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With on-going changes in land use practices from conventional livestock farming to commercial, wildlife-based activities, the interface or interaction between livestock and wildlife is increasing. As part of the wildlife-based activities of ecotourism, breeding and hunting, game farmers are also exploring the utilisation of meat from hunted or harvested game. The expanding interface or increased interaction between livestock and wildlife increases the risk of disease incidence and the emergence of new diseases or the re-emergence of previously diagnosed diseases. The risk is not only related to domestic and wild animal health, but also to the occupational hazards that it poses to animal handlers and the consumers of game meat. This review endeavours to highlight the role that game plays in the spreading of zoonotic diseases to other animals and humans. Examples of zoonotic diseases that have occurred in wild animals in the past, their relevance and risk have been summarised and should function as a quick reference guide for wildlife veterinarians, ecologists, farmers, hunters, slaughter staff, processors and public health professionals.
The progressive expansion of game ranching as an extensive form of game farming on developed (fenced) land in southern Africa has resulted in ranching with endangered and/or rare species which can to a greater or lesser extent, be found in free community with livestock. In many parts of the world, farmers are changing from conventional livestock farming to commercial, wildlife-based activities such as ecotourism, which usually requires a wide diversity of frequently translocated species and adequate populations for tourist viewing (Bengis, Kock & Fisher 2002). With game becoming more valuable and therefore stocked at higher densities on smaller properties, disease prevention has become a very important aspect of game ranch management (Bester & Penzhorn 2002). A survey amongst South African game farmers revealed that 34.3% of these farmers are farming with both domestic and game animals (Bekker 2011). Skinner (1970) expressed concern regarding the dangers that game poses to domestic livestock by acting as reservoir hosts of pathogens of livestock which can cause epizootic disease and also that the handling and management of wild animals in relation to disease control is difficult. In support of this, Bengis et al. (2004) were of opinion that the abovementioned situations will probably enhance and intensify the wildlife-livestock interface and that the potential for ’cross-over‘ of diseases will increase. The cross-over of epizootic outbreaks represents a serious threat both to wildlife and, via reverse spill-over (‘spill-back‘), to sympatric populations of susceptible domesticated animals (Daszak, Cunningham & Hyatt 2000). Bengis et al. (2002) also indicated that foreign animal diseases cycling in livestock may cross the interface and infect wildlife. Wildlife therefore plays an important role in the spreading of transmissible animal diseases. In the United States, the presence of brucellosis amongst elk and bison in the Yellowstone National Park is considered a potential threat to domestic animals grazing in the park (Daszak et al. 2000). Godfroid (2002) was of the opinion that the development of the game farming industry has contributed to the re-emergence of brucellosis. Diseases such as malignant catarrhal fever (MCF) in wild herbivore species often show few clinical signs, but the disease is often deadly to cattle. According to Li et al. (1996), the viruses responsible for MCF are an important obstacle to the propagation of endangered ruminant species in the wild, in captivity, or on game farms. Although the Office Internationale des Epizooties (OIE) has declared that rinderpest has now been eradicated from the surface of the earth and that all 198 countries and territories in the world with rinderpest-susceptible animals are free of the disease (Food and Agricultural Organization [FAO] 2011), Gortázar et al. (2007) have pointed out that true multihost diseases that are regarded as eradicated are the worst, because a single spill-over from wildlife to livestock may have severe consequences for health and the economy. Rinderpest, for example, was eradicated in Nigeria in 1974 after the JP15 campaign, but was reintroduced between 1980 and 1983 into two states of Nigeria from infected cattle to wildlife, and this resulted in the loss of an estimated one million cattle and numbers of wildlife, of which 207 buffalo, 20 warthog, eight waterbuck and two bushbuck carcasses were recovered (Shanthikumar & Atilola 1990). Other examples of multihost diseases include bovine TB (Michel et al. 2006; Phillips et al. 2003), foot and mouth disease (Scoones et al. 2010) and avian influenza (Alexander 2000; Gauthier-Clerc, Lebarbenchon & Thomas 2007).Regarding zoonotic diseases, Cleaveland, Laurenson and Taylor (2001) then already indicated that 61% (868) of the 1415 species of infectious organisms known to be pathogenic to humans were of zoonotic nature. Some of these diseases can be transmitted through the consumption of animal-infected material or through the handling of such material (occupational disease). For the purpose of this review, human tuberculosis as a result of Mycobacterium bovis is briefly discussed. Several publications have already appeared on the prevalence of bovine tuberculosis in African wildlife and elsewhere in the world (e.g. Ayele et al. 2004; Michel 2002; Michel et al. 2006; Parra et al. 2006; Zieger et al. 1998). It was estimated by the World Health Organization (WHO) that M. bovis is the causative bacterium in 3% of all tuberculosis cases (WHO 1994a). Although high priority is placed on the meat inspection function at formally registered abattoirs to identify and remove carcasses with lesions of M. bovis from the food supply chain, asymptomatic animals or localised lesions could pass through the inspection system unnoticed (Van der Merwe et al. 2009). Poor and rural communities, furthermore, often obtain meat from uncontrolled and unregistered slaughter facilities where there is no meat inspection. Regarding game abattoirs, Bekker (2011) showed that in South Africa there are only a few registered game abattoirs, which are mostly used for export purposes, and that the real number and location of game slaughter facilities located on game farms are unknown to the relevant authorities and that almost no meat inspection is done on game farms. According to Cosivi et al. (1998), the intake of uninspected game meat may increase the risk of contracting tuberculosis. A number of authors such as Cosivi et al. (1995), Cosivi et al. (1998), De la Rua-Domenech (2006) and Thoen, Lobue and De Kantor (2006) have reported on human tuberculosis due to M. bovis globally. Some other examples of zoonotic diseases contracted by humans include a cutaneous anthrax outbreak that occurred in rural Paraguay through touching the meat of a sick cow (Harrison et al. 1989); an anthrax occurrence in Mashonaland East province of Zimbabwe due to handling, eating and drinking products of an infected animal (Mwenye, Siziya & Peterson 1996); brucellosis contracted by workers in meat packing plants (Taylor & Perdue 1989; White et al. 1974) and eating of caribou meat (Chan, Baxter & Wenman 1989); human trichinellosis which occurred in northern Italy after eating raw horse meat (Pozio et al. 1988); and the 2010 outbreak of Rift Valley fever (RVF) in South Africa where 172 cases and 15 human deaths