key: cord-1048280-kalwyvuo
authors: Banu, Tanjina Akhtar; Sarkar, M. Murshed Hasan; Akter, Shahina; Goswami, Barna; Jahan, Iffat; Osman, Eshrar; Uzzaman, Mohammad Samir; Habib, M. Ahashan; Mahmud, Abu Sayeed Mohammad; Uddin, Mohammad Mohi; Nafisa, Tasnim; Molla, M. Maruf Ahmed; Yeasmin, Mahmuda; Akram, Arifa; Khan, M. Salim
title: Genome Sequencing of the SARS-CoV-2 Delta (B.1.617.2) Variant of Concern Detected in Bangladesh
date: 2021-12-02
journal: Microbiol Resour Announc
DOI: 10.1128/mra.00849-21
sha: 80e793992fce9b94eea08f55ecdd3791f433f17c
doc_id: 1048280
cord_uid: kalwyvuo

We report the near-complete genome sequence and phylogenetic analysis of a severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant (B.1.617.2) strain. This variant is associated with increased transmission and immune evasion.

and C1247F) (Fig. 1B) . L452R, T478K, and P681R are three key mutations in the spike protein; it has been suggested that they are responsible for making the strain more transmissible and infectious (8) .

It has been confirmed that this patient did not report any recent travel history or known contact with recent travelers, so it is possible that this infection resulted from local community transmission of the SARS-CoV-2 Delta variant (B.1.617.2) in Bangladesh in May 2021.

Data availability. The sequence has been deposited at GenBank under accession number MZ437368. The raw sequence reads have been deposited at the NCBI Sequence Read Archive (SRA) under BioProject accession number PRJNA741723 and SRA accession number SRP336330.

WHO. 2021. Weekly epidemiological update on COVID-19-27

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We extend particular thanks to Architect Yeafesh Osman, honorable minister of science and technology, Government of the People's Republic of Bangladesh. We are grateful to M. Aftab Ali Shaikh, chairman of BCSIR, for his continuous support of the team.We thank the NILMRC for providing us with the samples and many other supports.