I understand his teaching, he reserves abdom- inal section, when suppuration is evident, for the class of cases in which there is no tendency for the abscess to open either into the vagina or outwardly through the abdominal wall; or in which it has spontaneously opened, but for some reason continues to discharge indefinitely. That abdominal section has a wide range of application in these two classes of cases I think there can be no doubt. By far the larger number of cases, however, calling for abdom- inal section previously to the discharge of pus through some one of the usual channels, are those in which the abscess is the result of a ruptured ectopic pregnancy cyst. These cases mani- fest a greater tendency to remain quiescent—at least they do not point as quickly as do inflammatory abscesses-and the retention of pus will often give rise to much distress, both local and gen- eral, before a soft spot is felt either from above or below. I maintain that in cases of the kind it is no more dangerous to open the abdomen, empty the abscess of its contents, and stitch the abscess wall to the abdominal wound, through which it can be thoroughly drained and cleaned, than it is to reach the pus cavity through the vagina or rectum; and it is certainly infinitely more satisfactory to both physician and patient. We should, then, in all instances open the abscess through the vagina or abdominal wall when nature clearly indicates these points of exit, reserving abdominal section for the class of cases which cannot be healed by more conservative measures. Just when pus should be evacuated in pelvic suppuration will necessarily depend upon circumstances, for, as insisted upon by Thomas, every case is a law unto itself. As a general rule a reasonable delay is wise. It enables the physician to determine positively that suppuration has taken place, and in the event of several suppurating foci the smaller cavities will coalesce into one. Again, by waiting until the point of exit is indicated, ad- hesions will have formed, so that there is not so much danger of opening into the peritoneal cavity. It may be impossible to de- tect small collections of pus deep in the pelvis, and it would be extremely hazardous to cut into pelvic tissue through the vagina for any great depth for the purpose of reaching such collections. PELVIC ABSCESS. 487 The most obstinate cases of pelvic abscess with which I have had to deal have been those opening into the rectum. Hence if it is possible to reach the pus through the vagina or abdominal wall, it is best to do so.* The operation is performed through the vagina in the follow- ing manner: The vagina is previously made as aseptic as is possible by a 1: 3000 bichlorid douche. The patient is then anesthetized, placed before a good light in Sims' posture, when the vagina is again thoroughly washed with bichlorid. If the point of fluctuation is prominent an incision may be made at once, either with the scalpel or with scissors. Care must be observed not to injure the large vessels, ureters, bladder, or rec- tum. The normal relationship of the parts is usually so altered as to make it wise first to introduce an aspirator, or an exploring needle. After the cavity has been located by the needle Mundé recommends, for the purpose of enlarging the opening, a pair of sharp-pointed scissors which are pushed into the cavity, the needle serving as a guide; the blades are then separated, when the pus will gush forth. The opening can be further enlarged with- out injuring the parts by the method of Hilton, which consists of the introduction and withdrawal of some blunt expanding instrument—an ordinary pair of catch forceps, or a uterine dila- tor. After the evacuation, the cavity is washed with a weak solution of bichlorid (1: 10,000); or, if there is very much fetor, with a solution of permanganate of potash. The finger should be carried into the sac and all sulci freely broken down. If the granulations are marked they should be destroyed, either with the finger nail or a blunt curette. The abscess cavity is again washed, and, if the parts are readily accessible, the tincture of iodin may be applied to the pyogenic membrane. A rubber drainage tube is then introduced, through which the cavity can be irrigated several times a day with a weak permanganate solu- tion. The tube may be held in place by loosely packing the vagina with iodoform gauze. It is gradually withdrawn as the abscess closes, and, finally, entirely removed. * Segond recommends vaginal hysterectomy for pelvic suppuration, and Terrillon trephines the pelvis at the most dependent part of the abscess.-Annual of Universal Medical Sciences, 1892. 488 A TEXT-BOOK OF GYNECOLOGY. Careful watching is required during the healing process. The parts must be kept absolutely sweet and clean, and the opening should not be permitted to close until the sac is entirely obliter- ated. It may be kept open for a few days after the tube is re- moved by passing through it a strip of gauze.* Closure of the Sac and Treatment of Sinuses.-Before abdominal section is resorted to, various expedients are recom- mended for this purpose. If the abscess has opened externally and the sinus is sufficiently large to afford free drainage, an attempt may be made to close the sac by keeping it thoroughly clean and injecting it twice or three times a week with tincture of iodin. Failing in this, the opening should be enlarged, and, if possible, the sac packed with iodoform gauze. The same measures may be tried from below if the abscess has opened into the vagina, and, in a limited number of cases, a cure can be accomplished. When, however, an abscess has opened ex- ternally and continues to discharge indefinitely in spite of all efforts to heal it from above, a counter opening should be made through the vagina. This may be accomplished by passing a strong probe through the external sinus and causing its tip to im- pinge against one of the vaginal fornices. This is cut down upon and, if possible, a perforated rubber tube is drawn from above through the opening thus made into the vagina. The parts can now be thoroughly washed and injected, and the healing pro- moted. The tube is to be gradually drawn into the vagina as the sac closes from above. In the event of fecal contamination care must be observed in * Dr. G. H. Lyman has placed on record (Trans. Am. Gyn. Soc., vol. vi), seven- teen cases of pelvic abscess treated by the aspirator. The results were as follows: Io cures; 4 not benefited; 2 injured; I improved only. The cavity was simply emptied and left without being washed or injected. In commenting upon these re- sults Maury (“ Am. Sys. of Gyn.,” vol. 1, p. 731) justly says: “The results reported are probably too favorable, for the following reasons: one of these cases, as shown by the report, was discharged from the hospital while remnants of exudation were still recognized within the pelvis. Some remained only a few days after the operation, one being discharged five days after aspiration, another thirteen, another fourteen days. The report cannot, therefore, be considered conclusive in regard to the ques- tion of cure." Personally, I use the aspirator in these cases for diagnostic purposes only. PELVIC ABSCESS. 489 making this counter opening. In Case LXVI, the probe passed into the intestine instead of into the abscess, and, had I cut down upon the probe through the vagina, I would have created an entero-vaginal fistula. Cases Illustrating Technique of Abdominal Section. CASE LXVI.—Pelvic Abscess and Fecal Fistula following Laparotomy Cured by Abdominal Section.-Patient æt. 28, married, and referred to me by Dr. A. B. Cornell of Kalamazoo. A large abscess followed an abdominal section made for the purpose of removing a suppurating dermoid cyst of the right side and a pyosalpinx of the left. The operation was a most difficult one, the numerous adhesions necessitating the appli- cation of many ligatures within the abdomen. The patient rallied from the primary operation, and for the first two weeks did remarkably well. Owing to the large quantity of pus which had escaped into the peritoneal cavity, the drainage tube was not removed until the end of the fourth day. As a result, a sinuous tract was left which, instead of healing, continued to discharge pus, and this so contaminated the abdominal wound that a parietal abscess formed. Notwithstanding these several complications, the patient continued to gain in strength and in four weeks was up and about. The sinus continued, however, to discharge variable quantities of pus, and evidently there was a large pus-cavity on the right side extending nearly to the umbilicus. At the end of six weeks chloroform was given, the sinus enlarged, and an effort made to carry a drainage tube to its bottom, but owing to the pain excited by the tube the patient could not tolerate it. At the end of twelve weeks the discharge had diminished but little, and further exploration seemed imperative. Accordingly, on April 21st preparations for any emergency were made, and the abdomen reopened. The sinus led to the base of the right broad ligament down to the colon, and the accumulation of pus had dissected up what was left of the posterior layer of the right ligament, which, together with the peritoneal investment, formed the abscess wall. At the very bottom of the abscess two ligatures were found which had failed to become encysted. This was undoubtedly the secret of the persistent discharge, and in due time the ligatures would probably have found their way to the surface. The next step in the operation was to stitch the abscess wall to the lower angle of the abdominal wound. A rubber drainage tube was carried to the bottom of the abscess cavity and a glass tube into the Douglas pouch, after which the abdominal cavity was washed and the abdomen closed in the usual way. The patient again quickly rallied, and promised a speedy convalescence, when on the fifth day she began to have a fecal discharge through the sinus leading to the abscess. This discharge increased in quantity for ten days, notwithstanding the fact that the bowels were moved every other day by the aid of enemata. It then began to decrease, but fecal contamination prevented the abscess from healing entirely, and, conversely, the pus so contaminated the fecal opening as to prevent its spontaneous closure. A probe passed from above would insinuate itself into the bowel instead of into the abscess cavity, and I therefore did not dare to make a counter vaginal open- ing. Various expedients were tried during the next twelve months to cure the abscess and close the fecal fistula, but in vain. I finally made an extensive dissection of the cicatrix, carefully removed the adhered intestine from the abdominal wall, and closed the opening into it by a series of Lambert sutures. I then passed a drainage tube into the abscess and closed the abdominal wound. On the fourth day fecal matter again 490 A TEXT-BOOK OF GYNECOLOGY. escaped externally, but it gradually grew less in quantity, and in about two months ceased entirely. A small pin-head opening persisted for about two months longer, but finally healed perfectly. The discharging sinus closed very quickly after the fecal matter was kept out of it. The patient is now (twelve months later) perfectly well. CASE LXVII.—Abscess of the Left Ovary and Broad Ligament following Puer- peral Cellulitis and Peritonitis; Laparatomy; Recovery.—Mrs. æt. 28, mar- ried; patient of Dr. D. M. Nottingham's, of Lansing. She presented herself at my clinic on May 23, 1887, and gave the following history: During her eleven years of marriage she had been twice pregnant, the first pregnancy resulting in a miscar- riage at the seventh month because of a strain. Her second child was born thirteen months later, from the birth of which she dates her present trouble. She did not get up well from this confinement. When her baby was four weeks old she was taken with a severe attack of pelvic inflammation, which continued for two months. She fin- ally recovered, and for the following three or four years was fairly, though not entirely, well. She then had another severe attack of inflammation, brought on by undue ex- posure during the menstrual period, and for the succeeding three years suffered con- stantly from pressure pains in and about the pelvis. Following this she was stricken with typhoid fever (September, 1886), since which time she has had most excruciating pain in the pelvis, especially in the left ovarian region, which is of a burning, stinging character. There is also a sharp, cutting pain in the corresponding hip and down the limbs. Excessive menstruation, occurring at first every six weeks, dates from the birth of her last child; but the intervals gradually grew shorter until the inter-men- strual period was but ten days. The flow was always attended by much pain, which began several days before its onset and gradually increased in severity. The patient upon coming to the hospital was almost bloodless from the excessive menstrual discharge. She had been compelled to remain in bed almost constantly since her last illness in September. I found, upon making a local examination, the pelvic organs all matted together, as a result of the previous inflammatory attacks. There was much tenderness, especially on the left side; the uterus was retroflexed and per- fectly immobile; the roof of the pelvis was as unyielding as a board. I could detect no evidence of fluctuation, but was positive that pus existed in some part of the pelvis, for the pyemic symptoms were very marked. I did not do then, as I should now do under similar circumstances-operate at once,—but tried for nine months to make an abdominal section unnecessary. The uterus was curetted for the purpose of con- trolling the hemorrhage, but the operation did no good, and like results attended con- stitutional and the routine local treatment. Accordingly, on February 23 of the fol- lowing year I opened the abdomen. The exploring finger came in contact with a mass which was hard, rigid, and completely distorted the left broad ligament. The left ovary and tube could not be distinguished, but the fundus of the uterus was indistinctly outlined in the posterior cul-de-sac. A soft point was felt at the upper part of the mass on the left side, into which an aspirating needle was thrust, but the contents of the sac were too thick to be drawn off through the needle. I therefore opened the sac with a scalpel, and a teacupful of exceedingly offensive pus poured forth. I then enlarged the opening and found that the abscess included the ovary, which was nothing more than a shell. It was impossible to stitch the abscess walls to the parietal opening, so I broke down and removed its posterior wall, scraped away the secreting membrane, and applied to the entire raw surface, after thoroughly washing the abdominal cavity with sterilized water, tincture of iodin. PELVIC ABSCESS. 49I I then dug the right tube and ovary from inflammatory exudates, tied and removed them. A glass drainage tube was inserted and the abdomen closed. The tube was left in for five days. The patient made a somewhat tedious convalescence, but the improvement was finally of the most decided character. In four months' time she was doing her own work, including her washing, and had gained amazingly in flesh. and CASE LXVIII.—Pelvic Abscess following Hematocele; Laparotomy; Recovery. Mrs. II—, aged twenty-nine, was married at eighteen, had a child within the year, has never been pregnant since. . . The history given to me was that about nine weeks previously, when driving in an open carriage with her husband, on a very cold day, and during a menstrual period, she was suddenly attacked with a violent pelvic pain, and coincidently with it the discharge ceased. The pain had continued ever since, and had of late increased in severity. Menstruation had occurred at two irregular intervals since the beginning of her illness with great profuseness, and during these periods her pain had been much easier. A pelvic tumor had been discovered by Dr. Millington some weeks before my visit, and this he had regarded as an effusion of blood. She had suffered for about three weeks before I saw her from night-sweats, almost constant sickness, utter loss of appetite, intense thirst, with various other symptoms of pro- nounced hectic. The tumor, when I examined it, involved all of the pelvic organs in a fixed mass of cartilaginous hardness, with the uterus imbedded in it; the bladder spread over it in front, and the rectum was encircled by a ring of hard effusion. The mass could be felt about the pelvis as a round and non-fluctuating tumor, with intes- tine in front of it. The patient had reached almost the final stage of exhaustion and emaciation. There was no difficulty in diagnosing the case as one of suppurating hematocele. With Dr. Blackford's concurrence, we had her removed to Birmingham, and on the 21st I opened the abdomen and found matters quite as I had anticipated. The posterior layer of broad ligament was lifted completely up out of the pelvis, and so was the anterior layer, as far as I could make out; at least, the only structure I could identify was the base of the bladder, and that seemed to form the anterior boundary of the tumor. From this point it spread backward, on a level with the brim of the true pelvis, and its posterior boundary was the bifurcation of the aorta. The contents were clearly fluid, and therefore I tapped it with an aspirator needle, and evacuated about half a quart-bottleful of curdy, blood-colored pus. I then laid the cyst open from the point of puncture, in the direction from before backward, and found its floor to consist of a thick layer of laminated clot, hard and rigid. I could make out the uterus rising out of this mass, but I could not discover the rectum. I stitched the edge of the opening into the abscess to the edges of the parietal wound, and then enclosed the rest of the peritoneal opening, and fastened in a wide drainage tube of glass. After the operation the patient's temperature never rose above 37° C., she had no more night-sweats nor sickness, and her appetite was really keen on the third day. A small-sized wire drainage tube replaced the glass one on the twelfth day, as the discharge had become healthily purulent and free from clot débris. The smaller drainage tube was removed on the fifteenth day after the operation, and on the twenty-fourth the sinus was quite healed, she had gained greatly in flesh and color, was able to walk about, and on the twenty-seventh day she went home perfectly well, the uterus, however, being still quite fixed, as I expect it will remain for years. I have repeatedly seen this patient since the time of operation, and her health remains perfect to this day.-Lawson Tait. CHAPTER XXXII. DISEASES OF THE URETHRA AND BLADDER. ACUTE URETHRITIS AND CYSTITIS. ACUTE UREthritis. General Considerations.—In treating of vaginitis I dwelt upon the uncertainty of differentiating between the specific and non-specific forms of inflammation attacking the genital and urinary tracts. It was there stated that specific vaginitis oftener involves the urethra than does non-specific, and this is un- doubtedly true. Nevertheless, acute urethritis may occur inde- pendently of gonorrheal infection. In both forms of inflammation the patient will complain of a burning pain in the urethra, more or less severe, which is greatly aggravated by urination. It is, however, claimed by Skene that the history of the two affections is quite different. Simple urethritis," he says, "comes on gradually and is often preceded by symptoms of uterine or vesical disease, while the gonorrheal variety comes on rather abruptly and is preceded or attended by acute vaginitis or vul- vitis." A microscopic examination usually reveals gonococci in the discharge of specific urethritis.* (6 In both forms of inflammation painful spasmodic contractions of the canal, interfering with or preventing the flow of urine, are of frequent occurrence. The mucous membrane, upon physical examination, will be found red, congested, and exceedingly sensitive. By using an endoscope or speculum, mucus or pus will be found between its folds. ACUTE CYSTITIS. Frequency.—Acute cystitis in women is a disease probably more frequent than the student is led to infer from the teachings of many of our more prominent gynecological authorities. *v. pp. 74 and 381. 492 ACUTE CYSTITIS. 493 While it is a lesion not confined to women, yet the anatomical peculiarities of the female bladder are such as to make it more liable to inflammatory attacks than is the male bladder. The uterus and annexa, posteriorly and superiorly, frequently implicate it in a reflex way or by direct transmission; while the vagina is lined with a mucous membrane often the seat of specific or non-specific inflammation, which is readily conveyed through the urethra to the bladder. Again, the numerous injuries follow- ing in the train of parturition not infrequently end in inflam- mation of the organ. Pathology. In its pathology there is nothing peculiar or remarkable. The changes will vary somewhat according to the severity and violence of the attack, yet they are not unlike those found in inflammation attacking any mucous surface. At the outset the existing hyperemia gives a bright red appear- ance to the membrane, which soon becomes swollen and relaxed. At certain points the epithelium will be destroyed, particularly at the summit of the ruga, between the folds of which, and in the sulci, pus is usually found. These, in brief, are the ordinary changes incident to the disease. Occasionally the destructive process is much more decided, especially in certain cases follow- ing prolonged distention. All of the mucous mucous and sub- mucous tissues may become involved, the entire lining membrane of the bladder being shed or cast off en masse; usually this occurs only in post-puerperal cases, at which time the general conges- tion and succulency of all the pelvic organs favors extensive destruction. During confinement, pressure upon the neck of the bladder or upon the urethra causes tumefaction of the parts and consequent obstruction. As a result, the urine may be retained for an indefinite length of time, the dribbling from the over-distended organ deceiving both nurse and physician, until the excessive intra-vesical pressure cuts off the capillary circu- lation from the mucous membrane, causing, in due time, its partial or complete death, after which it is exfoliated and cast off. This, at least, is the explanation given by Liston, and it seems a very probable one. Skene suggests that where the dis- tention has been sufficiently great to cause separation, the death of tissue may be due to excessive congestion following sudden 494 A TEXT-BOOK OF GYNECOLOGY. emptying of the organ. The succeeding changes are those of chronic cystitis. Etiology. The etiological factors of acute cystitis are both numerous and varied, some having already been suggested. There is not a consensus of opinion as to whether or not it ever occurs as an idiopathic affection. While not as profoundly im- pressed by the causes giving rise to general pelvic congestion as are the uterus and ovaries, yet the blood supply of all of the pelvic viscera is derived from the same general source, and it therefore requires no great stretch of the imagination to believe that cold or undue exposure may excite cystitis. However, in the vast majority of instances, the trouble can be traced to un- mistakable exciting causes, though it is reasonable to believe that women of scrofulous tendencies are more liable to have catarrh of the bladder, when exciting causes exist, than are those free from constitutional bias. At any rate, the slightest irrita- tion or exposure will, in some women, set up congestion or actual inflammation of the bladder. Of the various exciting causes none is more important than parturition, to the improper conduct of which many a woman. owes her invalid life. Cystitis is here produced either by undue and prolonged pressure of the fetal head, by retention of urine, or by septic invasion-all preventable causes in most instances. Of those originating from within the body, abnormalities of the urine are to be noted, yet, in a bladder perfectly healthy, it is difficult to comprehend any unnatural condition of the urine sufficient to excite an inflammation. Unfortunately, many bladders are not perfectly healthy, being at all times more or less congested or abraded, a condition that may be transformed into true inflam- mation by urine loaded with lithates or with pus. Abnormal urine is oftener the result than the cause of cystitis. Of those originating from without the body we may enumerate traumatism, the introduction of foreign bodies by masturbators, uncleanly or unskillful catheterization, and unnatural or violent coitus. The bladder, like all other organs of the body, is predisposed to inflammation by any condition causing a chronic congestion. Disorders of the heart, liver, and kidneys act in this way. In acute exanthematous diseases the vesical mucous membrane ACUTE CYSTITIS. 495 may sympathize with the tegumentary tissues, and even become seriously involved. Certain drugs—cantharis, terebinthina, can- nabis sativa, etc.-possess the power, in doses sufficiently large, to inflame the bladder. As has been intimated under the head of pathology, diseases of contiguous organs may extend to the bladder. Urethritis, especially specific, frequently implicates the organ by extension of inflammation. Symptoms. Acute cystitis, while often giving rise to symp- toms most decided and pronounced, does not affect the organism as does chronic cystitis. In the simple types of catarrh the symptoms appear suddenly, there being a sensation of distress and weight back of the pubes, with increased frequency of mic- turition, which is more or less painful. The degree of tenesmus varies according to the extent to which the vesical neck is impli- cated. The urine is but little changed, is slightly acid or neutral in reaction, and may be clouded. The specific gravity remains normal, and if there is a sediment it will contain an increased quantity of leucocytes, with or without phosphatic crystals. Even when acute cystitis is purulent from the onset, the general disturbance may not be very great, except, as Richard- son observes, in those attacks due to bacterial invasion following labor. In these cases the onset is announced by a severe rigor, followed by a temperature ranging from normal in the morning to 103° or 104° in the evening. The hypogastrium may become very tender and the dysuria and tenesmus unendurable. In the purulent form the changes of the urine are more decided, it being ammoniacal, invariably alkaline, and containing pus and blood in varying proportions. The sediment contains, besides the blood- and pus-corpuscles, triple phosphate crystals, bladder epithelium, and bacteria. Those forms of acute cystitis which occur as a local expres- sion of severe constitutional disease-diphtheria, erysipelas, and croup-are always of serious import, and demand of the atten- dant prompt and vigilant treatment. Differentiation.-There may be some difficulty in differentiat- ing acute cystitis from acute urethritis, especially if the subjective symptoms alone are relied upon. Severe pain in the latter affection does not precede, and lasts but a short time after, 496 A TEXT-BOOK OF GYNECOLOGY. micturition. It is also said that there is an oozing of pus more. or less continuously from the urethra in urethritis; whereas in cystitis pus escapes only during micturition, and the urine which escapes last is more cloudy than that first discharged. The un- certainty of this test is, to my mind at least, very great. When the pus comes from the kidneys there will be more al- bumin than can be accounted for by the total quantity of the pus and blood present in the urine. Again, in renal disease the tube- casts, the absence of pain during micturition and in the region of the bladder, ought to direct attention to the kidneys. In prolapsus uteri there may be frequent urination not unlike that produced by cystitis, but the normal condition of the urine, and the aggravation arising from standing or walking, will at least suggest the cause of the trouble. The dysuria arising from vesical neuroses is characterized by its sudden appearance as well as by its sudden disappearance. If there is any change in the character of the urinary secretion it is but temporary. In adhesions of the bladder the desire to empty the organ is not urgent except when it becomes partially dis- tended. The urine remains unchanged. Fissure of the bladder can be positively determined only by the use of the endoscope. Treatment.—In the treatment of acute cystitis and urethritis prophylaxis is of the first importance, and the various causes enumerated should be carefully avoided or removed. Unclean catheters should be banished from the lying-in and operating room. I now use almost exclusively Kusner's glass catheter, the proper care of which is given in the chapter devoted to antisepsis. Unless absolutely necessary, catheterism after operations should not be resorted to. Even after abdominal section the patient is usually able to urinate with much less distress than is caused by the introduction of the instrument, and experience has fully de- monstrated the harmlessness of permitting healthy urine to come in contact with plastic operations if antiseptic injections are used. With the possible exception of vesical fistula, I no longer draw the urine after operations, except in those cases where swelling and tumefaction have temporarily occluded the urethra, or where, owing to some peculiarity of the patient, she cannot urinate while in the recumbent posture. ACUTE CYSTITIS. 497 On the other hand, catheterism is frequently called for in post-puerperal conditions, and the importance and necessity of examining the bladder carefully during the first few days of the puerperium should be indelibly impressed upon the mind of the student. A very large proportion of the cases of cystitis date from childbirth, and in no instance should the statement of either nurse or patient be relied upon as regards the passage of urine, especially if there be dribbling. In consultation with Dr. J. W. Wheelock of Bancroft, Mich., I once saw a parturient woman, moribund with symptoms of septicemia and uremia, whose bladder reached the umbilicus, giving to the abdomen, so great was the distention, the appearance of tympanitic enlargement. Catheterization rewarded us with two large-sized pots de chambre full of urine, the distention having been overlooked by two well-known physicians who had preceded Dr. Wheelock in the case. Abnormalities of the urine, when they exist, should be cor- rected, and hemorrhoids, fissures, or any disease of neighboring organs should be removed. Necessitas tollenda causa applies to the treatment of cystitis quite as much as it does to the treatment of any other inflammation. During the attack, rest, more or less absolute, should be in- sisted upon. The recumbent posture should be maintained, and if the vesical pain and tenesmus are very great, much relief may be afforded by the hot sitz bath or vaginal douche. If the urethra is the part chiefly implicated, a stream of warm water falling upon the external meatus for ten or fifteen minutes and repeated three or four times a day is often most useful. Con- centrated and irritating urine can be diluted by permitting the patient to drink freely of either water, milk, or some mucilagin- ous fluid. The diet should be unstimulating and bland, milk being the best of all articles. These precautions, in conjunction with the indicated remedy, will, in probably the larger proportion of cases of acute aseptic inflammation accomplish a cure. Aco- nite, belladonna, cantharis, cannabis sativa, chimaphila, mer- curius cor., and arsenicum comprise a list of remedies frequently useful. After the duration of a week or longer without manifest im- 32 498 A TEXT-BOOK OF GYNECOLOGY. provement, the disease will have assumed a subacute or chronic character, and may demand more direct local medication, the method of applying which, together with the therapeutic indi- cations, is given in the succeeding section. CHRONIC URETHRITIS AND CYSTITIS. Chronic urethritis is occasionally met with as a result of some distortion of the urethra-dilatation, prolapse, or backward dis- placement—the latter condition arising from contraction of the utero-sacral ligaments. It is oftener, however, the sequel of acute inflammation and may be exceedingly obstinate and per- sistent in its course. The symptoms have to do largely with the function of mic- turition, there being more or less pain and tenesmus, with a slight discharge of pus. The pus will be washed away by the urine first passed, that left behind, if drawn off subsequently, being comparatively free from sediment. The disease rarely exists for any length of time without sooner or later implicating the bladder. Chronic Cystitis.-The mucous membrane undergoes the usual changes of chronic inflammation, assuming a muddy gray color. The epithelium is freely shed and may be necrosed and ulcerated; or the membrane may be cast off en masse, as in the acute variety. The ulceration may extend into, and even perforate, the walls of the bladder. Hyperplasia sometimes takes place at the seat of ulceration, resulting in the development of polypoid material (Skene). As time goes on the sub-mucous intermuscular tissue becomes thickened-partly because of the extension of inflammation and partly because of the vesical tenesmus. When the disease extends to the muscular parietes it is known as interstitial cystitis; if the peritoneal coat is impli- cated, as epi-or peri-cystitis. Etiology. The same causes giving rise to the acute form of inflammation may, when acting less violently, set up the chronic form. Indeed, it is a frequent sequel of acute cystitis. Other causes are: foreign bodies, calculi, tuberculosis, cancer, paralysis, displacements of the uterus, perivesical inflammation, and irri- tating internal medicines. CHRONIC URETHRITIS AND CYSTITIS. 499 Symptoms. These are local and constitutional. The local symptoms are caused by the contact of urine with the inflamed walls. There is a desire to urinate as soon as a slight accumula- tion of the secretion occurs, micturition being attended with pain, tenesmus, and, frequently, spasm. The character of the urine is variable, depending upon the extent and chronicity of the disease. Its specific gravity is usually low, and it contains pus, epithelium, mucus, and, not infrequently, blood-cells. These various abnor- mal elements give rise upon standing to an albuminous, ropy deposit, more or less abundant. It speedily becomes alkaline and phosphatic and possesses a fetid, ammoniacal odor. The system is always more or less impressed by the persist- ence of the disease, sometimes most profoundly so. As time goes on, hypertrophy of the neck of the bladder ensues, which makes complete evacuation impossible. The urine thus retained becomes stale and increases the irritation. A certain quantity of pus and urinary elements are absorbed, so that the patient soon shows signs of cachexia and chronic septicemia. In the worst cases of ulceration there is infiltration of urine into and through the bladder walls, which occasionally terminates in abscess and serious pelvic inflammation; or the disease may implicate the opening of the ureters, giving rise to partial occlu- sion, the obstruction terminating in distention of these canals together with the pelves of the kidneys. The kidneys may be- come disorganized and suppurate, death occurring from pyemia and uremic poisoning. Even in the milder forms of chronic cystitis the patient shows the effect of the disease in various ways. She is constantly broken of her rest, being compelled to get up during the night from five to twenty times for the purpose of emptying the blad- der. This in itself soon tells upon her. Nutrition is always more or less affected, the appetite is impaired, and the counte- nance is indicative of suffering. Nervous symptoms of various kinds sooner or later supervene. Treatment. The general measures recommended in acute urethritis and cystitis are to be observed in the treatment of the chronic forms of inflammation. Diluent drinks-gum-arabic water, flaxseed tea, and slippery-elm water-are useful for chang- 500 A TEXT-BOOK OF GYNECOLOGY. ing the character of the urine. Drinking freely of some of the mineral waters for the purpose of diluting the urine is also bene- ficial. The waters most used for this purpose are the Vichy, Bethesda, Waukeshaw, and Buffalo Lithia. The diet should be nutritious but bland, it being best to eschew alcoholic beverages, spices, asparagus, etc. As soon as the evidences of pus become marked, in either urethritis or cystitis, the parts should be irrigated at least once or twice a day. Skene has devised a reflux catheter for irrigat- ing the urethra, which is shown in Fig. 80. With this instru- ment the urethra can be douched with water as hot as the patient can bear it and as often as necessary. It should only be passed as far as the neck of the bladder. The water used may be medicated with hydrastis, calendula, boracic, or carbolic acid. Skene has also devised a most simple instrument for washing FIG. 80. G. TIEMANN & CO Reflux CatheTER. (Skene.) out the bladder. It consists of a small glass funnel to which is attached a piece of rubber tubing eighteen inches or two feet in length. The distal end of the tubing is connected with a soft rubber catheter. I have substituted the glass for the rubber instrument. The catheter is introduced into the bladder, and the urine is drawn off through it-enough, however, being left behind to fill the tubing and prevent the entrance of air. The solution to be used is now poured into the funnel, which is raised sufficiently high to force the water into the bladder. After the bladder contains as much of the fluid as the patient can tolerate without pain, the funnel is again lowered and the fluid drained off. This can be repeated until the water returns clear. Care should always be taken to prevent air from entering the bladder. If the urethral tenderness is very great, before introducing CHRONIC URETHRITIS AND CYSTITIS. 501 the catheter, I apply to the urethra, by means of an ordinary dropper, a few drops of an eight per cent. solution of cocain. The choice of fluids to be used in washing the bladder should be governed by circumstances. There is nothing better than a two per cent. carbolic solution to prepare the way for a medica- ment. Skene prefers a solution of borax or common table salt (one tablespoonful to a quart), and Mundé recommends a tepid I: 1000 boracic acid solution. After the bladder is thoroughly washed in this way I add to the last pint of water injected the medicament, if one is indicated, and instruct the patient to retain three or four ounces of it for some minutes, so that it may come in contact with the entire mucous membrane. The remedies oftenest used by me for local medication are calendula and hy- drastis: calendula if there is a great deal of pus, or evidences of ' ulceration; hydrastis, if the deposit is composed largely of tena- cious mucus. The strength of each should be about 1:20. If good is to be obtained from this treatment, it must be em- ployed at least once or twice a day and persisted in for some time. If the bladder is washed but once or twice a week the improve- ment will be very slow, hence the nurse or attendant (and any intelligent nurse can do it) should make the treatment, under the direction of the physician. The carefully selected internal remedy is, of course, to be given in conjunction with the local measures recommended. Chronic cystitis, under the most favorable conditions, usually runs an obstinate course, and, in spite of the foregoing treatment faithfully and persistently carried out failures will every now and then result. The great difficulty to contend with is the constant contact of irritating urine with the inflamed bladder walls, thus making physiological rest impossible. There is but one way to overcome this difficulty, and that is to make an opening through the vesico-vaginal septum sufficiently large to permit the urine to drain into the vagina as soon as it enters the bladder. This operation is known as colpocystotomy. It is not difficult to perform and there is nothing more simple than closing the artificial fistula after the cystitis is cured. I have opened the bladder many times for chronic inflammation, and, except in one instance, have never failed to close the opening on the 502 A TEXT-BOOK OF GYNECOLOGY. first attempt. In the instance referred to the light was wretch- edly bad, and undoubtedly I coaptated an unvivified surface. This patient was brought to me by Dr. J. W. Ritter of Dexter, Mich. A second operation has not yet been made. In a given case of chronic cystitis I proceed, then, as follows: An attempt is first made to cure the disease by the measures which have been recommended. If these fail after a thorough trial, or if the local treatment is impracticable because of the very great pain which it induces, the patient is given an anesthetic, and an exploration made. Should there be found sufficient urethral disease-fissure, ulcer, angioma, etc.-to keep up the cystitis by the dysuria and tenesmus excited, and the bladder changes are not great, the disease is removed and the urethra dilated with some expanding instrument (Pratt's urethral speculum is excel- lent for the purpose) with the hope of relieving the tenesmus and curing the cystitis. I have succeeded in curing several cases in this way. If this procedure fail, or if the hypertrophy of the bladder walls be already marked, I then proceed to per- form colpocystotomy. Colpocystotomy. The patient is placed in the Sims posture and a good-sized male sound is introduced into the bladder, the point being made to impinge upon the trigonum vesica-midway between the neck of the bladder and the cervix uteri, in the median line. The point of the sound is cut down upon by means of a scalpel, when it is removed and the edges of the wound separated by two tenacula hooked into either side through the vagina. One blade of a pair of angular scissors is now passed into the opening, which is enlarged to the extent of an inch. Finally, the mucous membrane of the bladder is stitched to that of the vagina by a running interlooped catgut suture. Unless this last precaution is taken it is impossible to keep the wound from healing; even with it, the opening will close unless it is dilated with the finger once or twice a day for the first ten days. The bladder can now be gotten at for proper treatment, and washed through both the urethra and the artificial opening. The relief afforded is most remarkable, and the patient usually begins to gain at once. I have had patients gain thirty pounds in four months' time following the operation. They begin to eat almost DISEASES OF THE URETHRA AND BLADDER. 503 immediately, are no longer compelled to get up several times dur- ing the night in order to empty the bladder, and the symptoms of septicemia disappear. There is, to be sure, more or less inconven- ience and distress caused by the constant dribbling of urine into the vagina and its contact with the external organs. This can be largely overcome by frequent washings, and the application of some of the protective ointments recommended for pruritus vulvæ. I never have succeeded in successfully fitting any of the cup pessaries devised for the purpose of conveying the urine from the fistula into a urinal attached to the limb. The fistula should not be closed until the inflammation and ulceration are entirely cured. The length of time required to accomplish this is from three to eighteen months. It is a most remarkable fact-one that affords some idea of the suffering incident to cystitis-that patients who have undergone the oper- ation, notwithstanding that they are constantly wet from the dribbling of urine, are usually loath to have the opening closed, so great is the relief experienced. The technique of the operation for closing it does not differ from that required for fistulæ produced by other causes. Therapeutics. Cantharis.—TENESMUS VESICE; constant desire to urinate, pass- ing only a few drops at a time, often mixed with blood; stinging and burning pains in the region of the bladder before and after micturition, or cutting pains from the kidneys to the bladder; abdomen distended and painful to contact, especially in the re- gion of the bladder. Apis mel.-Great irritation at neck of bladder with frequent and burning urination; frequent desire with passage of only a few drops; BURNING AND STINGING IN THE URETHRA; useful in cystitis and urethritis caused by cantharis; bladder symptoms are aggravated by drinking water. "It seems as if the sight of water brings about a constriction of the sphincter muscle."— Farrington. Aconite.-High fever; restlessness; constant urging, yet fear- ful of evacuating urine on account of painfulness of the act; micturition difficult, sometimes only drop by drop. 504 A TEXT-BOOK OF GYNECOLOGY. Dulcamara.-Painful pressing down in the region of the bladder and urethra; especially useful in chronic cases with con- stant desire deep in the abdomen to urinate, particularly if brought on or perpetuated by exposure to local damp or cold; urine is very offensive and is loaded with mucus. Pulsatilla.—Tenesmus and stinging in the neck of the blad- der, the pain continuing after micturition; gonorrheal urethritis with thick yellow, or yellowish-green discharge; INFLAMED eyes; scanty urine with restlessness; suppressed gonorrhea.* Equisetum hy.-Urine high colored and scanty; dysuria with severe pain, especially just after voiding urine; pain and tenderness in region of bladder with feeling of distention. † Mercurius cor.-Fever with chilliness; violent urging; urine flows in a thin stream, or only drop by drop, containing mucus and pus; during micturition sweat breaks forth; SYPHILITIC URE- THRITIS; in children who perspire profusely, whose urine is hot and acrid, with sudden irresistible desire to urinate. Uva ursi.-Frequent urging with slight discharge and burn- ing, cutting pain afterward; the urine is yellow and deposits a tough mucus. Copaiva. Urethritis with burning at the neck of the bladder and in the urethra; the discharge is of a milky color and of a corrosive character. Cubeba.—Cutting and constriction after micturition; the dis- charge is of a mucous character.‡ *"In cystitis and catarrh of the bladder we find Pulsatilla indicated when there is frequent urging to urinate with pressure on the bladder as if it were too full. There is pain in the urethra. The urine itself is often turbid from the admix- ture of mucus. Clinically we have not found pulsatilla a first-class remedy in cysti- tis, but we have found it almost always the remedy in cystic symptoms accompanying pregnancy. It yields to cantharis, equisetum, and dulcamara in cystitis.”—Farring- ton. +"Equisetum acts very similarly to cantharis on the kidneys and bladder. There is, however, less escape of blood and less tenesmus vesicæ than may be found under cantharis. The urine is less scalding and does not contain so many fibrinous flakes. Cantharis is not called for so often as equisetum when there is an excess of mucus in the urine.”—Farrington. "Both Copaiva and Cubeba are useful in the irritation attending thickening of the lining membrane of the bladder. Neither remedy has as violent an action as has cantharis.”—Farrington. DISEASES OF THE URETHRA AND BLadder. 505 Petroselinum.-Sudden urging to urinate; gonorrhea with sudden urging and strangury. "In the case of a child it will be suddenly seized with a desire to urinate. If it cannot be grati- fied immediately it will jump up and down with pain.”—Far- rington. Ferrum phos.-Cystitis with dysuria, which is brought on by standing. Berberis vulg.-Cystitis associated with cutting lesions; sharp, stitching pains, radiating from the region of the bladder in all directions, particularly downward and forward, filling the whole pelvis with pain. Cannabis sat.-Sudden urging with difficult urination; cut- ting pains during micturition between the labia, with violent sexual desire; swelling of the vagina; the orifice of the urethra is closed with muco-pus. Belladonna.-The region of the bladder is sensitive to touch; urine hot and red; shooting pains; cerebral excitement. Arsenicum.—Burning pain, especially at commencement of urination; chronic cystitis with inability to void the water; symptoms of sepsis; urine turbid and mixed with mucus and pus. Lycopodium.-Chronic cystitis with fever; disposition to urin- ary concretions; URIC ACID DIATHESIS. Terebinthina.—Sensitiveness of hypogastrium; tenesmus of bladder with strangury and pain in urethra; urine retained from atrophy of fundus vesicæ; catarrh of the bladder in old persons of sedentary habits. Camphora. Especially useful after abuse of cantharis and terebinthina; complete suppression of urine; slow and thin stream; burning in urethra and bladder; Consult:-Elaterium, eupatorium purp., helleborus, populus, sepia, hyoscyamus, lachesis, sulphur, and tarantula. CHAPTER XXXIII. DISEASES OF THE URETHRA AND BLADDER (Continued). MALFORMATIONS OF THE Urethra. Congenital malformation of the urethra is usually associated with more or less malformation of the sexual organs and requires no extended description. The canal may, however, be entirely absent when the genital organs are normal, or it may be imper- fectly developed at its lower portion only (hypospadiasis). A more common congenital defect is complete atresia. A case is recorded by Skene in which delivery was impeded by the dis- tended fetal bladder, caused by atresia. The treatment of these various abnormalities is purely surgical. STRICTURE OF THE URethra. As in the male, though much less frequently, gonorrhea and non-specific inflammation may result in stricture of the urethra, and even in complete atresia. Stricture more or less marked is also met with in long-standing vesico-vaginal fistula sufficiently large to permit all of the urine to pass through it. The contraction may involve the entire length of the canal or only a portion of it, being oftener confined to the meatus. In difficult or painful mic- turition the possibility of stricture should always be borne in mind and the caliber of the canal measured. This is done by means of a sound, carefully inserted. The normal female ure- thra should admit with perfect ease a number twelve male sound (English scale). Distortion of the canal without stricture some- times interferes with its introduction. · The same principles observed in the treatment of stricture in the male urethra are applicable to stricture in the female. Gra- dual dilatation is preferable to rapid if it will accomplish the desired end, as it usually will. This can be done by the repeated introduction of graduated sounds, cocain being first used if the 506 PROLAPSE OF URETHRAL TISSUES. 507 pain is great. If this fail, rapid dilatation under ether may be made, using for the purpose an ordinary smooth steel uterine dilator or Pratt's urethral speculum. The graduated sounds should be passed at frequent intervals after this operation. PROLAPSE OF THE MUCOUS AND SUBMUCOUS TISSUES OF THE URETHRA. The most frequent cause of this accident is parturition. The mucous membrane and submucous tissues become, according to Emmet, split or lacerated in the long axis of the canal as the urethra is squeezed between the arch of the pubes and the fetal head. The peculiar loose structure of the tissues causes them to be rolled out from the urethra in advance of the child's head, the mechanism being not unlike that which forces the rectal mucous membrane from the anus. The slight degree of prolapse in many of these cases is indi- cated only by the deeper red color of the urethral surface pre- senting itself at the outlet, for the retraction resulting from cica- trization prevents a more serious displacement. Troublesome symptoms do not always immediately follow the injury, and the patient may not be conscious of the accident for some weeks or months afterward, when the unnatural sensations are often attri- buted to some displacement or lesion of the uterus. Usually, however, the trouble can be traced back to some particular labor, after which pain and uneasiness at the neck of the bladder were experienced for the first time. A subsequent examination will reveal prolapse at the outlet of the urethra, occupying, as the case may be, either the entire circumference of the canal, or only the lower or upper portion of its orifice. Fig. 81 represents an exaggerated instance of urethral pro- lapse, which came under my observation during the fall of 1886. The case is the one referred to on page 207. The con- dition shown had existed for eighteen years, giving rise to a most distressing reflex asthma, which was entirely cured by re- moving the prolapsed tissue. The tumor was as large as a hen's egg. A careful physical examination, followed by the introduc- tion of the sound or catheter, is usually sufficient to distinguish the accident from caruncula, polypus, and venous angioma. 508 A TEXT-BOOK OF GYNECOLOGY. Treatment. If the prolapse is at all marked, surgical interfer- ence is usually necessary. It may be aggravated by existing pelvic cellulitis or anal fissures, in which event treatment should also be directed to these affections. The tissue was removed in the fore- going case by making a superficial incision around the base of the tumor, transfixing it with a double ligature, tying on either side, as in dealing with hemorrhoids, and cutting the mass away. Seguin first introduces a female catheter into the bladder, and then strangulates the tumor with a ligature thrown around its base. The catheter is not withdrawn until the base of FIG. 81. A B A. TUMOR. B. CATHETER INTRODUCED INTO URETHRAL ORIFICE, C. (Wood.) the tumor is entirely severed. It may also be removed by the galvano-cautery wire, as suggested by Thomas. Emmet condemns the removal of the mass in the circular variety of urethral prolapse. He says that many times only tem- porary relief follows the operation, while a serious and perman- ent stricture often results. He first reduces the hypertrophied tissues by making an artificial vesico-vaginal fistula, thus divert- ing the flow of urine from its natural outlet. Then, by the aid of a steel or block-tin sound, he carefully returns from time to time DILATATION OF THE URETHRA. 509 the prolapsed tissues, which are made to contract by the applica- tion of strong tincture of iodin introduced through a conical ear speculum, or some similar instrument. After the urethra is res- tored as near to its normal condition as is possible by this treat- ment, he performs an operation for the cure of the prolapse in this way: A button-hole incision is made in the urethra through which the excess of tissue is drawn back from the meatus, secured in its edges, and cut off, after which the opening is closed. This oper- ation is an ingenious one and, when the prolapsed tissues are not too much hypertrophied, is undoubtedly more satisfactory than is the one done by myself. The hypertrophy, however, in the case given, was such as to make Emmet's operation imprac- ticable. DILATATION OF THE URETHRA. This may result from growths within the canal, from stricture at or near the meatus, from the introduction of foreign bodies, or from the passage of calculi. In atresia of the vagina, the urethra may be sufficiently dilated to receive the male organ during intercourse. Thorburn cites a case of atresia vaginæ in which the urethral dilatation was so great that injections were given through it into the bladder, the urethra simulating the vagina. Oftentimes there is chronic inflammatory thick- ening of the mucous membrane. Symptoms.-Disturbed micturition will attract attention to the urinary organs. Upon physical examination there will be found either a tumor of some kind which has given rise to ob- struction of the urethra at its lower orifice, or inflammatory hypertrophy of its mucous membrane. A sound introduced beyond the point of obstruction will reveal the increased caliber of the canal. Urethritis is often associated with the condition, the discharge being purulent or muco-purulent in character. Treatment. If the dilatation is not great it may be treated by astringents, hot douches, etc. Any obstruction at or near the meatus should be removed. In the event of cystocele or relaxation of the pelvic floor these conditions should be cor- rected. If the dilatation is not overcome by these several methods, Emmet's button-hole operation will afford relief from Uor M 510 A TEXT-BOOK OF GYNECOLOGY. the distressing symptoms. The opening is made at the most dependent part of the urethra, either with a sound or scalpel, or with button-hole scissors especially constructed for the purpose. The mucous membrane of the urethra is then stitched to that of the vagina by a running catgut suture, as in colpocystotomy. If the urethral mucous membrane is very redundant, a portion of it may be excised. This opening affords free drainage and greatly facilitates irrigation, as well as the application of medica- ments. Or, Skene's operation for prolapse of the urethra may be resorted to. This consists of an incision half-an-inch long on either side of the urethra, extending from the vulva upward and outward. With a continuous catgut suture the tissues are attached to the fascia of the sub-pubic ligament. The first row of sutures is buried while the edges of the wound are retracted; the second unites the divided mucous membrane. The tissues are thus gathered together on each side of the urethra and the prolapse is overcome. FISSURE OF THE Urethra. The mucous membrane of the urethra, like that of the rectum, is sometimes rent in such a way as to create a fissure. In the urethra it is usually located at its vesical extremity. It may give rise to very distressing dysuria, with tenesmus and spasmodic contractions of the bladder. The diagnosis will have to be made by exclusion-there being an absence, on physical exploration, of those lesions attended with similar symptoms. An expert with the endoscope may be able to see the fissure, but this is extremely difficult when the lesion is located high up in the canal. The treatment consists of both internal and local medication. Magnesium phos., cantharis, mercurius cor., and cannabis sativa will be the remedies oftener indicated. I have succeeded in curing several cases by protecting the fissure with oleaginous collodion, as recommended by Ludlam. The solution is brought in contact with the parts by means of an ordinary straight medi- cine dropper, the tip being inserted as far as the neck of the bladder. Suppositories composed of iodoform, bismuth, or belladonna sometimes do much good. Maou VASCULAR NEOPLASMS: URETHRAL CARUNCLES. 511 As a last resort dilatation may be made and it usually accom- plishes a cure. I have, in another place, cautioned against too great dilatation of the urethra because of the danger of inconti- nence. The rule laid down by Skene, and it is a good one, is this: Ascertain how large a sound can be passed with ease and then dilate sufficiently to admit another three or four sizes larger. If this rule is carefully observed there will be but little danger of creating incontinence. Finally, if forcible dilatation fail to produce sufficient physi- ological rest to cure the disease, an opening may be made into the bladder through the vagina. This will keep the urine from coming in contact with the fissure, and by the time the artificial opening closes spontaneously, the lesion probably will have healed. VASCULAR NEOPLASMS OF THE URETHRA. An increase in the caliber of the venous radicals will give rise to over-distention and the formation of tumors, which are known as angiomæ, varices, or phlebectases. They are analo- gous to rectal hemorrhoids and may occupy any portion of the urethra, though the vessels of the urethro-vaginal septum are the ones oftener implicated. These growths, unlike urethral caruncles, are not painful. The treatment is the same as that recommended for urethral caruncles. URETHRAL CARUNCLES. Skene describes these formations under the head of Compound Neoplasms. They are, technically, papillary polypoid angiomas, and vary in size from a millet-seed to a hazelnut. They are of a crimson or deep red color, soft, friable, more or less peduncu- lated, and exquisitely painful to touch and upon passing urine. They spring from the urethral wall near the meatus. Occasion- ally they are concealed entirely within the urethra, or they may completely encircle the meatus, resembling the minor degrees of prolapse of the urethral mucous membrane. Histologically, these growths are made up of fine loops of 512 A TEXT-BOOK OF GYNECOLOGY. capillaries, with a limited amount of connective tissue and a varying supply of nerves. Symptoms.-Pain upon micturition, sometimes very great, is usually the chief symptom for which the patient seeks relief. Dyspareunia and vaginismus may be most distressing. If large enough to interfere mechanically with urination, the act is not only painful, but difficult as well. These growths can be differentiated from angioma by their greater sensitiveness, their brighter color, and their tendency to bleed. They do not shrink under pressure, as do the vascular neoplasms. Treatment.-This consists in total ablation of the morbid growths, either by means of scissors, the actual cautery, or caustics. My method of operating is as follows: The patient is placed in the lithotomy posture and the parts exposed; a twenty per cent. solution of cocain is then applied to the growth or growths by means of absorbent cotton. The tumor is next seized with a pair of tissue forceps and put upon the stretch. It is then removed close to the healthy structures by means of the Pacquelin, or the galvano-cautery knife. By this method the extent of tissue destroyed is entirely under the control of the operator, which is not the case if caustics are used. Should the tumor or tumors be located higher up in the urethra, à speculum will be necessary in order to expose them. Skene recommends Allen's ear polypus forceps for grasping the tumor under these circumstances. When still higher up in the canal it may be necessary to use the snare, for which purpose Blake's polypus snare will be found useful. POLYPI OF THE URETHRA. Occasionally polypi spring from the urethra. Urethral caruncles may take on a polypoidal form; these have already been considered. Small pedunculated fibromata may also be located in or about this canal. And, most rare of all forms, are occluded glandules, which assume a polypoidal shape. The treatment is, in all instances, surgical and does not differ from that given for urethral caruncles. IRRITABLE URETHRA: VESICAL CALCULI. 513 IRRITABLE URETHRA. The mucous membrane of the urethra, like the mucous mem- brane of other parts of the body, sometimes becomes irritable or hyperesthetic without any local disease to account for such irritability. The condition is not unlike that of the so-called hysterical rectum so graphically described by Weir Mitchell. It gives rise to frequent micturition, especially after undue exercise or nervous excitement; and pain during sexual intercourse. The most careful examination will fail to reveal local evidences of disease. The treatment is dilatation according to the same method recommended for fissure of the urethra. The operation may have to be repeated several times, but in the end will, in nearly all instances, accomplish a cure. Of course proper measures, having for their object the correction of any constitutional bias that may exist, should be observed. Galvanism is also beneficial. VESICAL CALCULI. Stone in the bladder does not occur in women nearly so often as in men. When it does occur the causes are much the same as in the male, the uric acid diathesis being responsible for it oftener than anything else. Foreign bodies are more apt to find their way into the bladder in women than in men, being usually introduced for purposes of masturbation. Thus, through the urethra, hair-pins, matches, and even spools, have been introduced for this purpose, around which incrustations may form. In all cases of chronic cystitis the bladder should be sounded for stone. When a metallic instrument comes in contact with it the sensation elicited is sufficiently characteristic to make the diagnosis certain. Sometimes the calculus is so large that it can be detected on bimanual examination. The treatment is essentially surgical, and measures should be taken to remove the foreign body as soon as it is detected. If the stone is small, an attempt may be made to crush it through the urethra by forceps or the lithotrite, after which the detri- tus can be washed away. However, a large stone should not be 33 514 A TEXT-BOOK OF GYNECOLOGY. removed in this way. The bladder is so easily gotten at through the vagina as to make it unwise to jeopardize the ure- thra by over-stretching. Indeed, in nearly all instances of vesical calculus there is a cystitis which is best cured by colpo- cystotomy. In a case operated upon by me for Dr. L. E. Gal- lup of Marshall, I removed, per vaginam, a stone weighing nearly 600 grains, the only anesthetic used being cocain. Notwithstanding the large opening required, no effort was made to close it and it healed spontaneously in less than three weeks' time, the drainage afforded curing the cystitis. NEOPLASMS Of the BladdER.* The various neoplasms occurring in other parts of the body may have their origin in the bladder. The villous variety of cancer is the one most frequently found in this locality. It usually runs a rapid course, yet sometimes the duration of the disease will extend over a period of several years. Cancer gives rise to a good deal of pain and the urine is often tinged with blood. A diagnosis can be made by the use of the cysto- scope, but ordinarily it is necessary to explore the bladder either through the urethra or through the vesico-vaginal septum. The prognosis is unfavorable, though life may be prolonged for an almost indefinite period by removing the growth as thoroughly as possible with a sharp curette, the hemorrhage being controlled by hot irrigation. Care must be observed not to injure the ure- ters in the efforts made to remove the disease. The other neoplasms found in the bladder are pathological curiosities. Cysts containing hair, teeth, sebaceous matter, etc., sometimes, though rarely, exist as indigenous tumors. In the vast majority of instances, these substances, when found within the bladder, are of outside origin. Polypi of varying structure-true fibromata, fibroid hypertrophy of the mucous membrane, tubercu- lar growths, etc., are likewise occasionally found within the bladder. It is exceeding difficult to differentiate these various growths from malignant disease, unless a portion can be removed. and subjected to microscopic examination. In all instances * The reader is referred to the excellent monograph on "Tumors of the Bladder," by Sir Henry Thompson, F. R. C. s., London, 1884. IRRITABILITY OF THE BLADDER. 515 an attempt should be made, either through the urethra or through an artificial vesico-vaginal fistula, to remove them. VESICAL PARASITES. In this climate these are almost unknown. They usually reach the bladder either through the urethra, through fistulæ, or by passing downward from the kidneys through the ureters. Vesical parasites are very much more frequent in tropical or sub-tropical regions. True hydatids are occasionally met with in the bladder, as in all other parts of the body. The symp- toms are those of vesical irritation, with occasional attacks of hematuria. If the parasites pass from the kidneys through the ureters the patient will suffer during their transit from all the symptoms of nephritic colic. An effort should be made to remove them through the urethra. HEMATURIA. So-called hematuria is a symptom of several of the condi- tions which have already been studied. It may be due to pur- pura or hemophilia, to simple local congestion, to fungosities of various kinds, to kidney lesions, to calculi, to foreign bodies, or to zymotic and malarial diseases. It is always important to determine the source of the blood when it appears in the urine. If there are clots large enough to be visible to the unaided eye, the source of the hemorrhage must be below the secreting structures. If the bladder is the source, the clots are often large and may lodge in the urethra, causing retention of the urine. If the coagulation takes place within the ureters, this will be indicated by the shape and size of the clots; if from the substance of the kidney, the clots, having been formed in the tubules, will be of microscopic size, and the urine will usually have a smoky tint. (Vaughan.) IRRITABILITY OF THE BLADDER. The same factors inducing irritability of the urethra may also give rise to irritability of the bladder. hysterical and very nervous patients. It occurs oftener in There are, however, other causes, which give rise to frequent micturition by inducing 516 A TEXT-BOOK OF GYNECOLOGY. irritability of the bladder. Of these anteversion and ante- flexion are the most frequent. Irritability of the bladder is also a common symptom of early pregnancy, and is due both to the increased weight of the uterus, the fundus resting upon the bladder, and to the exaggerated pelvic congestion. Indeed, any condition increasing the blood supply of the pelvis may cause irritability of the bladder. It is not infrequently associated with dysmenorrhea, tumors of the uterus and of the ovaries, pelvic inflammation, and periuterine hematocele. In all instances of irritability, however, the urethra should be carefully explored for excrescences and inflammation, and the urine examined for evidences of organic disease of the urinary organs. The cause of the irritability will sometimes be found in the urine itself, as when it is excessively acid or contaminated with pus or blood. Fine oxalates are often present in the urine of nervous and gouty subjects, and give rise to much irritation. They may be detected with a fairly good microscope. RETENTION of Urine. This may result from purely nervous causes, or it may be due to organic disease of the bladder. In In nervous cases the urine is sometimes retained for several days, and there may be almost absolute suppression, which condition is known as hysterical ischuria. The retention is often voluntary in cases of irritable carunculæ and other diseases of the urethra, the patient dreading the pain resulting from micturition. Retention frequently occurs, too, after operations upon the rectum, it being often necessary to use the catheter for several days following divulsion of this organ. As in the male, it is a frequent symptom in paraplegia, and the bladder should always be watched in cases of paralysis of the lower half of the body. Temporary paralysis of the bladder may also result from over-distention of this organ; after a certain degree of distention is reached, the urine cannot be ex- pelled. This condition frequently prevails in puerperal cases, and the distention may be so great as to produce a dribbling of urine without creating the slightest desire to evacuate the blad- der. RETENTION OF URINE. 517 It may likewise be due to any of the various lesions or dis- eases which give rise to pressure upon the neck of the bladder or upon the urethra, the retention being purely mechanical. Impacted fibroid or ovarian tumors, pelvic abscess, retro-uterine hematocle, incarcerated retroversion or retroflexion of a gravid uterus-any or all of these several conditions exert pressure and tend to obstruct the flow of urine. I have elsewhere cited a case (p. 62) in which the distention was so great as to give rise to suspicions of pregnancy. In all instances in which the patient has not urinated for some time, or in which there is a dribbling of urine, the bladder should be carefully examined for retention. It will be indicated by dulness in the hypogastric region, by bearing down intermittent pains, and by a sensation of distention in the lower abdomen. Care should always be taken to differentiate retention from suppression of the urine. In all cases of doubt the catheter will clear up the diagnosis. After the retention is temporarily relieved by the introduction of the catheter (in excessive distention the bladder must not be too suddenly emptied), measures should be taken to remove its cause, whatever it may be. In cases of temporary paralysis the catheter may have to be used for several days. Local faradization will here do much good. Belladonna, nux, gelsemium, camphora, and opium are to be thought of as inter- nal remedies. If due to paraplegia, the vesical paralysis is likely to remain as a permanent condition. CHAPTER XXXIV. FISTULÆ OF THE FEMALE GENITAL ORGANS. VESICAL AND URETHRAL FISTULÆ. The varieties of vesical and urethral fistulæ are: Vesico-vaginal; Urethro-vaginal; Uretero-vaginal; Vesico-uterine; Uretero-uterine. The location of the several fistulæ enumerated is clearly indi- cated by the names given. Of these vesico-vaginal fistula is by all odds the most frequent. The urethro-vaginal is rarely met with except when the opening is artificially made. The uretero- vaginal and uretero-uterine are still more rare accidents and, when they occur, usually result from some operative procedure within the pelvis. Pathology. The extent of tissue lost varies greatly. There may be but a small opening, barely admitting a fine probe, con- necting the vagina and bladder; or the whole base of the bladder may be destroyed, together with the urethra. All forms of fistulæ tend to become smaller from secondary contraction as time goes on. At first the margins are thick, irregular, and, frequently, ulcer- ated; later on, however, cicatricial contraction causes them to become thin and firm. As time progresses, contraction and thickening of the bladder walls take place; and, if the opening between the bladder and the vagina is very large, the vesical mucous membrane may protrude through it. In extensive fistulæ the destruction of tissue. may involve the openings of the ureters. The urethra, from want of use, also becomes contracted, and, indeed, atresia of this organ may occur. Often, too, there is associated with the acci- dent injury to the vagina with resulting cicatricial contraction. 518 URINARY FISTULÆ. 519 This may so distort the canal as to make it difficult to ascertain the size and location of the fistula. It is exceedingly difficult to locate vesico-uterine fistulæ, and in order to do so it is necessary to dilate the cervical canal. These fistulæ are usually small. Uretero-vaginal fistulæ are located in one of the fornices of the vagina.. They, too, are very small, admitting the point of a fine probe only. Uretero-uterine fistula so rarely occur as to constitute, when they do, pathological curiosities. Etiology. The causes of fistulæ may be enumerated as follows:- Injuries received during labor; Traumatism; Ulceration and abscess. Of these, the injuries and accidents incident to childbirth are of first importance. Long continued pressure of the fetal head is a most prolific cause. It may, however, follow rapid labor, the tissues being unduly bruised by compression between the fetal head and the bony pelvis. In either event death of tissue ensues from the unnatural pressure, and subsequent sloughing gives rise to fistula. use. Unquestionably, fistulæ may be produced by the unskilful ap- plication of instruments. However, in by far the larger number of cases the accident results, not from the intelligent application of the obstetric forceps, but rather from too long deferring its After the head has been wedged in the pelvis for a long time the mischief is already done; and, while there is danger of immediate laceration attending the use of the instruments, the primary cause of such laceration is, in neglected cases, the long-continued pressure which has made the tissues fragile. I especially emphasize this point because too often the attending physician, with whom the responsibility entirely rests, holds the consultant responsible for an accident which might have been avoided had the forceps been applied earlier. In the various other obstetric operations, especially those in- volving the destruction of the fetus, there is danger, if the instru- ments are carelessly used, of lacerating the vaginal walls. When 520 A TEXT-BOOK OF GYNECOLOGY. craniotomy is performed care should be taken that the sharp edges of the cranial bones do not produce such injury, or that the crotchet and blunt hook do not slip during traction and in- jure the vagina. Of the traumatic causes, the most frequent is a fall upon some sharp object. This occurs oftener in children and young girls than in adults. The careless manipulation of instru- - ments within the vagina in the various operative procedures through this canal may give rise to fistulæ. I unwittingly penetrated the bladder in one case of vaginal hysterectomy. Symptoms.-The first symptom suggesting the presence of the accident is incontinence of urine. This may be partial or absolute, depending upon the size of the fistula. If the opening is very small, part of the urine may be passed through the urethra. In almost all instances, however, in any of the forms of vesical fistula, the entire quantity of urine passes through the unnatural opening. This is frequently the only symptom, though in those cases where there is sloughing of tissue or ulceration, the local pain and distress are sometimes very great; or, if inflammation attends the accident, the usual symptoms of cystitis and urethritis manifest themselves. When the accident follows parturition, there is usually more or less paralysis of the bladder for several days preceding the formation of the fistula, during which time the frequent use of the catheter is necessary. After the separation of the slough the urine escapes through the vagina. This may remain as a permanent condition; or, if the opening is not large, subsequent cicatrization may result in its closure, when the urine will again be passed through the natural channel. The secondary symptoms of urinary fistulæ are due to con- tact of the urine with the vagina, external genital organs and neighboring surfaces. The labia, the perineum, and the inner surface of the thighs become red, inflamed and even ulcerated. It is exceedingly difficult for the patient to keep herself free from the urinous odor arising from this condition. Often, too, urinary deposits, consisting of urates and phosphates, form in crusts about the edges of the fistula and within the vagina, giving rise to great irritation. URINARY FISTULÆ. 521 The foregoing symptoms will clearly indicate that some un- natural condition of the urinary organs exists; but in order accu- rately to locate the fistula a physical examination is necessary. Physical Signs.-If an exploratory examination is made soon after delivery, great gentleness should be practised. In the event of a large opening between the vagina and the bladder, the finger will readily pass into the latter organ, and the diagnosis is easily made. Greater difficulty will be experienced if the opening is very small; in that case its exact location is sometimes hard to determine. In the event of doubt, proceed as follows: Place the patient in the Sims posture, before a good light. Introduce into the bladder through the urethra a catheter, to which is attached a rubber tube and funnel such as is used for washing out the bladder in cystitis. Through this distend the bladder with some colored fluid-milk or a weak solution of permanganate of potash. If the fluid escapes through the fistula, the location of the latter will be determined. In the event of vesico-uterine fistula the fluid will escape through the external OS. If the opening cannot be located by this method, the colored fluid failing to make its appearance after being forced into the bladder, either through the vagina or through the cervical canal, it is reasonably certain that there is no connection between the bladder and the vagina, or between the bladder and the uterus. This test is not absolute, for there may be a valve- like condition of the vesical mucous membrane, which will prevent the escape of the fluid from that viscus. Should such an opening not be found, the fornices of the vagina should be carefully explored for a ureteral fistula. Repeated examination may be necessary before a small fistula is finally located. It is sometimes possible, in vesico-uterine fistula, to pass the sound from the bladder into the cervical canal, at which point it is detected by passing a second sound through the external os. Prognosis. Simple fistulæ resulting from childbirth are many times spontaneously cured. After the opening once be- comes permanent, however, a spontaneous cure never results. The curability by operative procedures will depend upon the size 522 A TEXT-BOOK OF GYNECOLOGY. of the opening, its location, its cause, and the complications due to changes within the vagina. Fistulæ involving the base of the bladder are more easily gotten at and are, consequently, more amenable to treatment. On the other hand, vesico-cervical fis- tulæ and ureteral fistulæ, particularly the latter, present special difficulties. In dealing with the ureter, it is very difficult to prevent permanent stricture of the canal. Treatment.-Whenever a urinary fistula is suspected the catheter should be introduced at once in order to make sure that the discharge does not come from the urethra because of over- distention of the bladder. If it is evident that the urine escapes through the vagina, the patient should be placed in a favorable posture for examination, and the opening carefully looked for. If it is small, the urine should be drawn every three or four hours, or else a self-retaining catheter kept constantly within the blad- der. For this purpose I know of nothing better than the glass instrument of Kustner held in situ by strips of adhesive plaster. I much prefer it for this purpose to the Skene-Goodman cathe- ter recommended by most writers. (Fig. 82.) FIG. 82. G.TIEMANN-CO. SKENE'S MODIFICATION OF GOOD- MAN'S SELF-RETAINING CATHETER. It is necessary to keep the patient upon her back in order to prevent the lochial discharge from passing into the bladder. The vagina should be kept absolutely clean by the frequent use of a 1: 4000 bichlorid douche. In every respect the most scrupulous cleanliness should be practised. By observing these precautions a cure will result in a goodly per cent. of cases. This is especially true if the fistula attends any of the operations within or through the vagina. In the case referred to, in which it followed vaginal hysterectomy, the open- ing was large enough to permit the introduction of the finger, yet it healed perfectly in less than two weeks' time. It is not wise to undertake to close the fistula too soon after parturition-not earlier than three months. The best results. cannot be obtained until after the patient has passed through the puerperal changes. It is always wise, under any circumstances, to get the system into the best possible shape before undertaking URINARY FISTULÆ. 523 to close the opening, bearing in mind, of course, the fact that the existence of the fistula may be responsible for the continued ill-health. OPERATION FOR VESICO-VAGINAL FISTULA. A certain amount of preparatory treatment is usually neces- sary in order to obtain the best results. If there is local inflam- mation, this should be treated by frequent douchings and suitable medication. If the irritation about the external genital organs is great, Lyster's ointment of boracic acid, or some of the ap- plications recommended for pruritus vulvæ, will add greatly to the patient's comfort by relieving the excoriation. All incrusta- tions which form on the edges of the fistula and within the vagina should be removed with forceps at least every two or three days. If there are any evidences of cystitis, this should be dealt with by washing the bladder through the urethra. If the fistula is of long duration, it may be necessary gradually to dilate the urethra in order to insure its patulency when the flow is directed through it. This can be done according to the method described in dealing with stricture of the urethra (page 506). Should there be stricture of the vagina, or cicatricial bands which exert traction upon the bladder, these must be overcome before an effort is made to close the opening. The cicatricial bands should be divided and the canal kept dilated for a suitable length of time. Should it be impossible to remove entirely the scar-tissue, much good can be done by constant dis- tention with vaginal tampons, used for some weeks previously to the operation. The patient should be placed in the Sims posture before a good light. It is best to administer an anesthetic, not because of the excessive pain attending the operation, but because of the importance of perfect quiet on the part of the patient. Sims' speculum is a sine qua non. The operator cannot very well get along with less than four assistants-one to hold the speculum and elevate the nates, a second to care for the irrigator and do the sponging, a third to look after the instruments, and a fourth to administer the anesthetic. If but three assistants are available, the operator can himself manage the instruments 524 A TEXT-BOOK OF GYNECOLOGY. by having the tray near at hand. It is best to have a variety of needles of various curves and lengths with silk leaders secured in the eyes. The instrument tray should contain: Long-hand- led, curved scissors; at least two tenacula; wire twister; long- handled knife with narrow blade; needles and needle holder; counter-pressure hook; Sims' speculum and fork; and silver wire Nos. 29 and 30. In addition there should be from four to six sponge holders containing sponges of suitable size. The steps of the operation are three :- 1. Vivifying the edges of the fistula; 2. The introduction of sutures; 3. Coaptating the edges of the fistula and securing the sutures. FIG. 83. G.TIEMANN-CO. SIMS' CURVED SCISSORS. FIG. 84. 80 G.TIEMANN-CO BOZEMAN'S STRAIGHT SCALPEL. Vivifying the Edges of the Fistula.-The lower edge of the fistula should be first vivified. This is done by picking up the tissues, either with a tenaculum or tissue forceps, as the operator may prefer. I use almost entirely in plastic work tena- cula instead of tissue forceps. Then with a pair of curved scissors (Fig. 83) or with a long-handled narrow scalpel (Fig. 84) a strip of tissue is removed three-eighths of an inch in width, extending down to the mucous membrane of the bladder. Personally I pre- fer the scissors for this purpose. Care should be taken not to in- jure the vesical mucous membrane, because it is very vascular and, if injured, hemorrhage into the bladder is liable to occur. A strip of tissue of suitable width can ordinarily be removed in an unbroken piece. After the lower edge of the wound is vivified URINARY FISTULE. 525 the upper edge is dealt with in the same way. The denudation should extend sufficiently beyond the angles of the fistula to insure against puckering when the edges are coaptated. The parts should now be carefully inspected in order to ascertain whether or not any point has been left unvivified. If so, this is to be picked up with a tenaculum and snipped off. An unvivi- fied island of tissue might spoil the whole operation. FIG. 85. The direction of the long diameter of the fistula will determine the line of coap- tation. When it can be done this should corres- pond to the long diameter of the vagina. Should, however, the long diam- eter of the fistula run transversely, the line of FIG. 86. METHOD OF PARING WITH KNIFE. (Savage.) METHOD OF PARING WITH SCISSORS. (Savage.) coaptation will have to correspond to the transverse diameter of the vagina. The hemorrhage is usually not great and can ordinarily be controlled by hot irrigation. Should there be troublesome bleeding from an injured artery, it can be controlled by passing around it a fine catgut suture and tying this upon the vaginal surface. It is not a good plan, if it can be avoided, to leave even a fine catgut suture between the vivified edges of a fistula. 526 A TEXT-BOOK OF GYNECOLOGY. The Introduction of Sutures.-I think that on the whole silver wire will be found the preferable suture, although some operators, notably Skene and Simon, have obtained most excel- lent results with the use of silk. The wire is easily introduced, FIG. 87. G.TIEMANN EMMET'S NEEDLES. FIG. 88. SIMS' NEEDLE FORCEPS, WIth Needle. the degree of tension can be controlled perfectly, and it is not readily contaminated. A needle of suitable size and length is a ს FIG. 89. a C grasped with the needle holder at a proper angle. The mucous membrane of the upper edge of the wound is held with a tenac- ulum and the first suture is intro- duced at the angle farthest from the operator. The method of pass- ing the suture is shown in Fig. 89. The needle should extend only as far as the vesical mucous membrane, and not penetrate it. Counter force is made as the needle is passed either with a counter pres- INTRODUCTION OF SUTURes. a. Vesical margin. b. Vaginal mar- gin. c. Point of entrance of needle. d. Point of exit of needle. FIG. 90. G.TIEMANN & CO EMMET'S COUNTER-PRESSURE HOOK. sure hook (Fig. 90) or with a strong tenaculum, so that no URINARY FISTULÆ. 527 undue tension will be exerted upon the tissues. After the wire of the first suture is drawn through, the ends are slightly twisted and handed to the assist- ant who holds the speculum. This suture will now steady the tissues so that the subsequent ones are more readily intro- duced. They should be placed from two- to three-sixteenths of an inch apart, and should extend on the vaginal surface. FIG. 91. TIEMANN & CO SUTURES PASSED. FIG. 92. at least one-quarter of an inch from the edge of the wound. The number of sutures used will, of course, depend upon the size of the opening. At both angles of the wound there should be at least one suture extending beyond the vivified tissue, so as to overcome all tension at these points. Coaptation of the Edges of the Fistula.-After the sutures are all introduced temporary co- aptation is made by drawing to- gether the ends of the silver wire, in order to ascertain whether or not the edges will be perfectly approximated. A soft rubber catheter is now slipped over the end of the irrigating tube and passed into the bladder, through which the bladder is thoroughly washed and freed from all clots before the wound is finally closed. It is best to keep a con- tinuous stream of sterilized water flowing into the bladder until just before the last two or three sutures are twisted, so that no blood may be left behind to give rise to subsequent trouble. The ends of the suture farthest from the operator are TWISTING THE SUTURE. 528 A TEXT-BOOK OF GYNECOLOGY. untwisted, after which one or two turns are given it near the wound in order to coaptate the edges. The suture is now slipped into Sims' shield (Fig. 93) and the loose ends grasped in a wire twister (Fig. 95), when sufficient torsion is made to ap- proximate the edges of the wound. There is always danger of producing too much tension by excessive torsion; the edges of the wound should be simply brought together without any puckering of tissue. If the tension is too great, the suture will cut its way out and the operation will end in failure. Before the wire twister is removed the suture is shouldered by bending it over a tenaculum placed as near as possible to the wound. It is FIG. 93. f SIMS' SHIELD. FIG. 94. G.TIEMANN &CO, GTIEMANN & CO. THE AUTHOR'S SPONGE HOLDER. FIG. 95. FIEMAN THE AUTHOR'S WIRE TWISTER. then cut off so that about half an inch of the twisted wire is left lying flat upon the vaginal surface. Latterly, instead of securing the wire by twisting, I have been using perforated shot almost exclusively for the same purpose. These can be passed over the two ends of the wires and compressed more quickly than it is possible to secure them by twisting; the tension of the wound can be quite as nicely regulated, and there is little danger of the sutures becoming buried in the tissues and lost. I am using the shotted suture more and more in plastic work as time goes on. The lead plates, which were formerly considered necessary when the sutures were secured in this way, I never apply; they are entirely superfluous. URINARY FISTULÆ. 529 After the wound is completely closed, the bladder is again washed through the urethra, all of the water being drawn off. The washing should continue as long as the water is blood tinged. Clots left behind might give rise to severe vesical tenesmus or to obstruction of the urethra. It is, therefore, important to have the bladder perfectly clean before the patient is removed from the operating table. After-treatment.-Most operators advise that a self-retaining catheter be kept in the bladder for several days after the opera- tion. This always gives rise to more or less irritation of the FIG. 96. ท 6.TIEMANN & CO. 貞 ​REMOVAL OF SUTURES. རངས་་ urethra and bladder and seems to me an unnecessary precaution. If the catheter is carefully introduced every four hours there is really no necessity for this precaution, and the results in my hands have been quite as satisfactory as when the instrument has been left permanently within the bladder. After five or six days the patient is permitted to urinate spontaneously if she can do so. Should there be any cystitis left behind after the operation, this should be dealt with according to the method given for cys- titis when resulting from ordinary causes. It is often beneficial 34 530 A TEXT-BOOK OF GYNECOLOGY. FIG. 97. SIMON'S POSITION FOR VESICO-VAGINAL FISTULA. (Simon.) FIG. 98. SUTURES TIED. (Simon.) URINARY FISTULE. 