after direct contact with RVF-infected livestock were reported by the national health department in South Africa (WHO 2010). Pavlin, Schloegel and Daszak (2009) indicated that the simplest way to minimise the risk of zoonotic disease is the reduction of opportunities for transmission of diseases from wildlife to humans. Although not clear for the neighbouring countries of South Africa, the survey amongst South African game farmers by Bekker (2011) indicated, however, that 41% of farmers with mixed farming systems have no control measures to prevent animal interaction in order to prevent disease spreading between game and domestic animals. Furthermore, specific gaps have been identified in game farming practices insofar as the establishment of written health plans, routine health inspections, screening for zoonotic diseases, provision of quarantine camps and record keeping of health and withdrawal periods as suggested by the GlobalGAP integrated farm assurance standard (GlobalGAP 2007). Furthermore, Liddell and Baily (2001) were of the opinion that the lack of records of animal health treatment undermines the ability to track the inputs used during this animal production stage of the supply chain. This desktop study provides a review of disease control mechanisms by the OIE, Angola, Botswana, Namibia, South Africa and Zimbabwe as well as a summary of the diseases associated with game occurring in the aforementioned countries and the relevance as well as the risk of cross-infections related to some zoonotic diseases that have occurred with game. This review should therefore function as a quick reference guide for wildlife veterinarians, ecologists, farmers, hunters, slaughter staff, processors and public health professionals.
Background
Animal hosts, vectors and the environment in a natural ecosystem are in a dynamic balance, with occasional pathogen emergence and impact, but disease is not frequent when compared to artificial or domesticated animal farming systems. The success of preventing disease on a farm revolves around the abovementioned balance. Pressures on the environment such as the expected increase in human population (1 billion in Africa from 2009 to 2050), rapid urbanisation in developing countries and the global demand for livestock products (requiring higher stock rates) cause multiple animal health problems (Thornton et al. 2009). As an example, both scenarios of overstocking and introducing animals into habitats that they are not adapted to (e.g. lechwe in the Free State Province of South Africa and gemsbok in high rainfall areas) are becoming more common in South Africa. These drivers may cause disease vectors to increase with host species not suited for their habitat (and vice versa) to be affected first by a disease (Bester & Penzhorn 2002).
‘Office Internationale des Epizooties’ controlled diseases
Internationally, the OIE is the intergovernmental organisation responsible for improving animal health worldwide and is recognised as a reference organisation by the World Trade Organization (WTO). With the consideration of international spread, zoonotic potential, significant spread in native populations and emerging diseases as criteria, the OIE keeps a list of so-called ’OIE listed‘ diseases for listing. All the countries relevant to this review (Angola, Botswana, Mozambique, Namibia, South Africa, Zimbabwe) are member countries of the OIE. It is required that all member countries will report to the OIE on incidences of any of the OIE listed diseases (OIE 2011a).
Disease control in Angola, Botswana, Mozambique, Namibia, South Africa, Zimbabwe
Policies and legislation normally form part of governmental animal health and food and meat control systems with the aim to prevent or control the spreading of disease to animals and humans. Regarding Southern Africa, Thomson and Penrith (2011) reported comprehensively on the animal health policy, legislation and trade in beef in the five participating states of the Kavango-Zambezi transfrontier conservation area (KAZA TFCA) which include Angola, Botswana, Namibia, Zambia and Zimbabwe and of which, Botswana, Namibia and Zimbabwe are neighboring countries of South Africa. Thomson and Penrith (2011) also list some trade related protocols of the Southern African Development Community (SADC) dealing with rules of origin for products to be traded between the member states of the SADC, sanitary and phytosanitary (SPS) rules, and technical barriers to trade (TBT). The following two tables provide non-exhaustive summaries of existing legislation in Angola, Botswana, Namibia, South Africa and Zimbabwe on the control of animal diseases and zoonosis (Table 1) and trade in meat and meat products (Table 2).
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Disease occurrence in game in Angola, Botswana, Namibia, South Africa and Zimbabwe
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Wildlife diseases have become more important in recent years and have led to an explosion of related knowledge (Gortázar et al. 2007). A non-exhaustive summary of zoonotic diseases that have occurred in wildlife animals in Angola, Botswana, Namibia, South Africa and Zimbabwe is therefore presented (Table 3).
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TABLE 1:
Summary of some legislation governing animal diseases in Angola, Botswana, Namibia, South Africa and Zimbabwe.
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TABLE 2:
Summary of some legislation governing trade in meat and meat products in Angola, Botswana, Namibia, South Africa and Zimbabwe.
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Overview of some zoonotic diseases associated with game
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Several worldwide outbreaks of animal related diseases such as bovine spongiform encephalopathy (BSE), avian influenza, RVF, et cetera and the associated media declarations have alerted consumers about the safety of meat in general. Because of these disease outbreaks, consumers are more informed and concerned about the safety and quality of meat products (Hoffman et al. 2005; Radder & Le Roux 2005). The industry has a moral responsibility towards the consumer in this regard. Gregory (2000) pointed out that the public puts their faith in the food authorities and the food industry to provide them with safe products. To achieve this, Gortázar et al. (2007) suggest that there should be close cooperation between multidisciplinary professionals such as wildlife ecologists, veterinarians and public health professionals. Regarding game meat production, certainly the game farmer, game hunting associations, processors (including those on farms), wholesale and retail markets and consumer interest groups should join in this multidisciplinary team. According to Bekker (2011), treatment of sick game animals is mostly done by veterinarians (59.5%) followed by trained farm staff (31.4%) and untrained farm staff (9.1%). From a veterinary health perspective, Blaha (1999) indicated that food animal practitioners play an important part in animal health management in general. In addition to veterinarians and other animal practitioners, veterinary public health practitioners can also play a role to ensure animal health and the provision of safe meat derived from slaughter animals to the consumer. Resulting from a desk top study, a non-exhaustive summary of the relevance as well as the risk of cross infections related to some of the zoonotic diseases that have occurred in the wild animals listed in Table 3 is also provided (Table 4).
