key: cord-1030927-kped3e2i
authors: Clark, Sarah A.; Teman, Nicholas R.
title: Commentary: Cardiac surgery in COVID patients: Figuring it out as we go
date: 2021-04-27
journal: J Thorac Cardiovasc Surg
DOI: 10.1016/j.jtcvs.2021.04.058
sha: 092384df6978bad1550f5a86dc3fe419922f77e7
doc_id: 1030927
cord_uid: kped3e2i

nan

Commentary: Cardiac surgery in COVID patients: Figuring it out as we go Sarah A. Clark, MD, and Nicholas R. Teman, MD Since the outbreak of the novel SARS-CoV-2 (COVID-19) viral pandemic in late 2019, the entire world has had to make decisions, ranging from how to treat the profound respiratory complications of COVID-19 pneumonia to how to maintain a globalized economy with significant travel and trade restrictions, based on very limited information. Despite our limited knowledge of this disease, many of those decisions have had an enormous impact on our dayto-day lives, forcing everyone to grapple with uncertainty and changing norms. Although our knowledge of this virus and how to manage it has grown exponentially over the last year, this brief communication by the Cardio-Thoracic Interdisciplinary Research Network and COVIDSurg Collaboration serves as a reminder of how little we know about COVID-19 and its sequelae. 1 In this multicenter international observational cohort study, unadjusted outcomes of patients undergoing cardiac surgery with known COVID-19 infection within the perioperative period (7 days preoperatively up to 30 days postoperatively) were examined. Patients who contracted COVID-19 in the perioperative period exhibited higher than normal rates of respiratory complications, including prolonged mechanical ventilation and pneumonia. 2 The authors also report a 20.8% mortality among patients who were diagnosed with COVID-19 within 30 days of surgery. These findings underscore the incredible clinical impact that COVID-19 infection can have, even among patients undergoing "minor" procedures. These data should give all cardiac surgeons pause, and highlight the importance of vigilance to prevent perioperative COVID-19 infection.

This study has some limitations, which are a reflection of its accelerated nature and a desire for timely results in the face of an oft-changing pandemic. The series includes only patients operated on before July 2020, relatively early in the pandemic, when our methods of diagnosing, treating, and preventing this disease were very much in their infancy. Furthermore, the study lacked a comparison group and risk stratification of the study population. Unfortunately, with this study design, it is unclear whether the patients who contracted COVID-19 were at higher risk for any pulmonary complication. Without a comparison group or risk stratification of the patients, it is also difficult to accurately interpret the high mortality rate, given that 64.7% of these operations were performed emergently, 70.0% of the patients were men, and 62.3% of the patients were over age 60, all of which are established risk factors for mortality. [3] [4] [5] The authors did, however, attempt to mitigate some of these confounders by including a subgroup analysis in which they compared characteristics between survivors and nonsurvivors.

Despite its limitations in data and design, this study is a step toward a better understanding of COVID-19 and represents the start of this growing body of literature. The authors attempted to draw logical conclusions from their limited data and use that to make recommendations for improved patient care during this pandemic. We can use studies such as these as stepping stones and keep figuring things

Early outcomes and complications following cardiac surgery in COVID-19 positive patients: an international cohort study

Risk factors for postoperative pneumonia after cardiac surgery and development of a preoperative risk score

Acute treatment of ST-segment elevation myocardial infarction: is there a role for the cardiac surgeon?

The influence of gender on the outcome of coronary artery bypass surgery

Coronary artery bypass graft surgery in the elderly: indications and outcome

out as we go, just as everyone has had to do navigate this post-COVID world.