531 to wash the bladder once or twice a day for a week or ten days following the operation. The vagina should be kept perfectly clean by douching it once or twice a day with a 1:3000 bichlorid solution. The diet should be restricted and the bowels kept open. FIG. 99. The sutures are removed in from eight to ten days, although if the silver wire is used they may be left in for a longer period without setting up irritation. They are removed by placing the patient upon her side before a good light and introducing a Sims speculum. The ends of the twisted wire or the perforated shot are seized with a pair of forceps and gentle traction exerted. The point of a pair of wire scissors is then passed beneath the suture, with which it is cut, and the su- ture withdrawn. If there should be any doubt as to the success of the opera- tion, a test can be made by carefully injecting fluid in- to the bladder. It must, however, be borne in mind that at the end of eight or ten days union is not very strong, and by unreason- able distention of the blad- der the edges of the wound may be forced apart. In case of failure, either com- plete or partial, subse- quent operations will have to be resorted to. OPERATIONS FOR VESICO-VAGINAL FISTULA BY FLAP SPLITTING. In the foregoing descrip- (a) Fistula; (6) vesical wall; (c) vaginal wall. tion I have given the tech- (Walcher.) nique as practised by most modern operators. It varies some- what from that practised by Dr. Sims, who first employed the quill suture but subsequently discarded it for the interrupted. Bozeman, Baker Brown, Agnew, Simpson, Simon, and many 532 A TEXT-BOOK OF GYNECOLOGY. others have modified the operation and have special methods of their own. Simon's method is particularly unique and original. Its chief features are:- 1. Substitution of the exaggerated lithotomy position for the semi-prone. 2. Silk is used for suture material instead of silver wire. FIG. 100. 3. The mucous mem- brane of the bladder, es- pecially if it contains much cicatricial tissue, is invaded. 4. The after-treatment is negative. No perma- nent catheter is used and the patient is permitted to urinate spontaneously as soon as she is able to do so. One great advantage of the lithotomy posture is the possibility of using Fritsch's irrigating spec- ulum, which cannot be done in the Sims posture. I found the position ex- ceedingly useful in an operation in which it was necessary to utilize the anterior lip of the cervix in order to close a large fistula which opened high up in the vaginal fornix. Modifications of the Technique.-If the operation is un- usually difficult and the opening large, it may be best to close it at several sittings. It is also recommended that, when the edges of the wound are exceedingly vascular, instead of vivifying the entire surface at once, a small portion only be denuded and immediately closed with sutures. OPERATION FOR VESICO-VAGINAL FISTULA BY FLAP SPLITTING. Schematic figure of the different stages. (Wal- cher.) URINARY FISTULE. 533 The flap-splitting method, now so extensively used in opera- tions upon the pelvic floor and perineum, has also been applied to closing various forms of fistulæ opening into the vagina. Those who especially advocate this method are Tait, Herff, Fritsch, Walcher, and Sanger. Walcher uses catgut for the purpose of uniting the vesical lips; he then closes the vaginal wound with ordinary antiseptic silk. Figs. 99 and 100 show the successive steps of this operation more clearly than it is possible to describe them by words. VESICO-VAGINAL FISTULÆ REQUIRING SPECIAL OPERATIONS. In case of a triangular fistula the wound, when it is closed, will be Y-shaped, whereas a quatrilateral opening will have to be closed by four lines of sutures. Should the fistula be situated close to the cervix, its anterior lip may have to be utilized in or- der to close it. This is done by denuding the edges of the fistula in the usual way and then removing a corresponding strip of mucous membrane from the anterior portion of the cervix, so that the edges of the fistula can be attached to the vivified sur- face of the cervix. In a case of this kind sent to me by Dr. Burk of Centerville, Michigan, there was an opening into the anterior fornix from the bladder through which two fingers could be passed. It required in all twenty shotted sutures to close the opening. The results were perfect. In this case the fistula was caused by long-continued pressure of the fetal head. Should the anterior lip of the cervix be destroyed it will be necessary to close the fistula by utilizing the posterior lip, when the uterus will communicate with the bladder and the menstrual blood will be discharged per urethram. Vesico-uterine fistulæ must be dealt with in one of two ways: First, if possible, the fistula is exposed by splitting the cervix upon either side, when the opening into the uterus is closed in the ordinary way; or, if the fistula cannot be so gotten at, it will be necessary to obliterate the cervical canal and divert the discharges from the uterus into the bladder. Uretero-uterine and Uretero-vaginal Fistula. - These forms of fistula occur so rarely that the reader is referred to special works upon the subject for an extended description of the 534 A TEXT-BOOK OF GYNECOLOGY. methods devised for dealing with them. Four cases were re- ported during the year of 1891. The first two were by Schatz.* He observed that the urine escaping from the ureter had a specific gravity of from 1003 to 1006, while the specific gravity of that passed per urethram was 1030. The urea was entirely absent from the urine coming directly from the kidney and the solid matter in the two urines was as I: 10. Campbellt succeeded in ac- complishing a cure in one case by splitting up the uretero-vesical septum and closing the vaginal surface of the cut. Dr. W. H. Baker of Boston cured a similar case by dissecting up the ureter, making an opening into the bladder near its neck, into which the ureter was turned and the vaginal wound closed. It may be necessary to remove the corresponding kidney, as has been successfully done by Zweifel of Erlangen. A com- pensatory hypertrophy of the opposite kidney usually takes place. Urethral Fistula.-There is ordinarily no difficulty in closing artificial urethral fistulæ made for the purpose of curing or re- lieving abnormal conditions of the urethra. There is, in these cases, no loss of tissue, and the opening is closed by the same methods required for the closure of ordinary vesico-vaginal fis- tulæ. Should there be redundancy of tissue, as is sometimes the case in dilatation of this canal, a sufficient amount may be excised to overcome the existing distortion. The conditions are, however, quite different when the urethra is partially or entirely destroyed by sloughing or ulceration, as occasionally The formation of an entire new urethra constitutes the highest type of plastic surgery. For work done in this direction the profession owes much to Dr. T. A. Emmet, to whose excel- lent monograph on the subject the reader is referred.‡ occurs. During the spring of 1891 I had to do with a case where the urethra and the base of the bladder had been eaten away by syphilitic ulceration. The patient was sent to me by Dr. Bowen of Manistique, Michigan, and had previously been in the hands of Prof. Nicholas Senn of Milwaukee. This distinguished sur- * Medical Press and Circular, London, August 5, 1891. † Virginia Medical Monthly, April, 1891. "Vesico-vaginal Fistula," 1868. URINARY FISTULÆ. 535 geon had, by three operations, succeeded in entirely restoring the base of the bladder. The patient could retain her urine for a short time by placing against the opening a tampon of cotton. The tissues beneath the pubes had been greatly destroyed by the ulcerative process. I succeeded by the following method in making a new urethra: Two parallel surfaces about three six- teenths of an inch wide, and extending from the natural site of the meatus to the opening just beneath the arch of the pubes, were vivified. An unscarified strip about half an inch in width was left between them, to form the tract of the new urethra. In order to approximate the two vivified surfaces it was neces- sary to overcome the tension by making parallel to, and outside of, each denuded line an incision into the mucous membrane. At the point of the opening into the bladder the vivified sur- faces were shaped in such a way as to adapt themselves to the denuded edges of the fistula. The edges were next approxi- mated by silver wire sutures over a small sized glass catheter, which was kept in situ for seven days. The stitches were then removed, but owing to the excessive tension (the width of the unscarified surface should have been greater) the edges of the wound corresponding to the middle third of the canal had not healed. By a subsequent operation this opening was closed, but the parts again separated sufficiently to leave a pin-head fistula, which, however, does not leak urine. While the patient now has very much better control of the bladder, the results are not entirely satisfactory. She can retain the urine for two or three hours, though it is still necessary to keep within the vagina a tampon in order to press against the canal. Of course, the vesical sphincter was entirely destroyed by the ulcerative pro- cess and can never be restored. She is coming to me for another operation and I shall undertake to narrow the canal at the vesi- cal neck, hoping thereby to improve the retaining power of the bladder. Closure of the Vagina: Kolpokleisis.-This is an operation which, happily, with the conquests of modern plastic surgery, is rarely called for. Cases will, nevertheless, occasionally be met with in which it is utterly impossible, because of the excessive loss of tissue, or because of the changes within the vagina, to 536 A TEXT-BOOK OF GYNECOLOGY. cure the fistula. Under these circumstances, in order to place the patient in as comfortable a condition as possible, the vagina will have to be closed. This operation is known as kolpokleisis. The operation, as performed by Simon, consists of vivifying transversely the walls of the vagina above the level of the ostium vaginæ and bringing the denuded surfaces together with silver wire sutures. Vidal de Cassis, who first introduced it, vivified the inner surfaces of the labia majora and brought them together by sutures. In the latter method the vulva is closed in an an- tero-posterior direction, and there is necessarily a cleft below the urethral orifice, through which the urine escapes; consequently, it is useless. Simon's method is as follows: The mucous membrane is picked up with tenacula at a point where it is most lax; the point selected should be as high as possible. The ring of tissue to be removed is next outlined with the point of a scalpel, when it is dissected from below upward with a pair of curved scissors. It can ordinarily be removed in one continuous strip. The sutures are introduced from above downward, i. e., carried underneath the vaginal wound above and reintroduced upon the inner border of the vaginal wound below, being brought out at its outer edge. Care must be observed that neither the bladder, the uterus, nor the rectum is injured by the needle. After all of the sutures are introduced they are secured either with per- forated shot or by twisting. By this operation the bladder and the vagina permanently connect with each other, and all of the discharges from the uterus are made to pass through the urethra. This unnatural state will necessarily give rise to more or less discomfort and the operation is, therefore, never performed except as a last resource. Owing to the fact that there will be more or less urine retained within the vagina, there is danger of the formation of urinary concre- tions. Usually, however, the patient is infinitely more comfort- able than she would be were she compelled to go through life constantly wet by the urinary discharge. CHAPTER XXXV. FECAL FIstulæ. Fecal fistulæ do not occur so often as do the urinary. When they do occur they are, because of the incontinence of feces and gas, more distressing than are fistulæ giving rise to inconti- nence of urine only. Varieties. These are recto-vaginal, recto-labial, entero- vaginal, and entero-vesical. The frequency of these several varieties is in the order given. The causes are much the same as those responsible for uri- nary fistulæ, prolonged pressure and injuries during childbirth being the most frequent cause. Cancerous and syphilitic ulcer- ation oftener involve the posterior than the anterior vaginal wall. Other causes are: direct injury, improperly fitted pessaries, stricture of the rectum with retention of fecal matter, and ab- scess of the recto-vaginal wall. RECTO-VAGINAL FISTULÆ. These are divided into recto-vulvar, inferior recto-vaginal, and superior recto-vaginal, according to their situation. They vary in size from an opening barely large enough to admit a fine probe to one through which one or more fingers can be passed. Those situated in the posterior vaginal cul-de-sac are especially liable to be large. The edges are usually clearly defined, and are hard and unyielding. Symptoms and Diagnosis.-The patient will first be made conscious of the existence of the fistula by the escape of fecal matter and gas through the vagina. The amount of fecal mat- ter which escapes in this way will depend upon the size of the opening through the recto-vaginal wall, and upon the direction of the fistula. If oblique, it may give rise to trouble only when there is diarrhea. The existence of these symptoms will at once suggest a fecal fistula and will call for an examination. 537 538 A TEXT-BOOK OF GYNECOLOGY. Physical Signs.-In order to detect the opening the patient should be placed upon her back in the lithotomy posture and the posterior vaginal wall exposed. This can be done either by means of the blade of a small-sized Sims speculum passed from above, or, better still, by the introduction of an expanding bivalve rectal speculum. If the opening is at all large its loca- tion will be readily seen; if very small, on the other hand, it may be necessary to inject into the rectum milk or some col- ored fluid and watch for its appearance through the vagina. Sometimes when there is much relaxation of the ostium vaginæ air will pass into the vagina when the patient lies upon her side, and its expulsion will give rise to suspicions of a fecal fistula. The only way of determining positively whether or not the air escapes from the bowel into the vagina is by physical ex- ploration; there would, of course, be no odor attending the ex- pulsion of flatus which finds its way into the vagina through its ostium. Prognosis. The prognosis, as in urinary fistula, will depend both upon the size of the opening and its location. Those most easily dealt with are located above the sphincter ani mus- cle; those most difficult to contend with are located near the perineum and involve this muscle. If the vagina is distorted by cicatrices, the difficulty of accomplishing a cure is much in- creased. Treatment. It is sometimes possible to cure very small recto-vaginal fistula by cauterization. An attempt should be made to do this before subjecting the patient to an operation. However, if the opening is of some size, the only resource is denudation and coaptation with sutures. Wound infection, because of fecal contamination, occurs much oftener than is the case with urinary fistulæ. The operation may be performed through the vagina or the rectum, or by flap-splitting through the perineum. Operation through the Vagina.-The cases especially suit- able for this procedure are those not complicated by cicatrices. The bowels should be thoroughly emptied by purgatives, and an hour or two before the operation the lower bowel should be washed with an enema, followed by a saturated boracic acid FECAL FISTULE. 539 solution. The usual methods of cleansing the vagina are to be observed. The posterior vaginal wall is now exposed by placing the patient in the lithotomy posture and opening the vagina with a Fritsch speculum introduced under the pubes. Lateral retractors more thoroughly expose the field of operation. The edges of the fistula are next denuded according to the method recommended for vesico-vaginal fistula. The denuda- tion may or may not extend into the rectal mucous membrane, depending upon circumstances. Ordinarily, I think it is best to go deep enough to include this membrane. The sutures are passed in such a way as to include all of the tissues of the posterior vaginal wall, unless the rectal mucous membrane has not been denuded; in the latter event they extend only down to it. The sutures are secured either by twisting or by per- forated shot, as the operator may prefer. In making the denudation and in introducing the sutures, the direction of the suture line should be such as to produce the least amount of traction upon the tissues when the sutures are secured. In very large fistulæ this will oftener be transverse. Operation through the Rectum. - As regards preparation, the precautions given for the vaginal operation should be observed. After the patient is placed in the proper position the sphincter muscle is paralyzed by forcible divulsion. The rectal cavity is next exposed by a suitable speculum, or by the blades of two small Sims's specula. The denudation should extend for some distance into the rectal mucous membrane, and should include that of the vagina as well. The sutures are passed from the rectal side, penetrate the vagina about half a centimeter from the edge of the wound, and are reinserted the same distance. upon its opposite side, making their appearance at a correspond- ing point in the rectum. They may, however, be passed from the vaginal side. If the latter method is resorted to, silver wire may be used; whereas if the sutures are secured through the rectum, silk is the preferable material, because of the diffi- culty attending the removal of silver wire from this canal. Perineal Operation.-The perineal method is especially adapted to fistulæ situated near the perineum within the grasp of the sphincter muscle. When so situated it is difficult to · 540 A TEXT-BOOK OF GYNECOLOGY. overcome the spasmodic tendency of the sphincter muscle by divulsion alone. It is, therefore, necessary to cut entirely through the perineal body, or what is left of it, when the condi- tion is treated as a complete laceration of the perineum extending upward into the vagina. It can be closed either by the flap- splitting method, or by the older one of uniting the upper and lower edges of the wound with interrupted or with continuous sutures. Personally, I prefer the flap-splitting method. After-treatment.—The patient is placed in bed and kept perfectly quiet until the sutures are removed-at the end of eight or ten days. The diet should be light and the bowels confined for the first four days by administering a small dose of opium. On the evening of the fourth day they are moved by a cathartic and the lower bowel carefully emptied with an enema. They are again confined for forty-eight hours, at the end of which time they are moved as before. If the metallic sutures are used, they can be left in for an almost indefinite length of time, though it is usually best to remove them at the end of the tenth day. Silk sutures should not be left in longer than eight days. RECTO-LABIAL FISTULEÆ. In this variety of fistula the opening, instead of extending into the vagina, finds its way through one or the other labium. In order to cure it, it is necessary to lay the canal freely open and destroy the sinus, either by dissecting it out entirely or by curetting and closing the tract from the bottom. If practicable, the sinus should be closed by the buried catgut suture; if not, it should be packed with gauze and permitted to heal by granula- tion. ENTERO-VAGINAL FISTULÆ. The usual cause of these fistulæ is extensive destruction of tissue attending childbirth, there being left an opening into the peritoneal cavity through one of the fornices of the vagina. A loop of intestine may find its way into this opening and become strangulated, giving rise to fistula. This accident may also attend suppurating extra-uterine pregnancy and dermoid cysts. Can- cerous ulceration sometimes perforates the peritoneal cavity and FECAL FISTULÆ. 541 may likewise give rise to entero-vaginal fistula, though the condition is rarely due to this cause. Symptoms and Diagnosis.-If the opening is large, all of the fecal matter will pass through the vagina and none through the rectum. It is easily detected upon digital examina- tion and can readily be seen by the introduction of a speculum. If the discharge proceed from the small intestine, it will be of a liquid character and of a greenish or yellowish color. If, on the other hand, the connection is with the large bowel lower down, it will be more solid and more characteristically fecal in every way. Treatment. It will be necessary to close the opening through the vagina, as it cannot be reached through the rectum. If small, an attempt may be made to close it by cauterization, a method which will often be successful; if, however, the open- ing is large, and all of the fecal matter passes into the vagina, the only resource is laparotomy and resection of the intestine. Before doing this the operator must make sure that the rectum and lower bowel are pervious. Should this operation fail, or should the patient decline to submit to it after a full understanding of the dangers attending it, kolpokleisis may be performed. Before the vagina is closed, however, it is necessary to make a communication between it and the rectum below the fistula. The opening is best made by compressing the recto-vaginal septum in the jaws of long curved forceps, one blade of which is passed into the vagina and the other into the rectum. The compression is continued long enough to produce adhesions and to create a slough. After the slough comes away an opening sufficiently large to permit the fecal matter to pass from the vagina into the rectum is created. Kolpokleisis is then performed according to Simon's method, which is described in the preceding chapter. ENTERO-VESICAL FISTULÆ. Suppuration within the pelvis, from whatever cause, may give rise to a communication between the intestine and the bladder. This is exceedingly rare, but cases of the kind are occasionally recorded. The amount of suffering caused by it will depend 542 A TEXT-BOOK OF GYNECOLOGY. upon the size of the opening and the portion of the bowel which connects with the bladder. When air finds its way into the bladder the condition is known as pneumaturia. Should the opening be small and the inconvenience not great, the physician will hardly be justified in subjecting the patient to an abdominal section or to suprapubic cystotomy for the purpose of closing it. Should, unfortunately, the opening be large, the urine will be contaminated by fecal matter, which will very soon give rise to cystitis and renal disease. Here the wretched condition of the patient will warrant either laparotomy or suprapubic cystotomy; or, if these be impracticable, high colotomy. The site of the in- testinal opening can be surmised by the character of the discharge which finds its way into the bladder and is passed per urethram. Should the connection be with the large intestine low down, this fact may be determined by injecting milk into the bladder and watching for its appearance through the rectum. CHAPTER XXXVI. DISPLACEMENTS OF THE UTERUS. General Considerations.-In dealing with uterine displace- ments it must be borne in mind that the uterus is a movable organ. This fact has given rise to much discussion as to its normal position. The fundus is pushed forward by a distended rectum and backward by a distended bladder; the entire organ is made to descend by intra-abdominal pressure, and is elevated during coitus. The displacements resulting from a distended bladder are well shown in Fig. 101. It will be seen that, with the bladder empty, the axis of the uterus is very nearly at a right angle with the axis of the vagina; the fundus rests upon the bladder and is close to the symphysis pubis. The body, because of the rectum, is slightly deviated to the right and is bent more or less forward; the cervix is directed backward. The uterus is supported by— Uterine ligaments; Intrapelvic areolar tissue and pelvic walls; Supporting power of the abdominal walls; Upper part of vagina. The varieties of displacement which present themselves for consideration are:— 1. Anteversion, in which the fundus is directed unnaturally forward and the cervix unnaturally backward; the normal uterine curve is less pronounced. 2. Anteflexion, in which the normal curve is increased; the direction of the cervix is but little changed. 3. Retroversion, in which the fundus is directed backward and the cervix forward. 4. Retroflexion, in which the uterus is bent upon itself, so that its normal curve is reversed; the direction of the cervix is normal or nearly so. 1 543 544 A TEXT-BOOK OF GYNECOLOGY. 5. Lateroversion, in which the uterus is drawn to one side. 6. Displacement of the uterus as a whole-retroposed. This may result from pelvic tumors or from inflammatory adhesions. 7. Prolapse, usually associated with more or less prolapse of the vagina. FIG. 101. VARIATIONS OF THE POSITION OF THE UTERUS CAUSED BY THE VARIOUS DEGREES OF BLADDER DISTENTION. 8. Ascent, the result of traction from above (ovarian and fibroid tumors). 9. Inversion. Rarely does one form of displacement exist alone. Thus, anteversion and anteflexion are always combined, as are retro- DISPLACEMENTS OF THE UTERUS. 545 version and retroflexion. More or less descensus is usually associated with the retro-displacements, and a slight lateral dis- placement is frequently combined with the other forms. ETIOLOGY. The causes of the several forms of uterine displacements are numerous. Any condition or disease giving rise to increased weight of the organ tends to produce displacement. Such are the various forms of inflammation-acute and chronic-subinvo- lution, tumors, pregnancy, etc. The natural supports of the uterus are diminished by relaxa- tion of the uterine ligaments, injuries to the perineum and pelvic floor, flabby and over-distended abdominal walls, and an abnor- mally large pelvis. The causes acting from above are :— Increased intra-abdominal pressure, the result of pelvic and abdominal tumors or ascites; Constriction of the waist by improper clothing; Straining or lifting ; Undue distention of the bladder and colon. Pelvic inflammation, giving rise to distortion of the pelvic organs in general, may cause any of the forms of uterine dis- placement. When resulting from inflammatory exudates, the displacement is at first due to the mechanical pressure of the exudate, and, later, to its retraction. Thus an exudate in the right broad ligament will primarily push the uterus to the oppo- site side; after retraction occurs the fundus will be drawn toward the side of the exudate. Anteversion and anteflexion are fre- quently caused by retraction of the utero-sacral ligaments-the sequelae of previous inflammation. SYMPTOMS. The symptoms characterizing the special displacements will receive due attention later on. A few general considerations are worthy of notice at this time. I have elsewhere called attention to the fact that uterine dis- placements are ordinarily attended with no distress unless asso- 35 546 A TEXT-BOOK OF GYNECOLOGY. ciated with hyperemia or hyperesthesia.* That is to say, save in acute cases which are the result of traumatism, uterine displace- ments will and frequently do exist for an indefinite period without giving rise to the least discomfort. This is especially true of congenital anteversion and anteflexion-so emphatically so that some eminent authorities deny that these displacements ever require treatment. It is an indisputable fact that many women go through life with the various forms of displacement without being conscious of their existence. If married they may have been sterile, but for this symptom they have never submitted to a local examination. In the larger number of cases, however, either hyperesthesia or hyperemia, or both combined, are sooner or later developed. Then a train of symptoms, more or less intense, succeeds. These symptoms are by no means constant nor are they pathog- nomonic. The hyperemia, after continuing for a certain length of time, usually gives rise to hyperplasia and chronic metritis. The increased weight resulting from the uterine congestion aggravates the displacement, in whatever form it may be. In this way the uterus is "blood-logged," as it were, and asso- ciated with the displacement there is usually more or less. prolapse. As time goes on the mucous membrane undergoes hypertrophy, which in turn establishes menorrhagia or metror- rhagia. Dysmenorrhea is likewise a frequent symptom of uterine displacement, especially of anteflexion. It is due both to ob- struction and to the congestion and hyperesthesia incident to the displacement. Instead of excessive menstruation there may be amenorrhea, particularly in congenital anteflexions. As already intimated the cervical stenosis, which is an essential feature of flexion, is one of the most common causes of sterility. Dyspar- eunia also results in a goodly number of cases. All forms of displacement may give rise to distress upon locomotion. Sacral and lumbar pain and reflex pains in various parts of the body are of common occurrence. In perimetritis, salpingitis, etc., the uterus is usually fixed by adhesions. It will thus be seen that the symptoms of uterine displace- * v. Chapter viii. ANTEVERSION AND ANTEFLEXION. 547 ment, when such symptoms exist, are general rather than specific; and that they may be entirely wanting. It will not do, therefore, to undertake the erection of a special uterine pathology based upon displacements, as has actually been attempted by Hewitt and others; nor will it do to ignore the importance of uterine displacements because in a goodly number of cases no inconve- nience follows in their train. ANTEVERSION AND ANTEFLEXION. In anteversion the womb is tilted forward without any bend in its axis; in anteflexion it is not only tilted forward but it is also bent upon its axis. its axis. These two conditions are frequently of con- genital origin. Any of the symptoms which have been enumer- ated may result from either form of displacement. Since, how- ever, they are oftener congenital it is hardly wise to exaggerate their importance. The physician is liable to attribute to them, if he can discover no better cause, symptoms which are in reality due to nerve exhaustion, irritable spine, congestion of the ovary, etc. It is well, to be sure, to look to the displacement when an intractable dysmenorrhea or amenorrhea exists. So, too, if rectal and vesical tenesmus, especially the latter, do not yield to ordinary treatment. I have in another place (page 68) referred to the importance of looking for antedisplacement, particularly when the result of shortening of the utero-sacral ligaments, when there exists an obstinate dysuria which is clearly not due to in- flammation of the bladder or urethra. Ovarian congestion and ovaritis may result from the embarrassed uterine circulation. Diagnosis. In anteversion digital examination will reveal the cervix in the hollow of the sacrum, and directed more posteriorly than normal. The finger will detect in the anterior fornix the fundus uteri, which is continuous with the cervix. Upon bi- manual examination the entire organ can be gotten between the two hands and clearly outlined. There is no sulcus just behind the internal os, as in anteflexion. Should doubt still exist, after the possibilities of pregnancy are eliminated, the uterine sound may be used. The introduction of this instrument will require some tact because of the backward displacement of the cervix. If necessary the cervix can be drawn down with the volsella or } 548 A TEXT-BOOK OF GYNECOLOGY. tenaculum, which will facilitate its introduction. No force should be attempted in passing the sound. The handle will have to be carried well back and the instrument given various degrees of curvature before it will penetrate the uterine cavity. By the aid of the sound it is usually possible to distinguish an antedisplaced fundus from a small fibroid tumor, or inflammatory deposits in the anterior cul-de-sac (Fig. 102). In anteflexion the fundus is felt more distinctly in the anterior fornix than is the case in anteversion. The cervix, instead of DOD FIG. 102 ANTEVERSION OF THE UTERUS. E. G. being directed backward, is directed downward and even forward. By sweeping the finger along its anterior surface there will be felt a sulcus separating the body from the cervix. Occasionally the cervix at the point of flexure is drawn so far anteriorly as to give rise to a condition resembling partial retroversion or retroflexion. The uterus may be low in the vagina. The sound will have to be bent much more acutely in order to pene- trate the uterine cavity than is the case in simple version. It is ANTEVERSION AND ANTEFLEXION. 549 necessary to give to the instrument a curve corresponding to the degree of flexion before it can be passed. By it the location of the fundus can be determined, as well as its mobility and sensi- tiveness (Fig. 103). By practising the bimanual with the sound in the uterus the examiner can also satisfy himself that the tumor in the FIG. 103. ANTEFLEXION OF THE UTERUS. A half-section of the pelvic viscera of a sterile woman, aged 33. The uterus is small, with its body considerably anteflexed on the cervix, which is very short, the vaginal portion hardly existing, so that the Douglas cul-de-sac lies below the os externum. The bladder coats are hypertrophied. The cervix is drawn back- ward by contraction of the utero-sacral ligaments. (Museum R. C. S., Photo- graphed by the Author.) anterior fornix is not a small fibroid. Should there be diffi- culty in passing the instrument, the axis of the uterus can be straightened, as in anteversion, by drawing the cervix down- ward with the volsella; or by pushing the fundus upward through the anterior vaginal fornix. Before the examination is concluded it is well to carefully 550 A TEXT-BOOK OF GYNECOLOGY. 1 explore the vaginal roof for the evidences of adhesions, con- stricting bands, or inflammatory effusions. The mobility of the uterus should always be ascertained before an attempt is made to reposit it with the sound. Anteversion and anteflexion are so inseparably blended that I have deemed it wise to consider the two affections conjointly. In most cases anteversion precedes anteflexion, and often neither condition is suspected until after marriage, when the patient may find herself sterile. In dealing with dysmenorrhea in young girls these two forms of displacement, as possible causes, should always be borne in mind. TREATMENT. It is by no means necessary to treat all, or even a majority, of cases of antedisplacement. Certainly no treatment is called for unless distressing symptoms exist. The principles of treatment are the same in both forms, though it is more difficult to overcome anteflexion than anteversion. In either variety the deformity is less easily corrected than is the case with retrodisplacements. In order to elevate the fundus with a pessary it is necessary to exert more or less pressure through the bladder. This will frequently give rise to distress, and many times the patient can better tolerate the disease than the treatment. In all instances the cause should be removed if possible. This implies the adoption of proper clothing,—all constrictions about the waist being overcome,—the relief of pelvic congestion due to constipation or irregular sexual habits, the removal of inflam- matory exudates by proper treatment, and the stretching, if contracted, of the utero-sacral ligaments by uterine massage and pressure exerted by tampons. A certain amount of preparatory treatment is usually necessary before a pessary is fitted. This consists in the application of those measures having for their object the relief of pelvic con- gestion and inflammation. The hot douche, the medicated tampon, and proper rest will afford much relief. It is not only useless but dangerous as well for the patient to undertake to wear a pessary while suffering from pelvic inflammation, even of a ANTEVERSION AND ANTEFLEXION. 551 chronic type. Properly applied tampons placed in the anterior vaginal fornix will so elevate the fundus and the uterus as to afford marked temporary relief. After the parts are prepared by this treatment a pessary may be fitted. While the patient is undergoing preparatory treatment an effort should be made to straighten the uterus. This may be done either by the bimanual or by the use of the uterine sound or repositor. If done according to the former method, the fundus is lifted by pressure exerted through the anterior fornix and by drawing the cervix toward the symphysis. Should there be no adhesions but little difficulty will be experienced in repositing the uterus in this way. On the other hand if the utero-sacral liga- ments are contracted, or if the fundus is attached in front by adhesions, it will be impossible to correct the displacement. However, repeated attempts to do so, care always being observed not to use undue force, will in time stretch the adhesions suffi. ciently to make reduction possible. This is a form of uterine massage which, if intelligently applied, may result in much good. When the reposition is made by means of the uterine sound, the instrument should be introduced as far as the fundus and curved sufficiently to insure its introduction. The finger of the left hand should now serve as a fulcrum at the center of the sound, when the handle is carried forward toward the symphysis, the fundus being thus retroverted. Finally the sound is carefully rotated (v. p. 108) and a slight retroflexion induced. Of course no attempt should be made to reduce the displacement by means of the sound if the uterus is fixed by adhesions. Various forms of uterine repositors have been devised for this especial purpose, but none is superior to the uterine sound if skilfully used. Pessaries in Antedisplacements.-Undoubtedly pessaries in all forms of displacement have been used much too often. This fact has led some writers to make a sweeping condemnation of them, especially in antedisplacements. Ingenuity and mechani- cal skill are essential requisites in fitting pessaries. Without these much harm may be done. If the physician possesses these qualities he will be able, in all forms of displacement, to do much 552 A TEXT-BOOK OF GYNECOLOGY. good with pessaries. However, to obtain the best results careful discrimination is necessary. No two cases can be treated in exactly the same way. A pessary must be selected that will lift the body of the womb by pressure exerted through the anterior fornix without injuring the bladder, at the same time drawing the cervix forward by obliterating the utero-vesical pouch. For this purpose the most frequently employed pessaries are Gehrung's, Hewitt's, and Thomas's. Gehrung's is simply a Hodge pessary doubled upon itself. Its two lateral curves rest on the floor of the pelvis, while its superior and inferior arches impinge upon the anterior vaginal fornix, between the fundus uteri and symphysis. This is the manner in which it is used by Mundé, and is, I believe, the preferable way of insert- ing it. Gehrung himself fits it so that it rests "with its whole. FIG. 104. FIG. 105. EMANN.CA TIEMANN-CO GRAILY HEWITT'S ANTEVERSION PESSARY. THOMAS'S ANTEVERSION BUCKLE PESSARY. lower arch on the floor of the pelvis, the uterus reclining against its superior curve." My observation leads me to believe that even if the instrument is introduced, as recommended by Gehrung, it will in nine cases out of ten assume the position described by Mundé. In this position it does not interfere with coitus. Graily Hewitt's anteversion pessary is shown in Fig. 104. One point of it rests on the vaginal floor near its entrance, and one high up behind the cervix uteri. Its apex presses the ante- rior vaginal fornix upward, thus elevating the fundus both by direct pressure and by shortening the anterior vaginal wall. This pes- sary is made in three sizes, and will sometimes afford relief when other instruments fail in their object. ANTEVERSION AND ANTEFLEXION. 553 Thomas's anteversion buckle pessary is very popular (Fig. 105). It is a modification of Hodge's lever instrument. The pessary is introduced closed, and as the upper arch approaches the cervix the posterior bar is directed into the posterior fornix, while the anterior bar is pushed forward by the finger. The displacement is overcome by the uterus riding between the posterior and the mov- able bar. Fig. 106 represents Thomas's open cup anteversion pessary. It is introduced with the movable bar extended. This bar is then thrown forward and the uterus rests in the concave portion of the cup. FIG, 106. GJIEMANN & CO THOMAS'S OPEN-CUP ANTEVERSION PESSARY. Stem pessaries, while the only ones that really overcome the flexion, are too dan- gerous to be resorted to except after divulsion; the patient is then kept absolutely at rest for at least a week. For this purpose I use Cleveland's glass plug. (v. p. 270.) The benefit derived from the use of vaginal pessaries in flexions is due quite as much to the elevation of the entire uterus, thus relieving the embarrassed circulation, as to the straightening of the organ. Whatever form of vaginal pessary is selected there are certain dangers to be borne in mind. When left in the vagina for a long time uncleaned they become incrusted with calcareous matter, and may set up serious ulceration, and even bury themselves in the tissues. Cellulitis and metritis have more than once resulted from their use. No pain should result from a properly fitted pessary. This fact should be impressed upon the patient and she should be instructed to have it removed at once should pain occur. This precaution will largely remove the element of danger. Frequent cleansing douches are to be advised. The proper size of the pessary is to be determined by the shape and capacity of the vagina. It is better to run the risk of selecting too small an instrument than to insert one too large. After its introduction the patient should be directed to walk across the room once or twice, after which an examination should be made in the upright posture. If the pessary has turned it is too small, and a larger one should be substituted. (v. p. 560.) 554 A TEXT-BOOK OF GYNECOLOGY. RETROVERSION AND RETROFLEXION. We have seen that physiological retroversion of the uterus occurs whenever the bladder is distended. The displacement becomes pathological only when the fundus remains persistently directed toward the hollow of the sacrum. When the body of the uterus becomes bent upon itself so as to form an angle, flexion is added to the version. It is, then, entirely possible to have a retroversion without a flexion; on the other hand, a retroflexion is always combined with version, the latter in nearly all instances preceding the former. Etiology. The predisposing causes are those of uterine dis- placements in general. The exciting causes are: increased intra- abdominal pressure and diminished uterine support; increased uterine weight from congestion, tumors, etc.; and traction upon the uterus from below. It will be observed that the various exciting causes are those which are associated with and attend parturition. Injuries to the pelvic floor, subinvolution, and chronic metritis all tend to congest the uterus and to increase its weight. If, now, the fundus is crowded into the hollow of the sacrum by a tightly applied obstetric bandage, a retrodisplacement is almost certain to result. Unlike antedisplacements, retroversion and retroflexion occur much oftener in women who have borne children. Pathology. The size of the uterus is nearly always increased because of the embarrassed circulation, and not infrequently there is chronic inflammation of both its par- enchyma and its lining membrane. The fundus finds its way into the pouch of Douglas, and in marked retroflexion may depress this pouch as far as the pelvic floor; it is also in contact with the anterior surface of the rectum. The external os is patulous, and in women who have borne children the cervix is usually more or less lacerated. The anterior surface of the broad ligaments looks backward and downward, while the utero- sacral ligaments are stretched by the cervix being directed anteriorly. Not infrequently one or both ovaries are displaced with the uterus and may find their way into the posterior cul- de-sac. The ureters may be so compressed as to give rise to RETROVERSION AND RETROFLEXION. 555 dilatation.* The bladder is not so markedly affected as it is in antedisplacements. If the displacement is the result of, or has been followed by, pelvic inflammation, the fundus is usually fixed by adhesions. Symptoms. These, as in antedisplacements, may be entirely wanting, or of the most marked character. Probably the most constant symptom is a feeling of weakness and pain in the back, especially after being upon the feet for some time. Other mani- festations of the displacement are caused by the congestion and inflammation resulting from the embarrassed circulation. There is a sensation of bearing down and heaviness in the pelvis with more or less rectal tenesmus. Constipation and hemorrhoids may likewise result from rectal pressure. Menorrhagia and leucorrhea, due to endometritis, are not infrequently present. Any of the so-called "hystero-neuroses" may develop. Dys- menorrhea is much less common than in antedisplacements for the reason that the cervical canal is usually increased instead of diminished in caliber. Pelvic pain due to pressure upon the nerves is often most distressing and not infrequently ex- tends to the lower extremities. Dyspareunia, sterility, and uterine colic are symptoms of less constant occurrence. When conception does take place abortion frequently results. Diagnosis. In retroversion the cervix will be found lower than normal in the vagina and directed forward. By carrying the finger along the posterior surface of the uterus no sulcus can be felt, as in retroflexion. The bimanual will fail to locate the fundus in front. The uterine sound will determine the direction of the canal. * I have at the present time under observation a most interesting case in which obstruction of the ureter was evidently caused by the pressure of a retroverted fundus. The patient was referred to me by Dr. S. A. Boynton of Cleveland. For years she had suffered from attacks of intense pain in the region of the right kidney. During these attacks a tumor of some kind formed, which resembled in every particular an enlarged floating kidney. It formed quickly, becoming fully as large as a fetal head, and then subsided quite as quickly, after which the quantity of urine was markedly in- creased. For the last year these attacks occurred as often as once or twice a week, and were usually brought on by undue exercise. On bimanual the uterus was found retroverted and enlarged. I fitted a Hodge pessary nine weeks ago, since which time she has remained perfectly well. Whether or not permanent relief has been obtained remains to be seen. 556 A TEXT-BOOK OF GYNECOLOGY. In retroflexion the cervix may be normally located; it is usually, however, lower in the pelvis than it should be and looks directly downward. In the posterior fornix the fundus of the uterus will be felt as a rounded body separated from the cervix by a sulcus. The bimanual shows the fundus absent in front. The sound will require a sharp posterior curve in order to insure its introduction. In both forms of retrodisplacement the fundus can be felt through the rectum; it is, however, lower down, and more readily palpated in retroflexion. The several affections giving rise to a tumor in the cul-de-sac of Douglas, and hence liable to be confounded with the retro- displacements, are:- Prolapsed ovary or a small ovarian tumor; Small myoma in posterior uterine wall; Inflammatory exudates; Fecal accumulation. In none of the foregoing affections will the sound penetrate the tumor, as it will in the case of a retrodisplaced fundus. Other differentiating points will be considered seriatim. Prolapsed Ovary or a Small Ovarian Tumor.-A prolapsed ovary is exquisitely sensitive and pressure upon it gives rise to a peculiar sickening pain. It is much smaller than the fundus uteri and, unless adhered, more mobile. When a small ovarian tumor occupies the cul-de-sac of Douglas the fundus will be found in front. Small Myoma in Posterior Uterine Wall.-Bimanual should be practised with the sound in the uterine cavity. The presence of the tumor can then be detected by digital examination per rectum. The fundus is directed forward. Inflammatory Exudates.-The uterus is more or less fixed. There is a history of preceding inflammation. Fecal Accumulation.-This pits upon pressure. In case of doubt the rectum should be emptied. Prognosis. In considering the prognosis of retroversion and retroflexion of the uterus it is necessary to note the presence or absence of adhesions, the duration of the displacement, and also the presence or absence of such complications as prolapse of the ovaries, chronic metritis and salpingitis, injuries resulting from RETROVERSION AND RETROFLEXION. 557 parturition, etc. In uncomplicated retroversion the uterus can usually be restored to its normal position by a properly fitted pessary. Flexions are more difficult to contend with, though by partially overcoming the displacement and elevating the entire organ marked relief is often afforded. As a last resort, some of the operations presently to receive consideration may be utilized. FIG. 107. RETROVERSION OF THE UTERUS WITH A VERY SLIGHT DEGREE OF FLEXION. (Museum R. C. S., Photographed by the Author.) Treatment.-The same preparatory measures recommended for antedisplacements are necessary. No attempt should be made to reposit the uterus if acute pelvic inflammation is present. When the fundus is fixed by inflammatory adhesions, these may be cautiously stretched by pelvic massage. If a cervical lacera- tion is perpetuating the uterine congestion it should be repaired. 558 A TEXT-BOOK OF GYNECOLOGY. Injuries to the pelvic floor are likewise to be overcome by proper operative procedures. Frequent reposition of the uterus previously to fitting a pes- sary will do much good. It may be accomplished by one of the three following methods:- 1. Bimanual Recto-vaginal Manipulation.-With the patient in the dorsal or Sims posture the fundus is pushed forward with the finger of one hand in the rectum, while the cervix is drawn backward with the finger of the other hand in the vagina. 2. Genu-pectoral Posture.-In this position intra-abdominal pressure is reduced to a minimum and gravity alone may carry the fundus forward. It is, however, usually necessary in addition to push the fundus upward either through the vagina or rectum; or to pull the cervix downward, so as to permit the fundus to FIG. 108. FIG. 109. 32 HODGE'S CLOSED LEVER PESSARY. 1.TIEMANN & CO. THOMAS'S RETROFLEXION PESSARY. escape from the hollow of the sacrum. As a palliative measure the genu-pectoral posture practised for five minutes twice a day will often do much good. 3. The Uterine Sound or Uterine Repositor.-Care must be ob- served not to exert too much force with these instruments. The sound should be used as straight as possible and cautiously turned within the uterus. (v. p. 108.) Retention by Means of Pessaries.—Retrodisplacements can be much more readily overcome by means of a pessary than can antedisplacements. This is because injurious pressure is not exerted upon the neighboring organs when the posterior vagi- nal wall is stretched. The principle of a retroversion pes- sary, such as the Hodge, is this: The posterior vaginal wall is carried upward by the instrument and its upper bar gives a RETROVERSION AND RETROFLEXION. 559 point d'appui to the posterior fornix. This draws the cervix back- ward and throws the fundus forward, just as do the utero-sacral ligaments normally. This will not overcome the flexion, but by elevating the entire organ, as already observed, the obstructed circulation is often so much relieved as to do much good. FIG. 110. The intra-vaginal, retroversion and retroflexion pessaries most frequently used are Hodge's (Fig. 108), Thomas's (Fig. 109), and Albert Smith's (Fig. 110). It will be observed that the principle is the same in all. The original Hodge pessary was as wide at its lower extremity as at its upper. Smith's modification con- sisted of narrowing the lower end so as to conform to the shape of the vagina. This is a valuable improvement. Thomas's modification the upper bar is made bulbous and the sacral curve is exag- gerated. In certain cases it can be tolerated when the other forms cannot be. In G.TIEMANN & CO ALBERT SMITH'S PESSARY. These pessaries are now made almost altogether from vulcanite, which is light and unaf- fected by the vaginal discharges. The application of heat renders them flexible, and it is therefore possible to mold them into any desirable shape. This is done as follows: Place the pessary in hot water; leave for five or ten minutes; remove and mold into the shape desired and then set by immersing in cold water. It may be molded by first smearing the pessary with vaselin and then heating it over a spirit lamp. When the latter method is employed care must be taken not to burn the vulcanite, which will leave its surface rough and irritating. All of the foregoing pessaries are made in the form of an elongated horseshoe. The curved upper end adapts itself to the posterior fornix, while the curved lower end adapts itself to the lower portion of the vagina. With its upper sacral curve and lower pubic one it therefore corresponds to the vaginal slit, and when within the vagina the concavity of the upper sacral curve looks forward, while the concavity of the lower pubic one looks backward. If properly fitted the vaginal walls grasp it closely both anteriorly and posteriorly. Since, however, the 560 A TEXT-BOOK OF GYNECOLOGY. posterior vaginal wall is narrower below than it is above, Albert Smith's instrument is the more scientific. Thomas's modifica- tion is especially adapted to those cases where the sacral curve is very pronounced and the vagina long. In fitting a pessary a digital examination should first be made for the purpose of obtaining the dimensions of the vagina. A pessary is then selected which will fulfil as nearly as possible the requirements of the case. Should the sacral curve be very pronounced the instrument should be molded accordingly. Should the vagina be comparatively straight it may be necessary to lessen this curve. The instrument should be shorter and nar- rower than the posterior vaginal wall, so that no tension will be produced when it is in position. The lower bar is then grasped with the index finger and thumb of the right hand, the labia separated with the fingers of the left, and the upper sacral curve turned so that the pessary at its widest part will correspond to the antero-posterior diameter of the vaginal outlet. It is kept well pushed back toward the perineum, so as not to pinch the tissues anteriorly between the pessary and the pubic bones. After it has passed the ostium vaginæ the index finger is carried under the lower bar and above the upper in such a way as to convey the latter back of the cervix. Unless this precaution be taken the upper bar will, in all probability, pass into the anterior fornix instead of the posterior. When in place the lower end should be just within the vaginal orifice. It is compressed be- tween the posterior face of the pubic segment and the oblique anterior face of the sacral segment. In this position the intra- abdominal pressure acts nearly equally upon both the superior and inferior bars, and the cervix is drawn backward with a cor- responding elevation of the fundus. An examination should be made in the erect posture before the patient leaves the consulting If the pessary is too small it will show a disposition to turn transversely; if it is too wide the patient will complain of more or less tension and distress. The lower end should not project below the pubic bones. It may be necessary to introduce several instruments before a proper one is obtained. Experience will, however, enable the physician in most cases to select one of proper size and shape after one or two trials. room. Before leaving the office the patient should be instructed to RETROVERSION AND RETROFLEXION. 561 return at once if the instrument causes pain. She should report herself for examination in the course of three or four days to see whether or not it keeps its proper position. After it becomes evident that the pessary is perfectly fitted she may wear it for an indefinite length of time without removing it. It is necessary to resort to occasional cleansing injections whenever a pessary is within the vagina. So far as any distress is concerned, the patient should be entirely unconscious of its presence, nor should it interfere with coition. Cases are every now and then met with where, because of the great weight of the uterus, or because of injury done to the pel- vic floor and perineum, the ordinary intravaginal pessary will not accomplish the desired end. It may then be necessary to utilize an instrument suspended from the waist. For this purpose FIG. III. FIG. 112. G.TIEMANN & CO. G.TIEMANN&CO. THOMAS'S CUTTER'S RETROVERSION THOMAS'S CUTTER'S ANTEVERSION PESSARY. PESSARY. Thomas's modification of Cutter's anteversion and retroversion pessaries are the ones most generally used (Figs. 111 and 112). All forms of extra-vaginal stem pessaries are objectionable, and should be resorted to only when intravaginal support is insufficient. When the abdomen is unduly pendulous and large much relief may be afforded by a properly fitting abdominal supporter. It sustains the abdominal walls, lifts them upward, and changes the direction of the intra-abdominal pressure. Those in most common use are Hood's and the London Abdominal Sup- porter. In spite of the utmost skill in fitting pessaries cases will every now and then be met with where any form of instrument will fail to bring the desired relief. This may be due to relaxation 36 562 A TEXT-BOOK OF GYNECOLOGY. of the perineum and pelvic floor, to laxity of the vagina, to ovarian displacements, or to periuterine inflammation. If it is probable that a cure can be accomplished by restoring the perin- eum and pelvic floor to their normal condition, this should be done. Indeed, before the more serious operations from above, having for their object the correction of the displacement, are resorted to reparation of the pelvic floor and perineum should always be made. Failing to afford relief by these measures, and failure will be the rule where the ovary is prolapsed with the uterus, there are two operations, one or the other of which may be utilized. The first is known as the Alexander Operation. It was revived by Alexander of Liverpool, although the idea of correcting retro- displacements of the uterus by shortening the round ligaments belongs, it is claimed, to Alquie of Montpellier. This operation is especially applicable to backward and downward displace- ments. After its revival by Alexander it enjoyed a certain degree of popularity, but it has again fallen into disrepute. There is, in the first place, great uncertainty in finding the round liga- ments; and, unfortunately, the results are not permanent, the displacement, in at least a goodly number of cases, becoming as bad as ever after a certain length of time. I have performed the operation in all ten times. Four of these cases were absolute failures, because of my inability to find the ligaments, or because of their deficient size when found. In one case but one ligament was found. The five remaining cases were entirely successful. However, the number of failures has led me, as it has led the majority of specialists in this country, to discard the operation for that of ventral hysterorrhaphy, or fixation of the uterus to the anterior abdominal wall. I have in the dead-room examined the round ligaments of a large number of subjects, and have studied the technique of the operation under the personal demonstration of a number of its warmest advocates. There is absolutely no way of determining the size of the ligaments before the inguinal canal is opened. If they are very small the most profound anatomist will fail to find them. I shall, therefore, not take the trouble to describe the technique of the operation. I shall like- wise refrain from describing vaginal hysterorrhaphy, or fixation RETROVERSION AND RETROFLEXION. 563 of the uterus through the vagina, because of the dangers attending this method. Gastro-hysterorrhaphy, or Ventral Fixation of the Uterus. -This operation was first suggested by the fixation of the pedicle of ovarian cysts outside the abdomen when this practice was common. It was observed that this procedure corrected the displacements of the uterus; hence the idea of fastening the uterus to the abdominal wall for the sole purpose of overcoming the displacements. It is claimed that gastrohysterorrhaphy was performed for the first time in 1869 by Koeberle. To Olshausen, however, is due the credit of systematizing it. In this country Howard A. Kelley, Polk, Wylie, Mundé, and others have been foremost in popularizing it. Its value is now fully established. Operative Technique.—The technique of the operation, simple as it is, has been made difficult to comprehend by the operative details insisted upon by most of the authors. I shall, therefore, endeavor to give as simple a description of it as is possible. The abdomen is opened in the median line as for oöphorec- tomy. After separating any adhesions that may exist, the fundus is pushed forward. The appendages are ablated or not, accord- ing to the indications; if diseased, they are, of course, removed. It is safer, I think, in ovarian prolapse to remove the displaced ovary. A curved needle armed with silver wire is then carried through the abdominal wall of the left side one half inch from its border. It next penetrates the uterus opposite the insertion of the two round ligaments as shown in Fig. 113. The needle is carried under the peritoneum and through the superficial layer of muscular tissue to the extent of a quarter of an inch, when it penetrates the abdominal wall of the opposite side from behind forward and is brought out on the skin surface. A second suture is introduced above this and, if necessary, a third. Usually, two are sufficient. After the introduction of the sutures, the anterior uterine sur- face over the area occupied by the sutures, and the opposite peri- toneal surface of the abdominal wall, are irritated with the point of a scalpel in order to promote adhesions. Great care should be observed that no loop of intestine finds its way between the 564 A TEXT-BOOK OF GYNECOLOGY. uterus and the abdominal wall. In order to guard against this the wire sutures should be kept taut by an assistant while the abdomen is being closed; this is done in the usual way with silk sutures. Sufficient tension upon the wire sutures is necessary to keep the uterus in close contact with the abdominal wall. In order to lessen the irritation of the skin surface it is my practice to place strips of iodoform gauze beneath the wire sutures before they are twisted. Finally, a retroversion pessary is introduced into the vagina; this should be worn for some weeks for the purpose of sustaining the uterus until the utero-abdominal adhe- sions become firm. The patient is kept in bed for some time FIG. 113. GASTRO-HYSTERORRHAPHY. (Leopold.) longer than is ordinarily necessary after abdominal section, so that the newly-formed adhesions may not be prematurely stretched. Drainage is unnecessary except in cases where extensive adhesions have been separated. Results and Prognosis of Gastro-hysterorrhaphy. It cannot be said that this operation is as free from danger as is the Alexander. Under modern antiseptic methods, however, the mortality is very low. Nevertheless, the operation should be reserved for those cases of retro-displacement which cannot be overcome in the ordinary way, as, for instance, when the fundus is bound down by adhesions or the ovary prolapsed. It is true RETROVERSION AND RETROFLEXION. 565 that occasionally the cure is not permanent, but I am inclined to believe that this is due to faulty operative technique. Experi- ence thus far has proved that the operation does not interfere with pregnancy, but it is yet too recent to speak dogmatically regarding this point. When done for adhesions or for ovarian prolapse, it is probable that much good would be accomplished even were nothing more done than to overcome the adhesions or remove the offending ovary. Whenever abdominal section is made for other purposes, and the uterus is found retrodisplaced, it should be fixed to the anterior abdominal wall before the abdomen is closed. Strangely enough micturition is not interfered with. Wylie of New York shortens the round ligaments within the abdomen for the purpose of overcoming retrodisplacements. He folds these structures upon themselves and at their middle portion, some distance from the uterus, sutures them, first scraping the peritoneum between the folded surfaces. Bode of Dresden transfixes the round ligaments near the internal abdominal ring with a needle threaded with aseptic silk. He then passes the needle through the corresponding uterine cornua at the insertion of the ligaments. After the two ligatures are tied the ligaments are shortened to an extent corresponding to the distance between the two knots. Polk brings the round ligaments together in the form of an X above the bladder, securing them in this position with sutures. All of these operations overcome the displacements by shortening the round ligaments, as does the Alexander. My unsatisfactory experience with the Alexander, and the peculiar tendency of the round ligaments to stretch, has led me to practise gastro- hysterorrhaphy in preference. Kaltenbach, Howard A. Kelley, Roux, and others have practised to a greater or less extent abdominal hysterorrhaphy without laparotomy. This seems to me infinitely more danger- ous than laparotomy for the same purpose. By it there is great danger of injuring the intestines, as an example furnished by Roux emphatically demonstrates. This operator, feeling some misgivings at the moment of passing the needle, opened the abdomen and found that a loop of intestine would have been penetrated had he persisted. 566 A TEXT-BOOK OF GYNECOLOGY. Gastro-hysterorrhaphy: Illustrative Cases. CASE LXIX.-Retroversion of the Uterus with Procidentia of the Second Degree. Perineorrhaphy and Gastro-hysterorrhaphy. Recovery.—Patient, æt. 36. Referred to me by Dr. L. T. Van Horn of Rives Junction, Michigan. Married for fourteen years. Has had two children. Uterine trouble dates back to the birth of first child. She had an operation some years ago upon the cervix and perineum, but the newly made perineum is of a most superficial character and is absolutely useless, although its antero-posterior diameter measures at least two inches. There is constant soreness in the back with a great deal of pain in the left ovarian region. She describes this pain as being of a pressing sensation, as though there were a ball pressing against the pelvis. The menses are quite regular, but exceedingly painful. She also suffers greatly from headache. Physical Examination.—The os rests upon the perineum, the uterus is retroflexed, and the left ovary is beneath the fundus. The patient was placed upon the operating table November 11, 1892. The peri- neum was first repaired by the author's method and a large retroversion Hodge pessary placed in the vagina. The abdomen was then opened, the appendages removed, and the fundus stitched with two wire sutures to the anterior abdominal wall. No drainage was introduced. The abdominal walls were at least four inches thick and some difficulty was experienced in passing the sutures. The patient con- valesced nicely and returned to her home on December 24th. She is now (six months after the operation) quite well. CASE LXX.—Obstinate Retroflexion of the Uterus with Cystic Degeneration and Prolapse of the Right Ovary. Gastro-hysterorrhaphy and Salpingo-oöphorectomy. Recovery.-Patient, æt. 24. Referred to me by Dr. Walker of Salem, Michigan. She has been almost entirely incapacited for the last three years because of a constant distress and bearing-down sensation in the pelvic region, which completely unnerves her. I found upon digital examination retroflexion of the uterus, with prolapse of the right ovary, which was evidently greatly enlarged. The patient was placed under palliative treatment for three months, but in spite of every effort I could not keep the ovary out of the cul-de-sac, where it was constantly squeezed and irritated. She very willingly consented, as a final resort, to abdominal section. On February 1, 1892, the abdomen was opened and the right ovary, which was four or five times its normal size, removed. The fundus was stitched to the anterior abdominal wall in the usual way. The left ovary was not enlarged, though it was attached to the floor of the pelvis by adhesions. These were broken up and the appendages of the left side left intact. This was done at the urgent request of the patient, who was about to be married and desired very much to have children. The abdomen was closed without drainage. The temperature reached 101° on the morning of the second day, and there was evidently a slight localized peritonitis; but under a saline cathartic and bryonia this quickly subsided, and the convalescence was rapid and complete. She has returned to her business, and is now doing with perfect ease the work of a milliner. CASE LXXI.—Intractable Dysmenorrhea following Ovariotomy for the Removal of a Large Ovarian Cyst. Retroflexion. Oöphorectomy and Gastro-hysterorrhaphy. Recovery.-Patient, æt. 38. Referred to me by Dr. S. S. Moffatt of Washington, D. C. RETROVERSION AND RETROFLEXION. 567 Married; sterile. Has been a victim of dysmenorrhea from girlhood. Four years previously to consulting me she underwent an operation for the removal of a large ovarian cyst. She did not convalesce well, and there was left behind a distressing her- nia of the abdominal wound. The dysmenorrhea became more marked after the removal of the cyst. Dr. Moffatt had exhausted all ordinary measures to overcome the dysmenorrhea. I therefore reopened the abdomen in January, 1891, removed the appendages of the opposite side, and stitched the uterus to the anterior abdominal wall. The scar- tissue of the old wound was entirely removed and, owing to the thickness of the abdominal walls, wire tension sutures were introduced. The wound was then closed with silk sutures. The patient was exceedingly nervous and her mental condition closely bordered on insanity. She made a somewhat tedious convalescence, but finally recovered. There have been no signs of menstruation since the operation and the uterus remains permanently fixed in front. CHAPTER XXXVII. DISPLACEMENTS OF THE UTERUS.-(Continued.) Lateral displacements of the uterus are frequently associated with the forms studied in the preceding chapter, and, when slight, are of no consequence. As has been shown a slight lateral version, because of the position of the rectum, is physio- logical. Pathologically it results, in nearly all instances, from FIG. 114. C. 60ULLNAZ UTERO-VAGINAL PROLAPSE. inflammation of one or the other broad ligament, or from tumors within the pelvis. The treatment, therefore, should be directed to the condition giving rise to the displacement. PROLAPSE OF THE UTERUS. It is customary to speak of three degrees of prolapse or descent of the uterus. In the first degree the organ is somewhat lower in the pelvis than normal, though its axis corresponds to the plane of the inlet. 568 PROLAPSE OF THE UTERUS. 569 In the second degree the cervix reaches the ostium vaginæ and the axis of the uterus corresponds to the pelvic mid-plane. In the third degree the uterus is wholly or in part outside of the vagina, and its axis corresponds to that of the pelvic outlet. This is known as complete procidentia (Fig. 116). FIG. 115. e COMPLETE PROLAPSE OF THE BLADDER, UTERUS, AND RECTUM. (a) Left labium; (b) edge of left vaginal wall, which has been cut away to expose (c) uterus, and (d) bladder; (e) anus, through which the rectum (f) protrudes for over two inches. The ovaries and broad ligaments are stretched and brought down to the level of the external labia, but are healthy in structure. The greater part of the bladder has been carried downward beyond the labia together with the inverted anterior wall of the vagina. The patient had been thus diseased for many years. (Museum R. C. S. Photographed by the Author.) Etiology.-Anything that tends to weaken or destroy any of the natural uterine supports will predispose to prolapsus uteri. Of the various causes, parturition is unquestionably the most important. The imperfect involution of the organ leaves it heavy and congested. The uterine ligaments likewise undergo 570 A TEXT-BOOK OF GYNECOLOGY. imperfect involution and are, consequently, easily stretched. Added to these there is frequent relaxation and injury to the pelvic floor which weakens the support from below. If, in this condition, muscular exercise is excessive, the organ is crowded more and more toward the pelvic outlet until finally it makes its appearance externally. The rectum and bladder may be pro- lapsed with the uterus (Fig. 115). FIG. 116. e COMPLETE PROCIDENTIA OF THE UTERUS, VAGINA, AND BLADDER. (Wood.) (P) pubes; (c) cervix; (e) enterocele. The cul-de-sac of Douglas is filled with intestine. From a patient aged 67. The usual form of complete procidentia is shown in Fig. 116, the case from which the illustration was taken coming under my own observation. General feebleness of tissue and senility also tend to produce procidentia. The displacement is much more common in elderly women. It is often secondary to vaginal prolapse. PROLAPSE OF THE UTERUS. 571 Pathology. Structural changes are usually associated with the prolapsed organ. The cervical mucous membrane is everted and erosions from friction are of frequent occurrence. Endometritis with metritis and hypertrophy exist in nearly all instances. The vagina becomes markedly hypertrophied in complete procidentia and its cavity may be entirely lost by the eversion. Its rugæ are destroyed, and from long exposure to friction its epithelial layer becomes so thickened as to resemble true skin. There is, even in descensus of the first and second degrees, more or less prolapse of the anterior and posterior vagi- nal walls with resulting cystocele and rectocele. The uterine appendages are necessarily carried downward with the uterus and, not infrequently, are inflamed. Symptoms. These will depend upon the degree of the pro- lapse and upon the complicating factors. The most frequent sub- jective symptom is a bearing-down sensation. If the uterus pre- sents externally the patient will herself suspect the cause of the trouble. Difficult or painful micturition is an early and often a prominent symptom, though, strangely enough, in some cases of complete procidentia micturition is not especially difficult. There is likewise more or less rectal irritation. The descent is increased upon assuming the erect posture, and if the procidentia is of the first or of the second degree it is relieved by lying down. Men- strual disturbances are not necessarily very great. Locomotion is interfered with and the general distress is aggravated by mus- cular exertion, especially lifting. Should the displacement occur suddenly, as a result of severe muscular exertion or a fall, which is rarely the case, the symptoms of shock and pressure may be most marked. The physical signs are pronounced. Upon vaginal examina- tion the uterus will be found either low down in the vagina or com- pletely protruding from it. The degree of prolapse can best be determined by completing the examination in the erect posture. The uterus is usually increased in length. Prolapsus uteri will have to be differentiated from- Inversion and polypus; Rectocele; Cystocele ; Hypertrophic elongation of the cervix. 572 A TEXT-BOOK OF GYNECOLOGY. Inversion and Polypus.-In inversion of the uterus the os can- not be found, and the bimanual will show the absence of the fundus above. In polypi the uterus will be found above and unless adhesions exist can be penetrated with the sound.* Rectocele.-As we have seen, this is nearly always associated with uterine prolapse. A degree of rectocele sufficiently marked to simulate complete procidentia is of exceedingly rare occur- rence. The uterus will be found above the rectocele. The tumor can be penetrated per rectum, either with the finger or the sound. Cystocele.-A sound introduced into the bladder will penetrate the tumor. The uterus is found above. Hypertrophic Elongation of the Cervix.-The uterine cavity is greatly increased in length and the bimanual will show the fundus in its normal position. Prolapsus may be associated with this condition (Fig. 117). Prognosis. This will depend upon the degree of prolapse, the age of the patient, and the existing complications. Usually the condition becomes more and more aggravated as time goes on unless operative interference is resorted to. Prolapse of the first or of the second degree may be overcome by properly fitted pessaries. When, however, procidentia becomes complete a cure is rarely accomplished by palliative measures, although the patient may be made more comfortable by them. In nearly all cases, except when the patient is very old and complete proci- dentia has existed for a long time, a cure is possible by proper surgical interference. Treatment.-An effort should first be made to remove the cause or causes of the displacement. The treatment, therefore, should be directed to chronic metritis or endometritis, if these affections exist; or to the reparation of existing tears of the cer- vix or injuries to the pelvic floor. All clothing should be suspended from the shoulders in order to reduce intra-abdominal * I once removed a soft myomatous tumor springing from the cervix which pro- jected into the vagina and which was as large as a fetal head (Medical Counselor, Vol. xi, p. 116). Adhesions had obliterated the cervical canal and at the most convex portion of the tumor there was an opening corresponding very closely to the external os. After breaking down the adhesions under ether, the sound passed into the uterine cavity for nearly five inches, so that the diagnosis was made certain. The confusion, however, was very great. PROLAPSE OF THE UTERUS. 573 If the abdomen is pendulous the pressure to its minimum. patient should wear an abdominal supporter. The bowels and bladder should likewise receive attention. Excessive muscular exertion is, of course, injurious. The genu-pectoral posture will afford much relief, bringing rest to the uterine supports. When the uterus can be gotten into the vagina, astringents, such as the saturated solution of alum, or powdered tannin sprinkled upon glycerin tampons, will do much good. FIG. 117. HYPERTROPHIC ELONGATION OF THE CERVIX WITH PROLAPSE. A median vertical section of the pelvic organs of an adult female. The cervix uteri is much hypertrophied and elongated. The vagina is prolapsed, being com- pletely everted. In descending with the vagina the uterus has drawn down its peritoneal investments. The walls of the bladder are thickened. (Museum R. C. S. Photographed by the Author.) Some difficulty may be experienced in replacing the uterus in complete procidentia. Before attempting to do so the rectum and bladder should be emptied. If necessary the patient can be placed in the genu-pectoral posture, when pressure upon the cervix is made and the prolapsed uterus pushed upward. Too 574 A TEXT-BOOK OF GYNECOLOGY. much force should not be exerted, especially in elderly women, as there is danger of producing sloughing. In many in- stances the reduction requires fifteen or twenty minutes for its completion. After the uterus is reduced an attempt should be made to sustain it in its normal position by a pessary. Slight cases of procidentia are frequently associated with more or less retrodis- placement and may be corrected by a Hodge pessary, or one of FIG. 118. FIG. 119. GTIEMANN' CO. INFLATED SOFT RUBBER PESSARY. G. TIEMANN & CO. INFLATED BALL PESSARY. FIG. 120. GTIEMANN THOMAS'S CUTTER'S CUP PESSARY FOR PROLAPSE. its modifications. If the rectocele and cystocele are at all marked, Greenhalgh's pessary with transverse bars is preferable to the ordinary form. When this instrument cannot be retained relief may be afforded by an inflated soft rubber pessary (Figs. 118 and 119). These act by distending the vagina; hence as time goes on a larger instrument will be required. Any pessary which sustains the parts by simply distending the vagina is objectionable. Nevertheless, every now and then cases will be PROLAPSE OF THE UTERUS. 575 met with where operative interference is impracticable, when much relief will be experienced from the use of instruments of this kind. When the sustaining power of the pelvic floor is en- tirely destroyed some form of vaginal stem pessary is ordinarily preferable to elastic or air pessaries. Of these Thomas's modifica- tion of Cutter's cup pessary (Fig. 120) is one of the best. The Mackintosh uterine supporters have also been much used for this purpose. Any form of vaginal stem pessary should be removed at night while the patient is in the recumbent posture, and she should be instructed how to reintroduce the instrument upon arising. In all instances where the patient cannot tolerate a pessary much relief will be experienced by sustaining the parts by properly applied tampons medicated with some astringent solu- tion or with powdered tannin. Operative Interference.-The various operations for uterine prolapse have for their object the restoration of the pelvic floor and perineum and the narrowing of the vagina by anterior and posterior colporrhaphy. After these operations are done it may be necessary to fix the uterus from above to the anterior abdom- inal wall. These various operations are described in Chapter LII. Episeiorrhaphy, or closing the vulvar outlet, is now rarely resorted to for procidentia. In most instances where entire reliance is placed upon it for the purpose of keeping the uterus within the vagina, prolapse again takes place. Hysterectomy, except in cases where the uterus cannot be returned to the vagina, is hardly a justifiable procedure. The operation does not overcome the enterocele, and after the uterus is removed intra-abdominal pressure will force the intestines and vagina from the ostium. In most cases where reposition of the uterus is impossible the patient is so far advanced in years, and the prolapse has existed for so long a time, as to make hysterectomy unadvisable. The comfort of the patient is not greatly augmented by the operation. Gastro-hysterorrhaphy, supplemented if necessary by an opera- tion on the perineum, vagina, and cervix, may be done as a final resort. It is especially indicated if the prolapse is compli- cated with abdominal tumors which in themselves justify 576 A TEXT-BOOK OF GYNECOLOGY. laparotomy. Le Fort has devised an ingenious operation for keeping the uterus within the vagina. It consists in removing a vertical strip of mucous membrane of varying width from opposite vaginal walls and stitching the vivified surfaces together. INVERSION OF THE UTERUS. The term "inversion" is applied to invagination of the uterus on itself in such a way that the organ is turned inside out. The accident may occur suddenly, as after parturition, or it may be produced gradually, the result of some intra-uterine growth. A very large per cent. of the cases reported are directly traceable to labor and the puerperal state. FIG. 121. THE SEVERAL DEGREES OF IN- TRA-UTERINE INVERSION RE- PRESENTED SCHEMATICALLY. U, uterus; V, vagina. (Auvard and Devy.) Fig. 121 shows, schematically, the several stages of intra-uterine inver- sion, which may remain partial or be- come complete. If complete, the in- verted fundus projects into the vagina, and often externally. The organ may become hard or remain soft and vascu- lar. If the cervical canal constricts the parts, congestion is usually marked and the constriction may give rise to gangrene and sloughing. The Fallo- pian tubes are drawn within the in- verted cup and are more or less con- stricted by the upper peritoneal ring. Adhesions rarely form between the opposing peritoneal surfaces. If the uterus is not prolapsed the position of the bladder remains un- altered in its position; should there be prolapse, a cystocele is formed. Etiology.-Inversion of the uterus may occur in any one of the following ways:- 1. The fundus is drawn down by improper traction upon the cord during parturition. INVERSION OF THE UTERUS. 577 2. Prolapse of some part of the fundus is caused by degener- ation of the walls of the uterus. This is made worse by uterine contractions and by pressure from above. The form of degen- eration varies. Scanzoni believes it to be in most instances fatty. According to A. R. Simpson, sarcomatous degeneration is the most frequent form responsible for the accident. FIG. 122. AN UNIMPREGNATED INVERTED UTERUS WITH THE VAGINA, OVARIES, AND OTHER PARTS. Bristles are placed in the uterine orifices of the Fallopian tubes, which by the inver- sion of the uterus have come to open obliquely into the upper part of the vagina. Below is a polypus which was attached to the fundus of the uterus at the rough spot now seen on the side of the Fallopian tube. A ligature was applied near this attachment and it sloughed off just before the patient died. (Museum R. C. S. Photographed by the Author.) 3. A polypoidal tumor, either malignant or non-malignant, excites uterine contraction. The contractions force the tumor downward, which drags a portion of the fundus with it. The 37 578 A TEXT-BOOK OF GYNECOLOGY. inversion may remain partial, the fundus not escaping from the os externum; or it may completely dilate the cervical canal and pass into the vagina (Fig. 122). 4. Inversion from below upward may take place. Here there is first eversion of the cervix, when the lower part of the uterine body first passes into the cervical canal. This is the passive in- version of Matthews Duncan, and is produced by uterine inertia and not by uterine contractions. It will thus be seen that the factors tending to produce inver- FIG. 123. INVERSION OF THE THIRD DEGREE. (Auvard and Devy.) sion are those which alter the consistence and structure of the uterine tissues. During parturition the organ is, of course, greatly enlarged and the cervix dilated, so that it is a very easy matter to drag the fundus downward by improper management of the third stage of labor. General debility and wasting diseases also act as predisposing causes. Severe muscular exercise and pres- sure from above may force the fundus into the uterine cavity. Symptoms. If the inversion occurs suddenly during partu- rition the patient will complain of a feeling as though something INVERSION OF THE UTERUS. 579 had given way, followed by a bearing-down sensation in the pelvis. The hemorrhage is usually severe. The large mass within the vagina interferes with micturition. Shock and even fatal collapse may result from the accident. If the condition is not corrected and the patient's life is spared, the symptoms of chronic inversion present themselves. These are variable. Usually hemorrhage either in the form of menorrhagia or met- rorrhagia is the most prominent symptom; associated with the hemorrhage are pelvic pain and distress, difficult micturition and defecation, backache, painful locomotion, and the constitutional symptoms due to the unnatural loss of blood. Leucorrhea is also a prominent symptom. Physical Signs.—When acute the large vascular fundus will be found in the vagina, while the hand externally will fail to locate, in its usual place, the hard contracted uterus. In its stead there will be found a truncated body low down in the pelvis. In chronic cases there will be detected upon digital examina- tion a polypoidal body within the vagina which can be traced to the cervix. If the inversion is not complete, the fundus not having escaped into the vagina, intra-uterine exploration will locate it within the uterus. In the event of complete eversion, the con- tinuity of the tumor with the inner surface of the cervix will be noted. The uterine canal is much shortened and the sound will not penetrate it for more than an inch or an inch and a half. Occasionally adhesions form between the cervical canal and the fundus, so that the latter cannot be penetrated by the sound. The bimanual is next practised. The fundus is not found in its normal position and, if the abdominal walls are not too thick, the characteristic depression can be detected. If the conditions are unfavorable for successful bimanual the absence of the fun- dus in its normal position may be determined by drawing the tumor within the vagina downward and examining per rectum. A sound now passed into the bladder will come in contact with the finger in the rectum, showing the absence of the uterus be- tween the two. By careful examination of the tumor it is usually possible to locate the opening of the Fallopian tubes. 580 A TEXT-BOOK OF GYNECOLOGY. The condition will have to be differentiated from prolapsus uteri and from hypertrophic elongation of the cervix (v. p 571). Termination.-A spontaneous cure of the inversion is of rare occurrence. Unless corrected the hemorrhage and dis- charge, together with the friction resulting from the unnatural location of the fundus within the vagina or externally, greatly prostrate the patient. There is constant danger of strangulation with consequent septicemia. Treatment.—An effort should be made to reinvert the uterus as soon as the accident is discovered. Immediately after de- livery this is not usually difficult. The placenta should be com- pletely detached and the fundus boldly pushed upward with one hand, while pressure is exerted from above with the other. The hand should remain in the uterine cavity until the uterus con- tracts firmly down upon it. In cases of long standing the treatment is much more difficult, although Audige records a case of thirty years' duration in which a cure was accomplished. An effort may be made to restore the fundus to its normal position by- Manual reduction; Reduction by gradual compression; Taxis with instruments. Too much persistence should not be practised. Failing with these measures, especially in chronic cases, we are then justified in resorting either to amputation or to vaginal hysterectomy. Manual Reduction.-After anesthesia the fundus is grasped with three fingers of one hand, while the other hand steadies the uterus through the abdominal wall. An attempt may be made either to reinvert the fundus en masse, or to reduce it gradually by inverting first one cornu and then the other. Courty makes, if necessary, several longitudinal incisions through the circular fibers of the cervix in order to overcome the contraction. He then exerts counter pressure upon the truncated end of the uterus with two fingers in the rectum, while the attempt is being made to reinvert the fundus. After the fundus is pushed into the uterine cavity Emmet advises closure of the cervix with sutures if the reduction is not complete. INVERSION OF THE UTERUS. 581 Reduction by Gradual Compression.—The patient is prepared by hot vaginal douches and rest in bed, in order to reduce con- gestion as much as possible. This preparation is also important before manual reduction is attempted. Gradual pressure may be exerted by an air pessary (Fig. 118), by a cup stem pessary fixed on an abdominal belt, by a colpeurynter, or by tamponne- ment with iodoform gauze. Pozzi prefers the latter method. He packs with some force long strips of gauze around and above the tumor. These are removed every two or three days. The Fig.2. FIG. 124. Fig.1. b g G.TIEMANN & CO C WHITE'S UTERINE REPOSITOR. patient is kept in a horizontal position during the treatment. Evacuation of the bowels and bladder should be carefully looked after. Pozzi maintains that this treatment will accomplish all that can be done by other methods of gradual compression, and that it possesses the advantages of being simple and requiring no special instrument. Taxis with Instruments.—Special repositors have been de- vised for the purpose of exerting taxis. Fig. 124 represents White's repositor. It consists of a staff with a soft rubber cup attached to one extremity, which fits over the fundus, and a spiral 582 A TEXT-BOOK OF GYNECOLOGY. spring attached to the other, which is applied against the chest of the operator. This instrument is useful, but long-continued pressure by it is liable to produce sloughing. Thomas's method of opening the abdomen and dilating the cervical ring with an instrument similar to a glove-stretcher is no longer recommended. J. M. Baldy* of Philadelphia says that he has seen the abdomen opened, the cervix dilated with dilators, and traction exerted from above with a stout cord passed through the fundus into the vagina without avail. He, therefore, considers all of these methods distinctly illogical and dangerous, and believes they should be set aside in favor of the safer method of vaginal hysterectomy after a reasonable attempt has been made to over- come the inversion with the vaginal tampon. Of the radical operations, the inverted fundus may be ampu- tated, or the entire uterus removed by vaginal hysterectomy. The choice between amputation and hysterectomy will depend upon circumstances. As a general rule I think vaginal hysterec- tomy, as now practised, is the preferable operation. If the fundus is in the way, the cervix can first be secured in an elastic ligature, by which means hemorrhage is controlled, and the tissue below cut away. This step will enable the operator to remove the cervix and secure the broad ligaments with but little difficulty. If simple amputation be resorted to, care must be observed not to permit the stump to retract into the abdominal cavity. An elastic ligature is thrown about the neck of the tumor, below which two or three wire sutures are made to transfix the cervix antero-posteriorly. The uterus is then removed half an inch below the sutures and the bleeding points of the stump secured with catgut. The edges of the wound are next approximated with the wire sutures previously passed. These are left long enough to project from the vagina, so as to prevent retraction of the stump. Superficial sutures may be placed between the deeper ones if necessary to insure perfect coaptation of the mucous membrane covering the stump. The elastic ligature is removed after the wire sutures are secured. This method is preferable to amputation or by the écraseur. * Medical and Surgical Reporter, July 25, 1891. CHAPTER XXXVIII. FIBROID TUMORS OF THE uterus. Definition.