key: cord-1041327-ic2h01gm authors: Wang, Xinghuan; Pan, Zhenyu; Cheng, Zhenshun title: Association between 2019-nCoV transmission and N95 respirator use date: 2020-02-19 journal: nan DOI: 10.1101/2020.02.18.20021881 sha: 6186828135d9e5e7e50f66567505d02e910b3ee2 doc_id: 1041327 cord_uid: ic2h01gm 2019-nCoV had caused pneumonia outbreak in Wuhan. Existing evidence have confirmed the human-to-human transmission of 2019-nCoV. We retrospectively collected infection data from 2 January to 22 January at six departments from Zhongnan Hospital of Wuhan University. In our study, we found N95 respirators, disinfection and hand washing can help to reduce the risk of 2019-nCoV infection in medical staffs. Our results call for re-emphasizing strict occupational protection code in battling this novel contagious disease. The risk of 2019-nCoV infection was higher in the open area than in the quarantined area. N95 may be more effective for 2019-nCoV infections. All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.18.20021881 doi: medRxiv preprint Cases of a novel type of contagious pneumonia were first discovered a month ago in Wuhan. The Centers for Disease Control and Prevention (CDC) and Chinese health authorities have determined and announced that a novel coronavirus (CoV), denoted as 2019-nCoV, had caused this pneumonia outbreak. 1,2 Existing evidence have confirmed the human-to-human transmission of 2019-nCoV. 3 We retrospectively collected infection data from 2 January to 22 January at six departments (Respiratory, ICU, Infectious Disease, Hepatobiliary Pancreatic Surgery, Trauma and Microsurgery, and Urology) from Zhongnan Hospital of Wuhan University. Medical staffs in these department follow differential routines of occupational protection: the medical staff in departments of Respiratory, ICU, and Infectious Disease wore N95 respirators, disinfected and clean hands frequently (N95 group); due to people were not enough for the knowledge of the 2019-nCoV in these early days of the pneumonia outbreak, the medical staff in the other three departments wore no medical masks, disinfected and clean hands occasionally (no-mask group). author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The copyright holder for this preprint (which was not peer-reviewed) is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.02.18.20021881 doi: medRxiv preprint All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The copyright holder for this preprint (which was not peer-reviewed) is the The continuing 2019-nCoV epidemic threat of novel coronaviruses to global health -The latest 2019 novel coronavirus outbreak in Wuhan, China Evolution of the novel coronavirus from the ongoing Wuhan outbreak and modeling of its spike protein for risk of human transmission. Sci China Life Sci N95 Respirators vs Medical Masks for Preventing Influenza Among Health Care Personnel: A Randomized Clinical Trial All rights reserved. No reuse allowed without permission author/funder, who has granted medRxiv a license to display the preprint in perpetuity. The copyright holder for this preprint (which was not peer-reviewed) is the