key: cord-1030443-r0o2p8mz authors: Chin, Kazuo title: Might CPAP prevent exacerbation in patients with COVID-19 with or without obstructive sleep apnea? date: 2021-01-02 journal: Sleep Biol Rhythms DOI: 10.1007/s41105-020-00300-x sha: aedfd181bbbaaf2fa88e68f3878c7a1f6f133f1f doc_id: 1030443 cord_uid: r0o2p8mz nan 19 is scant. The reported data on the prevalence of OSA in COVID-19 patients showed lower rates than in the general population. Richardson As to this issue [6] , Sullivan, who was the inventor of nasal continuous positive airway pressure treatment (CPAP), stated that CPAP should be used not only in the management of patients with OSA but in managing COVID-19 patients with or without hypoxemia [7] , although some recommended not to use CPAP. He proposed the hypothesis that unrecognized snoring and sleep apnea might be significant mechanisms increasing viral aspiration during sleep and that this may induce aspiration of COVID-19 virus, worsening pulmonary lesions, and inducing viral pneumonia, which might be prevented by CPAP [7] . Although this hypothesis is not fully proven, the use of well-fitted CPAP masks with appropriate circuit filters can minimize viral spread to others, including medical staff, and may lead to good management and improved prognosis for patients with COVID-19. We also should recognize that at present it has not been proven that such CPAP systems even if used in a negative pressure room are completely safe for medical staff. Considering these issues, it would be better for us to use a proper CPAP system under appropriate circumstances for COVID-19 patients cautiously because the benefit of using CPAP for the management of COVID-19 patients would be superior to not using it with regard to patients' prognosis, as Sullivan proposed [7] . A novel coronavirus from patients with pneumonia in China Mild or moderate Covid-19 Estimation of the global prevalence and burden of obstructive sleep apnoea: a literature-based analysis Impact of sleep characteristics and obesity on diabetes and hypertension across genders and menopausal status: the Nagahama study Presenting characteristics, comorbidities, and outcomes among 5700 patients hospitalized with COVID-19 in the Sleep apnea and COVID-19 mortality and hospitalization Snoring and obstructive sleep apnoea as risk factors in SARS-Cov-2: can nasal CPAP during sleep reduce pneumonia risk?