-Fibroid tumors of the uterus result from localized hypertrophy due to increased nutritive activity of the uterine muscular and connective tissue. They are composed of both con- nective tissue and muscular elements, and are, therefore, both fibromatous and myomatous in character. The fibrous and muscular tissue rarely exist in equal proportions, the one or the other preponderating. In by far the larger number of cases the fibrous tissue is in excess, and the term uterine fibroid, most commonly applied to these new formations, is, therefore, not inappropriate. Pathology. When first formed, they consist largely of muscular fibers of the non-striped variety, and are simply outgrowths from preëxisting muscle tissue. Embedded in the stroma of non-striped muscle tissue are glands lined with ciliated columnar epithelium similar to that found in the uterine glands. As time goes on these growths usually undergo fibrous trans- formation, the fibrous tissue developing at the expense of the muscular, although rarely, if ever, supplanting it entirely. When the muscular tissue preponderates they are usually very vascular and contain large sinuses. After undergoing fibrous changes, the vessels are surrounded by a mass of fibrous tissue, which has a tendency to obliterate them (Gibbes). Varieties. In the beginning all fibroid tumors are located in the walls of the uterus, and are, therefore, interstitial or intra- mural (Fig. 125). As time goes on they grow either toward the peritoneal cavity, becoming subserous, or toward the uterine cavity, becoming submucous. Hence, clinically, three varieties are distinguished-interstitial, subserous, and submucous. The tumor may remain indefinitely in the walls of the uterus, assum- ing large dimensions. Should it approach either the serous covering of the uterus or its mucous lining, the surrounding 583 584 A TEXT-BOOK OF GYNECOLOGY. parenchyma will be excited by its presence and the resulting contractions will force it still farther toward the abdominal or the uterine cavity. As time goes on the broad base is often converted into a slender pedicle, producing the so-called pedun- culated subserous, or the pedunculated submucous fibroid, FIG. 125. B لة Peritoine B 4 Péritoine A Muqueuse Muqueuse C' DIAGRAM SHOWING THE BEGINNING OF FIBROMA UTERI AND THEIR MODE OF GROWTH. (Auvard and Devy.) A. Interstitial fibroid, which remains interstitial (1, 2, 3, 4). B. Fibroid, which was at the beginning interstitial, but which has developed in the direction of the perito- neum, becoming gradually transformed into a pedunculated sub-peritoneal tumor, B', C. Fibroid, which was at the beginning interstitial, but which has developed in the direction of the uterine cavity, becoming gradually transformed into a sub- mucous polypus, C'. as the case may be. The last-named condition constitutes a fibrous polypus. Number, Size, and Location.-The number of uterine fibroids varies greatly-from one to fifty. Thomas records a case where the uterus, removed from a negress, contained thirty-five tumors, FIBROID TUMORS OF THE UTERUS. 585 varying in size from that of a marble to a fetal head. They are oftener located in the body of the uterus, but may develop in any part of the organ. The posterior wall of the fundus is the most frequent location; the rarest of all is the cervix. In FIG. 126. 4637 The tumor (Museum R. C. S. A uterus in the walls of which are eight or nine large fibrous tumors. cut open is imbedded in the posterior wall of the womb. Photographed by the Author.) size they range from that of a walnut to tumors weighing seventy- five pounds. Structure. As already intimated, the proportion of the mus- 586 A TEXT-BOOK OF GYNECOLOGY. cular and fibrous tissue varies greatly. When the former pre- ponderates, the tumor is soft, vascular, and grows rapidly. The muscular fibers blend insensibly with those of the uterus. Upon section, the tumor is of a pale flesh color. If the fibrous element is in excess, the consistence is firm and cuts like cartilage. Fibroid tumors are enclosed in a layer of loose fibrous tissue surrounded by a muscular layer; this is the so-called capsule. FIG. 127. 4639 A uterus, enlarged by pregnancy, attached to the right side of which is a perfectly solid fibro-myomatous tumor, ten inches in its vertical diameter. It is attached to the uterus by a thin band of connective tissue four inches in length. (Museum R. C. S. Photographed by the Author.) But few blood-vessels penetrate their substance, although the capsule and contiguous structures often contain large venous sinuses, which supply nutrition to the growth by transudation. Occasionally, as has been shown, they possess a cavernous struc- ture of dilated blood-vessels (Hart and Barbour.) Microscopically they consist of non-striped muscular fibers embedded in a fibrous stroma. The fibrous tissue The fibrous tissue may be sepa- FIBROID TUMORS OF THE UTERUS. 587 rated by lymphatic tissue (Klebs). Lorey has traced nerve fibers into the substance of fibroid tumors, although the sub- stance itself is not sensitive. Sub-mucous fibroids are sensitive while the capsule is yet intact, because of the nerve supply of the mucous membrane (Freund). Mode of Growth.—Subperitoneal tumors grow toward the peri- toneal cavity. They may be either pedunculated or sessile, the size of the pedicle varying greatly in different cases. As they extend toward the peritoneal cavity they drag the uterus with them, and often greatly distort this organ. The traction induced in this way has been known to separate the body of the uterus from the cervix (Virchow). Should a tumor not find its way into the peritoneal cavity but remain in the pelvis, incar- ceration may occur. Occasionally the pedicle becomes twisted, as in ovarian tumors; the result of this is edema and gangrene which may end in fatal peritonitis. Should the pedicle become completely separated, the nutrition may be maintained by the growth attaching itself to surrounding structures. Interstitial tumors are rarely single, and many times cause an enormous increase in the dimensions of the uterine walls. Submucous tumors are first attached by a broad base. Sooner or later pedunculation is produced by uterine contractions, though the size of the pedicle is most variable. They constitute the most frequent form of uterine polypi. The presence of these tumors acts as a foreign body and gives rise to uterine contrac- tions. There is, therefore, a natural tendency for the uterus to extrude them and force them into the vagina. Should the capsule rupture they may be expelled piecemeal or en masse, a process known as spontaneous enucleation (Hart). Degenerative Changes.-These are :— Suppuration; Softening; Induration; Calcification; Malignant degeneration. Suppuration.—Suppuration may follow or accompany any of the other degenerative changes mentioned. It occurs much oftener in submucous than in the other two varieties. Occa- 588 A TEXT-BOOK OF GYNECOLOGY. The most sionally it is met with in subperitoneal tumors. frequent cause of suppuration is interference with the circula- tion, resulting from uterine contractions. It may also be due to operative interference (Hart and Barbour). FIG. 128. 4638 A uterus with two large fibrous tumors, which were situated between it and the rectum. They had probably grown just beneath the peritoneum of the posterior wall of the uterus and are situated one above the other. The patient was 91 years old and carried the tumor for thirty-seven years. (Museum R. C. S. Photographed by the Author.) Softening. This results from fatty or myxomatous degenera- tion. Gusserow has found fatty degeneration in fibroid tumors. Myxomatous degeneration gives rise to spaces between the layers of the tumor, which become distended with mucus. This FIBROID TUMORS OF THE UTERUS. 589 is probably the beginning of so-called fibro-cystic tumors of the uterus. Edema is oftener due to twisting of the pedicle; when it occurs there is either a gradual or a rapid increase in the size of the tumor. Induration.-This change is connected with the menopause. It is probable that the atrophy and shrinking are due to the absorption of the muscular tissue with subsequent contraction of the fibrous (J. N. Simpson). FIG. 129. 4636 A uterus with the Fallopian tubes, ovaries, etc. A fibrous tumor of the shape and size of an ovary is attached by a broad band of peritoneum to the angle of the fundus of the uterus, near the right Fallopian tube. There are no interstitial tumors. (Museum R. C. S. Photographed by the Author.) Calcification. This results from a deposition of lime salts and is a species of calcareous infiltration. The growth is per- meated with phosphate and carbonate of lime. I have in my possession a tumor removed post-mortem which has completely undergone this change. The entire uterus is stone-like in hard- ness, and the sawed surface has the appearance of a calcareous mass. The process is similar to the transformation of pulmonary tubercles which undergo cretaceous degeneration. The resulting 590 A TEXT-BOOK OF GYNECOLOGY. changes impair the nutrition of the tumor, and the mass-the so-called womb stone of the older authors-may be expelled per vaginam. Not infrequently suppuration is associated with calcifi- cation. Malignant Degeneration.—I think that there is no doubt that fibroid tumors may undergo malignant degeneration. Such at least is the testimony of the majority of modern pathologists and gynecologists. A case is recorded by A. R. Simpson where the body of the tumor when cut into presented all the charac- teristics of a true fibroid. Several islands of sarcomatous degeneration were located in the midst of the fibrous tissue. In nearly all modern text-books can be found instances of similar cases. I had under observation for three years a case of fibroma of ten years' duration. It suddenly increased in size, and operative interference became imperative. An explo- ratory incision revealed not only malignant degeneration of the tumor, but of nearly all of the pelvic viscera. It is hardly probable that the growth could have existed so long had it been malignant from the onset. Martin (Annals of Gynecology for February, 1889) records six cases of fibroma uteri in which sarcomatous changes were met with. In all instances the patients had been under treat- ment by ergotine for a long time. This drug succeeded in every case in controlling the abnormal hemorrhages and in apparently reducing the volume of the growths. This same author also notes nine cases of myoma associated with car- cinoma. In some of the cases the carcinomatous disease had invaded the cavity of the uterus without extending to the tumor. Martin is of the opinion that myomas are never de- stroyed by carcinoma, though the two diseases may exist together. Cushing* has also recorded an instance of fibro-sar- coma of the uterus. Coe † and Liebmann ‡ have both observed uterine fibroids which have undergone cancerous degeneration, a microscopical examination showing groups of round cells invading the general fibrous structure. * Medical Record, May, 1889. † American Journal of Obstetrics, January, 1889. Centralblatt für Gynekologie, November, 1889. FIBROID TUMORS OF THE CERVIX. FIBROID TUMORS OF THE UTERUS. 591 When fibroid tumors are located in the cervix, they may spring from either wall and grow downward into the cellular tissue beside the vagina, or upward toward the peritoneal cavity (Fig. 130). They greatly distort the cervix and the pelvis, and, because of their low position, frequently become incarcerated. Some difficulty in diagnosis may arise from the danger of confounding them with inversion of the uterus (v. p. 571). Fortunately, they are rarely located in this region. FIG. 130. CO. FIBROID SPRINGING FROM POSTERIOR WALL OF CERVIX. Etiology.-It is possible to study only the circumstances under which fibroids appear, for, as to their exact cause, nothing certain is known. That there is an exaggerated local nutrition is un- questionable. But just why exaggerated local nutrition should in one instance produce fibroma, in another myoma, and in still another simple hyperplasia of the uterus, or simple hyper- trophy, it is hard to determine. From the fact that they are the most frequent new formations found in the uterus, it is evident that the cause, whatever it may be, is operative in many instances. It is estimated by Klob that fifty per cent. 592 A TEXT-BOOK OF GYNECOLOGY. of the women who reach the age of fifty have fibroma uteri. While this estimate is probably too high, there is no doubt, as is clearly shown by dead-room examinations, that a goodly per cent. of women of all ages have uterine fibroids, though in many instances their presence is not suspected during life. Under the head of predisposing causes it will be necessary to note :- Environment; Race; Age; Celibacy; Child-bearing; Menstrual disorders; Heredity. Environment.-Schroeder found in his polyclinic that among the poorer classes the proportion of carcinomas to myomas was as 100 to 61; in his private practice, which was largely among the wealthier classes, it was as 100 to 332. These statistics, as far as they go, show that fibroma is oftener met with in the higher walks of life and carcinoma in the lower. Race. It is said that the African race is particularly liable to fibroid tumors. Age.-The age of greatest sexual activity, 25 to 40, predis- poses to fibroma uteri. The larger number of cases occur be- tween the ages of 30 and 40.* When met with after the meno- pause, it is probable that in nearly all instances they have existed for some years previously to the cessation of the flow. Celibacy. The statistics of different authors are conflicting as regards the influence exerted by celibacy upon the production of fibroids. Emmet believes that celibacy predisposes to their for- * Gusserow's statistics :- Out of 919 cases 15 were below 20 years. 156" between 20 and 30 years. 357 338 30 40 40 50 36 12 50 " 60 60" 70 5 above 70 years. (Hart and Barbour.) FIBROID TUMORS OF THE UTERUS. 593 mation. On the other hand, of the 959 cases recorded by Gus- serow, 672 were married women. Child-bearing.-It has been observed that sterility frequently precedes the appearance of uterine fibroids. It was therefore supposed that the congestion incident to uninterrupted menstrua- tion predisposes to their formation. The more probable ex- planation is, that the tumor or tumors existed long before giving rise to symptoms attracting attention to the uterus, and were, therefore, the cause rather than the result of sterility. Menstrual Disorders.-The various menstrual disorders at- tended with congestion of the uterus and the pelvic organs pre- dispose to the formation of fibroids by bringing to the uterus exaggerated local nutrition. Here, as with sterility, it is difficult to determine in a given case whether the dysmenorrhea, which frequently precedes the detection of the tumor, is the cause or the result of the growth. Heredity. The statistics bearing upon this point are most unsatisfactory. It is probable that in the past hereditary influ- ences have been very much overestimated. Symptoms. These vary greatly in different cases. They are by no means dependent upon the size of the tumor; for a large growth may exist for an indefinite length of time without creat- ing the least distress, while a small one may cause the most excruciating pain. The symptoms can be advantageously studied under the fol- lowing heads:- Hemorrhage ; Leucorrhea; Dysmenorrhea; Pain and pressure symptoms; Sterility and abortion. Hemorrhage. Hemorrhage occurs either in the form of menorrhagia or metrorrhagia. It is much more profuse when the tumor grows toward the uterine mucosa. The blood does not proceed from the body of the tumor but from the en- dometrium, which is hypertrophied and frequently undergoes fungoid degeneration. It is probable, also, that there is more or less interstitial metritis attending the growth of the tumor, 38 594 A TEXT-BOOK OF GYNECOLOGY. which to a greater or less extent predisposes to hemorrhage. The patient often becomes greatly exsanguinated from the loss of blood, and even sudden death may be produced by it. In case of fatal hemorrhage the blood proceeds from a ruptured uterine sinus. The quantity of blood lost by no means depends upon the size of the tumor. A small polypoidal mass projecting into the uterine cavity will sometimes give rise to a most persist- ent flow of blood; whereas a large interstitial or subserous fibroid may not excite any hemorrhage whatever. Leucorrhea. The leucorrheal discharge, when it exists, is due to the same causes-endometritis and metritis-which produce hemorrhage. It is of a serous nature and, unlike that resulting from cancer, is odorless. Dysmenorrhea.—Painful menstruation results both from the mechanical pressure exerted by the tumor, and from the increased congestion arising from its presence. It is usually more severe in submucous growths, especially if pedunculation has begun. The pain is labor-like in character, and is due to exaggerated uterine contractions. In the interstitial and subserous varieties it is probable that the suffering results from the distention of the tumor with blood at this period (Gusserow). Pain and Pressure Symptoms.-Pain frequently results during the intermenstrual period, although it is usually aggravated by the onset of the catamenia. In those instances where the tumor is enclosed in a firm capsule and grows uniformly in all direc- tions, it is due to the tension attending the growth of the tumor. There is a sensation of increased weight and bearing down with large tumors. Excessive pain is often excited by the pressure of the tumor upon neighboring structures, and not infrequently extends down one or both thighs. Pain from this cause may be confined either to the anterior or the posterior surface of the limb, depending upon the nerves involved. The veins passing to the lower extremities may likewise be implicated sufficiently to produce varicosis. Occasionally the ureters are obstructed, though this accident occurs less frequently with fibroid tumors than with carcinoma; nevertheless, the pressure may be great enough to give rise to hydronephrosis. Dysuria from pressure upon the bladder or urethra is not an infrequent symptom. FIBROID TUMORS OF THE UTERUS. 595 If the tumor presses against the rectum, there will be constipa- tion, or, occasionally, diarrhea. All of the pressure symptoms are aggravated during menstruation. Should incarceration occur, complete intestinal obstruction may ensue. Sterility.—Sterility is present in about thirty-three per cent. of all cases of fibroids occurring in married women. Should conception take place, the presence of the fibroid will frequently cause abortion. Physical Signs.-Ordinarily the diagnosis is much more easily made than is the case with ovarian tumors. Great dif- ficulty may, however, sometimes arise, especially if inflammatory symptoms are associated with the fibroma. Small interstitial fibroids may escape detection. If the condi- tions are favorable, the bimanual will reveal an undue thicken- ing in some portion of the uterine wall. If in doubt, a sound should be used with the bimanual, when the thickening of the wall can be more readily detected. Should the tumor be located in the posterior wall, the unusual thickness of tissue intervening between the sound in the uterus and the finger in the rectum will be recognized; the localized hardness can also be deter- mined by the finger in the rectum. If pedunculated submucous fibroids do not project from the os, the cervical canal must be dilated. The finger can then be introduced into the uterus and the diagnosis readily made. Care must be taken not to confound this condition with inver- sion of the uterus (v. p. 571). The examiner will be called upon to distinguish small fibroids from- (a) Ante- and retroflexion.-In ante- and retroflexion the tumor, which is felt through the posterior vaginal fornix, will be penetrated by the sound. Unless the fundus is adhered, it can be lifted out of its unnatural site and the presence or ab- sence of a fibroid determined by practising the bimanual. (b) Chronic Metritis.-In chronic metritis there is usually more or less tenderness; the os is patulous and the uterus symmetrical. (c) Early Pregnancy.—If pregnancy is suspected the sound must not be introduced. The ordinary symptoms of pregnancy 596 A TEXT-BOOK OF GYNECOLOGY. are seldom wanting. The cervix is soft, and, indeed, the whole uterus when gotten between the two hands is much softer than it is in the case of fibroids. It is entirely possible for concep- tion to occur when the uterus contains one or more small fibroids. In the diagnosis of large fibroids it will be necessary to proceed systematically. The various conditions giving rise to distention of the abdomen are fully discussed in Chapter XLV. When the tumor passes into the general abdominal cavity there will be dulness on percussion over an area corre- sponding to its outlines, unless at a point where a loop of intestine intervenes between it and the abdominal wall. The growth is traced by palpation into the pelvis. There may be detected upon auscultation a bruit or souffle, which is due to the enlarged arteries and veins supplying the tumor. Upon vaginal examination a mass, more or less intimately connected with the uterus, will be found. It is continuous with it in inter- stitial and submucous growths, whereas in subserous fibroids with a long pedicle it is sometimes more difficult to determine the attachment to the uterus. Ordinarily, however, the tumor will move with the uterus when the latter is dragged down by means of the volsella. The sound will determine the length, direction, and distortion of the uterine canal. The length is not greatly, if at all, increased in subserous tumors; in the interstitial and submucous varieties the canal is usually not only increased, but greatly distorted as well. Large fibroid tumors may be confounded with- (a) Ovarian Tumors.-The history of menorrhagia is less marked and the uterus does not merge into the tumor, as is the case with fibroids. The uterine cavity is seldom, if ever, in- creased in size, and unless the tumor is attached to the fundus by adhesions the uterus moves independently of it. An ovarian cyst is more soft and elastic than is a fibroid. (b) Advanced Pregnancy.-The usual signs of pregnancy should be looked for: the uterus is of softer consistence; the fetal movements and heart-beats can ordinarily be detected; there is amenorrhea instead of menorrhagia. (c) Hematocele and Inflammatory Deposits.—In the case of FIBROID TUMORS OF THE UTERUS. 597 hematocele there will be a history of shock and collapse followed by inflammatory symptoms. If the tumor is due to inflam- matory deposits, the history of inflammation can be elicited. Both inflammation and hematocele may complicate fibroid tumors. (d) Cancer of the Uterus.—The pain is usually greater than in fibroid, the discharge more offensive, and the hemorrhage more irregular. In cases of suppurating submucous fibroids it may be necessary to resort to the microscope before an accurate diag- nosis can be made. Progress and Termination.-The clinical history of the ordinary hard fibroma and the rapidly-growing edematous myoma is usually very different. The former is hard, slow growing, and usually comes to a standstill at the menopause; the latter occurs at any age, the symptoms are more urgent, and it is seemingly not affected by the menopause or by the removal of the appendages (Tait). Should pregnancy occur in a uterus the seat of fibroid, the growth may increase in size with the development of the uterus. Occasionally, pari passu with the process of evolution, retro- grade metamorphosis, or even complete absorption, may take place. It is supposed that this is brought about by a process of fatty degeneration similar to that which the uterus under- goes during the parturient period (v. p. 610). Any of the forms of fibroids may delay the menopause in- definitely. When menstruation finally ceases, and senile uterine changes are established, the tumor ordinarily stops growing because of the diminished vascularity of the pelvic organs. Spontaneous cures sometimes result either by pedunculation and extrusion of the tumor as a polypus, or by disintegration, the fragments being expelled per vaginam. Spontaneous expul- sion in this way can only occur in interstitial and submucous tumors. It is brought about by the capsule giving way, usually the result of ulceration, the uterine contraction expelling the tumor either en masse or piecemeal. Prognosis. Uterine fibroids, if uncomplicated, rarely cause death. The prognosis is much more unfavorable when the mus- cular element preponderates than in the hard variety of tumor. 598 A TEXT-BOOK OF GYNECOLOGY. Death, when it results, may be due to hemorrhage, to uremia from compression of the ureters, to septicemia from suppuration and disintegration of the tumor, or to acute peritonitis. It be- comes necessary, therefore, in determining the prognosis in a given cease to note the variety of the tumor, its location in the pelvis, the age of the patient (the nearer she has approached the menopause the more favorable the prognosis), and the existing symptoms, of which hemorrhage is the most important. Gener- ally speaking, it may be said that, as regards life, the prognosis is favorable. The presence of the tumor, nevertheless, frequently gives rise to years of suffering and much anxiety. CHAPTER XXXIX. FIBROID TUMORS OF THE UTERUS.-(Continued.) TREATMENT. The treatment of fibroid tumors of the uterus resolves itself into (a) palliative and (b) curative. Palliative Treatment.-In by far the larger number of cases nothing more than palliative treatment is called for. This should be directed to the hemorrhage, to uterine displacements if they exist, and to the pressure symptoms. It is not always possible to control the hemorrhage even though all ordinary resources are exhausted. For its immediate control the recumbent posture, the internal remedy, the vaginal tampon, and the hot douche may be brought into requisition. The patient should, during the intermenstrual period, abstain from any cause tending to produce pelvic congestion. Sexual excess is for this reason pernicious. Constipation will likewise give rise to congestion of all the pelvic organs. Attention should also be paid to the functions of the liver and the skin. The remedies useful in polypi of the uterus, and in menor- rhagia and metrorrhagia from other causes, are the ones most frequently indicated in the treatment of hemorrhage resulting from uterine fibroids;* and the same principles of treatment adopted for the relief of menorrhagia due to endometritis are here applicable. I have more than once succeeded in control- ling hemorrhage for a greater or less length of time by the application of the sharp curette. This instrument is especially indicated if the presence of the tumor or tumors delays the menopause. In using the vaginal tampon it should be applied in a most thorough manner. The carbolized cotton may be soaked in a saturated solution of alum. In most instances the excessive * 7. pp. 252 and 624. 1 599 600 A TEXT-BOOK OF GYNECOLOGY. loss of blood can be controlled in this way. The hot douche, if its hemostatic properties are to be obtained, must be used in large quantities, and at a temperature of not less than 115°. A still more valuable palliative agent is electricity. I speak of it as a palliative agent only, because I believe that fibroids are rarely if ever entirely cured by its use. Electro-puncture, as practised by Apostoli, Englemann, and others, I never use. It seems to me infinitely more dangerous than laparotomy, but galvanism applied in the usual way will frequently do much good. The technique of its application is given in Chapter XI. It is only necessary at this time to add that benefit will often follow the use of the milder currents-80 to 100 milliamperes-con- tinued for a period of from two to six months. If carefully and intelligently localized within the uterus, a current of this strength is not dangerous and the benefit is often most marked. As a conservative measure, then, electricity, unless the case is an urgent one, should be faithfully tried before radical surgical treatment is decided upon. Surgical Treatment.-In interstitial and submucous tumors the hemorrhage may be controlled by incising the investing coat, the incision extending into the superficial layer of fibers. The practice inaugurated by Amussat, and popularized by McClintock, Nélaton, and others, of making incisions at the sides of the cervical canal is also recommended by certain authors. In both of these instances the hemorrhage is prob- ably relieved by diminishing the vascular supply of the uterus and tumor. Radical surgical treatment will vary according to the char- acter, the location, and the size of the fibroid. If it projects into the uterine cavity, and especially if pedunculation has taken place, it is entirely practicable, unless unusually large, to enucleate it through the vaginal and the cervical canals. However, when it is necessary forcibly to dilate the os, incise the capsule, and shell out the tumor; the operation is not only exceedingly difficult but hazardous as well. I confess that I undertake an operation of this kind with much more hesitancy than I do an abdominal section for the removal either of the entire uterus or its appendages. Nevertheless, when the tumor ព FIBROID TUMORS OF THE UTERUS. 601 E Lad makes its appearance at the external os, or is partially within the vagina, especially if the capsule is already disintegrated, an attempt should be made to enucleate and remove it per vaginam. The danger here is much less than would be incurred by abdomi- nal section. The Operation of Enucleation.—The patient should be prepared as for any capital operation. It is particularly important to have the bowels and bladder emptied. She may be placed either in the lithotomy or the Sims posture, as the operator may prefer. After being anesthetized, the parts are exposed by the aid of suitable specula and a careful exploration made. The surgeon should determine as accurately as possible the relation of the tumor to the interior of the uterus. Pressure from above by an assist- ant will crowd the uterus to the outlet of the vagina and will FIG. 131. > G. TIEMANN & CO GREENHALGH'S TUMOR FORCEPS. € greatly facilitate the operator's manipulations; it is even pos- sible to depress the uterus so far that a speculum is unneces- sary. The operator then grasps the cervix in a strong pair of volsella and makes a deep incision through the capsule with the point of a scalpel guarded by the finger. An effort is next made to peel the capsule from the tumor, which process is facilitated by grasping its edges with stout pressure forceps. The finger should be used as much as possible for this purpose. After the tumor is exposed it is seized with a pair of strong volsella (Fig. 131). By traction upon the handles of the volsella thus placed the tumor is drawn downward with a slight rotary movement, while the forefinger continues to detach the capsule. The various instruments devised for the purpose of aiding in the process of enucleation are exceedingly dangerous, and most 602 A TEXT-BOOK OF GYNECOLOGY. of the inventors have discarded their use. Thomas and Mundé state that they now use Thomas's well-known spoon saw much less frequently than formerly. The great danger attending the use of all such instruments is the liability of perforating the walls of the uterus. If the finger cannot reach far enough to complete the dissection, a strong steel male sound may be resorted to. By sweeping this over and around the tumor the deep lines of adhesion can be separated. If the tumor is very large it may be necessary to incise it by means of a scalpel or scissors before it can be delivered. Care must be observed, as the enucleation is about to be completed, not to invert the uterus by excessive traction. Should this accident occur, the attachments of the tumor should be cut away, the parts washed with an antiseptic solution, and the fundus returned to its normal position. It is sometimes exceedingly difficult to distinguish an inverted uterus from the tumor proper. After the enucleation is completed the capsule is washed with a 1:5000 bichlorid solution and the compound tincture of iodin applied to its entire inner surface. It is then packed with a strip of iodoform gauze, one end of which is left projecting from the vagina. This may be left in place for forty-eight, or, if the temperature does not rise, for seventy-two hours. At the end of this time the gauze is removed, and if no hemor- rhage takes place, the parts may be washed once or twice a day with a 1:5000 bichlorid solution. Should there be marked bleeding, it will be necessary again to introduce the gauze. The enucleation should be completed at one sitting if it is possible to do so. The exhaustion of the patient may compel the operator to desist before the mass is entirely enucleated. The danger from sepsis and hemorrhage is very great in incom- plete operations. The uterine cavity should, therefore, be washed at least twice a day with a two per cent. carbolic solution, and full doses of ergot given, with the hope of expelling the remainder of the tumor by inducing uterine contractions. Should sep- tic symptoms supervene, another attempt, which is usually successful, should at once be made to complete the enucleation. Fibroids of the cervix can nearly always be removed per vaginam. FIBROID TUMORS OF THE UTERUS. 603 ! Double Oophorectomy.—In July, 1872, Lawson Tait removed the appendages for the purpose of controlling hemorrhage caused by a bleeding fibroid tumor. The result was that in a few months the hemorrhage ceased and the patient recovered perfectly.* Up to three years ago Tait had removed the appendages in two hundred and seventy-two cases for the same purpose. He con- cludes most emphatically from his experience that oophorectomy, for the purpose of controlling the intractable hemorrhage result- ing from fibroids, is a perfectly justifiable procedure. As to the results, of the fifty cases recorded up to 1882 only two have proved to be failures. Of these, one was of the soft myomatous variety. Tait has met with six cases of myomatous tumors, none of which were benefited by oöphorectomy. Hegar also did much to popularize this method of treating fibroids. Oophorectomy for fibromata may be either very simple or very difficult. If the tumor is small the appendages are easily secured and removed. On the other hand when the tumor is large, and especially if complicated by adhesions, the difficulties may be not only very great but even insuperable. When one ovary is found it is wise to locate the second before securing the first, for but little relief would be afforded by the removal of one ovary only. If it is decided to proceed with the operation, the tumor is rotated in such a way as to expose as much as possible the append- age first to be removed. The pedicle is secured in a Stafford- shire knot and the appendage cut away. The second append- age is secured and removed in the same manner. The abdomi- nal wound is then closed in the ordinary way. Drainage is rarely necessary. • Laparotomy for the Removal of Fibroid Tumors.-Only a small per cent. of fibroid tumors give rise to symptoms sufficiently urgent to justify or demand laparotomy for their removal. The operation is not warranted at all until other resources having for their object the relief of the distressing symptoms have been exhausted. The conditions are very different from those which present themselves in ovarian tumors. As we have seen in * Birmingham Medical Review, May, 1889. †Thornton recommends that the first ovary be left intact until the second is secured and removed, so as to minimize the risk of bleeding from the first pedicle. 604 A TEXT-BOOK OF GYNECOLOGY. studying the prognosis of fibroids, death rarely ensues from the mere presence of a uterine fibroid. Then, too, the dangers attend- ing hysterectomy are infinitely greater than those attending ovar- iotomy. The average mortality in hysterectomy is from twenty to twenty-five per cent., whereas the mortality in ovariotomy is not over five per cent. This disparity is due to the greater diffi- culty in controlling hemorrhage in hysterectomy, the greater tendency to sepsis from sloughing of the pedicle, and the excessive shock incident to the removal of a large, solid tumor. Finally, as has been shown, the tumor usually ceases to grow after the patient passes through the climacteric changes. Therefore, so long as her life is not threatened or her health seriously im- paired by the hemorrhages or by the pressure symptoms, it is FIG. 132. От G.TIEMANN & CO TAIT'S CORKSCREW FOR HYSTERECTOMY. not necessary to interfere with the growth except in a pallia- tive way. On the other hand, should an interstitial or sub- peritoneal fibroid greatly interfere with the patient's comfort, or threaten life because of pressure or hemorrhage, laparotomy is indicated. After the abdomen is opened the choice between oophorectomy and the removal of the growth can be made. If the tumor is small and intimately attached to the uterus oophorectomy is undoubtedly-in the light of the statistics fur- nished by Tait, Hegar, and others—the preferable operation. If the tumor is large, and especially if it is of the soft, myomatous variety, it is best to end the laparotomy by removing it, together with as much of the uterus as may be necessary. FIBROID TUMORS OF THE UTERUS. 605 The patient is to be prepared as for ovariotomy. The ab- dominal incision is made in the ordinary way, except that in dealing with large tumors it is sometimes necessary to make it very long—even extending from the pubes to the ensiform cartilage. The tumor, if large, is lifted from the abdominal cavity by one or more corkscrews (Fig. 132). The surgeon will first observe the relation of the appendages to the tumor. Should the growth spring from the fundus of the uterus it probably has not carried the appendages with it and the ovaries and tubes will be found low down in the pelvis. On the other hand, if its ori- gin is in the lower uterine zone, the ovaries and tubes will be located high up at the sides of the growth. The bladder should be located by passing a sound into it. An elastic ligature (a piece of strong rubber tubing will answer every purpose) is thrown about the base of the tumor as far down on to the cervix as it is possible to place it. After this is drawn tight and secured in the blades of a strong pair of catch forceps, the hemor- rhage will be entirely under control. As a general rule this ligature will include the ovaries and tubes; should it not, it will be necessary to ligate and sever the appendages separately. Instead of the elastic ligature some operators prefer to use for temporary constricting purposes either the clamp or the serre- nœud. The tumor is now cut away, two or three inches above the elastic ligature, after which the stump is cared for by one of two methods presently to be described and the abdomen closed. The after treatment does not differ essentially from that which follows all abdominal sections. Management of the Pedicle.-A great variety of methods have been introduced for the management of the pedicle. They resolve themselves naturally into the extra- and intra-peritoneal methods. Hegar's is probably The elastic ligature, purpose of tempor- Of the various extra-peritoneal methods the most simple and the one oftener used. which was placed about the pedicle for the arily controlling the hemorrhage, is left permanently in situ. The stump is then secured in the lower angle of the wound, the parietal peritoneum being stitched to that covering the pedicle below the ligature. If necessary the ligature may transfix the 606 A TEXT-BOOK OF GYNECOLOGY. pedicle instead of encircling it (Fig. 133). To prevent retrac- tion and slipping of the ligature, it is best to transfix the pedicle FIG. 133. a EXTRA-PERITONEAL METHOD OF TREATING PEDICLE. (Hegar.) (a) Method of closing abdominal wound; (6) Method of transfix- ing pedicle by elastic ligature. above the ligature by a couple of strong transfixion needles passed transversely. The ends of the elas- tic ligature are permanently secured by a strong piece of silk. As much of the stump as can be is now ex- cised, after which it is cauterized either by a saturated solution of chlorid of zinc or by the Paquelin. The elastic ligature usually comes away about the eighth or tenth day. Pean's Method.-The serre-naud is used instead of the elastic ligature. The wire of the serre-noud is kept from slipping by two steel pins placed above it. The stump is secured in the lower angle of the wound, ex- actly as in the method of Hegar, except that the two opposing peri- toneal surfaces are not stitched to- gether. The cautery is applied to the surface of the stump. Bantock's Method. I will describe Bantock's method as he himself has carried it out many times in my pres- ence. A temporary elastic ligature is thrown around the tumor as low down as it is possible to apply it. Frequently it includes the upper portion of the vagina. The upper half of the tumor is then cut away, leaving a stump at least four inches long. A longitudinal incision is made anteriorly through the peritoneum and underlying muscular layer, extend- ing downward as far as the internal os. The peritoneum, together with its subjacent structures, is next stripped from the stump to a point corresponding with the lowest point of the incision in front. The wire of the serre-naud is placed around the stump thus FIBROID TUMORS OF THE UTERUS. 607 created, but does not include the peritoneum. Transfixing pins are placed above the wire, when the stump is trimmed. The elastic ligature is now removed. There is left, as it were, a hood of peri- toneum encircling the stump. This is stitched to the parietal peritoneum by quilted silkworm-gut sutures, underneath which are placed strips of iodoform gauze to prevent cutting. This hood of peritoneum not only shuts off the stump entirely from the peritoneal cavity, but catches any discharge that may drop from the stump proper. Any excess of peritoneum which projects above the surface of the abdominal wall is cut away. This operation is ingenious and, in the hands of Bantock, most satisfactory. It is, however, a much more difficult opera- tion than are Hegar's and Péan's, and, even in the hands of its originator, the time required for its completion is much greater. Bantock packs about the stump iodoform gauze. If the bleeding is profuse and is not controlled by the serre-naud, he carries deep sutures under the bleeding points, and ties them. Intra-peritoneal Treatment of the Pedicle.-The mortality attending ovariotomy fell at once after the intra-peritoneal treat- ment of the pedicle became popular. There are many objec- tions to the extra-peritoneal method of treating the pedicle in hysterectomy. It is necessary for the stump to slough before the ligature or serre-nœud cuts its way through. This is always attended with danger of sepsis, though the disintegrating process is without the peritoneal cavity. The convalescence is much more tedious than is the case in ovariotomy when the pedicle is returned to the abdominal cavity. Then, too, a vagino-abdom- inal fistula occasionally results, requiring for its closure a second operation. These various objections have induced operators to experi- ment with the intra-peritoneal method of dealing with the pedicle; and, indeed, some operators do away with the pedicle entirely by removing with the tumor the whole uterus, together with the cervix.* Those who have especially popularized the * In subserous fibroids, when the pedicle is small and easily secured, all authorities agree that the proper way of dealing with it is to secure it in a ligature and return it to the abdomen, as in ovariotomy. I once returned to the abdomen a pedicle nearly 608 A TEXT-BOOK OF GYNECOLOGY. intra-peritoneal method are Schroeder, Kelley, Sanger, Byford, and Baer. Schroeder was one of the first operators who practised the intra-peritoneal method of dealing with the stump. He proceeds as follows:- The broad ligaments and vessels are secured on either side of the tumor with a double thread and divided. The elastic liga- ture is then thrown about the stump thus formed, and the tumor removed. A transverse wedge of tissue extending downward to the elastic ligature is next excised from the stump; the cer- vical mucous membrane is exsected with this. All vessels are secured with catgut ligatures. The stump is then closed by a continuous catgut suture, which is buried in the tissues, the peritoneum being brought together over its sur- face by interrupted silk sutures. The elastic ligature is finally removed, the parts thoroughly cleaned, and the stump dropped into the peritoneal cavity. same. The operation of Schroeder has been modified by various surgeons, though the principles observed by all are much the A decided innovation has recently been made by Baer of Philadelphia. This operator secures all of the vessels of the broad-ligaments in ligatures, and does not pass a single liga- ture into or about the cervical tissue proper. The stump is completely covered by the taut folds of peritoneum left behind. In the extra-peritoneal treatment of the stump the pedicle is separated by pressure necrosis. In order to prevent the tissues from actually putrefying, various means have been resorted to. Bantock simply applies absorbent wool, and maintains that this alone is quite sufficient. Applications of tannin, alum, and strong perchlorid of iron are used for the same purpose. The elastic ligature keeps up a continuous tension, which controls the hemorrhage and promotes the separation of the stump. If the serre-nœud is used, a few turns of the screw should be made every second or third day, or oftener should there be any evi- dences of hemorrhage. Gauze, which should be frequently changed, is kept packed around the pedicle so as to absorb all three inches in diameter, after transfixing it with an elastic ligature (Medical Coun- sellor, 1887.) The patient recovered without any untoward symptoms. Neverthe- less, this practice should be limited to pedicles not larger than an inch in diameter. FIBROID TUMORS OF THE UTERUS. 609 discharge. After the separation of the pedicle there is left a deep granulating excavation. Ordinarily this becomes level with the skin in the course of a week or ten days, and in the course of another week or two skins over. It sometimes becomes necessary to combine the intra- and extra-peritoneal methods of treating the pedicle. In conduct- ing the combined treatment where the pedicle cannot be brought outside of the abdominal cavity without exerting too much tension upon it, it is first secured by one or more ligatures, the ends of which are fixed in the inferior angle of the wound so that the pedicle is suspended from them. The serre-nœud or elastic ligature may be used in the same way. The pedicle is drawn for some distance into the abdomen and its margins stitched to the parietal wound, so that the discharge cannot escape into the abdominal cavity. Bantock's method of deal- ing with the pedicle leaves behind a sufficient amount of peri- toneum to permit of the adoption of this method very nicely, should it be necessary. Some operators have surrounded it with mackintosh sheeting in order to shut it off from the general peritoneal cavity (Greig Smith). As regards the relative mortality of the two methods, intra- and extra-peritoneal, the advantages are as yet all on the side of the latter, notwithstanding its many objections. This is shown by the following table taken from Pozzi:- a. INTRA-PERITONEAL METHOD. Number of Deaths. Operations. b. EXTRA-PERITONEAL METHOD. Number of Deaths. Mortal- Operations. Mortal- ity. Per Cent. ity. Per Cent. Gusserow, 19 31.6 Kaltenbach, 5 3 60.0 Martin, 86 15 17.4 Bantock, . Hegar, Kaltenbach, 22 2 9.0 22 6 27.0 22 I 4.5 Olshausen, 29 9 31.0 Keith, • • 38 2 5.3 Spencer Wells, 26 ΙΟ 38.0 Péan, • 52 18 34.0 Schroeder, 135 4I 30.0 Tauffer, 17 2 11.7 Tauffer, 12 4 33.0 312 88 24.10 Spencer Wells, 20 Lawson Tait,. 54 Thornton, 10 50.0 20 37.0 • 15 2 13.0 262 63 19.15 Myomectomy.—Myomectomy, or the enucleation of large sub- peritoneal and interstitial fibroids through the abdominal cavity, 39 610 A TEXT-BOOK OF GYNECOLOGY. was first introduced and popularized by A. Martin of Berlin. He operates as follows: After controlling the hemorrhage by a temporary elastic ligature, he splits the capsule by a long incision, turns out the tumor, closes the capsule by stitching its edges together with interrupted sutures, and, if it approaches the vagina, drains through this canal. Myomectomy is especially useful when the tumor is located deep in the folds of the broad ligament. These tumors have no pedicle and cannot be dealt with in the ordinary way. Instead of closing the capsule, as recommended by Martin, and draining from below, it may be stitched to the abdominal incision, as recommended for incomplete ovariotomies, its cavity being tightly packed with iodoform gauze. However, when the whole uterus can be removed and the pedicle dealt with according to the extra-peritoneal method, this is the preferable procedure. Vaginal hysterectomy may be resorted to if the tumor is not too large. Removal of Fibroids During Pregnancy.-Fortunately, the vic- tims of uterine fibroids are frequently sterile. When conception does occur, peculiar dangers attend gestation. Early abortions, which are of frequent occurrence, must be reckoned among these dangers, although premature expulsion of the ovum is in such cases to be accounted a piece of good fortune. Pregnancy in most instances causes the tumor to grow very rapidly, so that pressure symptoms soon become marked. This is especially true of interstitial fibroids and fibroids springing from the cer- vix. Not infrequently the growth undergoes edematous soften- ing. The treatment will be determined by the circumstances. In the case of pedunculated sub-mucous fibroids which project into the vagina, the pedicle should be ligatured and divided. Should the growth spring from the cervix and grow toward the vagina, an attempt may be made to enucleate it without interrupting gestation. Small subserous and interstitial tumors, situated high up, may be left unmolested if the pressure symptoms are not distressing, with the hope that pregnancy may proceed to term. On the other hand, if life is threatened by the impulse which the growth of the fibroid has received, it will be necessary either to provoke a miscarriage or to open the abdomen. If the FIBROID TUMORS OF THE UTERUS. 611 physician is inexperienced in abdominal surgery it will probably be safer for him to empty the uterus if it is possible to do so. There is, however, very great danger of fatal hemorrhage fol- lowing this course. In two cases coming under my observation the hemorrhage was only controlled by applying powerful styp- tics directly to the endometrium. Had I again to contend with similar cases I should pack the uterus with iodoform gauze. Supravaginal amputation, in the hands of an experienced ab- dominal surgeon, is, in my opinion, attended with little greater danger than is the induction of abortion. Indeed, in large tumors laparatomy is usually called for in the end, in order to relieve the embarrassed organs. In this connection, the following case is both interesting and instructive: On November 15, 1893, Prof. N. Schneider of Cleveland, requested me to see with him a young woman twenty-eight years of age, whom he saw for the first time three days previously. She had been married six months, and the menses had been suppressed for four months. Her abdomen was enormously enlarged, emaciation was extreme, and the digestion and circulation were greatly embarrassed. The abdominal enlargement was symmetrical but peculiar. It was almost pyramidal, the umbilical region being the most prominent. The tenderness was very marked. Digital examina- tion revealed the cervix in the hollow of the sacrum and to the left, and almost obliterated. The finger could only penetrate the external os. In the anterior fornix a large globular mass, con- tinuous with the tumor above, could be distinctly felt. Whether the body felt was an extra-uterine fetus, an intra- uterine fetus, or an adventitious growth we could not determine. The patient declared that she felt motion up to two weeks before the examination was made. There was no history of false labor and no history of shock and collapse, such as usually attend primary rupture in extra-uterine pregnancy. The fetal heart sounds could not be heard. As a girl, the abdomen was en- larged, though the menstrual discharge was never excessive. It was clearly evident that the patient was dying from the exhaustion induced by the pressure of the tumor, whatever its nature. She was removed to the Huron Street Hospital in an ambulance and placed under an anesthetic on November 17th, 612 A TEXT-BOOK OF GYNECOLOGY. two days after our first examination. An attempt was first made to dilate the cervix and explore the uterine cavity. The sound penetrated the uterus for a distance of two inches, but, for reasons which will appear later, the fetus could not be felt with the finger. Accordingly, after plugging the uterus and vagina with gauze the abdomen was opened. The incision, which was central, brought into full view the tumor shown in Fig. 134. FIG. 134. A PREGNANT UTERUS, TOGETHER WITH A SUB-SEROUS FIBROID WEIGHING TWENTY-FOUR POUNDS, REMOVED BY SUPRA-VAGINAL HYSTERECTOMY. THE BRISTLE PENETRATES THE CERVICAL CANAL. (Wood.) An incision extending from the pubes to the ensiform cartil- age was required in order to deliver it. The uterus contained a four months' fetus and the cervix contained a second tumor as large as a fetal head. This was why the finger could not penetrate the uterine cavity. Several smaller tumors projected from the surface of the fundus. There was but one thing to do under the circumstances, namely, remove the uterus and appen- dages with the tumor. In this opinion Prof. Schneider con- FIBROID TUMORS OF THE UTERUS. 613 curred. This was done by first throwing about the cervix, low down, an elastic ligature. The cervix was then amputated above the ligature, after which the serre-naud was applied and the ligature removed. The abdomen was washed with sterilized water and the utero-vesical pouch, which continued to ooze blood, was tamponed according to the method of Mikulicz. This was the only form of drainage used. The abdomen was closed in the usual way. The patient rallied from the operation but died thirteen hours later from shock. I firmly believe that had the abdomen been opened a month earlier her life might have been spared. The case is a most interesting one for several reasons: It illustrates the impulse given to the growth of fibroids by pregnancy; it illustrates the difficulties which may attend the diagnosis of rapidly growing tumors complicating pregnancy; finally, it illustrates also the difficulties and dangers which may be encoun- tered in attempting to empty the uterus through the cervical canal. Unless the pedicle is very small in subserous and interstitial tumors, I think that supravaginal amputation is safer and more satisfactory than is simple myomectomy. FIBRO-CYSTIC TUMORS OF THE UTERUS. Fibroid tumors of the uterus may, as we have seen, undergo degeneration and form cysts, or, rather, pseudo-cysts. The result- ing fluid is not included in a special cyst wall, hence the term "cystic," as applied to these growths, is somewhat misleading. This form of degeneration is of rare occurrence, although it may take place in any fibroid tumor of the uterus. Its cause is uncertain. Koeberle suggests a possible lymphatic origin in certain instances. Whatever the cause, serum finds its way between the bundles of fibrous tissue throughout the mass. The spaces thus formed are divided by septa or trabeculæ, which in time become broken down, producing one or more large cavities. Subserous fibroids oftener undergo cystic degeneration. The symptoms do not differ essentially from those of large fibroids in general. It is maintained that the health of the patient is less often seriously affected than is the case with solid 614 A TEXT-BOOK OF GYNECOLOGY. tumors (Thomas and Mundé). If the cavity, or cavities, are at all large, fluctuation may be detected. It is then extremely difficult to differentiate fibro-cystic tumors from ovarian cysts. As a rule, the differentiation is not made before the abdomen is opened, the surgeon until then thinking that he has to do with an ovarian tumor. Even if tapping is resorted to there is nothing pathognomonic about the character of the fluid. It was claimed by Atlee that fluid which coagulates as soon as exposed to air, and in which is formed a colorless blood-clot, is suffi- ciently characteristic to distinguish fibro-cystic tumors of the uterus from ovarian cysts. Later observation has not confirmed this claim. The examiner will, then, be led to suspect the presence of a fibro-cystic growth when a large, indistinctly fluctuating tumor exists for a long time without seriously compromising the general health of the patient; when physical exploration con- nects such a tumor with the uterus; when the uterus is drawn upward toward the abdominal cavity; and, finally, when the uterine cavity is markedly increased in size. The uncertainty of diagnosis previously to opening the abdomen is, notwithstanding the foregoing symptoms, usually very great. The treatment does not differ from the treatment of fibroids in general, except that the attachments in fibro-cystic tumors are usually more extensive and the vascularity greater. Should extirpation prove too hazardous after the abdomen is opened, the cyst cavity may be stitched to the abdominal wall, as is recommended in incomplete ovariotomy. The cavity is then packed with gauze. As a palliative measure, tapping may be resorted to when more radical treatment is not expedient. This, however, should never be done if it is possible to remove the tumor without too great risk. Electricity is entirely inapplicable in dealing with these growths. # CHAPTER XL. POLYPI OF THE UTERUS: THERAPEutics of UTERINE FIBROMA AND POLYPI. Varieties. Since the term polypus, as ordinarily applied, signifies the form of tumor only, it is proper to include under the head of polypi of the uterus the following varieties:— 1. Fibrous polypi, which are pediculated submucous fibroids in the process of extrusion; 2. Mucous polypi, springing from the mucous membrane ; 3. Enlarged cystic follicles, which have become pediculated; 4. Placental polypi, the result of the retention of a portion of the placenta, following abortion or labor at term. I. Fibrous Polypi.-Fibrous polypi are nothing more than fibroid tumors forced into the uterine cavity by uterine contrac- tions. They have their origin in the muscular walls of the uterus, in the larger number of instances springing from its body. When incised, they show the same firm consistence as do fibroid tumors. They vary in size from that of a walnut to that of an adult head, and are usually of a symmetrical or pyriform shape. Fig. 135 shows such a polypus yet within the uterine cavity. Fig. 136 shows a tumor partly projecting from the external uterine orifice, while Fig. 137 shows one completely extruded from the vagina, with the pedicle much elongated and con- stricted by pressure. After the polypus passes into the vagina, if large, it may inter- fere with the functions of the bladder and the rectum. Occasion- ally the tumor becomes adhered to the vagina, suggesting that the growth is of vaginal origin. In the preceding chapter it was noted that when an intersti- tial fibroid grows toward the uterine cavity it excites uterine contractions, by which process pediculation and extrusion are accomplished. As the tumor becomes more and more poly- 615 616 A TEXT-BOOK OF GYNECOLOGY. poidal in shape, the uterus becomes less and less tolerant of its presence. The length of the pedicle varies greatly. It may not be long enough to permit the polypus to be forced from the uterus, or its length may permit it to hang without the vagina. FIG. 135. 4608 A UTERUS CONTAINING A FIBROUS TUMOR IN THE PROCESS OF PEDICULATION. (Museum R. C. S. Photographed by the Author.) Fibrous polypi are, as a rule, sparingly vascular. The men- orrhagia and metrorrhagia, which so frequently result from their POLYPI OF THE UTERUS. FIG. 136. G.D. 617 SUBMUCOUS FIBROUS POLYPUS PROJECTING INTO VAGINA. (Auvard and Devy.) FIG. 137. FIBROUS POLYPUS SPRINGING FROM CERVIX. (Wood.) The patient suffered for six years with a tumor of some kind within the vagina which was supposed to be prolapsus uteri. The tumor escaped from the vagina three days before I saw her, when, owing to constriction, it rapidly enlarged and became exceedingly offensive. The temperature at the time of entering the hospital was 106°, but quickly dropped to normal after the mass was removed. 618 A TEXT-BOOK OF GYNECOLOGY. presence, are due to the existing endometritis, the blood pro- ceeding from the uterine mucous membrane. 2. Mucous Polypi.-These are oftener located in the cervix. They rarely attain a size larger than that of a walnut, and usually are smaller than this. They are of a soft, pulpy consist- ence. Unlike fibrous polypi, they are extremely vascular, and are made up, histologically, of the same structure as that of the mucous membrane from which they spring. Occasionally, microscopical section shows also stratified epithelium similar to that found in the vaginal portion of the cervix. FIG. 138. When this VASCULAR MUCOUS POLYPUS GROWING FROM INNER WALL OF UTERUS. (Museum R. C. S. Photographed by the Author.) epithelium is found these growths may be the starting point of malignant disease (Underhill). When they spring from the body of the uterus, the ducts and cysts are lined with ciliated, cylindrical epithelium (Hart and Barbour). Fig. 138 shows a very large mucous polypus springing from the body of the uterus. This location, as already indicated, is most unusual. Fig. 139 shows the usual appearance of these growths when located in the cervix. They are rarely single, and frequently as many as eight or ten exist together. POLYPI OF THE UTERUS. 619 3. Enlarged Cystic Follicles which have become Pedicu- lated. These have already been referred to under the head of cystic degeneration of the cervix (v.p.431). They are known also as glandular polypi. They are merely hypertrophied Nabothian follicles distended with fluid. More or less hypertrophy of the cervical canal attends their growth. The glands of the body of the uterus proper may likewise undergo degeneration. Such a condition is shown in Fig. 140. These polypi rarely become larger than a bean, though they may reach a size equal to that of a pullet's egg. They are usually of a benign character. FIG. 139. FIG. 140. MUCOUS POLYPI. (Schroeder.) ENLARGED PEDICULATED CYSTIC FOLLICLES. (Beigel.) A few cases are reported where these growths, springing from the cervix, have developed to a size sufficient to fill the vagina, and even to protrude from the vaginal orifice. When they attain this size they are made up of tissue partly glandular, partly colloid, and, in nearly all instances, partly malignant or sarcoma- tous. Pfannenstiel * reports a most interesting case of this kind. The patient was 53 years of age and had always been healthy. Five years after the menopause she began to have local distress. An examination revealed a polypus springing from the anterior *Münchener Medicinische Wochenschrift, September, 1891. 620 A TEXT-BOOK OF GYNECOLOGY. cervical wall which extended to the vulva. The tumor con- sisted of a grape-like mass. It was removed with a sharp spoon curette and its base seared over with the Paquelin. A micro- scopic examination showed it to be sarcoma. The entire uterus was then removed per vaginam, but the growth returned six months later in the left half of the vaginal cicatrix. Up to that date the author was able to find recorded in the literature only eleven cases of the kind. Thomas, Mundé, and Fenger, of this country, have each reported similar cases. * 4. Placental Polypi.-These are formed by the incomplete detachment of the placenta, a few of the villi remaining behind. Around this small mass of placental tissue blood coagulates and fibrin is deposited. Polypi of this origin may continue to increase in size until a tumor of some dimensions is produced. This condition is classified under the head of "Polypi," simply because of the shape of the tumors formed; they are not new formations. Symptoms.-Hemorrhage is the most frequent and constant symptom. In fibrous polypi it is due to the endometritis result- ing from the presence of the tumor; in mucous polypi it pro- ceeds from the tumor itself as well as from the hypertrophied uterine mucous membrane. It manifests itself first in a gradual increase in the menstrual flow; and as time goes on it may become intra-menstrual, not infrequently exsanguinating the patient. The quantity of blood lost by no means depends upon the size of the tumor, a very small mucous polypus giving rise to profuse and even fatal hemorrhage. The anemia induced by the loss of blood is, in some cases, * Under the head of “Adenoma of the Uterus," Coe (Journal of the American Medical Association, July, 1891) states that there is but one variety of true cervical ade- noma, and that is malignant. This assertion is based upon the fact that the disease is not confined to the mucous membrane, but invades the underlying muscular layers. The growth of the tumor is exceedingly slow. It is, nevertheless, fatal unless removed. Coe advises total extirpation as the only treatment to be considered; curetting appears to hasten the tendency to malignancy. Pozzi also includes under the head of cancer of the corpus uteri adenoma of the uterus. Malignant adenoma is, according to the author last named, the initial process of cancer of the mucosa. There yet exists more or less confusion relative to these growths of the uterus. POLYPI OF THE UTERUS. 621 most striking-at times suggesting the cachexia of carcinoma. Should an offensive leucorrhea accompany the hemorrhage, there is danger of mistaking it for malignant cachexia. The next most constant symptom is leucorrhea. Like the hemorrhage, it is due to the existing endometritis. It is rarely offensive except when the polypus sloughs. Menstruation is often most painful. The suffering is due to the polypus interfering with the exit of the menstrual blood, as well as to the exaggerated uterine contractions resulting from the presence of the tumor. Sterility must also be included under the head of symptoms. It is due both to mechanical causes and to the endometritis. Diagnosis.—If the tumor does not protrude from the uterine cavity into the vagina, it will be impossible to determine the cause of the uterine enlargement without first dilating the cervical canal. Sometimes the tumor presents at the external os only during menstruation. It is, therefore, well to make an examina- tion at this time when the presence of a polypus is suspected. In fibrous polypi a bimanual examination will show that the uterus is enlarged. After the cervix is dilated the finger and sound will indicate the situation of the pedicle, as well as its size. Should the polypus be of placental origin, it is easily detached by a dull wire curette. It is rarely necessary to dilate the cervix in dealing with this form of polypi. Mucous polypi springing from the cervix can ordinarily be detected by digital examination. Their characteristic form and color will be observed after the speculum is introduced. There will be no difficulty in detecting the presence of a fibrous polypus when it finds its way into the vagina. There is, however, some danger of mistaking a large polypus thus located for an inverted fundus uteri. This mistake has more than once been made. The uncertainties are increased when inflammation and adhesions exist. In order to differentiate the two conditions let the examiner proceed as follows:— First, determine if possible, the location of the fundus uteri by abdomino-vaginal examination. If it is in its normal position the vaginal tumor is probably a polypus. Should it be an 622 A TEXT-BOOK OF GYNECOLOGY. inverted fundus, and the conditions are favorable, the truncated end of the uterus may be detected through the abdominal wall. If the abdominal walls are unusually thick or tender, so that the bimanual is unsatisfactory, the sound may be passed into the bladder and the finger into the rectum. In this way the pre- sence or absence of the fundus between the finger and the sound can be determined. If the tumor within the vagina is a poly- pus, and adhesions do not exist between its pedicle and the cervix, the sound will penetrate the uterine cavity for at least two and a-half or three inches; if it is an inverted fundus, the sound cannot be passed. It must not be forgotten that a partial inversion is frequently associated with a polypus. Prognosis. The prognosis, in the absence of malignancy, is usually favorable. If the polypus endangers life it is because of the hemorrhage excited. Mucous polypi springing from the cervix are removed with but little difficulty. The removal of fibrous polypi may be attended with greater risk. Ordinarily, however, when pediculation is complete there is no special difficulty attending their removal. Treatment. This is entirely surgical. A polypus of any de- scription should be removed as soon as it is discovered, unless urgent counter indications exist. Mucous polypi may be seized with a pair of strong catch forceps and twisted off or excised. It is my practice to touch the base of a tumor thus removed with the Paquelin cautery. Placental polypi are easily removed with a curette, after which the uterine cavity should be cleaned and the compound tincture of iodin applied.* In dealing with fibrous polypi it is important to determine accurately the location and size of the pedicle. The cervix may be dilated, either rapidly under ether, or by the use of tents. Personally, I prefer the rapid method. If it is possible to locate the pedicle, it may be divided with curved scissors guarded by * Rosenburg reports, in the Internationale Klinische Rundschau, November, 1889, a case of abortion at the sixth month, where the placenta could not be removed and became septic. As a forlorn hope, vaginal hysterectomy was performed. The patient made a speedy and perfect recovery. POLYPI OF THE UTERUS. 623 the finger, or with a polytome (Fig. 141). Unfortunately, this can- not always be done, the size of the tumor interfering with the manipulations. In this event, if the pedicle is not too thick, it may be separated by torsion. When cutting instruments are used great care must be observed not to injure the walls of the uterus, the scissors or polytome at all times hugging the surface of the tumor. The possibility of a partial inversion should constantly be borne in mind, for there is always danger, when this compli- cation exists, of cutting into the uterine tissue. The old practice of separating the pedicle by ligature or écraseur is now practi- cally abandoned. If the écraseur is used, it is better to connect the wire with the galvano-cautery. A very large tumor may so interfere with intra-uterine and intra-vaginal manipulations as to make it necessary to incise the mass before attacking the pedicle. FIG. 141. TIEMANN-CO-NY AVELING'S POLYTOME. Should the hemorrhage not be controlled by the cautery, gauze packing may be resorted to. I think that it is entirely possible to relieve by internal medi- cation many of the distressing symptoms, particularly the hemorrhages, which are incident to uterine fibroma and polypi. Whether or not these growths can be actually cured by internal medication is a question about which there is a wide difference of opinion. I cannot better express my own views on this sub- ject than to quote the words of Dr. Ludlam. He says: He says:* "In claiming that these tumors are curable in their incipiency by means that are so mild and variable, I do not forget that there are many sources of failure which might lead to a wrong infer- ence respecting the efficacy of this entire plan of treatment. It *" Medical and Surgical Lectures on the Diseases of Women." 1888. 624 A TEXT-BOOK OF GYNECOLOGY. is not unusual for these growths to increase or decrease in size very rapidly, and sometimes to disappear spontaneously. A retrograde metamorphosis may take them out of the way, the climacteric may arrest their development, and other changes may cut off their nutrition and cause them to wither. These cures by limitation are often placed to the credit of such agencies as animal magnetism, spiritualism, electricity, and other imponder- ables, even of medical treatment. But making due allowance for all these exceptional cases, I apprehend it remains that very great good of a positive kind may be done by means of fitly chosen in- ternal remedies." Therapeutics of Uterine Fibroma and Polypi. Lachesis.-Uterine region feels swollen; will bear no contact, not even of the clothing; bearing down pains; uterine and ovarian pains relieved by the flow of blood; leucorrhea copious, smart- ing, stiffening the linen and staining it greenish; suitable at the menopause, with flushes of heat, hot vertex, metrorrhagia, and fainting.* Belladonna.-Much bearing down in the pelvis; metrorrhagia of bright red blood, or thick, decomposed, dark red blood; the genital organs are sensitive, and there is much throbbing in them; plethoric patients; menses too early and too profuse. Calcarea iodid.-Menses too early, too long, and too pro- fuse; acidity of the stomach; milky leucorrhea, with itching and burning.† *“ Lachesis seems possessed of remarkable virtues as a resolvent, particularly where there is defective involution of the womb."- Ludlam. "The indications for Calcaria iodid in the treatment of uterine myomas are not well understood. It seems to be more effectual in causing a gradual diminution of the tumor than any other remedy, and in doses too small to act on the theory of calcifi- cation of the growth and interference with its nutrition. It is significant that the most celebrated mineral waters for the cure of fibroids contain a large amount of lime salts. Good results have been reported from the third decimal trituration. It has also been recommended in the shape of ten grains to a pint of water, a teaspoonful to be taken after each meal, gradually increasing to a tablespoonful. This may act very similarly to chlorid of calcium in possibly causing a calcareous degeneration of the tumor; but, as it has been found that the coats of the arteries are also likely to undergo the same degeneration, the remedy may become a dangerous one. It seems quite probable that it can influence the nutrition or development of these tumors in a certain number of cases without being given in a sufficient quantity to induce the degeneration alluded to."--Southwick. THERAPEUTICS OF UTERINE FIBROMA AND POLYPI. 625 Secale cor.-Menses too profuse and last too long, with tear- ing and cutting colic; cold extremities; cold sweat; great weak- ness and small pulse. Passive hemorrhage of fetid or dark blood; leucorrhea, brownish and offensive.* Trillium.-Gushing of bright red blood from the uterus on the least movement; weak sight; anxious look; patient is pale and faints easily; flow returns every two weeks. † Ferrum.-ANEMIA FROM LOSS OF BLOOD; sticking, shooting pains in the uterus; menses too late, too long lasting and pro- fuse; the flow is watery and preceded by labor-like pains; hysterical symptoms after menses; alternate redness and paleness of face. Sabina. Menses too profuse and too early, with colic and labor-like pains in uterus; stitches from below upward in vagina; metritis with hemorrhages; blood dark and corroding and some- times offensive. China.-Uterine hemorrhages of dark, clotted blood, with fainting and muscular twitching; prostration from loss of blood. Platina.-Painful sensitiveness in the region of mons veneris and genital organs; induration of uterus and frequent sensations as if the menses would appear; pruritus vulvæ; voluptuous ting- ling with anxiety and palpitation of the heart; vulva painfully sensitive during coitus. Plumbum.-Hemorrhage with sensation of a string pulling from the abdomen to the back; climacteric period; dark clots alternating with fluid blood or bloody serum, with a sensation of fulness in pelvis. * “ I have frequently obtained temporary ameliorations of the symptoms produced by the pressure of a fibroid with an apparent shrinking of the tumor by the use of Secale cor. in a low attenuation. The drug is, however, usually given by hypodermic injec- tions in from three to six drops of Squibb's solution two or three times a week. Simpson recommends the following formula :— Ergotinæ, Aquæ, Chloral hydrate, zij 3 vj 3 ss. Mix. Twelve minims of the solution to be used at each injection.". Cowperthwaite. † “Trillium seems to be especially adapted to the menorrhagia and metrorrhagia which are almost always present in cases of interstitial and intrauterine fibroids, for, like Secale, it is of little use in uterine hemorrhage unless, from pregnancy or otherwise, the muscular fibers of the womb have been decidedly developed."-Ludlam. 40 626 A TEXT-BOOK OF GYNECOLOGY. Sulphur.-Menses too late and of short duration, or sup- pressed; before menses headache; cough in the evening; nose- bleed; bearing down in pelvis toward genitals; stitches or pressing pain in region of liver; constipation, stools hard, knotty, insufficient; skin rough and scaly. Conium mac.-Induration and prolapsus of the uterus with lancinating pains; acrid and burning leucorrhea, preceded by pinching pains in abdomen. Kali hydriod.-Fibroid tumors with much emaciation and prostration; menorrhagia; dysmenorrhea, and constant leucor- rhea. Ledum.-Fibrous tumors with menorrhagia; displacement of uterus; profuse leucorrhea; abundant urination. Silicea.-Amenorrhea with great debility; profuse, acrid, ex- coriating leucorrhea; morbid perspirations. Consult.-Sabina, hamamelis, pulsatilla, nitric acid, calcaria carb., china, ipecacuanha, and sepia. CHAPTER XLI. MALIGNANT DISEASES OF THE UTERUS. CARCINOMA OF THE CERVIX. General Considerations and Etiology. It is estimated that cancer of the uterus is located in the cervix in 97 per cent. of all cases met with. It is also estimated that of the total male mortality death is due to carcinoma in about 0.97 per cent. of all cases, whereas among women it is the cause of death in 2.2 per cent. of all cases.* Notwithstanding this great disparity, the mortality of the two sexes from carcinoma is the same pre- viously to the age of puberty. After this period the relative proportion of female to male mortality from this disease gradu- ally rises until the age of fifty, at which time it reaches its maximum in women. Cancer is located in the uterus in one-third of the total cases occurring in women. Next in frequency, as regards location, are the mammary glands. Various theories have been put forth by different pathologists to explain the great predisposition of the cervix to malignant neoplasms. It is suggested by Cohnheim that the embryonic cells (embryo-plastic cells of Robin) which are found dissemi- nated throughout the connective tissue, or accumulated at certain points, constitute the fundamental tissue of carcinoma. The involution of the blastodermic layers is more irregular at the natural orifices of the body, and, therefore, these orifices are the seats of predilection for nests of embryo cells. The cervix, developed relatively late from Müller's tubes, is particularly rich in these nests of embryo cells. There also exist at the cervical opening two kinds of epithelium, which create a tend- ency to plastic paramorphism (Pozzi). These peculiarities, it is claimed, make the cervix congenitally vulnerable to the invasion of carcinoma. * Hart and Barbour, “Manual of Gynecology," 1883, p. 436. 627 628 A TEXT-BOOK OF GYNECOLOGY. In addition it will be necessary to note as predisposing factors:- Heredity; Age; Childbearing; Race; Depreciation of vital forces. Heredity.—Undoubtedly the importance of hereditary influen- ces has been greatly over-estimated in the past. According to Gusserow, it has been proven to exist only in about 7.6 per cent. of all cases; Schroeder places the estimate at 8.2 per cent. ; and Winckel at 6.3 per cent. The statistics bearing upon this sub- ject have been largely drawn from hospital cases, and hospital patients, it must not be forgotten, often know very little of their antecedents. Age. The larger percentage of cases occur between the ages of forty and fifty. I will again quote from Gusserow. These statistics should be compared with those of fibroid tumors given on page 592. Gusserow's statistics:- Out of 2270 cases 2 were under 20 years, 81 between 20 and 30 years, 476 "" 30 40 66 771 66 600 258 "6 (6 40 50 "60 50 60 (6 70 82 over 70 years. (Hart and Barbour.) It will be observed from the foregoing that the number of cases occurring under the age of puberty (two) is very insignifi- cant; yet cancer of the uterus has been discovered in children. Mundé has met with a case in a girl of eighteen, and Zweifel removed the uterus, per vaginam, from a girl of thirteen for epithelioma of the cervix. Childbearing.-Winckel's statistics show that of multiparous women victims of cancer the average number of children was 8.2 per cent. Hofmeyer, in a series of 812 cases of carcinoma, found only 4.8 per cent. of nulliparæ. In Winckel's series of cases sterility was present only in 1.7 per cent. It is observed by most authorities that miscarriages and abortions frequently precede carcinoma of the uterus. MALIGNANT DISEASES OF THE UTERUS. 629 Race.—The African race, although especially liable to fibroma uteri, seem to enjoy greater immunity from carcinoma of the cervix than do other races. Kelley has recently reported two cases of cancer of the cervix in negresses.* Depreciation of Vital Forces.-Unlike fibromata, carcinomata occur much oftener among the poor than the rich. This is probably due to the depraved nutrition so much more preva- lent among the former class, as well as to the greater physical exertion and exposure to which they are subjected. Of the exciting causes, anything that will keep up an active irritation tends to produce a rapid production of cells and papillæ. If constant stimulation and irritation are kept up by any of the enumerated causes, carcinoma is liable to result, particu- larly in one predisposed to it. Cervical lacerations cause an eversion of the mucous membrane, and subject it to constant friction against the vagina as well as to irritation during coitus. Protracted catarrh will likewise perpetuate irritation and congestion. It is probable that the frequent occurrence of lacerations and cervical catarrh following parturition is the reason why cervical cancer occurs oftener in multiparæ. The deposition of cicatricial tissue unquestionably plays an important part in the production of malignancy. Varieties and Pathology.-Any of the following forms of cancer may attack the cervix :- Encephaloid or soft cancer; Scirrhous (fibrous or hard cancer); It is often Epithelioma (superficial or epithelial cancer). 'This division is, to a large extent, arbitrary. impossible to determine the original form of the disease after the tissues are broken down. The distinction between encepha- loid (medullary), and scirrhous cancer, is largely one of degree. In the former, the cellular element predominates; in the latter, the fibrous stroma. According to Thiersch and Waldeyer these two forms have their origin in epithelial cells (either the squamous which cover the vaginal surface of the cervix; or the cubical which line the cervical canal). According to Virchow, they start from the connective tissue cells of the cervix. *"Transactions of the Southern Surgical and Gynecological Association," 1891. 630 A TEXT-BOOK OF GYNECOLOGY. Epithelioma of the cervix occurs in two forms: (1) The flat, which gives rise to superficial ulceration within the canal and causes excavations. (2) The papillary (Fig. 142), which springs from the deep layers of squamous epithelium on the vaginal aspect of the cervix (Thiersch and Waldeyer); this, FIG. 142. 4661 EPITHELIOMA OF THE CERVIX. A ligature is tied around a part of its base, its substance having been broken through. The uterus is enlarged and its cavity dilated; on its left wall there is a small flat growth, half an inch in diameter, like a mucous polypus. The ovaries are both adherent to the sides of the uterus and the broad ligaments are thickened. (Museum R. C. S. Photographed by the Author.) instead of excavating the cervical canal, grows downward into the vagina in the form of a cauliflower excrescence. Encephaloid and scirrhous cancers grow very rapidly, quickly invade the con- nective tissue, and produce early metastasis. On the other MALIGNANT DISEASES OF THE UTERUS. 631 hand, epithelioma progresses slowly, spreads by extension, and does not produce metastasis until late. Symptoms. The symptoms vary greatly in different cases. One of the earliest and most constant is hemorrhage. If the patient has passed the menopause, it is often noticed for the first time after straining at stool or after coitus. Before the meno- pause it frequently begins as a menorrhagia, menstruation sooner or later becoming irregular without any apparent cause. It occurs earlier in epithelioma growing toward the vagina. During the first stages it proceeds from the vascular stroma of the growth, the numerous delicate vessels readily rupturing. Later on, if profuse, it is due to destruction of one of the larger vessels. Immediate death rarely, if ever, is caused by the hemorrhage. The next most constant symptom is a vaginal discharge. This frequently alternates with menorrhagia. At first it is watery and not particularly offensive. After necrosis of tissue takes place it is tinged with blood, and possesses a most penetrating and offensive odor. This odor cannot well be described, yet it is peculiarly characteristic, and when once observed will be readily detected. The leucorrhea becomes excoriating, and the irritation of the vulva and thighs is sometimes very great. Decomposing blood-clots and threads of gangrenous tissue are often expelled with the discharge during the later stages of the disease. Pain does not occur until infiltration of the adjacent structures takes place. There is nothing about the pain of carcinoma that is characteristic, although it is usually spoken of as shooting, lancinating, or stabbing in character. The patient not infre- quently locates it in the center of the pelvis, from which it radi- ates to the lower portion of the back and groins, or extends down the inner sides of the thighs. Unlike the pain of chronic inflammation of the uterus it is usually aggravated at night. It is often most distressing and even insupportable. Cachexia sooner or later makes its appearance. It is due to the absorption of débris, to the exhausting serous discharge, and to the hemorrhage which so frequently attends the disease. In time a malignant toxemia is induced, due to the diminution of the albumin and red blood corpuscles, with an increase in the 632 A TEXT-BOOK OF GYNECOLOGY. watery constituents of the blood. As a result the skin takes on a peculiar sallow, or dirty straw-colored tint. Early and progressive emaciation is very characteristic of can- cer. The nutrition becomes seriously impaired. This is due to various causes, one of the chief being the offensive fetor result- ing from the discharge. The disease frequently involves the bladder and the rectum, seriously interfering with the functions of both of these organs. When it extends toward the bladder dysuria may be the first symptom calling the attention of the patient to the pelvic organs. Not infrequently the ulceration extends into the bladder and a vesico-vaginal fistula is thus formed. If the rectum is invaded defecation becomes painful, or even impossible. Physical Signs.-Unfortunately, in by far the larger number of cases, the physician does not have an opportunity to practise physical exploration until after the disease is considerably ad- vanced. Few women deem an examination necessary until some of the symptoms which have been studied make their appearance. The disease during its early stages will be found almost invariably located at the external os; thence spreading, as the case may be, upward along the cervical canal, downward into the vagina, or into the deeper tissues of the cervix. After the stage of ulceration, the finger will feel an irregular surface with hard, unyielding margins; or, in the case of papillomatous tumors (cauliflower excrescences) a soft, friable mass projecting into the vagina. Upon withdrawing the finger it will be stained with blood and the characteristic odor will be recognized. In scirrhous cancer, the cervix is increased in size, its surface is irregular or nodulated, and the tissues are indurated. The tender- ness is not marked. The mucous membrane covering the diseased area is fixed to the underlying tissues. The experienced examiner will be able to obtain more definite information from digital exploration than from a specular examination. Great care must be observed in using the specu- lum after the ulcerative process has begun. The irregularly ulcerated surface, with unyielding margins, will be seen through the speculum; or, should the case be one of cauliflower excrescence, a papillomatous mass will project into its field. MALIGNANT DISEASES OF THE UTERUS. 633 In case of doubt, the final test must be the microscope. If a portion of the tissue is removed and prepared for microscopical examination, there will be found irregular cells of an epithelial type, with one or more large nuclei, surrounded by a fibrous stroma with alveoli. These cells are characterized by their large size and by their prominent round or oval nuclei, which con- tain one or more bright red nucleoli. It is the mode of distri- bution of the cells in the meshes of the fibrous stroma that determines malignancy; there is no pathognomonic cancer cell. While the foregoing symptoms are characteristic of a typical case of cancer of the cervix, it is necessary to remind the reader that the disease may reach an advanced stage before any of the symptoms enumerated make their appearance. The pain may be nearly or entirely absent. The offensive discharge is not always present, even when there exists necrosis of tissue. Hem- orrhage is by no means a constant symptom. The physician should, therefore, be upon his guard. Since vaginal hysterec- tomy has become a popular and beneficent operation, it is all- important that an early diagnosis should be made. Slight, irreg- ular hemorrhages, occurring during the inter-menstrual period, or after coitus, call for immediate local examination. If, upon making such an examination, there should be found induration of the cervix with an easily bleeding erosion, a wedge-shaped portion of tissue should be excised for microscopical examination. Differentiation.-The conditions which simulate cancer of the cervix are :— Syphilitic ulceration; Areolar hyperplasia of the cervix ; Papillary erosion, with ectropium and cicatricial deposits; Sloughing fibrous polypus; Retention of the products of conception; Sarcoma of the cervix. Syphilitic Ulceration.-Syphilitic ulceration of the cervix is a very rare condition. Usually there is present condylomata. This condition yields to proper treatment. The constitutional manifestations of the disease are rarely wanting. Areolar hyperplasia of the cervix and papillary erosion, with ectropium, resemble carcinoma only at the beginning of the latter 634 A TEXT-BOOK OF GYNECOLOGY. disease. If an immediate diagnosis is important the microscope should be resorted to. If the chances are that the condition is not malignant, proper treatment may be prescribed; this will improve both areolar hyperplasia and papillary erosion. The well-known test of Spiegelberg should also be applied. In carci- noma there is, according to Spiegelberg, fixation of the mucous membrane to the underlying indurated tissues; and rigidity of the cervix. The last-named condition is indicated when an effort is made to dilate the cervix by means of laminaria tents. Sloughing Fibrous Polypus.-The tissues are firmer and do not break down as easily as does carcinomatous tissue. The mass is more sharply defined, because the surrounding structures are less infiltrated. Retention of the Products of Conception.-These lie loosely in the cervical canal and are easily detached. It should not be forgotten that carcinoma may make its first appearance during the puerperium. Sarcoma of the Cervix.-Sarcoma of the cervix is an exceed- ingly rare condition. As in sarcomatous tumors in other parts of the body, it grows more slowly than does carcinoma. It is impossible to make a positive differentiation without resorting to the microscope. Practically, the distinction between the two affections is not important, for the treatment is the same in both. Progress of the Disease.