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IGMH Collection de microfiches (mohographtes) ./ Canadian Instituta for Hiatorical Microraproductiona / Inttitut Canadian da microraproductiona hiatoriquaa fTfdNilMl and Bibliographic Notas/ Nota* tadmiquas at bibliographiqiMs I ■ lh9 tott Tha Im tituta hat attamptad to obtain tha bast original copy availabla for filminfl. 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Les diuils de ^t exemplaire qiii sont peut-ttre uniques du point de vue bibliographiqui^^qui pauvent modifier june image reproduite. ou qiii peuventexiger une modification dans la mifthoda normala de f {Image sont indiquis ci-dessous. □ Coloured pages/ Pegas da couleur ^ '■_.•' □ Pages damaged/ ' Pages andommagia s □ PagM restored and/or Ifminated/ }^ Pages restaurias at/ou pellicultes Pegas discoloured, stained or foxed/ Page|dt*^Vr-*^ I ' ? i ■ * ♦•• ■rx Ti?, f' M- . 1^ ■■■•V' > \\ ,; . *• , -^r... ■ J6 ■ . ■ YALEDICTORY ADDRESS TO THE ON THEttJi EECEIVING THE DEGREET OF DOCTOR ^« Oi^ MEDICINE & SURGERY, _^- C«iferrei If €4if^atiti| 4tfc May, 18Mk BY A. FvHOLMESi M.D., Fkofeawr of Medicine^ afld Dean of the Medical Faculty. •V ^ GsMTLEMBir, — At t^^ close of our mutual labon, and befor^ we Vf^if^ the relation so leitg subsisting between iul let me address 4o you It few^ words. I have/said " sever relation ;** I do not mean sever our con-. nexidn7for that, 14iope, may become still closer by the new relationship in which we how are about to stand. When you first placed yourselves under our direction, ^ou had two objects in view — instruction ancl graduation — th% former as the means of attaining to the latter ; the latter as a testimonial of successful/pursuit of the former. One of tliese objects, viz., graduation, it was iu our/ own power to bestow ; the other required your active co-opention; for no matter what amount of instruction we had ^n our power to give, it would have been of little avail had not your minds been prepared aiid ready to receive it. Pursuing, then, the same object, whethe^ as inktruetors or instructed, we might naturally be expected to, and I trust fatve, become mutually interested in «ich other ; so that Vhile rov in after lifoi may look back with satbfiMtion on the period of study spent with us, and with kindly wishes fof*the prosperity of your alma mater, Wi may here- after, in Hearing of your eminence in your profession, rejcjice that yoa « Hail from McGill College.** I'he codise of stuciy which you have pursued is an arduous one. Four years, when looked forward to, seem a long period, but yojur own e'xpe-^ rience has taught you that it is by no means too long to conquer, the various topics comprised in a good medical education. A.nd yet, after all ybiir labor, whereunto have you attained 1 You hive only, as it / I A l'^/ ana repetition shall har^^S^^^ you «ce in the hancfebf yowTnk,« ' ^^ ^ ^ *'^ »a»ipulati«, which ■ -t teach ycm,but wiich^!;:^i\t^:.^^^^^^^^^^^^ ver^^rofth^e tool, with whichr^^^.^^ ^^^ ^' r^dly decide upon the remSrell7t*\^'^^ «°^W «, 4d a glance or two seemed to elZ Sm 1 " ^^r**' * ^^^ ^»»^ it looked like intuition. The who^^JiTe^t ""'' i*'^^ ^^°^'' -"^J^^*- mind without the labored o,^mtS S "'^.*° ^""^ "I*» ^» complicated question, and S^UTf ^?^""^ "^ '^^ »"t a experience has long ^go ta^hTmo h^uT T''''' """^ ««»««»«», I edlyinduetimet^chyoo. ^ """^'^^^ esUmt^ir^eri^'^Sii^r^ often conflicting opimons^Xrcl'; """"' T ""^ ' *^^ ^"^^ «««J ft has even been called dillC^^^ '^""*^"' P'°^^ «f ^hat. doubt^it sometimes is, andrdlTl^,t il^^Iff"™ "^^^^^^^^ feet. There are, however Jew b^n?., 'rL" ^°^^«dge becomes per- apply the appellation of « e^cT" it'' ""^^T^'^Se'o which weL af other sciences dependent on th J f^ T ^^^"''"^ "°^ *^« Portiolis serving of the n^^T^^^^^t^' «*" ^^^"^ '^^ "y*i»g de- in none other/ What bmnch of kl^^^ '"*°'" «ourded«ctions%nt Kit be a complaint that medict^^^^^^^ twoandthree\housandy"aS^^^^^ forbetLeen norsayth.sameofother\rLhes "Srt """it '"'^''^' ' "'^ ^« to the other Faculties of our ColleJe anS « t TV"'" ^^''^ ^»*««e wet Areyourfoundationsmo^rmorvo^r ^^"^''^"^'°«^^^ took at education in geneml, a ^u ™t' vh,' h ^^f ' "°" '*+''« ^ inmds ofmen ever sfn^e men wL„u ted „J?1 i^^** °«?»Piedthe we find it at the present day pu«ued of „ IT' 't*'°°»' "d yel do tl.c contrary, havi not the "n^ewllts" di^ "^?