key: cord-1036887-8e44sxb5
authors: Shome, Debraj; Doshi, Komal; Vadera, Sapna; Kapoor, Rinky
title: Delayed hypersensitivity reaction to hyaluronic acid dermal filler post‐COVID‐19 viral infection
date: 2021-03-15
journal: J Cosmet Dermatol
DOI: 10.1111/jocd.14046
sha: 9ca067a613bb770e87126c4eb2b4cb0c4f15cde4
doc_id: 1036887
cord_uid: 8e44sxb5

Dermal fillers have been an effective therapy for people pursuing non-invasive facial rejuvenation.1 Hyaluronic acid (HA) soft tissue fillers specifically; have become a popular device for enhancement of facial features over the last few years.2 We are presenting a case of a 32 years old lady treated at The Esthetic Clinics, Mumbai in February 2020 for facial rejuvenation. She was rejuvenated using dermal fillers at multiple sites on her face. The patient is a regular patient with us and had facial rejuvenation with dermal fillers regularly since the past 6 years and has never reported any reactions or adverse effects related to dermal fillers in the past. (Figure 1-A & B).

To the Editor, Dermal fillers have been an effective therapy for people pursuing noninvasive facial rejuvenation. 1 Hyaluronic acid (HA) soft tissue fillers specifically have become a popular device for an enhancement of facial features over the last few years. 2 We are presenting a case of a 32-year-old woman treated at The Esthetic Clinics, Mumbai, in February 2020 for facial rejuvenation.

She was rejuvenated using dermal fillers at multiple sites on her face.

The patient is a regular patient with us and had facial rejuvenation with dermal fillers regularly for the past 6 years and has never reported any reactions or adverse effects related to dermal fillers in the past ( Figure 1A Hyaluronic acid molecules in all dermal fillers are the same polysaccharide molecules that make up a large portion of our skin. As a result, the HA molecule itself is not generally known to be an immunogen. 4 In previous articles, it was noted that the swelling and hypersensitive reaction in the HA filler injection site were encoun- 

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