—In cancer of the cervix the blad- der is implicated in about 40 per cent. of all cases. It first invades the cellular tissue between the bladder and the uterus, finally attacking the mucous membrane. Fistulæ result in 20 per cent. of all cases. The ureters are still more frequently disturbed. Complete obliteration of one or both ureters occurs in 50 per cent. of all cases. Infiltration takes place, either at the opening of the ureters into the bladder, or higher up at the sides of the cervix. Occasionally the bladder, rectum, and vagina are converted into a common cloaca. The peritoneal cavity is rarely opened into. As the disease advances a protective lymph is thrown out, and adhesions form between the peritoneum and uterus. The extent and direction of the invasion are well shown in Figs. 143, and 144. MALIGNANT DISEASES OF THE UTERUS. 635 Prognosis. The prognosis, as regards life, will depend largely upon the progress made by the disease when first de- tected. During its early stage the general opinion is that cancer is a local disease. If this opinion is correct, and judging from the large number of operative cases now on record it is, it means that cancer may be cured provided all of the diseased FIG. 143. MEDULLARY CANCER OF CERVIX INVADING THE VAGINA. The cervix is entirely ulcerated away, and the bladder is also implicated. The body of the uterus appears healthy, though the ovaries are adherent to it. (Museum R. C. S. Photographed by the Author.) tissue can be removed. So long, therefore, as it is confined to the uterus, and does not involve the surrounding structures, it is curable. Unfortunately, the surgeon does not meet with it at this stage, except in a very small per cent. of cases. It will take another decade to educate the general profession to the importance of early diagnosis in carcinoma uteri. 636 A TEXT-BOOK OF GYNECOLOGY. After the disease is no longer confined to the uterus the prognosis is preeminently unfavorable. Its duration is most variable-from six months to four or five years. The average duration is two years; it will, how- ever, depend upon the succeeding complications liable at any time to arise. Cause of Death.-Exhaustion is one of the most frequent causes of death. It is due to hemorrhage, to leucorrhea, and FIG. 144. A UTERUS, THE CERVIX OF WHICH, TOGETHER WITH A PART OF THE VAGINA, IS DESTROYED BY CANCEROUS ULCERATION. The ovaries are slightly enlarged, and their surfaces are puckered. (Museum R. C. S. Photographed by the Author.) to the compromised and impaired nutrition. The last condition is due to an inability to take food, as well as to the exceedingly offensive odor almost never absent. Uremia is the next most frequent cause of death. It results from the occlusion of the ureters. Peritonitis occasionally ter- minates life, though general peritonitis is of rare occurrence. When it does occur as a complication, it is due to a sudden giving way of adhesions, with consequent contamination of the MALIGNANT DISEASES OF THE UTERUS. 637 peritoneal cavity. Hemorrhage, as has already been shown, rarely, if ever, causes immediate death; the long-continued drain will, however, greatly prostrate the patient and hasten fatal exhaustion. Venous thrombosis may result in sudden death by the formation of emboli, or it may give rise to phlegmasia dolens. Finally, death may result simply from the absorption of septic products derived from the breaking down of tissue. CARCINOMA OF THE BODY OF THE UTERUS. The statistics of Schroeder show that cancer is located in the body of the uterus in less than two per cent. of all cases. The observation of more modern writers is not in harmony with this statement. It is probable that formerly many cases of carcinoma of the body of the uterus were overlooked for the reason that explorative dilatation and curetting were less frequently practised than at the present time. Pathology. The disease originates either in the mucous membrane or in the uterine parenchyma. When it springs from the mucous membrane it projects into the uterine cavity in the form of a soft, friable mass; when it has its origin in the uterine parenchyma, localized nodules project either toward the mucous membrane or the peritoneal surface. The various etiological factors enumerated under carcinoma of the cervix apply to carcinoma of the body of the uterus, except that the larger number of cases occur between the ages of fifty and sixty instead of between forty and fifty. A much larger per cent. of cases also occur in nulliparæ. Symptoms.-Pain is a much earlier and more constant symptom than is the case with carcinoma of the cervix. It is severe, intermittent, and lancinating in character. Hemorrhage is also a more prominent symptom than in car- cinoma of the cervix. It is at first due to the increased vascularity of the endometrium; later, it is caused by the break- ing down of tissue. The characteristic cancerous discharge follows necrosis of tissue. In time the cancerous cachexia manifests itself. Physical Signs.-The bimanual will show enlargement of the uterus. There is more or less induration with tenderness on • 638 A TEXT-BOOK OF GYNECOLOGY. pressure. Unless implicated in the cancerous process, the cervix is free from disease, although the os is often patulous. The introduction of a uterine sound gives rise to hemorrhage. Carcinoma of the body of the uterus will have to be distin- guished from- Retained portions of placenta and cystic degeneration of the chorion; Fungoid endometritis ; Fibroid tumors and large fibrous polypi; Sarcoma of the uterus. As regards the first three conditions, pain is seldom severe; the discharge, except in the first, is not offensive. Upon making a microscopical examination of the products obtained by curet- ting the evidences of malignancy are wanting. Fibroid Tumors and Large Fibrous Polypi.-These growths are more liable to be mistaken for carcinoma while undergoing degeneration. There will be a history of menorrhagia long continued. The uterine sound will show an increased depth of the cavity of the uterus. Hemorrhage does not attend the passing of the sound. If the cervix is dilated, the finger will fail to detect the soft, fungoid, carcinomatous mass projecting from the mucous membrane. Before the ulcerative process has set in, it is extremely difficult to differentiate between carcinoma springing from the substance of the uterus and fibroids. In case of doubt the microscope should be resorted to. The most expert microscopist cannot determine with absolute certainty the presence or absence of malignancy by a micro- scopical examination of curettings alone. The products removed are often so insignificant that a simple glandular hypertrophy attending endometritis may be distinguished with difficulty from cancer. The whole depth of the uterine gland, or glands, can rarely be obtained by curetting, and the diagnosis will often have to rest upon probability rather than certainty. Therefore, in those cases where the hemorrhage persists in spite of repeated applications of the curette, as well as other recog- nized therapeutic measures, and where the cause of the hemor- rhage is evidently not disease of the uterine appendages, it may be wise to resort to vaginal hysterectomy, particularly if the MALIGNANT DISEASES OF THE UTERUS. 639 patient is approaching or passing through the so-called cancer- ous age. I have removed the uterus in at least three cases for persistent hemorrhages of this nature after an experienced microscopist had failed to obtain from the curettings positive evidences of cancer After its removal, the uterus showed in each instance unmistakable evidences of malignancy. Progress. As the disease progresses it frequently involves the cervix and neighboring organs. Perforation occasionally occurs into the peritoneal cavity, setting up peritonitis. Metas- tasis to distant organs may also result. Prognosis. If the condition is detected early the prognosis is more favorable than in carcinoma of the cervix, for the reason that there is less likelihood of the surrounding structures being involved. If not interfered with, the prognosis is grave. Death is due to the same causes enumerated under the head of cancer of the cervix. SARCOMA OF THE UTERUS. Sarcoma, according to Cohnheim, is a connective-tissue tumor of an embryonic type. Sarcomatous tumors were formerly known as recurrent fibroids. When met with in the uterus they occur in two forms: (1) Diffuse sarcoma of the mucosa; (2) fibroid sarcomatous tumors. Sarcoma is rarely located in the cervix. Diffuse Sarcoma of the Mucosa.-The proliferation of round or fusiform cells infiltrates the mucous membrane, and gives rise to thickening. In time there appear “soft, villous, or lobulated tumors, having an encephaloid aspect, and reproducing an embryonic type of connective tissue." (Virchow.) These fungoid masses are soft, irregular, and easily broken down. In appearance they are grayish white. Deep excavation of the mucous membrane does not occur, as in carcinoma. Sometimes there are found mixed tumors composed of the histological characteristics of carcinoma and sarcoma. A microscopical examination of the mucous membrane will reveal masses infil- trated with closely set round cells, with occasional spindle cells. Fibroid Sarcomatous Tumors.-These growths, like benign fibroid tumors, may be either interstitial, subperitoneal, or sub- 640 A TEXT-BOOK OF GYNECOLOGY. mucous. It is maintained by some authorities that they are nothing more than malignant fibroid tumors. They arise in the uterine parenchyma, but their isolating capsule is not distinct, and they are deeply rooted. On section their consistence is soft and homogeneous. Occasionally they undergo degeneration, and are converted into muco-sarcoma or cysto-sarcoma. Etiology.—While the larger number of cases occur at or near the menopause, numerous instances of sarcoma of the uterus have been met with in women under twenty years of age. Of seventy-five cases analyzed by Gusserow, twenty-five were childless, four of the twenty-five being virgins. This contrasts markedly with carcinoma of the cervix and body of the uterus. Symptoms. The symptoms of diffuse sarcoma of the mucosa do not differ essentially from those of carcinoma of the body of the uterus. There is an increase in the volume of the affected organ. A serous discharge, alternating with hemorrhage more or less profuse, is a frequent, though not a constant, symptom. Cachexia is of later occurrence than in carcinoma of the uterus. Pain is not an early symptom. There is also less fetidity of the flow during the early period, and ulceration does not set in until late. In the beginning of fibroid sarcomatous tumors there is nothing to distinguish them from benign fibroids. There is hemorrhage, odorless hydrorrhea, some pain from pressure, and an increase in the size of the uterus. After ulceration of the neoplasm occurs, the hemorrhage becomes more profuse and the leucor- rhea offensive. The discharge contains peculiar, rice-like masses, which are broken down sarcomatous tissue. Inversion of the uterus not infrequently results in consequence of sarcoma. There is a complete fusion of the tumor with the contiguous tissues, which makes enucleation impossible. Repeated recurrences after removal are a peculiar feature of sarcoma. Metastatic deposits have been found in the lungs, liver, vertebræ, and lymphatic glands. CHAPTER XLII. MALIGNANT DISEASES OF THE UTERUS.- (Continued.) TREATMENT If it be true that carcinoma is, at its beginning, a local affection, becoming general only as it extends by contiguity of tissue, or by the absorption of broken-down débris, the possibilities of curing the disease depend entirely upon an early diagnosis and early operative interference. This applies to carcin- oma wherever located, but emphatically so to carcinoma of the uterus, because with no other removable organ of the body is it so difficult to reach beyond the parts primarily affected. The surrounding glands cannot be enucleated; it is only possible to remove a certain amount of tissue. That the disease does, at the beginning, localize itself in the uterus, is, I think, clearly proved by the large number of operative cases now on record. Nevertheless, it is an unfortunate fact that at least seventy-five per cent. of all cases of carcinoma and sarcoma of the uterus will have passed beyond the operative stage before coming under the observation of the specialist. The treatment, then, naturally resolves itself into- (a) Palliative; (b) Curative.* Palliative Treatment.-This will include the management of the hemorrhage, the pain, and the leucorrheal discharge. The hemorrhage can often be favorably influenced by the use of the indicated remedy. I have but little faith in the action of large doses of ergot for this purpose, especially when the * In the treatment of the various malignant affections of the uterus, I have deemed it best to consider under one head carcinoma and sarcoma of both the fundus and the cervix. The same principles of treatment are applicable to the several forms of malignancy, whether the disease is located in the body or the neck of the organ. 4I 641 642 A TEXT-BOOK OF GYNECOLOGY. disease is limited to the cervix. If the indicated remedy is not sufficient, and the hemorrhage is great enough to exhaust the patient or to threaten her life, local medicaments must be used. One of the least objectionable of these is the saturated solution of alum; and the patient should always have at hand a sufficient quantity of this agent to use whenever necessary. Cold water may be resorted to for the same purpose. Should the hemor- rhage still persist, a tampon, saturated with a weak solution of perchlorid of iron may be placed against the bleeding surface. To obtain the mechanical effects of the tampon, others must be packed about it in such a way as to exert decided pressure upon the cervix (v. p. 150). Should the hemorrhage proceed from the body of the uterus, a solution of alum, heated, may be injected into the cavity. The nurse should be instructed as to the methods of con- trolling hemorrhage, especially if the patient reside some distance from the attending physician. The patient should be advised to abstain from sexual intercourse and to observe care in straining at stool. Indeed, constipation should always be guarded against, for if the rectum is distended with hard fecal matter it not only adds greatly to her distress, but predisposes to hemorrhage. After infiltration of tissue, pain becomes the most prominent and most distressing symptom. When the disease is confined to the cervix, much relief may be afforded by the local use of anes- thetic and narcotic agents. Iodoform is not only a powerful disin- fectant, but it is also a local anesthetic of much value. It may be applied directly to the parts by means of a powder blower; or it may be mixed with almond oil (13–31) and applied by means of a tampon. The fluid extract of opium, either in the form of suppositories or applied directly to the ulcerated sur- face, is beneficial. The fluid extract of belladonna is also a use- ful agent, particularly if the pain is of a throbbing character. Suppositories composed of one grain of the fluid extract of opium and one-quarter of a grain of the fluid extract of bella- donna is an old and well-tried method of using these agents com- bined. Equal parts of chloroform, glycerin, and sweet oil is another old formula and at times a most useful one. (Ludlam.) TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 643 This preparation may be applied by means of a tampon. A solution of hamamelis, or a saturated solution of hydrate of chloral, may afford relief when other remedies fail or their effect becomes exhausted. In contending with pain, invaluable service may be obtained from the properly selected remedy. The physician is urged to withhold the internal administration of opium as long as it is possible to do so without permitting his patient to suffer too greatly. It is even claimed by some of the best men in the homeopathic school that the use of opium is never necessary in contending with pain of any kind. I cannot refrain from con- gratulating the prescriber who is sufficiently skilled to dispense with the use of this agent in the disease under consideration. No one deprecates more than I the internal administration of opium, especially in cancer. I am nevertheless compelled to admit that during its later stages I am many times unable to control the almost intolerable suffering incident to it without resorting to some of the forms of opium. Its use is attended with unpleasant consequences which I should be only too glad to avoid. These consequences are, however, in my opinion, more than offset by the relief afforded. The disease, after reaching a certain stage, is inevitably fatal, and it has always seemed to me that it is the duty of the physician to bring to its victim all possible means of relief. If he cannot keep her comfortable without the use of opium, I believe he should administer it in doses sufficiently large to accomplish the desired end. However, the drug should not be given until it is abso- lutely necessary; it quickly exhausts itself and will have to be repeated in ever-increasing doses until the amount required is sometimes enormous. It is best administered hypodermatically. The leucorrheal discharge is to be contended against by the frequent use of antiseptic and disinfecting fluids. Of these a solution of permanganate of potash is one of the best. It should be used as a douche (20: 1000), and repeated as often as neces- sary. After the parts are cleansed with this solution, an iodo- form suppository containing two grains of iodoform may be introduced into the vagina. Carbolic acid (one to fifty) is also a powerful disinfectant, and possesses anesthetic proper- 644 A TEXT-BOOK OF GYNECOLOGY. ties as well. A solution of thymol (five per cent.) or bi- chlorid of mercury (1:5000) may also be used for this pur- pose. Hot water alone, administered in large quantities, will not only cleanse the parts, but will many times greatly relieve the suffering (v. Chapter X). Erythema of the vulva, during the later stages of cancer is often most distressing. The parts should be protected by some of the ointments recommended for pruritus vulvæ. Equal parts of olive oil and lime-water applied to the vulva will often afford marked relief. A solution of chlorinate of soda is also highly recommended by some writers. A more formidable palliative measure, which is surgical in its nature, is curetting. It is especially useful in those cases where the disease is made up of soft, friable masses projecting either into the uterine cavity or from the cervix. The hemor- rhage, the offensive discharge, and the pain, are largely due to these papillomatous growths. If removed by the curette, the relief afforded is often most marked. The hemorrhage is tem- porarily controlled, the offensive discharge ceases for a greater or less length of time, and the pain is most decidedly ameliorated. Moreover, the symptoms of sepsis, due to the absorption of necrosed tissue, will disappear for the time being. As a pallia- tive measure, then, the use of the curette is of the first impor- tance. In most instances I deem it best to place the patient under the influence of an anesthetic before the curette is applied. There should be at hand the various preparations of iron for the purpose of controlling hemorrhage, as well as a Paquelin cautery. After the speculum is introduced, the cervix is supported by the volsella, and Simon's sharp spoon curette is expeditiously but thoroughly applied, all of the necrosed tissue being scraped A stream of hot bichlorid should be kept playing upon the parts during the operation, as the hemorrhage is usually very profuse. The raw surface is now seared over with the Paquelin cautery. Ordinarily, this will control the hemorrhage; if not, a solution of perchlorid of iron may be applied. A strip of iodoform gauze is finally carried into the uterus if the case is one of carcinoma of the body, or packed into and about the away. TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 645 cervix if the disease is limited to the neck. Additional strips of gauze are packed into the vagina. These can be left in for two or three days, after which they are removed and the parts kept thoroughly clean by antiseptic and disinfecting injections. Besides the various local measures which have been enume- rated, it is important to maintain the nutrition of the patient by nourishing food and by proper hygiene. Owing to the offensive discharge, the sick-room should be kept thoroughly ventilated; if the patient can have at her command two rooms, so that one can be aired while she is occupying the other, such an arrange- ment will be advantageous. It seems unwise to inform the patient that she is the victim of incurable malignant disease, unless it is absolutely necessary because of business affairs, to do so. If the facts are known to her the effect upon the mind is most distressing. Since she is liable. to live for months, or even for years, there is no reason why she should be informed of the inevitable end. Of course her immediate friends should be made familiar with the diagnosis and prognosis-this for the physician's protection. Again, it is never wise to prophesy too closely as to the probable duration of life. The physician can only state the average duration of the disease, at the same time emphasizing the fact that certain complications may suddenly terminate life. Therapeutics. Arsenicum alb.-Cancer of the uterus, with burning, agoniz- ing pain, and secretion of fetid, brown or blackish ichor; faint- ness; BURNING PAINS, even felt while sleeping; ACRID AND CORRODING LEUCORRHEA; emaciation, with excessive debility; restlessness; symptoms of septicemia.* Hydrastis Can.-Ulceration of cervix and vagina, with sym- pathetic affections of the digestive organs; the discharge is tena- cious, thick, and ropy; pruritus vulva, with sexual excitement. Conium mac.-HARDNESS OF UTERUS, WITH INTOLERABLE LANCINATING PAINS THROUGH THE PELVIS; acrid, burning leucor- rhea, preceded by pinching pains in abdomen; carcinoma form. *If the induration and hardness are marked, Arsenicum iod. is the preferable 646 A TEXT-BOOK OF GYNECOLOGY. following chronic inflammation and induration of ovaries; scanty menstruation, especially in sterile women. Kali bich.-Leucorrhea yellow and ropy, with pain and weakness across small of back; dull, heavy pains in hypogas- trium. Phytolacca. Menses too frequent and too copious; metror- rhagia; ropy leucorrhea toward morning; hunger soon after eating; urine dark-red, with painful micturition. Thuja.-CAULIFLOWER EXCRESCENCE PROJECTING FROM CERVIX; erosions of os uteri; aphthæ. Graphites.-Violent lancinating, stitching pains through the uterus down to the lower extremities; inclined to obesity, with a history of delayed menstruation; swelling of the feet; the discharge is glutinous, or watery; itching blotches on various parts of the body. Kreosotum.-Burning sensitiveness and tumefaction of the cervix with bloody ichorous discharge; the genital tract is sensi- tive to touch and to coitus; great putridity of discharges. Belladonna.—Bearing doWN SENSATION as if the INTERNAL ORGANS WOULD ESCAPE EXTERNALLY; pains are of a shooting, tearing character, coming on suddenly and finally leaving as suddenly; hemorrhage profuse and offensive; the parts feel dry and hot internally. China. Especially useful to overcome the effects of the long- continued hemorrhage and leucorrhea; the patient is worse every other day; flatulency, which is not relieved by the discharge of flatus. Lachesis.—Cancer occurring in women approaching or pass- ing through the menopause; frequent hemorrhages; FLUSHES OF HEAT; the pain is sometimes very violent, as if a knife were thrust through the abdomen. Consult:-Phosphorus, rhus tox., sepia, sulphur, murex pur., secale, tarantula, trillium, and zincum met. Curative Treatment.-This has practically resolved itself into one measure, viz., Vaginal hysterectomy. Supra-vaginal amputation of the cervix, as practised by Verneuil, Schroeder and others, still has its advocates; but since vaginal hyster- TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 647 ectomy has become a popular operation, comparatively few surgeons perform supra-vaginal hysterectomy, even though the disease is apparently limited to the cervix. Indeed, vaginal hysterectomy is not essentially more formidable than is the incom- plete operation, and by it both hemostasis and antisepsis are more easily attained. It is utterly impossible to determine, in a given case of cancer of the cervix, whether or not the disease is limited to the cervical portion of the uterus. It is a well-known fact that, in the majority of instances, it is not so limited; conse- quently, the broad principle of extensive ablation which applies to carcinoma of other parts of the body, applies with double force here. It is true that it is not always possible to de- termine, previously to the removal of the uterus, whether or not the disease is limited to this organ. This fact is forced upon us by the return of the disease in a certain per cent. of cases after total extirpation. It must not be forgotten that vaginal hysterectomy is a comparatively recent operation. Un- questionably many uteri have been removed per vaginam that ought to have been left alone. The operation is justifiable under certain conditions only; these conditions should prevail before it is attempted. Indications and Counter-indications for Vaginal Hyster- ectomy.-Vaginal hysterectomy is indicated when the disease implicates the fundus, and the uterus is yet mobile; and when no evidences of its invasion beyond the uterus can be obtained by careful examination. I do not believe that the surgeon is justified in operating if the vagina is even slightly involved at its fornices, if the uterus is fixed, or if large glands can be detected in the folds of the broad ligaments, or extend along the utero-sacral ligaments. A most careful examination should, therefore, always precede the operation. Much information can be obtained by the bi- manual, if embarrassing obstacles do not exist. The cervix should be drawn down with the volsella and an exploration made through the rectum. In case of doubt, a more extended examination should be made under an anesthetic. Operation. The patient should be prepared for the operation as for abdominal section. The bowels, and especially the rectum, should be thoroughly emptied, and the vagina carefully disinfec- 648 A TEXT-BOOK OF GYNECOLOGY. ted. Antisepsis of the vagina is secured by frequent douching with a 1: 3000 bichlorid solution. A preliminary curetting, where the papillomatous masses are abundant, is advisable. Unless this precaution be taken there is danger of infecting the peritoneum with the cancerous discharge during the operation. The curet- ting should be done four or five days before the hysterectomy is performed. After the patient is anesthetized she should be placed before a good side light in the lithotomy posture. The Fritsch specula are preferable to the Sims, the superior blade permitting of continuous irrigation. Lateral retractors (Fig. 145) are also necessary. A final washing of the vagina is resorted to, when the cervix is seized with strong volsella and carried forward. The bladder FIG. 145. G.TIEMANN & CO. SIMONS' RETRACTOR. is located by introducing a sound through the urethra, and sweeping it over the anterior portion of the cervix. An incision is then made with a scalpel through the mucous membrane above the diseased area, completely encircling the cervix. The scalpel is now discarded and further dissection is made with blunt, curved scissors, or with the fingers. The dissection is extended posteriorly toward the Douglas cul-de-sac, which is opened into, and then enlarged with the fingers or with a dilating instrument (Sims's uterine dilator is very useful for this purpose). Two fingers of the left hand are next introduced through the opening thus made and, guided by the posterior layers of one of the broad ligaments, are carried over the liga- ment and into the utero-vesical pouch. The fingers will serve as a TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 649 guide for opening into this pouch, the mucous membrane in front of the cervix having been dissected up as far as the peritoneum. Some difficulty may be experienced in tearing the tense perito- neum with the finger; this may be overcome by using a pair of sharp-pointed dressing-forceps, which are introduced, expanded, and then withdrawn. The tissues are separated laterally as far as the base of the broad ligament on either side. The broad ligaments may be secured either with forceps or with ligatures. Unquestionably, the forceps is the easier and more expeditious way of securing them. Their use, however, is not without certain objections that do not apply to the ligature; there is greater danger of sepsis as well as obstruction of the bowel. Forceps devised especially for the purpose and long enough to include the entire broad ligament in its blades (Fig. 146) may be FIG. 146. ETLEMANN & CO. LEE'S MODIFICATION OF GREIG SMITH'S BROAD LIGAMENT CLAMP. applied, or several smaller ones may be substituted for the special instrument. When the smaller ones are used, it will be neces- sary to apply the first pair to the lower border of the broad liga- ment, incise to a depth corresponding to the blade of the instru- ment, and then apply the second pair above the first, and repeat this procedure until the entire ligament is secured and severed. I have left ten or twelve pair of forceps within the vagina when used in this way. The broad ligament on one side is first dealt with in the manner described, after which the second one can be secured with much less difficulty. After the uterus is cut away the edges of the wound are brought together between the for- ceps on either side with one or two sutures; the peritoneum is included in these sutures. The vagina is again thoroughly 650 A TEXT-BOOK OF GYNECOLOGY. washed with a 1 : 5000 bichlorid solution; iodoform gauze is then loosely packed about the forceps in the vagina. The forceps, which are left behind for from twenty-four to forty-eight hours, afford sufficient drainage, and, as a rule, little or no hemorrhage follows their removal (Péan). When the ligature is used, according to Leopold's method, a special instrument devised for the purpose is necessary (Fig. 147). After the mucous membrane has been dissected from the cervix to the bases of the broad ligaments, the first ligature is introduced about three-quarters of an inch from the lower border of one of the ligaments. In order to avoid the ureters, it should be placed as near the cervix as is possible without including diseased tissue. This ligature will ordinarily secure the uterine artery. After one is placed on either side, the ligament can be incised nearly to its upper border. A second ligature is placed above the first, and the broad ligament again divided for a suffi- FIG. 147. GTIEMANI THE AUTHOR'S NEEDLE FOR VAGINAL HYSTERECTOMY. cient depth. This process is repeated until both ligaments are secured, and the uterus detached and removed. It is, I think, a good plan when the broad ligaments are secured by ligature to introduce at least one or two sutures in such a way as to bring both edges of the wound together at its middle. Some operators recommend stitching the stumps of the broad ligaments in the wound. I can see no special advan- tage in doing this. The question of drainage will be decided by the predilections of the operator. Personally, I think it best when the forceps are not used to secure drainage for at least three or four days. This can be done by introducing a glass tube through the wound and packing about it iodoform gauze; or a strip of iodo- form gauze may be passed into the wound and left behind for from three to six days. I do not deem it wise to leave the TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 651 wound entirely open, as is recommended by some operators. In one of my cases where this was done, the intestines came down into the vagina when the gauze was removed. After the removal of the gauze the vagina should be kept clean by frequent irrigation with a 1:5000 bichlorid solution. Care must be taken that none of the antiseptic fluid passes into the peritoneal cavity. Whether the appendages should be removed with the uterus will depend upon circumstances. If the ovaries and tubes are easily accessible, I think it best to remove them. If, on the other hand, the operation will be made much more difficult by their removal, it is best to leave them behind. Their presence will give rise to but little trouble, even though the patient has not ceased to menstruate. Indeed, it is recommended by one operator (Thornton) that the ovaries be left behind for the pur- pose of preventing premature climacteric changes. The after-treatment does not differ from that recommended for abdominal section. The patient should be kept in bed for at least two weeks, and prevented from undue exertion for some time longer. The same complications liable to arise after lapar- otomy may follow vaginal hysterectomy, and, if they do occur, should be dealt with in the same way. Accidents.-Injury to the ureters is the most frequent acci- dent. This is best prevented by hugging the cervix as closely as possible during the operation. It is announced by the ordinary symptoms of uremia, or by the formation of a uretero-vaginal fistula. The bladder is likewise occasionally injured. If opened into during the operation, it should be closed at once by silk sutures. A still rarer accident is perforation of the rectum. This, however, will not happen unless the operator is exceedingly careless. When death occurs, it may be due to hemorrhage, shock, septicemia, peritonitis, or intestinal obstruction. Death from hemorrhage was very much more frequent before the technique of securing the broad ligaments was fully mastered. Shock may be due either to the loss of blood, or to the difficulties attend- ing the operation. It is much less severe in short operations than in operations requiring a long time for their completion. 652 A TEXT-BOOK OF GYNECOLOGY. The Results of Vaginal Hysterectomy.-In considering the results of vaginal hysterectomy, it is no more than right that the statistics should be based upon the experience of specialists who have performed the operation many times. I can do no better than quote the tables furnished by Pozzi. The first comprises the experience of four German gynecologists up to the end of 1886, and is as follows:- Recurrence at the end Leopold, out • of- I year, 1½ years, of 36 Opera- tions. Schroeder, out of be Opera- tions. 17 Fritsch, out of 53 Martin, out of 56 Operations. Operations. 16 20 35 9 IO 17 32 5 7 7 25 3 years, 2 4 2 20 4 years, 2 • 4 2 25 5 years, 2 4 2 3 6 years, 2 4 2 2 2 years, "These figures give the following percentages: Recurrence at the end of one year, 42.30 per 100; one and a half years, 32.90; two years, 21.15; three years, 13.41; four years 2.40.”* A still more important series is that of Leopold's. Out of eighty vaginal hysterectomies for cancer made by this specialist, only four succumbed to the operation. I again quote from Pozzi† to show the final results of the seventy-six patients that recovered. Out of seventy-six patients re-examined after recovery there remain, without recurrence: 5½ years, 54 years, 44 years, 334 years, 3½ years, • • • .1 3 222 • 6 years, 234 years, 2½ years, 214 years, 2 years, 3 • 3 4+ • Between I year and 2 1½ years, • 3 114 years, 2 2 3 months, • 3 I do not believe that these statistics, notwithstanding the fact that they are based upon the results obtained by some of the most celebrated operators, fairly represent the per cent. of cures possible under more favorable conditions. Undoubtedly, many of the operations included in the figures given were made upon * Pozzi, “A System of Gynecology," p. 237. † Ibid, p. 238. In dealing with a disease inevitably fatal, as is carcinoma of the uterus if un- molested, a radical cure of twenty-five per cent. only of all cases operated upon must be considered successful. TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 653 inoperative cases. It seems to me utterly useless to resort to vaginal hysterectomy after the disease has extended beyond the uterus, implicating the vaginal tissue and the structures within the pelvis. If the cases are properly selected, the results ob- tained are certainly most satisfactory. The average immediate mortality following vaginal hysterectomy should not be greater than ten per cent. ; and, as we have seen by the statistics of Leo- pold, it may be reduced as low as four per cent.* The same objection cannot, therefore, apply to vaginal hysterectomy that applied to the older abdominal operation of Freund, with its frightful mortality of 75 per cent. Modifications of the Operation.-If there is difficulty in securing the broad ligaments, the uterus may be inverted by grasping its fundus through the posterior cul-de-sac with a pair of volsella forceps and drawing it down into the vagina. This will twist the broad ligaments in such a way as to make them much more easily gotten at. It may be necessary to incise the perineum in order to obtain sufficient room to work within the vagina. Martin stitches the peritoneum to the mucous membrane of the vagina, both in front and behind, with interrupted sutures. Fritsch begins his dissection at the lateral fornices and secures the uterine arteries as the first step in the operation. Schatz does not detach the bladder until the last step of the dissection. Olshausen guards against infection of the peritoneum by defer- ring the opening of the cul-de-sac as long as possible. Müller seeks to control the hemorrhage by pressure upon the abdominal aorta. Sanger recommends the thermo-cautery for dividing the vaginal cul-de-sac. Fritsch and Czerny turn the uterus for- ward instead of backward. Montgomery passes a large sponge, to which is attached a tape, into the posterior cul-de-sac as soon as it is opened, so as to keep the intestines back and prevent blood from entering the peritoneal cavity. Otto Zuckerkandl makes a transverse incision, between the ischiatic tuberosities, through the perineum so as to increase the space at the ostium vaginæ. It may be necessary to resort to one or more of these modifications in a given case. (Pozzi.) * Doctors Lee and Pratt, of this country, have now reduced their mortality in vaginal hysterectomy to less than four per cent. 654 A TEXT-BOOK OF GYNECOLOGY. Wolfler and Zuckerkandl practise parasacral and pararectal incision when it is impossible to remove the uterus through the vagina. Kraske extirpates not only the coccyx but the inferior part of the sacrum as well, thus creating a large opening through which the cancerous uterus can be removed. Hegar, instead of removing the coccyx and a portion of the sacrum, depresses them after severing their lateral attachments. The bones are replaced after the hysterectomy is completed. These operations are nec- essary only when the uterus is so large as to make it impossible to remove it through the vagina. It is exactly this condition which, in ninety-nine cases out of a hundred, is associated with in- fection of the periuterine structures—hence any form of hys- terectomy is counter-indicated. I allude to them for the sake of completeness only. Dr. Pratt's new method of performing vaginal hysterectomy is now receiving much and favorable attention. I have seen Dr. Pratt make his operation but once, and that was in a most unfavorable case of cancer of the cervix-a case which seemed to me (I did not make a physical examination) too far advanced for any kind of a radical operation. Those who have seen Dr. Pratt operate in suitable cases describe his technique as being most ingenious. I have the impression, nevertheless, that however well-adapted it may be to hysterectomy for non-malig- nant diseases of the uterus, it is not the best method of remov- ing cancerous uteri. The broad principle of extensive ablation can hardly be observed by hugging the uterus in the process of dissection. I deem it but just to Dr. Pratt to give his own de- scription of the operation, which is as follows: *- The uterus is first dilated and packed with antiseptically-prepared candle-wicking, to render it firm and easily distinguishable from surrounding tissues. The very tip of the cervix is then seized by a small double vulsellum or transfixed by guy ropes, and, while an assistant is drawing the uterus downward to its easy possibilities, the mucous membrane covering the outer surface of the cervix is amputated with a pair of sharp scissors, curved at the tip, as close to the end of the cervix as is practicable, the cut being made completely around the cervix. A spud is then employed to skin the mem- brane of the cervix from below upward as far as the ligamentous fixation of the uterus at the junction of the neck and body. The dissection should progress evenly around the entire circumference of the cervix, as this permits the symmetrical descent of the * Medical Century, November, 1893. TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 655 uterus and brings the entire field of operation easily within view. The ligamentous attachments at the upper end of the cervix are to be completely exposed by a spud, and from this point onward the dissection must be made either with tenaculum and scissors, or with a sickle-knife, such as I have devised for this work. Where the vagina is sufficiently copious the thumb and finger of either hand may displace the tenaculum, and, where these can be employed, are superior to it, as they aid in discriminating the boundary line between the uterus and the surrounding tissues. By cutting all ligamentous attachments close to the surface of the uterus it is possible to avoid the wounding of any large-sized blood-vessels. The dissection is to be carried on evenly around the circumference of the uterus until it reaches in front the point where the peritoneum is reflected from the anterior surface of the uterus upon the posterior sur- face of the bladder, and at the back where the peritoneum is reflected from the poste- rior surface of the uterus upon the anterior surface of the rectum. At these places the peritoneum is to be seized with a tenaculum and snipped with scissors, the open- ings to be enlarged by divulsion, either with a pair of forceps or with the fingers, until the wound extends on either side to the lateral margins of the uterus. The finger can now be introduced into the peritoneal cavity at the posterior opening, and by flexing it the lower part of the broad ligament and its contents can be brought into easy view, the assistant, by traction upon the guy ropes or vulsellum, drawing the uterus, to the opposite side. The dissection can now progress on one side of the uterus by the aid of scissors or the hysterectomy knife, until the uterus descends sufficiently to permit the operator to curve his finger around the upper margin of the broad ligament, after which the dissection can be continued until the attachments of the broad ligament at one side of the uterus are entirely severed. In making this dissection the uterine artery is usually observed pursuing its tortu- ous course upward between the folds of the broad ligament. It bulges into the wound so plainly, and its pulsation can be so easily detected, that it often serves as a land- mark in the dissection, although the only safe rule is to adhere to the proposition that the dissection must constantly hug the uterine tissue, a diversion from this rule to the extent of the sixteenth or even thirty-second part of an inch being often followed by profuse hemorrhage. Before completely severing the broad ligament, it is well to seize one or both of its margins with a pair of T-forceps, so as to place the margins of the peritoneum en- tirely at the command of the operator. With a double vulsellum the side of the uterus which has been liberated by the dissection is now to be seized and dragged downward. The forefinger of the operator is to be placed back of the remaining broad ligament, and the tissues severed either from below upward or above downward, as is most convenient, care being taken as before to secure control of the margins of the broad ligament by T-forceps before the dissection is completed. When the uterus is removed, upon examination it will be readily seen that the anterior and posterior surfaces of the body of the organ are covered by the perito- neum, and that only on the side has the dissection proceeded as far as the fundus. This dissection will have the appearance of a V, with its apex at the fundus and its base at the lower part of the body of the uterus. The uterus itself has not been wounded. Several times I have made this dissection with the loss of not more than one or two teaspoonfuls of blood. In perhaps a majority of the cases (and I have now operated upon forty-seven), it has not been necessary to use an artery forceps during 656 A TEXT-BOOK OF GYNECOLOGY. the entire operation. Quite frequently, however, from not following the rule, and from omitting to hug the uterus closely enough in the dissection, artery forceps will be needed and a ligature called for. In very exceptional cases several ligatures will be required before the completion of the dissection. The loss of blood, however, need never be excessive, as the field of operation is always well-exposed, and at the command of the operator. The T-forceps, which were fastened upon the margins of the broad ligaments, are now to be seized one at a time, and traction employed to bring the ovaries and Fallo- pian tubes into view. This can be done in a majority of cases, when they can easily be removed, and the peritoneal wound thus made can be closed by a continu- ous catgut suture. If, in removing the tubes and ovaries, the dissection be carried close to the organs, it is usually a bloodless procedure. Occasionally, however, adhe- sions will prevent the ovaries from being brought into view, in which case they can be either carefully loosened from their attachments by the finger or a blunt scoop, or may be left unmolested, at the discretion of the operator. In only three cases thus far in my experience have I been unable to remove the ovaries and tubes in this manner. The margin of the wounded peritoneum is now to be seized around its entire cir- cumference by T-forceps and brought well into view. Beginning posteriorly, its edges are to be carefully coaptated by a continuous catgut suture, after which, while the wounded surface of the vagina is held apart by T-forceps, a plug of absorbent cotton wrapped in antiseptically-prepared silk, and sufficiently large to entirely fill the open- ings at the upper extremity of the vagina, is introduced into the wound. The lower part of the vagina is then packed with iodoform gauze, and the operation is complete. Occasionally, where the cervix has been pretty thoroughly destroyed by cancerous degeneration, and where the tissues of the upper part of the cervix have been so rein- forced by inflammatory products as to retain the uterus too high in the pelvis to ren- der the dissection an easy one, after the peritoneal cavity is entered, the fundus of the uterus may be drawn down into the vagina either forward or backward, as is most easily accomplished, and seized by a double vulsellum. This can be accomplished by "climbing” upon its surface with tenacula, employing two or three of them, and inserting them one by one, each a little higher than the other, in the body of the uterus until the fundus is reached and dragged down. As soon as the fundus is made to appear in the vagina it is seized by a double vulsellum, and, while the assistant is using traction upon it, the attachments of the broad ligament to the uterus can be severed from above downward, the same care being exercised to confine the dissection closely to the body of the uterus. Of the forty-seven cases which I have operated upon, nineteen were for cancers, several of them so far advanced in the destructive process as to have rendered removal by means of clamps or ligatures so difficult that I think it would have been impossible for me to have applied these methods, although it would not be modest for me to say that other operators could not. In one case the bladder was involved to such an extent that it ruptured easily in the early part of the operation, the cancerous process having invaded this organ. In another this was true of the rectum. In several the cervix was entirely gone and the operation could not be performed from below upward, and the peritoneum had to be entered and the work accomplished from above downward. Two of the cases were fibroid tumors, weighing two and a half pounds respectively. Several of the cases presented quite a number TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 657 of small extra-uterine fibroids, others several small intramural fibroids, and two or three of them intra-uterine fibroids. Four were for reflex troubles, where the removal of the ovaries some years previously had brought no benefit, but the removal of the uterus was satisfactory. Twenty were cases in which an exploratory entrance into the peritoneal cavity between the uterus and bladder disclosed ovaries and tubes in such a degree of degeneration as to demand removal. Where the ovaries and tubes require removal it seems to me an untimely proceeding to do so and permit the uterus to remain unmolested, as it is now an almost universally accepted theory that ovarian troubles have their beginnings in pathological conditions of the endometrium, and it is my practice where it is necessary to sacrifice the ovaries and tubes, to remove the uterus also. In several of the cases there was pelvic cellulitis, and the dissection opened abscess cavities which bathed the parts freely in pus. In several cases the ovaries were simply large abscesses, and in a few the tubes were enlarged and filled with pus. Four were for procidentia. Of course, there has been no wounding of the ureters, as this method of operating renders this accident entirely uncalled for. Not a single case has developed even the slightest degree of peritonitis. There have been no secondary hemorrhages but one, ending in death. In the forty-first case a uterine artery was accidentally wounded and ligatured with catgut. In all probability the ligature was not well applied, as an hour later, while I was engaged in operating upon another case, during a retching spell the patient experienced an excessive hemorrhage, and before it could be checked this had so depleted the patient that she succumbed the evening of the same day. I am free to confess that this accident should not have happened, and it is with deep regret that I am compelled to chronicle this single break in an otherwise perfect record, in so far as recoveries are concerned. The fatal case was not a difficult one to operate upon, but the patient was hemorrhagic and her arterial coats were degenerated so as to be quite brittle. Perhaps instead of slipping the ligature the artery broke off during the strain upon it when she vomited. Illustrative Cases. I have selected three cases of vaginal hysterectomy from my own case-book, for the purpose of showing the special difficulties and complications liable to arise. The two cases of fistulaæ- rectal and vesical-show their tendency to spontaneous closure. if properly cared for. CASE LXXII.-Diffuse Sarcoma of the Mucous Membrane of the Uterus of Over Two Years' Standing. No Tangible Infiltration of the Broad Ligaments, Bladder, Vagina, or Rectum. Total Extirpation of the Uterus and Left Ovary. Opening into the Rectum. Recovery.* Mrs. L., æt. 52, of Cohoctah, Livingston County, Michigan. She presented herself at my clinic January 5, 1887. Her mother is living, aged sixty-nine years, and has always enjoyed the best of health, having a perfect family history. Her father died twenty-one years ago at the age of sixty, death being caused by some form of ulceration of the leg, which had existed for thirty years and which was supposed to be the sequela of mercurialization. Her father's * Transactions of the Homeopathic Medical Society of the State of Ohio, 1887. 42 658 A TEXT-BOOK OF GYNECOLOGY. sister had a similar sore which, during a period of twenty years, made its appearance at variable intervals. The patient has been married for thirty-four years, having borne six children at term and having had one miscarriage. The oldest child, a son, is thirty-two years of age; the youngest twelve. The miscarriage occurred three years after the birth of the last child. Her labors were always difficult, and at the last confinement the placenta was adhered and had to be forcibly removed. She did not get up well from this labor, and afterwards was troubled with prolapse of the uterus, the cervix at times presenting externally. She began to menstruate at sixteen, and up to the birth of her last child the menses were normal in quantity, quality, and duration. During the last twelve years, however, this function has been painful, the discharge being usually watery or light colored, though at times dark red or green. Two weeks before the miscarriage she suffered from an attack resembling peritonitis and flowed excessively before the fetus was expelled. From this time on menorrhagia and metrorrhagia became prominent symptoms, and her attending physician, attribut- ing the unnatural flow to local congestion, endeavored to check it by scarifying the cervix. This treatment proving ineffectual, he dilated the cervix and explored the uterine cavity with the finger, finding, in the language of the patient, "a mass," which he failed to remove after repeated efforts. Three weeks later medicated uterine injections were resorted to, which temporarily controlled the hemorrhage. In a few weeks the discharge recurred, and with it were pieces varying in length from one to three inches, which (again to use the language of the patient) "resembled chicken-lights." These pieces continued to pass for about six weeks, when they disappeared and did not recur until two years ago. Meanwhile, the floodings recurred at intervals varying from one to three months, and lasted from one to four weeks. These attacks were accompanied with an intense neuralgic-like pain in the abdomen. Two years ago she suffered from an unusually severe attack of this character, which was followed by metrorrhagia, continuing four months. The discharge was thin, watery, unoffensive and not unlike the washings of fresh meat. Since last Septem- ber she has flowed continuously, shreds of membrane at all times being present in the discharge. The patient had, upon entering the hospital, a decidedly cachectic appearence, but the cachexia more closely resembled that of anemia than malignancy. Although weighing one hundred and sixty pounds, her flesh was soft and unnatural. A local examination made on the above date, revealed the following condition : The uterus was enlarged and prolapsed; the cervix was greatly hypertrophied; the os was dilated and gaping; the cervix was badly lacerated and contained much cica- tricial tissue; both vaginal walls had descended with the uterus, causing a cystocele and a rectocele; the perineum had been torn down to the sphincter vaginæ, and the ostium vaginæ was greatly dilated. The uterus was so heavy that I could not, or rather did not dare, reposit it with the sound. With the aid of the volsella, however, the organ could be dragged down- ward far enough to expose the cervix externally, showing that there could be no adhesions of the fundus. I could discover no nodules involving periuterine cellular tissue; nor was there any evidence of involvement of the bladder or rectum. TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 659 Under chloroform a sufficient amount of tissue was removed, with the curette, to make an examination. Macroscopically, this resembled pieces of membrane not altogether unlike scrapings of fresh meat; microscopically, the closely set round cells, with an occasional spindle cell, pointed unmistakably to sarcoma. January 22, 1887, the patient was again brought under the influence of an anes- thetic, and the cervix dilated sufficiently to admit the index finger. The whole endometrium was found to be in a degenerated condition, the uterine cavity being filled with a soft, friable mass springing from it. With Simon's spoon- curette I removed the diseased tissue as thoroughly and completely as possible, afterwards washing the cavity with a two per cent. carbolized solution. Churchill's iodin was then applied to the entire raw surface, a glycerin tampon introduced, and the patient placed in bed. The usual precautions were observed to guard against peritonitis, but the operation was followed by an attack which was more or less diffuse, the temperature reaching 104°. There was at least two ounces of the morbid tissue removed, which was of a grayish-white color, soft and pulpy in consistence. By February 2d the inflammatory symptoms had subsided, though there was a pro- fuse and somewhat offensive discharge of pus from the uterus, the cervix remaining dilated. After thoroughly cleansing the cavity another application of iodin was made, which temporarily improved her condition in every way. At the end of three weeks, however, the unfavorable symptoms returned, when vaginal hysterectomy was decided upon. This was done on March 7, 1887, in the presence of the senior and junior classes of the college, and Dr. J. M. Lee of Rochester, N. Y. Never having before seen or performed the operation, I followed as nearly as possible the description given by Schroeder. After using an antiseptic vaginal injection, and after anesthesia had been induced by the use of whiskey,* the patient was placed in the lithotomy posture before a good light. An effort was first made to drag the uterus down sufficiently with a strong pair of volsella forceps, but the tissues of the cervix were so friable that the instrument would tear its way out. The cervix was, therefore, pierced with a needle properly threaded, which was carried as closely as possible to the utero-vaginal junction. The long ends of the silk in the hands of one assistant gave complete control of the organ, and made it possible to drag the cervix down to the ostium vaginæ. Owing to the displacement of the anterior vaginal wall, a large-sized male sound was introduced into the bladder. Guided by the sound, an incision was made through the mucous membrane of the anterior lip, and with one of Emmet's cervical knives the bladder was dissected from the cervix as far as the peritoneum in front. Next the cul-de-sac of Douglas was opened into with a pair of scissors, and the incisions carried laterally far enough to free the cervix upon the two sides. The index and little fingers of the left hand were next passed over the broad liga- ments from behind and into the utero-vesical pouch. Cutting on these two fingers the peritoneum was divided anteriorly. Seizing the uterus through the posterior opening with a pair of forceps, the organ was retroverted and the fundus dragged into the vagina. The left broad ligament was next transfixed with a quarter-curved Peaslee * I have entirely discarded whiskey as an anesthetic. 660 A TEXT-BOOK OF GYNECOLOGY. perineal needle, which carried with it a heavy piece of braided silk. After withdraw. ing the needle the ligature was cut in the center, and each half of the ligament tied separately. By the aid of a Wilson perineal needle another silk ligature was thrown around the entire ligament and firmly tied. For fear these ligatures might slip, the unnecessary precaution of including the entire mass in the jaws of a strong pair of Spencer Wells ovariotomy forceps was taken. The forceps cut the ligatures and necessitated the application of second ones. With a pair of scissors this ligament was now severed about an inch from the uterus, when its fellow on the opposite side was treated in the same way-an easy task compared with the difficulties in managing the first. The tubes and ligaments showed no evidences of sarcomatous infiltration; the left ovary, however, presented evidences of cystic degeneration, and was accordingly removed. After thoroughly cleansing the pelvic cavity, a cruciform drainage tube was inserted, the stump of each ligament being fixed in the corresponding angle of the vaginal wound by a wire suture. The vagina was packed with antiseptic cotton, and the free end of the drainage tube protected by plugging it with the same material. Two knuckles of small intestine and a portion of the omentum descended after the uterus was retroverted, but by carefully avoiding them they were not injured. The patient was on the table just sixty-five minutes, and was placed in bed with her pulse somewhat softened, but regular and full. It required about four hours for her to regain consciousness. During the first twenty-four hours following the operation the temperature did not rise above 101°. It then fluctuated between this point and normal until the evening of the 12th, when it reached 103°. This rise followed upon the removal of the tube, and I decided to re-open the wound, and, in some way, permanently restore drainage. Accordingly, the patient was anesthetized and I forced my finger through the vault of the vagina into the pelvic cavity. In my effort to break up any existing pus pockets that might have formed, I was not a little surprised to find my finger in contact with a scybalous mass in the rectum, the accumulation of pus having des- troyed the integrity of the intestine. The idea of the opening into the rectum affording complete drainage did not at that time occur to me. An effort was made to heal it over a rectal tube, which measure, owing to the intolerance of the rectum, had to be discarded after twenty-four hours. During the following eight or ten days water injected into the rectum would pass out through the vagina, and a profuse flow of pus was discharged per rectum. Fecal matter not infrequently made its appearance through the vaginal opening, and as enemata were ineffectual in moving the bowels, a full dose of oil was given on the sixteenth day after the operation. A large proportion of the liquid feces following the administration of the oil passed into the vagina, and small quantities of hardened feces continued to pass through the unnatural opening for twelve days longer. With these exceptions the bowels moved regularly and normally after the twenty-eighth day, and at the end of six weeks the fistula was entirely closed. The patient has remained well up to the present date, July, 1893. I believe that this is the first vaginal hysterectomy made by a member of the homeopathic school, as it is also the first recorded case in Michigan, and I report it somewhat at length at this time that the reader may profit by the mistakes made. TREATMENT OF MALIGNANT DISEASES OF THE UTERUS. 661 CASE LXXIII.-Carcinoma of the Body of the Uterus. Operation. Recovery.- Mrs. M., æt. 31, referred to me by Dr. E. F. Chase of Dexter, Michigan; was married at nineteen. She is the mother of three children, the youngest being six years old. For three years preceding the operation she was kept almost exsanguinated by exces. sive uterine hemorrhages and an offensive leucorrhea. Occasionally growths resembling "bloody polypi" would come away. The uterus had been thoroughly curetted five times without benefit. Before coming to the clinic I resorted to the curette under anesthesia for diagnostic purposes. The curettings were submitted to Professor H. Gibbes, Professor of Pathology in the University of Michigan, who found "unmis- takable evidences of malignancy." On November 4, 1890, I performed vaginal hysterectomy, securing the broad ligaments with forceps. Both ovaries and tubes were removed, the right ovary being as large as an orange and cystically degenerated (Fig. 148). The operation lasted but twenty minutes, and at least five minutes of this time were consumed in securing a portion of the left broad ligament, which had slipped from the grasp of a newly fashioned forceps, which, to my regret, I experi- mented with. There was quite a good deal of capillary oozing, and I very foolishly, FIG. 148. CANCER OF THE UTERINE BODY, WITH CYSTIC DEGENERATION OF RIGHT OVARY. (Wood.) as subsequent events proved, crowded iodoform gauze into the vaginal wound for the purpose of controlling it without stitching the surfaces of mucous membrane together. Shock was intense, owing to the prostrated condition of the patient before the opera- tion. After rallying from this she got on splendidly for the first ten days, having scarcely any temperature and but little pain. The forceps and gauze were removed at the end of thirty-six hours. With the removal of the gauze the omentum was drawn into the vagina. This was carefully washed with a 1 : 10,000 bichlorid solution and returned to the abdominal cavity, after which the vagina was again packed with iodoform gauze. No bad results followed this accident, but on the tenth day urine began to escape through the vagina and, three days later, none passed through the urethra. A vaginal exploration revealed a piece of the gauze protruding through the vaginal wound. After this was removed the fistula quickly healed under frequent vaginal injections, and the patient is now (December, 1893) perfectly well. She left the hospital December 2d, just one month from the day of her operation. The iodoform gauze in this case was entirely unnecessary, as the oozing was not alarming. I no longer use it without first partially closing the vaginal wound. The fistula was undoubtedly due to sloughing, caused by the small portion left behind. 662 A TEXT-BOOK OF GYNECOLOGY. CASE LXXIV.—Epithelioma of the Cervix. Operation. Death.—Mrs. W., aet. 32, Kalamazoo, Michigan. Married for some years, but had never had children. History of criminal abortion some years ago. Family history negative. One year ago her physi- cian removed from the cervix two polypi, which were by him supposed to be non-malig- nant in character. No subsequent examination was made until April 6, 1891, at which time there was found springing from the cervix a fungoid mass which pro- jected into the vagina; this was very vascular. She was referred to me, and presented herself at my office for examination on the following day. I found on physical exploration that the fundus could be moved by manipulating the cervix. The vagina was exceedingly small and the perineum rigid. I could not discover that the surrounding structures were implicated. The general health was not yet involved. The case seemed a desperate one, but the patient was anxious to take the chances attending vaginal hysterectomy. After the usual preparation I operated five days following my first and only exami- nation, in Borgess Hospital, Kalamazoo, being assisted by Drs. Denison, Cornell, Ayers, and O'Brien. I anticipated much trouble, but my anticipations were more than realized. It was necessary to carry the incision of the mucous membrane close to the utero-vaginal junction in order to get above the diseased surface. The mucous membrane was separated from the underlying cellular tissue with much difficulty, but finally, with the finger and the handle of the scalpel, a dissection on either side was made as far as the peritoneum. The peritoneum was exceedingly tense and was only perforated by utilizing a sharp pair of dressing forceps. After its introduction it was expanded and withdrawn in order to tear the peritoneum down to the broad ligaments. The most difficult part of the operation was yet to come, viz., securing the broad ligaments. An effort was made to drag the fundus of the uterus into the vagina through either the anterior or the posterior opening, but without avail. The base of the left broad ligament was first seized with a pair of strong forceps and severed. Owing to the size of the vagina it was almost impossible to pass the forceps high enough to seize more than a small portion of tissue at a time, and many instru- ments were, therefore, required. After securing and cutting the lower half of the left broad ligament, the right was dealt with in the same way, when the vagina was so full of forceps as to make further manipulation within it impossible. I therefore incised the perineal body through its raphé down to the sphincter muscle. This enabled me to secure the upper half of the broad ligaments in the same way, after which the uterus was freed and removed, with twelve pair of forceps left within the vagina. The operation lasted two hours and was beset with difficulties that can only be appreci- ated by those who witnessed it, or those who have undertaken a like one under similar circumstances. The patient rallied nicely from the operation and did well up to the end of the third day. Evidences of intestinal obstruction then presented, and she died 24 hours later. The large number of forceps required in this case had, I be- lieve, something to do with the obstruction, although a post- mortem was not permitted. At the time of operating I had never experimented with Leopold's method of ligating the broad ligaments. Its application, I am sure, would have been infinitely less difficult than was forci-pressure. CHAPTER XLIII. CYSTIC AND ALLIED DISEASES OF THE UTERINE APPENDAGES. The cystic and allied diseases of the uterine appendages may be classified as follows:- I. Adenoid ovarian tumors :- 2. Cysts of the broad ligaments and Fallopian tubes :- 3. Solid ovarian tumors :— a) Simple cysts; (b) Multiple cysts; (c) Proliferous cysts; (d) Dermoid cysts; (e) Papillomatous cysts. ((a) Papillomatous cysts; (b) Parovarian cysts; (c) Enlargement of the hydatid of Morgagni ; (d) Hydrops folliculorum; (e) Cysts of the Fallopian tubes, and tubo-ovarian cysts. (a) Fibroma (solid and cystic); (b) Carcinoma (solid and cystic); (c) Sarcoma (solid and cystic); The diagram shown in Fig. 149, copied from Doran, clearly in- dicates the supposed seat of origin of each variety of tumor given in the foregoing classification. The student is advised to study this diagram carefully. He must, however, bear in mind that many points concerning the origin of these benign and malignant growths are as yet unsettled. ADENOID OVARIAN TUMORS. Simple Cysts.-The coats of these cysts during their early formation are membranous, translucent, and, histologically, do not differ in any way from the natural structure of the Graafian follicles. They are supposed to have their origin in a Graafian follicle, either before or after its rupture. The walls are of variable thickness and simply possess a surplus of material, its elements being identical with those of ordinary fibrous tissue. The epithelium lining their inner coat corresponds to that of the 663 12 13 FIG. 149. 11 ya DIAGRAM OF THE STRUCTURES IN AND ADJACENT TO THE BROAD LIGAMENT. (Doran.) 1a. Multilocular cystic tumor developed in parenchyma of ovary. 3. Papillomatous cystic tumor of ovary in (2) tissue of hilum of ovary. 4. Simple broad liga- ment cyst, independent of parovarium (10) and Fallopian tube. 5. A similar cyst in broad ligament above tube, but not connected with it. 6. A similar cyst close to (7) ovarian fimbria of tube. 8. Hydatid of Morgagni-this never ap- pears to form a large cyst. 9. Cyst developed from horizontal tube of parova- rium. 11. Cyst developed from a vertical tube-cysts of this kind form the papillomatous tumors of the broad ligament. 12, 13. Track of obliterated duct of Gärtner; papillomatous cysts are said to be developed along this track. FIG. 150. MULTILOCULAR OVARIAN CYST. (Doran.) 664 OVARIAN TUMORS. 665 tunica propria of the follicle. They are limited in size only by the containing power of the abdomen. There is a hypersecretion of the follicle which gives rise to, or is associated with, hypertrophy of its walls. The walls vary in thickness from an inch or more to the extreme point of tenuity. Just why the Graafian follicles should undergo these remark- able changes we do not know. It is probable that some irrita- tion-chronic congestion or inflammation—is the starting-point of the difficulty; or it may be that the follicles are so deeply seated in the stroma of the ovary that, although the contained ovum is ready for extrusion, it cannot find its way to the surface, the succeeding changes giving rise to hypersecretion of fluid and hypergenesis of the follicle walls. This is simply a theory; yet it is in harmony with the clinical fact that very frequently ovarian tumors are preceded or attended by dysmenorrhea, chlorosis, anemia, etc.-conditions which would tend to interfere with the function of ovulation. Multiple Cysts.-These are formed exactly as are simple cysts, except that two or more Graafian follicles in apposition grow simultaneously (Fig. 149, 1a), one cavity generally predomi- nating. As time goes on the septa separating the several cysts are absorbed or broken down, so that the tumor, while it does not always become converted into a unilocular cyst, is transformed into a cyst containing from two to four or five loculi only. It will thus be seen that a multiple cyst is simply an aggregation of single cysts. Ovarian cysts may occasionally have their origin in the deep areolar tissue of the ovary or among the vessels of the gland, having no connection whatever with the Graafian follicles. The exact modus operandi by which these cysts are produced is not certain. It is probable that there is first a small deposit of fluid in one of the areolar spaces, which is followed by the produc- tion of a limiting capsular membrane. Possibly, as suggested by Edis, "it is allowable to retreat a step further for explanation and fall back upon the easily aroused innate power of evolution of the plastic nuclei as well as of the tissue." Proliferous Cysts.-These are also known as compound, com- ·posite and complex cysts. They have the same origin as those 666 A TEXT-BOOK OF GYNECOLOGY. already given, although they may be located in any part of the body where epithelial structures are found. They are charac- terized by endogenous and exogenous growths-the former springing from the inner surface of the parent cyst, the latter from its outer surface. These cysts vary greatly in fertility. There may be but a single cluster of secondary cells hanging within the cavity of the parent cyst or upon its outer surface; or cysts may grow from all sides of the parent cyst, compressing each other to suicidal repletion. Smaller cysts frequently grow from the outside of the secondary cysts, from which another group may spring. Contents of Simple and Multiple Cysts.—In simple cysts the fluid may be perfectly colorless, hyaline, or of a pale yellow or straw color. It is usually thin and limpid. Its specific grav- ity varies from 1007 to 1018, and the quantity from an ounce to one hundred and fifty pounds. In multilocular cysts all kinds of fluid may be found in the different loculi. In the chief loculus it may be thin, not differ- ing from that found in simple cysts; other loculi may contain a firm, jelly-like, or colloid material; or pus, blood, etc. The con- tents of proliferous, like those of multiple cysts, are variable. Chemically, Eichwald divides the contents into two classes: (1) The mucous series, which consists of mucin, mucus, peptones, colloid material, and the material of colloid globules; (2) the albumin series, which consists of albumin, albumin peptones (fibrin peptone), metalbumin, and paralbumin. Microscopically, the following substances are found: crystals of cholesterin, blood corpuscles, pus cells, compound granular cells, inflammatory globules of Gluge, epithelial cells, globules of fat, and disintegrated blood. The granular cell is the micro- scopical product most unifor.nly present; the others enumerated are not of so constant occurrence. Dermoid, or Cutaneous Piliferous Cysts.-These cysts frequently develop before puberty, and, while occasionally found in combination with other cysts, they are always congenital in origin. Causation.—The generally accepted view of the origin of these growths is that they are due to the displacement of the OVARIAN TUMORS. 667 external blastodermic layer during the formation of the fetus. The epidermis and other structures found in the contents of dermoid cysts are developed from this layer, and if it is included in that portion of the middle layer from which the ovary is FIG. 151. A DERMOID CYST, WHICH CONTAINED HAIR, TEETH, AND FATTY MATTER. Its exterior is covered with long, shaggy adhesions, through which it was supplied with sufficient blood to maintain its nutrition, the pedicle having atrophied. A thick mass of hair will be seen on its inner wall. (Museum R. C. S. Photographed by the Author.) formed, the rudiments of a dermoid cyst are left in the ovary. (Williams.) Formerly it was thought that they were due to the early in- clusion of an imperfectly developed ovum within one perfectly 668 A TEXT-BOOK OF GYNECOLOGY. developed. Still another hypothesis is that they result from the imperfect development of an impregnated ovule. The first theory is hardly tenable; as for the second, it is only necessary to say that dermoid cysts are found in young children, and cannot, therefore, possibly depend upon conception. Pathology. The cyst wall is composed of two distinct layers, an inner and an outer. The former is not unlike the skin in structure, its lining membrane being composed of pavement epi- thelium. Underneath the epithelium is a layer corresponding to the cutis, though the papillæ are irregularly rounded without any regard to parallel rows. The tegumentary appendages- sebaceous and sweat glands, hair follicles, etc.—are contained in a mass of loose areolar and adipose tissue which underlies that corresponding to the cutis. In this layer there is also frequently found laminæ or spiculæ of bone, frequently of an irregular shape, though having the true structure of bone. Rudimentary or per- fectly formed teeth are also found in this layer; or they may project from the stroma of the cyst wall. (Edis.) The fluid is gen- The contents of dermoid cysts are variable. erally of a pultaceous, greasy nature, and is made up of free fat, cholesterin crystals, and cast-off epithelial cells. The solid sub- stances are tufts of hair* (Fig. 151), balls of fat, and teeth, varying from one to one hundred in number. Other sub- stances—bone, brain substance, muscular fibers, and nerves—are occasionally found. These cysts usually contain but one loculus, though they are sometimes compound. Papillomatous Cysts.-When these cysts have their origin in the ovary they start in the tissue of the hilum (Fig. 149, 2). They contain variable quantities of papillomatous or cauliflower growths. Papillomatous growths are occasionally found in common. multilocular ovarian tumors commingled with adenomatous masses. Papillomatous ovarian cysts usually have a short pedicle, or the tumor not infrequently is intraligamentary. * Mundé found in one case a switch of hair which, after being immersed in ether, measured five and a half feet in length and was as thick as the wrist in its entire length. CYSTS OF THE BROAD LIGAMENTS. 669 CYSTS OF THE BROAD LIGAMENTS. Papillomatous Cysts.-These may be either uni- or multi- locular. Their cavities contain the same papillomatous growths as are found within papillomatous cystic tumors of the ovary. Masses of the tissue may invest the uterine appendages (Fig. 152), completely covering the ovarian surface. There is a great ten- dency for these growths to infect the peritoneum. Doran believes that papillomatous growths of the ovary and the broad ligament FIG. 152. PAPILLOMATOUS DISEASE OF THE BROAD LIGAMENTS, COMPLETELY HIDING THE APPENDAGES. These growths may have been enclosed at an early stage in a cyst-wall. (Museum R. C. S. Photographed by the Author.) have their origin from the tubes of the Wolffian body in the hilum and parovarium. Papillomata, wherever found, may be either benign or malig- nant. They consist of hypertrophy of the papillæ either from the interior or exterior of the glandular cyst. During their early formation they are nothing more than warty growths such as may occur from any surface or any part of the body. They are, however, liable at any time to undergo malignant degenera- FIG. 153. AN OVARY WITH THE BROAD LIGAMENT AND FALLOPIAN TUBE. There is a thin-walled parovarian cyst, two inches in diameter, between the layers of the broad ligament. The terminal part of the Fallopian tube is attached over its surface. The anterior layer of the broad ligament is partly dissected off from the cyst. (Museum R. C. S. Photographed by the Author.) FIG. 154. PAROVARIAN CYST. The Fallopian tube, which is much elongated, is seen above. The posterior layer of the broad ligament has been horizontally divided, so as to expose the cyst which appears to be unilocular, and very thin-walled, without any intra cystic growths. The ovary, laid open, lies to the left. (Museum R. C. S. Photographed by the Author.) 670 SOLID TUMORS OF THE OVARY. 671 tion; hence the necessity of early operative interference before the surrounding structures are implicated. Parovarian Cysts.—(Figs. 153 and 154). These cysts are found between the layers of the broad ligament. They are thin- walled and almost invariably unilocular. Their contents consist of a clear watery fluid of low specific gravity which is non-album- inous. They are generally pedunculated, not extending as far as the uterus between the folds of the broad ligament.* Enlargement of the Hydatid of Morgagni.-This small body, shown in Fig. 149, rarely develops into a cyst large enough to call for operative interference. It is here mentioned simply to make the classification of cysts of the ovary and its appendages complete. (Doran.) The other varieties of cyst included in the classification require no extended description at this time. The cysto-fibroma and myxo-adenoma are simply forms of degeneration of solid tumors. Hydrops folliculorum, cysts of the Fallopian tubes, and tubo-ovarian cysts, are dealt with in the chapter devoted to chronic diseases of the appendages. SOLID TUMORS. Fibroid Tumors of the Ovary.-These growths consist chiefly of fibroid tissue resulting from hypertrophy of the stroma of the ovary. They are of exceedingly rare occurrence, and it is probable that fibroid tumors of the uterus involving the ovary have been more than once mistaken for true ovarian fibroma. Occasionally muscular fiber-cells are found here and there throughout the mass. Ovarian fibroid tumors vary in density, and not infrequently contain loculi or cysts, constituting the so- called fibro-cystic ovarian tumors. Sometimes they possess a loose vascular texture and resemble in their appearance malig- nant growths. (Williams.) So long as the tumor does not undergo cystic degeneration it never attains a large size—usually not larger than a fetal head. Fibro-cystic tumors, on the other hand, not infrequently attain a large size, often growing very rapidly. In the event of cystic degeneration, the partition dividing the * "The true parovarian origin of this kind of cyst is questionable.”—Doran. 672 A TEXT-BOOK OF GYNECOLOGY. cysts often consists of a very vascular fibrous mass from which hemorrhages may proceed, filling the cyst cavity with blood. Occasionally they undergo certain degenerative changes, becom- ing calcified, gangrenous, or they may suppurate. The last two changes are usually due either to twisting of the pedicle or to traumatism. Carcinoma.-Carcinoma of the ovary is more frequently met with than is fibroma. It may be either primary or secondary. Any of the forms of cancer attacking other parts of the body may implicate the ovary. The peculiar character of the ovarian tissue, composed as it is of a fibrous stroma with a dense investing membrane, of Graafian follicles, and of intra-follicular epithelium, which is ever growing, especially favors the development of the various forms of cancer. Malignant cystic tumors of the ovary may occur in one of two ways: First, the walls of a benign cystic tumor may undergo cancerous degeneration; second, infiltration and disintegration may take place in the structure of scirrhous and medullary can- cers, as in fibroma, thus forming a cyst. Sarcoma. Sarcomas frequently undergo cystic degeneration, so that they are met with both as solid and cystic tumors. In many instances they grow rapidly and reach a very large size. Histologically, they present the characteristics of sarcoma found in other parts of the body. Formerly the excessive amount of solid material in polycystic tumors was supposed to indicate sarcoma, and undoubtedly cases of benign tumors were many times incorrectly classified as sarcoma. The Pedicle of Ovarian Tumors. The pedicle varies in length and thickness as well as in consistence. It may be long and slender—not larger than the little finger; or it may be broad and thick. It is composed of the Fallopian tube, broad liga- ment, and ovarian ligament and vessels. It is, of course, covered by peritoneum. The blood, the nerve, and the lymphatic supply of the tumor pass through the pedicle. A considerable space may intervene between the broad liga- ment and Fallopian tube and the utero-ovarian ligament, so that the tumor may seem to have two pedicles. Not infrequently the Fallopian tube is much elongated and usually it is thickened. ! CHAPTER XLIV. CYSTIC AND ALLied diseASES OF THE UTERINE APPENDAGES-(Continued.) SYMPTOMS. Ovarian Cysts.-The symptoms of an ovarian cyst will de- pend upon its size and location. When small it may exist for an indefinite length of time without giving rise to trouble. If, however, it remains within the pelvic cavity, the neighboring organs are liable to be impinged upon in such a way as to cause inconvenience. Dysuria is often excited by the tumor pressing upon the bladder. If it falls into the posterior cul-de-sac, there will be more or less irritation of the rectum; and, should it become incarcerated, complete obstruction of the bowel may result. The uterus is pushed forward or backward according to the location of the tumor. The menstrual symptoms also vary greatly. I have already noted the fact that ovarian tumors are frequently preceded or ac- companied by dysmenorrhea. If but one ovary is involved, the menstrual function is not necessarily affected in any way; or, indeed, if but a portion of one ovary is left intact, ovulation may occur as usual, and menstruation is not necessarily painful. Amenorrhea is probably a more frequent symptom than is menorrhagia, though excessive menstruation is sometimes the result of ovarian tumors. The reflex symptoms are often suffi- ciently marked, even with small tumors, to cause suspicions of pregnancy. The stomach may be more or less disturbed, so that there is a tendency to flatulency, which increases the size of the abdomen. The breasts may also undergo reflex changes which adds to the uncertainty of diagnosis. When the cyst increases in size and becomes large it passes into the general abdominal cavity, unless it is held in the pelvis by adhesions. The pressure upon the pelvic organs is now re- 43 673 674 A TEXT-BOOK OF GYNECOLOGY. lieved, and until the tumor becomes sufficiently large to interfere with the abdominal viscera the patient suffers less than when it was confined to the pelvis. As it becomes larger there will be a sensation of fulness because of the pressure upon the stomach and bowels. Respiration is interfered with, giving rise to dysp- nea; the digestion is disordered, and the pressure upon the kidneys, liver, and other organs adds greatly to the patient's discomfort. As time goes on emaciation becomes marked and there appears a peculiar expression to the face which is known as the facies ovariana. Edema of the lower extremities, from pressure, occurs as a late symptom. Gastritis not infrequently supervenes as the case pro- gresses from bad to worse. The patient can no longer digest or assimilate food; nutrition reaches its lowest ebb; and, worn out by the dyspnea and other symptoms resulting from pressure, death ensues. Dermoid Cysts.-These cysts frequently make their presence known at or about the period of puberty when the changes incident to that period cause them to take on active growth. They grow slowly, and usually do not attain a size larger than that of an adult head.* Owing to the thickness of the walls and the nature of the contained fluid, fluctuation is generally very indistinct, and it may be impossible to detect it at all. The osseous contents may be felt projecting through the cyst wall. Dermoid cysts frequently undergo suppuration, especially during preg- nancy and parturition. As a result, adhesions occur oftener than in simple or multiple cysts, and their contents may escape through the bladder, bowel, or abdominal wall. Unfortunately, sponta- neous cures rarely result in this way, and without operative interference suppuration will continue indefinitely. Rupture rarely if ever takes place into the abdominal cavity. Cysts of the Broad Ligament.-Those cysts of the broad ligament which arise from dilatation of the remains of the Wolffian body or vesicles of the tube are always of small size and rarely become larger than an egg. They hang from the sur- * I removed during the spring of 1893 a dermoid cyst which, together with its con- tents, weighed thirty-four pounds. SYMPTOMS OF OVARIAN TUMORS. 675 face of the ligament by a long, slender pedicle, have very thin walls, and are covered by peritoneum. Their contents are of a perfectly innocent character, and they seldom give rise to any trouble. They are rarely detected except upon post-mortem examination, or upon abdominal section for other causes. The so-called parovarian cysts, on the other hand, because of their size, are of greater importance. The parovarium, or organ of Rosenmüller, analogous to the epididymis in the male, is a small body situated between the folds of the broad ligament and between the outer extremity of the ovary and the Fallopian tube. These cysts are formed by a distention of one of the tubes of the parovarium, and, in exceptional instances, may become large enough to fill the abdomen. They occur oftener in young women, grow slowly, and ordinarily do not attain any consider- able size. They are usually single, and the constitutional symp- toms attending their growth are not marked. While in most instances they are pedunculated, yet there is a greater tendency for them to burrow between the folds of the broad ligament than is the case with ovarian cysts. They are distended with a watery, limpid fluid of low specific gravity, seldom exceeding 1005, the fluid containing a trace of albumen, which usually requires both heat and nitric acid to precipitate it. Owing to the thinness of the cyst walls, fluctuation is more dis- tinct than in ovarian cysts. Fibroid Tumors of the Ovary. The symptoms of fibroid tumors of the ovary do not differ essentially from pedunculated subserous fibroid tumors of the uterus. Indeed, in many in- stances it is utterly impossible to differentiate the two conditions. It will not do to rely upon the mobility or fixity of the tumor in differentiating the two, because a subserous uterine fibroid possessing a long pedicle is often quite as mobile as is a fibroid tumor of the ovary. These growths are differentiated from cystic tumors of the ovary by the fact that they are hard and give no evidences of fluctuation. They grow much less slowly than does cancer, and the constitutional symptoms are not usually so profound. However, any of the solid tumors, either benign or malignant, when undergoing cystic degeneration, may increase in size with great rapidity. 676 A TEXT-BOOK OF GYNECOLOGY. Cancer of the Ovary.-Thomas formulates the following symptoms as suggesting malignant involvement of the ovary:- 1. Rapid development of a solid tumor in the ovary; 2. Marked depression of the vital forces and general condition of the patient; 3. The occurrence of edema pedum and spanemia with a small tumor, which are, consequently, dependent upon the general blood state, and not the result of pressure by the tumor; 4. Lancinating and burning pains through the tumor; 5. Cachectic appearance; 6. The occurrence of ascites without evidences of cirrhosis or other hepatic diseases, organic diseases of the kidneys, or of the heart, or chronic peritonitis. Let the reader bear in mind that while the foregoing symptoms suggest malignancy, too much reliance cannot be placed upon them. Indeed, let him ever bear in mind, when dealing with abdominal tumors, that there is nothing so utterly unreliable as subjective phenomena. During the college session of 1890-91 I had this fact most emphatically impressed upon me by the following case :*— CASE LXXV.—The patient, an American, aet. sixty-three, was referred to me by Dr. Mills of Howell, Michigan. The abdomen was large and evidently contained a tumor of some kind. It apparently was cystic, but not monocystic. Until coming to the hospital she worked daily with but little inconvenience. There was no pain, no dis- turbance of digestion, and the appetite was good. On making the first examination, however, two; symptoms-early emaciation, and the quantity of ascitic fluid which seemed to be present-aroused my suspicions of malignancy, and I so announced to the class and to her medical attendant, who was present. Other than these symp- toms, there were absolutely no evidences of malignancy. On April 24th I made an exploratory incision and found the pelvis absolutely filled with the products of malignancy. I carefully closed the wound after removing the ascitic fluid. The patient came very near dying from immediate shock, and was only saved by the most energetic measures. She finally rallied, passed through the night splendidly, and the next morning was feeling unusually well, with bowels and tem- perature normal. At 10 A. M. she began to vomit "typical coffee-grounds matter," and rapidly passed into collapse, dying two hours later. A post-mortem was made four hours after death by Dr. Rogers, assistant patholo- gist of the University. The peritoneum was studded with cancerous nodules, as was also the omentum. The omentum was closely adherent to the tumor. The tumor * North American Journal of Homeopathy, July, 1891. SYMPTOMS OF OVARIAN TUMORS. 