^^'^*'* ^^' «« - Jy of old established institu^ols, bt evel^^f the incapacity not V 'n^u f ■■'. ■w ^.3■ y^ * . ' ' J>ftfy readied rurnished with t proved them, ment, till time ulatioD which - our profession hich ttv'caii'* ■ nt and pefse- t the study of ttor could so « few hints lole suhje<;t. ^h upon his ^ 'eason but a I gentlemen, j ill undoubt- i yoik^iiould ' variM and 09f of ihat. ," which no comes per- iich we can he portions lything de- itctions,but ehaneing ? w between J may we M>nfi(|ence f off than ►re stable ? ?upied the fid yel do *asis. On pacity not 1 rules, m than a relations ; er its dic- i '^* talion, mi^xims rooted in the pr^juditoes and apparent interests of commu- nities are rapidly givibg way. Lgpk\ again, at" the gloriousnncertamty oth of then,, however, lUd^l'r^ f^'^ °» temperament , ' one asserting the Aipremacy of its kL2ri ' "r"**™ ^^ 'o«tine-the alter J the other, feirful of „nt fed Ton^^^^ " «ot condescend t^ track. Routine i»not the part o a «3^r'?^P^^^^^ '"^^^^n and directions should always have Tb^f f ^ "' ^^°~ ^^^^'°»» unfitted for emergenci^, Zf^LntW^T ''^ ^ ^'' ^ ""^"•^''"y ends to the treatment o/mere Z;^!^?^"^ ^1^1!^ ^^^ ' »' J have oAcn endeavoured to imwZ Z« ' 'l^'^^^Y mere naines. physician over the quack ex sZThXir^^' t^e inferiority of the / J. h6w little we acknowledged ( ^e have inuch igaoiance, we «loffi, and fas. improvement. >m this caiise t 'rti'udice of an ' ()f small pox ilarerroueoua ig them with . them. Yon occurrences; ids." Nothing , J; yet, often, ^ child may nost pertina- nakes them most flimsy rests on a w practice, loy difficult »te, because t confession from being Q declaring interpreted^ rknow. ^^ epossessfon ''y; and a iroachesto perament j utine— the lescend to he beaten 3 decisions manifestly 'cases; it re names, rityofthe with the . »titution;*% state of body, and circnmstances in which it^ was P!?ced^H»aTe also ^ often warned you not to suffer yourselves to be led away by the mere name of disease, so as to treat all cases coming under that name in the same manner ; but always to regard disease not only ns modified by the circumstances which attend it, but often requiring a treatment opposite to that which at another time might be most advantageous. Medicine- should be as far as our knowledge will allow a scientific study. I have alluded in some former remarks to the rapidity with which an old practitioner will understand the nature of a case an^ pre- scribe its appropriate remedies ; but it is not always so. Manythnea with most earnest attention are we obliged to scan the aspects of a case. Many timet do we cautiously balance the plans of treatment most ap- propriate. Qilen do we wait in anxious solicitude the effects of the me- • dicines we have thought necessary to prescribe. Wearesometimes un- able fo decypher the indkjations of disease. Often we are unable to fbresee the results of our treatment. The investigations required to treat a case ar« often extremely extensive. We must seek the n^edical history of the patient for years hock, even to his progenitors; also, his ha- bits and the circumstances in which he has been placed; all present symptoms must be examined and their importance analysed. Having thus obtained a knowledge of the disease, we have next to investigate in what way we shall be best able to remove it Here we have to weigh all the circumstances which make one plan preferable Jlo another, and here we are often led to treat the same disease at different times in dif- tehnt modes, «.