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Emerging and re-emerging zoonotic diseases
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Sleeman (2006) raised a concern that the handling and eating of game meat by humans will expose them to new micro-organisms and contaminants and will result in the emergence of new diseases. Over the past years, emerging diseases have frequently hit the headlines, of which most have a zoonotic foundation. Emerging and re-emerging zoonotic diseases are those that are newly identified, newly evolved or have occurred previously, but have more recently shown an increase in incidence or expansion into a new geographical area, host or vector range (Bengis et al. 2004; Paulsen & Smulders 2004). Though not zoonotic, an outbreak of African swine fever (ASF) has for example recently occurred in the eastern parts of the Gauteng Province and the western parts of the Mpumalanga Province of South Africa. Both these areas fall outside South Africa’s ASF control area (GDARD 2012). Although the sources of these outbreaks are still unknown, the southward distribution and expansion of warthogs and tampans associated with the species could also contribute to the spreading of ASF beyond the borders of the ASF control areas (RMRDSA 2010). Although Daszak, Cunningham and Hyatt (2000) in their description of the relationship between wildlife, domestic animal and humans indicated that most emerging diseases impact on almost all groups, Pavlin, Schloegel and Daszak (2009) were of the opinion that most emerging infectious diseases are associated with wild animal zoonotic diseases. Infectious pathogens in wild animals as possible reservoirs have become increasingly important due to their substantial impacts on human health, domestic animal production, wildlife-based economies, wildlife conservation and global biodiversity (Bengis et al. 2004; Daszak et al. 2000; Paulsen & Smulders 2004). According to the FAO (2010), ± 60% of emerging infectious diseases of humans are zoonotic, of which 72% originate from wildlife. In addition, Christensen (1996) indicated that food of animal origin holds a threat to human health due to the diseases that it may transfer to humans and other animals.Risk factors influencing the occurrence of diseases in wild animals are based on (1) the movements or translocations of wild or domestic animals and animal products, (2) the result of wildlife surplus, (3) the changing agricultural practices to farming with wild animals that support the transmission of pathogens between wild and domestic animals, (4) host and vector expansion, (5) the association with ’spill-over‘ from domestic animals to wildlife populations living in the same proximity, (6) the relation to human intervention, (7) diseases with no overt human or animal involvement, (8) the increase in human population and their relation to local and international travel and contact with wildlife populations and their products, (9) adaptations of pathogens themselves to certain situations, (10) changes in the environment and ecosystems that increase the transmission of infectious agents through open-air breeding and (11) enhancement of diagnostic and epidemiological techniques which assist in early detection of emerging or re-emerging infective agents (Bengis et al. 2004; Daszak et al. 2000; Gortázar et al. 2007). Bengis et al. (2004) warned that the geographical expansion of pathogens and/or their vectors as a result of global warming and other associated climatic changes and the continued collision between human populations and wildlife in the human endeavour to advance into new habitats and ecosystems will increase the risk of new emerging diseases in years to come. They also pointed out that the most likely populations to be affected are those in less developed countries and poorer communities. Several opportunities exist for diseases to spread from one animal to another as they move around and associate with each other. Diseased animals, for example, die and are left to scavengers to clean, which in turn are infected and they spread the disease further. This process implies, however, that there may be some extent of dilution which will make the organisms responsible for disease less abundant and less likely to persist. Dilution occurs when other hosts in a community are also exposed instead of only being present in one highly competent reservoir host species alone (Begon 2008). Ogden and Tsao (2009) indicated that this method of dilution will result in fewer new infections and thereby reduce the basic reproductive number (R0) of the pathogen. In their study on Lyme disease, however, they also indicated that the extent of amplification or dilution of the disease is dependent on the mechanisms of completion, host contact rates and host resistance. Bengis et al. (2002) indicated that the most probable transmission mechanisms include (1) aerosols contaminating feed, water and range and (2) flightless vectors such as ticks, and winged vectors such as mosquitoes, and that one of the most important factors in disease transmission between livestock and wildlife is the creation of new interfaces. In addition to this, the increase in the distribution of game meat may also now be seen as a possible risk in the spreading of diseases.
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TABLE 3:
Summary of some zoonotic diseases reported to have occurred in game in Angola, Botswana, Namibia, South Africa and Zimbabwe.
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Disease surveillance and management
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From a study by Bekker (2011), there is evidence of minimal disease surveillance and management amongst game farmers. According to Paskin (1999) the early detection of disease increases the chance to arrest the disease prior to it causing damage. Detection requires that a surveillance system must be in place as required by the GlobalGAP integrated farm assurance standard (GlobalGAP 2007). Surveillance activities can be defined as:All regular activities aimed at ascertaining the health status of a given population with the aim of early detection and control of animal diseases of importance to national economies, food security and trade. (Paskin 1999) Disease surveillance is not a haphazard activity and therefore requires proper planning and techniques. A summary of aspects that Bengis et al. (2002) have provided as guidance in this regard is presented here (Table 5). From an economic perspective, it also makes sense to have proper prevention measures in place. The OIE (2006b) indicated in a report that dealt with an economical analysis of the costs of prevention versus the costs of outbreak, that the benefits accrued from improved prevention and control measures outweigh the costs of prevention and control investment. As an example, Tambi et al. (1999) proved that rinderpest control in Africa through the implementation of the Pan-African Rinderpest Campaign (PARC) in 1986 has been a wise public investment decision and that both producers and consumers gained from it economically.