677 sprang from the right side, and the pelvis and abdomen were literally packed with tumor, uterus and broad ligament, all of which were implicated in the cancerous process, and from the entire surfaces of which projected malignant nodules (Fig. 155). The intestines were dark, nodular, and matted together. The liver was indurated, and contained one nodule which was undoubtedly cancerous. The gall-bladder was enormously distended and contained nearly a pint of fluid. The stomach was so soft FIG. 155. CANCER OF UTERUS AND ANNEXA. (Wood.) that it could be readily torn with the finger, and was filled with the peculiar dark gru- mous matter similar to that vomited just before death. Notwithstanding the fearful inroads of malignancy, there were no subjective symp- toms, other than those mentioned, suggesting the condition present. It is true that the patient had been under the care of her physician at various intervals for years, but until the tumor made its appearance her symptoms yielded kindly to treatment, and she had never been seriously ill. 678 A TEXT-BOOK OF GYNECOLOGY. COURSE AND TERMINATION. The course and termination of ovarian tumors will depend upon the age of the patient and the nature of the tumor, as well as upon the many contingencies liable to arise. Monocystic tumors of the ovary grow, as has been shown, more slowly than do multiple cysts. Solid fibroid tumors often continue for an indefinite length of time without giving rise to any trouble, and are not necessarily fatal unless they undergo some of the forms of degeneration which have been referred to. On the other hand, malignant tumors grow with great rapidity and speedily terminate life by undermining the patient's health, or by giving rise to serious complications, unless their progress is · interrupted by operative procedures. Proliferous cysts likewise grow with great rapidity, while a dermoid cyst may be carried through life without the patient being aware of its existence; however, suppuration is liable to arise at any time. The slow growth of parovarian tumors has already been noted. These growths do not usually return after tapping; but, owing to the un- certainty of diagnosis, we are not justified in resorting to tapping as a curative procedure. This point will be referred to later on. The contingencies requiring consideration are:- Spontaneous cures, and cures by internal medication; Twisting of the pedicle; Rupture of the cyst; Inflammation of the interior of the cyst; Hemorrhage from the interior or exterior walls of the cyst; Adhesions; Obstruction of the bowel. The spontaneous disappearance of ovarian cysts by absorption alone is extremely doubtful, notwithstanding the fact that instances of the kind have been recorded. Nearly all specialists are agreed that so long as the fluid remains within the cyst absorption is impossible. Should rupture occur, and the con- tained fluid escape into the peritoneal cavity, it is entirely possible for the fluid to be absorbed; or should rupture fortu- nately take place into the bladder, bowel, or Fallopian tube, the contents may escape through one of these channels. Post- OVARIAN TUMORS-CONTINGENCIES. 679 mortem evidence is not wanting to show that a tumor may gradually atrophy from insufficient nourishment by twisting of the pedicle. I am aware of the fact that, especially in homeo- pathic literature, many cases of alleged cures following the administration of the indicated remedy are reported. Some of them are reported by men whose authority as gynecological specialists is fully established. Nevertheless, the possibilities of curing these cases by internal medication are so remote, that the cysts should not be permitted to continue without operative inter- ference until life is jeopardized by their excessive growth. I have so often had come to me, patients, on whom internal medication had been unsuccessfully tried, and who should have been operated upon months before, that it almost leads me to regret that such cures were ever reported. In alleged cures, the uncertainties of diagnosis should always be borne in mind. Twisting of the Pedicle.-This is not an infrequent accident, the axillary rotation of a tumor free from adhesions twisting the pedicle so as to obstruct its circulation. In the New York Medical Journal for May, 1891, Robertson reports five cases of twisting of the pedicle of tumors occurring in the practice of Lawson Tait. Tuholske * also reports two cases of the accident, in one of which the pedicle was twisted one and a half times and in the other two and a half times. In one of Lawson Tait's cases the tumor doubled in size in three days. This, as suggested by Robertson, is due to the fact that the twisted pedicle allows the arterial blood to pass into the tumor long after the venous blood is cut off. Rapid increase in the size of a tumor should cause one to be on the alert for twisted pedicle. In one of Tait's cases the patient was seventy-eight years old. The twist occurred while she was getting into bed, and the tumor rotated on its axis between three and four times. After operating the patient made a good recovery. In another case gangrene set in as the result of strangulation; and in still another the tumor was filled with pus, the twist probably occurring more gradually. In all of the five cases reported, adhesions had formed to the surrounding structures through which the nutrition was almost entirely derived, the circulation of the pedicle being cut off. * St. Louis Courier of Medicine, December, 1890. 680 A TEXT-BOOK OF GYNECOLOGY. The twist may be only partial, so that the circulation is not entirely cut off, and gradual atrophy of the tumor, as observed under the head of spontaneous cures, may come about. Un- fortunately, this termination is of exceedingly rare occurrence. The pedicle, as a result of the twisting, may become entirely separated from its attachment, when the tumor will be found either loose within the abdominal cavity or attached to some of the surrounding viscera by adhesions. Rupture of the Cyst.-Every operator of experience has met with instances where cysts have ruptured and discharged their contents into the peritoneal cavity. The accident is especially liable to occur when the cyst walls are thin and tense, and when the case is complicated by pregnancy. Other causes are: direct violence, concussion, a fall or sudden blow. The symptoms of rupture are those of shock with subsequent peritonitis. The shock is sometimes very great, and, if asso- ciated with hemorrhage, death may ensue at once. The extent of peritonitis excited will depend upon the nature of the fluid, being much more marked when the latter is gelatinous or puri- form. As has already been shown, spontaneous cure may follow the rupture. Oftener, however, if the patient recovers from the shock and peritonitis, the tumor will refill. Inflammation of the Interior of the Cyst.-The same causes which give rise to rupture may give rise to inflammation. When tapping was a more common practice the accident was met with much oftener than it is at the present time. In multilocular cysts the inflammation may be limited to one loculus. When the inflammation is succeeded by suppuration, as frequently occurs, all of the symptoms of septicemia and pyemia may ensue; or the decomposed fluid may find its way through adhesions either into one of the cavities of the body; or externally through the abdominal walls. Dermoid cysts are particularly liable to undergo inflammation and suppuration. Hemorrhage from the Interior or Exterior Walls of the Cyst.-This may result from injury which does not give rise to rupture. It is often associated with papillomatous degenera- tion. The symptoms will depend upon the quantity of hemor- OVARIAN TUMORS TERMINATIONS. 681 rhage and upon the seat of the effusion. If very great all the symptoms of shock will present themselves. If it escapes into the free peritoneal cavity the ordinary symptoms of hematocele follow. Peritonitis is not infrequently excited by the accident. When a large quantity of blood is poured into the cyst cavity, the tumor is suddenly distended; this form of hemorrhage is oftener the result of twisting of the pedicle. Adhesions.-Adhesions are of frequent occurrence. The tumor may attach itself to any of the pelvic or abdominal viscera, or to the abdominal walls. The liver, the stomach, and the diaphragm may thus become attached to the tumor. As a result, the contents of a cyst undergoing degenerative changes may find their way into any of the hollow viscera contained within the pelvis and abdomen, or even through the diaphragm into the lungs and pleural cavities. When adhesions exist, a history of peritonitis can usually be obtained. Obstruction of the Bowel.-This may be due either to di- rect pressure of the tumor, or to inflammatory adhesions follow- ing inflammation and suppuration. Its presence is announced by the usual symptoms attending obstruction. Terminations.-Death may result from- Exhaustion; Asphyxia; Suppuration and pyemia; Peritonitis; Collapse and shock from rupture of cyst; Intestinal obstruction; Uremia; Hemorrhage either into the cyst or into the free peritoneal cavity from the external surface of the cyst; Twisting of the pedicle. Death is usually caused by a combination of two or more of the foregoing causes: The surgeon having in charge a patient with an ovarian tumor should constantly bear in mind the com- plications liable at any time to arise. He should, moreover, if the patient declines to submit to immediate operative interference, hold himself in readiness to open the abdomen, unless positive 682 A TEXT-BOOK OF GYNECOLOGY. counter-indications exist, as soon as dangerous symptoms mani- fest themselves. A high temperature, instead of being a counter- indication, usually calls imperatively for surgical interference ; it is due, in the vast majority of instances, to suppuration. I have seen the temperature drop in a few hours from 105° to normal after removing a suppurating multilocular cyst. Prognosis. While the course of the several forms of ovarian tumors which have been studied is most variable, the tendency in all is toward a fatal termination unless interrupted by surgical art; and while a tumor, in a given case, may exist for years without giving rise to serious trouble, the instances where this is so, are of such exceptional occurrence as to have little influ- ence in determining the probable outcome of the disease. In the vast majority of instances, the end is only a question of time, if the tumor is unmolested. On the other hand, the average mortality of the best ovariotomists is but six per cent.-so that the whole outlook is at once changed by the intervention of art. CHAPTER XLV. CYSTIC AND ALLIED DISEASES OF THE UTERINE APPENDAGES-(Continued). DIAGNOSIS. The existence of an ovarian cyst may be suspected if the abdomen is enlarged by a tumor which has made its appear- ance gradually, and which does not present the ordinary signs of pregnancy; which has grown from below upwards; which is mobile; which is not tender; and which does not affect the general health until the tumor is large enough to interfere with the functions of the abdominal viscera. Subjective symptoms alone, as I have already emphasized, are entirely insufficient for purposes of diagnosis. Nothing short of thorough physical ex- ploration will suffice; and even then the physician will many times be left in doubt until after the abdomen is opened. Ex- tended experience in abdominal surgery begets modesty. In the language of Tait: "Exact abdominal diagnosis is an impossi- bility, and he who asserts to the contrary is either rash or inex- perienced." The uncertainties of diagnosis, instead of making the physician less thorough in his methods of examination, should make him more so. So much is at stake in dealing with abdominal tumors that anything less than thoroughness is criminal. More than once has the abdomen been opened for the purpose of removing an ovarian tumor when no tumor was found; or when, instead of an ovarian tumor, a pregnant uterus was dis- covered. Besides these sources of error, the chastity of virgins is frequently impugned when the cause of the enlargement of the abdomen, instead of being a pregnant uterus, is an ovarian For these reasons, as well as for many more which suggest themselves, the examiner cannot proceed with too great tumor. 683 684 A TEXT-BOOK OF GYNECOLOGY. care when he suspects the existence of a tumor of any kind within the abdomen or the pelvic cavity. In the chapters devoted to physical diagnosis, I have dwelt at length upon the manner of conducting physical examinations. I shall, therefore, at this time touch only upon a few points espe- cially important in examining for abdominal tumors. The examiner should proceed at all times with extreme gentleness. If pain is caused by palpation or by the bimanual, contraction of the abdominal muscles will be excited. When- ever there is any doubt as regards the contents of the abdomen or pelvis an anesthetic should be administered. This is es- pecially true in dealing with nervous and hysterical patients, or with young girls who have never before been subjected to a physical examination. Pain excited by the manipulations of the surgeon does not necessarily indicate disease. Indeed, hard pressure upon any of the structures within the pelvis or the abdomen will give rise to more or less pain. Suffering may also be induced by the care- lessness of the examiner who has not properly cared for his nails, or who is unduly awkward. Again, the examiner should constantly bear in mind the possibilities of pregnancy. Unless he does there is danger, even in the examination of supposed virgins, of unwittingly producing abortion. No matter what the patient's station in life may be, or what her environ- ment, the examiner's only safety will lie in looking upon the girl or woman as a being capable of conception. Too often errors have arisen from the physician's relying implicitly upon the patient's statement regarding the persistence of the catamenia. Finally, the surgeon should not assert the results of his exam- ination with too much positiveness. He may, it is true, be able to make his diagnosis with almost absolute certainty. Unfor- tunately, this is not always the case, and after exhausting every known method and every precaution, he will every now and then open the abdomen only to find himself mistaken. He should, therefore, be careful to explain to the patient and her friends that an element of uncertainty always prevails. This precaution may save him much future embarrassment. DIAGNOSIS OF OVARIAN TUMORS. 685 The chief causes of erroneous diagnosis after examination are enumerated by Doran as follows: I. Preconceived ideas; * 2. Over-confidence in the patient's history; 3. Omission of precautions; 4. Faulty palpation and percussion ; 5. Real difficulties. Preconceived Ideas.-Preconceived ideas are formed usually because the surgeon has had presented to him, either by the patient or by her medical attendant, a history which leads him to suspect ovarian tumor. Upon examination he finds that the abdomen is unquestionably enlarged, but does not take the pre- caution to eliminate the misleading conditions presently to be dealt with. Over-confidence in the Patient's History.-The surgeon must proceed in his physical examination entirely unbiased by the patient's history. This is true in the case of respectable married women as well as in young unmarried women. In the first instance, the patient may consider herself pregnant because she has experienced sensations similar to those experienced during previous pregnancies; or she may not consider herself pregnant because the usual symptoms attending previous preg- nancies are absent. In the case of young single women, the symptoms of pregnancy, if they exist, may be suppressed. The surgeon must, too, bear in mind that pregnancy may occur after amenorrhea has existed for a long time. Omission of Precautions.-A distended bladder may give rise to uncertainty of diagnosis before the catheter is intro- duced; or a loaded rectum or sigmoid flexure may lead one to suspect the existence of a tumor other than fecal, hence the necessity of having both the bowels and the bladder thoroughly emptied before the examination is begun. A still more im- portant precaution is the use of an anesthetic when there is very great tenderness or rigidity of the abdominal walls, or when there is much flatulency. *"Gynecological Operations," p. 172, 1887. 686 A TEXT-BOOK OF GYNECOLOGY. Faulty Palpation and Percussion.—Palpation and percus- sion should be conducted in such a way as to cause the least possible amount of pain. The entire hand or the entire finger should be used instead of the tips of the fingers, for the latter will cause sufficient pain to incite contraction of the recti muscles. The hands should also be warm and the patient placed in a position favorable to the relaxation of the muscles. Real Difficulties.-These comprise excessive thickness of the abdominal walls, excessive tenderness, the simultaneous existence of tumors and pregnancy, rupture of the cyst walls, peritonitis, etc. It is when these various difficulties are met. with that the skill of the examiner is taxed to the utmost. DIFFERENTIATION. I shall follow Doran's* classification in differentiating the various conditions giving rise to abdominal distention. It is as follows:- CLASS I.-A Tumor or Tumors more or less Distinct. 1. A central tumor, distending lower part of abdomen. A. Freely fluctuating. Ovarian cyst, with one cavity greatly predominating over the others; Broad ligament cyst; Encysted dropsy of peritoneum ; Distended bladder; Hydramnios. B. Fluctuating in parts. Ovarian cyst, multilocular; Ovarian cyst with much solid matter; Fibro-cystic uterine tumor; Pregnancy (later stages). C. Solid, no fluctuation. Solid ovarian tumor; Fibroid uterine tumor; Pregnancy (earlier stages). * Op. cit., p. 174. DIAGNOSIS OF OVARIAN TUMORS. 687 2. A tumor distending lower part of abdomen, not central in position. A. Fluctuating. Renal cyst or retro-peritoneal cyst in the neighbor- hood of the kidney; Cyst of omentum or mesentery; Hydrosalpinx (extreme cases); Ovarian cyst (rare); Cyst in abdominal walls; B. Solid. Extra-uterine pregnancy (tumor may be central); Scybala in cecum or sigmoid flexure; Enlarged spleen (extreme cases); 3. Two or more tumors distending lower part of abdomen. Bilateral ovarian tumors (especially small dermoid cysts); Multiple subperitoneal uterine fibroids. Hydatid disease of peritoneum. Class II.-Abdomen Distended; no Distinct Tumor. I. Fluctuation distinct. Ascites (all cases including those where an ovarian or other tumor may exist). 2. No fluctuation. Tympanites and phantom tumor; Obesity; Pendulous abdomen. CLASS. I.-A TUMOR OR TUMORS MORE OR LESS DISTINCT. 1. A Central Tumor, Distending Lower Part of Abdomen. A. Freely Fluctuating. Ovarian Cyst, with one cavity greatly predominating over the others. This will give rise to dulness on percussion in the lower part of the abdomen. It occupies the middle line, or is slightly to one side, and can be located by palpation. The area of dulness does not change. It is movable en masse only or not at all. There is resonance in the flanks unless ascites is 688 A TEXT-BOOK OF GYNECOLOGY. present. The umbilicus remains normal. A vaginal examination will reveal the pelvic origin of the tumor, and the fluctuation wave can often be distinctly felt by the finger in the vagina. A differentiating table is given on page 693. (v. Figs. 156 and 157.) Broad Ligament Cysts.-A parovarian cyst gives rise to the same area of dulness as does an ovarian cyst. Fluctuation is usu- ally more distinct because of the thinner walls. Its more intimate connection with the uterus, as is shown by vaginal examination, together with the history of the case, will suggest its parovarian origin. Papillomatous cysts of the broad ligament are differ- entiated from ovarian cysts with much difficulty. Frequently FIG. 156. FIG. 157. Y AREA OF DULNESS IN OVARIAN CYST. AREA OF DULNESS IN ASCITES. they are closely incorporated with the uterus and are firmly fixed low in the pelvis. Encysted Dropsy of Peritoneum.-The intestines are bound down by adhesions between which and the anterior abdominal wall ascitic fluid accumulates. An effusion of this kind makes its appearance suddenly, preceded, usually, by a history of peritonitis. The abdomen, instead of being prominent, is more or less flat. The area of dulness is un- changeable. Fluctuation is limited. DIAGNOSIS OF OVARIAN TUMORS. 689 origin. Distended Bladder.-Distention from this cause is of recent It is centrally located in the lower abdomen, and, unless the result of paralysis, gives rise to much discom- fort. It hardly seems possible that this condition could be mis- taken for ovarian tumor, yet it has been. In all cases of doubt the catheter should be passed. Hydramnios.-Dropsy of the amnion sometimes complicates pregnancy so that the amniotic fluid may be greatly in excess. This condition, owing to the fact that the uterine walls are usually very thin, and fluctuation more or less distinct, may simulate an ovarian tumor. Ordinarily, a careful examination will reveal the changes incident to pregnancy-softening of the cervix, changes of the breasts, etc. The subjective symptoms of pregnancy are rarely wanting. Hydramnios is frequently due to albuminuria. B. Fluctuating in Parts. Ovarian Cyst, Multilocular.-The symptoms do not differ from those resulting from a unilocular ovarian cyst, except that fluctuation is much less distinct. Ovarian Cyst with much Solid Matter.-May be either benign or malignant. The constitutional symptoms depend upon the character of the growth. It is exceedingly difficult to dif- ferentiate this condition from a fibro-cystic uterine tumor. A solid or semi-solid ovarian tumor is usually more mobile than is a fibro-cystic uterine growth. Fibro-cystic Uterine Tumor.-Is usually of slow growth at first. It seldom occurs before the age of thirty, is com- paratively rare, and usually gives rise to no emaciation. There is menorrhagia more often than amenorrhea. Frequently the lobulated surface of the tumor can be detected. Upon vaginal examination it will be found continuous with the uterus, and sometimes can be moved with it. Not infrequently the uterine cavity is increased in depth. Pregnancy (later stages).—So difficult is it at times to differ- entiate between pregnancy and an ovarian cyst that I deem it wise to add the following table, taken from Peaslee :— 44 690 A TEXT-BOOK OF GYNECOLOGY. Normal Pregnancy Five and a Half Months or More. Enlargement sudden and rapid; symmet- rical, or inclined slightly to right side; Features natural, healthy; Superficial veins of abdomen not en- larged. Edema of ankles not uncom- mon after seven months; Chest not conical; Fluctuation not very distinct, unless much liquor amnii; Menstruation arrested; Vaginal touch detects softening and ap- parent shortening of the cervix, and enlargement of the uterus; Ballottement feels impulse of fetus; Fetal heart-sounds detected; Movements of fetus felt; Enlargement of mammæ; Umbilical areola in first pregnancy; Has developed within six to nine months; Follicles around the nipple equally de- deloped in both mamma; become white on stretching the skin; Exception.—If fetus be dead, of course, the movements and heart-sounds cease. Ovarian Cysts, Second or Third Stage. Enlargement gradual; asymmetrical till in the third stage; Features emaciated, anxious; Veins are enlarged; edema in late stages, from pressure; Chest conical, if very great distention Very distinct, especially in monocysts; Not arrested till third stage has com- menced; No change in these respects; but uterus is displaced, usually behind the cyst; No result. Very rarely is imitated; None; None; Occurs in exceptional cases only; None; Has developed within one to three years; Unequally developed, and remain of the same color as the areola. C. Solid, no Fluctuation. Solid Ovarian Tumor.-This may be either fibroma, car- cinoma, or sarcoma. When malignant, cachexia, ascites, and general symptoms of anasarca, which rarely if ever attend be- nign tumors of the ovary, are prominent. These growths are distinguished with much difficulty from pedunculated fibroid tumors of the uterus, though usually they are more mobile than the latter. There is an entire absence of fluctuation. Fibroid Uterine Tumor.-If sessile, there is an intimate con- nection between the uterus and the tumor, or the tumor is evidently continuous with the uterus. Uterine fibroids are of frequent occurrence, whereas solid ovarian tumors occur but rarely. A uterine fibroid grows slowly, and is usually attended by menorrhagia. There is tenderness in the lower abdomen DIAGNOSIS OF OVARIAN TUMORS. 691 during menstruation. There is no fluctuation, and the uterus moves with the tumor. Pregnancy (earlier stages).-The well-known signs of preg- nancy will of course be looked for. In determining the character of the tumor the examiner will observe that upon bimanual it is, if due to pregnancy, pyriform, symmetrical, and more or less. resilient. The fundus of the uterus moves in harmony with its lower portion. 2. A Tumor Distending Lower Part of Abdomen, not Central in Position. A. Fluctuating. Renal Cyst or Retro-peritoneal Cyst in the Neighbor- hood of the Kidney.-With renal cyst there is usually a history of urinary troubles, with the occurrence every now and then of pus, blood, or albumin in the urine. Nephritic colic, from an impacted calculus, frequently precedes the formation of a renal cyst. Edema of the lower extremities occurs early, and emacia- tion late. The tumor is unilateral, commences in the lumbar region, and grows forward and downward. The intestines lie in front, instead of behind the tumor. There is clearly no connec- tion between the pelvic organs and the tumor. Should aspira- tion be resorted to, the fluid will contain urea, urates, and chlorides. A large renal cyst is of rare occurrence. Cyst of Omentum or Mesentery.—This is of exceedingly rare occurrence. It chiefly occupies the middle line, though seldom exactly median. Fluctuation is usually obscure, but sometimes some degree of mobility is present. It is not con- nected with the pelvis. Hydrosalpinx (extreme cases).-Under this head may also be included hematosalpinx and pyosalpinx. In rare instances any of these conditions may give rise to an enlargement of the Fallopian tube, which causes it to become abdominal. A dis- tended tube is, however, usually confined to the pelvis, and is detected only upon rectal and vaginal exploration. The tumor is evidently closely connected with one side of the uterus. In hydrosalpinx it is usually painless; though when the tube con- 692 A TEXT-BOOK OF GYNECOLOGY. tains pus or blood, pain is often a very prominent symptom. Distention of the tube is ordinarily associated with menstrual irregularities of some kind. Cyst in Abdominal Walls.-This causes prominent bulging of the parietes. It is rounded and is intimately attached to the abdominal walls, following closely their movements. It gives rise to dulness over the palpable area. B. Solid. Extra-uterine Pregnancy (tumor may be central).—An extra- uterine pregnancy cyst may become solid after the death of the fetus. The fluids are then absorbed and the tumor appears as a hard, irregularly rounded mass, fixed in some part of the lower abdomen or pelvis. It is intimately connected with the uterus, which is always enlarged. The history should be carefully in- quired into, for the symptoms elicited by physical examination may closely resemble uterine myoma. Scybala in Cecum or Sigmoid Flexure.-Fecal tumors are seldom large enough to be mistaken for ovarian cysts. They may occur in any part of the large intestine, and are usually pre- ceded by a history of constipation alternating with colic and diarrhea. They give rise, upon manipulation, to a peculiar doughy feel, and ordinarily can be indented by pressure. As a final test an effort should be made to thoroughly empty the bowels. A Enlarged Spleen (extreme cases).-The conditions giving rise to enlargement of the spleen sufficient to simulate ovarian tumor are leucocythemia, cancer, syphilis, and amyloid degeneration. Occasionally the enlargement may be great enough to extend into the pelvis. It appears first under the left false ribs and extends. downward and inward toward the middle line. The enlarged organ, from its close contact with the parietes, gives rise on per- cussion to absolute dulness over its entire surface. Sometimes the characteristic notched border can be felt. Smaller splenic tumors are slightly mobile. The constitutional symptoms attend- ing the several affections responsible for the enlargement are rarely absent. DIAGNOSIS OF OVARIAN TUMORS. 693 3. Two or more Tumors Distending Lower Part of Ab- domen. Bilateral Ovarian Tumors (especially small dermoid cysts).— A sulcus may be felt between them. In most instances, how- ever, one tumor so completely overshadows the other that the existence of the smaller one is not suspected until after the abdomen is opened. Hydatid Disease of Peritoneum.-Hydatid growths spring- ing from the peritoneal surface, or, more frequently, from the liver, often reach enormous proportions, and by distending the abdomen may simulate an ovarian cyst. A vaginal examination will show that the growth does not have its origin in the pelvis. Percussion will locate the area of dulness high up; fluctuation is more obscure and circumscribed than in ovarian cysts, and frequently the so-called hydatid fre- mitus can be felt. The tumor grows very rapidly from above downward. If the diagnosis is doubtful a fine aspirating needle may be introduced and the obtained fluid examined. As a rule it is perfectly colorless, transparent, of low specific gravity (1007 to 1009), and alkaline or neutral in reaction, though occasionally it may be acid. There are no organic substances. Microscopical examination will reveal the characteristic hooklets. CLASS II.-ABDOMEN DISTENDED-NO DISTINCT TUMOR. 1. Fluctuation Distinct. Ascites.-The following table, taken from Peaslee, cannot be improved upon in differentiating between ascites and large ovarian cysts :- Ascites. Previous ill-health; Enlargement comparatively sudden; Face full, puffy, leaden; Patient on back-enlargement is sym- metrical, flat in front; Patient on the side-flatness on sides; Patient sitting up-abdomen bulges be- low; Large Ovarian Cyst. Good health previously; Enlargement gradual; Face emaciated, peculiar; Enlargement is not usually symmetrical, never till third stage; prominent in front; No change of flatness; Little, if any, change of abdomen; 694 A TEXT-BOOK OF GYNECOLOGY. Ascites (Continued). Skin of abdomen, smooth, tense, shining; On superficial view, abdomen very much enlarged. Edema of extremities in all cases, and, at last, of abdomen also; Floating ribs not bulging; Navel prominent and thinned; More distinct in erect position; Percussion gives a clear tympanitic sound at highest portions of abdominal cavity, in all positions. Is dull elsewhere, and changes with the position; (v. Fig. 157.) Aortic pulsation not felt through abdo- minal walls; Vaginal and rectal touch detect fluctua- tion at once; Uterus normal in size, mobility, and posi tion; sometimes prolapsed; Fluid a light straw-color; coagulates spontaneously; contains albumin and ameboid corpuscles; Anemia supervenes early; Hydragogues and diuretics produce tem- porary relief; Exceptions. If there be a very large ac- cumulation, may be dulness at high- est point of abdominal cavity-patient being on the back; or the intestines may be glued down; but deep per- cussion may elicit tympanitic sounds; one or both flanks may be clear, from gas in the colon. Large Ovarian Cyst (Continued). Abdominal integuments natural, or merely thinned; Superficial view less enlarged. Edema only in exceptional cases; Chest conical from bulging of the false ribs; Navel not thinned; More distinct in recumbent position; Clear sound only at parts not correspond- ing to the cyst, and in both flanks; dulness over it in all positions; (v. Fig. 156.) Pulsations are transmitted through the cyst to the abdominal walls; Fluctuation less clear, and may not be reached at all, or does not exist in case of polycyst; Uterus displaced behind the cyst, gen- erally; Fluid a darker shade; of various hues in polycysts; abounds in albumin or colloid matter; no ameboid corpus- cles; never coagulates spontaneously; Comes on late; These remedies, as a rule, produce no effect; Exceptions. May be tympanitic sound in cyst, if it communicate with intes- tine; one or both flanks may be dull from feces in the colon. 2. No Fluctuation. Tympanites and Phantom Tumor.-It is this condition which is responsible for so-called pseudocyesis, or spurious pregnancy. The patient is usually hysterical and the condi- tion is more apt to occur as she approaches the climacteric period. The abdomen may be distended to the size of a preg- nant uterus at full term, so that the existence of either pregnancy or of a tumor of some kind is suspected. Frequently there is DIAGNOSIS OF OVARIAN TUMORS. 695 an arching of the back which causes the recti muscles to become tense, and which adds greatly to the confusion. The examiner will observe that there is no fluctuation, nor do the evidences of a solid tumor exist. If he can divert the patient's attention by conversation or otherwise, relaxation of the recti muscles will frequently take place, and the actual con- dition be determined; or, if the patient be placed under the influence of an anesthetic, the swelling will quickly and entirely disappear, and the resulting flaccidity of the abdomen will per- mit a thorough examination of its contents to be made. When the patient believes the enlargement to be due to preg- nancy her suspicions are based, not only upon the tympanitic enlargement of the abdomen, but also upon the suppression of the catamenia, which in the vast majority of instances is due to physiological changes incident to the menopause. Usually the patient is exceedingly anxious to become a mother, and the mental condition is such as to cause her to exaggerate every sign suggesting the possibility of pregnancy. The examiner will also observe that the mammary glands are not altered and that the uterus does not undergo the usual changes of preg- nancy, the bimanual showing it to be of normal size and perfectly mobile. Obesity.-Obesity sufficient to give rise to abdominal en- largement simulating an ovarian tumor occurs oftener at or about the menopause. When associated with tympanitic dis- tention the condition may greatly confuse the inexperienced examiner. It will be noted, on exploration, that the enlargement is symmetrical. When the patient assumes the sitting or upright posture the abdominal walls are thrown into pendulous folds, the umbilicus remaining normally depressed. They can be grasped between the two hands, when its great thickness will be indicated. The sensation elicited by palpation is that of a doughy enlargement which yields on firm pressure. The obesity is general, involving the entire body—the face, limbs, breasts, etc. Percussion will indicate resonance instead of dulness. It should be remembered that deep percussing is necessary when the abdominal walls are unusually thick. 696 A TEXT-BOOK OF GYNECOLOGY. Pendulous Abdomen.-Sometimes the abdomen becomes so pendulous as to extend half way to the knees. The walls can be grasped and pinched between the two hands, and there will be an entire absence of all signs indicating either a tumor, ascites, or pregnancy. It will now be necessary, in order to make this chapter com- plete, briefly to consider certain other conditions, with the diag- nosis of which the abdominal surgeon should be perfectly familiar, although they are not included in the schema studied. Cancer of the Pylorus.-A tumor resulting from cancer of the pylorus is small, hard, and movable, and is situated in the epigastrium a little to the right of the median line. In its later stages it becomes fixed. Pressure gives pain. The gastric symptoms are always prominent. Fibroid Thickening of the Pylorus.-This is felt as a local- ized induration in the same location as the preceding condition. It rarely reaches the dimensions of a tumor. It is extremely difficult to differentiate this affection, during its early stages, from cancer. Pressure upon fibroid thickening ordinarily causes much less pain than is the case with cancer. Morbid Growths of the Stomach.-These are, in at least ninety per cent. of all cases, malignant—scirrhous cancer being the form oftener attacking the stomach. If located on its poste- rior surface, which is rarely the case, it may drag the stomach downward as far as the umbilicus. Palpation causes pain. The enlarged viscus is usually movable, at least not becoming fixed until the later stages of the disease. The constitutional symptoms are marked. Molar Pregnancy.-The ordinary signs of pregnancy usually exist, except that the abdominal tumor increases much more rapidly than is the case in normal gestation, and the uterus grows to a greater size. The enlargement will be recognized as uterine, and sooner or later the characteristic discharge (p. 73) will make its appearance. Solid Growths of the Kidney.-These are carcinoma, ade- noma, and the several varieties of sarcoma. Any one of these conditions may give rise to an enlargement sufficiently great to fill the whole abdominal cavity. They will be recognized by the DIAGNOSIS OF OVARIAN TUMORS. 697 dulness produced on percussion over the lumbar region, which ex- tends forward, by their fixity in the region of the kidney, and by the urinary changes which are usually present. Solid Growths of the Liver.-Usually cancerous or sarco- matous. The tumor is oftener located in the right lobe. It will be recognized as a solid resisting enlargement protruding from under the ribs of the right side. Unless adhesions exist, the liver will move upward and downward during respiration. In cancer the characteristic knobs on the surface of the liver can often be felt. The various malignant growths springing from this organ are limited in size only by the capacity of the abdomen. Solid Tumors of the Gall-bladder.-Clinically, a gall-blad- der distended with gall-stones, with thickened walls the result of inflammation, is a solid tumor. The various malignant lesions of the liver may also implicate the gall-bladder. The enlarge- ment is located at the edge of the liver, and extends downward and inward toward the umbilicus. The natural globular, ovoid, or pear-shape of the gall-bladder is usually preserved. There is more or less mobility in lateral directions. Absolute dulness over the enlarged area rarely occurs. Tumors of the Colon.-These growths are either adenoma, adeno-sarcoma, or cancer. The adenomata are usually poly- poidal in shape. In the vast majority of instances they are found in the descending colon, are freely movable for some inches in all directions, and seldom attain a size larger than that of an orange. Cancer locates itself in any part of the large bowel, and gives rise to an indefinable thickening, fixed or slightly movable. When any of these growths are located in the sig- moid flexure, it is possible to detect them by rectal exploration. The intestinal excreta will often indicate the nature of the growth. Solid Growths of the Omentum.-Any of the forms of malignant disease-colloid cancer being the most frequent-may involve the omentum. Such growths give rise to a very irregu- lar surface and are either hard, or boggy, depending upon the proportion of colloid material present. Not infrequently 698 A TEXT-BOOK OF GYNECOLOGY. ascites exists with the disease. It is sometimes possible to determine by palpation and deep percussion whether the growth overlies the intestines. Hematometra.-The tumor is clearly of uterine origin. It is the result of retention of menstrual blood, caused by some obstruction to its exit, located either at the cervix or in the vagina. The menstrual blood does not make its appearance externally, although all of the symptoms of puberty are present. The symptoms of menstruation, minus the flow, recur at regular intervals. The only symptom of pregnancy that exists is en- largement of the uterus. The history, together with a physical examination, will clear up the diagnosis. Hydrometra. Occasionally an obstruction will occur in the cervical canal after the menopause which gives rise to an accumulation of watery fluid within the uterus great enough to suggest an ovarian cyst. The uterine walls are sufficiently attenuated to permit of fluctuation. The accumulation occurs gradually. On physical examination the sound will locate the obstruction and determine the cause of the enlargement. Ovarian Abscess.-Ovarian abscess is usually located in the recto-uterine pouch, on one or the other side, where it is adhered. The tumor is rarely larger than a hen's egg, is obscurely fluctu- ating, and very tender. Distention of the Gall-bladder with Fluid.-The tumor is fixed under the liver, is painless or slightly painful, and is pyri- form or ovoid in shape. It may contain either bile, pus, or water. Nephric and Peri-nephric Abscess. It is not always pos- sible to determine whether an accumulation of pus in the region of the kidney has its origin in the organ itself or in its sur- rounding structures. Indeed, the two conditions are usually asso- ciated. If the suppurating process has continued for some time there may be discoloration of the skin overlying the kidney, with tenderness on pressure. The evidences of fluctuation are not always present. In case of doubt, aspiration can be re- sorted to. DIAGNOSIS OF OVARIAN TUMORS. 699 DIAGNOSIS OF SMALL OVARIAN TUMORS. Ovarian tumors in their early stages may be confounded with- Retroversion or retroflexion of a gravid uterus; Small fibroid tumors of the uterus; Pelvic hematocele ; Pelvic cellulitis ; Accumulation of feces in the rectum; Tubal or extra-uterine pregnancy. Retroversion or Retroflexion of a Gravid Uterus.-The ordinary symptoms of pregnancy are rarely wanting. On physi- cal examination the cervix will be found high up, and there will be felt in the posterior fornix a softish, solid tumor, which is continuous with the cervix uteri. Unless the fundus is adhered it can be pushed out of the hollow of the sacrum by placing the patient in the genu-pectoral posture, drawing the cervix down with a volsella, and exerting pressure upon the fundus either through the posterior fornix or the rectum. Small Fibroid Tumors of the Uterus.-The ordinary signs of pregnancy will be wanting. Upon bimanual the tumor will be found intimately connected with the uterus, moving with it. Menorrhagia is more frequent than amenorrhea. Usually it is possible to palpate both ovaries, and thus determine their nor- mal condition. Pelvic Hematocele.-There will be a history of the sudden formation of a tumor, with the usual symptoms of shock and collapse attending hematocele. The tumor is oftener located in the folds of the broad ligament, though it may be in the poste- rior cul-de-sac. It is suddenly formed, and unless resolution is interrupted by suppuration, gradually diminishes. Pelvic celluli- Pelvic Cellulitis.-There will be a history of inflammation, followed by the gradual formation of the tumor. tis frequently involves the ovary. Accumulation of Feces in the Rectum.—The characteristic pitting upon pressure will be detected. In all cases of doubt the rectum should be flushed with a large enema. Tubal or Extra-uterine Pregnancy.-The symptoms of pregnancy may be present. An elastic tumor will be detected 700 A TEXT-BOOK OF GYNECOLOGY. in the region of one or the other Fallopian tube, present- ing an obscure sensation of fluctuation. The uterus is enlarged somewhat, frequently displaced, and the cervix is softened. There is often a history of paroxysms of crampy, colicky pains in the region of the tumor. Irregular hemorrhages from the uterus are not infrequent. The decidua is usually expelled during an attack of hemorrhage. TAPPING FOR DIAGNOSIS. The only circumstances under which tapping for diagnosis is now justifiable is the existence of some intercurrent disease- bronchitis, pneumonia, pleurisy, etc.—which is sufficiently severe to counter-indicate ovariotomy, and which is made worse by the pressure caused by the tumor; or the existence of great ascites with a small tumor, when the presence of the tumor is doubtful. It is, indeed, questionable if, in the latter condition, exploratory incision in the hands of an experienced operator is not prefer- able to tapping. Those who maintain the advantages of tapping for the pur- pose of diagnosis claim that it can do no harm, and that it is a perfectly safe operation; that much information can be obtained by an examination of the fluid; and that, should the cyst be parovarian, the tapping will result in a cure, making laparotomy unnecessary. That tapping is a perfectly harmless operation is not in keep- ing with the records of the past. Should the trocar penetrate a solid fibroid tumor, or a malignant growth, fatal hemorrhage may ensue. Inflammation and suppuration have more than once followed tapping and aspiration. There is also danger of injur- ing the intestines, it not always being possible to determine their presence or absence between the tumor and the abdominal parietes. It is true that the fluid can be examined, and by it some idea of the nature of the cyst determined. Unfortunately, however, the character of the fluid obtained affords by no means positive information as to the character of the tumor. In the first place, the fluid may be of such a nature as not to pass through the trocar or aspirating needle. Again, in multilocular cysts, the fluid, as we DIAGNOSIS OF OVARIAN TUMORS. 701 have seen, is often very different in different loculi. Nor is the fluid of any form of tumor sufficiently characteristic to afford pathognomonic evidence of its nature. For instance, it is ex- ceedingly difficult at times to distinguish the fluid obtained from a parovarian cyst from that obtained from a simple unilocular ovarian cyst. Finally, parovarian cysts are by no means always cured by drawing off the fluid. It must be remembered, too, that in most instances parovarian cysts are removed by ab- dominal section with but little difficulty. Method of Tapping.—Since this operation will occasionally be called for, I will briefly describe the proper method of its execution. The trocar or aspirating needle should be absolutely clean. If the quantity of fluid is very great, I think the trocar is prefer- able to the aspirator. The bowels and bladder should be emptied, and the patient placed at the edge of the bed upon her side. The site of the puncture is thoroughly washed with a 1:1000 bichlorid solution. Four or five drops of a four per cent. solu- tion of cocain are injected into the site of the incision, midway between the umbilicus and the pubes, in the median line. This site is the preferable one, unless previous percussion has determined the existence of intestine underneath it. General anesthesia is rarely called for unless the patient is extremely nervous. A small incision is made through the skin with a sharp scalpel. A rubber tube two or three feet in length should be attached to the tap- ping trocar, the distal end being immersed in a pan of antiseptic water, so as to prevent the entrance of air into the cyst cavity. The trocar is then thrust into the tumor and the fluid permitted to escape. Previously to passing the trocar a many-tailed binder is placed about the abdomen, and as the fluid is drawn off this should be tightened. After the instrument is removed, iodoform is sprinkled over the site of the incision, and a small pad of antiseptic gauze applied, held in place by a strip of adhesive plaster. The patient should be kept in bed for at least three or four days. In the event of alarming reactionary symptoms the abdomen should be opened at once. CHAPTER XLVI. OVARIOTOMY. The General Principles of Abdominal Section.-In the present chapter I shall consider the general principles of ab- dominal surgery as applied to the various gynecological opera- tions calling for abdominal section. This will save needless repetition in dealing with those affections requiring removal of the appendages for other causes, and removal of the uterus wholly or in part. The abdominal surgeon is compelled to work under many difficulties which do not exist in ordinary operations. His manipulations are necessarily restricted, and he has to do with organs which, though not in themselves essential to life, are in close proximity to those which are. In many instances manipu- lations within the abdominal cavity have to be done largely by the sense of touch. It is rarely, if ever, possible to determine positively the condition of the abdomen and its contents pre- viously to an exploratory incision; and even after the abdomen is opened the confusion is often very great. Again, no two cases calling for abdominal exploration present exactly the same con- ditions. It is, therefore, impossible to give set rules to govern the operator in all cases. Only general principles can be dealt with. Were one to dwell upon all the details covering the many modifications which have been made in the past, an entire volume would be required. The abdominal surgeon must, first of all, be competent to contend with any contingency which may arise from the tying of an artery deep in the pelvis to an intestinal resection, or the removal of a kidney. He must, in addition, possess tact, ingenuity, and coolness. These several qualities are begotten only by extended study, observation, and experience. To obtain them a perfect familiarity with the ana- tomy of the abdomen is the first requisite; the second is an equal familiarity with the various pathological changes liable 702 OVARIOTOMY. 703 to distort any of the pelvic or abdominal organs; and the third and last, is a thorough knowledge of certain surgical principles which are as broad as is surgery itself. In the chapter devoted to antisepsis, I have dwelt in detail upon the necessary preparation of the patient previously to ab- dominal section. The reader, if he is a believer in antisepsis or asepsis, is advised to study this chapter carefully. The prin- ciples therein dealt with, must be observed before the patient is placed upon the operating table. Unless the proper preparation has been made, antisepsis, no matter how carefully carried out after the operation is begun, will fail in its object. When should Ovariotomy be Performed?-With few ex- ceptions the proper time for ovariotomy is as soon as the diag- nosis is made. Ordinarily there is nothing gained by delay. An ovarian tumor will, in ninety-nine cases out of a hundred, run an inevitably fatal course, unless its progress is interrupted by sur- gical interference. It is true that, when the tumor is small and still confined to the pelvis, it may continue indefinitely without serious trouble resulting from its presence. The various contingencies which have been studied-inflammation, suppuration, adhesions, etc.—are, nevertheless, liable at any time to arise. This is specially true of dermoid cysts. A woman is, therefore, never safe while she is carrying an ovarian tumor, and it is best to remove it as soon after its discovery as is expedient. It is not advisable to operate during menstruation if it can be avoided. Formerly, the near approach of this function was con- sidered an imperative counter-indication to immediate operative interference. While it is probably best to set a day for the opera- tion which anticipates menstruation for at least three or four days, or which will correspond to the same length of time fol- lowing its cessation, the observation of this precaution is now looked upon as of much less importance than formerly. More than once I have operated at the beginning of the flow, the ex- citement incident to the operation bringing it on prematurely, and I have never yet had cause to regret so doing. Formerly, it was also considered unjustifiable to operate dur- ing pregnancy. Pregnancy is, however, no longer a counter-in- 704 A TEXT-BOOK OF GYNECOLOGY. dication to ovariotomy. On the contrary, early pregnancy com- plicating a growing ovarian tumor makes ovariotomy all the more imperative. The mortality attending the operation is not greatly increased by the existence of pregnancy; nor does the operation cause abortion even in the majority of instances. As regards the mortality, Olshausen furnishes the following data: * Up to the end of 1885 Schroeder had performed ovariotomy dur- ing pregnancy in twelve cases, Tait in six, Sir Spencer Wells in ten, and Olshausen himself in eight. But one patient of the total of thirty-six died. All authorities are agreed that it is best, if possible, to operate previously to the fourth month. After this time the greater turgidity of the pedicle, as well as of all the pelvic organs, makes the operation more difficult. The age of the patient is no bar to ovariotomy. The operation has been successfully performed by Küster on a child eighteen months old; it has more than once been successfully performed on children six, seven, and eight years old. Young girls from fifteen to twenty years of age are usually good subjects for the operation. As regards the other extreme, Bantock, Janvrin, Schroeder, Miner and others, have made successful ovariotomies upon. women from sixty-five to eighty-one years of age. Of course great decrepitude, or the existence of organic disease, would make the operation, in extreme old age, unjustifiable. There is always a tendency for elderly patients to contract bronchitis from undue exposure, or to suffer from hypostatic congestion of the lungs. (Doran.) Operating Table.-Any ordinary table of sufficient height and narrowness will answer for this purpose. Its height should depend upon the height of the operator-varying from three feet to three feet eight inches. There is nothing more trying to a tall surgeon than to work for a long time over an operating table which is too low. A common, narrow kitchen-table, if sufficiently strong, will answer very well. If not long enough, one of corresponding height can be placed crosswise at its head. * Doran "Gynecological Operations," p. 184, 1887. OVARIOTOMY. 705 The table should be properly protected by clean quilts and a sheet, over which is placed a mackintosh. Clothing. The patient should be properly prepared for the operation by being wrapped in warm blankets. It is sometimes advisable, especially with feeble women, to protect the chest by placing under the flannel jacket a layer of cotton-wool. Preliminary Details.-After being placed upon the table and the clothing properly arranged, the abdomen is exposed by re- moving the antiseptic pad. A final scrubbing is given the abdo- men with a 1 : 1000 bichlorid solution. The pubes is shaved, if this has not been previously attended to, the parts are dried with a sterilized towel, and the mackintosh sheet applied. This is prepared by making an oval opening about seven inches long by six broad, around the inner edges of which is spread adhe- sive material. If the opening is of suitable size, it will fit closely to the abdomen, leaving an exposed area extending from the pubes to the umbilicus, six inches in width at its widest point. The mackintosh will protect the clothing and leave the patient perfectly dry and clean after the operation is concluded. Over the mackintosh, as well as above, below, and at its sides, are spread sterilized towels wrung from a I: 3000 bichlorid solu- tion, so that all instruments used during the operation will come in contact only with these towels. Temperature of the Room.-Formerly, it was thought neces- sary to operate in a room whose temperature was not less than 80°. This is sufficiently great to prostrate both the operator and the patient. While it is not wise to operate in a temperature under 60°, that of 70° is quite warm enough. The bodily tem- perature of the patient can be maintained by proper clothing, and the cooling of the peritoneum and abdominal contents can be prevented by the application of soft, warm sponges and cloths. Arrangement of Instruments.-After the instruments have been properly cleaned, they should be arranged in suitable trays placed conveniently near the operator. It is best to have the cutting instruments in one tray, and the blunt instruments, to- gether with the hemostatic forceps, in another. The following instruments and appliances will be required:- 45 706 A TEXT-BOOK OF GYNECOLOGY. Three trays for instruments and two bowls for sponges; Twenty small pressure forceps; Six large pressure forceps; Scissors bent on the flat; Two stout scalpels; Cleveland's ligature forceps; Cyst or large pressure forceps, straight and elbowed; Pedicle needle; Long free needle with large eye; Ovariotomy trocar and canula with tube; Four sponge holders; Six trocar-pointed needles threaded with No. 2 Chinese twisted silk; Twelve sponges (two or three of which are large flat); Six glass drainage tubes of assorted sizes; A piece of rubber dam, ten inches square, for drainage tube; Dressings, including antiseptic cotton, adhesive plaster, and a many-tailed binder; A director for dividing the peritoneum. In addition to the foregoing there should be conveniently at hand an aspirator, a Paquelin cautery, a serre-nœud (Bantock's modification of Koberle's), with pliers for fixing the wire, and two Wilcox pedicle pins. The Paquelin cautery is a great convenience; the serre-nœud and transfixing pins are to be in readiness in case it is necessary to deal with a fibroid tumor or with a solid ovarian tumor inti- mately attached to the uterus. It is also well to be provided with an elastic ligature sufficiently long to throw about the base of the tumor, should the operation end in hysterectomy. I have excluded from this list the wristlets and thigh belt recommended by the English operators. Their application seems to me entirely unnecessary, and I never yet have taken the precaution to secure the wrists, or to apply a binder to the thighs during a laparot- omy. The instruments and sponges are all carefully counted before the operation, and a record of their number made. This is very important, for, unless the precaution be taken, there is danger of leaving behind in the abdominal cavity, sponges or forceps OVARIOTOMY. 707 which have been introduced for the purpose of controlling hemorrhage. Usually one assistant is all that is necessary, especially if the operator has had extended experience. It is, however, wise to have at hand a second assistant whose duty it is to aid the first should complications arise calling for his services. In removing very large solid tumors, the second assistant is often called upon to support the tumor while the pedicle is being tied. He can also hold the edges of the abdominal wound together while the first assistant attends to the sponging and aids the operator in securing the sutures. Chloro- formist Table for Patient's head FIG. 158. Senior Assistant Receptacle for fluid, under Table for patient's body O Chief Junior Nurse Assist. table Operator Instrum Trays for ts Spray Window of Ward Pans for Sponges POSITION OF Tables, Operator, Assistants, etc., DURING OVARIOTOMY (Doran). Fig. 158 will explain the proper position of all who take part in the operation, as well as the proper arrangement of the tables, the instruments, and the receptacle for the contents of the cyst. Anesthetics. Unless the patient is suffering from bronchitis, or from kidney lesion, ether is by all odds the preferable anes- thetic.* Elderly patients with a tendency to bronchitis will sometimes bear chloroform better. Abdominal Incision.-After the patient is thoroughly anes- thetized the operator takes from the tray four or five pairs of catch-forceps (Fig. 159), a pair of elbowed scissors (Fig. 160), * The urine should always be examined previously to the administration of ether. 708 A TEXT-BOOK OF GYNECOLOGY. and a suitable scalpel. The catch-forceps he places upon the sterilized towel above the field of operation so as to have them conveniently at hand. There is a most decided advantage in having the scissors elbowed. An incision is now made through FIG. 159. CP G.TIEMANN & CO тов CATCH-FORCEPS. G.TIEMANN & CO FIG. 160. ELBOWED Scissors. the skin and superficial fascia of the median line, with one stroke of the knife. The average length of this incision is three inches. Spurting arteries are at once caught with the catch-forceps, which are permitted to remain attached until after the peritoneum OVARIOTOMY. 709 is opened; ordinarily a few minutes' compression will control the bleeding from any vessel severed at this stage of the opera- tion; it is rarely, if ever, necessary to resort to ligatures or tor- sion. If the abdominal wall is much stretched by the tumor, it is usually possible to make the incision between the recti muscles so that the sheath of neither is opened into. This cannot be so readily done when the abdominal walls are not stretched, as in oophorectomy. While it is always desirable to reach the peri- toneum without exposing the recti muscles, the abdominal wound will heal quite as well should their sheaths be opened into. A small area is next cleared from the subperitoneal fat, through which the peritoneum is caught up by a pair of catch forceps and pulled forward. A second pair of catch-forceps is attached a short distance from the first, and a small puncture with the point of a scalpel is made between them. The forefinger, or a director (Fig. 161), is now inserted into the abdominal cavity, FIG. 161. G.TIEMANN & CO. DIRECTOR FOR DIVIDING PERITONEUM. the abdominal parietes lifted away from the tumor or the intes- tines, and the peritoneum opened nearly as far as the skin wound by means of the scissors. I do not think it best to use the director before the peritoneum is reached. It requires unnecessary time to look for the indi- vidual layers and dissect carefully through them with the scalpel and director. Experience will enable the operator to determine by touch the thickness of the abdominal walls, when he can cut directly down to the subperitoneal fascia with one or two strokes of the scalpel. All bleeding points should be controlled before the peritoneum is opened. The length of the incision will necessarily depend upon the nature of the operation. In oöphorectomy, and in thin-walled unilocular cysts, it need not be over two inches. On the other hand, it is sometimes necessary, in removing large, solid growths to make the incision the entire length of the ab- 710 A TEXT-BOOK OF GYNECOLOGY. domen. I cannot see the advantage of endeavoring to work through too small an incision. To make it sufficiently large to enable the operator readily to get at the contents of the abdomen, when extensive intra-abdominal manipulation is neces- sary, seems to me better practice than to work under the restric- tions and embarrassments incident to a short incision. A long incision does not in the least prejudice the prognosis. Occasionally the tumor is so intimately adhered to the peri- FIG. 162. EMMET'S OVARIOTOMY TROCAR. FIG. 163. G.TIEMANN & CO. GTIEMANN & CO. SPENCER WELLS'S OVARIOTOMY TROCAR. toneum as to make it difficult to distinguish the latter from the cyst wall. More than once has the peritoneum been stripped from the abdominal wall, the operator laboring under the im- pression that he was removing the adherent cyst wall from the peritoneum. The existence of such adhesions may be suspected if the hemorrhage attending the abdominal incision is greater than normal, or if the intramuscular fasciæ are of a deep pink color. Ordinarily the operator will recognize that he is stripping OVARIOTOMY. 711 the peritoneum by the deep red color of the underlying struc- tures. If there is ascitic fluid this should be permitted to escape as soon as the peritoneum is opened, the assistant pressing upon both flanks in order to force it out. Ascites is especially liable to exist when there are cancerous or papillomatous growths within the pelvis. Intra-abdominal Manipulations.-An ordinary ovarian cyst will be recognized after the abdomen is opened by its smooth, FIG. 164. G.TIEMANN & CO WILCOX'S CYST FORCEPS. FIG. 165 ¿G.TIEMANN &COF SPENCER WELLS'S CYST FORCEPS. shining, white surface. The operator should now wash his hands in sterilized water and make an exploration with his finger or fingers. Should the intestines make their appearance, they are kept out of the way by the assistant, who places sponges about the tumor in such a way as to prevent their protrusion. Tapping the Cyst.-After the cyst is exposed and the opera- tor is reasonably sure of its nature, the tapping trocar (Figs. 162, 163) is thrust into it, and the fluid permitted to drain off. 712 A TEXT-BOOK OF GYNECOLOGY. As the cyst wall collapses it should be seized with a pair of cyst forceps (Figs. 164, 165), and pulled upward through the ab- dominal incision. By doing this the intestines will be prevented from escaping and the fluid from finding its way into the peritoneal cavity. At this stage, should a piece of adherent omentum be withdrawn with the cyst, an effort should be made to detach it with the sponges; if this cannot be done it should be caught in a pair of catch-forceps and its distal end divided. If the cyst does not completely collapse, it is probable that it is multilocular. After the large loculus is emptied the trocar is carefully thrust into the smaller ones, thus emptying them one by one, if it is possi- ble to do so. Sometimes the fluid will be too thick to pass through the canula, in which event it will be necessary to with- draw the canula and make an incision into the cyst large enough FIG. 166. GTIEMANN 500- SPENCER WELLS'S T-FORCEPS. to admit the hand. The edges of the opening in the cyst are then grasped on each side with strong T-forceps (Fig. 166), the hand introduced, and the contents scooped out. If there are no adhesions, the cyst, after it is emptied, can be drawn through the incision and its pedicle secured. If, on the other hand, adhesions exist they must be dealt with according to the methods presently to be described. The advantage of empty- ing the cyst before undertaking to separate the adhesions lies in the greater readiness with which adhesions can be treated and re- sulting hemorrhage controlled. There is also less danger of lacerating the intestines and other important abdominal and pelvic viscera. OVARIOTOMY. 713 Management of Adhesions.-In the management of adhe- sions it is necessary to bring into action fingers, sponges, forceps, scissors, and ligatures. Recent adhesions can ordinarily be separated by the fingers alone, or by the use of sponges. On the other hand, when they become firm their separation often taxes the patience and skill of the operator to the utmost. Those existing between the omentum and the tumor are the most easily dealt with. If they cannot be separated by the finger or by sponging, they may be caught between two catch-forceps and divided; the proximal end can afterwards be tied with catgut. Adhesions to the abdominal parietes can also be separated in most instances by the use of sponges. In the worst cases, unfortu- nately, this cannot be done, and they may be so firm as to make it necessary to leave the cyst wall, or portions of it, behind. Special care must be observed in separating adhesions from the intestines, the liver, and the lower part of the pelvic cavity in close proximity to the ureters and the large vessels. Long adhe- sions may be first caught in catch-forceps, separated, and tied after the cyst is removed. If there is much oozing of blood this must be temporarily controlled by sponge-packing. It may be necessary, before the abdomen is closed, to sear the parts with the Paquelin, or to apply directly to the bleeding surface a solution of iodin. The T-shaped forceps (Fig. 159) are exceed- ingly useful in dealing with oozing of this kind. They may be left on for five or ten minutes. Treatment of the Pedicle.-In the past all sorts of methods have been resorted to for the purpose of securing the pedicle. It has been burnt off, crushed off, tied entire, tied in sections, and secured in clamps and left outside of the abdomen to slough away. At the present time the methods of securing the pedicle have practically resolved themselves into two-the clamp and cautery, and the ligature. The mortality of ovariotomy dropped at once when the extra-peritoneal method was discarded and the intra- peritoneal adopted. In nearly all instances it is entirely possible to deal with the pedicle so that it can be dropped into the peri- toneal cavity. Keith is the chief advocate of the clamp-and-cautery method, 714 A TEXT-BOOK OF GYNECOLOGY. and in his hands it has reached its highest degree of perfection. The clamp represented in Fig. 167 is first applied, and the tissues of the pedicle crushed. The pedicle is severed about an eighth of an inch from the clamp, after which the cautery is applied. until there is left a" thin, gray, translucent band of anemic but still living tissue." (Greig Smith.) The clamp is now removed, and after making sure that all hemorrhage is controlled, the pedicle is returned to the abdominal cavity. Properly prepared silk is the ligature now almost universally used for securing the pedicle. The size of the silk will vary FIG. 167. KEITH'S OVARIOTOMY CLAMP. FIG. 168. FIEMAN N=& GTIEMANN & CO. CLEVELAND'S LIGATURE FORCEPS. according to the vascularity and size of the pedicle. It is not necessary that it should be large, yet it should permit of suffi- cient traction to secure the stump very firmly. The ligature is made to transfix the pedicle by means of a pedicle needle, or, better still, by means of Cleveland's ligature forceps (Fig. 168). After the forceps transfixes the pedicle, the blades are opened sufficiently to permit the assistant to slip into them the loop of ligature; the blades are then closed and the instrument withdrawn, bringing with it the double ligature. The ligature can now be secured according to one of two OVARIOTOMY. 715 methods. In the first method the ligature is cut in two, the two ends thrown over each other so that when tied on either side there can be no splitting of the pedicle. It is best first to secure the ligature by a friction-knot; the tumor is then cut away, leav- ing about half an inch of the pedicle above the knot. The ligatures can now be tightly drawn and secured with a final hitch. • FIG. 169. The second method is that known as the Staffordshire knot, first adopted by Lawson Tait. It is shown in Fig. 169. In order to understand the method of making this knot, let the reader pass a double string between two fingers of his left hand. Throw the loop of the string over the ends of the fingers; then place one of the free ends. under the loop and one over it. If the two free ends are now tightened by a knot he will find that the fingers, representing STAffordshire Knot. the two sides of the pedicle, will be drawn closely together. This is a very satisfactory knot, especially for small pedicles. If the pedicle is very large and thick, I prefer the first method. Should the pedicle be too large to include in one loop, it may be transfixed in two or more places and the several sections tied separately. After the pedicle is secured, whichever method is adopted, it is my practice to sear the surface of the stump with the cautery. Perhaps this is an extreme precaution, but it is a practice observed by many of the German operators. It is an additional safeguard against hemorrhage, and there is less ten- dency for the pedicle to contract adhesions after the cautery has been applied. The opposite ovary is now explored, and if there are any evidences of disease this is also removed. Cleansing the Peritoneal Cavity.—If no fluid has escaped into the peritoneal cavity, and there have been no adhesions, all that is necessary to do is to close the abdominal wound without drainage. On the other hand, if the intra-abdominal manipula- tions have been extensive and the oozing at all marked, or if some foreign substance has escaped into the abdomen, especially 716 A TEXT-BOOK OF GYNECOLOGY. septic fluid or colloid material, it is necessary to take every pre- caution to cleanse the abdominal cavity most thoroughly before closing it. There is no better way of accomplishing this than by free irrigation, a procedure popularized by Keith and Tait. A special apparatus, consisting of a siphon arrangement through which the water is conducted into the abdominal cavity, has been devised for this purpose. However, I think it is quite as well to pour the water from a pitcher while the operator or his assistant separates the abdominal wound with the two hands. The abdomen is completely filled with the fluid, the intestines being so manipulated as to wash away any septic matter or débris which may have been left behind. The water is then removed by pressing upon the flanks and forcing it out, and by sponging. The washing is repeated as often as may be neces- sary to remove the débris. If there is general oozing that cannot be controlled by the ordinary measures, the abdomen may be left filled with the sterilized water, which can be drawn off later through a drainage tube. Warm water used in this way is also exceedingly valuable in overcoming shock. I have seen patients almost in a state of collapse rally quickly after its use. The temperature of the water should be about 105° F. way Should none of the contents of the cyst have found their into the abdominal cavity, it is only necessary to remove any sponges which may have been placed in the abdomen during the operation, and to clean the Douglas, and the lateral pelvic pouches. This is best done by sponges attached to sponge holders or long forceps. It is, to be sure, a good thing to leave the peri- toneal cavity clean. On the other hand, it is entirely possible to overdo the matter of cleansing it. There is no doubt that much injury has been done in the past by the extreme measures re- sorted to in completing the toilet of the peritoneum. Too much rubbing and friction in the effort to remove every particle of fluid will only cause unnecessary irritation. If the fluid that is left behind is not septic, the peritoneum will absorb a reasonable amount of it without either disturbing the system or prejudicing the prognosis. Drainage. The object of drainage is to remove the fluid which the peritoneum secretes as a result of the irritation inci- OVARIOTOMY. 717 dent to the operation, as well as to remove the products of the oozing from sero-sanguinolent surfaces. The absorbing power of a healthy peritoneum is very great, and in most instances the fluid secreted is absorbed. However, it occasionally happens that it is impossible to control all of the oozing of blood; or it may be impossible to remove all of the foreign matter which has found its way into the peritoneal cavity. It is, therefore, not- withstanding modern antisepsis, frequently necessary to resort to drainage, though the surgeon who practises antisepsis will undoubtedly have less occasion to use drainage than the one who does not. It is not an easy matter to determine just when drainage is indicated; hence, the maxim set forth by a well-known surgeon is a good one to follow, viz.: "When in doubt, drain.” I have, in Chapter XII, described the method of Mikulicz FIG. 170. FIG. 171. G.TIEMANN &CO. G.TIEMANN &CO. THOMAS'S CURVED NON-PERFORATED THOMAS'S CURVED PERFORATED DRAIN- DRAINAGE-TUBE. AGE-TUBE. of Vienna, who uses iodoform gauze for the purpose of packing large bleeding or absorbing cavities in the abdomen, bringing one end of the gauze out of the abdominal wound. The de- odorant quality of the gauze prevents it from becoming offensive, and it can be left in place for several days. Thus used, it not only acts as a hemostatic but as a capillary drain as well. When the object is not to control hemorrhage, but simply to afford an exit for the fluid which gravitates into the cul-de-sac of Douglas, glass drainage-tubes are preferable. Those shown in Figs. 170 and 171 are the ones most commonly used. They are nothing more than glass tubes open at both ends, the lower end being perforated at its sides. The upper end is made funnel- shaped so that it cannot slip into the abdominal cavity. Care should be taken to select a tube sufficiently long to reach the 718 A TEXT-BOOK OF GYNECOLOGY. bottom of the cul-de-sac of Douglas, while the flange rests upon the skin surface; this prevents injurious pressure upon the rectum. The tube is introduced either before or after the liga- tures are passed. Douglas's pouch being the most dependent part of the abdomen, the fluid gravitates into it and can be drawn off through the tube. The upper end of the tube is pro- tected by a sheet of rubber slipped over it, which should be suf- ficiently large to enclose a sponge placed over the mouth of the tube. A very simple device for drawing off the fluid is an or- dinary glass syringe, to which is attached a piece of rubber tub- ing long enough to reach the cul-de-sac through the tube. This should be used every two, three, or four hours, depending upon the quantity of fluid secreted. If not more than two drams of sero- sanguinolent fluid are secreted during an interval of two or three hours, the tube is no longer needed, and should be withdrawn, after which the opening in the lower end of the wound is closed by tying the provisional sutures, which were introduced for that purpose. * Closing the Abdominal Wound.—After making sure that all hemorrhage is controlled, the operator may proceed to close the abdominal wound. Many plans for doing this are in vogue. Some surgeons prefer to close the successive layers of tissue by continuous catgut sutures, bringing the integument together by interrupted silk sutures. The method most generally adopted is the interrupted silk suture passed through all of the tissues— peritoneum, fascia, and skin, or, peritoneum, fascia, muscle, and skin, as the case may be. The surgeon should aim to have as broad a union as possible. It is, therefore, best to include all of the tissues in the sutures. About three sutures are inserted to the inch. Before they are passed a large, flat sponge should be placed over the intestines underneath the wound in order to catch any hemorrhage that may result from the needle punctures. I prefer the trocar-pointed straight needles for this purpose. They readily penetrate the tissues, and no needle holder is re- quired. After the sutures are all passed the ends on either side * I have purposely described in this section the management of the drainage tube throughout the after-treatment, although its consideration would more naturally come under the latter head. OVARIOTOMY. 719 are caught in catch-forceps. The surgeon now has the forceps and sponges counted. He then removes the sponge which was placed underneath the wound while passing the sutures, and makes a final exploration to make sure that there has been no hemorrhage. The omentum should next be drawn down and spread out over the intestines. The assistant, unlocking the catch-forceps attached to the ends of the ligatures, lifts the abdominal wound by them. The wound is sponged with a 1 : 3000 bichlorid solution (no antiseptic is used within the abdominal cavity), and the surgeon proceeds to tie the ligatures, beginning at the lower end. If a drainage-tube has been introduced, the first one or two ligatures are tied in a bow-knot, so that when the tube is withdrawn the ligatures can be drawn tight and the opening closed. Care must be taken not to produce too much tension upon the sutures in tying. The irritation thus produced may result in stitch-boil abscesses in spite of every antiseptic precau- tion. After the edges of the wound are nicely coaptated, and the sutures all tied, the latter are cut close to the knots by grasp- ing all of them in one hand and quickly severing them, one by one. Should the skin surface not be nicely coaptated, it can be brought together by a continuous catgut suture. Dressing the Wound at the Close of the Operation. The mackintosh is now removed and the abdomen washed with a 1:3000 bichlorid solution and dried with a sterilized towel. Iodoform is sprinkled over the wound and a small strip of sur- geon's silk applied. Over this is loosely placed a liberal supply of iodoform or bichlorid gauze. Next a large pad of antiseptic absorbent cotton is placed over the gauze. A many-tailed binder is finally applied, which will, when firmly secured with safety pins, support the abdomen and hold the dressings in place. If a drainage-tube has been introduced, the dressings are nicely fitted about the tube at the lower end of the wound. Care must be observed not to permit the bandage to exert undue pressure upon the tube; it should, however, be sufficiently tight to keep the tube from being forced out should the patient retch. The patient is now placed in bed and given in charge of the nurse. The bed should be protected with a mackintosh and covered with a drawn sheet arranged in several folds. The knees are supported 720 A TEXT-BOOK OF GYNECOLOGY. by a pillow placed underneath them. If the operation is performed in the room where the patient is to remain, all instruments, appliances, tables, receptacles, etc., should be removed before the patient recovers from the anesthetic. In the foregoing description I have confined myself to ordi- nary cases of ovarian cysts, where the adhesions, if present, are not sufficiently extensive to prevent the removal of the tumor. I have also presupposed the existence of a pedicle capable of liga- . ture and management in the usual way. It now becomes necessary to discuss the management of those cases where no pedicle exists, or where it is impossible, because of extensive adhesions or other complications, to remove the cyst wall. Incomplete Ovariotomy.—Incomplete ovariotomy may end in exploratory incision when the surgeon finds that, owing to the complications before mentioned, or owing to the existence of malignancy, it is deemed unwise to proceed further. He then closes the wound, with or without drainage, as the conditions suggest. In other instances, he will, perhaps, have undertaken to remove the cyst wall; but owing to the extensive adhesions, or to the fact that the cyst is intra-ligamentary and cannot be enucleated because of its deep attachment in the pelvis, he will not dare to close the wound in the ordinary way. It is then necessary to retreat in good order. All hemorrhage must first be checked by securing the vessels on and within the tumor, as well as those within the abdominal cavity. The surgeon, by carefully inspecting all points that were adherent, must convince himself that the intestines have not been injured. The abdom- inal cavity is then cleaned as thoroughly as possible; if the contents of the cyst have escaped into it, it may be necessary to combine, with drainage of the cyst, abdominal drainage as well. If the abdominal wound is longer than usual, its upper part should be closed by sutures. The opening made in the cyst is now enlarged and stitched to the walls of the incision, as is shown in Fig. 172. The sutures are passed in such a way that about a quarter of an inch of the peritoneum is brought in con- tact with the cyst wall. After the sutures are tied the cyst will be entirely cut off from the peritoneal cavity. This is the same OVARIOTOMY. 721 method as that adopted in the management of extra-uterine gestation cysts, which cannot be removed, and in the treatment of pelvic abscesses. The surgeon should break down any septa that may shut off loculi from the main cyst, and wash the cavity with a weak carbolic solution, or with strong iodin. A drainage- tube is finally placed at the most dependent portion of the cyst; through this the cavity can be washed as often as is necessary in order to keep it clean. It is surprising how quickly a large cyst cavity thus treated will contract and fill in with granulations. I have seen a large FIG. 172. INCOMPLETE OVARIOTOMY. suppurating ovarian cyst, which contained nearly three gallons of purulent matter, become completely obliterated in less than two months' time following the operation. Encapsulated Ovarian Cysts.-In studying the pathology of ovarian tumors, it was shown that the cysts occasionally grow down between the layers of the broad ligament. As the tumor continues to enlarge it distends these layers and separates them. I have seen a cyst of this kind dissect the anterior layer of the broad ligament and the peritoneum nearly to the diaphragm. 46 722 A TEXT-BOOK OF GYNECOLOGY. The capsule is, therefore, formed by the layers of broad liga- ment. It is usually of a very pale red color, which contrasts strongly with the white, glistening cyst wall ordinarily met with. The parts are greatly disturbed by the cyst growing in this way. Sometimes the cyst may burrow deeply enough to attach itself to the pelvic fascia, when its close proximity to the ureters and the large vessels makes these important structures exceedingly liable to be injured. It occasionally happens that there is sufficient space between the uterus and the tumor to form a true pedicle, notwithstanding the presence of the capsule; if so, the capsule can be removed entire with the tumor. Unfortunately, this is rarely the case. In most instances it will be necessary to enucleate the cyst from the capsule. An effort is first made to brush or sponge the capsule from the cyst wall as the latter is being withdrawn. Sometimes the adhesions are so slight as to make it possible to do this; oftener, however, it is necessary to incise the capsule high up and to dissect it off with the fingers or with the handle of a scalpel. During the dissection care should be observed not to perforate or lacerate the capsule in any way. When the hemorrhage proceeds from spurting vessels, these must be caught and tied with fine catgut; or, should it amount to nothing more than an oozing, it may be controlled by sponge packing. As the enucleation proceeds, the base of the cyst is finally reached at the deepest part of the capsule, when an effort should be made to detach the cyst entirely. It is while endeav- oring to detach the cyst at its base that the large vessels and ureters are liable to be injured. It is now necessary to care for the emptied capsule. Some- times it is possible to constrict its base into a pedicle, when it is transfixed, tied, and cut off, in the ordinary way. If, however, the mass of tissue included in the ligature is at all great, its free edges should be brought together above the ligature by a con- tinuous chromacized catgut suture. If the base of the capsule lies so deep in the pelvis as to make this method of treatment impracticable, the capsule should be drawn through the abdominal wound, the greater part of it cut away, and the remainder stitched to the edges of the wound, as in incomplete ovariotomy (Fig. 172). OVARIOTOMY. 723 Care should be taken to see that neither intestine nor omentum protrudes through any openings in the capsule; indeed, such openings should be entirely closed so that the interior of the cap- sule is perfectly cut off from the peritoneal cavity. A glass drainage-tube is now placed in the capsule. Finally, the peri- toneal cavity is cleaned, and, if necessary, drained at the side of the capsule, the principles of drainage already given being observed. It may be impossible to remove the base of the cyst from the capsule. Indeed, it is sometimes necessary to leave portions of non-capsulated cysts behind when the base is strongly adhered. In instances of the kind, an effort should be made to remove as much of the solid growth from the base left behind as is pos- sible. It is hardly necessary to add that drainage is here im- perative. CHAPTER XLVII. OVARIOTOMY (Continued.) AFTER-TREATMENT-ILLUSTRATIVE CASES. After-treatment.-The after-treatment of ovariotomies, or laparotomies made for any purpose, cannot be properly carried out without the coöperation of an intelligent nurse. There is no class of nursing that requires greater skill than does the nursing of abdominal cases. It has been said by a well-known surgeon that the fate of every patient undergoing laparotomy is determined before she is removed from the operating-table, but to this statement I cannot entirely agree. The best directed efforts of the surgeon may be defeated by the ignorance or the wilful neglect of the nurse. This is especially true if a drainage-tube is used; so long as the tube is in situ the abdomen is exposed to contamination from without. The most rigid anti- sepsis may have been observed by the operator and his assist- ants and yet the abdominal cavity may be infected through im- proper care on the part of the nurse. She should, therefore, first of all, be thoroughly familiar and in sympathy with the details of antisepsis. She should know how to use the catheter and the ice- cap. She should be perfectly capable of taking the pulse and the temperature. She should know how to prepare and administer nutritive enemata. She should be able to empty the drainage- tube as often as may be necessary. She should keep an accu- rate clinical record, to which the surgeon can refer at each visit. She should be able to recognize symptoms of shock, collapse, and internal hemorrhage. And, finally, she should possess suf- ficient moral courage rigidly to adhere to the surgeon's direc- tions, despite the pitiful appeals which patients often make for cold water or unlimited quantities of ice. Notwithstanding the numerous requirements indicated in the foregoing, the after-treatment of an ordinary case of ovariotomy 724 OVARIOTOMY-AFTER-TREATMENT. 725 consists mainly in not doing certain things which are harmful. After the patient is placed in bed she should be kept as quiet as possible until she returns to consciousness. The bed should be previously warmed by means of a warming-pan or hot water- bags; but the latter should be removed before the patient is placed in bed. Unless this is done there is great danger of burning her. It has been my misfortune to have had several patients, while under the influence of anesthetics, severely burned by hot water-bags or bottles. No matter how emphatically the nurse is cautioned regarding their use, they are liable to come in contact with the skin surface and do harm. I have, therefore, discarded them entirely, except for the purpose of warming the bed previously to transferring the patient to it. If the patient has been properly dieted for the operation, vomiting may not be excessive. Ordinarily, however, vomiting will continue with more or less persistence for the first twenty- four hours following the operation. The patient will also com- plain, in most instances, of intense thirst. Cold water will aggravate both the vomiting and the thirst; consequently, nothing but hot water should be given, and that in small quantities and as hot as the patient can sip it. It is worse than useless to under- take to force nourishment while there is irritation of the stomach, for the vomiting will only be aggravated by it. Should vomiting persist, relief may be obtained by washing the stomach with a glass of warm (not hot) water, and encouraging the patient to eject it at once; more or less bilious matter will be thrown off with the water. If the patient cannot tolerate the hot water, and the thirst is marked, it may be ameliorated by an enema consisting of a pint of warm water, to which may be added, in case the tympanites is distressing, a few drops of turpentine. The water in the rectum is absorbed, and the intense thirst more or less relieved. Stimulants are counter-indicated unless to overcome serious shock and collapse. They may then be used in the form of hypodermic injections of brandy, or as enemata. If administered hypodermatically, a dram of brandy or the best rye whiskey may be used at each injection, and as often as is necessary; if admin- istered per rectum two ounces of brandy in a pint of warm water 726 A TEXT-BOOK OF GYNECOLOGY. should be thrown into the lower bowel. In the event of heart failure, hypodermic injections of strychnia sulph., digitalin, strophanthus, or glonoin, may be resorted to. In addition to the foregoing, the general measures useful for overcoming shock, under whatever circumstances it occurs, should be applied. The external application of warmth, friction of the body, lower- ing the head, cloths wrung from hot water applied to the pre- cordial region—any or all of these measures may be brought into requisition if necessary. If the patient can urinate spontaneously, she is permitted to do so from the very first; if not, the catheter must be used as often as every six hours. (v. Chapter XII). After twenty- four hours, if the vomiting ceases, small quantities of nourish- ment may be given. It should at first be of the blandest character. A good article to begin with is crust coffee, in teaspoonful doses every hour, increasing the amount hour by hour, if the stomach will tolerate it. In the course of eight or ten hours a tablespoonful of kumyss, weak beef tea, or milk with lime water, may be substituted for the crust coffee. The patient's condition does not call for nourishment during the first twenty-four hours following the operation. Even if it is not ejected by the stomach the system will rarely assimilate it in any quantity and more harm than good follows its adminis- tration. Usually patients are not hungry, and symptoms of prostration, should they supervene, are best overcome, not by food substances, but by stimulants. Unless a drainage-tube has been introduced, the patient should be permitted to lie in the position which affords her the most comfort. She should not, however, be permitted to throw herself about in the bed. When she turns it should be with the help of the nurse. She should be encouraged to lie in one position at least an hour at a time. If the case runs a normal course, there should be no rise whatever in the temperature or pulse. The amount of pain is ordinarily much less after the removal of large ovarian cysts than it is after oophorectomy. The bowels should be moved on the third day by an enema. The dressings should be changed on the seventh day, at which time a part of the stitches OVARIOTOMY-AFTER-TREATMENT. 