«i»nfla«»«»a*io"» which sometimes requires severe deple- tion, while at others we uphold the strength with stimulants and wine. Gentlemen,— In the course which you have gone through, you have necessarily learned many things which wdfB elementary ; and many that seemed more directly practical ; and you were^led, perhaps, to look upon the former as meire steps for the attainment of the latter, and there- . fore to be disregarded when the purpose was fulfilled. Your conclu- ' sion, though in some respects conect, would, on the whole, be errone- ous and the examinations you have gone through will have shewn you that your professora required quite as much ekboiaUon in your elemen- tary as in your practical studies. I desire now to impress upon you that much of this elementary knowledge is of direct practical bearing, and must not be laid aside, as if its end was wholly attahied ; but must con- tinue to be cultivated and refireshed from time to time. Let us take, ex. grat., the department ef Chemistry. You are perfitctr ly aware that wit^iout a certain knowledjie of cheinical lawa apd com- binations, it is imi^ssible to get accurate notions ef many of thf (tuK- -I A for Ji./ ""*^" "» tho* much nf J ; ^ *' '* identical in •«>ti^ materials. """ *° *^" Pe«everance in the Je of 1°"' The H "1 ' "^ • ^^ noi^- , blood ««^ . ^ "«*"» removed thm..»i, «i. '*"''*«>» and have- wood, and consigned to their annmJ . ^'^ the same channel of ti,« process of wast^ o«vi . "I'P«>P'«»te emunctori*. rnT "® he^tt-ni ""V «>'<'• of there nortk-m °" .•""»"' lK"t,and enob. -*™e* as the change that ta W «il - ^ °*»**«t«>n quite the. and common fir<> ..i H»*es jnace m the «•«! * 'i""e me* ««m, which i, aftHM to d2l^ "" "*""»»■■ •"■de«tanjC rf ZJ at 0|)eratioiig of canhot be uii- » which, under ofthcseopera- Jhce to health. » that our food, is identical in igh necessary niMf and that (•at is Usually he toNo zealona ««e of noi^- V o/ our bodies nowledge to Wy, becomes the strength «» are aware through the d to nourish" »>andhave-^ »nnel of the » wonderful^ >newing us et not the ome being ^ ally. 'autiful il- 'mical ap- and enab- to enjoy dowzero, je. This !r certain fh every of union [uite the ^ r stoves itaneous : of that lat may i lich na- ture keeps up her fitcs in the body, the flues ofVhich are pcrln|is Uabl« to become over-heated by undue accumulatbn\of fuel, as weU asth* more visible ones which we run through our dwetiings. But you may say these examples, though striking prooft of the need ofchemistry to enable us to understand the fhnotionsof the healthy body, are not practical, inasmuch as they do not refer to the diseased body. They are highly important as physiological truths, but they aro ' not pathological. This is true, but if you understand not the physiolo- gicalj how'can you understand the pathological 1 Could you venture to undertake a nice operation^ of* surgery without knowing the parts amongst which you are to cut 1 So how could you venture to meddle with diseased organs, the elements of whose functions you are unac- quainted with? But I need not rest my argument on this ground. I can show you that changes which are strictly pathological can only be recognized by chemical manipulations, and being recognized, can only be remedied by chemical appliances. You have ail heard of the Humoral pathology, «r of what, in the not very grammatical though very expressive phraseology. ■ of the day, are palled blood-diseases. This humoral pathology, by the bye, furnishes a not' uhinstructive episode in the history of medicine. Received'as manifest truth folr many ages, it fell at last into disrepute, became the butt of ridicule to the moderns, and was referred to chiefly as shewing the absurdities of the ancient schools of medicine. | This once supposed " exploded dogma** has, however, again begun to raise its head, and counts among its abettors many of the best and safest of our practitioners ; and this change is comparatively recent, for it was several yean after I had completed my medical studies before this old doctrine began to reappear. My mind is apt to dwell4]pon this change as one evidence, among many others, of thAMBterfection of our boasted, reason, and of the propriety of using modc^imd cau^on in asserting e^ven the tiiosi generally received of its conclusions. It is true t|iat in the olden time the humoral pathology was but a speculation, though certainly a happy one ; it was not based upon