This review shows that game plays an important role in animal disease spreading to other domesticated and wild animals and provides summaries of the occurrence of some zoonotic diseases in game in Angola, Botswana, Namibia, South Africa and Zimbabwe, current disease and meat (food) control legislation in these countries and the relevance as well as the risk of cross-infections related to some zoonotic diseases that have occurred with game. Of particular concern to game meat safety are the zoonotic diseases that can be transmitted through the consumption of meat and meat products. The consumer has to be safeguarded from possible infection (zoonosis) and therefore meat inspection of game carcasses is essential (Skinner 1970). However, as previously indicated, several of the zoonotic diseases are also an occupational hazard as farmers, farm workers, hunters, slaughter staff, veterinarians, processors, et cetera , can become infected whilst handling the animals or meat thereof.
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TABLE 4:
Summary of relevance as well as the risk of cross infections related to some zoonotic diseases that have occurred in wild animals.
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TABLE 5:
Factors to consider with disease detection and management.
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Pavlin et al. (2009) indicated that the simplest way to minimise the risk of zoonotic disease is the reduction of opportunities for transmission of diseases from wildlife to humans. To achieve this, Gortázar et al. (2007) suggested a multidisciplinary approach of wildlife ecologists, veterinarians and public health professionals. In addition, Oberem and Oberem (2011) pointed out the importance of disease-causing investigations carried out on dead animals by experts who will know how to prevent further spreading of the diseases, especially zoonotic diseases. In this regard, the animal disease investigation laboratories also play an important role as they can assist with the carrying out of routine investigations and surveillance programmes (especially notifiable, controlled and zoonotic diseases and research on animal disease and related issues) (Geering, Roeder & Obi 1999). The implementation of a comprehensive surveillance plan should be of critical importance to veterinary authorities (Gortázar et al. 2007) and will require innovative measures to improve vigilance (Bengis et al. 2004). In this regard, the South African Department of Agriculture, Forestry and Fisheries (DAFF), for example, have an epidemiology division whose mandate is contained in the Animal Diseases Act (Act No. 35 of 1984) (as amended) (South African Government 1984) and its main functions include (Ungerer 2008):• developing, analysing and auditing policies for the surveillance of animal diseases and diseases that can be transmitted from animals to humans • developing, analysing and auditing policies on disease reporting in the different provinces of South Africa • conducting risk assessments at a national level • acting as contact point for communicating risk and the occurrence of animal diseases in South Africa to foreign governments and international bodies • managing animal disease information and reporting thereof to the World Organization for Animal Health (OIE), Southern African Development Community (SADC) and the African Union (AU) • managing of animal disease information by using a Geographic Information System • managing of animal disease early warning systems (SADC, nationally and internationally) • ensuring that there are adequate government veterinary laboratory services at provincial level and elsewhere, for example in the Kruger National Park, and by
working in collaboration with the Onderstepoort Veterinary Institute of the Agricultural Research Council • enforcement of quality systems in diagnostic veterinary laboratories • auditing the enforcement of policy for reference laboratories. However, these measures will only be effective if wild game ranchers follow the correct procedures in contacting the relevant authorities. Bekker (2011), however, has illustrated negligence in certain farming practices and a lack of knowledge of farmers that may impact negatively on a country’s surveillance plan. To prevent a situation where farmers and other stakeholders may not place a high value on participating in achieving the main objectives of a surveillance plan, it is recommended that policy makers and law enforcers at all levels of government in collaboration with other wildlife industry stakeholders such as wildlife veterinarians, ecologists, farmers, hunters, slaughter staff, processors and public health professionals establish strategies to ensure that all stakeholders are adequately trained in the role that they play in the control of zoonotic diseases in game. Industry organisations such as farmer and hunting associations as ’bridging organisations‘ have a role to play with the provision of information or knowledge by (1) encouraging dialogue between governmental policy makers and industry, (2) acting as channels for policy makers to direct and apply new strategies at the industry-level, (3) assisting with the bottom-up flow of information at industry level and (4) providing platforms for information exchange (Berkes 2009; Tarnoczi & Berkes 2010). In addition, bridging organisations can provide a platform for trust building, sense making, learning, vertical and horizontal collaboration, and conflict resolution (Hahn et al. 2006). Meaningful knowledge is most likely to result in concept development, attitudinal change and positive behaviour.
We would like to thank the library and information services of the Tshwane University of Technology library for their support in obtaining information used in this review. This study was also partly funded by Stellenbosch University Overarching Strategic Plan Food Security Initiative.
Competing interests
The authors declare that they have no financial or personal relationship(s) which may have inappropriately influenced them in writing this paper.
Authors’ contributions
This manuscript forms part of a PhD study where the student J.L.B. (Tshwane University of Technology) was mainly responsible for the compilation of the review published on zoonotic diseases. L.C.H. (Stellenbosch University) was the first study promoter and P.J.J. (Tshwane University of Technology) was the second study promoter.
Alexander, D.J., 2000, ‘A review of avian influenza in different bird species’, Veterinary Microbiology 74(1–2), 3–13.
http://dx.doi.org/10.1016/S0378-1135(00)00160-7Alexander, K.A., Pleydell, E., Williams, M.C., Lane, E.P., Nyange, J.F.C. & Michel, A.L., 2002, ‘Mycobacterium tuberculosis: An emerging disease of free-ranging wildlife’, Emerging Infectious Diseases 8(6), 598.
http://dx.doi.org/10.3201/eid0806.010358, PMid:12023916
Ayele, W., Neill, S., Zinsstag, J., Weiss, M. & Pavlik, I., 2004, ‘Bovine tuberculosis: An old disease but a new threat to Africa’,
International Journal of Tuberculosis and Lung Disease 8(8), 924–937.
