key: cord-1040799-5syp9oum
authors: Speeckaert, Marijn M.; Speeckeart, Reinhart; Delanghe, Joris R.
title: Genetic polymorphisms, vitamin D binding protein and vitamin D deficiency in COVID-19
date: 2021-02-04
journal: Eur Respir J
DOI: 10.1183/13993003.04638-2020
sha: 96f3ee3b425ec5c2a19bc5e39c8515d96bd69b06
doc_id: 1040799
cord_uid: 5syp9oum

Besides adiposity and skin pigmentation, different DBP polymorphisms could also partly influence the low 25(OH)D concentrations in the BAME group with COVID-19.

To the editor, With interest, we read the paper of Faniyi et al. [1] , which investigated the relationship between vitamin D status and seroconversion for COVID-19 in UK healthcare workers. More specifically, vitamin D deficiency was an independent risk factor for the development of COVID-19 seroconversion, with the biggest differences seen in the Black Asian and minority ethnic (BAME) male group. Although several co-morbidities were taken into account, we would In conclusion, besides adiposity and skin pigmentation, which were taken into account in the paper of Faniyi et al.

[1], different loci (e.g. the DBP gene) could also partly influence the low 25(OH)D concentrations in the BAME group with COVID-19.

All authors contributed to the writing, review and approval of the final copy of the manuscript.

All other authors declare no competing interests. 

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