expe- riment, the proper ground of philosophical deduction, and therefore fell, ^e humoral pathology of the present day may be expected to becomiS an ascertained fact, inasmuch as it is biased ^ot on hypothesis, but on multiplied experiment and observation. ,^ But to return. Blood diseases are so named because fhey consist ill an alteration in the materials of which the blood is mfide up. That flu^ consists, as youjinow, of certain constituents in certain proportions van* able within certain limits, without affecting health; but beyond these becoming less fitted for the performance of its normal duties; aBd,,bc- \,. -::T-"Tr3l (C^ < I ■.(,■ \ Into „gi tL °" •"^'«»' '••• c«i«S^of- """" ""«- . ' • • , ■• "*<•"« of rMkolo- '^ » :■•/■—- 0> >^ m ' ^'proport'tooa 'r tho notion^ •'»gfiHVi«, d lead to th« '^ue be ap. •"•d ao re^ 'ley loom ia 1 th? Work not unfte-" dfjrobably 'd practice, "nal Amc- ion of food the bloud UtaoofB of produced, ■^^lation/ 'thii new ba« Jonf f tend to « hither/ '>« poiAt »preciae >lWe it <^ised I for the e blood odiiced wjind itiiolo- gists are taking. 1 might niso call yuii to survey the now views taken of the {lathulugy of gout ahd rhcumutisni, as well as the whole tribe o( xymutic diMflses,as a'rcason for not neglecting chemical pathology, but I shall con^ne myself in this connexion to asking your attention to the glimmer of light which hus been thrown upoi) the nutureand prevention of Tubercle, that scourge ot' humanity under the form oT consumption, and dther allied maladies. This is conceded to he a blood disease, and seems t^ arise from deficient eloboration of the hutriCnt articles poured into the blood, and intended to be there ^developed into the nourishing mate- rial of the botly, but in some hitherto unkhown way perverted into the tubercular de|Mni't. Recently observed lUcts, aideU by minute •chemical and microscopical research seem to point to over, abundance in the supply of oxygen to the blood as a cause uf the developmeni of tubercle, while its ][)revention, if not cure, would seera to have some relation to the dim- inished arteriulization of the blood. ' But I must not omit to ppint out what may seem plainer evidence of the practical importance of chemical knowledge,.viz., the direct adminis- tration of medicines td produce certain chemical changes. You are, of course fumiUar with the class Of remedies which act entirely on, chemi- cal principles. They bear u part, indeed, in the classifications of materia medica — the antacids, the lithontriptics, the antidotesiiave always been known to act, not as vital but as chemical- agents, uni! they have long been, and still continue, in use to remedy what ^ may call the grosser chemioil diseases of the body. But the recognition of the blood-<£>rigin of diseases^and the itivestigution into the precise changes >vhich.consti- tute them, or, in other words^JSami their " proximate, causes," will lead, and has already led to the seurCh ufler remedies which have the pC'Wer of altering these, conditions. Many remedies which now we ejiiploy empirically, or which arer culled specifics^ we shall probably come to u^ in order to fulfil precise indicatious, and to induce particular chatiges. You all know how useful the tartrate of antimony is in' inflammation of the pulmonary tissue. It is generally used, but its mode of action is.aljtb generally unknown. But when yoit hear that it has been ascertained by-^ ' chemical experiment that antimony is potent in diminishing the quaii^ tity of fibrin in the blood, you will feel more satisfied in prescribing it, ^ tlian if you gave it empirically as du agent which you had found to bd useful. So, again, in regard to nitrate of^tash, which has been^ given in large doses as a ren^edy for rheumatism : it is a ppwerful .solvent of £brin, and'We know that in rheuioatism that element of the' blood' is larg^y increased. (The eflects of iron in ahgmenting the red corpuscles become evident by the pallor of disease giving way to the roseate hue •f hiealth. /=^j '*w ^"'•-, 'iff- •.