PMid:15305473
Begon, M., 2008, ‘Effects of host diversity on disease dynamics’, in R.S. Ostfeld, F. Keesing & V. Eviner (eds.),
Infectious disease ecology: Effects of ecosystems on disease and of disease on ecosystems, pp. 12–29, Princeton University Press, Princeton. Bekker, J.L., 2011, ‘A food safety plan for game meat in South Africa’, D. Tech thesis, Pretoria, Dept. of Environmental Health, Tshwane
University of Technology. Bengis, R.G., 2002, ‘State controlled diseases and game ranching’, in B.L. Penzhorn (ed.), November 2002, Symposium on game ranch planning and
management, pp. 60–64, Wildlife Group of the South African Veterinary Association, Onderstepoort, Pretoria. Bengis, R., Keet, D., Michel, A. & Kriek, N., 2001, ‘Tuberculosis, caused by Mycobacterium bovis in a kudu (Tragelaphus strepsiceros) from a
commercial game farm in the Malelane area of the Mpumalanga province, South Africa’, Onderstepoort Journal of Veterinary Research 68(3), 239.
PMid:11769357
Bengis, R.G., Kock, R.A. & Fisher, J., 2002, ‘Infectious animal diseases: The wildlife/livestock interface’, Scientific and Technical Review (OIE)
21, 53–65. PMid:11974630
Bengis, R.G., Leighton, F.A., Fischer, J.R., Artois, M., Mörner, T. & Tate, C.M., 2004, ‘The role of wildlife in emerging and re-emerging
zoonosis’, Scientific and Technical Review (OIE) 23(2), 497–511. PMid:15702716
Berkes, F., 2009, ‘Evolution of co-management: Role of knowledge generation, bridging organizations and social learning’, Journal of Environmental
Management 90(5),
1692–1702.
http://dx.doi.org/10.1016/j.jenvman.2008.12.001, PMid:19110363
Bester, P. & Penzhorn, B., 2002, ‘Disease prevention and management on game ranches’, in B.L. Penzhorn (ed.), Proceedings of a
Symposium on Game Ranch Planning and Management, pp. 23–30, Onderstepoort, Pretoria. Blaha, T., 1999, ‘Epidemiology and quality assurance application to food safety’, Preventive Veterinary Medicine 39(2), 81–92.
http://dx.doi.org/10.1016/S0167-5877(98)00150-0 Boomker, J., Horak, I.G. & De Vos, V., 1989, ‘Parasites of South African wildlife. IV. Helminths of kudu, Tragelaphus strepsiceros, in the Kruger
National Park’, Onderstepoort Journal of Veterinary Research 56(2), 111–121. PMid:2748130
Capó, V. & Despommier, D.D., 1996, ‘Clinical aspects of infection with Trichinella spp.’, Clinical Microbiology Reviews 9(1),
47. PMid:8665476
Center for Food Security and Public Health (CFSPH), 2005a, Botulism, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2005b, Toxoplasmosis, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2007a, Anthrax, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2007b, Rift Valley fever, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May
2011, from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2009a, Brucellosis, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2009b, Echinococcus, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2009c, Rabies, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Center for Food Security and Public Health (CFSPH), 2009d, Bovine tuberculosis, College of Veterinary Medicine, Iowa State University, Iowa, viewed 19 May 2011,
from
http://www.cfsph.iastate.edu
Chan, J., Baxter, C. & Wenman, W.M., 1989, ‘Brucellosis in an Inuit child, probably related to caribou meat consumption’,
Scandinavian Journal of Infectious Diseases 21(3),
337–338.
http://dx.doi.org/10.3109/00365548909035706, PMid:2569231
Chomel, B.B., Belotto, A. & Meslin, F.X., 2007, ‘Wildlife, exotic pets, and emerging zoonoses’, Emerging Infectious Diseases 13(1),
6.
http://dx.doi.org/10.3201/eid1301.060480, PMid:17370509
Christensen, S.D., 1996, ‘An overview of the food safety situation for the human population in African developing countries: A veterinary
public health approach’, in R. Lindberg (ed.), Veterinary medicine – Impacts on human health and nutrition in Africa,
Proceedings of an international conference, International Livestock Research Institute (ILRI), Addis Ababa, Ethiopia, SLU/Repro, Uppsala, August
27–31, 1995, pp. 157–163. Conradie, I., 2008, ‘The prevalence of helminths in warthogs, bushpigs and some antelope species in Limpopo province, South Africa’,
MSc degree in Veterinary Tropical Disease, Faculty of Veterinary Science, University of Pretoria, Pretoria. Cleaveland, S., Laurenson, M.K. & Taylor, L.H., 2001, ‘Diseases of humans and their domestic mammals: Pathogen characteristics, host range and
the risk of emergency’, Philosophical Transactions of the Royal Society of London B Biological Sciences
356(1411), 991–999.
http://dx.doi.org/10.1098/rstb.2001.0889, PMid:11516377
Cook, R.A., 2005, ‘Emerging diseases at the interface of people, domestic animals and wildlife: The role of wildlife in our understanding of highly
pathogenic avian influenza’, Yale Journal of Biology and Medicine 78(5), 343.PMid:17132341
Cosivi, O., Meslin, F., Daborn, C. & Grange, J., 1995, ‘Epidemiology of Mycobacterium bovis infection in animals and humans, with particular
reference to Africa’, Revue scientifique et technique – Office International des Épizooties 14(3), 733.PMid:8593405
Cosivi, O., Grange, J.M., Daborn, C., Raviglione, M.C., Fujikura, T., Cousins, D. et al., 1998, ‘Zoonotic tuberculosis due to Mycobacterium bovis
in developing countries’, Emerging Infectious Diseases 4(1),
59.
http://dx.doi.org/10.3201/eid0401.980108, PMid:9452399
Daszak, P., Cunningham, A.A. & Hyatt, A.D., 2000, ‘Emerging infectious diseases of wildlife –Threats to biodiversity and human health’, Science 287(5452),
443–449.
http://dx.doi.org/10.1126/science.287.5452.443, PMid:10642539
De la Rua-Domenech, R., 2006, ‘Human Mycobacterium bovis infection in the United Kingdom: Incidence, risks, control measures and review of the zoonotic aspects of bovine tuberculosis’,
Tuberculosis, 86(2), 77–109.