727 may be removed. It is usually best to leave behind every other suture for a couple of days longer, though, if there are evidences of irritation, all should be removed at once. After the stitches are removed, it is well to support the edges of the wound for a week or ten days with strips of adhesive plaster, around which the abdominal bandage is placed. It is quite safe for the patient to sit up in bed on the fourteenth day; and it is entirely possible for her to get out of bed, even after most severe operations, on the sixteenth or eighteenth day without serious risk. At the end of the twenty-first day, or, if she does not gain strength rapidly, at the end of the twenty- eighth day, she may return to her home. She should be in- structed to wear an abdominal supporter or bandage for at least six months. Unless this precaution be taken there is danger of hernia resulting from stretching of the cicatrix. Such is the course which a normal case of ovariotomy, in these days of antisepsis, will run, in perhaps the majority of instances. The reader must not, however, imagine that every case will ter- minate so favorably and give rise to so little anxiety. Certain complications are liable at any time to arise, and this chapter would be incomplete did they not receive consideration. The Pulse and Temperature.-While, as has been intimated, the pulse and temperature should remain normal, they frequently become perverted, even markedly so, without interrupting the favorable progress of the case. Thus, it is not uncommon for the temperature to rise a degree, or even two degrees, during the first two or three days succeeding the operation. This is usually due to the absorption of fluid which is either left behind, or is poured into the abdominal cavity because of the peritoneal irritation attending the operation. I have more than once known the temperature to rise in this way without any other evidence of peritonitis, pain being absent, and the patient suffer- ing not the least inconvenience. If, however, the rise in tempera- ture is associated with pain in the bowels of a sharp lancinating character, and with other symptoms indicating peritonitis, it is, of course, significant, and requires especial attention. The pulse, too, may become perverted without a correspond- ing rise in the temperature. I have known it to be as high as 728 A TEXT-BOOK OF GYNECOLOGY. 140° for three or four days following the operation, while the temperature remained perfectly normal. In all of my cases where this occurred, convalescence was uninterrupted, the pulse-respira- tion ratio becoming normal in due time. It is difficult to explain the very great rapidity of the heart's action in instances of the kind. Possibly the shock attending the operation, although not mani- festing itself in other ways, so affects the inhibitory apparatus of the heart as to permit the latter to run away with itself; or, as suggested by Mundé, it may be due to purely mental causes. At any rate, this disparity between the pulse and the temperature no longer alarms me when the patient seems to be doing well in every other respect. If the temperature is subnormal with a pulse of this kind, the disparity is usually due to septic peritoni- tis. Septic peritonitis, however, impresses the system so pro- foundly that other symptoms of this most dangerous complica- tion stand out prominently. Tympanites.—This is a frequent and distressing complica- tion; it is ordinarily an expression of peritonitis, though flatu- lency may occur without inflammation. When not a feature of peritonitis, it is due to the disturbance of the intestines during the operation, and to the diminished intra-abdominal pressure re- sulting from the removal of large growths. The indicated remedy -colocynth, china, lycopodium, bryonia, etc.-will often afford most decided relief when more radical measures are not called for. If relief is not afforded by internal medication, a rectal tube should be passed which will often permit the gas to escape. If the latter expedient fail, turpentine or peppermint enemata may be tried. Finally, if these several measures are unsuccessful, the existence of peritonitis is probable, in which event the saline cathartics should at once be resorted to. Septicemia and Peritonitis.-I include these two complica- tions under one head, for the reason that peritonitis, in by far the larger number of cases, is due to septicemia. The fact that a slight increase in temperature not infrequently supervenes after laparotomies has already been noted. If this rise be due to the absorption of a limited amount of fluid, or even septic matter, the system is perfectly able to eliminate the poison, and the case will progress to a favorable termination; in OVARIOTOMY-AFTER-TREATMENT. 729 obstetric parlance this is nothing more than a slight septic in- toxication. On the other hand, if germs have found their way into the abdominal cavity during the operation, or if septic matter has been left behind in such quantities, and of such a character, as profoundly to impress the system, the surgeon will have to con- tend with the double complication of septicemia and peritonitis. These complications usually manifest themselves during the first few days following the operation; rarely do they appear after the seventh day. If the convalescence has progressed normally for the first five or six days, the sudden rise in temperature is usually due to causes other than septicemia. The symptoms of septicemia and peritonitis are: a high tem- perature, pain, tympanites, vomiting, and prostration. Some of these symptoms usually stand out more prominently than others. The tympanites and vomiting are particularly obstinate. There is something more than a simple elevation in the infra-sternal region which may be present in perfectly normal cases. The distention of peritonitis is "drum-like," and it may be sufficiently great to interfere with respiration. If the frequent association of the two affections, septicemia and peritonitis, was fully comprehended by the surgeon of even ten years ago, certainly the treatment was conducted upon the most unscientific principles. The practice of administering opiates, then in vogue, is now deprecated by surgeons of all schools. In their stead the saline cathartics are used. This practice was, I believe, inaugurated by Tait, and it is one of the most satisfactory procedures in abdominal surgery. As soon, therefore, as symptoms of septicemia and peritonitis present themselves, an effort should at once be made to move the bowels with a saline cathartic. A seidlitz powder.may be given, and repeated in the course of four hours if the first does not produce the desired result. If the stomach is irritable, as it usually is, it is best to give the dissolved powder in small quan- tities at intervals of five minutes. Should this fail, small doses of calomel may be given in 1-10 grain tablets every half hour until fifteen or twenty are taken, followed by teaspoonful doses every half hour of Rochelle or Epsom salts, until four or five doses are 730 A TEXT-BOOK OF GYNECOLOGY. taken (Mundé). The action of the cathartic may, if necessary, be supplemented by enemas of oil or ox-gall. The cathartics are purely eliminative in their action. The free movement of the bowels will ordinarily relieve the tympanites, the vomiting, and the high temperature. If the bowels remain obstinately closed in spite of the cath- artics and enemas, there is probably an intestinal obstruction, and no time should be lost in reopening the abdomen and seeking the cause of the obstruction. It is true that this is a most desperate procedure, for, no matter how simple the primary operation may have been, it is quite a different thing to open the abdomen with the intestines enormously distended with gas. After the obstruction is overcome, the intestinal distention should be relieved by making, with a fine hypodermic needle, numerous punctures into them, through which the gas is permitted to escape. The intestines are then returned to the abdominal cavity, the abdomen is washed with sterilized water in which the intestines are left floating, and the abdominal wound reclosed. A drainage tube under the circumstances is imperative. If the vomiting persists, the stomach must be given absolute rest by administering all nourishment through the rectum. The rectal food should be given in such a form as to produce the best possible results with a minimum of disturbance. This object is attained by using food which has been previously digested and which possesses great nutritive properties. A favorite nutrient enema of mine is half an ounce of bovinin and four ounces of peptonized milk, to which may be added, if indi- cated, an ounce of brandy. This should be repeated every four or six hours, as the exigencies of the case demand. This chapter would be incomplete without a list of the homeo- pathic remedies oftener used in contending with the conditions and complications described, together with their indications. I have so often seen good results follow the administration of properly selected remedies in the conditions dealt with, as to make me confident that the abdominal surgeon who does not use them is depriving his patient of most valuable agents. I am also sure that the homeopathic surgeon will be compelled to resort to opium much less often than will the surgeon who is un- OVARIOTOMY-AFTER-TREATMENT. 731 familiar with the specific action of the remedies whose indications I give. However, nearly all surgeons now restrict opium, in the after treatment of laparotomies, to those cases where the pain and restlessness are so great that it is utterly impossible to keep the patient quiet without its aid. It is then best administered in the form of hypodermic injections of morphia. Therapeutics. Colocynth.-Abdomen distended and painful; great tympani- tes; incarcerated flatus; cramp-like pain in both sides of abdo- men; severe colicky pains, mostly around the navel; great rest- lessness and loud screaming on change of position; relieved by drawing knees up. Bryonia.-Griping pains about the navel; constant painful cutting pains in the intestines, with the feeling as though some one were digging her with the fingers; great sensitiveness of abdomen; ALL SYMPTOMS AGGRAVATED BY THE SLIGHTEST MOTION. Belladonna.-Distention of abdomen; the transverse colon protrudes all the way across the abdomen from incarcerated flatus; loud rumbling and pinching in the abdomen; SHOOT- ING, DARTING, CUTTING PRESSURE IN HYPOGASTRIUM; tenderness even to slight pressure, especially over ovarian region; CEREBRal EXCITEMENT. Arsenicum.-Rumbling in bowels; violent pains in abdomen, with great anguish; frequent hiccough, with constant nausea and vomiting; ineffectual retching; VOMITING IMMEDIATELY AFTER EATING OR DRINKING; intense thirst; great restlessness; SYMP- TOMS OF SEPSIS. Hypericum.-Especially indicated in nervous patients who suffer a great deal of pain, without inflammatory symptoms; tym- panitic distention of abdomen; cutting in belly in region of navel; stitches in small of the back; ACHING PAIN AND SENSATION OF LAMENESS IN SMALL OF BACK; jerking and twitching of the limbs; DYSURIA. Coffea.-Sleeplessness; fear of death; pain seems unendura- ble; colic, as if the stomach had been overloaded; cannot suf- fer the clothes to be tight over the abdomen; continuous pinch- ing pain in the iliac region. 732 A TEXT-BOOK OF GYNECOLOGY. Lycopodium.-Spasmodic contraction in the abdomen; colicky pain in the right side of the abdomen extending into the bladder, with frequent urging to urinate; ACCUMULATION OF FLATUS, WHICH BECOMES INCARCERATED; great fermentation in the abdomen, with rumbling; discharge of much flatus per anum; deposits of uric acid in urine. China.-Distention of abdomen with griping, and here and there a sharp pain; MUCH FLATUS, WITH RUMBLING; emission of flatus; especially useful after the loss of a large amount of blood, with dyspnea, ringing in the ears, etc. Nux vomica.-Pressure under the short ribs, as from incar- cerated flatus; colic, with pressure upward, causing dyspnea, and downward, causing urging to stool and urination. Ipecacuanha.-Constant NAUSEA, WITH RETCHING; vomiting of ingesta, and then of bilious matter; flatulent colic, with fre- quent stools; cutting about the umbilicus.* Illustrative Cases. It is my object to present, in the following series of illustrative cases, such only as are typical of certain conditions and com- plications dealt with in the text. • CASE LXXVI.—Ovariotomy for Ruptured Cyst. Recovery.-Patient, American, æt. 46. Referred to me by Dr. W. A. Winslow of Sylvania, Ohio. Married for 25 years. Four children; labor normal in all instances. Had always enjoyed good health up to a year before entering the hospital (October 3, 1892), at which time menstruation ceased. The menses were suppressed until the following August, when there was a slight flow. During the suppression she was free from headache, flashes of heat, and all of the usual symptoms attending the menopause. About three months before coming to the hospital she noticed for the first time an enlargement in the right groin, which grew very rapidly, the abdomen becoming greatly distended. Some four weeks before entering the hospital her husband, dur- ing sleep, struck the abdomen with his elbow. This was followed by severe and intense pain, with the symptoms of shock and collapse. The temperature immediately rose to 103°, and for two weeks she was confined to her bed with peritonitis. She entered the hospital October 3, 1892. The tenderness and abdominal pain were at that time most distressing. The temperature ranged from 100° to 102°. On October 11th the abdomen was opened. The cyst wall was so intimately at- tached to the anterior abdominal wall that it was unavoidably incised. The sac was adherent to the entire anterior and lateral abdominal parietes, though the adhesions, * v. Therapeutics of Acute Inflammatory Affections of the Pelvic Organs. OVARIOTOMY-ILLUSTRATIVE CASES. 733 being of recent origin, were separated by the fingers and by sponges with no great difficulty. There was much oozing from the site of the adhesions, which was con- trolled by sponge packing. A large quantity of ascitic fluid was within the abdominal cavity. The pedicle was easily secured and cut away; after which the abdomen was thoroughly washed with sterilized water, a drainage tube inserted, and the wound closed. The temperature immediately dropped to normal, and remained so throughout the convalescence. There was no shock following the operation. The drainage-tube was withdrawn on the second day; the stitches were removed on the seventh; the patient sat up in bed on the tenth, and was discharged perfectly well on November 3d, just one month from the day she entered the hospital and three weeks from the date of the operation. CASE LXXVII.-Large Unilocular Ovarian Cyst, with Hemorrhage into its In- terior. Great Rapidity of Pulse following Operation without Corresponding Rise in Temperature. Recovery.-Patient æt. 23. Referred to me by Dr. Young of Pioneer, Ohio. She entered the hospital on April 29, 1892. Two years previously to that time the abdomen began to increase in size. For fourteen weeks before entering the hospital the enlargement was uniform, centrally located, and was so large as to cause marked difficulty in breathing when lying down. The menses continued normal and her gen- eral health was not seriously compromised, though pressure symptoms had begun to manifest themselves. The abdomen was opened on May 3d. The contents of the tumor were drawn off through a trocar and were of a peculiar grumous character, probably the result of hemorrhage into the interior of the cyst. There was but one cyst, and its collapsed wall was drawn through the abdominal wound with perfect ease. After securing the pedicle, the abdomen was closed with six interrupted sutures and the patient placed in bed. The tumor and its contents weighed thirty pounds. The temperature never rose ábove the normal, though the pulse for three days succeeding the operation varied from 120 to 140. After this time it gradually dropped to normal. The sutures were removed on the seventh day, and the patient left the hospital three weeks from the day of the operation. CASE LXXVIII.—Intra-ligamentary Cyst, Dissecting the Peritoneum in front as far as the Liver. Complete Enucleation of Cyst. Death.-Patient æt. 32. Referred to me by Dr. H. M. Warren of Jonesville, Michigan. Nationality, English; married. Entered the hospital on December 15, 1891. She began to menstruate at fourteen, at which time the menses were scant and recurred every two weeks, becoming regular at 21. Two years before entering the hospital she had typhoid fever, and for seven months following this attack she suffered from symptoms of malaria. Was married one year previously to consulting me. Two weeks before marriage she had a severe bearing-down pain in the uterus which continued after marriage. There was much pain in the bowels, with a feeling of distention. Had one miscarriage at the fourth month, which occurred in March. Flowed for ten days after the miscarriage. Had much leucorrhea, which was yellow and very excoriating. Had much pain around the left side of the body from the spinal column to the umbilicus. Appetite was poor and emaciation great; the bowels were regular. 734 A TEXT-BOOK OF GYNECOLOGY. - The abdomen was extremely enlarged and the ordinary symptoms of fluid confined within a cyst presented themselves. The operation was performed January 12, 1892. Upon exposing the cyst, instead of the smooth, glistening surface which is characteristic of ovarian cysts, its surface was very red and was covered with large vessels. The contents were fluid and readily passed through the tapping trocar. After the cyst was emptied it was found firmly fixed at its base. An incision was made into the capsule and the enucleation extended to the base of the broad ligament below and to the lower border of the liver above. There was much bleeding, which was controlled with difficulty by sponge packing and ligatures. I succeeded, however, in completely enucleating the cyst, when there was left behind an enormous cavity. The capsule was tied in sections and removed, its edges being brought together with continuous catgut sutures. A strip of gauze was placed in the lower end of the capsule and left projecting from the abdominal wound. Weight of cyst and contents, fifty pounds. Time of operation, two hours. The patient was removed from the operating table suffering greatly from shock. The temperature very soon began to rise, and on the following day it was evident that the gauze was not draining the cavity as it should. This was removed and a drainage tube inserted. The temperature gradually increased, prostration became more and more marked, and death occurred on the sixth day from sepsis. A subsequent exami- nation showed that the cavity left behind was not thoroughly drained. The mistake was, undoubtedly, in not stitching the emptied capsule to the abdominal wound and packing the cavity with gauze. I hoped to avoid the prolonged convalescence neces- sarily attending the healing by granulation. CASE LXXIX.-Large Proliferous Cyst Weighing Forty Pounds. Convalescence Uninterrupted.-Patient æt. 46. Referred to me by Dr. Byron Deffendorf of Fowler- ville, Michigan. Began to menstruate at seventeen; flow was normal and painless. Married at seventeen. Has had four children; labors all easy and natural. Had been troubled for a number of years with occasional severe attacks of pain in the stomach which seemed to be caused by indigestion. About four years before consulting me she noticed a growth in the left side which gradually increased in size. The menses were regular and painless but scant. Bowels were regular. The abdomen was enormously distended, and the pressure symptoms distressing. The abdomen was opened on February 20, 1891. The cyst was multilocular and proliferous. It was necessary to incise the cyst wall, introduce the hand, and break down the smaller cysts. The adhesions were not extensive and the collapsed cyst was withdrawn through the abdominal incision without difficulty. The left ovary had undergone cystic degeneration and was about as large as a hen's egg. This was re- moved, a drainage-tube introduced, and the abdomen closed by interrupted silk The temperature did not rise above the normal, and the patient left the hospital on March 12th, twenty days after the operation. sutures. CASE LXXX.-Large Fibro-cystic Tumor of the Ovary, with Long Pedicle, giving rise to Enormous Distention of the Abdomen from Ascitic Accumulation. Operation. Recovery.-Patient æt. 39. Referred to me by Dr. L. S. Morris of Lee's Corners, Michigan. Menstruated at 14; was not regular and has always had more or less dysmenorrhea. Married at 15. Has had seven children, the eldest being 21 and the OVARIOTOMY-ILLUSTRATIVE CASES. 735 youngest 8 years of age. The last labor was very severe, after which she had puer- peral fever, being confined to her bed for fifteen weeks. Five weeks following the last labor she noticed for the first time a tumor in the left lower abdomen. This con- tinued for about a year and then disappeared for two years. At the time of entering the hospital she complained of much pain in the vertex, and constant backache. The appetite was good. A physical examination revealed a large, solid tumor in the lower abdomen which was mobile and seemingly connected with the uterus. There was at the time of the first examination no ascites. The tumor caused much distress because of the pres- sure upon the rectum, giving rise to hemorrhoids and constipation. As immediate operative interference did not seem imperative, and as the University Hospital was about to close for the summer vacation, the patient was sent home to return in the fall. In the following October she reentered the hospital. The abdomen had, during the interval, increased greatly in size and the patient was much distressed in various ways. Upon examination there was found a large, solid tumor floating in fluid. It was entirely possible to practise abdominal ballottement. While lying upon the back, the tumor, if suddenly pressed downward, would float upward and strike the abdomen with a distinct choc en retour. It was surrounded by a tympanitic corona produced by the intestines floating upon the ascitic fluid. The diagnosis was somewhat uncertain. Owing to the large quantity of ascitic fluid I feared malignancy. The general health, however, did not indicate malignant degeneration. At any rate, it was very evident that an exploratory incision was neces- sary. This was made on October 28, 1892. The ascitic fluid at once escaped from the abdominal incision. A large fibro-cystic tumor of the ovary was found high up on the left side, almost in contact with the diaphragm. The pedicle was at least eight inches long. Owing to the great amount of solid matter in the tumor, it was necessary to extend the incision upward nearly to the sternum. The tumor was then removed with perfect ease and the pedicle tied and seared with the Paquelin. Cystic degenera- tion had begun in the opposite ovary, which was as large as the first, so this was also removed. The abdominal cavity was thoroughly washed with sterilized water and a drainage-tube introduced. The convalescence was uninterrupted, and the patient was discharged twenty-one days after the operation. The solid portion of the tumor weighed nineteen pounds. Operation. CASE LXXXI.-Parovarian Cyst Weighing Twenty Pounds. Recovery.-Patient æt. 33. Referred to me by Dr. A. Farnsworth of Saginaw, Mich- igan. Unmarried. When 11 years old she was seriously ill from getting her feet wet. Menstruation began at 15. Health good until six years ago, when she first noticed an enlargement low down in the pelvic region. She suffered no pain with this, except during the menstrual flow, which was profuse. Her appetite was good, she slept well, and had attended to her duties as postmistress up to the time of entering the hospital, October 23, 1890. On October 24th the abdomen was opened in the usual way. The cyst was found to be parovarian, the walls being very thin. It was partly intra-ligamentary, but was enucleated without serious difficulty. The tube and ovary were bound down by adhesions and were, therefore, removed. The folds of the capsule at its base were stitched together by a running catgut ligature and the tissues cut away above it. Owing to the free oozing from the surfaces of the capsule, the abdomen was washed 736 A TEXT-BOOK OF GYNECOLOGY. with sterilized water and a drainage-tube introduced. Time of operation thirty minutes. The drainage-tube was removed on the third day, after which the temperature ran up to 101°, and fluctuated between 100° and 102° for the succeeding six days. During this time Arsenicum iodide 3 x was administered. She was discharged on November 26th, and ultimately recovered her health perfectly. CASE LXXXII.—Exploratory Incision for Papillomatous Degeneration of Ovaries. Profuse Hemorrhage, which was Controlled by Extensive Gauze Packing.—Miss A., æt. 53, had suffered for years with symptoms of fibroid tumor, with profuse menorrhagia and metrorrhagia, which nearly terminated her life upon several occasions. I examined the patient some three years previously to the operation and found the pelvis packed with a hard, solid tumor intimately connected with the uterus and presenting all the characteristics of a fibroid. Two years previously to the operation the uterine hem- orrhages ceased and the patient had seemingly passed through the menopause. The enlargement within the pelvis remained quiescent for a year; then it suddenly began to increase in size and at the time of the exploratory operation the pressure symptoms were most distressing. It was utterly impossible to determine the charac- ter of the tumor by physical exploration. The uncertainties of the case were pre- sented to the patient and her friends and an exploratory incision was agreed upon. I was assisted by Prof. D. A. MacLachlan and Dr. Mary Denison. After incis- ing the peritoneum, a large quantity of ascitic fluid, tinged with blood, escaped. The finger was cautiously introduced; but notwithstanding the great care observed, most profuse and alarming hemorrhage set in. It was very evident that the patient would quickly succumb unless this was controlled. The incision was, therefore, enlarged above and below and the pelvis and lower abdomen were found completely filled with papillomatous growths. To have attempted to remove these would have been homi- cidal. Accordingly, I packed over and about the bleeding surfaces iodoform gauze— introducing in all four yards—leaving the end projecting from the lower angle of the wound. The abdominal incision above this was then quickly closed. The patient was removed from the table in a state of collapse, but by the energetic use of stimu- lants internally, per rectum, and hypodermatically, she rallied and lived for eight weeks. A portion of the gauze was removed on the third day, the remainder being left behind for four days longer. Of course, there was left a large cavity to fill in by granulation. This cavity was for the first six weeks kept perfectly sweet by irriga- tion through drainage tubes; but large portions of the papillomatous growths sloughed away, and in spite of every effort the patient succumbed at the end of two months from blood poisoning. This case illustrates most emphatically the utility of gauze packing in controlling hemorrhage. Without it I do not believe that the hemorrhage could have been con- trolled, and the patient undoubtedly would have bled to death on the table. CHAPTER XLVIII. INFLAMMATORY DISEASES OF The uterine APPENDAGES. General Considerations.-In the chapter dealing with acute inflammation of the uterus and periuterine tissue, I devoted a short space to the consideration of acute salpingitis and ovaritis. Acute inflammation of these organs was, however, considered rather in the light of a complication of general pelvic inflamma- tion than as a distinct pathological entity, and rightly so. When the pelvic contents are implicated in the general inflamma- tory attack the most deft diagnostician will be unable to deter- mine, in at least the larger number of instances, the extent of involvement of the ovaries and tubes. In the chapter referred to, I mentioned certain symptoms which, if present, would lead the student, in acute pelvic inflam- mation, to suspect the involvement of the ovaries and tubes (v. p. 417). These are: excessive tenderness in the region of the ovaries, pain, nausea, and vomiting. Additional evidence may be obtained in reasonably favorable cases by palpating the enlarged and tender ovary or ovaries, though I especially emphasized the necessity of care during physical exploration while acute inflam- mation of any of the pelvic organs exists. It remains for me, then, in the present chapter, to discuss the acute forms of in- flammation of the uterine annexa, not in detail, but to such an extent as will enable the student intelligently to comprehend those chronic forms of inflammation which are so frequently the sequelæ of acute inflammation. If the reader will refer to Fig. 173 he will obtain some idea of the intimate lymphatic connection existing between the uterus and its appendages. This illustration will enable him to under- stand why it is that the tubes and ovaries are so often secondarily involved in diseases of the uterus. The continuity of the mucous 47 737 738 A TEXT-BOOK OF GYNECOLOGY. membrane lining the uterus and the Fallopian tubes, and the close proximity of the ovaries to the fimbriated extremity of the tubes, are additional reasons why salpingitis and ovaritis so often follows in the train of metritis. Varieties. I shall adopt the classification of Pozzi, because it serves to indicate the various pathological changes which FIG. 173. LO 11 7 12 E BOULENAZ C.DEVY LYMPHATICS OF UTERUS. 1. Lymphatics coming from the body and fundus of uterus. 2. Ovary. 3. Vagina 4. Tube. 5. Lymphatics coming from the cervix. 6. Lymphatics to the iliac glands. 7. Lymphatics to the lumbar glands. 8. Anastomoses uniting the ves- sels of the cervix and of the body. 9. Small lymphatics in the round ligament to the inguinal glands. 10, 11. Lymphatics of the tubes. 12. Ovarian ligament (Poirer.) the appendages, when they become diseased, may take on. This classification is as follows:- I. Non-cystic salpingitis, II. Cystic salpingitis, a. Acute catarrhal; b. Acute purulent; c. Chronic parenchymatous (pachysalpingitis). Hypertrophic, or vege- tating variety; Atrophic, or sclerous vari- ety. a. Hydrosalpinx, or serous; b. Hematosalpinx, or hemorrhagic; c. Pyosalpinx, or purulent. INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 739 NON-CYSTIC OÖPHORO-SALPINGITIS. It will be observed that the term oöphoritis is excluded entirely from the foregoing classification. Inasmuch as marked salping- itis rarely, if ever, occurs without concomitant disease of the ovary, it is well to note at once that the use of the term salping- itis implies that both the tube and ovary are involved in the inflammatory process; that, indeed, an oöphoro-salpingitis is meant. Etiology.-Acute metritis and endometritis are the chief sources of the disease. It is maintained by Championnière that the propagation occurs, in all instances, through the lym- phatics. As proof of this, he cites the fact that, in at least the majority of cases, the uterine extremity of the tube is not in- volved, the external two-thirds being the part chiefly affected. Pozzi teaches that the indemnity is apparent only, for the micro- scope shows that the tissues of the inner third are markedly inflamed. While it will not do to ignore the rôle played by the lymphatics, especially during the puerperal state, it is probable that the disease, in the greater number of cases, extends from the uterus to the tubes by continuity of tissue. This is emphat- ically so in specific endometritis. The frequent association of metritis with salpingitis is often overlooked when the symptoms of the former overshadow those of salpingitis. An intense metritis may be associated with a slight salpingitis without the latter condition being known; and, conversely, if the disease is primarily located in the tubes or the ovaries the metritis may pass unrecognized-hence the possi- bility of failing to determine the simultaneous existence of the two affections. I have in another place * discussed gonorrhea as a causative factor of endometritis and pelvic inflammations in general. Tait maintains that the uterus and tubes may become infected by the gonorrheal virus without the preëxistence of distinct vaginitis. There can be no question that the significance of gonorrhea as a causative factor, has not yet received the attention which its *v. page 382. 740 A TEXT-BOOK OF GYNECOLOGY. importance warrants, though it is possible that an exaggerated significance has been given to it by Noeggerath. The fact that the gonococcus of Neisser is not always found in the pus taken from pus-tubes, by no means proves a non-gonorrheal source of infection. The next most frequent cause is puerperal infection. Mem- branes retained after abortion become septic, thus giving rise to metritis and succeeding salpingitis. Should, however, gonorrheal infection precede abortion or parturition, the real cause of the difficulty may be overlooked. The puerperal state, in instances of this kind, tends to propagate the gonorrheal virus, and un- doubtedly many cases of puerperal peritonitis and cellulitis are due to gonorrheal metritis with secondary involvement of the tubes, ovaries, and periuterine tissues. (Tait.) The other causes are those which may give rise, if operative, to metritis or general pelvic inflammation. They include the improper use of the sound, operations upon the cervix, un- skilful obstetric operations, and the want of proper surgical or obstetric cleanliness. Tubercular salpingitis is rarely met with as an idiopathic affec- tion. It is usually associated, when it occurs, with tubercular in- volvement of other abdominal and pelvic viscera. In those rare instances where it is met with as an isolated lesion, its probable origin is tuberculous spermatozoa which find their way into the tube. This explanation will not, however, apply when the affec- tion occurs in virgins. In such cases, according to Pozzi, the tubercle bacillus is first introduced into the circulation through the lungs or digestive tract, and finally lodges in the tube. The eruptive diseases-scarlatina, variola, etc.—are, according to Tait, frequently responsible for disease of the tubes and ovaries. This author, together with Freund, believes also that congenital malformations of the tubes with atrophy predispose to salpingitis. Symptoms. In subacute and chronic salpingitis and ovaritis, pain is an almost inseparable feature. It is, in at least nineteen cases out of twenty, worse on the left side; and, if unilateral, is almost certain to be located on the left side. (Tait.) It INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 741 is more or less persistent and is aggravated by walking or by jars of any kind. It extends down the thighs into the back and frequently involves, in a reflex way, the breast of the corres- ponding side. It is almost always intensified immediately before and during menstruation, giving rise to that form of dysmenor- rhea known as "ovarian." Occasionally the pain is great enough to prevent the patient from standing erect. Dyspareunia more or less marked is rarely absent. This is due to the fact that the inflamed ovary is nearly always prolapsed. A digital or bimanual examination will, if the ovary is pressed upon, give rise to a peculiar sickening sensation, which persists for some time after the pressure is removed. In rare instances the suffering is relieved by the onset of the menstrual flow. Menstruation is oftener excessive than deficient in quantity. This is due to the general pelvic congestion perpetuated by the disease, as well as to the fundal endometritis which is rarely, if ever, absent. When the ovaries become cirrhotic, partial or complete amenorrhea may ensue. The subjective symptoms alone are not sufficient for diag- nostic purposes, and, especially if an abdominal section is con- templated, a careful physical examination should be made under ether. Even then it is not possible to detect micro-cystic de- generation of the ovary or simple catarrhal salpingitis. In chronic salpingitis, if the conditions are favorable, the tube can be felt as a resisting, hard, tense cord. Differentiation.-The following affections will call for differ- entiation :- Metritis ; Lumbo-abdominal neuralgia; Ovaralgia. Metritis. It is unnecessary to repeat the special symptoms belonging to this affection. Indeed, when the tube is inflamed, traces of a preceding metritis usually exist. Should the symp- toms of metritis still preponderate, it is utterly impossible to determine with any degree of positiveness the extent of in- volvement of the tubes and the ovaries. If the inflammation is limited to the uterus the increased weight of the organ, together • 742 A TEXT-BOOK OF GYNECOLOGY. with its mobility, will at least suggest that the appendages are not seriously implicated. Lumbo-abdominal Neuralgia.—This is due, in the larger num- ber of instances, to some affection of the uterus. The pain is located in the abdominal wall and is made worse by superficial pressure. Ovaralgia.—Ovaralgia, or neuralgia of the ovaries, is not infrequently associated with inflammation. Nevertheless it often occurs as an idiopathic affection, if, indeed, it is right to speak of any neuralgia as “ idiopathic." The pain is usually con- fined to one side. It comes and goes in quick succession. The attacks are oftener met with in hysterical patients and in women who are victims of neuralgia in other parts of the body. There may be anesthesia of the corresponding part of the body. (Charcot.) Since inflammation of the tubes is nearly always associated with that of the ovaries, it is rarely possible to determine with any degree of precision, even after a most careful local examination has been made, which organ is chiefly affected. We are led to suspect that the ovary is chiefly involved when the tumor is oblong; when it is mobile and some distance from the uterus; when the sensitiveness is very great; and when dysmenorrhea is a marked symptom. Prognosis.-Chronic salpingitis and ovaritis, whatever may be the form of inflammation, is an exceedingly obstinate affec- tion. Owing to the fact that all of the pelvic organs are periodi- cally congested by the menstrual function, it is impossible to bring to the diseased appendages physiological rest so long as menstruation continues. The lining membrane of the tubes can- not be gotten at for treatment as can the endometrium. There is, too, a peculiar tendency for the tube to become occluded, both at its uterine and its ovarian extremity, so that the secretions are pent up. Nevertheless, relative cures may occur, even though pus is present, though in nearly all cases the tube remains more or less altered after an acute attack of salpingitis. Sterility is a frequent sequela, though not an absolute one if the disease does not involve the appendages of both sides. The symptoms are, in nearly all instances, most persistent, and attacks of peritonitis INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 743 are of frequent occurrence. These attacks are supposed to be due to a few drops of muco-pus escaping from the tube into the peritoneal cavity, or to irritating fluid escaping from ruptured ovarian follicles. CYSTIC OÖPHORO-SALPINGITIS. Of the three forms of cystic salpingitis pyosalpinx is the most frequent. This, it is claimed, may be transformed into hydro- and hemato-salpinx. The method by which this is brought about is somewhat uncertain. It is probable that the germs are spontaneously destroyed and the inflammatory process arrested, when the pus undergoes a species of clarification and is con- verted into serous fluid. This at least is the explanation of Pozzi, who believes that the great majority of cases of hydrosalpinx originate in this way. A hematosalpinx may result from the rupture of the vessels in the walls of a pyosalpinx, the sac be- coming filled with blood. A more frequent cause of hematosal- pinx is Fallopian pregnancy, the ovum dying after rupture and the tube remaining distended with blood. It may also be asso- ciated with hematometra, due to obstruction within the cervix or vagina. Hydrosalpinx.-Tubal dropsy rarely attains a very large size. It is not improbable that the large tubal cysts reported by the older authorities were in reality distended tubes connected with true ovarian cysts. They may, however, attain a size equal to that of a fetal head. (Figs. 174 and 177.) The walls of the cyst are thin and present a bluish white color. Hematosalpinx.-The tumor produced by true hematosalpinx is usually not larger than the fist. The contents consist of a mixture of blood and pus, or of blood and serum. It is neces- sary to exclude from the category of hematosalpinx those slight effusions of blood due to inflammation of the walls of the tube which are susceptible of spontaneous reabsorption. Pyosalpinx.-Purulent cysts of the tubes and ovaries vary in size from that of a small pear to that of a fetal head. The sac is also of variable thickness. The pus presents a creamy yellow appearance and is often most offensive, especially if it communi- cates with the bowel. Not infrequently the ovary contains dis- 744 A TEXT-BOOK OF GYNECOLOGY. seminated abscesses; or it may be so intimately attached to the fimbriated extremity of the tube as to become an integral part of the cyst. (Figs. 175 and 176.) Symptoms. Grouping the three forms of cystic enlarge- ment of the tubes and ovaries under one head, is in entire har- mony with clinical facts. That is to say, so far as both subjective phenomena and local symptoms are concerned, it is usually im- FIG. 174. HYDROSALPINX. A dilated left tube which weighed, inclusive of its fluid contents, 1 lb, 6 oz. From a single woman, aged 23. The right Fallopian tube weighed, including its contents, 4 lb, II oz. (Museum R. C. S. Photographed by the Author.) possible to differentiate the three affections from one another. It is true that during the acute period of pyosalpinx the symp- toms are more intense and the usual systemic disturbances attend- ing the formation of pus in any part of the body may present themselves. In due time, however, the pus within the tube usually becomes latent and, if the encystment is complete, the system will tolerate its presence without any constitutional disturbance. INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 745 Should the tube rupture, or the pus escape through the fimbri- ated extremity into the peritoneal cavity, inflammation is more apt to result than when the fluid from a hydrosalpinx escapes into the pelvis. The frequent recurrence of chills and fever, given by the older authors as conclusive evidence of pyosalpinx, does not in fact take place even in the larger number of cases. I have repeatedly found pus within the tubes when the most FIG. 175. TUBO-OVARIAN CYST. A uterus with its appendages. Both Fallopian tubes are much dilated, especially the right. This has formed a communication with the corresponding ovary, which is dilated into a cyst over two inches in diameter. There are numerous adhesions on the surface of the uterus, the result of chronic peritonitis. (Museum R. C. S. Photographed by the Author.) careful cross-questioning failed to elicit any of the supposed classical signs of pyosalpinx. Pozzi refers to another symptom of cystic oöphoro-salpingitis the value of which, he maintains, has been much exaggerated, namely, the sudden escape of sanguineous, purulent, or serous fluid from the cervix, which may be frequently repeated. This author believes that in at least the larger number of cases pre- 746 A TEXT-BOOK OF GYNECOLOGY. senting such a history the fluid does not proceed from the tube but rather from the uterine cavity, and that it is due to an endometritis associated with more or less cervical stenosis. In support of this view he cites the fact that cystic tubes are usually obliterated at their uterine extremity. He nevertheless admits that it is sometimes possible to force the contents of distended tubes through the uterus and into the vagina by bimanual pressure. FIG. 176. TUBO-OVARIAN CYST. The uterine half of the tube is much elongated, thick-walled, and tortuous; it has been laid open and lies posteriorly. The outer half of the tube is extremely dilated. Masses of papillomatous growths spring from the mucous membrane of the tube. The ovary, which is seen below, forms a large single cyst which does not communicate with the interior of the dilated tube. (Museum R. C. S. Photographed by the Author.) The symptoms of hydrosalpinx are not usually so marked as those of the other two varieties of cystic disease. The amount of blood contained in a hematosalpinx is not ordinarily great enough to produce serious constitutional dis- turbance. INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 747 The general symptoms of the three forms of cystic disease are those of pelvic peritonitis with which all are so often associated. In all, pain will draw attention to the appendages. Upon physi- cal examination a tumor will be found on one, or, if bilateral, on both sides of the uterus. Care must be observed in practising the bimanual not to rupture the cyst.* FIG. 177. T' DOUBLE HYDROSALPINX. (Beigel.) T, right tube with abdominal mouth closed; o, right ovary; T', left hydrosalpinx; o', left ovary degenerated into a cyst. If the appendages of both sides are involved, the uterus is always more or less fixed. Usually the distended tubes will be found in * In a case brought to me by Dr. W. I. Tyler of Niles, Mich., a local examination revealed what seemed to be cystic distention of the right ovary and tube, the tumor being as large as a small orange. In making the bimanual under ether, I was not a little startled to have the cyst collapse between my fingers, evidently the result of rupture. The patient was placed in bed, every precaution taken to guard against peritonitis, and I held myself in readiness to make an abdominal section should the symptoms indicate the escape of pus into the peritoneal cavity. The cyst evidently contained innocent fluid, for no disturbance followed its rupture. 748 A TEXT-BOOK OF GYNECOLOGY. the cul-de-sac, where they are adhered; or, they may be so embed- ded in inflammatory|exudates as to be indistinguishable from the general contents of the pelvis. Local examination always gives rise to more or less pain. It is rarely if ever, possible to detect fluctuation, unless a large distended tube is adhered in the cul- de-sac and pushes the uterus forward. Not infrequently in pyo- salpinx the adhesions to the contiguous parts are so intimate that the tube loses its identity and cannot be enucleated. The subperitoneal tissues may become involved in the suppurative process, when the condition is converted into a true pelvic abscess. Differentiation.—It is, then, by no means possible to determine at the bedside which of the three forms of tubal disease exists, nor, from the standpoint of treatment, is the uncertainty of differentia- tion very important. Whether the tube contains pus, blood, or serum, if the distention is at all marked, operative interference is called for. Lawson Tait goes so far as to say that a classification of these cysts, based even upon the character of the fluid which they contain, is thoroughly impracticable. From the standpoint of prognosis, on the other hand, it is important to determine the probable character of the fluid which distends the cyst. All authorities agree that purulent pyosalpinx is more dangerous than hemato- or hydrosalpinx. This is be- cause of the intense peritonitis which usually results from the escape of pus into the pelvic cavity. A gonorrheal history, or a history of sepsis associated with parturition or abortion, will lead us to suspect that the tube is distended with pus. Unfortunately, it is by no means always possible, as we have seen, to obtain a history of gonorrhea, even though the source of infection be of this origin. Other conditions suggesting pyosalpinx are: the presence of extensive adhesions, frequent repetitions of pelvic inflammation, and, possibly, the occurrence of erratic chills, such as suggest pus in other parts of the body. It will not do, however, as I have already intimated, to eliminate pyosalpinx because this last symptom is wanting. Both hydro- and pyosalpinx are nearly always bilateral, whereas hematosalpinx is frequently confined to one side only. INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 749 This last fact suggests that Fallopian pregnancy is often respon- sible for blood cysts. Hydrosalpinx gives rise to adhesions much less often than do the other forms of tubal distention. The bimanual is also less painful when the cyst contains serum only. Zweifel* makes the following observation regarding pyosal- pinx: "In cases in which streptococcus and kapselcoccus were found there was often every evening marked remittent fever. In cases of tubercular pyosalpinx the fever rose from time to time; wherein it differs from gonorrheal pyosalpinx in which there was usually no fever at all when the patient was lying quietly in bed. If disturbed by the examination, the temperature rose at once and shortly after fell. In no case of gonorrheal pyosal- pinx was there swelling of the inguinal glands, while in pyogenic cases swelling was the rule." Cystic oöphoro-salpingitis may be confounded with- Uterine fibroids; Fibro-cystic tumors of the uterus ; Small ovarian cysts; Early tubal pregnancy ; Intraligamentous cysts. Uterine Fibroids.-There is an entire absence of fluctuation; the uterus is mobile; the depth of the cavity is increased; and the tumor is intimately blended with the uterus, except in pedunculated subserous fibroids. Fibro-cystic Tumors of the Uterus.-The difficulties of differ- entiation are sometimes very great. The size of the uterus is usually increased; the pain is not so marked; and in most cases the inflammatory history is wanting. Small Ovarian Cysts.-The tumor is more remote from the uterus; there is an absence of tenderness; and no history of pelvic inflammation can be obtained. Early Tubal Pregnancy.-The uncertainty previously to the period of rupture is very great. The increase in the size of the uterus is usually more marked than is the case with tubal disease. The ordinary symptoms of pregnancy-suppression * Annual of Universal Medical Sciences, 1892. 750 A TEXT-BOOK OF GYNECOLOGY. of the menses, changes in the breasts, etc.—may exist. The ir- regular spasmodic pain associated with tubal pregnancy is very much like the pain incident to cystic tubal disease. Intraligamentous Cysts.-These dissect the folds of the broad ligament so that they are in intimate contact with the uterus. There is an absence of inflammatory symptoms. Two most curious and interesting cases are cited by Doleris* of adherent enterocele in the cul-de-sac of Douglas, in which the conditions simulated very closely an inflammatory tumor of the appendages. The diagnosis was made only after the abdo- men was opened. THE PATHOLOGY OF NON-CYSTIC AND CYSTIC DISEASES OF THE UTERINE APPENDAGES. In simple catarrhal salpingitis (acute and subacute) the secre- tion is increased and there is more or less swelling and redness of the mucous membrane. There may also be shedding of the epithelium, wholly or in part, with thickening of the villi. The infiltration of the tube wall is usually very slight, though the swelling is sometimes great enough to be detected upon bimanual examination. In purulent salpingitis (acute and subacute) there is often found a pus-forming organism such as the streptococcus or kapsel- coccus. This may result either from sepsis following abortion, or labor at term, or from gonorrhea. The folds of mucous membrane are often increased, and frequently there are formed small pus cavities, or cysts of like character. (Chrobak.) In pachysalpingitis (chronic parenchymatous) there is excessive development of the tube wall due to increase of the connective tissue rather than to hypertrophy of the muscular. The mucous membrane is usually involved to a greater or less extent, its folds being hypertrophied. Vegetations not infrequently spring from the surface of the mucous membrane. In cystic distention of the tube, which is frequently preceded by one of the non-cystic forms of salpingitis, there is agglutina- tion of both the uterine and the fimbriated extremity of the tube. * Pozzi, "A System of Gynecology," p. 389. INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 751 The dilatation is oftener located at its external two-thirds, though it may involve its whole length. The pavilion attaches itself very often to the ovary, which may become fused with the cyst. Adhesions may attach the appendages to any part or organ of the pelvis, but oftener to the Douglas cul-de-sac. A suppurat- ing cyst of the broad ligament or ovary may communicate with the tube. Microscopically, ramifying vegetations are found pro- jecting from the lining membrane of the tube. Its walls are infiltrated with embryonic cells. All of the vessels are markedly dilated. If the ovary is the seat of chronic inflammation, it may localize itself largely, either in the follicles of the gland or in its fibrous tissue. In the first instance there is an increase in the number of follicles, resulting, according to Tait, from hyperemia. Instead of a general involvement of the follicles the follicular hypertrophy may confine itself to a few only, which condition constitutes a variety of cystic degeneration. (Rokitansky.) This form of cystic degeneration frequently gives rise to great suffer- ing and most profuse menorrhagia. Fibrous hyperplasia may be the most characteristic feature of ovarian inflammation. Here there is destruction of the follicles and an arrest of the development of the proper ovarian cells. Secondary contraction follows the hyperplasia and gives rise to so-called cirrhotic degeneration. This is nearly always attended with dysmenorrhea of a most serious character. In time it gives rise to amenorrhea more or less absolute. * In still another condition there may be great enlargement of the ovary due to hypertrophy of both the follicular and the fibrous elements of the gland, the relative proportions of the two structures remaining normal. Tait observes that the tubes are nearly always hypertrophied with the ovary. He says: "I have removed ovaries for intractable pain and hemorrhage which weighed as much as ten hundred and twelve grains, yet the most careful and minute examination of the organ revealed nothing more than an absolutely normal structure." The ovary may be destroyed by the processes of suppuration. * Op. cit. p. 430. 752 A TEXT-BOOK OF GYNECOLOGY. An abscess of the ovary unassociated with disease of the tube is, however, an exceedingly rare condition. The pus may be dis- seminated throughout the ovary, or one large abscess may occupy the center of the organ. In one of my cases the ovary was a mere shell and contained three ounces of pus. Progress and Termination: Prognosis.-In the various forms of non-cystic inflammation of the tube a relative cure is en- tirely possible. Undoubtedly too many tubes and ovaries have been sacrificed by enthusiastic laparotomists. Whether or not an absolute cure can be brought about after the tubes undergo interstitial changes, even by the most careful and skilful treat- ment, is very doubtful. It is, however, usually possible to make the patient very comfortable, even though such changes are the result of gonorrheal inflammation. Unfortunately cases are every now and then met with where, although no cystic distention exists, the dysmenorrhea and menorrhagia, as well as the general suf- fering, are such as to make salpingoo-öphorectomy the only resource. This should not be resorted to until all ordinary measures have been exhausted. Life is not endangered as it is in pyosalpinx, for in the latter affection rupture is liable at any time to occur and cause fatal peritonitis. I think it can be safely said that with the means now at our command, ablation of the appendages is unnecessary in at least ninety per cent. of all cases of non-cystic salpingo-oöphoritis. The duration of the affection is often prolonged and the physi- cian has to contend with the periodical congestion incident to menstruation. Nevertheless, a healthy conservatism has sprung up during the last few years and the specialists are resorting to salpingo-oophorectomy much less frequently than in the past. The curability of cystic accumulations is quite another matter. A woman is not for a moment safe while carrying within her pelvis a distended tube. In the first place, it is utterly impossible, as we have seen, to determine the exact character of the fluid within the cyst previously to its removal. Attacks of inflamma- tion are of frequent occurrence, and should rupture take place serious and even fatal peritonitis may be excited. In fact, these accumulations are rarely if ever cured spontaneously, though occasionally adhesions form between the rectum and the vagina, INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 753 through which their contents may escape. Unfortunately, an abscess opening into either of these cavities, especially into the rectum, usually continues to discharge indefinitely, giving rise to tenesmus, shooting pains, diarrhea, etc. I have recently had under observation a case of this kind, coming to me from the hands of an ultra "conservative" physician, where intermittent discharges of pus from the bowels took place every three or four months for five or six years, the patient finally succumbing to the disease. Occasionally the contents escape externally. The suffering in the cystic distention is frequently very great, and this in itself calls for radical measures. The pain is due to plastic adhesions and to distortion of the pelvic viscera which result from the frequent attacks of inflammation. The menstrual symptoms, particularly dysmenorrhea and menorrhagia, are usually marked. When the ovarian stroma is entirely destroyed menstruation may cease entirely. 48 CHAPTER XLIX. INFLAMMATORY DISEASES OF THE UTERINE APPENDAGES-(Continued). TREATMENT OF NON-CYSTIC AND CYSTIC OÕPHORO-SALPINGITIS. The conservative treatment of inflammation of the Fallopian tubes and ovaries is applicable to the non-cystic forms only. In that large class of affections so frequently met with, where en- dometritis or metritis has extended beyond the uterus and has implicated the appendages, conservatism is eminently proper, for much relief may be afforded and a relative cure accomplished in a goodly per cent. of cases. The principles of treatment applic- able to these affections do not differ essentially from the treat- ment of general pelvic inflammation. Rest, especially during and just before the menstrual periods, is of the first importance. The hot douche administered in such a way as to bring into action its thermic properties is invaluable; it may be advan- tageously supplemented by the hot bath, or by sea-bathing. Uterine drainage should be secured and the proper medicaments applied to the endometrium. Electricity is, I am convinced, an agent of inestimable value in contending with non-cystic tubal disease. My method of applying it is to localize the galvanic current within the pelvis by passing a suitable electrode into the uterus and a large dispersing pad over the abdomen. In this way a current of from twenty to forty milliampères should be used for from five to ten minutes at each séance, and repeated twice or three times a week. Medicated tampons of cotton wool should be inserted after any form of local treatment. Finally, a carefully selected remedy should be administered. I desire to emphasize the necessity of patience and persis- tence in carrying out the line of treatment indicated in the foregoing. There are so many factors to contend against, that the physician will be disappointed if he expects to accomplish a cure in a few weeks' time. Of this fact the patient should 754 INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 755 be apprised. With a possible abdominal section confronting her, she is usually most willing to coöperate with her physician in carrying out any kind of conservative treatment. Unless the suffering is very great, and the symptoms most urgent, I do not believe that we are justified in resorting to laparotomy in non- cystic tubal affections without at least a six months' trial of con- servative treatment. In dealing with the cystic diseases, on the other hand, blind conservatism is most reprehensible. A woman who has a dis- tended Fallopian tube, and who suffers from frequent attacks of peritonitis, can have no greater misfortune come to her than to fall into the hands of a physician incapable of comprehending the dangers which beset his patient. The medical attendant advises against an operation and the case progresses from bad to worse until finally a point is reached where an operation, if done at all, must be done when she is practically moribund. Salpingo-oophorectomy, under favorable circumstances, is not a dangerous operation. If, however, the patient is suffering from acute peritonitis, the result of rupture, if her strength has been depreciated by long continued suffering, if, in short, the operation is done as a last resort," the circumstances are very different. The abdominal surgeon who does his full duty will save a certain per cent. of these neglected cases, but his mortality record will suffer accordingly. Salpingo-oophorectomy for Inflammation of the Append- ages.-Salpingo-oophorectomy, when performed for the inflam- matory diseases of the tubes and ovaries, may be a very easy or a very difficult operation. It is usually more difficult than is an ordinary ovariotomy. The reasons for this are, that the abdom- inal walls are not stretched by the presence of a large tumor, and associated with the disease of the appendages there are usually extensive adhesions which distort all of the pelvic organs. The preparatory treatment does not differ from that recom- mended in Chapter XII. The waterproof sheet is unneces- sary. The incision is made in the middle line, extending from about two and a half inches above the pubes to three inches below the umbilicus; an incision of from two to three inches in 756 A TEXT-BOOK OF GYNECOLOGY. length will ordinarily afford sufficient room. Upon opening the peritoneum the omentum and intestines are, if not adherent, pushed forward, and the surgeon passes the two fingers of his right or left hand downward toward the fundus uteri. The fun- dus will serve as a guide for future operations. The extent of the adhesions is most variable. The omentum is not infrequently attached to the bladder, intestines, or uterus; when this is the case, these adhesions should be first detached. The omentum may also attach itself to the tube and ovary, which are sometimes lifted from the pelvis by it. In dealing with omental adhesions which cannot be separated in the ordinary way, it is best to cut them between two pairs of catch-forceps; later, a ligature can be applied to their proximal end. The surgeon next explores the appendages by passing the fingers of his right hand over the fundus of the uterus along the broad ligament and Fallopian tube on either side. Not infrequently the distortion is so great as to make it exceedingly difficult to distinguish the various pelvic structures and organs from one another. Usu- ally, however, the fundus of the uterus will afford a land- mark by which the surgeon can locate the tubes. It may be that the ovary and tube, though diseased, are easily drawn up through the abdominal wound. If so, they are secured in a Staffordshire knot and cut away. It is best to leave the ligature long until the opposite appendages are secured. In other in- stances, perhaps the majority, the tube and ovary are firmly fixed deep in the pelvic cavity, the most frequent site of the adhesions. being the cul-de-sac of Douglas. A great deal of force may be required to free appendages thus adhered. If the operation is once undertaken, there are very few instances where it ought to be abandoned. A possible exception to this rule occurs in those cases where the adhesions are universal, and where the patient's condition will not warrant extensive intra- abdominal manipulations. If it is possible, in these cases, to open the tube and drain it through the abdominal wound, it may be wise to proceed in this way. However, Lawson Tait has taught the profession that, unless the circumstances just enum- erated exist, incomplete salpingo-oophorectomy ought rarely, if ever, to occur. I have seen this operator remove the appendages INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 757 when it was absolutely necessary for him to tear by sheer force the large sacs from the pelvic cavity. I have taken much greater chances in desperate cases since seeing him operate. In dealing with adhesions deep in the pelvis it is best to de- pend entirely upon the sense of touch. After determining the actual limits of the diseased organs, they are gradually unfolded from below until a pedicle is formed. Even after they are un- folded in this way, the tube and ovary cannot always be brought out of the abdominal wound, for the changes within the broad ligament may leave them so unyielding as to make this impos- sible. It is here necessary to enlarge the abdominal wound and secure the ovary and tube within the abdomen in one or more ligatures. Tait, in these cases, carries his finger down to the pelvic insertion of the broad ligament and causes a series of minute tears at this point through the peritoneum and fibrous fascia. This leaves the ligament elastic and distensible without endangering the vessels running through it. The hemorrhage following the separation of extensive adhe- sions is sometimes very great and it should be temporarily con- trolled by sponge packing.. After the appendages are removed, if the hemorrhage still persists, a solution of iodin may be applied to the bleeding surfaces, or the parts may be seared over with the Pacquelin cautery. Any spurting arteries are, of course, secured by forcipressure, or by ligatures. It may even be ne- cessary to leave several pairs of forceps attached to the bleeding points for some hours after the operation. Usually, however, if the hemorrhage is simple oozing, it can be controlled by sponge packing. In dealing with distended tubes, especially if the contents are purulent, care should be taken not to permit the pus to escape into the peritoneal cavity. If there is danger of rupture it is best to evacuate the tube with an aspirator and close the open- ing thus made by pressure forceps. If pus escapes into the peri- toneal cavity, or if the oozing is very profuse, irrigation with hot sterilized water should always be resorted to. It is my practice in these cases to leave the abdomen distended with water. When extensive adhesions have been separated, and especially if the 758 A TEXT-BOOK OF GYNECOLOGY. peritoneum has been contaminated by pus, a drainage tube is imperative. It is nearly always necessary to remove the appendages of both sides although the disease may be very much more exten- sive on one side than on the other. Tait especially emphasizes the importance of this practice. Even though the disease of the opposite side is not extensive it is very liable to become so after the first operation. If, however, the patient is especially anxious to have the appendages of one side conserved, her wish should receive due consideration, though the probabilities of a second operation should be presented to her. The after treatment of salpingo-oophorectomy does not differ from the after treatment of laparotomies in general. Illustrative Cases. CASE LXXXIII.—Pyosalpinx, the Result of Gonorrheal Infection. Oöphoro-sal- pingotomy, followed by Intestinal Obstruction. Reopening of the Abdomen at the end of Forty-eight Hours. Recovery.—Patient, American, æt. 24. Referred to me by my former assistant Dr. C. M. Thurston of New Castle, Indiana. Married for five years. Entered the hospital November 7, 1892. Menses came on at the age of twelve and she has not been well since. The menses have always been irregular, too profuse and very painful. The pain during menstruation is located in the uterus and ovaries; indeed, there is constant soreness and suffering in both of these regions. There is a history of gon- orrheal infection four years ago, since which time she has been very much worse in every respect. Following this attack she was for a long time very low with pelvic in- flammation. Attacks of pelvic peritonitis since then have been very frequent. She has been compelled to leave her husband because of excessive venery. Menstruation is now very profuse and each period leaves her greatly exhausted. There is more or less increase of temperature during the periods. Appetite good; bowels constipated. The urine is either scanty and high colored, or light colored and profuse. It contains small quantities of albumin, pavement epithelium, a few crystals of oxalate of lime, red blood cells and pus. The albumin is no more than can be accounted for by the presence of pus. A physical examination shows very great tenderness of all of the pelvic organs, with retroversion of the uterus and fixation. An ill-defined mass is distinguished at the left of the uterus but gives rise to no evidences of fluctuation. Because of the excessive pain, the dyspareunia, and the intractable uterine hemor- rhage, laparotomy was recommended. The abdomen was accordingly opened on November 24th, 1892. The adhesions of the omentum to the uterus and left tube were very firm and had to be cut. The pelvis was filled with inflammatory exudates, the result of the frequent attacks of peritonitis. It was, however, possible to distinguish the fundus of the uterus by carrying the finger along the left broad ligament. The corresponding tube was found distended with pus and firmly fixed in the cul-de-sac of Douglas. The ovary was implicated in the suppurative process, constituting a true INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 759 tubo-ovarian cyst. It required a great deal of force to peel the cyst from the posterior layer of the broad ligament and from the cul-de-sac. However, I finally succeeded in doing this by first securing the tube at its uterine extremity and afterward tying in sec- tions the broad ligament at the pelvic extremity of the tube. The tumor was filled with inspissated pus in which no gonococci were found. The left tube and ovary, though not greatly enlarged, were firmly adherent and were removed. The right ovary showed well-marked hyaline and cystic degenerative changes. There was left behind, after removing the cyst, a large bleeding surface which con- tinued to ooze in spite of sponge pressure and the application of iodin. I therefore packed this surface with iodoform gauze, leaving one end projecting from the lower extremity of the wound. This was the only form of drainage used. The patient rallied from the operation, but twenty-four hours later began to develop symptoms of intestinal obstruction. These became more marked until the end of the second day, when it was clearly evident that the only way to save her life would be to re-open the abdomen. This was done forty-eight hours after the first operation. A knuckle of intestine was found attached to the site of the adhesions, which was the cause of the obstruction. The intestines were enormously distended with gas, and immediately upon re-opening the wound forced themselves from it. They were punctured in numerous places with a fine hypodermic needle in order to permit the gas to escape; the abdomen was then washed with sterilized water, a glass drainage tube inserted, and the abdominal wound reclosed. It was with great difficulty that the intestines were returned to the abdominal cavity. The vomiting soon ceased, the temperature dropped to normal, flatus began to pass per anum, and from this time on the patient made an uninterrupted recovery. She reports herself, one year later, in perfect health. I am sure that, had the second operation not been done, she would have died from the intestinal obstruction. CASE LXXXIV.-Pyosalpinx of Right Side with Cystic Degeneration of the Ovaries. Retroflexion of the Uterus. Salpingo-oophorectomy and Hysterorrhaphy. Recovery.— Patient, æt. 28; referred to me by Dr. G. D. Green of Mason, Michigan. Married, and has had two children, both being dead. She entered the hospital December 1, 1891, and gave the following history: Mother suffered more or less from lung trouble. Father died of phthisis two years ago. Has one brother with weak lungs. When young she was the picture of health. Began to menstruate at sixteen; the function has always been irregular, occurring every two or three weeks. Menses too profuse, the discharge being dark and often clotted. There has always been, too, a dysmenor- rhea of a most marked character. The pain is in the uterine region, appearing before, and continuing during, the flow. It extends to the back and is of a most excru- ciating character. Has a profuse, excoriating leucorrhea between the menses, which compels her to wear a napkin during the entire interval. Her first child was born six years ago, labor lasting about ten hours. Was in bed for fourteen or fifteen days, and did not get up well. The second birth was prema- ture, occurring two years ago. Soon after the last confinement she had a severe attack of peritonitis, the result of a fall, since which time there has been almost constant pain in the right side, extending down the inner side of the corresponding limb to the middle of the thigh. This pain is very intense and deep-seated. She is now compelled to keep her bed during the entire menstrual period. The menstrual pains are labor- 760 A TEXT-BOOK OF GYNECOLOGY. like in character, gradually growing worse as the period advances, and continuing for some days after the flow ceases. Headache is almost constant, and is worse after menstruation; it is located at the base of the brain and forehead. Appetite is poor particularly during menstruation. A bimanual under ether showed the fundus of the uterus retro-displaced, but it could be lifted out of the hollow of the sacrum. The products of inflammation were clearly outlined in the right broad ligament. The tube of that side was enlarged and evidently distended. Both ovaries were enlarged to at least three times their normal size. The abdomen was opened on December 12, 1891. The right ovary and tube were firmly adhered and were removed with some difficulty. The left tube was not en- larged, but the ovary was clearly diseased and the appendages of that side were accordingly removed. The fundus was stitched to the anterior abdominal wall by means of two silk sutures. The intervening peritoneum was irritated with the point of a scalpel for the purpose of exciting adhesions. The abdomen was closed in the usual way without drainage. An examination of the appendages after their removal showed the right tube distended with pus; both ovaries had undergone cystic degeneration. The patient convalesced with hardly a bad symptom. The abdominal sutures were removed on the seventh day, those passed through the uterus being left behind for three days longer. She returned home four weeks from the time of the operation and is now (eighteen months later), except for the flushes of heat which still distress her more or less, perfectly well. Case LXXXV.-Hydrosalpinx of Right Side with Cystic Degeneration of Corre- sponding Ovary. Interstitial Salpingitis of Left Side with Cirrhotic Degeneration of Left Ovary. Salpingo-oöphorectomy. Recovery.-Patient, æt. 34; referred to me by Dr. E. A. Lodge of Milford, Michigan. She entered the hospital October 10, 1891, and gave the following history: Was very healthy until menses occurred. at fourteen, since which time she has never been well. Suffered from intense neuralgia of the head from fourteen to twenty. Menses always lasted from five to seven days, recurring about every twenty-four days. Was married at twenty-four, and has never been pregnant. The uterus has been displaced to the right and backward for several years. During menstruation she suffers from a most excruciating pain in the ovarian region which completely pros- trates her. There is much tenderness over the lower abdomen at this time with a slight increase of temperature. There is, in addition to the foregoing, a flatulent dyspepsia which is always aggra- vated at the menstrual period. She suffers a great deal from pain which begins in the back of the neck and extends up to the temples through the head. last year there has been almost constant pain in the small of the back. is not marked. During the Leucorrhea The bimanual revealed an unusually large vagina for a woman who had never had children. There was an ill-defined thickening on the right side, and on the left there was evidently a distention of the tube. Physical examination caused much pain. The abdomen was opened October 13, 1891. The uterus was found drawn to the right by the inflammatory exudates of that side. The left tube was distended with serum, and the right was greatly thickened as a result of interstitial salpingitis. The INFLAMMATORY DISEASES OF UTERINE APPENDAGES. 761 right ovary was enlarged and cystically degenerated. The left had undergone atrophy and was not larger than a Lima-bean. Both appendages were removed without serious difficulty and the abdomen closed in the usual way. The convalescence was interrupted on the seventh day by the patient eating freely of honey which was surreptitiously conveyed to her. This gave rise to severe enteritis with peritonitis, which nearly terminated fatally. She recovered from this attack, however, and was permitted to sit up on November 1st. On November 3d she walked across the room, and a week later left the hospital for her home. She is now quite well. CASE LXXXVI.-Oöphoritis of Twenty Years' Standing. Complete Prostration from Neurasthenia. Salpingo-oophorectomy. Recovery.—Patient æt. 32; unmarried; referred to me by Dr. A. B. Spinney of Detroit, Michigan. Her mother died of gastric fever. Father is well, aged 68. One brother living; strong and well. One sister living, not in good health. When she was about fourteen years old she fell and struck the small of her back. When sixteen had sharp neuralgic pain in the left ovarian region, made worse by being on her feet. Was compelled to leave school at seventeen. Began to menstruate at fourteen; has always suffered greatly from dysmen- orrhea, the flow being too long and too profuse. The pain comes on a day or two before the flow and continues during it. Her mother died ten years ago, after a six weeks' illness, during which the patient had practically the entire care of her, especially at night. After her mother's death she was bedridden for two years, during which time the ovarian pain was greatly ag- gravated. She placed herself under the care of a physician who resorted to local treatment, which consisted largely of applications of nitrate of silver to the cervix. At the end of two years she was able to get up and about, though the pain in the ovarian region was still more or less persistent. Two years ago she fell on the ice, again in- juring her back. To use her own expression, "the backbone felt as though it were driven through the head." A week later the ovarian distress became intensified and there was swelling and tenderness of the corresponding side. The temperature was increased and nausea and vomiting were marked symptoms. She was confined to her bed for five months. Spinal irritation has been a marked symptom for the last two years, during which time she has been bedridden. A physical examination showed enlargement of the right ovary with very great tenderness. There is endome- tritis with a small mucous polypus projecting from the cervical canal. Neurasthenia is most profound. Local galvanism was applied to the ovary and to the spine. The only additional local treatment consisted of hot douches administered twice a day. Cimicifuga and bryonia were given internally and every means taken to improve the patient's nutrition. She, however, made but little progress under this treatment and an abdominal section was decided upon. The abdomen was opened on December 4, 1888. The right ovary was at least four times its normal size and the tube greatly thickened. The fimbriated extremity of the tube was adhered to the ovary. The left tube and ovary were likewise impli- cated in the inflammatory process, though to a less extent. It was, however, deemed best to remove the appendages of both sides. The abdomen was closed in the usual way. A slight attack of peritonitis followed the operation, the temperature rising on the 762 A TEXT-BOOK OF GYNECOLOGY. following day to 102°. This subsided and the sutures were removed on the seventh day. She regained her health somewhat slowly, but was able to leave the hospital on February 9th. Three years later, while coming from Detroit to Ann Arbor, I was approached by a lady who introduced herself as this patient. The change was so great that I did not recognize her. She had taken on flesh and was, indeed, the picture of health. She steadily gained after returning home, is now supporting herself by teaching school, and is in every way perfectly well. I have selected from my series of cases of inflammation of the appendages the foregoing, as typically illustrating the benefit to be derived from salpingo-oophorectomy when the operation is indicated. In the chapter devoted to hystero-neuroses I have referred to several additional cases in which salpingo-oöpho- rectomy was done for various nervous troubles. It is not neces- sary at this time to introduce further evidence illustrating the utility of the operation under proper circumstances. I will sim- ply add that, especially if done for nervous lesions, discrimina- tion should be made with the utmost care. In all of my cases, except when life was immediately threatened, both internal and local measures were exhausted, either by myself or by the medi- cal gentlemen who referred the patients to me, before laparotomy was resorted to. CHAPTER XLIX. DISEASES OF THE UTERINE APPENDAGES (Continued). CONGESTION OF THE OVARY. Pain in one or in both ovarian regions is frequently met with, especially just before and during menstruation. This pain may be stinging or burning in character; or the patient will de- scribe it as a dull, cutting or sickening sensation. It is oftener met with on the left side, and radiates down the inner part of the thigh, or to the small of the back. It is usually worse some days previously to and during menstruation, and gives rise to that type of dysmenorrhea known as “ ovarian." Menorrhagia is likewise a frequent symptom, though in time the menses may become scant rather than excessive. The condition is often associated with neurasthenia and nervous manifestations of various kinds. There is tenderness upon pressure over the side affected. Other symp- toms are headache limited to the vertex, pain under the breasts of the corresponding side, constipation, flatulency and nausea and vomiting. In the worst cases there may be hysterical out- breaks and even hystero-epilepsy. The lesion of the ovary giving rise to this group of symptoms is described by many authors as chronic ovaritis, and, probably, the congestion many times results in inflammation. However, the symptoms characteristic of true inflammation are often wanting. There is, to be sure, more or less enlargement of the organ, but the subjective symptoms come and go, and, if the ovary is removed, the evidences of actual inflammation are wanting. Undoubtedly, pain of the character described is often due to simple congestion. When the ovary becomes surcharged with blood, its unyielding fibrous investing membrane prevents its expansion, and there is pain not unlike that resulting from orchi- tis. It is brought on and is made worse by any cause giving rise to pelvic congestion. Immoderate coitus, the various 763 764 A TEXT-BOOK OF GYNECOLOGY. methods resorted to for preventing conception, constipation, ungratified sexual desire, irritation of the uterus or of the cer- vix-any or all of these causes may result in simple conges- tion of the ovary, which stops short of actual inflammation. In the treatment of ovarian congestion it is necessary, first of all, to remove the cause or causes which tend to per- petuate the mischief. Rest is important. Long - continued standing or walking should be avoided; running the sewing- machine is responsible for many cases of ovarian congestion and inflammation. It is better for the patient while undergoing treatment to live absque marito, though nothing more fortunate could befall her than pregnancy, for utero-gestation followed by lactation, is the nearest approach to physiological rest which can be given the ovary. Unfortunately, most women thus affected are sterile. Constipation should be overcome and the hot douche administered once or twice a day. Two or three times a week a galvanic current of from fifteen to twenty milli- ampères should be passed through the parts, with the positive pole within the vagina. This should be followed by the intro- duction of a boro-glycerid tampon medicated with the fluid ex- tract of belladonna. Internally, belladonna, apis, cimicifuga, lilium tig., lachesis, collinsonia, and bryonia are the remedies oftener indicated. PROLAPSE OF THE OVARY. Non-adherent prolapse of the ovary is due, in nearly all in- stances, to chronic ovarian congestion or inflammation. One or both ovaries may be prolapsed, though the left, for obvious reasons, is the one oftener displaced. The symptoms of this accident are sufficiently urgent to call for special consideration. Symptoms.-Ovarian prolapse is often associated with retro- displacement of the uterus. There are few complications which it is more difficult to contend against without resorting to radical measures, than a retroflexed fundus under which is a prolapsed ovary. The condition gives rise to pain upon walking which is of a sickening, throbbing character, and is especially aggravated by stool. It is located in the inguinal or sacral region and extends down the thighs. The paroxysm is frequently precipitated by PROLAPSE OF THE OVARY. 765 some unusual effort, as jumping from a carriage. Dyspareunia of a most distressing character is likewise caused by the dis- placement. The mental and nervous symptoms do not differ from those described under the head of chronic congestion of the ovary. Diagnosis. The peculiar sickening character of the pain, aggravated as it is by walking, stool, and sexual intercourse, will suggest the cause of the difficulty. Upon making a digital examination a small almond-shaped tumor will be found in the posterior fornix which, when pressed upon, is exquisitely tender, and gives rise to a sinking sensation in the epigastric region, and sometimes to actual vomiting. If not adhered, it can be pushed out of the cul-de-sac. The excessive tenderness will serve to differentiate the displaced ovary from a small pedunculated fibroid. It can be distinguished from a retroflexed uterus by passing the sound. Treatment. The various measures having for their object the relief of pelvic congestion should be applied. If the uterus is retro-displaced, this should be reposited and a suitable pessary fitted. Unfortunately, the position of the ovary will not often permit the use of a Hodge pessary. Sometimes an air pessary (Fig. 119) will be tolerated when no other form can be worn. The knee-chest posture frequently resorted to is of much value, as are also the hot douche and properly applied tampons. A soft lambs-wool tampon placed in the posterior fornix while in the knee-chest posture, is often the only form of support which the patient can endure. (v. p. 150.) The general measures recommended for ovarian congestion may be tried. Unfortunately, after the organ has been pro- lapsed for some time, it is exceedingly difficult to effect a cure without permanently fixing the uterus in front. The condition gives rise to so much distress and suffering that, after all ordi- nary measures have been exhausted, the physician is justified in performing laparotomy, removing the offending organ, and, if the uterus is retro-displaced, attaching it to the anterior ab- dominal wall. 766 A TEXT-BOOK OF GYNECOLOGY. OVARIAN NEURALGIA (OVARALGIA). Ovarian neuralgia, or ovaralgia, may be due to a number of causes. Of these the so-called neuralgic diathesis is first to be mentioned. This means, in most instances, some depravity of the system, the result either of improper food, excessive tea- drinking, or undue exposure. Ludlam is of the opinion that daughters of rheumatic fathers inherit a special tendency to ovaralgia. Undue sexual excitement, disease of the uterus, and traumatism are other causes worthy of consideration. Symptoms. The patient is suddenly seized with an acute paroxysm of pain of a most intense character. It is oftener limited to one ovary, though it may implicate both. Like all ovarian pain, it frequently extends down the corresponding thigh. There is no chill, no fever, and no constitutional disturbance. The paroxysms come on without premonition, and ordinarily leave quite as suddenly. This is characteristic of neuralgias in general. Diagnosis. The absence of constitutional disturbance, the erratic character of the pain, the diathesis of the patient, and the absence of sequelæ will differentiate the condition from ovaritis. It may be mistaken for hysteralgia or neuralgia of the uterus. The latter affection is due, in at least ninety-five per cent. of all cases, to fluid finding its way into the uterine cavity through the cervix. The pain resulting from hysteralgia is more central, and is not of the peculiar sickening nature which character- izes all ovarian lesions. Treatment.-The curative treatment must be directed to the diathesis. If there is anemia or chlorosis these should receive attention. Nutritious food and proper exercise are important. Any sexual irregularities should be corrected. Nearly all neu- ralgic patients are exceedingly sensitive to sudden temperature changes, and, therefore, should go warmly clad. Ludlam re- commends that the lower part of the abdomen be protected by an extra layer of flannel. During the paroxysm the pain is to be relieved by the hot douche, or sitz-bath. Hot external applications are exceedingly gratifying. If the rectum is distended with fecal matter it should be emptied. During the interval between the paroxysms a gal- OVARIAN CONGESTION AND NEURALGIA. 767 vanic current of from fifteen to twenty milliampères, used twice or three times a week, will often put a stop to the attacks. It relieves the congestion of the ovary, which is so frequently present, and acts as a local sedative. Therapeutics of Ovarian Congestion and Neuralgia. Apis mel.-Stinging pains in ovaries; enlargement of the right ovary, with cough; aggravation after sexual intercourse. Bryonia. Soreness of right ovary, causing irritation and dragging pains, extending down the thighs; ovaritis with rheu- matic affections; shooting pains extending toward the hips; all symptoms aggravated by motion. Belladonna.-Enlargement of the right ovary, with pressure downward, as if everything would drop out of the vulva; pains come and go suddenly, and are circumscribed, stabbing or dart- ing in character; CEREBRAL DISTURBANCE AND SPASMS. Naja. Ovarian neuralgia, with violent palpitation of the heart; cramp-like pain in left ovary; thin, whitish leucorrhea; languor and fatigue; organs seem to be drawn together, especially the ovaries and heart. Colocynth.-Stitches in ovaries; diarrhea; colic; pressure in abdomen; intense boring pain in ovary, causing her to draw up double.* Cimicifuga. Ovarian irritation with irritable uterus; hysteri- cal symptoms; rheumatism; dysmenorrhea or amenorrhea. Bromide of ammonium.-Ovarian neuralgia; uterine hemor- rhage from ovarian irritation or inflammation; dull, constant pain and hard swelling in left ovary. Hamamelis. Ovaritis following traumatism; soreness of ovaries extending all over abdomen; ovarian affections, with swelling and tenderness, worse at time of menses. Lilium tig.-Stinging, darting, cutting pains in left ovary, with sensation of swelling and tenderness on firm pressure; sym- * "The character of the pain in the colic of Colocynth may be transferred else- where. I remember once of curing a lady of ovarian colic, from which she had suffered for three years, with colocynth. The pains were griping, and were relieved by bend- ing double. There were no organic changes. Two cases of ovarian tumor have been reported as cured by colocynth administered on this symptom."-Farrington. 768 A TEXT-BOOK OF GYNECOLOGY. pathetic cardiac disturbances; pain extends down corresponding thigh. Ustilago.-Pain in right ovary, with metrorrhagia; burning pain in the ovaries shooting down the limbs, especially the left; neuralgic pains. Iodium.-Chronic congestion, with induration and enlargement of ovary; pressing, dull, wedge-like pain from right ovary to uterus and through sexual organs; great sensitiveness of right ovarian region during or after menses; atrophy with sterility. Consult:-Gelsemium, cactus grand., cantharis, graphites, lache- sis, ferrum, platina, mercurius, and mag. phos. CHAPTER L. ECTOPIC PREGNANCY. Definition.-Dr. Robert Barnes originated the term, ectopic pregnancy, to signify the development of the impregnated ovum at some point without the uterine cavity. I adhere to this term because, as suggested by Tait, "it gives a convenient and very complete definition without expressing any theoretical explana- tion of the condition." Other terms which have been put forth to signify the accident are, extra-uterine pregnancy, and extra- uterine gestation. A careful review of modern medical literature will clearly indicate the importance of the subject. I know of no trustworthy statistics showing the relative frequency of ectopic pregnancy as compared with normal gestation.