key: cord-1044740-vjfs701d
authors: Gambichler, T.; Reuther, J.; Stücker, M.; Stranzenbach, R.; Torres‐Reyes, C.; Schlottmann, R.; Schmidt, W.E.; Hayajneh, R.; Sriram, A.; Becker, J.C.
title: SARS‐CoV‐2 spike protein is present in both endothelial and eccrine cells of a chilblain‐like skin lesion
date: 2020-10-01
journal: J Eur Acad Dermatol Venereol
DOI: 10.1111/jdv.16970
sha: 7767d3c2e761dc57e422ce67a34c7c1f5144b266
doc_id: 1044740
cord_uid: vjfs701d

Data on SARS‐CoV‐2 detection in lesional skin is controversial.(1‐8) We report a PCR‐proven COVID‐19 patient with a chilblain‐like SARS‐CoV‐2 positive skin lesion. An 80‐year‐old woman presented to the emergency department at the End of March 2020. She reported an onset of fever (38.4 C°) several days before admission, along with cough and shortness of breath. RT‐PCR from a nasopharyngeal swab was positive for SARS‐CoV‐2. An X‐ray showed evidence for right‐sided pneumonic infiltrates.

Data on SARS-CoV-2 detection in lesional skin is controversial. [1] [2] [3] [4] [5] [6] [7] [8] We report a PCR-proven COVID-19 patient with a chilblain-like SARS-CoV-2 positive skin lesion. An 80-year-old woman presented to the emergency department at the End of March 2020. She reported an onset of fever (38.4 C°) several days before admission, along with cough and shortness of breath. RT-PCR from a nasopharyngeal swab was positive for SARS-CoV-2. An X-ray showed evidence for right-sided pneumonic infiltrates. A blood collection revealed increased leukocyte count, Creactive protein, ferritin, and decreased sodium. She was treated with nasal oxygen, intravenous sodium chloride infusions, and transient hydrocortisone to substitute possible hypocortisolism. 

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