http://dx.doi.org/10.1016/j.tube.2005.05.002, PMid:16257579
Food and Agricultural Organization (FAO), 2010, Bushmeat consumption, wildlife trade and global public health risks, Agricultural Department, Animal
Production and Health Division, viewed 17 May 2011, from
http://www.fao.org Food and Agricultural Organization (FAO), 2011, No more deaths from rinderpest, Agricultural Department, Animal Production and Health Division,
viewed 21 June 2011, from
http://www.fao.org Food and Agricultural Organization (FAO), 2012, International Portal on Food Safety, Animal and Plant Health (IPFSAPH), viewed 21 June 2011,
from
http://www.ipfsaph.org Gauteng Department of Agriculture and Rural Development (GDARD), 2012, ‘GDARD Bulletin, 2/1/2012’, viewed 15 June 2011,
from
http://www.gdard.gpg.gov.za Gauthier-Clerc, M., Lebarbenchon, C. & Thomas, F., 2007, ‘Recent expansion of highly pathogenic avian influenza H5N1: A critical review’, Ibis
149, 202–214.
http://dx.doi.org/10.1111/j.1474-919X.2007.00699.x
Geering, W.A., Roeder, P.L. & Obi, T.U., 1999, ‘Manual on the preparation
of national animal disease emergency preparedness plans’, Food and Agriculture Organization (FAO) of the United Nations, Rome, viewed 16 September 2012,
from
http://www.fao.org
GlobalGAP, 2007, ‘Integrated farm assurance standard’, Germany, viewed 15 May 2011, from http://www.global gap.org Godfroid, J., 2002, ‘Brucellosis in wildlife’, Revue scientifique et technique – Office International des Épizooties 21(2), 277–286. Gortázar, C., Ferroglio, E., Höfle, U., Frölich, K. & Vicente, J., 2007, ‘Diseases shared between wildlife and livestock: A European
perspective’, European Journal of Wildlife Research 53, 241–256.
http://dx.doi.org/10.1007/s10344-007-0098-y Gregory, N.G., 2000, ‘Consumer concerns about food’, Outlook on Agriculture 29(4),
251–257.
http://dx.doi.org/10.5367/000000000101293310 Hahn, T., Olsson, P., Folke, C. & Johansson, K., 2006, ‘Trust-building, knowledge generation and organizational innovations: The role of a
bridging organization for adaptive co-management of a wetland landscape around Kristianstad, Sweden’, Human Ecology 34(4),
573–592.
http://dx.doi.org/10.1007/s10745-006-9035-z Harrison, L.H., Ezzell, J.W., Abshire, T.G., Kidd, S. & Kaufmann, A.F., 1989, ‘Evaluation of serologic tests for diagnosis of
anthrax after an outbreak of cutaneous anthrax in Paraguay’, Journal of
Infectious Diseases 160(4), 706–710.
http://dx.doi.org/10.1093/infdis/160.4.706, PMid:2507648
Herenda, D.C. & Chalmers, P., 1994, ‘Manual on meat inspection for developing countries’, Food & Agriculture
Organization, viewed 20 May 2008, from
http://www.fao.org/ docrep/003/t0756e/T0756E00.htm
Hlokwe, T.M., Jenkins, A.O., Streicher, E.M., Venter, E.H., Cooper, D., Godfroid, J. et al., 2011, ‘Molecular characterisation of
Mycobacterium bovis isolated from African buffaloes (Syncerus caffer) in Hluhluwe-iMfolozi Park in KwaZulu-Natal, South Africa’,
Onderstepoort Journal of Veterinary Research 78(1), 6.
http://dx.doi.org/10.4102/ojvr.v78i1.232 Hoffman, L.C., Muller, M., Schutte, de W., Calitz, F.J. & Crafford, K., 2005, ‘Consumer expectations, perceptions and purchasing of South
African game meat’, South African Journal of Wildlife Research 35(1), 33–42. Hofmeyr, M., Bingham, J., Lane, E., Ide, A. & Nel, L., 2000, ‘Rabies in African wild dogs (Lycaon pitus) in the Madikwe Game Reserve,
South Africa’, Veterinary Record 146(2), 50.
http://dx.doi.org/10.1136/vr.146.2.50, PMid:10678814
Keet, D.F., Kriek, N.P.J., Penrith, M.L., Michel, A. & Huchzermeyer, H., 1996, ‘Tuberculosis in buffaloes (Syncerus caffer) in the Kruger
National Park: Spread of the disease to other species’, Onderstepoort Journal of Veterinary Research 63, 239–244.
PMid:8917861
Keet, D., Kriek, N., Bengis, R. & Michel, A., 2001, ‘Tuberculosis in kudus (Tragelaphus strepsiceros) in the Kruger National Park’,
Onderstepoort Journal of Veterinary Research 68(3), 225. PMid:11769355
Krecek, R.C., Boomker, J., Penzhorn, B.L. & Scheepers, L., 1990, ‘Internal parasites of giraffes (Giraffa camelopardalis
angolensis) from Etosha National Park, Namibia’, Journal of Wildlife Diseases 26(3), 395–397.
PMid:2388363
Li, H., Shen, D.T., Jessup, D.A., Knowles, D.P., Gorham, J.R., Thorne, T. et al., 1996, ‘Prevalence of antibody to malignant
catarrhal fever virus in wild and domestic ruminants by competitive-inhibition ELISA’, Journal of Wildlife Diseases 32(3), 437–443.