* Of course, data of the kind, were they accessible, would indicate a very small proportion of ectopic pregnancies as compared with normal intra-uterine ges- tation; nevertheless, the accident is not an infrequent one, as every specialist who has to do with abdominal surgery well knows. In reviewing the literature of ectopic pregnancy one is almost overwhelmed with its vastness. The last ten years, and espe- cially the last five, have been most prolific ones in the creation of a special literature treating of the accident. Indeed, it seems almost useless to undertake, in a short chapter, to 'present even a resumé of it; and by some it may even be urged that the subject does not belong to gynecology at all. I cannot share this view. It belongs most decidedly and emphatically to the abdominal surgeon whether his line of work is in the direction of gynecology or of obstetrics. I think that most obstetricians will admit that gynecology has done much more * Dr. Joseph Price (American Journal of Obstetrics, December, 1892) presents statistics bearing upon this point, but he himself admits that they are valueless. 49 769 770 A TEXT-BOOK OF GYNECOLOGY. toward the development of abdominal surgery than has obstet- rics. I therefore deem no apology necessary for including in this work a chapter devoted to ectopic pregnancy. Varieties. Much confusion has been created by the innumer- able subdivisions and varieties presented by various authors. Tait, with his usual clearness of conception and love for sim- plicity of classification, presents the following:- SCHEME OF ECTOPIC GESTATIONS (IN TUBO-OVARIAN TRACT). I.—Ovarian, possible but not yet proved. II.—Tubal, in free part of tube, is (a) contained in tube up to fourteenth week, at or before which time primary rupture occurs, and then the progress of the gestation is directed into either- (6) Abdominal or intra-peritoneal gestation, uniformly fatal (unless removed by abdominal section), primarily by hemorrhage, sec- ondarily by suppuration of the sac and peritonitis; or, (c) Broad ligament or extra-peritoneal gestation. This may— (a) Develop in the broad ligament to full time, and be removed at viable period as living child; (6) Die and be absorbed as an extra-peritoneal hematocele ; (c) Die and suppurating ovum may be discharged at or near um- bilicus, or through bladder, vagina or intestinal tract; (d) Remain quiescent as lithopedion; (e) Become abdominal or intra-peritoneal gestation by secondary rupture; III.-Tubo-uterine or interstitial is contained in part of tube embraced by uterine tissue, and, so far as is known, is uniformly fatal by primary intra-perito- neal rupture (as b) before fifth month. While the foregoing classification possesses the merits of sim- plicity, it is necessary to state that it is not in harmony with the teachings of most modern authorities. Tait admits the possi- bility of ovarian pregnancy, but claims that its existence has not yet been proved. On the other hand, the majority of writers accept the recorded testimony of Parry and others, as proving conclusively that ectopic pregnancy may be located within the ovary. Again, the scheme implies the inevitable rupture of the tube before the fourteenth week of gestation; that it is impossi- ble for pregnancy within the tube to progress to term without rupture in one of the directions indicated. In refutation of this statement many cases are recorded showing that it is entirely possible for gestation to continue to full term without such rup- ECTOPIC PREGNANCY. 771 ture. Pozzi states that at least twelve cases of tubal pregnancy at term are known. Finally, the teaching that all cases of abdominal pregnancy are secondary, i. e., result either from rupture of the Fallopian tube directly into the abdominal cavity, or rupture of the tube first into the folds of the broad ligament .and then into the abdominal cavity, is contended against by some of the best and most original investigators. Tait bases his assertion, first of all, upon his large experience as an opera- A. a FIG. 178. B. a DIAGRAMMATIC SECTION OF FALLOPIAN TUBE, REPRESENTING THE TWO DIREC- TIONS OF RUPTURE. A. Into the peritoneal cavity. B. Into cavity of the broad ligament. a. Clot at point of rupture. b. Wall of Fallopian tube. c. Cavity of the broad ligament, with folds separated by hemic effusion, a. (Tait.) tor, which, it will be admitted by all, is most valuable evidence. He maintains that the peritoneal cavity is inimical to the life of an ovule, whether impregnated or not; that the serous mem- brane will quickly digest and absorb an ovule or early ovum, which comes in contact with its surface. It is, then, according to Tait, both a physiological and a pathological impossibility for an abdominal pregnancy to have its origin in this way. Other observers, on the contrary, teach that it is not only en- 772 A TEXT-BOOK OF GYNECOLOGY. tirely possible, but altogether probable, that the spermatozoa and ovules may remain in the peritoneal cavity for a long time without losing their vitality. This much in the way of introduction and to guard the reader against accepting in toto the teachings of Tait. Although Tait speaks dogmatically, he has the right so to do. His experience as an abdominal surgeon is both unique and remarkable. He does not reason from the standpoint of a theorist, but rather from that of one who is thoroughly familiar with his premises. If, then, we accept the classification given, we have to do with but three primary varieties of ectopic pregnancy—ovarian, tubal, and tubo-uterine or interstitial. The secondary varieties are, abdominal, and intra-ligamentary. For all practical purposes this classification is sufficient. In dealing with suspected ectopic pregnancy, it is quite enough, during the early period of gestation, for the clinician to locate the fetus without the uterine cavity. Nicety of diagnosis, as regards its exact location, is insisted upon by the "arm-chair" theorist rather than by the practical surgeon. Etiology. The greatest confusion prevails regarding the causes of ectopic pregnancy. This is not strange, inasmuch as many points pertaining to the physiology of normal menstrua- tion and conception are as yet unsettled. Tait teaches that the uterus alone is the seat of normal menstruation and conception; that the ciliated lining of the Fallopian tubes prevents sperma- tozoa from entering them and facilitates the progress of the ovum into the uterus; and that the chief object of the plications and crypts of the uterine mucous membrane is to lodge and retain the ovum until it is impregnated, dies, or is discharged. Any- thing, therefore, which interferes with the function of the cilia of the tube may not only interfere with the passage of the ovule into the uterine cavity, but may permit spermatozoa to enter the tube and impregnate the retained ovule. Bland Sutton* holds this view to be mere speculation, though admitting that it contains some elements of truth. Sutton, how- ever, maintains that it does not explain all cases. He contends * London Lancet, February, 1891. ECTOPIC PREGNANCY. 773 also that the usually accepted doctrine that the tubes are no1- mally the meeting place of the ova and the spermatozoa in the human family is pure conjecture. He has devoted much thought and research to the subject. "In the first place," he says, "salpin- gitis so severe as to promote destruction of the tubal epithelium causes such profound changes in the tubes as to lead to stricture and complete occlusion of the abdominal ostia. It is exceed- ingly rare to meet in tubes denuded of their epithelium patent abdominal ostia." He further affirms that a careful microscopic examination of several specimens of very early tubal pregnancy failed to disclose any evidence of loss of epithelium, or of old salpingitis. While in the light of the present conflict of opinion, due mod- esty of opinion regarding the causes of the accident is most becoming, the probability of preëxisting tubal disease acting as a causative factor, in at least a goodly number of cases, must be admitted. Ectopic pregnancy occurs oftener in women who have never had children, or who, after having had one or more, have gone for a long time without again becoming pregnant. There is, in the language of a well-known writer, a seeming "inaptitude" for conception, and a careful inquiry into the history of these cases will often elicit preëxisting symptoms of more or less pelvic distress, which are at least suggestive of tubal disease. To make ectopic pregnancy possible, the spermatozoa must find their way beyond the uterine cavity into the Fallopian tube, for of course it is most improbable that an ovule after impreg- nation will pass from the uterine cavity again into the tube. This much is certain, and from a practical standpoint it matters but little whether the point of contact of the spermatozoa and the ovule is within the tube, the ovary, or the abdominal cavity. Any disease interfering with the passage of the ovule into the uterine cavity will, therefore, predispose to ectopic pregnancy. Of the various affections, preëxisting inflammation, especially salpingitis, is undoubtedly the one most frequently responsible for the accident. It is not difficult to comprehend an occlusion of the tube sufficiently great to prevent the passage of the ovule into the uterine cavity, thus causing it to lodge at some point 774 A TEXT-BOOK OF GYNECOLOGY. within the tube, yet which would admit of the passage of sper- matozoa upward. The mucous membrane of the tube is very like that of the uterus, and since the ovule cannot find its way into the uterine cavity, it accommodates itself to the unnatural site, the Fallopian tube making a vicarious effort to care for it. To conceive of other causes than inflammation as giving rise to the accident, requires no great stretch of the imagination. The effect of moral and mental emotions in arresting the down- ward progress of the ovule is at least worthy of consideration. When it is remembered that excessive joy, grief, or fright may arrest or bring on menstruation, may arrest labor pains or pre- cipitate labor, it is not difficult to comprehend that such emotions may arrest the ovule at any point within the genital tract, or, indeed, may so reverse the action of the cilia as to convey sperm- atozoa entirely through the Fallopian tube into the abdominal cavity. Nor must we ignore the part played by traumatism, by uterine displacements, by tumors of various kinds, and, indeed, by those blood changes which so often exert a potent influence for evil upon all of the pelvic organs. Ectopic pregnancy may complicate normal pregnancy. Two interesting instances of this kind have recently been recorded. Hertzfeld delivered a woman, aged thirty-three, of her third child. The unusual size of the abdomen after labor led to the detection of a second living fetus without the uterine cavity. Laparotomy was performed, and the child, which died before the operation was commenced, extracted. Hertzfeld considered this to be a case of true ovarian pregnancy, basing his belief upon the fact that the right tube presented no evidences of solution of continuity. The funis was attached to the uterine annexa, and the appendages of the opposite side were in every respect normal. Worrall † removed, at the Sidney Hospital (N. S. W.), a fetus weighing nearly five pounds from a woman whose uterus con- tained a living child. The operation precipitated a miscarriage, both children perishing, though the mother recovered. Pathology.-Pathological changes will vary according to the location of the fetus. The uterus in all cases takes on a * Le Bulletin Médical, Paris, April, 1891. † Medical Press and Circular, London, March, 1891. an in- ECTOPIC PREGNANCY. 775 creased vascularity, and its mucous membrane, in anticipation of normal pregnancy, forms an imperfect decidua. The nearer the ectopic pregnancy is located to the uterus the more marked will be the changes within this organ. Thus, in interstitial pregnancy the walls of the corresponding side become decidedly thickened, and the whole organ is markedly increased in size. In Fallo- pian pregnancy, on the other hand, and especially if the ovum is lodged near the fimbriated extremity of the tube, the increase in the size of the uterus is not so great. Admitting the possibility of ovarian pregnancy, it is probable that, were it to occur, the vascularity of the uterus would be even less than in Fallopian pregnancy proper. In all forms of ectopic pregnancy the size of the uterus never corresponds to the period of gestation, although it always undergoes certain hypertrophic changes. In the early months of gestation a corpus luteum is usually present. Strangely enough, it is sometimes located in the opposite ovary. In abdominal pregnancy the sac may be composed either of the ovular membranes alone, or in addition to these an adventitious membrane, the result of peritoneal irritation. The modus oper- andi of the formation of this adventitious membrane does not differ materially from that enclosing an intra-peritoneal hemato- cele due to any cause. In abdominal pregnancy, whether primary or secondary, the fetus is sometimes found without any encysting membrane of any sort. It is claimed by Tait that this form of pregnancy, i. e., ectopic pregnancy within the free peritoneal cavity, is of exceedingly rare occurrence; that a rupture into this cavity, whether primary from the tube or secondary from the folds of the broad ligament, is almost invariably fatal unless an operation is at once resorted to. As an exception to this rule he cites the now famous Jessop case, in which the fetus was not encapsulated, but was absolutely free in the peritoneal cavity. In Jessop's case, Tait believes that the ovum was primarily within the Fallopian tube; that a rupture occurred at the tenth week, the ovum escaping into the right broad ligament; and that a secondary rupture took place at the seventh or eighth month, the fetus then escaping into the peritoneal cavity, where it continued its life amongst the intestines. The placenta was found "plastered 776 A TEXT-BOOK OF GYNECOLOGY. over the pelvic contents." Instances where the fetus is found in the free peritoneal cavity with absolutely no investing mem- brane are not of common occurrence. I think, however, that the case of my own, recorded on page 794, can be placed side by side with Jessop's case. The placenta may be attached to any, or, indeed, to all of the pelvic and abdominal organs. In broad ligament cysts it is often attached to all of the pelvic contents; at other times it may be found in intimate contact with some portion of the ab- dominal walls, the intestines, or the omentum. In my own case of intra-peritoneal pregnancy, it was utterly impossible to define its attachments. The position of the uterus will depend upon the location of the ectopic cyst: When within the folds of the broad ligament it is pushed to the opposite side and up- wards; when in the cul-du-sac of Douglas it is carried forward and above the pubes; and in the rare instances in which the cyst is located in front of the uterus, the organ is pushed backward. After the death of the fetus the cyst and its contents take on marked changes. In the vast majority of cases the fetus under- goes decomposition and suppuration. Occasionally, however, the liquor amnii is absorbed and the cyst shrinks. The fetus may also undergo calcareous degeneration and become converted into a lithopedion; it may be transformed into a peculiar mat- ter termed adipocere; or it may become mummified and indu- rated from absorption of its fluids. In rare instances it remains for an almost indefinite period unchanged. When the cyst undergoes degeneration it usually becomes attached to some of the surrounding organs; if to the vagina or bladder or the intestinal canal, its contents may be discharged through them after disintegration, or they may escape externally through the abdominal wall. It is claimed by Tait that in tubo-interstitial pregnancy rup- ture invariably occurs into the peritoneal cavity. The case coming under my own observation, whose record I append to this chapter, is, I believe, one of interstitial pregnancy in which the rupture occurred into the uterine cavity. Similar cases are recorded by Parkes, Monteil, Hodge, Mundé and Thomas. Symptoms. In by far the larger number of instances the existence of ectopic gestation is not suspected until the symp- ECTOPIC PREGNANCY. 777 toms of rupture present themselves. Very pretty clinical pictures of the early symptoms are put forth in most of the text-books, FIG. 179. A UTERUS AND ITS APPENDAGES, SHOWING GREAT DILATATION OF THE RIGHT FALLOPIAN TUBE, WHICH CONTAINS A FETUS OF ABOUT THE THIRD MONTH. (Museum R. C. S. Photographed by the Author.)* which, if in harmony with the facts, would enable the physician to diagnose ectopic gestation with but little difficulty. Unfor- *"From a woman, aged 22, admitted into hospital with severe pains in the hypo- gastrium, of a month's duration. Had menstruated regularly. A hypogastric tumor was discovered; it appeared to contain fluid and to be surrounded by large pulsating vessels. Because of the peculiar discoloration of the inner aspect of the vulva, preg- nancy was suspected. The tumor was tapped per rectum with an aspirator, and a pint of bloody fluid was thus removed. A styptic solution was injected to control hem- orrhage and at once drawn off. The patient died suddenly four days later, having passed a decidua on the third day. Blood was found diffused over the peritoneum and issuing from an aperture in the upper part of the back of the tubal cyst."- Dr. C. H. F. Routh. 778 A TEXT-BOOK OF GYNECOLOGY. tunately, clinical manifestations often occur with an obstinate disregard for set rules. This is preeminently true with the accident under consideration. A careful review of the clinical history, after rupture, will usually disclose the preexistence of more or less pelvic distress associated, possibly, with amenorrhea or irregular hemorrhages from the uterus; yet how FIG. 180. 4692 A UTERUS WITH THE FALLOPIAN TUBES AND OVARIES. The right tube is laid open and contains a fetus about an inch in length, with the extremities just budding. There is a large corpus luteum in the right ovary which is not shown in the illustration. (Museum R. C. S. Photographed by the Author.) many women suffer from quite as much distress and quite as decided irregularity of the menstrual function because of causes other than ectopic gestation. It must, therefore, be understood that what is said regarding the symptomatology during the early months, and up to the period of rupture, is subject to innumer- able exceptions. The symptoms may, however, be looked for in something like the following order :- ECTOPIC PREGNANCY. 779 1. Very often a considerable period of sterility followed by general and reflex symptoms of pregnancy. 2. Associated with the general and reflex symptoms of preg- nancy are those of disordered menstruation-usually irregular uterine hemorrhages attended by severe pelvic pain. FIG. 181. A UTERUS WITH ITS APPENDAGES. The fimbriated extremity of the left Fallopian tube is dilated into a thick-walled cyst two inches in diameter, which contains a fetus three-quarters of an inch long, with its membranes and placenta. The right ovary is cystically degenerated. Covering the peritoneum which invests the back of the uterus is a thick layer of decolorized fibrin which is partially turned down. (Museum R. C. S. Photo- graphed by the Author.)* 3. Symptoms of pelvic inflammation, especially marked by tenderness in one or the other iliac region. The tender area is frequently the seat of irregular spasmodic pains. * "From a lady, aged 31, the mother of three children. Four months before her death she ceased to menstruate; two months later an attack of severe hypogastric pain and collapse occurred, and in eight days a perfect decidua was discharged. This was followed in a few days by a second attack of pain in the hypogastrium, and a swelling above and to the left of the vagina was detected. She died within ten minutes of a third attack. Three thin layers of coagula were found in Douglas's pouch: the deepest, displayed in this specimen, most probably represents the first attack of hemorrhage; the middle layer was decolorized, but soft, and may have been the result of the second attack; the third was soft and dark red, evidently quite recent." (See "Trans. Obstet. Soc.," Vol. xxi, p. 169.)-Alban Doran. 780 A TEXT-BOOK OF GYNECOLOGY. 4. The presence of a pulsating tumor in the region of one or the other broad ligament, which is dense, sensitive and continues to grow. 5. Lateral displacement of the uterus which is slightly en- larged but empty. 6. An attack of severe pain in the pelvis followed by shock, collapse, and all of the symptoms of hematocele. 7. Renewed uterine hemorrhage with the expulsion of the decidua, wholly or in part. A clinical history such as the foregoing would, if presented entire, make the diagnosis very certain. I know of no means, however, whereby the average woman, otherwise healthy, can be made to consult her physician previously to the period of rup- ture, much less to subject herself to a careful physical examina- tion. If she be wise enough to adopt such a course, and there should be found at one side of the uterus a gradually growing tumor, possessing the characteristics given and attended by the symptoms enumerated, the patient should at least be carefully watched. The condition most liable to be confounded with early ectopic gestation is a retroflexed pregnant uterus. Jaggard * reports a case of this kind in which the vaginal portion of the cervix was so much elongated, and the lower uterine segment so thin and compressible, as to occasion great doubt. To add to the confusion there was pain, hemorrhage, and the expulsion of a supposed decidua. The genu-pectoral posture cleared up the diagnosis. Had the fundus been adhered the confusion would have been still greater. If the life of the fetus is not destroyed by the rupture, or if it continues to grow in the region primarily located without rup- ture, the symptoms will become more marked as time progresses. After the heart sounds are heard there is, of course, no longer any doubt as to the existence of pregnancy; it then remains only to determine its variety. As gestation advances the usual signs of pregnancy become more distinct. Irregular uterine hemorrhage may continue, especially if the decidua has not been entirely thrown off, for an * Journal Am. Med. Ass., January, 1891. ECTOPIC PREGNANCY. 781 indefinite period. The fetal heart sounds are often intensified because of the thinness of the intervening tissue. For the same reason the fetal movements are felt with greater distinctness than in normal pregnancy. After rupture, the spasmodic pains usually disappear for the time being, to recur, if the ovum survives, at a later period. They become unusually severe as gestation ap- proaches term. Physical exploration will reveal the uterus enlarged, but the in- crease in size does not correspond to the period of gestation. The cervical changes, although marked, are not as decided as in normal pregnancy. The entire organ is usually displaced later- ally, upward, and forward. A tumor will be found in the poste- rior cul-de-sac, and it is often possible to outline distinctly the fetal parts through the posterior vaginal wall. Upon inspection the absence of symmetry of the abdomen is very noticeable-the enlargement being greater upon one side. The increase in the transverse diameter is especially prominent. Palpation will indicate the superficial location of the fetus, though a reliance upon this sign is sometimes misleading. There is in this connection one source of error, alluded to by Parry and Tait, which may make the diagnosis very uncertain. I refer to extreme thinness of the abdominal and uterine walls in otherwise normal pregnancies. Such a case recently passed under my observation. The patient, æt. 27, was unmarried and had a kyphotic pelvis. The tissue intervening between the examining hand and the fetal parts did not seem much thicker than parch- ment. The distorted pelvis caused an irregularity in the abdominal enlargement which added greatly to the confusion. I first saw the case at the beginning of the eighth month of gestation, and remained in doubt as to the actual location of the fetus for four weeks, though making repeated examinations. At the beginning of the ninth month the uterine tissues began to increase in thick- ness, and I succeeded in reaching the presenting part through the cervix, which, of course, determined beyond all doubt the presence of the child within the uterus. In order to emphasize the importance of this point I cannot do better than quote in detail from Lawson Tait.* He says: * "Diseases of Women and Abdominal Surgery." 782 A TEXT-BOOK OF GYNECOLOGY. "This condition of extreme thinness of the uterine wall, in a preg- nancy perfectly normal in every other respect, is a point which has not yet received the notice it deserves. It is, however, of sufficiently common occurrence to be a source of difficulty and danger, and, therefore, I propose to say here what I have noticed about it, in the hope that it may draw the attention of some one engaged in obstetric practice who may be able to investigate it more fully. I can now recall eight cases in which I have been consulted concerning a sup- posed extra-uterine pregnancy, yet in which there was only an extreme thinness of the uterine walls. I have no record of three of the cases, but of the others I have more accurate data than mere recollection. The features of all of them have much in common, and the known histories of four quite establish this. The ordinary symptoms of preg nancy were present in all of them, and in only one was there any doubt as to its existence. The question generally was: Is the child in the abdominal cavity? and sometimes I had great difficulty in per- suading the gentlemen who brought the patients to me that the posi- tion of the child was normal. Save in one case that seen by me with Dr. Whitwell, at Shrewsbury—there was a marked absence of the liquor amnii, so that the movements of the child could be seen and felt in a most striking manner. In the pelvis the finger came upon the presenting part of the fetus, as if it lay immediately under the mucous membrane; and it was only on very careful investigation that the attenuated cervix uteri could be made out, spread over the body of the child.” At the end of the normal period of gestation in ectopic preg- nancy a spurious labor usually sets in. The pains are so much like those of natural labor that nothing wrong may be suspected until a physical examination reveals the unnatural state of affairs. They are intermittent and periodical in charac- ter. This spurious labor varies in duration from a few hours to two or three weeks. Occasionally it does not occur, but in most instances a careful inquiry into the history will reveal the fact that pains not unlike those of labor were present at or about the time fetal movements ceased to be felt. The pains vary greatly in severity, and it is their occasional trivial and fugitive character that causes the patient to forget ever having had them unless her memory is especially jogged. In most instances, however, they are sufficiently severe to cause most excruciating suffering. ECTOPIC PREGNANCY. 783 A hemorrhage from the uterus usually accompanies the spurious labor. It is followed by a discharge much like that of the lochia. It is probable that the fetus lives but for a short time after the occurrence of the false labor, and its death is to be ac- counted for by the changes which occur in the utero-placental circulation. Nature, even when working under great disadvan- tages, makes an effort to observe certain fixed laws. The time has come for fetal expulsion and cessation of the utero-placental circulation. The fetus, of course, cannot be expelled spontane- ously, but the placental circulation can be cut off, and is, though gradually. How long after the full period of development the child can live is a mooted question; it is not improbable that its life may be maintained for some time after the end of normal gestation is reached. After the death of the fetus it may undergo any of the changes which have been indicated under the head of pathology, though rarely does the system tolerate its existence for any length of time. An effort is usually made, sooner or later, to expel it through inflammation and suppuration. It is true that an en- cysted fetus is not incompatible with life, and indeed, with a fair degree of health and comfort. The condition is, however, one never devoid of danger, for with the slightest provocation the cyst is liable to become inflamed and to undergo suppuration. In those rare instances where the fetus has been carried for years it is transformed into a lithopedion or undergoes calcareous degeneration. Diagnosis.-Ectopic gestation is to be differentiated from— Acute pelvic cellulitis and peritonitis; Pelvic hematocele due to other causes than ectopic pregnancy; Conception in a rudimentary horn of a double uterus; Pelvic abscess; Uterine fibroids. In acute pelvic cellulitis and peritonitis no history of pregnancy will be elicited. There will be a history of inflammation, with the sudden formation of a tumor within the pelvis. The pecu- liar, spasmodic, colicky pains so characteristic of ectopic preg- nancy are wanting; there are no mammary changes and the uterus is but slightly enlarged. 784 A TEXT-BOOK OF GYNECOLOGY. In pelvic hematocele due to causes other than ectopic preg- nancy, it will many times be utterly impossible to make an abso- lute diagnosis. The absence of all preexisting signs of preg- nancy will at least lead the examiner to suspect that the source of the effused blood is some other than a ruptured extra-uterine pregnancy cyst, but, as I have already endeavored to show, these signs and symptoms are so often wanting in ectopic gesta- tion as to make their absence of little value in determining the actual cause of the hematocele. When conception occurs in one side of a double uterus cer- tainty of diagnosis is oftentimes utterly impossible. The changes in the uterus are very much greater than is the case in ectopic pregnancy proper, and our chief reliance will have to be placed upon these changes. In pelvic abscess, due to causes other than suppuration of an ectopic pregnancy cyst, there will be a clinical history of the primary lesion-inflammation, pyosalpinx, etc. In uterine fibroids there is no history of pregnancy. The tumors are painless. Their presence does not ordinarily give rise to spasmodic, colicky pains, and they do not grow with the same rapidity as does a cyst due to ectopic pregnancy. Should fibroids complicate intra-uterine pregnancy the confusion may be very great (v. p. 611). It is not often possible to determine the variety of ec- topic gestation. There are certain peculiarities, however, per- taining to each variety which are worthy of consideration. In abdominal pregnancy, for instance, the uterus will be found en- tirely empty. Its size will not be increased as markedly as in the other two forms, and the child can be moved about in the abdominal cavity very much more readily than is the case when enveloped either by the tube or the folds of the broad ligament. In tubal pregnancy the enlargement will be more unilateral and the tumor somewhat separated from the uterus. Ballotte- ment is much more distinct than in the abdominal variety. In- terstitial pregnancy is the rarest of all forms. It gives rise to an irregular enlargement of the uterus and is intimately connected with it, though the organ will be found empty. The diagnosis, after the death of the child, may present many ECTOPIC PREGNANCY. 785 difficulties unless, indeed, suppuration has already occurred and pieces of the fetus have been expelled through the bowel, vagina, abdominal wall, or bladder. The history of the case will ordinarily afford much valuable information. Patients believe themselves to have been pregnant, and, if they also re- late a history of spurious labor followed by cessation of the fetal movements, the diagnosis is pretty certain. After the death of the fetus the abdomen decreases in size and the cause of the enlargement may be attributed to some other condition—ova- rian cyst, fibroid tumor, cancer, etc. While the examiner should rely much more upon physical signs than upon the history given by the patient the most careful physical exploration may fail to reveal the actual condition. If the symptoms of sup- puration present themselves, the pus should be evacuated as soon as expedient and the remains of the fetus removed. This will, of course, clear up the diagnosis, and in most instances promote a cure as well. Prognosis.-Ectopic pregnancy is always a serious condi- tion. It is said that the abdominal variety is the most favorable of all, but even here the prognosis is quite bad enough. If rupture does not occur before the fourth month, there is strong probability that gestation will continue until term, at which time there is again the greatest liability to rupture. In the event of rupture, if it occurs in the free peritoneal cavity, the larger proportion of cases die as a result of the hemorrhage unless operative interference is immediately resorted to. Rupture into the folds of the broad ligament, as we have seen in deal- ing with extra-peritoneal hematocele, is a much less fatal acci- dent. After the death of the fetus, suppuration and blood-poison- ing usually terminate life. It is true that a patient may carry an extra-uterine fetus for an indefinite length of time without serious inconvenience or distress, but this is a rare exception to the general rule, and she is never free from danger while so doing; a slight accident of any kind may excite suppuration. It is true also that spontaneous recoveries are reported after suppuration sets in, the fetus being expelled piecemeal through some of the avenues already mentioned. That a few recoveries 50 786 A TEXT-BOOK OF GYNECOLOGY. under these circumstances should have taken place only proves. the physical endurance of some women; it certainly does not justify an expectant plan of treatment after the diagnosis has been made. Treatment. With the frightful mortality attending unmo- lested ectopic gestation confronting us, there is little need of argu- ment in favor of some form of operative treatment. Death from hemorrhage, peritonitis, septicemia or exhaustion, is the termina- tion in such a very large proportion of cases as to have caused a general acceptance of the proposition laid down by Werth* to the effect that "Extra-uterine pregnancy is a malignant neo- plasm and should be treated as such." A woman's life is in jeopardy as long as she carries an ectopic cyst, and the danger begins from almost the very inception of pregnancy. Even after the fetus has been transformed by degenerative changes into an "inert mass," the danger is very great. The treatment, therefore, is simply reduced to a question of method and time for operative interference. The conflict of opinion that exists among modern authorities has to do largely with the management of the gestation when the patient's life is not immediately threatened by rupture or hemorrhage. In the treatment of ruptured cyst with active hemorrhage the dictum of Stephen Rogers, enunciated as long ago as 1867, to the effect that "The peritoneal cavity must be opened; the bleeding vessels must be ligated," † has become the guiding principle of all surgeons. * "Extra-uterine Gestation and the Early Signs which Characterize it.” † I desire again to call attention to the fact that the credit of this dictum belongs to the late Stephen Rogers, an American surgeon. The quotation given is taken from the "6 Transactions of the American Medical Association" for 1867, the essay (which fairly teems with suggestions which have now become recognized surgical principles) being reprinted in pamphlet form. In reviewing Lawson Tait's "Lec- tures on Diseases of the Ovaries," in 1888, I called his attention to Rogers's essay. A copy of the review falling into Mr. Tait's hands led him to write me, thanking me for calling his attention to the essay of Rogers, of which he had never previously heard. I sent him my only copy, but he does not allude to it in his "Diseases of Women and Abdominal Surgery," which was given to the profession early in 1889, except in a quotation taken from Parry. Parry gives Dr. Herbert (also an American surgeon) the credit for first suggesting gastrotomy to save a woman dying from early rupture of the cyst. Whether Mr. Tait has elsewhere acknowledged the bold teaching of Rogers (and it was indeed bold at that early date) I do not know. Parvin, ECTOPIC PREGNANCY. 787 Previously to the period of rupture the questions, then, which confront the surgeon are: Shall the abdomen be opened and the cyst removed as soon as discovered? Shall measures be resorted to, having for their object the destruction of the ovum ? Or shall the pregnancy be permitted to continue to term with the hope of delivering a living child through the abdomen? 1. Shall the abdomen be opened and the cyst removed as soon as discovered? As has already been intimated, ectopic pregnancy is not suspected in by far the larger number of cases until rupture occurs. If a fairly certain diagnosis can be made of an ovum within the Fallopian tube, or if the patient present symptoms which in themselves give rise to suffering sufficiently great to justify an exploratory operation, I think that the indications are clearly to open the abdomen, and, if an ectopic pregnancy cyst be found, to remove it at once. The possibility of the abnor- mal gestation continuing to term without interruption is so remote, and the maternal dangers are so great, as to make this course almost imperative. But let the uncertainties of diagnosis at this period be borne in mind. The surgeon who is governed in all cases by dogmatic rules will probably more than once open the abdomen to find that the tumor is not due to an ectopic pregnancy, but to some other pathological condition. Since an exploratory incision in the hands of a skilled laparotomist under modern antiseptic methods is not a very dangerous procedure, the mistaken diagnosis will ordinarily be followed by no bad results; and if the local symptoms are such as to simulate ectopic pregnancy, the disease, usually a pyosalpinx, can be removed. After the fifth month, if the fetus is dead, I think that an abdominal section should undoubtedly be made. There may be some question as to the advisability of laparotomy imme- diately after death occurs, i. e., before the cessation of the utero- placental circulation. The majority of the authors advise against the immediate operation because of the increased danger from hemorrhage. In its favor there is to be said that there is and Thomas (the last edition of Thomas & Mundé) also mention the teachings of Rogers only in an incidental way. This rather surprises me, for, in the light of 1867, Rogers's radical arguments show him to have been a man of clear conception and great originality. 788 A TEXT-BOOK OF GYNECOLOGY. much less danger from peritonitis and septicemia, and since we have learned to control hemorrhage by gauze packing, the danger from bleeding is reduced to a minimum. As soon as sepsis manifests itself, an operation is not only indicated but imperative. I think, too, that even in those instances where the fetus has been transformed into a lithopedion, and tolerance of it is prac- tically established, the danger of non-interference is much greater than is an operation for its removal. A “quiescent lithopedion," as is shown by Tait, Campbell, Parry, and others, is of decidedly rare occurrence, and a woman is never for a moment safe while carrying within her abdomen the products of an ectopic gesta- tion. Other considerations calling for immediate operative interfer- ence are suppurating fetal cysts, and pregnancy in a rudimen- tary uterine cornu. In the first instance, even though the cyst abscess is already discharging, the processes of nature must be hastened. In the majority of cases it is not necessary to open into the abdomen, the fistula indicating the preferable point for incision. When the fetus is within a rudimentary cornu the mortality in unmolested cases, according to the statistics of Bandl, is over seventy-seven per cent. Owing to the difficulty of obtaining a suitable pedicle, it is best to remove the entire uterus, as in Porro's operation. 2. Shall measures be resorted to, having for their object the de- struction of the ovum before laparotomy is performed? It is a well-known fact that if the ovum perish during the early weeks of gestation it ordinarily gives rise to no further trouble. We have seen that it is altogether probable that when Fallopian preg- nancy ruptures into the broad ligament, ovular death with absorption is the rule rather than the exception. This, at least, is the teaching of Tait and others of extended observation. We have seen, too, that it is utterly impossible, in by far the larger number of cases, to distinguish a broad liga- ment hematocele due to ruptured ectopic pregnancy from one due to other causes. Since this is the case it seems to me emi- nently proper, when the rupture has evidently taken place into the broad ligament, to resort to measures which tend to destroy ECTOPIC PREGNANCY. 789 the life of an early ovum. From present data it is difficult to estimate the value of electricity for this purpose. The accuracy of diagnosis is ever to be questioned, even in the hands of men whose reputation is established; yet I think that the utility of electricity can hardly be denied in properly selected cases. I would not use it if I thought that the ovum were still within the Fallopian tube, for fear of inducing rupture; nor should I use it in large ectopic cysts. I should limit its use to broad ligament hematoceles, whether due to ectopic pregnancy or to other causes, with a view, first, of destroying the vitality of the ovum, and, secondly, of promoting the absorption of the hematocele. We have in galvanism an invaluable agent for the latter purpose, and it is reasonably certain that a strong galvanic current passed through the tumor will also kill an early ovum. Since this is so I cannot conceive of galvanism doing any great amount of harm, and it may do much good. It is at least worthy of trial. On the other hand, I cannot conceive of anything more unsur- gical than the destruction of the fetus by galvanism, or by any of the methods presently to be mentioned, after the fourth month. After this period the changes following the death of the fetus are such as to make its destruction, to my mind at least, a most unwise procedure. Electro-puncture and faradization have also been used with alleged success. Electro-puncture strikes me as a more dangerous expedient than is exploratory laparotomy, and infi- nitely less satisfactory. The faradic current, restricted to the class of cases which I have described, would probably be harm- less, though the recent experiments of A. Martin go to prove the greater destructive properties of the galvanic current. Martin passed a strong faradic current, and a galvanic current of fifty milliampères, through a large number of eggs in different periods of incubation. Eighty per cent. of those acted upon by faradism hatched, while none treated by galvanism did so. The injection of morphin, strychnia, ergotin, etc., and the internal administration of iodid of potassium, mercury, and other similar agents for the purpose of killing the ovum, have been resorted to in the past, and are still mentioned by a few 790 A TEXT-BOOK OF GYNECOLOGY. writers as justifiable procedures. Attention is called to them under this head only for the purpose of condemning their use. They are all inferior to electricity and infinitely more dan- gerous. 3. Shall the case be permitted to continue to term with the hope of delivering a living child through the abdomen? In considering this question we are again confronted with the most diverse opin- ions of men whose authority is established beyond peradventure. It seems to me that the rights of the fetus have been in the past too much ignored. After the fifth month there is certainly a fair prospect of gestation continuing to term without rupture, and, should rupture occur, the danger attending gastrotomy is not so very much greater than is the operation previously to the acci- dent-providing, of course, the patient is easily accessible. This is especially true if we can convince ourselves that in all probabil- ity the pregnancy is abdominal. Jessop, Eastman, Braun, Breisky, Tait,* and Koeberle† have all succeeded in delivering living children through the abdomen. In my case of intra-peritoneal pregnancy I believe that the child could have been saved had the operation been performed earlier. At any rate the results already obtained force the claims of the fetus upon us after the fifth month. During the early period of ectopic gestation the maternal dan- gers are so great, and the chances of the ovum surviving the period of rupture so slight, that we are compelled to ignore these claims. After the fifth month, however, we can only look upon any operation having for its object the inevitable death of the fetus. as a stigma upon the obstetric art. The brilliant results obtained by Tait and others, justify the hope that during the coming ten years feticide, even in ectopic gestation, will be practised much less often than formerly. Nevertheless, here, as in all branches of abdominal surgery, fixed rules and dogmatic teaching will ever be set aside by the surgeon whose skill and ingenuity make him equal to any exigency or emergency. Such a one will look upon the delivery of a living child at term through the abdominal wall, from a living mother, as "the crowning triumph of obstetric sur- gery." He will not, however, when the odds are greatly * Tait has saved three children and two mothers. + Koeberle saved four mothers and seven children out of nine operations. ECTOPIC PREGNANCY. 791 against the mother, hesitate to sacrifice the fetal life for the sake of saving hers. The general principles to be observed in the management of ectopic pregnancy may be summed up as follows:- I. When life is threatened by hemorrhage from a ruptured cyst, no matter what the period of gestation may be, the abdo- men should be immediately opened, the bleeding point secured, and the products of the conception removed. Immediate laparotomy should also be resorted to if a fairly certain diagnosis can be made previously to the fifth month; if symptoms of septicemia present themselves at any period of gestation; if suppuration occurs; and, finally, if the products of an ectopic pregnancy are found in the form of a lithopedion, even though apparent tolerance has been established. 2. We are not justified in resorting to measures for destroying the life of the fetus except when rupture occurs into the broad ligament previously to the fourth month, when galvanism may be used. 3. After the fifth month if the fetus is living we are justified, if the conditions are favorable, in temporizing, with the hope of delivering at term a living child through the abdomen. This with a full consciousness that many cases will present elements of danger demanding immediate operative interference. Technique of the Application of Electricity.-One pole is applied as closely to the tumor as possible, either through the vagina or the rectum. If the galvanic current is used, the negative pole should be the direct one. A large dispersing elec- trode is placed over the abdomen. The strength of the current should range from twenty-five to seventy-five milliampères. The sittings should continue for from ten to fifteen minutes, and should be repeated every other day until the tumor ceases to grow and diminishes in size. A sharp faradic current may be passed for a short time after the galvanic. Technique of Laparotomy for Ectopic Gestation.-The general principles of abdominal section, applicable in all cases of laparotomy, are, of course, to be observed. These have been elsewhere discussed (Chapter XLVI), and I shall at this time refer to a few special points only. 792 A TEXT-BOOK OF GYNECOLOGY. Before and soon after the death of the fetus the great element of danger is hemorrhage. In early tubal pregnancy there is no difficulty in obtaining a pedicle, and the entire mass should be ligatured and cut off. The abdominal wound may then be closed either with or without drainage, as the case may require. From the fifth month on, such a course as this is rarely ever practicable, for it is usually extremely difficult to remove the entire mass. If the sac can be more easily reached by making a lateral abdominal incision this should be done. Indeed, the lateral incision is ordinarily preferable to the central, for there is less danger of opening into the peritoneal cavity. If it is possible to reach the sac without invading the peritoneal cavity, Tait recommends the following procedure:* "When the sac is opened the fetus is to be carefully lifted out by the feet, using great care not to lacerate the sac or abdominal wall. If the child is living some one disengaged should take immediate charge of it. The umbilical cord should be cut off quite close to the placenta, the placenta squeezed as empty of blood as possible, the sac cleansed of all blood, loose membranes, etc., and then washed with warm water, the sutures carefully placed, the sac again washed out with clean water by means of a siphon trocar, and the stitches drawn tight, with a small trocar still in the wound. The sac should then be emptied of all the water possible, the trocar taken out with precautions against admission of air, and the wound totally closed." Tait thinks that this is the best method of dealing with the placenta, and he has tried all. He has twice removed it entire, in each case saving both the mother and child. The hemor- rhage was controlled by perchlorid of iron. Occasionally it is possible to secure the main vessels of the pedicle, when the placenta should always be removed. Oftener the attachments. are extensive, and the placenta should be left unmolested. When the peritoneal cavity is opened into, care should be taken not to injure the placenta in opening the sac. If it is clear that the removal of the sac will be attended with great difficulty it should be stitched to the abdominal wound. No * " Extra-uterine Pregnancy," Strahan, 1889, p. III. ECTOPIC PREGNANCY. 793 traction should be made upon the placenta and cord. The sac may now be treated as recommended by Tait, or it may be washed out with a 1 : 4000 bichlorid solution and packed with iodoform gauze. The gauze can be safely left in the cavity for three or four days. If the vagina can be easily penetrated without injuring the placenta, a T drainage-tube may be passed into it through the bottom of the sac. After the removal of the gauze the cavity is kept thoroughly clean by frequent irri- gation. The placenta is detached piecemeal and the cavity gradually closes by granulation. A glass tube may be intro- duced instead of the gauze. The method of hermetically sealing the placenta within the cyst cavity, as recommended by Tait, is unquestionably the preferable one when it can be accomplished. By it the placenta is absorbed without decomposition and suppuration is done away with. Should decomposition supervene the sac can be re- opened and the decomposed placenta removed with but little danger from hemorrhage. If the fetus has been dead for some time, matters are much simplified. It is now no longer advisable to close the wound hermetically. If placental decomposition is already established the organ can be removed at once and hemorrhage controlled by gauze packing. An effort should be made to remove the entire sac. Drainage is here a sine qua non. In those rare instances where the fetus is intra-peritoneal and without any investing membrane, as in Jessop's case and my own, there is no sac other than the entire abdominal cavity to deal with. In Jessop's case the child was living and the placenta covered the inlet of the pelvis like the lid of a pot, and extended some distance posteriorly above the brim where it ap- parently had an attachment to the large bowel and posterior abdominal wall." (Strahan.) Jessop did the only possible thing to do under the circumstances, and left it entirely untouched. In my case, the placental attachment was quite as extensive, involving the uterus and annexa as well as the omentum. had to do with a large putrid mass within the free abdominal cavity of a patient whose system was already surcharged with septic poison. To have left it behind would have been simply I 794 A TEXT-BOOK OF GYNECOLOGY. criminal. I therefore took away all removable sources of hem- orrhage and septic infection. In so doing, although observing a broad surgical principle, I had to create a precedent, for I had not, up to the time of operating, been able to find a recorded instance of ectopic pregnancy other than interstitial, in which the entire uterus and annexa were removed with the fetus and placenta. Elytrotomy or Vaginal Extraction.-Elytrotomy in ectopic pregnancy still has its advocates. I have had no experience with it nor do I think that I ever shall have. The restricted field of operation, the difficulty of controlling hemorrhage, and the remarkable results obtained by the abdominal method will deter me, I think, from undertaking the vaginal. I can, however, imagine that with one inexperienced in abdominal surgery the temptation to extract a fetus easily felt projecting into the vagina, by elytrotomy, would be very great. Pinard's method, as given by Pozzi,* is as follows:- "Anesthesia; exploration of the vaginal cul-de-sac and puncture with the knife at a point where the absence of arterial pulsation has been ascertained. Introduction of the finger into the buttonhole for exploration, then enlargement by multiple inci- sions, and dilatation by the use of the fingers. The hand pressed into the sac grasps the feet and brings them to the vulva by slow and continued traction. Then the trunk and the breech are engaged. The two arms are successively disengaged and then the head extracted. The cord is cut and search is made for the placenta. If it can be easily removed, it is gently detached with the fingers; if it adheres, no matter how little, it is better to leave it. The cavity of the cyst is then washed out freely with a sublimate solution 1: 5000, or a saturated aqueous solution of naphthol-ß. I am inclined to think that the introduction of iodoform gauze would be preferable to the frequent injections advised by Pinard; the gauze may be removed every three or four days, and might be left even longer in place. If symptoms of putrid infection appear by reason of insufficient antisepsis, continuous irrigation might be used.” Illustrative Cases. CASE LXXXVII.—Non-encysted Intra-peritoneal Pregnancy. Operation. Re- covery. (North American Journal of Homeopathy for October, 1889.) Mrs. E. C., actress, aged 23 years, dark hair and eyes, petite and very intelligent. Patient of Dr. Sara J. Allen of Charlotte, Michigan. Married, June, 1888, just thirteen months previously to the operation, at which time she was menstruating regularly, but the flow never appeared after marriage. The following November, fearing pregnancy, * "A Text-Book of Gynecology,” p. 506. ECTOPIC PREGNANCY. 795 she for the first time consulted a physician, who made an ineffectual effort to produce an abortion. After a rest of four or five days she returned to the stage. While engaged in her work as an actress, she sustained three bad falls, suffering as a result much and continuous pain. In February of this year (1889) she had a severe attack of peritonitis, preceded by collapse and syncope. She was confident of feeling motion and life previously to and during this attack, notwithstanding the assurance of several physicians who at the time examined her, that no pregnancy existed. Going from town to town, numerous medical men were appealed to, and not in vain, to undertake an abortion. The repeated criminal efforts were unavailing, and she, too, became dissuaded, believing her condition to be due to other causes than pregnancy. On the morning of July 23, Dr. Allen sent for me. I found the patient in a pre- carious condition, with a pulse 145, and a temperature 104°. Sepsis was marked, as was shown by the pulse, temperature, color of the skin and profuse perspiration. The abdomen was the size of a full-term pregnancy and very sensitive; the enlarge- ment was uniform and symmetrical. The vagina was equally sensitive, and the patient could not tolerate an examination which was in the least sastisfactory. I could, however, feel a large fetal head low down between the vagina and the rectum, the sutures being felt with distinctness and the plasticity of the head easily observed. The intervening tissues did not seem to be thicker than heavy parchment. This examination made me mistrust an extra-uterine pregnancy, a condition which Dr. Allen strongly suspected before my arrival, and I requested that another assistant be secured, so that, if our suspicions were confirmed by an examination under ether, an operation might be proceeded with. We accordingly got everything in readiness to meet any emergency. At 1.30 P. M. the patient was placed on the table under the influence of ether. The head was found in the position described, evidently occupying the Douglas pouch. The cervix was high up above the pubes, and could be dragged down but a short distance by the volsella. The finger could be passed through the canal only to the internal os. A probe penetrated the uterine cavity three inches. The fetal parts could be easily detected through the thin abdominal walls, and I imagined that I could hear the placental bruit, though I fully appreciate the deceptive nature of this sound, especially under the circumstances with which I had to contend. Feeling confident that the child was not within the uterine cavity, and with the concurrence and assistance of the attending physician and Dr. J. W. Siegfried, then of Charlotte, I prepared to open the abdomen. Operation.-Observing antiseptic precautions as thoroughly as possible, an incision was made midway between the pubes and the umbilicus, in the median line. I did not make a lateral incision because the perfect symmetry of the abdomen gave no clue as to the side upon which the sac was located-if it were upon either side. The first stroke of the knife brought me to a membrane resembling the peritoneum as found over adherent ovarian tumors. Catching this between two forceps and nicking it, a stream of fluid, either amniotic or ascitic, gushed out. The abdominal walls were quite vascular, and several catch forceps had to be applied to spurting arteries. It now became necessary to enlarge the abdominal incision so that it extended at least two inches above the umbilicus. The feet of the child were then grasped by the left hand and an effort made to deliver it through the wound. This could not be done until the head was peeled out, as it were, from the cul-de-sac of Douglas, after which a five-pound putrid fetus, thickly covered with vernix caseosa and with the skin 796 A TEXT-BOOK OF GYNECOLOGY. broken in many places owing to the high state of putrefaction, was delivered through the abdomen. The hemorrhage at this stage became frightful, the patient exsan- FIG. 182. a b e THE AUTHOR'S CASE OF INTRA-PERITONEAL PREGNANCY. FETUS AND PLA- CENTA WITH UTERUS AND ANNEXA.-(Wood.) a. Peritoneum stripped from base of the broad ligament. b. Base of the broad liga- ment. c. Outer border of left broad ligament d. Fundus of uterus at the point of section e. One of the inflammatory bands extending to transverse colon. (The omentum is not shown.) guinated, and it was evident that something had to be done, and that quickly. Instructing Dr. Siegfried to throw some brandy under the skin, I quickly threw ECTOPIC PREGNANCY. 797 an elastic ligature around the entire mass and packed sponges about the pedicle. This controlled the hemorrhage very effectually and gave me an opportunity to wash the clots from the abdominal cavity by pouring hot water into it from a pitcher. The next point to contend with was the management of the placenta. It was very evident that the peritoneal cavity could not be excluded from the cyst cavity, for the only cyst cavity that I could detect was the peritoneum, unless, indeed, the cul-de-sac occupied by the head could be called such. I found no traces of a gestation sac other than the attachment of the omentum to the mass which I had included in the elastic ligature, and several bands of inflam- matory tissue springing from the pelvis and attaching themselves to the transverse colon. A more careful examination showed that my ligature had embraced the left broad ligament, between whose folds the placenta was attached, the entire fundus of the uterus and both tubes. The inclusion of the uterus could only be determined by failure to find it in any other locality, for it was utterly impossible to distinguish or separate the various structures of the mass; indeed, in my opinion, it would have been the most reckless folly to have undertaken it. To detach the placenta was entirely out of the question; to leave it within the abdominal cavity, the peritoneum being more or less destroyed at the lower border of the broad ligament and the system already saturated with septic material, seemed equally unsafe. I therefore transfixed the pedicle above the ligature with a couple of Wilcox pins and cut away the entire mass —placenta, uterus and appendages—permitting the stump to rest at the lower angle of the wound, as in supra-vaginal hysterectomy. The omentum seemed unhealthy, very much thickened and even gangrenous, and this too was tied and cut away. The bands of inflammatory tissue were secured in the same way. In short both the abdominal and the pelvic cavity were completely emptied of any tissue or substance that could slough or decompose. The abdomen was again thoroughly washed with hot water and sponged dry, but owing to the continued oozing of blood from the Douglas cul-de-sac a glass drainage tube was passed into the bottom of the cavity. The patient's condition would not permit of longer delay in contending with the hemorrhage so the pelvis was packed with iodoform gauze, one end of which was left projecting from the abdominal wound. The abdomen was then closed and the stump dressed in the usual manner, when the patient was placed in bed, very weak, but soon rallying under the influence of warmth and hypodermic stimulation. The pulse dropped in nine hours after the operation to 116, and the temperature to 101°, without any evidences of profound shock. The temperature fluctuated between 101° and 102°, one day reaching 104° for a short time, approaching the normal about the sixteenth day. Nourishment was freely taken and retained from the first. The gauze was removed at the end of the second day, blood-stained but sweet. Smaller drainage tubes were substituted from time to time, but drainage was entirely discarded on the twenty-sixth day. The cavity was kept thoroughly clean by suction and fre- quent washing. The pedicle and ligature were removed on the sixteenth day, the entire cervix coming away through the vagina on the seventeenth day. This seemed to me most unusual, and, to make sure that it was the cervix and not a decidua, I had the mass sent to me for examination. I also had Dr. Allen make a vaginal examina- tion before completing my record, and she reported an entire absence of the cervix. It is probable that the elastic ligature fell below the utero-vaginal mucous membrane, thus severing the cervix and permitting it to fall into the vagina, the fundal end of the stump adhering to the lower end of the abdominal wound for several days longer. Ала 798 A TEXT-BOOK OF GYNECOLOGY. The patient was able to take a drive just one month from the day of the operation and ultimately recovered perfectly. CASE LXXXVIII.—Interstitial Pregnancy Rupturing into Uterus. Recovery.— Mrs. S., aged forty years; brunette; somewhat below the medium stature, and of rather a nervous temperament, but of the finest type of womanly character. Commenced menstru- ating at fifteen. Her only child is ten years old, and twelve months after the birth of this child she had a miscarriage at the second month. The miscarriage was not fol- lowed by any serious sequelæ, menstruation recurring at regular intervals, being normal in quantity and duration the following seven years. Three years before I saw her she had an attack of pelvic peritonitis, caused by undue exposure of some sort, which came very near proving fatal; an inflammatory deposit was left behind which caused consider- able pain and inconvenience. From that time on she sufferred from menorrhagia, which at times was alarming. One year before I saw her this became so bad that she was compelled to take to her bed and place herself under the daily attendance of Dr. James M. Long of Coldwater, whose patient she was. The examination then made revealed, besides the inflammatory deposit, a fibroid involving the posterior wall and fundus of the uterus. She was very much emaciated and very anemic from the loss of blood, but by the properly selected remedies in conjunction with daily local treat- ment, she so far recovered, as to be able to spend a season at the Northern Lakes, which added to the improvement already begun at home. The menorrhagia, how- ever, remained more or less severe. About the middle of the following January she was again taken with unusual symptoms, which for the second time necessitated almost daily attendance. She suffered from dull, heavy bearing-down pains in the pelvis extending to the back and down the thighs; great lassitude, with an obstinate hacking cough; anemia from the long continued drain upon the system; leucorrhea, with at times clots of matter and blood in the discharges. There was no nausea or vomiting. On the 29th of March, 1885, Dr. Long requested me to examine the case with him. Besides the facts given above I elicited the following: The usual menstrual flow made its appearance in January. In February she was unwell but one day, and in March, just four weeks from the day she was unwell in February, menstruation again appeared, and so far as quantity and duration were concerned this was the most natural period she had had for three years. She had ceased flowing three days be- fore I was called as counsel. I found her very much in the condition described above. The uterus could be plainly outlined through the lax abdominal walls, ex- tending as high up as the umbilicus, the fundus tipping backward and to the left. There was, in the region of the left Fallopian tube, a distinct tumor about as large as a small fetal head, with a broad base continuous with the left uterine wall. It seemed hard and gave a perfectly resonant sound on percussion. Upon making an examination per vaginam the cervix was found hypertrophied, elongated, and directed forward; the os was dilated so as almost to admit the index finger, and from it there oozed a thick, sanious discharge. As far as the finger could discern through the posterior cul-de-sac the uterus was indurated and irregular. The uterine cavity measured five inches. I could discover nothing in the interior of the womb by exploration, though the whole cavity was explored as thoroughly as possible with the sound. The history of the case, as well as the physical signs, seemed to point un- mistakably either to a sub-peritoneal or interstitial fibroid. For the purpose of curing the hemorrhage the curette was thoroughly applied ECTOPIC PREGNANCY. 799 and brought away the usual débris found in fungoid endometritis. An application of impure carbolic acid followed the use of the curette. On the morning of April 28, she began to have peculiar bearing-down pains, but no more severe than had often preceded the advent of the menstrual period. The pain increased in severity until the first of May-thirty days after the use of the sound and fifteen days after the curetting-when a somewhat distorted but well preserved fetus of three months was expelled. The flooding was alarming, but by the timely arrival of Dr. Long this was controlled, and the patient, under the influence of stimulants, soon rallied from her syncope. The following four or five days she was very low from a condition simulating shock, with much tenderness and pain in the region of the left Fallopian tube; there was retention of urine and evidences of circumscribed peritonitis. Under the influence of china, veratrum, and bryonia, with antiseptic vaginal injections she rapidly improved, and, I believe regained her health perfectly. A subsequent examination revealed no evidences of a double uterus and I cannot but feel that this was a case of interstitial pregnancy which ruptured into the uterine cavity. The following case I present as one fairly illustrating the out- come of ruptured extra-uterine pregnancy cysts if not inter- fered with. The older literature abounds with numerous illus- trations of the kind, CASE LXXXIX.—“ Extra-uterine Pregnancy. Rupture. Death.—Mrs. M., mar- ried, aged twenty-nine years, has had two living children; no miscarriages. She called at my office February 6, 1884, complaining of dull pain in the right iliac region, back, and rectum. There seemed to be a tendency to hysteria. She had had only a slight flow at her last menstrual period, and was afraid she might be pregnant. Great difficulty attended a vaginal examination, the mucus membrane being hyperesthetic. The uterus was in its normal position. On its right side a round, soft body could be felt, apparently of about the size of a walnut. Conjoined manipulation was rendered impossible by the rigidity of the abdominal muscles. The patient had not had connection with her husband since the completion of her last menstrual period. I did not think she was pregnant, and considered her case one of chronic oöphoritis. I was called again on the night of the 24th of February. After having been up most of the day, the patient was taken with very severe neuralgic-like pains referred to the region of the heart, and suffered from globus hystericus. It was learned from her attendant that the symptoms developed while she was having some dispute with her husband. "The following week I attended her husband for alcoholism, and at that time Mrs. M. was not complaining much, but worried a good deal about her husband, and had had one or two hysterical attacks, with pain in the abdomen and rectum. On March 7th, she had another attack similar to the first, and from that time the attacks became more frequent, some pain over the abdomen and in the rectum existing in the intervals. The patient was confined to her bed most of the time. On one or two occasions there was some nausea and vomiting, which I attributed to morphin. I had now gained the confidence of the patient, and learned that she was troubled a great 'deal, mentally, on account of domestic difficulties, and that the acute attacks were always preceded by mental strain and excitement. At no time was there an 800 A TEXT-BOOK OF GYNECOLOGY. increase of temperature. It was almost impossible to make a satisfactory examina- tion of the genital organs, which was attempted on several occasions. On the 16th she had another severe attack, one of her children having had a fall in her presence. She described the location of the pain as being " in front and back passages;" also over the abdomen and heart. There was nausea, with pallor and coldness of the extremities. A vaginal examination could not be made, but I thought I could feel a tumor, by external palpation, situated directly over the symphysis pubis. The patient soon felt quite well again, and I left the house with my mind fully made up to call Dr. George T. Harris in consultation the next day, give ether, and make a thorough examination; but, finding the patient feeling well the next morning, and being busy, I neglected to do as I intended. The patient passed a good night, and was feeling well. Shortly afterward she called for the chamber, had some trouble in passing her water, immediately followed by cries of distress and ‘Go for the doctor; I am dying.' When I arrived I found her in a condition of collapse, with hardly perceptible radial pulse, pale and exsanguinated. I at once suspected internal hemorrhage, ordered external heat, gave hypodermic injections of brandy, ether, etc., and sent for Dr. Harris, who confirmed my fears of hemorrhage, and, from the history, suspected extra-uterine gestation with rupture of the sac. The patient gradually sank, and died at 3 P. M."—American Journal of Obstetrics, Vol. xviii, p. 406. CHAPTER LI. INJURIES RESULTING FROM CHILDBIRTH. LACERATIONS OF THE CERVIX UTERI. History and General Considerations.-Lacerations of the cervix are produced in nearly all instances by parturition. Sir James Y. Simpson first called attention to the frequency of the accident, and, later, Dr. Gardner, in his work on "Sterility," described somewhat in detail cervical lacerations and their results. Dr. Gardner's work was published in 1856. Five years later Professor Roser of Marburg drew attention to ectropium of the cervix, especially dwelling upon the condition as a cause of cervical ulceration. (Thomas.) He, however, like Simpson and Gardner, did not appreciate the full importance of the subject and its frequent association with lacerations. The true significance of cervical lacerations was first recognized by Dr. T. A. Emmet, who published his first paper upon the sub- ject in 1869. This paper was unquestionably one of the most important contributions ever made to the literature of gyne- cology. Nevertheless, it was not until the publication of his second paper, five years later, that its full importance was appreciated. Since 1874 trachelorrhaphy, by which name the operation for the closure of cervical rents is known, has steadily grown in favor, though, like most innovations in medi- cine, it has met with bitter opposition. Not a few men have undertaken to build up a special uterine pathology based upon cervical lacerations. As a result many cervices have been operated upon which were better unmolested. Dr. Emmet called attention to the various symptoms liable to arise from the deposition of cicatricial tissue within the cervix, and from the resulting ectropium, not the least important of which being certain reflex neuroses. He, however, never claimed that trachelorrhaphy is a "cure-all." Indeed, he has been 51 801 802 A TEXT-BOOK OF GYNECOLOGY. most earnest in his efforts to impress upon the profession the fact that operative cases must be selected with care and discrimination. Notwithstanding his protests a certain class of men do not look beyond the cervix for the origin of reflex phenomena. If a cervical rent, no matter how slight, is found, further inves- tigation ceases. Trachelorrhaphy is advised and performed, but the promised relief does not follow, because the operation was not indicated. It is not strange that indiscriminate work of this kind should have induced the more conservative specialists to call a halt. Fortunately, the operation has now reached its proper level, and the indications for it are pretty clearly defined. As a result it is performed by men of experience much less often than formerly. When it is indicated, however, there are few gynecological procedures more beneficent, and the profession owes to Dr. Emmet unstinted gratitude for his labors in this direction. There Frequency. The accident is of frequent occurrence. are few women who have given birth to children at term whose cervices are not more or less torn. As a general rule the rents heal spontaneously, though some trace of them is usually left behind. It is evident, therefore, that if all women having cervical lacerations were operated upon, nearly every woman who has given birth to a child would have to subject herself to the sur- geon's knife. Clearly defined lacerations are met with only in about thirty-three per cent. of parous women. Etiology.—Under this head it will be necessary to consider only those causes connected with parturition. One of the most prominent of these is early rupture of the membranes, fol- lowed by uterine pains sufficiently strong to force the head through the undilated canal; the cervix not being sufficiently dilated, and more or less hard and unyielding, a tear is almost inevitable. An abortion as early as the third or fourth month may give rise to such an accident, for, in early abortion, the cervical tissues have not undergone marked changes and the unyielding cervix is very liable to give way. Cervical hyperplasia and endometritis, by their degenerative influence, predispose to lacerations, especially if associated with cystic disease. LACERATIONS OF THE CERVIX UTERI. 803 Unquestionably the unskilful use of obstetric instruments is responsible for cervical injuries in many instances. Yet, as in perineal lacerations, the accident is oftener due to the tardy ap- plication of the obstetric forceps than to its skilful and timely use. However, cervical tears of the most serious character will occur in the hands of the best obstetricians; it is, therefore, un- just to censure the attending physician, as is often done, when the injury is discovered by another. It occurs oftener at the birth of the first child than at subsequent labors. Varieties. These are:- 1. Lateral; uni- and bi-lateral (Figs. 70, 72, and 183); FIG. 183. FIG. 184. BILATERAL LACERATION; UNEQUAL DIVISION MULTIPLE INCOMPLETE LACER- OF THE CERVIX. (Skene.) ATION. (Skene.) 2. Multiple or stellate (Figs. 68 and 184); 3. Antero-posterior, the posterior lip being the most frequent site; 4. Incomplete. Here the solution of continuity is limited to the mucous membrane and muscular wall of the cervix, and does not extend to the mucous membrane of the vagina. Lateral lacerations are oftener located on the left side of the cervix, probably because of the greater frequency of the left occipito-presentation. 804 A TEXT-BOOK OF GYNECOLOGY. Pathology. Cervical lacerations are so intimately connected with subinvolution, endometritis (cervical and corporeal), areo- lar hyperplasia, cellulitis, inflammation of the uterine append- ages, etc., as to make it impossible to discuss their pathology without frequently referring to these complicating lesions. After the production of a laceration the wound may heal spontaneously without in any way interfering with the involu- tion of the uterus. If, however, the healing process is interfered with because of septic or other influences, nature may make an effort to close the rent by the deposition of cicatricial tissue. This interferes with the uterine circulation, keeps the organ con- stantly congested, arrests involution, and, in due time, gives rise to fungoid endometritis. The tubes, ovaries, and broad ligaments likewise participate in this congestion. The uterus, as a result of the increased weight, frequently becomes displaced. There is be- sides more or less squeezing of the terminal nerves by the cicatri- cial plug, and as a consequence pain in the pelvis, thighs, and in- deed in any part of the body may be produced. Emmet insists that general anemia of a most profound character may result indirectly from the cicatricial deposit. If the rent is not filled in by this unnatural tissue the os re- mains gaping and the whole cervical mucous membrane is more or less exposed. It is consequently subjected to constant fric- tion against the vagina, which gives rise to congestion, hyper- plasia, and cystic or papillary degeneration. The epithelium is destroyed by the resulting friction, and the underlying surface is left raw and exposed, which constitutes an erosion. When the hyperemia and hyperplasia involve the fundus of the uterus, fungoid endometritis, with menorrhagia or metrorrhagia, re- sults. If the rent is a lateral one, and has extended to the base of the corresponding broad ligament, cellulitis of that ligament is of frequent occurrence. This is due primarily to the absorp- tion of septic matter through the rent, but it is perpetuated in a subacute or chronic form by the resulting cicatricial tissue, which interferes with the uterine and pelvic circulation. It is necessary in studying the pathology of the accident to refer to the possibility of malignant degeneration following in its train. Emmet, Breisky, and others have especially empha- LACERATIONS OF THE CERVIX UTERI. 805 sized the importance of cervical lacerations and injuries as caus- ative factors in the production of epithelioma. It seems to me not unreasonable to believe that cystic and papillary degenera- tion, which so frequently result, the presence of lowly organ- ized cicatricial tissue, and the constant friction due to the ectropium, must necessarily favor malignant degeneration. At any rate, epithelioma occurs much oftener in women who have borne children than in nulliparæ. Symptoms. These are most variable in intensity and char- acter. The average woman will go through life with a cervical laceration without suffering the least inconvenience from it. Even when the pathological changes referred to have taken place the symptoms are not necessarily distressing. The type of temperament asserts itself here as in all gynecological affec- tions. In one patient a slight laceration, with comparatively insignificant complicating lesions, will produce the most intense distress. In another an extensive laceration with erosion, ever- sion, subinvolution, and hyperplasia, will create little if any general disturbance. Usually, however, the endometritis, metri- tis, subinvolution, and other complicating factors, give rise to more or less local and general distress. Menstrual irregularities, particularly menorrhagia and dysmenorrhea, are common symp- toms. There is likewise more or less leucorrhea due to the en- dometritis. The most common seat of pain is the sacro-lumbar region. Ovarian tenderness is frequently a marked symptom also. In short, any of the phenomena studied under the head of the various lesions enumerated as complicating factors may occur. As time goes on malnutrition due to disturbance of the gastro- intestinal tract, with consequent anemia, often becomes marked. The reflex symptoms are most variable. Many of these have been studied in the chapters devoted to the hystero-neuroses, to which the reader is referred. Pain in the head and lower limbs, infra-costal and infra-mammary neuralgia, profuse salivation, hysterical joints, supra-orbital neuralgia-these and reflex phe- nomena without number may, and often do, result from cervical lacerations. Upon digital examination the changed condition of the cervix. 806 A TEXT-BOOK OF GYNECOLOGY. will be noted. If there is eversion the external os will be gaping, and often the finger can be passed almost to the internal os. If hyperplasia exists the tissues will feel hard and resisting. There is increased sensitiveness at the angles of the rent where the de- posit of cicatricial tissue is greatest. The cervix loses its normal shape, the degree of distortion depending upon the extent and character of the laceration. In cases of erosion there will be seen through the speculum a raw, vascular surface, which is sometimes partially concealed by the two lips of the cervix. Occasionally the external os is but little larger than normal, yet if the sound is passed 'through it into the cervical canal the latter may be found greatly distorted. This is the so- called "circular laceration" described by Emmet. It is easily overlooked by the inexperienced examiner, because of the ab- sence of eversion. The erosion may be entirely wanting, even in the worst cases. I have many times found it absent in cer- vices markedly enlarged by the deposition of cicatricial tissue and hyperplasia. If the cervix is not indurated by hyperplasia, and the amount of cicatricial tissue in the angles of the rent is not great, the eroded surface may be entirely rolled in by tem- porarily coaptating the lips with two tenacula. Differential Diagnosis.—It is sometimes difficult to differen- tiate simple erosion in nulliparæ from laceration. Care must, therefore, be observed to guard the reputation of virgins where such a condition exists (v. p. 435). It is impossible in nulli- paræ to reinvert the lips of the cervix as can ordinarily be done when laceration is responsible for the eversion. In cases where papillary and cystic degeneration are marked the condition may be mistaken for epithelioma (v. p. 436). Here the microscope. must be the final test. Should there be much hyperplasia the disease may be confounded with scirrhous cancer (v. p. 451). Prognosis.-Eliminating the possibility of malignant degen- eration, the prognosis, as regards life, is always favorable. Cer- vical lacerations alone never kill, and, as we have seen, may give rise to no inconvenience whatever. It is the complicating lesions which must be considered in determining the prognosis. The presence of the laceration is often first made known by some undue exposure, unusual strain upon the nervous system, or the LACERATIONS OF THE CERVIX UTERI. 807 onset of pelvic inflammation. In chronic pelvic inflammation and uterine congestion the presence of the cicatricial plug per- petuates the difficulty, and in order to cure these affections this must be removed. So, too, in cervical and corporeal endome- tritis, especially if eversion and erosion are marked. Much relief, and even a temporary cure of the more distressing symp- toms, may be brought about by proper palliative treatment. But until the parts are restored to their normal condition by a suitable operation the patient will usually relapse into her former state of ill health after the treatment is discontinued. Clearly, then, the significance of cervical lacerations depends rather upon the symp- toms produced than upon the extent of the tears. This fact must be borne in mind in considering the prognosis. Immediate improvement, except in the neuroses, is not the rule. This fact must be impressed upon the patient. The operation will place her in a condition so that gradual improve- ment will continue until she is perfectly restored to health. This may require from three months to a year, depending upon the existing lesions as well as upon the general symptoms which such lesions have induced. Treatment.—The palliative treatment should be directed to any of the various complicating lesions, which have been enu- merated, that may exist. Cervical catarrh and hyperplasia, sub- involution, cystic and papillary degeneration, periuterine inflam- mation, etc., can all be greatly benefited by the various measures which are recommended for these conditions when they present themselves as pathological entities. In all, the intelligent use of the hot douche is invaluable. It should be used for its thermic properties; hence, in very large quantities and very hot. The application of the compound tincture of iodin to the cervix and vaginal fornices, alternating with applications of impure carbolic acid to the cervix alone, will do much good when the hyper- plasia is marked. In cases of cystic and papillary degeneration local scarification will hasten the cure. The vaginal tampon, made of cotton-wool and properly medicated, will not only support the parts, but by the pressure produced will promote the absorption of any existing inflammatory exudates. In the event of con- traction of the utero-sacral ligaments this should be overcome 808 A TEXT-BOOK OF GYNECOLOGY. by intelligently applied pelvic massage. If there is relaxation of the vagina, with cystocele or rectocele, the saturated solution of alum may be advantageously used in connection with the boro-glycerid tampon. This treatment, repeated twice or three times a week, and persisted in from one to three months, will ordinarily afford the greatest relief; indeed, in the slighter forms of laceration this may be all that is necessary. In the worst cases, however, the only way to bring about a permanent cure is to resort to trachelorrhaphy. If the perineum and pelvic floor are injured, these should be repaired at the same sitting. Indications for Trachelorrhaphy.-When called for, there is no operation more satisfactory than is trachelorrhaphy. The cases which, in my hands, have been most benefited by it are of two classes: subinvolution, with menorrhagia due to fungoid endometritis; and hyperplasia of the cervix with a large amount of cicatricial tissue. If reflex and nervous symptoms are par- ticularly marked this is an additional indication for the opera- tion even though the laceration is not extensive. Should dysmen- orrhea and menorrhagia attend the laceration it is necessary, ordinarily, to combine with trachelorrhaphy divulsion and cu- retting. Not more than ten per cent. of all cervical lacerations require an operation. Operation. The patient is prepared, as for any operation within the vagina, by having the bladder and bowels previously emptied. A copious, hot, antiseptic douche is administered just before she is placed upon the operating table; this must be hot in order to obtain its hemostatic effects, at least two gallons of water being injected. General anesthesia is advisable. The posi- tion of the patient will depend upon the predilection of the oper- ator. Formerly I used almost altogether the Sims posture. More recently I have been using the Fritsch speculum, and with the patient in the lithotomy posture the parts can be kept con- stantly irrigated without wetting her. In order to expedite the operation there should be four assistants-one to give the anes- thetic, one on either side of the patient to support the knees, hold the speculum, and make themselves generally useful during the operation, and a fourth to look after the sponges. There should be conveniently at hand two trays containing the follow- LACERATIONS OF THE CERVIX UTERI. 809 ing instruments: Two tenacula; one Mundé's counter-pressure hook; one Wood's wire twister (Fig. 95); one Sims's shield; one pair of Emmet's cervical scissors; one pair of Skene's ten- aculum forceps; one blunt-pointed uterine scalpel; one pair of wire scissors; six trocar-pointed cervix needles, straight and curved; four Wood's sponge holders (Fig. 94), containing sponges of suitable shape; one uterine sound; perforated shot; one needle holder; two coils of pure silver wire, Nos. 27 and 28; braided silk and catgut. The upper speculum is attached to an irrigating apparatus containing a I: 5000 bichlorid solution. After the water is turned on, the vagina is thoroughly washed with the fingers and with a sponge held in a holder. The anterior lip of the cervix is first seized between the points of Skene's volsella and trans- fixed with a needle armed with a long braided silk. This is next passed through the posterior lip, then drawn from the cer- vical canal with a tenaculum, severed, and the two separate loops tied. These "guy sutures" will give the operator perfect control of the cervix. Their introduction requires but a moment's time and the trouble is more than compensated for by the advantage gained. An applicator dipped in impure carbolic acid is now passed into the uterine cavity. If the nervous symptoms are at all marked, or if there is a history of obstructive dysmen- orrhea, the cervix is forcibly divulsed. If there is subinvolution and menorrhagia, the sharp curette is next applied to the entire endometrium, the débris wiped away, and a second application of the impure carbolic acid made to the entire endometrium. This practice I consider very important and undoubtedly the good results obtained from trachelorrhaphy are enhanced by it. With the patient upon her back the mucous membrane covering the upper border of the posterior lip is caught in a tenaculum, from which point it is removed to the corresponding left angle. That of the anterior lip is dealt with in the same way, care being taken to make the dissection extensive enough to remove all of the cicatricial tissue, particularly at the angle of the rent. The denudation of the right rent, in cases of bilateral tears, is done in exactly the same way. Ordinarily, a strip of mucous membrane a quarter of an inch wide, is left between the two 810 A TEXT-BOOK OF GYNECOLOGY. vivified surfaces, as shown in Fig. 185. This is for the creation of the new cervical canal. It is, however, of the greatest import- ance that all of the cicatricial tissue and diseased glands should be removed, even if the cervical canal must be invaded in order to accomplish this. If I fear occlusion of the canal, I insert a Cleveland glass plug (Fig. 60), but rarely is there danger of such an accident if the sutures are properly inserted. I do not hesitate to sever the circular artery if necessary to do so in order to reach all of the cicatricial tissue. I once unwittingly penetrated the folds of the broad ligament on each side, so that the two fingers could be readily passed to the fundus uteri.* Under a stream of bichlorid the requisite number of sutures was inserted, and before the wound was closed the uterus was packed with iodoform gauze for the purpose of controlling the free oozing of blood. FIG. 185. AREA OF DENUDATION IN TRACHELORRHAPHY. (Thomas and Munde.) The gauze was removed on the second day and the patient made an uninterrupted recovery. However, so extensive a dissection as this is unnecessary and not advised, but the danger attend- ing injury to the circular artery has, I believe, been greatly exaggerated. For the removal of the cicatricial tissue I use almost altogether the scissors shown in Fig. 186. By picking up with a tenaculum the hard deposits, which can be felt distinctly with the finger, they are easily removed with the scissors. Some operators prefer for this purpose the uterine scalpels shown in Figs. 84 and 187. *North American Journal of Homeopathy, June, 1891. LACERATIONS OF THE CERVIX UTERI. 