-■ I have^welt ao long on chemistry, that I can bntilanco at another eUHnentary study, viz., Physiology, which you should not neglect^n the plea that It is not practical j for, as the chemistry of the body is liable to ' ^T ^®'*ff ®^' «> w i' of the physiology. The knowledge of healthy ■huctnre and function is indispensable to a knowledge of their disordered states, find furnishes assistance in our most practical researches. Let us ielect for an illustration the cell-theory of growth. I^ is well-establish- ^ttat, commencing in a cell of the simplest kind,. oar subsequent growth and fjill development is by multiplicatioh oCsuch cells and their varied modes of union and expansion. Now this #opld seem at first to be a fact curious and interesting in itself, but ha^g little bearing on medical practice j but when we look into the*nature of abnormal gro^hs, ««raally called tumors, we find their progress a copy of that of the wT^u""J'*'*"**.^°"*^^"^"^y°" physiological knowledge applica- ble to he diagnosis of such tumors. As the natural tissue possesses pe. ^harities m its cell structures, so do abnormal growths distinguish ttemselves by varieties in the appearance of their cells. Nothing can tterefore be of more practical benefit than to acquire facility in the use rfthe instrument by which alone such researches can be carried on~I meaiv the microscope. That instrument is no longer to be regarded by the physician as simply furnishing curious and important information as totheminutias of creation, bu< as a^valuable as^stant in obAinmg a practical knowledge of many of our common diseases. Indeed the re- salts of the iise of that.instrumentin giving precision to the diagno&is of several diseases are of the highest importance. But I shall aUude but to one of its discoveries, a very curioiw though not a pleasant one, the exis- tence of minute parasites, both vegetable and animal, both on and with- in our very textures; The existence of the larger parasites, such as the various worms and others that may be nameless, has been of course known in all ages, but the fact that vegetable growths occur upon our skins and withm our bodies, or that mibuteanimab in large numbers occupy at tomes our very flesh and blood, has been revealed only recently and trough the aid of the microscope. It is now known that one of the Houblesome diseases of the scalp known as scald head (favus) is a veg©. table itang^ growing on the spot j that another (porrigo decalvans) is produced lif a similar growth within the tubuli of the hair. Intractable «ses of disorder pf the stomach have been found owing to a minute lungiu (sarcinA ventriouli/Vowing within that organ. Cases have oc curred wheje the blood^on examinaUon was found loaded with animals dda. and others where microscopic woraos (trichina spiralis) occupied a MfffS portion of the muscular structure. I ^ve thus endeavored, and I trust sncoessfbUy, to impcen npoa your mm lose thai thro led( I ^r< /ou uies sun led{ hon the nee i J 11 nainda tlittt thd knowledge reeeived in the elementary classes cann«t kae its yalae even when 70a have acquired perfect acquaintance with that taught in the more advanced or practical departments ; but that through your future clinical career you will need the aid of (hat know- ledge which formed the first steps of your professional improvement. I had inteaded to have addressed to you some ethical remarks in re<- ^rd to your feelings and deportment towards your patients and towards /our brethren of the profession, as Well as to point oufaa a duty'to your- ^Ives that you should cultivate your talents, and use the opportuni- Aea you will enjoy for your own improvement, which will then be sure to result in the desire and efibrt to add to the general stock of know- ledge, but I forbear and shall conclude by congratubting you on the honorable position to which you have now attained, fl|| by lioping that* the avenue this day opened to you may lead to a long course of naefhk I to others, and of satis&ction and enq^nce to yourselves. . •. . ■'■■-. ■ . . ■-/ . ■ '. ■>tl '#. 1 MoosB, OwiBB k BtMfEmom, Pnattn, MontiMl. -*V-~-i<. \ :A= oBlV li.S ''^ '•' ■ ^'■'^ —1 ^■-- '■