PMid:8827669
Liddell, S. & Bailey, D., 2001, ‘Market opportunities and threats to the US pork industry posed by traceability systems’,
International Food and Agribusiness Management 4, 287–302.
http://dx.doi.org/10.1016/S1096-7508(01)00081-7 Madsen, M. & Anderson, E.C., 1995, ‘Serologic survey of Zimbabwean wildlife for brucellosis’, Journal of Zoo and
Wildlife Medicine 26(2), 240–245. Michel, A.L., 2002, ‘Implications of tuberculosis in African wildlife and livestock’, Annals of the New York Academy of
Sciences 969, 251–255.
http://dx.doi.org/10.1111/j.1749-6632.2002.tb04387.x, PMid:12381600
Michel, A.L., Bengis, R.G., Keet, D., Hofmeyr, M., Klerk, L.M.D., Cross, P.C. et al., 2006, ‘Wildlife tuberculosis in South
African conservation areas: Implications and challenges’, Veterinary Microbiology 112(2-4), 91–100.
http://dx.doi.org/10.1016/j.vetmic.2005.11.035, PMid:16343819
Michel, A., Coetzee, M., Keet, D., Maré, L., Warren, R., Cooper, D. et al., 2009, ‘Molecular epidemiology of
Mycobacterium bovis isolates from free-ranging wildlife in South African game reserves’, Veterinary Microbiology 133(4),
335–343.
http://dx.doi.org/10.1016/j.vetmic.2008.07.023, PMid:18786785
Montali, R.J., Mikota, S. & Cheng, L., 2001, ‘Mycobacterium tuberculosis in zoo and wildlife species’,
Revue scientifique et technique – Office International des Épizooties 20(1), 291.
PMid:11288517
Mwenye, K., Sizia, S. & Peterson, D., 1996, ‘Factors associated with human anthrax outbreak in the Chikupo and
Ngandu villages of Murewa district in Mashonaland East province, Zimbabwe’, The Central African Journal of Medicine 42(11), 312.
PMid:9130412
Oberem, P. & Oberem, P., 2011, A guide to animal diseases in South Africa: Game, Briza, Pretoria. Ogden, N.H. & Tsao, J.I., 2009, ‘Biodiversity and Lyme disease: Dilution or amplification?’, Epidemics
1(3), 196–206.
http://dx.doi.org/10.1016/j.epidem.2009.06.002, PMid:21352766
Oh, P., Granich, R., Scott, J., Sun, B., Joseph, M., Stringfield, C. et al., 2002, ‘Human exposure following
Mycobacterium tuberculosis infection of multiple animal species in a metropolitan zoo’, Emerging Infectious Diseases 8(11), 1290.
http://dx.doi.org/10.3201/eid0811.020302, PMid:12453358
Parra, A., García, A., Inglis, N., Tato, A., Alonso, J., Hermoso De Mendoza, M. et al., 2006, ‘An epidemiological
evaluation of Mycobacterium bovis infections in wild game animals of the Spanish Mediterranean ecosystem’, Research
in Veterinary Science 80(2), 140–146. Paskin, R., 1999, Manual on livestock disease surveillance and information systems, FAO, Rome, viewed 09
May 2011, from
http://www.fao.org Paulsen, P. & Smulders, F.J.M., 2004, ‘Infectious diseases of meat animals’,
in W.K. Jensen, C. Devine & M. Dikeman (eds.), Encyclopaedia of Meat Sciences, pp. 649–656,
Elsevier Academic Press, London.
http://dx.doi.org/10.1016/B0-12-464970-X/00024-6 Pavlin, B.I., Schloegel, L.M. & Daszak, P., 2009, ‘Risk of importing zoonotic diseases
through wildlife trade, United States’, Emerging Infectious Diseases 15(11), 1721. PMid:19891857
Phillips, C.J.C., Foster, C.R.W., Morris, P.A. & Teverson, R., 2003, ‘The transmission of
Mycobacterium bovis infection to cattle’, Research in Veterinary Science 74(1), 1–15.
http://dx.doi.org/10.1016/S0034-5288(02)00145-5
Pozio, E., 2005, ‘The broad spectrum of Trichinella hosts: From cold-to warm-blooded animals’,
Veterinary Parasitology 132(1-2), 3–11.
http://dx.doi.org/10.1016/j.vetpar.2005.05.024, PMid:15970384
Pozio, E., Capelli, O., Marchesi, L., Valeri, P. & Rossi, P., 1988, ‘Third outbreak of trichinellosis
caused by consumption of horse meat in Italy’, Annales de parasitologie humaine et comparée 63(1), 48.
PMid:3041893
Radder, L. & Le Roux, R., 2005, ‘Factors affecting food choice in relation to venison: A South African
example’, Meat Science 71(3), 583–589.
http://dx.doi.org/10.1016/j.meatsci.2005.05.003, PMid:22060937
Red Meat and Research Development South Africa (RMRDSA), 2010, ASF in soft tampans, Research project, viewed
01 February 2012, from
http://www.rmrdsa.co.za Rupprecht, C.E. & Fekadu, M., 1995, ‘The ascension of wildlife rabies: A cause for public health concern or
intervention?’, Emerging Infectious Diseases 1(4), 107–114.
http://dx.doi.org/10.3201/eid0104.950401, PMid:8903179
Scoones, I., Bishi, A., Mapitse, N., Moerane, R., Penrith, M-L.P., Sibanda, R. et al., 2010, ’Foot-and-mouth disease and
market access: Challenges for the beef industry in southern Africa’, Pastoralism 1(2), 135–164. Shanthikumar, S.R. & Atilola, M.A., 1990, ‘Outbreaks of rinderpest in wild and domestic animals in Nigeria’,
Veterinary Record 126, 306–307. PMid:2343518
Shitaye, J.E., Tsegaye, W. & Pavlik, I., 2007, ‘Bovine tuberculosis infection in animal and human populations in Ethiopia:
A review’, Veterinarni Medicina 52(8), 317–332. Skinner, J., 1970, ‘Game-ranching in Africa as a source of meat for local consumption and export’, Tropical Animal Health
and Production 2(3), 151–157.
http://dx.doi.org/10.1007/BF02359682
Sleeman, J., 2006, ‘Wildlife zoonoses for the veterinary practitioner’, Journal of Exotic Pet Medicine, 15(1), 25–32.