811 After the diseased tissue has been removed and the denuda- tion completed, the parts are temporarily brought together by the aid of the guy sutures to determine whether or not approx- imation will be complete when the cervical sutures are introduced. If the hemorrhage is profuse and comes from the circular artery it can be controlled by passing deeply in the angle of the wound a wire suture, and temporarily twisting it; or, the spurting arteries can be secured by fine catgut ligatures. In FIG. 186. GETLE MANN EMMET'S CERVICAL SCISSORS. 00 Sims's posture the upper row of sutures is first passed; in the lithotomy posture it is a matter of indifference whether the right or the left side of the wound is first closed. Care must be taken to insert the sutures farthest from the operator, as high up as possible in order to insure complete closure of the angles of the wound. A cervical needle armed with a silk leader, in the loop of which is placed a silver wire ten or twelve inches in length, is seized with the needle holder and carried from without FIG. 187. G.TIEMANN & CO. SCOTT'S UTERINE SCALPEL. inward (Fig. 188). The number of sutures will vary from two to six on each side, depending upon the extent of the tear. It is not wise to place them too close together-ordinarily about four to the inch. After a suture is passed, the ends are quickly twisted together and given to an assistant, or placed under the blade of the speculum. When all are passed, the operator approximates the two sides of the wound, securing first the sutures at the upper angles; this is done under a stream of 812 A TEXT-BOOK OF GYNECOLOGY. bichlorid. Instead of twisting the sutures I now use perforated shot for the purpose of securing them, because, if the twisted wire is used, no matter how cautiously the ends are bent upon themselves, it is liable to become buried and lost.* More than once I have left twisted sutures behind. That this experience is not peculiar to myself is proved by the writings of Mundé, Emmet and others. After the sutures have all been secured the vagina is again irrigated, wiped dry with sponges, and a strip of iodoform gauze packed about the cervix with one end left projecting from the ostium vaginæ. The gauze is introduced to support the parts should the patient vomit from the effects of the ether, and is removed as soon as the retching ceases. FIG. 188. T INTRODUCTION OF SUTURES IN TRACHELORRHAPHY. The after-treatment is very simple. The patient is placed in bed, where she is kept for two weeks. The sutures are removed on the tenth day, unless menstruation should make its appearance at or about that time, or unless the perineum was restored at the same sitting. She is permitted to urinate spontaneously from the first, if able to do so. After urinating, a small sublimate douche should be given. When the catheter is used the cleans- ing douches are not called for. * I have, during the last three months, been experimenting with the continuous chromicized catgut suture for this purpose and, so far, have every reason to feel satis- fied with the results obtained. This does away with the necessity of removing the sutures, a consideration worthy of attention when the after-treatment is left in the hands of one unaccustomed to removing them. LACERATIONS OF THE CERVIX UTERI. 813 Lumbar pain from dragging upon the cervix is the most con- stant symptom, and is usually made better by a few doses of cimicifuga. If there is much tenderness or soreness over the abdomen an ice-bag may be applied. Mundé recommends that if there is retro-displacement a Hodge pessary be introduced before the patient is removed from the operating table. In order to remove the sutures the patient should be placed before a good light and the parts exposed with a Sims speculum. The first suture is caught in catch-forceps and severed with wire scissors. This is repeated until all are removed. The higher sutures can be located with the finger if they are not brought into view by the speculum. The patient is permitted to get up and about at the end of the second week, although if there is marked subinvolution and pelvic congestion it is well to keep her quiet longer than this. In the meantime the various meas- ures having for their object the relief of existing complications should be brought into requisition. It cannot be said that trachelorrhaphy is entirely free from danger, but the danger, if counter-indications do not exist, is practically nil. The operation should not be done if acute in- flammatory symptoms are present, or if the uterus is bound down by adhesions. The danger from sepsis, if antiseptic pre- cautions are resorted to, is very slight. A few deaths have re- sulted from this and from pelvic inflammation; usually, how- ever, serious pelvic inflammation is due either to uncleanliness or to the fact that the counter-indications have not been care- fully observed. If the operation is properly performed the parts rarely, if ever, fail to unite. When imperfect union takes place it can be attri- buted, in most instances, either to excessive suture tension, to sepsis, or to the depressed state of the general health. Should hypertrophic elongation of the cervix complicate the laceration the redundant tissue must be amputated. In doing this care must be observed not to injure the bladder, rectum, or pouch of Douglas (Figs. 117 and 191). The hypertrophy may be limited to the vaginal portion, or it may implicate the supra- vaginal portion and body of the uterus. When met with in virgins, it is probably due to inflammation. The diagnosis 814 A TEXT-BOOK OF GYNECOLOGY. I is easily made by digital and conjoined examination. prefer Simon's method of amputation. This is done by ex- cising a wedge-shaped mass from the two lips, after which the vaginal and cervical mucous membranes of either lip are stitched together. Hegar removes the tissues by a circular am- putation, and then brings together the vaginal and cervical mucous membranes by a circular row of interrupted sutures. In conclusion, it is necessary to allude to the probability of the recurrence of the laceration should the patient again become pregnant. The statistics of Wells show that a relaceration occurs only in about twenty per cent. of all cases in which the condition was noted after labor (Thomas and Mundé). It is not probable that, unless conception occurs very soon after the operation, the patient is any more liable to sustain a subse- quent laceration than are nulliparæ. CHAPTER LII. INJURIES RESULTING FROM CHILDBIRTH. (Continued.) LACERATIONS AND INJURIES OF THE PERINEUM AND PElvic FLOOR. General Considerations and Anatomy.-There is no sub- ject connected with gynecology more important than the one under consideration. The frequency of these injuries, the dis- tressing symptoms resulting from them, and the numerous methods which have been devised, especially during the last ten years, for their correction, make them, I think, of unusual interest.* The almost countless operative procedures, having for their object the restoration of the perineum and pelvic floor, are the outcome of numerous and widely differing theories put forth by specialists and anatomists regarding the function of the structures involved. The student is earnestly advised to study carefully, before considering in detail the symptoms and treat- ment of these injuries, the chapter devoted to the anatomy of the pelvic organs. It is absolutely essential for him to com- prehend the functions of the several structures of the pelvic floor if he expects successfully to contend with the accidents and injuries following in the train of parturition. The pelvic floor, considered as a whole, is made up of mus- cular and connective tissues which are so interlaced as to form a firm and resisting diaphragm. These extend from the pubic rami and ischia to the coccyx and sacro-sciatic ligaments, thus closing the pelvic outlet (v. Figs. 4, 5, and 7). The pelvic floor is pierced in the female by the vagina and the rectum. The anus and lower extremity of the rectum are separated from the lower extremity of the vagina by a triangular body known as the * In the treatment of this subject I have borrowed liberally from the admirable chapter by Dr. Howard A. Kelly in the "American System of Gynecology," Vol. II. 815 816 A TEXT-BOOK OF GYNECOLOGY. perineum (Fig. 2). The importance of the perineal body as a sup- porting structure is variously estimated. Thus, Kelly maintains that its efficiency is inversely proportionate to its depth-very deep perineums being weak and shallow, short ones strong. If the perineum is considered as a separate part of the pelvic floor, this view is unquestionably correct. If, on the other hand, we look upon it as intimately connected with the pelvic floor by the combination of muscle, fascia, vessels, nerves, fat, and areolar tissue, its importance as a supporting structure will be neither under-estimated nor unduly exaggerated. Being intimately blended with these structures, it helps to sustain the posterior vaginal wall and the anterior rectal wall, thus preventing their prolapse, at the same time furnishing a support upon which the anterior vaginal wall and bladder rest. Again, it directs the contents of the rectum during defecation backward, thus pre- venting the rectum from being forced into the vagina in the form of a rectocele, as it also prevents a cystocele by the support given to the bladder. The levatores ani, which, together with their fascial coverings, are by all odds the most important structures of the pelvic floor, extend transversely across the pelvis at the upper portion of the median line of the perineum. These muscles, together with the transversus perinei and infra-vaginal portion of the triangular ligament, can be felt by carefully palpating the posterior vaginal wall just behind the hymen. They appear to the examiner as a band or sling of fibers, which is sufficiently under the control of the patient so that by it the vaginal orifice can be contracted or relaxed. The fibers of the levatores ani hug in their embrace both rectum and vagina, as is shown in Fig. 189. If these fibers are separated from their lateral attachments to the rectum, the pelvic floor is weakened and the vaginal outlet relaxed. The rectum will, as it were, fall away from the vagina, so that the space occupied by the perineal body is increased in its antero-posterior diameter, providing the fourchette has not been torn. It is this sort of a deep perineum which is weak, and which undoubtedly has given rise to the too sweeping assertion that all deep peri- neums are weak, whereas shallow, short ones are strong. If the fibers of the levator ani are neither separated nor relaxed the INJURIES OF PERINEUM AND PELVIC FLOOR. 817 functional activity of the pelvic floor, as a whole, is preserved, whether the perineum be deep or shallow. While, then, it is true that very deep perineums may be weak, they are weak not because of the large quantity of areolar tissue in them, but rather because the muscles and fasciæ are separated from their median attachments. As the presenting part of the fetus impinges upon the pelvic floor during parturition, it forces the fibers downward and rolls them outward and forward from under the pubic arch. The pel- vic floor, in common with the entire parturient canal, is softened by the changes incident to gestation, and, as the head descends and recedes with each succeeding pain, the muscular fibers are gradually stretched and dilated until, in normal cases, the head is delivered without injury to the mother (Fig. 9). If there exist a disproportion between the size of the parturient canal and the FIG. 189. DIAGRAM OF VAGINAL OUTLET, SHOWING RELATIONS OF THE LEVATOR, Rec- tum, and VAGINA. (Kelly.) fetus which has to pass through it, or if the pelvic floor is not thoroughly relaxed before the fetus is expelled, injuries are almost inevitable. Forms of Injury.—Injuries to the pelvic floor resulting from childbirth may be divided into two classes: :- 1. Visible tears, varying from a slight rent of the fourchette to a laceration extending into the rectum. 2. Invisible or subcutaneous tears. Here the muscular fibers and fasciæ are either lacerated or over-stretched. This condition permits of great relaxation of the outlet, the injury being fre- quently unrecognized because of the fact that the injury is con- cealed by the mucous membrane. A slight rent involving only the mucous membrane at the fourchette is of frequent occurrence, especially in primiparæ, 52 818 A TEXT-BOOK OF GYNECOLOGY. and, except as it furnishes an avenue for the entrance of germs, is of little consequence. If it does not extend beyond the sphincter the pelvic floor remains unweakened. When the recto- vaginal septum is involved it may extend as far up the vaginal canal as the cervix; usually it is confined to the lower inch of the septum. Central perforation of the perineum is a rare injury, though it occasionally occurs. It is the result of faulty posi- tion of the presenting part, or of deformity of the pelvis which drags the head backward instead of forcing it forward under the pubic arch. FIG. 190. A C 0 نا A. Relation of levator, rectum, and vagina (diagrammatic). B. Same, showing deep tear separating levator fibers from rectum in right sulcus. C. Same, showing relaxation of outlet, separation on both sides. D. Same, showing tear into rec- tum; levator fibers not injured. (Kelly.) Invisible or concealed tears often extend up one or both vagi- nal sulci, beginning at the posterior columna rugarum (Fig. 190). One sulcus is usually more extensively involved than the other, the separation even extending as high as the cervix. The perineum may or may not be involved. These lateral injuries correspond to the axis of the vagina and, extending in the direc- tion of least resistance, separate the rectum from the levator ani muscle. The rectum itself is left uninjured. In those injuries extending through the recto-vaginal septum the muscular fibers of the pelvic floor are ordinarily not separated. (Fig. 190, D.) INJURIES OF PERINEUM AND PELVIC FLOOR. 819 Causes.-The various causes tending to produce laceration and relaxation of the pelvic floor are:- Occipito-posterior presentation and malpresentations in general; Excessive uterine contractions; Narrow and too acute pubic arch; Weakening of the perineum from syphilis ; Excessive rigidity, especially in elderly primiparæ; Obstetric operations, particularly forceps delivery. The use of the obstetric forceps oftener produces superficial injuries than concealed. Even in the hands of the most skilled obstetrician, tears more or less extensive in character, will every now and then result from its application. Nevertheless the concealed injuries are oftener due to long continued distention of the pelvic floor by the presenting part of the fetus than to the intelligent use of instruments. Spontaneous Reparation.-Nature, ever conservative, en- deavors in her own way to repair injuries resulting from child- birth. Thus, in relaxation from over-stretching of the fibers, the outlet is more or less completely closed by the levator fibers next beyond those which are injured. A constant spasmodic effort, when the patient is not at rest, is made by these fibers, though the contraction usually is insufficient to replace the natural support. In visible tears not extending into the rectum complete union will often occur if the parts are kept clean and in apposition. Usually, however, such union is not possible without surgical interference. If the parts do not heal in this way, granulations are thrown out and scar tissue is created at the site of the tear which often gives rise to distressing reflex disturbances. This, in a measure, serves as a substitute for the original tissue, the cicatricial mass affording a point of at- tachment for the muscular fibers which are perineum. a part of the In tears involving the recto-vaginal septum Nature is also able to do much to remedy the accident. If the rent extends into the anal border of the sphincter muscle only, subsequent cicatrization will prevent extensive separation. If the septum is involved higher up, the sphincter tends to contract at a point within the rent and 820 A TEXT-BOOK OF GYNECOLOGY. more or less control of the bowel is preserved. However, after a certain point is reached the sphincter no longer works concen- trically and the rectum is so separated as to destroy all retaining power. Results of Relaxation and Laceration of the Pelvic Floor. -Immediately after labor, it is impossible to recognize mere re- laxation. After the patient is up and about she will complain of indefinite bearing down pains and a feeling of insufficent support at the vaginal outlet. As time goes on this distress becomes more and more marked. The symptoms are particu- larly aggravated by being on the feet, especially if the patient is compelled to lift and do manual labor. In due time there is often developed prolapse of the vagina with cystocele, rectocele, and even enterocele. Uterine congestion and the various forms of displacement, especially prolapse, are not infrequently associated with relaxa- tion and laceration. In complete laceration there is inconti- nence of feces and gas. The formation of a cystocele in these instances is due to the intimate attachment of the bladder to the anterior vaginal wall. The bladder loses the support afforded by the pelvic floor and perineum which causes it to descend in the form of a pouch into the vagina. At first this is small, but as time goes on it increases in size until the tumor becomes sufficiently large to protrude from the labia. Because of the inability to completely empty the bladder, cystitis, dysuria, etc., result. The nature of the tumor can readily be determined by passing a sound into the bladder or by placing the patient in the genu-pectoral posture. A rectocele or recto-vaginal hernia is produced by the same causes which, acting in front, give rise to cystocele. As the rectum pouches into the vagina, it becomes filled with fecal matter, which is evacuated with difficulty. This gives rise to tenesmus, hemorrhoids, obstinate constipation, and even serious inflammation. The tumor varies in size from a simple protru- sion to one as large as an orange. The diagnosis is readily made by rectal exploration. Enterocele or entero-vaginal hernia, is caused by the descent of INJURIES OF PERINEUM AND PELVIC FLOOR. 821 a portion of the small intestines in such a way as to encroach upon the vaginal canal. It is oftener located posteriorly. The intestines in Douglas's pouch may gradually stretch this serous prolonga- tion, which, pushing before it the posterior wall of the vagina, may present at the vulva the form of a tumor. This condition is FIG. 191. 4596 A vertical section of the female viscera showing hypertrophic elongation of the cer- vix uteri with eversion of the vagina and descent of Douglas's pouch to the level of the anus. The peritoneal surface of the body of the uterus is covered with fibrous membranes, the result of peritonitis, and in its anterior wall are three small myomatous tumors. (Museum R. C. S. Photographed by the Author.) sometimes associated with hypertrophic elongation of the cervix (Fig. 191). The symptoms of enterocele are usually not dis- tressing. The diagnosis is made by rectal exploration and by the tympanitic character of the sound elicited upon percussion. It 822 A TEXT-BOOK OF GYNECOLOGY. is important to bear in mind the possibility of enterocele if the vaginal tumor is first discovered during labor. Strangulation at this time is not impossible and if the condition is mistaken for other forms of vaginal tumors, serious consequences might result from an incision. In all cases of doubt, capillary puncture and aspiration are wise precautions to observe before thrusting a knife into the tumor. In cases of relaxation inspection will show that even though the perineum is actually deeper than normal the ostium vaginæ is not properly closed. The anal cleft, instead of presenting as a sharp, deep furrow, is flat and shallow, and the anus drops backward instead of being drawn up under the pubic arch. As the finger is carried into the vagina the distinct transverse ridge of fibers, extending from one pubic ramus to the other, cannot be felt. The only resistance met with upon pushing the poste- rior vaginal wall backward is the large open muscular loop which rises low down on the pubic ramus, and passes around the rec- tum and vagina just in front of the coccyx. If the patient is upon her back, and the perineum is retracted with a finger in either vaginal sulcus, the anterior and posterior vaginal walls will roll out; in cystocele and rectocele the pouching is very marked. Or, if she be placed in Sims's posture, the ostium is not normally closed, but is sufficiently gaping to permit of the entrance of air. If the finger be now carried into the vaginal sulci the line of separation can be distinctly felt. In the erect posture the intra-abdominal pressure tends to force the pelvic contents from the weak outlet. There is usually more or less descent of the uterus connected with relaxation. TREATMENT. This resolves itself into— (1) Palliative; (2) Surgical. Palliative Treatment. The palliative treatment consists of those measures having for their object the relief of pelvic con- gestion and the temporary support of the uterus and vaginal walls-the hot douche, the glycerin tampon, and a properly fitted pessary, should there be uterine or vaginal displacement. INJURIES OF PERINEUM AND PELVIC FLOOR. 823 Elderly women, especially, often decline to submit to operative interference, and it is possible to keep them fairly comfortable by the various palliative measures recommended in Chapter X. Surgical Treatment-Primary Operation.-Recent superficial tears should be repaired at once. This will not only make a secondary operation unnecessary, but it closes one, and a very important avenue for the reception of septic matter. If the tear is a simple one, and does not extend into the sphincter, its closure is not in the least difficult, and any physician capable of assum- ing the responsibilities of an accoucheur ought to be able to repair it. The patient should be placed across the bed with her hips projecting over its sides. After washing away the clots and débris with a 1:4000 bichlorid solution, the surfaces of the wound, if at all irregular, are trimmed with scissors so as to make coap- tation perfect when they are brought together. I prefer silver wire for suture material. This is threaded into an ordinary straight perineal needle, which is carried through the tissues by means of a needle holder. From one to four sutures will be necessary, according to the extent of the tear. The first two sutures are buried in the recto-vaginal septum, and are entirely concealed. The third and fourth, if used, are introduced in such a way as to make their appearance within the vagina. If, how ever, the tear is more extensive and involves the posterior vagi- nal wall, sutures must be passed within the vagina so as to approximate the torn surfaces. The sutures are finally secured by twisting or by perforated shot, care being taken not to cause too great tension. The external sutures are entered about a quarter of an inch from the margin of the wound and are made to reappear at the corresponding point on the opposite skin surface. After the sutures are secured the knees are tied together. The sutures are left in from seven to ten days. If the parts are kept scrupulously clean, union will result in nearly every instance. The patient is allowed to urinate spontaneously, if she can do so, after which a 1 : 5000 bichlorid douche is given. If she cannot urinate spontaneously the catheter must be used. If the tear extends through the sphincter, the technique of the operation for its immediate closure will have to be modified. 824 A TEXT-BOOK OF GYNECOLOGY. Failures are here much more common than is the case in deal- ing with superficial injuries. The failure may be due to wound infection from fecal and lochial contamination; or to a bruised condition of the tissues which favors sloughing. it If the rent does not extend too far up the recto-vaginal septum, may be closed by passing the sutures according to the method FIG. 192. 6 5- 5 4 4 3 2 1 COMPLETE LACERATION. DENUDATION AND DISPOSITION OF THE SUTURES. (Emmet.) shown in Fig. 192. It is best, however, when the tear extends any distance into the septum, to pass a sufficient number of in- terrupted sutures from the vaginal and rectal sides of the wound to coaptate the surfaces nicely. Silver wire may be used for the vaginal surface, and silk or chromicized catgut for the rectal surface. These should be introduced about four to the inch. INJURIES OF PERINEUM AND PELVIC FLOOR. 825 In the after treatment of complete tears great care is necessary to prevent hardened fecal matter from stretching the parts during defecation. Secondary Operation. By this is meant an operation upon the perineum and pelvic floor after the parts have cicatrized- from two months to several years following the injury. All gran- ulations and inflammation at the site of the injury have disap- peared, and in order to restore the parts to their normal condition, raw surfaces must be created, either by denudation or by flap- splitting. There are certain general measures which should be attended to previously to any of the secondary operations upon the peri- neum and pelvic floor. It is not wise, especially in complete lacerations, to operate while the patient's health is greatly de- preciated. Unless the indications for immediate reparation are imperative, sufficient time should be taken to build up the general system. In incomplete lacerations, the bowels should be thor- oughly emptied by a cathartic twenty-four hours before the operation and the lower bowel washed out by an enema two or three hours before the patient is placed upon the operating table. She should be instructed to make a final effort to evacuate the bowels just previously to taking the anesthetic. Unless this last precaution be taken, water will be left behind which, together with the liquid contents of the lower bowel, will be expelled during the operation, much to the annoyance of the surgeon. When the recto-vaginal septum is involved, a longer time should be taken in order to insure complete emptying of the intestinal canal of all fecal and scybalous matter. A cathartic should be given every day for at least three days previously to the time set for the operation. The patient should, during this time, live almost entirely upon liquid food. The parts should be kept clean by antiseptic vaginal douches. For the enemata a boracic acid solution should be used. General anesthesia is advisable in nearly all cases. Unless ether is counter-indicated because of some kidney or lung lesion, it is preferable to chloroform owing to its greater safety. In superficial rents, and particularly if the patient is not very nervous, it is entirely possible to operate with but little pain 826 A TEXT-BOOK OF GYNECOLOGY. under the hypodermic use of cocaine. Occasionally, patients are met with who dread the anesthetic more than the operation. As a rule, however, general anesthesia is advisable. Immediately before the anesthetic is administered, a large hot vaginal bichlorid douche is given, for its hemostatic as well as its antiseptic effect. FIG. 193. *G TIE MANN=CO. SIMS'S SHARP CURVED SCISSORS. A large number of instruments is unnecessary. There should be a pair of scissors curved on the flat (Fig. 193); a pair of an- gular scissors (Fig. 160); two tenacula; two or three straight round perineal needles (ordinary darning needles about two inches long); two short curved needles; three or four catch- forceps; a needle holder; silk or chromicized catgut; Fritsch's FIG. 194. G.TIEMANN &COR יון EMMET'S Double Curved Scissors. or Sims's speculum; an irrigator; and a Kelly pad. The crutch is, in my opinion, entirely unnecessary. Emmet's right and left scissors curved on the flat are a convenience rather than a necessity. (Fig. 194.) Assistants.-Four assistants are necessary: two to support the patient's limbs, hold the speculum and assist the operator in various ways; one to aid with the instruments and sponges; and one to give the anesthetic. INJURIES OF PERINEUM AND PELVIC FLOOR. 827 Position of the Patient.-For all operations upon the peri- neum and posterior vaginal wall the lithotomy posture is the preferable one. In anterior colporrhaphy it will be necessary to utilize the Sims or semi-prone posture in order to expose the anterior vaginal wall. FIG. 195. FIRST STEP; DENUDATION BEGUN. (Skene). The character of the operation will depend upon the extent and nature of the injury. RESTORATION OF THE PERINEUM ONLY. Simple Denudation and Coaptation.-The assistants, one on each side of the patient, support the limbs which are flexed upon the abdomen, and with the unoccupied hands separate the labia 828 A TEXT-BOOK OF GYNECOLOGY. so as fully to expose the parts. The operator hooks a tenaculum into the muco-cutaneous surface of the left side at a point cor- responding to the upper margin of the rent (this is indicated by the scar tissue), and with a pair of curved or straight scissors dissects up a strip of mucous membrane at its junction with the skin surface and extending from this point to a corresponding point on the opposite side (Fig. 195). The tenaculum is now dis- carded and the strip of mucous membrane is held in the left hand. With a pair of scissors curved in the opposite direction another FIG. 196. SURFACE DENUDED AND SUTURES IN POSITION. (Thomas.) strip is removed from right to left. This is repeated until the denudation is carried to the required height; usually an area corresponding to that shown in Fig. 196 is denuded. The sutures (silkworm gut or silver wire) are now passed. I prefer for needles ordinary straight darning needles. They are inexpensive, readily penetrate the tissues, and, because of their shape, give rise to no hemorrhage. The lower suture is first introduced a short distance from the skin surface and made INJURIES OF PERINEUM AND PELVIC floor. 829 to reappear at a corresponding point on the opposite side of the wound. From three to five sutures, depending on the size of the denuded area, are ordinarily required. All except the last are entirely concealed and should be passed with the finger in the rectum as a guide so that the rectum may not be penetrated. In inserting the last suture it is better, instead of introducing it as is shown in the illustration, to pass it through the tissues at the upper angle of the wound on the left side, then carry it through the apex of the vaginal mucous membrane close to the point of denudation, causing it to reappear on the skin surface of the opposite side of the wound. When the sutures are tightened this will elevate the vaginal mucous membrane to the highest point of the wound, thus preventing the formation of a sulcus just above the newly-made perineum, which, by the re- tention of secretions, may interfere with union. During the entire operation constant irrigation is kept up with a 1:5000 bichlorid solution. It is rarely if ever necessary to do any- thing more than to temporarily compress spurting arteries in order to control the hemorrhage. The lower suture is first temporarily secured by two or three turns with the hands, and each succeeding suture from below upward is dealt with in the same way. After the parts are nicely coaptated each suture is seized in succession about two inches from the wound, in the blades of a wire twister (Fig. 95), and quickly twisted. There is danger of creating too much tension in doing this. The tension should be only great enough to hold the parts in nice coaptation, making due allowance in all cases for more or less swelling. It is a good plan, after the twisting, to shoulder the sutures with two tenacula. There should be but little pain after perineal operations, and when it occurs it is due to excessive suture tension. After the wires are twisted the ends are cut about two inches from the skin surface. The several ends are then twisted into one coil and protected either with absorbent cotton or a piece of rubber tubing. The limbs are brought together before the sutures are twisted. When the operation is completed the parts are carefully cleansed, wiped dry (the vagina being cleansed with a sponge held in a holder), sprinkled with iodoform, and a strip of iodoform gauze 830 A TEXT-BOOK OF GYNECOLOGY. packed into the vagina. An antiseptic pad should also pro- tect the newly-made perineum. The patient is then placed in bed with her limbs tied together. The buried animal suture may be utilized for coaptating the denuded surfaces instead of the outside sutures. If used, great care must be observed to prevent suture infection. Catgut should be chromicized in order to prevent too rapid absorption. The suture should not be permitted to touch any part of the FIG. 197. FLAP-SPLITTING OPERATION FOR INCOMPLETE LACERATION OF THE PERINEUM. (LINES OF INCISION.) (Munde.) patient or the table during the operation. A long catgut is threaded in a suitable needle, passed at the apex of the wound and tied. It is then reintroduced, grasping only a portion of the denuded surface, and interlooped. The sutures are passed about four to the inch until the lower angle or skin surface of the wound is reached. The catgut is pulled taut and held by an assistant as it is each time drawn through the tissues. It is next carried backward, including a still wider strip of tissue, INJURIES OF PERINEUM AND PELVIC FLOOR. 831 until finally the wound is completely closed, the last row approximating the mucous and skin surfaces. The chief advantage of the animal suture is that it does not require removal. To prove successful, however, the strictest antiseptic precautions must be observed in its use. Flap-splitting Operation.-This operation, now so popular with the larger number of specialists, was reintroduced by Law- son Tait and has received the imprimatur of his name. It is admir- FIG. 198. FLAP-SPLITTING OPERATION FOR COMPLETE LACERATION OF THE PERINEUM. (LINES OF INCISION.) (Munde.) ably adapted to those cases of simple laceration uncomplicated with pelvic relaxation, and complete lacerations involving the inferior extremity of the recto-vaginal septum. It possesses the great advantage of being quickly and easily performed. In order to prevent confusion I will describe under the present head the operation for both complete and incomplete tears. The patient is placed in the lithotomy posture, the index finger of the left hand is passed into the rectum for a guide, and 832 A TEXT-BOOK OF GYNECOLOGY. with a pair of angular scissors (Fig. 160) introduced into the left side of the recto-vaginal septum, the tissues are split from left to right (Fig. 197). Tait makes this median incision from a quarter of an inch to half an inch deep. If the laceration is an incomplete one the incision is carried up on either side to a point corresponding to the upper angle of the perineal rent. the recto-vaginal septum is involved in the tear it is also ex- tended downward and backward on both sides of the transverse incision to a point just beyond the edges of the sphincter ani muscle (Fig. 198). If The upper and lower flaps are now caught in two pair of catch- forceps or two tenacula, the upper being drawn upward and the lower drawn downward (Fig. 200). The sutures are passed from left to right and from below upward by means of a needle with fixed handle (Fig. 199), or, as I prefer, by straight, round darn- FIG. 199. G.TIEMANN & CO PEASLEE'S PERINEAL NEEDLES. ing needle. The latter makes a smaller wound and the bruising of tissue is much less than when a regular perineal needle is used. The sutures should be passed very close to the edge of the wound (Lawson Tait even recommending that the skin sur- face be left untouched). I agree with Mundé, however, that it is better to include a small portion of the skin surface, for by so doing coaptation is made more complete. After all of the sutures have been introduced they are secured in the ordinary way. The puckering of the posterior commissure, which inevi- tably results, is closed by a continuous catgut suture. I shall speak of my modification of this operation in dealing with re- laxations of the pelvic floor. This is a most ingenious, and, ordinarily, a most successful operation. For complete tears I think that it is unexcelled. Its superiority over the older method was most forcibly impressed upon me by a case sent to me by Dr. Sutherland of South Bend, INJURIES OF PERINEUM AND PELVIC FLOOR. 833 Ind. The recto-vaginal rent extended for at least two inches above the lower border of the sphincter; the operation was done six weeks after confinement, while the parts were yet subinvo- luted and exceedingly vascular. The hemorrhage was most pro- fuse, and it became necessary to tie a good many arteries with FIG. 200. FLAP-SPLITTING OPERATION FOR LACERATED PERINEUM. APPEARANCE OF WOUND AND INTRODUCTION OF SUTURES FOR BOTH VARIETIES. (Munde.) catgut which was evidently contaminated; at any rate, wound infection from some cause ensued. Sloughing occurred, but not until after the rectal and vaginal portions of the wound had united. The sloughing gave rise to an excavation in shape not unlike that shown in Fig. 200. This, in time, entirely filled in by granulation, and the patient recovered with perfect control of the sphincter. 53 834 A TEXT-BOOK OF GYNECOLOGY. Other Methods of Closing Complete Tears.-Various other operations, having for their object the reparation of complete tears, are now and have been for many years in vogue. Of these Hegar's, Hildebrandt's, Simon's, Baker Brown's, Emmet's, Freund's, and Goodell's are best known. In the first four the vivification is confined to the posterior vaginal wall and is median; in the last three it is bilateral and is made in the vaginal sulci. Of these various operations Emmet's is the most popular in this country, although, in my opinion, infinitely more difficult and unsatisfactory than the flap-splitting method. I will, however, for the sake of completeness, briefly describe it. Emmet's Operation. The area of vivification is well shown in Fig. 192. It represents a triangle on either side of the lacerated perineum. At the apex of the tear the two triangles are con- nected in the median line, the denudation being carried some three centimeters above the point of laceration. It will be seen by studying the figure that the median denudation represents the body of a butterfly and the lateral portions its wings. The parts are closed with silver wire of median size and the introduc- tion of the sutures is of great importance. The point of the needle armed with the first suture is introduced one centimeter and a half behind and outside the anus, on the left side. This is carried through the inferior part of the recto-vaginal septum and is made to appear on the right side of the anus at a corres- ponding point. The sutures must be guided by the left index finger in the rectum. Four or five sutures, one above the other, and all concealed within the vagina, are passed in this way. They are secured as in incomplete lacerations. If perfect coap- tation of either the mucous or the skin surface is not secured superficial catgut sutures may be introduced. The first suture is by all odds the most important one and must catch the ends of the broken sphincter muscle in such a way as to bring them into perfect coaptation when the suture is secured. The vivi- fication is carried only to the border of the rectal mucous membrane. If the rent extends more than two inches upward it may be closed by continuous or interrupted vaginal and rectal sutures. For the rectal suture chromicized catgut should be INJURIES OF PERINEUM AND PELVIC FLOOR. 835 used; for the vaginal suture wire, silk, silkworm gut, or chro- micized catgut, as the operator may select. In all operations for complete tears the operator must keep in mind the three objects to be attained, viz., the restoration of the perineal body; the closure of the rectal opening; and, finally, the restoration of the sphincter ani muscle. Of these three objects the last is by all odds the most important; unless com- plete union of the two ends of the severed sphincter muscle is obtained, failure, either partial or complete, is inevitable. FIG. 201. EMMET SIMON GISCHOFF HEGAR GRITSCH SUPERIMPOSED DIAGRAMS OF FRITSCH'S, HEGAR'S, BISCHOFF'S, SIMON'S AND EMMET'S OPERATIONS. OPERATIONS FOR RELAXATION WITH RECTOCELE AND CYSTOCELE. The various operations which have been devised to overcome relaxation of the pelvic floor, with rectocele, are shown diagram- matically in Fig. 201. These, embracing as they do various degrees and shapes of de- nudation, have all been devised for the purpose of picking up the relaxed tissues underneath the vaginal mucous membrane which 836 A TEXT-BOOK OF GYNECOLOGY. are responsible for the rectocele and for the deficient pelvic sup- port. They all, if properly performed, narrow the posterior vaginal wall. The breadth of denudation in all is greatest just within the vaginal outlet, which brings together at this point the lower border of the triangular ligament and the relaxed leva- tores ani muscles. Of the median operations I will describe Hegar's, as being the one oftener performed. Hegar's Operation.-The patient is placed upon her back with the thighs flexed upon the abdomen. The field of opera- tion is fully exposed by a Fritsch speculum passed underneath the pubes when the cervix is caught by its posterior lip in a stout tenaculum or volsella and drawn downward (Fig. 202). Two tenacula are fixed at the highest point of the peri- FIG. 202. HEGAR'S OPERATION. neal tear, one on either side, and retracted. This procedure will nicely expose the area to be denuded. With a scalpel two lateral incisions are made, beginning at the crest of the rectocele, which is usually just below the cervix, and extending down the sides to a point corresponding to the tenacula. The apex of the denuded area is caught in a third tenaculum and dissected from above downward. After a flap large enough to be held by the fingers is dissected up, the tenaculum is discarded and the tri- angular section is removed to the skin surface. This is then incised either with the scissors or the scalpel. Bleeding surfaces are temporarily caught in snap forceps. Constant irrigation is kept up during the operation. INJURIES OF PERINEUM AND PELVIC FLOOR. 837 The wound is closed by continuous catgut, or by inter- rupted sutures. If the continuous buried suture is used it is carried from above downward in successive rows until the parts are perfectly approximated. It is sometimes best to introduce one or two rows of buried catgut, bringing the mucous mem- brane together with interrupted silver wire sutures. After the vaginal surface is approximated the perineal wound is closed by silver wire sutures passed from without. Emmet's Operation.-In Emmet's operation the denudation is "posterior median in front and bilateral on either side of the FIG. 203. DENUDATION IN THE EMMET OPERATION. SUTURES PASSED. (Kelly.) columna," extending into one or both sulci for a variable distance. In Fig. 190, the manner in which the fibers connecting the levator ani and rectum are separated, is shown diagrammatically. The object of Emmet's operation is to utilize the vaginal sulci in such a way as more thoroughly to catch these fibers and bring them together. The operation is performed as follows:- An elliptical surface in each lateral vaginal furrow is de- nuded (Fig. 203). 203). This is accomplished by separating the labia and catching the crest of the rectocele in a tenaculum. Two other tenacula are hooked into the tissues near the car- 838 A TEXT-BOOK OF GYNECOLOGY. uncles on either side. If, now, the tenaculum which is hooked into the rectocele is pulled to the left, a triangle is formed which extends from this tenaculum to the tenaculum on the right side. A strip of tissue is removed between these two tenacula varying in width according to the extent of the denudation required. The crest of the rectocele is next drawn to the opposite side and a strip of tissue extending between this tenaculum and the one on the left side removed in the same way. This will leave an area of undenuded tissue between the crest of the rectocele and the skin surface, which is to be removed with a pair of curved scissors. As a result there will be left a denuded surface ex- tending into the sulci on either side. If the relaxation is greater in one sulcus than in the other, the denudation may be carried higher on that side. The manner of passing the sutures, devised by Dr. Emmet, is all-important, and is also shown in Fig. 203. Either silver wire, silkworm gut, or chromicized catgut may be used. In order to expedite the operation I use the continuous catgut suture, and cannot see but that the results are quite as good as when interrupted silver wire or silkworm gut is used. Begin- ning at the apices of the triangles they are passed transversely, the first not extending deeper than the mucous membrane. The subsequent stitches enter the vaginal mucous membrane close to the margin of the denudation and are passed deeply toward the operator, brought out at the bottom of the sulcus lower down than the point of entrance, reëntered near the same point and made to appear on the lateral vaginal wall close to the margin of denudation. Care should, of course, be taken not to injure the rectum. If interrupted sutures are used they may be secured as soon as passed. Usually from three to eight inside sutures will be sufficient to complete the operation. There will be left a small perineal surface unapproximated after the internal sutures are secured (Fig. 204). This is closed by two or three sutures passed from the outside just within the posterior commissure, not upon the skin surface. The Author's Operation for Relaxation and Rectocele. With or Without Laceration of the Perineal Body.—Tait's method of flap-splitting for incomplete tears is, as I have en- INJURIES OF PERINEUM AND PELVIC FLOOR. 839 deavored to show, a most ingenious one when the perineal body alone is to be built up. I have, however, been led to modify somewhat the technique given by Tait, Mundé, and others. As ordinarily performed there is left at the site of the newly created commissure a superfluous amount of tissue which is of no use FIG. 204. INTRODUCTION OF SUTURES IN EMMET'S OPERATION. THE VAGINAL SUTURES ARE TIED. (Thomas and Munde.) whatever for supporting purposes: the vaginal mucous mem- brane, being drawn downward without the ostium vaginæ, is liable to become irritated upon walking and during sexual con- gress. To overcome this I remove a small triangular portion of tissue at the upper angle of the wound and bring the oppos- 840 A TEXT-BOOK OF GYNECOLOGY. ing surfaces together with a chromicized catgut suture which is further utilized for the more perfect coaptation of the skin surfaces between the external wire sutures. This restores the fourchette to a virginal state as nearly as can be done by any operative procedure. If relaxation of the pelvic floor with rectocele is associated with the perineal rent, the flap-splitting operation, as ordinarily performed, will overcome neither the relaxation nor the rec- tocele. If the recto-vaginal septum is split high enough to bring together the separated underlying muscles and fascia and the wound is closed by external sutures alone, there will exist a degree of tension which will probably defeat the chief end of the operation; besides, the diaphragmatic pelvic muscles and fasciæ, instead of being restored to their normal relationship, are, when the external sutures are tightened, pursed in a most un- natural way underneath the pubic arch. Of course this opera- tion can be supplemented by any of the forms of posterior colporrhaphy which have been described, and in this way the rectocele and relaxation overcome. But when colporrhaphy is performed according to the method of Emmet, Hegar, Fritsch and others, it is a somewhat tedious operation, involves an un- necessary loss of tissue, and leaves behind avenues for septic infection. To overcome these several objections I have devised a method which, I believe, will more perfectly restore a relaxed pelvic floor than any yet devised. It is, indeed, an extended flap- splitting operation and was suggested to me because of the con- servative nature and extreme simplicity of the latter method of restoring the perineum. It is a combination of Lawson Tait's and Doleris's flap-splitting methods, of Schroeder's method of detaching the mucous membrane, and of Emmet's method of suturing. I proceed as follows:- The patient is placed in the usual lithotomy posture with an assistant on either side who retract the labia with the fingers. The index finger of the left hand is carried into the rectum to serve as a guide. The character of the transverse incision will depend upon the extent of the perineal rent. If the perineal body is not torn and the condition is one of simple relaxation, it is made with a pair of angular scissors close to the fourchette, INJURIES OF PERINEUM AND PELVIC FLOOR. 841 and is carried below the mucous membrane only (Fig. 205). At the muco-cutaneous surface this need not be more than half an inch in width, the separation being carried laterally as far as is necessary underneath the mucous membrane. If the perineal body is to be restored it is made exactly as in Fig. 197, with corresponding lateral incisions, except that the lateral incisions should not extend quite as high as is recommended in the orig- inal Tait operation. In either event the dissection, instead of FIG. 205. a FIRST STEP OF THE AUTHOR'S SUBCUTANEOUS OPERATION. a, b, Line of Incision. being extended into the recto-vaginal septum for half an inch only, is carried as high as the crest of the rectocele, even though this requires a separation two inches or more in depth. If the degree of relaxation is marked, it is extended laterally into one or both sulci; indeed, the dissection may be limited to one or both sulci, as in Emmet's operation, instead of making it posterior median. The separation may be done with a pair of blunt-pointed scissors, with the handle of a scalpel, or with 842 A TEXT-BOOK OF GYNECOLOGY. the finger. I think it best to use the finger only, for the tissues are easily separated, and by tearing them apart the hem- orrhage is reduced to a minimum; there is also much less dan- ger of penetrating either the rectum or the vagina, than when a cutting instrument is used. This step of the operation is facili- tated by catching the vaginal mucous membrane in a pair of forceps and drawing it upward; it can be completed in a minute's time. A stream of hot bichlorid should be kept playing upon the parts during the entire operation. A chromicized catgut suture twenty-four inches in length is threaded in a half curved needle three-quarters of an inch long and is passed through the vaginal mucous membrane, just above the apex of the wound, and tied at its middle. From this point it is carried down the sulcus of the left side as a continuous suture to the skin surface. This is handed to an assistant, the free end threaded into a curved needle and carried down the right sulcus in the same way. These two sutures are made to traverse the lower vaginal orifice transversely, meeting at the median line, along which, on either side, they are carried to the apex of the wound and tied. The three outer rows of sutures include a triangular area of mucous membrane, the base of which cor- responds to the vaginal outlet and the apex to the crest of the rectocele. The two median rows traverse this triangle from the center of the base to its apex. The sutures are interlooped, passed about four to the inch, and in the sulci are directed for- ward according to the method of Emmet (Fig. 203) except, of course, that they cannot be made to appear at the bottom of the wound. The tissues are, however, so lax that there is but little difficulty in turning the needle so as to imitate the direction of the Emmet suture. The median rows are passed only deep enough to catch the underlying tissues. If the skin and mucous membrane are not nicely coaptated by the transverse row they should be brought together with a continuous catgut suture.* * Latterly I have substituted interrupted silver wire sutures for the catgut. These are introduced through the vagina in such a way that the needle penetrates the rectal flap a little to the left of the median line, when it is carried around the left sulcus, is buried in the rectal flap and made to reappear at the upper and outer border of the right sulcus, when it again penetrates the vaginal flap near the point of entrance. INJURIES OF PERINEUM AND PELVIC FLOOR. 843 If the perineal body is torn through and requires building up, a triangular section is removed from the vaginal flap as in the modified Tait operation. This insures the removal of all cica- tricial tissue. The transverse sutures are passed above the apex of this section within the vagina, after which the wound is closed with from three to five sutures passed from the skin surface. This will result in a firm, solid perineum, the depth of which will depend upon the extent of the lateral incisions. For perineal sutures I prefer silver wire. I claim for this submucous method of perineo-colporrhaphy the following advantages:- 1. It is more simple and can be more quickly performed than can any of the colporrhaphies which necessitate the denudation of the vaginal mucous membrane, especially if the denudation is made lateral. 2. It conserves all tissue, except when a small triangle of mucous membrane is removed for the purpose of restoring the perineal body. 3. By conserving the mucous membrane the pelvic floor is greatly strengthened, while the rectocele is overcome perfectly. 4. The wound is entirely closed, except at the vaginal orifice, so that the possibility of septic infection is reduced to a min- imum. Let it be remembered that this is essentially a submucous opera- tion. The separated muscles and fasciæ are drawn together underneath the mucous membrane, though the sutures are passed through the vaginal canal. The mucous membrane becomes firmly adhered to the underlying structures, which it holds to- gether, after the parts are healed, as a broad strip of adhesive plaster holds together the gaping edges of a skin wound. It does not create within the vagina the redundant columns of mucous membrane as would seem to be the case upon first When the sutures thus introduced are tightened, the ends of the separated muscles and fascia will be drawn together underneath the vaginal flap. This brings the separated muscles and fascia together at the median line which is not the case when the sulci alone are utilized. From one to three vaginal sutures will be required and can be secured either by twisting or by perforated shot. 844 A TEXT-BOOK OF GYNECOLOGY. thought. On the contrary, it restores the vagina to nearly a virginal state, at the same time drawing the anus and the vaginal outlet toward the pubic arch more effectually than does any operation I have ever yet performed or seen performed. Anterior Colporrhaphy or Elytrorrhaphy.-When prolapse of the anterior vaginal wall, with cystocele, is at all marked it FIG. 206. STOLTZ'S OPERATION FOR CYSTOCELE. (Thomas and Munde). will be necessary to perform an operation having for its object the relief of the cystocele. Innumerable operations have been devised for this particular purpose, all of which involve more or less denudation and destruction of tissue. Thus Hegar denudes a surface the shape of an ellipse, which is very blunt at the upper extremity. Emmet recommends giving the denuded surface the INJURIES OF PERINEUM AND PELVIC FLOOR. 845 + form of a mason's trowel. Stoltz makes a circular denudation. The fact is, the form of denudation is not in the least important. It is necessary to incise freely the exuberant portion of the vagina. Pozzi includes in the jaws of two or three forceps the folds of mucosa to be removed, which extend about three centi_ meters from the orifice of the urethra to about two centimeters from the cervix. The tissue seized is removed with a pair of scissors, and after the forceps are detached the wound is brought together either with the continuous suture in superimposed rows, or with silver wire. Stoltz closes his circular denudation with a suture armed with a needle at each end, which he passes as shown in Fig. 206. This is a most satisfactory and expeditious way of closing the wound. During the dissection Stoltz de- presses the anterior vaginal wall with a sound in the bladder. In urethral prolapse Skene makes an incision through the vaginal mucous membrane on each side of the urethra, extend- ing from half an inch within the vulva to an inch or more upward and outward. The wound is closed with superimposed rows of buried catgut sutures by which the tissues below the vaginal wall are united to the fascia of the subpubic ligament. This operation involves no destruction of tissue. After-treatment of Colpo-perineorraphy.-The post-opera- tive care of all plastic cases is very important, if union by first intention is to be obtained. The patient is placed in bed with her knees tied together. If she can urinate spontaneously she is permitted to do so from the very first, after which a small 1 : 5000 bichlorid douche is administered. If she cannot urinate spontaneously a catheter must be introduced every six hours; in this event the cleansing douche is not called for. In those cases involving the recto-vaginal septum the greatest possible care must be observed in the management of the bowels. I think it is better to keep them confined with small doses of opium for the first four days. A cathartic is then given which is supple- mented by an enema of glycerin in order to insure complete liquefaction of the feces. During the evacuation of the bowels the nurse should watch the patient carefully and if any scybal- ous masses present at the anus, they should be dissolved by permitting a stream of warm sterilized water to play upon them. 846 A TEXT-BOOK OF GYNECOLOGY. In incomplete operations the bowels may be moved on the third day by an enema of glycerin and water. Subsequent evacua- tions are secured in the same way upon alternate days. If wire sutures are used they are removed from the seventh to the tenth day. There should be no persistent rise of temperature following perineorrhaphy or colporrhaphy if the case progresses normally. A persistent elevation usually indicates suppuration which, in the larger number of cases, is along the tract of some suture which is twisted too tightly; or, if the buried suture has been used, from wound infection. However, the temperature will often temporarily rise a degree or a degree and a half soon after the operation, but this quickly subsides and is purely reac- tionary. Should it remain persistently elevated the wound should be inspected, and if there is suppuration along the tract of one or more of the sutures, these should be removed; or, if swelling is excessive so that the pain is very great, the tension should be relieved by untwisting the sutures. Results. In incomplete colpoperineorrhaphy failure is rarely if ever met with. If it does occur, it is due either to faulty op- erative technique, to septic infection, or to improper after- or. treatment. In complete tears successes are not always met with, even in the hands of the best operators. However, since practising the flap-splitting method I have not met with a failure. Mortality.—A few cases are on record where death has re- sulted from tetanus and septicemia. As a rule, these operations are not dangerous and the few deaths which have been recorded were due to causes which might have set up fatal complications in any cutting operation. The operator should, nevertheless, bear in mind that the perineal region is particularly rich in lymphatics—hence the importance of strict antiseptic pre- cautions. A. INDEX. Abdomen, regions of, 95. Abdominal pregnancy, 794. Abscess, pelvic (v. Pelvic abscess), 480; of the vulvo-vaginal glands, 331. Adenitis, 65. Alexander's operation, 562. Amenorrhea, 230; varieties, 230; symptoms, 231, 232, 233; treat- ment, 234; electricity in, 160. Amputation of uterus for inversion, 582. Anatomy of the female pelvic or- gans, 30; development of the ovum, 30; external genitals, 31; muscles of the female perineum, 33; fascia of the pelvic floor, 35; deeper fasciæ, 36; perineal sep- tum, 38; pelvic floor dissected from above, 39; fascial coverings of muscles of pelvic floor, 41; peri- toneum, 43; ligaments of uterus, 45, 47; peritoneal pouches, 49; pelvic cellular or connective tissue, 50; uterus and annexa, 51; Fallopian tubes, 53; ovaries, 54; vagina, 54; bladder, urethra, and rectum, 55; ureters, 56; blood- vessels and lymphatics, 57. Anesthesia as a hystero-neurosis, 198. Angioleucitis, 65. Angioma, urethral venous, 511. Anomalies of secretion and excre- tion, 204. Anterior colporrhaphy, 844. + Anteversion and anteflexion, 547; diagnosis, 547; treatment, 550; pessaries in, 551. Antisepsis in gynecology, 170; the agents employed, 173; the opera- tor and assistants, 173; the patient, 173; the operating-room, 175; the operation, 175; disinfection of instruments, 175; ligatures, 176; sponges, 177; drainage tubes, 177; tamponnement of perito- neum, 178; irrigation, 179; dress- ings, 180; preparation of gauze, 180; after-treatment, 181; cathe- terization, 181; care of drainage tube, 182; in ordinary gyneco- logical examinations, 182. Aphonia, reflex, 208; during meno- pause, 288. Areolar hyperplasia, 442; general considerations and pathology, 442; causation, 446; varieties, 448; symptoms, 449; physical signs, 450; differentiation, 450; prognosis, 451; treatment, 452; therapeutics, 459. Ascites, diagnosis of, from ovarian cyst, 693. Aspirator in diagnosis, 87. Asthma, reflex, 206, 207. Astringents and styptics, 147, 249. Atresia of the vagina, 370; of the vulva, 364. Atrophy of the labia majora and nymphæ, 321. Auscultation, 115. B. Bandaging, tight, after parturition, as a cause of disease, 24. Barrenness (v. Sterility and impo- tence), 306. Bartholinian glands, abscess of, 331; cysts of, 331. Bichlorid of mercury as a germi- cide, 173. Bimanual examination, 101. Bladder, anatomy of, 55; inflamma- tion of, 492, 498; mucous mem- brane cast off, 73; irritability of, 515; neoplasms of, 514; parasites of, 515; stone in, 513. Blennorrhagia, 378. 847 848 A TEXT-BOOK OF GYNECOLOGY. Blood supply of pelvis, 57; volume of, in menstruation, 292. Borax in dysmenorrhea, 275. Broad ligaments, cysts of, 669, 674. Bulbs of the vestibule, rupture of, 334. C. Calcaria iodid in fibroma uteri, 624. Calculus, vesical, 513. Cannabis Ind. in uterine hemor- rhage, 254. Carcinoma of the body of the uterus, 637; pathology, 637; symptoms, 637; physical signs, 637; pro- gress, 639; prognosis, 639; treat- ment, 641. Carcinoma of the cervix, 627; gene- ral considerations and etiology, 627; varieties and pathology, 629; symptoms, 631; physical signs, 632; differentiation, 633; progress of the disease, 634; prognosis, 635 ; cause of death, 636; palliative treatment, 641; therapeutics, 645: curative treatment, 646; vaginal hysterectomy for, 647; Pratt's operation for, 654; illustrative cases, 657. Carcinoma of ovary, 672, 676; of uterus, 627; of vulva, 339. Caruncles, urethral, 511. Case, record, 58; taking, 58. Catheter, use and care of, 181. Catgut, care in using, 176; prepara- tion of, 176. Causes of gynecological diseases, 17; inherited feebleness of consti- tution, 18; defects in or absence of development, 19; acquired feeble- ness of constitution, 19; deficient air and exercise, 20; improper dress, 20; exposure during men- struation, 21; improper care dur- ing and after parturition, 22; mari- tal irregularities, 26; reflex func- tional disturbance and nervous disorders, 24; development of new growths and malignant dis- ease, 27; uterine displacements, 27; inflammatory, 28; accidental, 28. Caustics, 148. Cellular tissue, pelvic, 50. Cellulitis and peritonitis (acute), 402; frequency and causes, 407 ; pathology, 409; symptoms, 412; physical signs, 415; complications, 416; differentiation, 417, 428; course, duration, and sequelæ, 419; prognosis, 420; treatment, 420; therapeutics, 424. Cervix, carcinoma of (v. Carcinoma of the cervix), 627; erosions of, 430; fibroid tumors of, 591; granular and cystic degeneration of, 430, 454; hypertrophic elonga- tion of, 448, 573, 813, 821. Cervix, lacerations of, 801; his- tory and general considerations, 801; frequency, 802; etiology, 802; varieties, 803; pathology, 804, symptoms, 805; differentia- tion, 806; prognosis, 806; treat- ment, 807; indications for trache- lorrhaphy, 808; trachelorrhaphy, 808. Change of life (v. Menopause), 280. Circulatory disturbance as a hystero- neurosis, 201. Climaxis, 280 (v. Menopause). Climaxis, hystero-neuroses during, 187. Clitoris, anatomy of, 31; atrophy of, 321; hypertrophy of, 321. Cocculus in dysmenorrhea, 276. Coccygodynia, 358; anatomy, 358; causes, 358; pathology, 359; symp- toms, 359; differential diagnosis, 360; treatment, 360; therapeutics, 361. Coition, painful, 68, 317. Coitus, causes interfering with, 310. Colpocystotomy, 502. Conception, prevention of, as a cause of disease, 26. Condylomata of the vulva, 338. Congestion of the ovary, 763. Congestive and inflammatory dys- menorrhea, 261. Conjoined manipulation, 101. Constipation, 125; diet in, 126; mechanical causes, 127; enemata in, 127; therapeutics of, 128. Constitution, acquired feebleness of, 19; inherited feebleness of, 18. Corporeal endometritis, 437. Corrosive sublimate as a germicide, 173. Cough, hysterical, 206. INDEX. 849 Curette in uterine hemorrhage, 250, 255. Cyst and abscess of vulvo-vaginal glands, 331. Cystic and allied diseases of the uterine appendages, 663, 673, 683, 702; classification, 663; symptoms, 673; course and termi- nation, 678; contingencies, 678; diagnosis, 683; differentiation, 686; diagnosis of small ovarian tumors, 699; tapping for diagnosis, 700; ovariotomy, 702, 724; illus- trative cases, 732. Cystic oöphoro-salpingitis, 743. Cystic polypi of the uterus, 619. Cystitis, acute, 492; frequency, 492; pathology, 493; etiology, 494; symptoms, 495;, differentiation, 495; treatment, 496; therapeutics, 503. Cystitis, chronic, 498; etiology, 498; symptoms, 499; treatment, 499; therapeutics, 503. Cystocele, 820, 844. Cysts, vaginal, 375; of Bartholinean glands, 332; ovarian, 663. D. Defecation, painful, 67. Degeneration, granular and cystic, of the cervix, 429; fungoid, of the endometrium, 212. Dermatoses, 212. Dermoid cysts of ovary, 666, 674. Development, defects in or absence of, 19. Diagnosis of bodies expelled from vagina, 73; physical, 77, 93, 105. Diarrhea, during menopause, 289. Diet in neurasthenia, 130. Dilatation of the urethra, 509. Dilators, uterine, 86. Dipsomania, during menopause, 288. Discharges, significance of, 70; path- ology, 70; table of comparison, 71. Disinfectants, 148. Divulsion in dysmenorrhea, 268, 270; during menopause, 287. Double touch, 101. Douche, vaginal, 138; indications for, 139; method, 139; counter-in- dications, 142; in uterine hemor- rhage, 247. Douglas', cul-de-sac, 49. Drainage, in abdominal section, 716; Mikulicz's method, 178; tubes, 177. Dress, improper, 20. Dysmenorrhea, 257; general con- siderations, 257; varieties, 258; symptoms and diagnosis, 259- 266; treatment, 267; electricity in, 162; therapeutics, 272; illustra- tive cases, 277. Dysmenorrheal membrane, 73. Dyspareunia, 317. Dysuria, from cellulitis, 414. E.. Ectopic pregnancy, 769; definition, 769; varieties, 770; etiology, 772; pathology, 774; symptoms, 776; diagnosis, 783; prognosis, 785; treatment, 786; electricity in, 789; technique of laparotomy for, 791 ; management of placenta, 792; vaginal extraction, 794 ; illustrative cases, 794. Electricity in gynecology, 152; gal- vanism, 153; faradism, 154; Franklinism, 155, 158; appara- tus, 155; galvanometer, 156; rheo- stat and electrodes, 156; general considerations, 157; electro-punc- ture, 159; in amenorrhea, 160, 234; in dysmenorrhea, 162, 267; in subinvolution, 164; in superinvo- lution and atrophy, 164; in ovar- algia, 165, 766; in chronic ovaritis, 166, 754; in chronic pelvic inflam- mation, 166, 754; in uterine dis- placements, 167; in endometritis, 168, 455; schema, 169; antisepsis in the use of, 183; in chronic diseases of the uterine append- ages, 754; in nervous prostration, 131, 134. Elytrorrhaphy, 844. Embryology, 30. Emmet's operation for complete tears of perineum, 834; for lacera- tion of cervix, 808; for relaxation of pelvic floor, 837. Encapsulated ovarian cysts, 721. Endocervicitis (v. Endometritis, chronic cervical), 429. 54 850 A TEXT-BOOK OF GYNECOLOGY. Endometritis, acute (v. Metritis and endometritis), 399. Endometritis, chronic cervical, 429; definition, 429; anatomy, 430; pathology, 430; etiology, 433; symptoms, 434; physical signs, 435; differentiation, 436; prog- nosis, 436; treatment, 452; thera- peutics, 459; electricity in, 168. Endometritis, chronic corporeal, 437; anatomy, 437; pathology, 437; causation, 438; symptoms, 439; physical signs, 441; differen- tiation, 441; prognosis, 442; treat- ment, 455; therapeutics, 459; illus- trative cases, 457; electricity in, 168. Endometrium, fungoid degeneration of, 437. Enteritis, membranous, 211. Enterocele, 820. Entero-vaginal fistula, 540. Epilepsy, reflex, 217. Episiorrhaphy, 535. Epistaxis, vicarious, 305. Epithelioma of cervix, 627; of vulva, 339. Ergotin in fibroids, 590, 625. Erosions of cervix, 430. Eruptions of vulva, 325. Erythema, in pelvic disease, 204. Etiology of gynecological diseases, 17. Eversion of cervical mucous mem- brane, 435; digital of rectum, III. Examination, antisepsis in, 182. External organs of generation, dis- eases of, 320, 342; deformities of the vulva, 321; eruptions, 325; vulvitis, 327; inflammation and abscess of vulvo-vaginal glands, 331; pudendal hemorrhage and hematocele, 334; pudendal hernia, 336; hydrocele, 337; edema of the labia majora and nymphæ, 338; neoplasms of the vulva, 338; dif- ferentiating table, 341; pruritus vulvæ, 342; hyperesthesia of the vulva, 349. Extra-uterine pregnancy (v. Ectopic pregnancy), 769. Exudations, pelvic, 410, 415. F. Fallopian tubes, anatomy of, 53; diseases of, 737, 754. Fasciæ, pelvic, 35, 36. Fecal fistulæ, 537. Fibro-cystic tumors of the uterus, 613; symptoms, 613; treatment, 614. Fibroid tumors of the uterus, 583, 599; definition, 583; pathology, 583; varieties, 583; number, size, and location, 584; structure, 585; degenerative changes, 587; of the cervix, 591; etiology, 591; symptoms, 593; physical signs, 595; progress and termination, 597; prognosis, 597; palliative treatment, 599; surgical treatment, 600; enucleation in submucous fibroids, 601; oöphorectomy for, 603; laparotomy for, 603; man- agement of pedicle, 605; compari- son of extra and intraperitoneal method, 609; myomectomy, 609; vaginal hysterectomy for, 610; removal of during pregnancy, 610; therapeutics, 624. Fibrous polypi of the uterus, 615. Fissure of the urethra, 510. Fistulæ, fecal, 537; vesico-vaginal, 518; uretero-uterine, 533; uretero- vaginal, 533; urethral, 534; recto- labial, 540; entero-vesical, 541; entero-vaginal, 540. Fistulæ, recto-vaginal, 537; symp- toms and diagnosis, 537; physical signs, 538; prognosis, 538; treat- ment, 538. Fistulæ, urinary, 518; varieties, 518; pathology, 518; etiology, 519; symptoms, 520; physical signs, 521; prognosis, 521; treat- ment, 522; operation for, 523; after-treatment, 529. Flap-splitting operation, 533, 831. Flexions of uterus, 547, 554. Flow, retention of, 233. Follicular degeneration of cervix, 429, 454. Fossa navicularis, 32. Fourchette, 32. Franklinic current, application of, 158. Fungoid degeneration of endome- trium, 437. G. Galvanism, 153; in amenorrhea, 160; in dysmenorrhea, 162, 267; INDEX. 851 in endometritis, 168, 454; in ova- ralgia, 165, 766; in chronic ovaritis, 166, 754; in chronic pelvic in- flammation, 166, 424; in sub- involution, 164; in superinvolu- tion, 164; in uterine fibroids, 600. Galvanometer, 156. Gastric neuroses, 209. Gastro-hysterorrhaphy,563; results and prognosis of, 564; illustrative cases, 566; for prolapse of the uterus, 575. Gauze packing in abdominal sur- gery, 178, 736; preparation of, 180. General pathology of gynecological diseases (v. Pathology, general, of gynecological diseases), 117; treatment of gynecological dis- eases (v. Treatment, general, of gynecological diseases), 124. Genu-pectoral posture, 91. Gestation, causes interfering with, 312; ectopic, 769. Glandular disturbances, reflex, 214. Gonococcus of Neisser, 74, 381. Gonorrhea, 378; causing pelvic in- flammation, 382, 739. Graafian follicles, 54. Granular degeneration of the cervix, 429, 454; vaginitis, 384. Guaiacum in dysmenorrhea, 277, 278. Gynecological dressings, 180; ex- aminations, antisepsis in, 182. H. Heart, disturbances of from pelvic diseases, 201. Hegar's operation for rectocele, 836; extra-peritoneal method of treat- ing pedicle, 605. Hematocele, extra-peritoneal, 472; etiology, 472; pathology, 473; symptoms, 474; treatment, 475; therapeutics, 478. Hematocele, intra-peritoneal, 463; etiology, 463; sources of the blood, 465; pathology, 466; symp- toms, 468; progress of the disease, 469; signs of suppuration, 470 ; diagnosis, 470; prognosis, 471; treatment, 475; therapeutics, 478. Hematocele, pelvic, 463; pudendal, 334. Hematometra, 368. Hematosalpinx, 743. Hematuria, 515. Hemorrhage, pudendal, 334. Hemorrhagic discharge from genital canal, 73. Hemorrhoids, vicarious discharge from, 304. Hermaphrodism, 376. Hernia, pudendal, 336; entero-vag- inal, 820; recto-vaginál, 820. Hydatids, 73. Hydrastis Can. in uterine hemor- rhage, 254; local use of, 145. Hydrocele, 337. Hydrosalpinx, 743. Hymen, anatomy of, 32; double, 374. Hymen, imperforate, 365; anat- omy, 365; symptoms, 365; treat- ment, 366. Hymen, persistent, 369; treatment, 370. Hyperemia, forms and sequelæ of, 120. Hyperesthesia of the vulva, 349; treatment, 350; therapeutics, 351. Hyperesthesia as a hystero-neurosis, 192; of the internal os, 283, 287. Hyperplasia, areolar, of the uterus, 442. Hypertrophic elongation of the cer- vix, 448, 573, 813, 821. Hypogastric region, pain in, 61. Hysterectomy for uterine inversion, 582; for uterine prolapse, 575; for uterine cancer, 646. Hysterical joint, 196; paroxysm, 223. Hystero-neuroses, 184, 192, 209; definition, 184; general considera- tions, 185; forms of, 186; physio- logical, 187; diagnosis, 189; prog- nosis, 190; symptomatology, 192; hyperesthesia, 192; anesthesia, 198; clonic and tonic spasms, 199; paralyses, 200; circulatory distur- bances, 201; anomalies of secre- tion and excretion, 204; disorders of respiration, 205; gastric neuro- ses, 209; intestinal neuroses, 210; disorders of the skin, 212; glandu- lar disturbances, 214; disorders of the nervous system, 216; epilepsy, 217; the hysterical paroxysm, 223; therapeutics, 225. Hystero-psychoses, 216. 852 A TEXT-BOOK OF GYNECOLOGY. Hysterorrhaphy for retro-displace- ments, 563. I. Imperforate hymen, 365. Impotence and sterility, 306. Improprieties of dress as a cause of disease, 20. Imprudence after parturition as a cause of disease, 22. Incision of the cervix in uterine fibroids, 600. Incision of the external os in cervi- cal endometritis, 454. Incomplete ovariotomy, 720. Indigestion, 124. Inflammatory diseases of uterine appendages, 737, 754; general considerations, 737; classification, 738; non-cystic oöphoro-salpingi- | tis, 739; cystic oöphoro-salpingitis, 743; pathology, 750; progress and termination, 752; prognosis, 752; treatment, 754; salpingo-oöphor- ectomy for, 755; illustrative cases, 758. Inhaler, Junker's, 88. Injuries due to parturition, 801, 815. Insemination, causes preventing, 308. Inspection, 110. Instruments, care of in gynecologi- cal examinations, 182. Interstitial pregnancy, 798. Intestinal neuroses, 210. Intestines, prolapse of, 570, 820. Intra ligamentous ovarian cysts, 721. Intra-peritoneal pregnancy. 794. Inversion of the uterus, 576; etiol- ogy, 576; symptoms, 578; physical signs, 579; termination, 580; treat- ment, 580; manual reduction, 580; reduction by taxis, 581; reduction by gradual compression, 581; am- putation for, 582. Iodoform gauze for peritoneal tam- ponnement, 178; preparation of, 180. Irremovable ovarian cysts, 720. Irritable bladder, 515; urethra, 513. K. Kidney, mucous membrane of pelvis cast off, 73. Kleptomania during menopause, 288. Knot, Staffordshire, 715. Kolpokleisis, 535. L. Labia, majora and minora, 31. Labia majora, hypertrophy of, 321; atrophy of, 321; phlegmonous inflammation of 330; edema of, 338. Lacerations of cervix (v. Cervix, lac- erations of) 801. Laparotomy for fibroids, 603. Lead poisoning as a cause of menor- rhagia, 240. Leucorrhea (v. Discharges, signifi- cance of), 70; vicarious, 302. Levatores ani in relaxation of pelvic floor, 816. Ligament, vesico-uterine, 45- Ligaments, broad, 47; cysts of, 669. Ligaments, round, 47. Ligaments, utero-sacral, 47 ; con- traction of as a cause of dysuria, 68, 414. Lister's, Sir Joseph, clinic, 171. Liver, reflex disturbances of, 214. Local applications, 142; alum, 147; belladonna 147; boracic acid, 148; boro-glycerid, 143; calendula, 145; carbolic acid, 146; caustics, 148; chloral hydrate, 147; conium mac, 147; eucalyptus glob., 148; gly- cerin, 143; hydrastis Can., 145; iodin, 143; iodoform, 148; iron, 147; opium, 147; tannin, 147; treatment of gynecological dis- eases (v.Treatment, local, of gyne- cological diseases), 138. Local lesions which cause reflex symptoms, 119. Lower extremities, pain in, 65. Lumbar pain, 59. Lymphangitis and lymphadenitis, 65. Lymphatics of pelvis, 57. M. Malformations of external genitalia, 331; of vagina, 363. Mammæ, reflex disturbances of, 216. Marital irregularities, 26. Martin's operation for myomectomy, 609. Massage in nervous prostration, 133. Membranous dysmenorrhea, 265; milfoil in, 277. Menopause, 280; anatomical changes, 281; symptoms, 281; INDEX. 853 treatment, 284; therapeutics, 286; illustrative cases, 287. Menorrhagia and metrorrhagia (v. Uterine hemorrhages), 238. Menstrual blood, retention of, 233, 365. Menstruation, exposure during, 21; hystero-neuroses during, 187; painful, 66. Menstruation, physiology of, 226; theories, 227; source of hemor- rhage, 229; changes in endome- trium, 229; volume of blood in, 292; vicarious, 290. Mercury bichlorid as a germicide, 173. Metritis and endometritis (acute), 399; anatomy, 399; causes, 399; pathology, 400; symptoms, 400; differentiation, 401; prognosis, 402; treatment, 420; therapeutics, 424. Metritis, chronic (v. Areolar hyper- plasia), 442. Microscope in diagnosis, 74. Micturition, painful, 67. Moles, hydatidiform, 73, 75; fleshy, 74. Mons Veneris, 31. Morbid perspirations, 289. Muciparous follicles in the vagina, 378. Mucous discharge from genital canal, 71. Mucous membrane, cervical, anat- omy of, 430; of the fundus, anat- omy of, 437. Mucous polypi of the uterus, 618. Mundé's flanged speculum, 81. Myo-fibromata of the uterus, 583. Myomectomy, 609. Narcotics, 147. N. Neoplasms of bladder, 514; of the vulva, 338. Nervous and blood supply of pelvis, 118. Nervous prostration (neurasthenia), 129; symptoms of, 129; Weir Mitchell's treatment of, 130; diet in, 132; local treatment in, 134; therapeutics of, 135. Neuralgic dysmenorrhea, 259. Neurasthenia (v. Nervous prostra- tion) 129. Neuroses, the, 121, 184, 192, 209. New growths and malignant disease, development of, 27. Noegerrath on latent gonorrhea in the female, 382, 739. Non-cystic oöphoro-salpingitis, 739. Nott's speculum, 79. Nymphæ, atrophy of, 321; hyper- trophy of, 321. O. Obstructive dysmenorrhea, 262; di- vulsion in, 268. Offensive discharges from genital canal, 72. Oophorectomy for diseases of ap- pendages, 755; for uterine fibroids, 603. Opium in carcinoma uteri, 643 ; local use of, 147. Ovaralgia, 766; electricity in, 165, 766. Ovarian dysmenorrhea, 260; region, pain in, 60. Ovarian tumors (v. Cystic and allied diseases of the uterine append- ages), 663; adhesions, 681; carci- nomatous, 672, 676; causes of erroneous diagnosis, 685; con- tents of simple and multiple cysts, 666; course and termination, 678; curability of by internal medica- tion, 678; dermoid or cutaneous piliferous cysts, 666, 674; diag- nosis, 683; differentiation, 686; fibromatous, 671, 675; multiple cysts, 665; inflammation of in- terior of cyst, 680; obstruction of the bowel, 681: papillomatous, 668, 669, 674; pedicle of, 672; prognosis, 682; proliferous, 665; rupture of ovarian cysts, 680; sarcomatous, 672; simple cysts, 663; symptoms, 673; tapping for diagnosis, 700; terminations, 681; twisting of pedicle, 679. Ovaries, anatomy of, 54; congestion of, 763. Ovaries, neuralgia of, 766; diag- nosis, 766; symptoms, 766; treat- ment, 766, 767. Ovaries, prolapse of, 764; diagno- sis, 765; symptoms, 764; treat- ment, 765, 767. Ovariotomy, 702; abdominal inci- sion, 707; anesthetics, 707; ar- 854 A TEXT-BOOK OF GYNECOLOGY. rangement of instruments, 705; cleansing the peritoneum, 715; closing abdominal wound, 718 clothing, 705; drainage, 716; dressing the wound, 719; encap- sulated cysts, 721; general prin- ciples of abdominal section, 702 ; illustrative cases, 732; incomplete ovariotomy, 720; indications, 703; intra-abdominal manipulations, 711; management of adhesions, 713; preliminary details, 705; table, 704; tapping the cyst, 711; temperature of the room, 705; treatment of pedicle, 713; after treatment, 724; care of bowels, 726; care of drainage tube, 717; diet, 725; nurse, 724; pain, 726; position, 726; pulse and tempera- ture, 727; septicemia and peri- tonitis, 728; therapeutics, 731; tympanites, 728. Ovaritis, acute, 417; chronic (v. In- flammatory diseases of uterine appendages), 737; electricity in, 166. Ovulation, causes interfering with, 312; and menstruation, connec- tion between, 227. Ovum, diagnosis of, 73. P. Pachysalpingitis, 738. Pain, the significance of, 59; as re- gards location, 59; as regards function, 66; as regards posture, 68. Palpation, abdominal, 93. Papillary vaginitis, 384. Paralysis, hysterical, 200. Parametritis, 402. Para-uterine cellulitis, 402. Parovarium, 53; cysts of, 671, 675. Parturition, improper care during, 22. Pathology, general, of gynecological diseases, 117; nervous and blood supply of the pelvic organs, 118; how distant organs are involved, 119; nature of local lesion caus- ing reflex symptoms, 119; forms of hyperemia, 120; the sequelæ of hyperemia, 120; the neuroses, 121; how general symptoms are induced by local disease, 121; how local disease is induced by sys- temic disturbance, 122; tempera- ment and constitutional bias, 123. Péan's extra-peritoneal method of treating the pedicle, 606. Pelvic abscess, 480; pathology, 481; symptoms, 482; differentia- tion, 483; prognosis, 484; treat- ment, 484; illustrative cases, 489. Pelvic floor, 40; fascial coverings of, 41. Pelvic hematocele (v. Hematocele, pelvic), 463. Pelvic pouches, 49; cellular tissue, 50; inflammation (acute), 402; (chronic) electricity in, 166. Percussion, 115. Perineal septum (triangular liga- ment), 38. Perineorrhaphy, primary operation (v. Perineum and pelvic floor, in- juries of), 815. Perineum, muscles of, 33. Perineum and pelvic floor, injuries of, 815; general considerations and anatomy, 815; forms of in- jury, 817; causes, 819; spontane- ous reparation, 819; results, 820; palliative treatment, 822; surgical treatment, primary operation, 823; secondary operation, 825; flap- splitting operation, 831; Emmet's operation, 834, 837; Hegar's operation, 836; Wood's operation, 838; after treatment, 845; results, 846; mortality, 846. Peritoneum, pelvic, 43, 46. Peritonitis, acute pelvic (v.Cellulitis), 402; after laparotomy, 728. Pessaries, for anterior displacements of the uterus, 551; for posterior displacements, 558; for prolapsus uteri, 574; precautions in the use of, 553. 560. Phlegmonous inflammation of the labia majora, 330. Physical diagnosis, schema of, 94. Physical examination, 77, 93, 105; instruments for, 77-88; table or chair, 77: vaginal specula, 77; rectal specula, 83; urethral spec- ula, 83; cystoscope, 84, 85; uter- ine sound and probe, 85; tenac- ula, 86; Nott's depressor, 86; uterine dilators, 86; curettes, 87; dressing forceps, 88; Junker's in- haler, 88. Placenta, retained, 74. INDEX. 855 Placental polypi, 620. Platina, in dysmenorrhea, 275. Polypi of the uterus, 615; varieties, 615; symptoms, 620; diagnosis, 621; prognosis, 622; treatment, 622; therapeutics, 624. Polypi, fibrous and blood, 74; ure- thral, 512. Polypoidal endometritis, 619. Positions for examination, 89; dor- sal recumbent, 89; lateral, 90; latero abdominal, or Sims's, 91 abdominal, 91; genu-pectoral, 91 ; erect, 92. Posterior colporrhaphy, 835. Pratt's method of vaginal hysterec- tomy, 654. Pregnancy, ectopic (v. Ectopic preg- nancy), 769. Pregnancy, hystero-neuroses during, 187; removal of fibroids during, 610. Prevention of conception as a cause of disease, 26. Prolapse of the bladder, 569, 820; of mucous and submucous tissues of urethra, 507; of the ovary, 764; of the rectum, 569. Prolapse of the uterus, 568; etiol- ogy, 569; pathology, 571; symp- toms, 571; physical signs, 571; prognosis, 572; treatment, 572; hysterectomy for, 575; gastro- hysterorrhaphy for, 575; pessaries in, 574. Prolapse of the vagina, 569, 820. Pruritus vulvæ, 342; causes, 342; local applications in, 345: symp- toms, 344; treatment, 344; thera- peutics of, 348. Puberty, hystero-neuroses during, 187. Pudendal sac, 36; hematocele, 334; hemorrhage, 334; hernia, 336. Pulsatilla in dysmenorrhea, 273. Purulent discharge from genital canal, 71. Pyosalpinx, 743. R. Rectal specula, 114; touch, 100. Recto-abdominal examination, 103. Rectocele, 820. Recto-vaginal fistula (v. Fistulæ, recto-vaginal), 537. Recto-vesical examination, 104. digital Rectum, anatomy of, 55; eversion of, 111; prolapse of, 569. Reflex functional disturbance and nervous disorders, 24; symptoms, how induced, 119. Regions of the abdomen, 95. Repositor for replacing inverted uterus, 581. Respiration, disorders of in pelvic diseases, 205. Retention of menstrual blood from imperforate hymen, 365; of urine, 516. Retro-uterine hematocele, 463. Retroversion and retroflexion, 554; etiology, 554; pathology, 554; symptoms, 555; diagnosis, 555; prognosis, 556; treatment, 557; pessaries in, 558; Alexander's operation for, 562; gastro-hys- terorrhaphy for. 563. Rupture of the bulbs of the vestibule, 334. S, Sacral and coccygeal region, pain in, 65. Salivation as a hystero-neurosis, 205. Salpingitis, acute, 417; chronic (v. Inflammatory diseases of uterine appendages), 737. Salpingo-oophorectomy, 755. Sanious discharge from canal, 72. genital Sarcoma, of the ovary, 672; of the uterus, 639. Scanty menstruation, 230. Schemata: I. Causes of gynecologi- cal diseases, 17. II. Development of the ovum, showing successive changes following fecundation, 30. III. Discharges from genital canal, 71. IV. Diagnosis of bodies ex- pelled from vagina, 73. V. Meth- ods of physical examination, 94. VI. Electricity in gynecology, 169. VII. The hystero-neuroses, 192. VIII. Dysmenorrhea, 257. IX. Vicarious menstruation, 291. X. Causes of sterility, 306. XI. Dif- ferential diagnosis of pudendal abscess, hematocele, hydrocele, hernia, cysts of the Bartholinian glands, edema of labia majora and nymphæ, and neoplasms of vulva, 341. XII. Comparing in- 856 A TEXT-BOOK OF GYNECOLOGY. flammation of vagina, uterus and annexa, and peri-uterine tissues, 428. XIII. Classification of the cystic and allied diseases of uter- ine appendages, 663. XIV. Dif- ferentiating ascites from large ovarian tumors, 693. XV. Dif- ferentiating pregnancy from ovarian tumors, 690. XVI. Clas- sification of inflammatory diseases of the uterine appendages, 738. XVII. Of ectopic gestation, 770. Schroeder's intra-peritoneal treat- ment of pedicle, 608. Scirrhous cancer of cervix, 627. Seclusion and rest in nervous pros- tration, 130. Senile or adhesive vaginitis, 388. Septicemia after laparotomy, 728. Sexual hygiene during climaxis, 285. Sight, immediate, 110; external in- spection, 110; per speculum (vag- inal), III; rectal, 114; urethral, 115. Silk, preparation of, 176. Silkworm-gut, preparation of, 176. Simon's operation for fistula, 532; specula, 82. Simple vaginitis, 378. Sims's position, 91; speculum, 81. Sitting, painful, 68. Skene's self-retaining catheter, 522. Skin, reflex disorders of, 212. Sound, uterine (v. Uterine sound), 85, 105; use of, 105. Sounds, existing, 115; 115. roduced, Spasms, clonic and tonic, 199. Specific vaginitis, 378. Specula, vaginal, 78; Thomas's Cusco's, 78; Nott's, 79; Brewer's, 79; Goodell's, 80; Wood's, 80; Sims's, 81; Mundé's, 81; Emmet's, 82; Cleveland's, 82; Simon's, 82; Ferguson's, 83. Sponge holder, Wood's, 528. Sponges, preparation of, 177. Staffordshire knot, 715. Stem pessary, 270. Sterility and and impotence, 306; causes, 306; treatment, 314. Stoltz's operation for cystocele, 844. Stone in the bladder, 513. Stricture of the urethra, 506. Subinvolution (v. Areolar hyper- plasm), 442;` electricity in, 164. Superinvolution, electricity in, 164. Suppressio-mensium, 231. Sutures, preparation of, 176. T. Tait's flap-splitting operation, 831. Tampons, vaginal, 149; as a carrier of medicaments, 150; to control hemorrhage, 150, 248; in uterine and ovarian displacements, 150; to retain other bodies in utero, 151; after operations, 151. Tapping for diagnosis, 700. Taxis in inversion of the uterus, .580. Temperament and constitutional bias, 123. Tenacula, 86. Thomas's anteversion pessary, 552, 561; retroversion pessary, 558, 561. Thyroid gland, reflex disturbances of, 215. Tight bandaging after parturition as a cause of disease, 24. Touch, immediate, 93; palpation, 93; vaginal, 96; rectal, 100; ves- ical, 100; double, 101; conjoined manipulation, 101; recto-abdom- inal, 103; recto-vesical, 104. Touch, intermediate, 105; uterine sound, 105; vesical sound, 109. Trachelorrhaphy, 808; posture for, 808; denudation, 809; instru- ments, 808; after-treatment, 812; removal of sutures, 813. Treatment, general, of gynecological diseases, 124; indigestion, 124; constipation, 125; nervous pros- tration, 129. Treatment, local, of gynecological diseases, 138; the vaginal douche, 138; local applications, 142; nar- cotics, 147; disinfectants, 148; astringents and styptics, 147; caustics, 148; vaginal tampon, 149. Triangular ligament (perineal sep- tum), 38. Trillium in fibroids, 625. Tubal pregnancy, 770. Tubes, Fallopian, 53. Tumors, fibroid, 583, 599; ova- rian, 663. INDEX. 857 Twisting of pedicle in ovarian tumors, 679. Tympanites after laparotomy, 728. U. Ulceration of the cervix, 430. Uretero-vaginal fistulæ, 533; uterine fistulæ, 533. Ureters, anatomy of, 55; obstruction of, 555. Urethra, anatomy, 55; caruncles of, 511; dilatation of, 509; fissure of, 510; irritable, 513; malformation of, 506; polypi of, 512; prolapse of mucous and submucous tissues + of, 507; stricture of, 506; vascular neoplasms of, 511. Urethral fistulæ, 534; specula, 115. Urethritis, acute, 492; chronic, 498. Urethrocele, 509. Urinary fistulæ, 518. Urination, painful, 67. Urine, hysterical, 204; retention of, 516. Uterine displacements, electricity in, 167. Uterine hemorrhage, 238; general considerations, 238; causes, 238; treatment, 246; therapeutics, 252; illustrative cases, 254. Uterine inversion, 576. Uterine sound, 105; indications, counter-indications, and dangers, 105; method of employment, 106; turning, 107; information to be gained by, 108. Uterus, absence of, 19, 231. Uterus, anatomy of, 51; inflamma- tion of (v. Metritis and endometri- tis), 399, 429, 437; extreme thin- ness of, 781; supports of, 543. Uterus, displacements of, 543; general considerations, 543; varie- ties, 543; etiology, 545; symp- toms, 545. Uterus, lateral displacements of, 568; prolapse of, 568; inversion of, 576; fibroid tumors of, 583; polypi of, 615; carcinoma of, 627; sarcoma of, 639. V. Vagina, anatomy of, 54. Vagina, atresia of, 370; acquired, 370; symptoms, 370; physical signs, 371; prognosis, 371; treat- ment, 372. Vagina, double, 374; inflammation of, 378. Vagina, occlusions of, 363; symp- toms, 363; results, 363. Vagina, prolapse of, 569, 820. Vaginal cysts, 375. Vaginal hysterectomy for cancer, 646; for fibroids, 610; Pratt's method, 654; membrane, 73; cysts, 375; specula, 111; touch, 96. Vaginismus, 352; pathology, 352; symptoms, 354; treatment, 354; therapeutics, 357. Vaginitis, 378; anatomy, 378; varie- -ties, 378; treatment, 385; thera- peutics, 386. Vaginitis, senile or adhesive, 388; general considerations and his- tory, 388; diagnosis and prog- nosis, 393; etiology and pathology, 393; treatment, 395; illustrative cases, 395. Vaginitis, simple and specific, 378 ; causes, 379; course and termina- tion, 382; differentiation, 74, 381; pathology, 379; symptoms, 380; treatment, 385; therapeutics, 386. Vaginitis, granular or papillary, 384; symptoms, 384; treatment, 385; therapeutics, 386. Venous angioma, urethral, 511. Ventro-fixation for retro-displace- ments, 563. Versions and flexions of the uterus, 543. Vesical calculus, 513; parasites, 515; sound, 109; touch, 100. Vesico-vaginal fistulæ, closure by flap-splitting, 533: Simon's opera- tion for, 532 (v. Fistulæ, urinary, 518); operative treatment of, 523. Vesicular mole, 73, 75. Vestibule, 31. Viburnum op. in dysmenorrhea, 276. Vicarious menstruation, 291; schema of, 291; evidence which justifies a belief in, 295; theories, 296; conclusions, 298; treatment, 298; therapeutics, 299; illustrative cases, 301. Vomiting, reflex, 211; after lapar- otomy, 725. 858 A TEXT-BOOK OF GYNECOLOGY. Vulva, atresia of, 364; neoplasms of, 338; deformities of, 321; hyperes- thesia of, 349. Vulvar region, pain in, 65. Vulvitis, 327; treatment, 328, 329, 330. Vulvo-vaginal glands, anatomy of, 34; inflammation of, 331; treat- ment, 332. W. Watery discharge from genital canal, 72. White's repositor, 581. Wood's needle for vaginal hysterec- tomy, 650; operation for lacera- tion of the perineum, with recto- cele, 838; speculum, 80; sponge holder, 528; wire twister, 528. in UNIVERSITY OF MICHIGAN 2 100! כן! 1 3 9015 02012 3645