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 ,. ;'!■»' •^''TT^T'i 
 
 
 
 ANAESTHESIA IN A CASE WITH DIMINISHED 
 BREATHING AREA. 
 
 BY 
 
 G. GOEDON CAMPBELL, B.So., M.D., 
 
 'itant Demonstrator in Mediofne, HoQill University, Assistant Physieiani Hontrsal 
 
 General Hospital. 
 
 Reprinted from the Montreal Medical Journal, July, 189b. 
 
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 ANESTHESIA IN A CASE WITH DIMINISHED 
 BREATHING AREA.* 
 
 By G. Gordon Campbell, B.Sc., M.D., 
 
 Assistant Demonstrator in Mouioine, MoOill University. Assistant Pliysioian. Montreal 
 
 General Hospital. 
 
 The patient, Mrs. S., was a middle-aged, slightly built woman, of 
 medium height, much emaciated, and suffering from an enormous 
 abdominal tumour. As I liad not seen the case until just before I 
 began to aniesthetise her, I had prepared to administer ether by 
 means of a Clover's inhaler. While making the usual explanations 
 about the effect of the ether, I noticed that her respirations were 
 extremely shallow and quicker than normal ; and on re(|Uesting her 
 to take several long breaths, in order to fill the bag before turning 
 on the ether, I saw that this was an impossibility. No effort on her 
 part increased the air capacity of the lungs as it was ah ady taxed 
 to the utmost limit. I then turned on tlie ether and gave it very 
 cautiously at first, with plenty of fresh air, not thinking it advisable 
 in this case to hasten the anaesthesia by shutting off the air. All 
 went well until there was about 20 per cent, of ether vapour in the 
 respired air, and then the breathing, which had been gradually getting 
 quicker, became rapid and laboured, and reminded me \'ery strongly 
 of the condition present during a bad attack of asthma ; violent efforts 
 at respiration and little or no air entering the chest. There was no 
 spasm in the air passages, and the patient was only partially 
 anassthetised, so, in order to remove any possible degree of asphyxia 
 which might be added to the effect of the ether, I gave it without 
 using the bag No improvement followed, and chloroform given on 
 a piece of stockinette stretched over a wire frame was sul)stituted. 
 The dyspn(Tea gradually passed off and the breathing, although con- 
 tinuing quick and shallow, was not laboured, the pulse, however, was 
 rapid and of small volume. Full anaesthesia was established in a few 
 minutes, and after the usual pi-eparation the abdomen was opened and 
 the growth removed. While the adhesions between it and the intra- 
 abdominal ctrgans were being separated, the usu 1 respiratory reflexes 
 were excited, and a condition of dyspna^a, similar but less pronounced 
 than that seen at the outset under ether, occurred. I had to request 
 the operator once or twice to cease his manipulations for a few 
 moments and allow the quickened respirations to subside. I feared 
 * Read! before the Montreal Medioo-Chirurgioal Society, April 19i 1896. 
 

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 to continue giving the chloroform while they were presen lest I 
 should give an overdose, and withdrawing it altogether for any length 
 of time would have allowed of partial recovery of the patient ; an 
 equally dangerous condition. The pulse had become much slower (80) 
 and was of very poor volume indeed when the tumour was removed, 
 eighty minutes after I began the anresthesia I then replaced the 
 chloroform with ether and continued the anaesthesia for an hour 
 longer with the Clover's inhaler. 
 
 In order to compare as far as possible the two agents, without 
 having a possible third factor, asphyxia, in the case, I gave six 
 breaths of pure air to every one from the bag. An almost immediate 
 improvement was noted in the patient's condition, the pulse became 
 quicker, increasing to 105, but was very much fuller, and more 
 forcible, although in sudden relief of abdominal tensions like this 
 the opposite usually occurs, the patient bleeding into her own abdo- 
 minal vessels. The respirations increased from 24 to 30 per minute, 
 and intra-abdominal reflexes of about equal intensity to those observed 
 Under chloroform were set up by further manipulations in the abdo- 
 minal cavity. Now, however, there was no interference with the 
 breathing, showing that the cause of the former dyspnoea had been 
 mechanical altogether. The immense size of the solid tumour had 
 completely filled up the abdominal cavity and pushed up the 
 diaphragm encroaching upon the area of the thorax. The dyspnoea 
 here was plainly due to the physiological effect of the ether absorbed 
 upon the respiratory centre, causing quickened breathing ; once the 
 mechanical cause of obstruction was removed, the increased respiratory 
 rate and increased depth of breathing caused no distress. The patient 
 made an exceptionally good recovery and had no after vomiting. 
 The chief interest in the case, apart from the comparison of the two 
 agents, lies in tlie fact that it shows a condition in which chloroform 
 should be selected in preference to ether as an anajsthetic. It must, 
 however, be borne in mind that in cases such as these, where there 
 is some interference with free breathing, the danger of accidents from 
 chloroform is very considerably increased. 
 
 
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