http://dx.doi.org/10.1053/j.jepm.2005.11.006 South African Government, 1984, ‘Animal Diseases Act, No. 35 of 1984’, viewed 09 May 2011, from
http://www.daff.gov.za Swanepoel, R., Barnard, B., Meredith, C., Bishop, G., Brückner, G., Foggin, C. et al., 1993, ‘Rabies in southern
Africa’, Onderstepoort Journal of Veterinary Research 60(4), 325. Tambi, E., Mania, O.W., Mukhebi, A. & Randolph, T., 1999, ‘Economic impact assessment of rinderpest control in Africa’,
Revue scientifique et technique – Office International des Épizooties 18(2), 458. PMid:10472679
Tarnoczi, T.J. & Berkes, F., 2010, ‘Sources of information for farmers’ adaptation practices in Canada’s prairie
agro-ecosystem’, Climatic Change 98(1), 299–305.
http://dx.doi.org/10.1007/s10584-009-9762-4
Taylor, J.P. & Perdue, J.N., 1989, ‘The changing epidemiology of human brucellosis in Texas, 1977–1986’, American
Journal of Epidemiology 130(1), 160–165. PMid:2787107
Taylor, L.H., Latham, S.M. & Woolhouse, M.E., 2001, ‘Risk factors for human disease emergence’, Philosophical
Transactions of the Royal Society of London B Biological Sciences 356, 983–989.
http://dx.doi.org/10.1098/rstb.2001.0888, PMid:11516376
Thoen, C., Lobue, P. & De Kantor, I., 2006, ‘The importance of Mycobacterium bovis as a zoonosis’, Veterinary
Microbiology 112(2), 339–345.
http://dx.doi.org/10.1016/j.vetmic.2005.11.047, PMid:16387455
Thomson, G. & Penrith, M-L., 2011, ‘Animal health policy, legislation and trade in beef in the five participating states of the Kavango-Zambezi
transfrontier conservation area (KAZA TFCA)’, Technical Report to the Wildlife Conservation Society’s AHEAD Programme. Thornton, P., Van de Steeg, J., Notenbaert, A. & Herrero, M., 2009, ‘The impacts of climate change on livestock and
livestock systems in developing countries: A review of what we know and what we need to know’, Agricultural
Systems 101(3), 113–127.
http://dx.doi.org/10.1016/j.agsy.2009.05.002 Ungerer, W., 2008, Personal interview, Deputy Director: Epidemiology, Directorate Veterinary Services, National Department
of Agriculture, Forestry and Fisheries, Pretoria. Van der Merwe, M., Bekker, J.L., Van der Merwe, P. & Michel, A., 2009, ‘Cooking and drying as effective mechanisms in
limiting the zoonotic effect of Mycobacterium bovis in beef’, Journal of the South African Veterinary Association 80, 142–145.
PMid:20169745 Van Wyk, I.C. & Boomker, J., 2011, ‘Parasites of South African wildlife. XIX. The prevalence of helminths in some common
antelopes, warthogs and a bushpig in the Limpopo province, South Africa’, Onderstepoort Journal of Veterinary Research
78(1).
http://dx.doi.org/10.4102/ojvr.v78i1.308 White, Jr, P., Baker, Jr, E., Roth, A., Williams, W. & Stephens, T., 1974, ’Brucellosis in a Virginia meat-packing plant’,
Archives of Environmental Health 28(5), 263. PMid:4821770
Whitehouse & Associates, 2011, ‘Technical Report: Regulatory Environment for Animal Feeds in Zambia, Malawi, Mozambique,
Zimbabwe, Namibia and Botswana’, AECOM International Development, USAID/Southern Africa, Southern African Trade Hub, Gaborone, Botswana. World Health Organization (WHO), 1994a, ‘Report of WHO working group on zoonotic tuberculosis (Mycobacterium bovis),
with the participation of FAO. June 14’, Geneva, World Health Organization. Unpublished: who/cds/vph/94.137. World Health Organization (WHO), 1994b, ‘Zoonotic tuberculosis (Mycobacterium bovis), Memorandum from a WHO meeting
(with the participation of the Food and Agriculture Organization’, Bulletin of the WHO 72(6), 851–857. World Health Organization (WHO), 2010, ‘Rift Valley fever in South Africa – update, global alert and response (GAR)’,
04 May 2010, viewed 16 September 2012, from
http://www.who.int/csr/don/2010_05_12/en/index.html. World Organisation for Animal Health (OIE), 2005, ‘Report of the meeting of the OIE working group on wildlife diseases,
Paris, 14–16 February 2005’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2006a, ‘Report of the meeting of the OIE working group on wildlife diseases,
Paris, 20–23 February 2006’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2006b, ‘Economic analysis: Prevention versus outbreak costs’, viewed 15 June
2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2007, ‘Report of the meeting of the OIE working group on wildlife diseases, Paris,
12–15 February 2007’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2008a, ‘Report of the meeting of the OIE working group on wildlife diseases, Paris,
28–31 January 2008’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2008b, ‘Report of the meeting of the OIE working group on wildlife diseases, Paris,
26–29 January 2009’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2010a, ‘Report of the meeting of the OIE working group on wildlife diseases,
Paris, 1–4 February 2010’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2010b, ‘Report of the meeting of the OIE working group on wildlife diseases, Paris,
12–10 October 2010’, viewed 15 June 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2011a,’OIE listed diseases’, viewed 07 May 2011, from
http://www.oie.int World Organisation for Animal Health (OIE), 2011b, ‘Terrestrial Animal Health Code’, viewed 07 May 2011, from
http://www.oie.int Zieger, U., Pandey, G., Kriek, N. & Cauldwell, A., 1998, ‘Tuberculosis in Kafue lechwe (Kobus leche kafuensis) and in a
bushbuck (Tragelaphus scriptus) on a game ranch in central province, Zambia’, Journal-South African veterinary association 69, 98–101. Zinsstag, J., Kazwala, R., Cadmus, I. & Ayanwale, L., 2008, ‘Mycobacterium bovis in Africa’, in Mycobacterium bovis
infection in animals and humans, pp. 199–210, Blackwell, Oxford. http://dx.doi.org/10.1002/9780470344538.ch19 |