key: cord-1029199-u1y0v7pj authors: Ghazawy, Eman R; Ewis, Ashraf A; Mahfouz, Eman M; Khalil, Doaa M; Arafa, Ahmed; Mohammed, Zeinab; Mohammed, El-Nabgha F; Hassan, Ebtesam E; Abdel Hamid, Sarah; Ewis, Somaya A; Mohammed, Abd El-Nassir S title: Psychological impacts of COVID-19 pandemic on the university students in Egypt date: 2020-12-25 journal: Health Promot Int DOI: 10.1093/heapro/daaa147 sha: 50bd532059e106a668565ed978f6d13b34b9e83a doc_id: 1029199 cord_uid: u1y0v7pj University students are at elevated risk for mental health problems. The COVID-19 pandemic and subsequent public health measures taken to combat it burdened the students’ life with additional dramatic psychological impacts. The aim of this study was to investigate the psychological impacts that affected the university students in Egypt during the COVID-19 pandemic. An online survey was sent to the Egyptian university students via all means of online communication during the first week of May 2020 by using a non-probability snowball sampling. A survey included a short version Depression Anxiety Stress Scale-21 (DASS-21) and socio-demographic data. Overall, 70.5, 53.6 and 47.8% of Egyptian students had depression, anxiety and stress, respectively. Being a female, having a relative or acquaintance infected with COVID-19, having a preexisting chronic disease and lacking of psychological support from families, community and universities increase the risk of depression, anxiety and stress among Egyptian students. Being a medical student is associated with depression while, spending more time to follow news of COVID-19 pandemic is associated with increased anxiety. Egyptian students experience varying levels of psychological disturbance during COVID-19 pandemic. This study suggests that mental health of the university students should be carefully, monitored during the crisis and the universities should provide psychological-oriented services, adapted to these circumstances to mitigate its emotional impact on the students. On 11 March 2020, the World Health Organization (WHO) declared, the novel Corona Virus Disease (COVID-19) as a pandemic after it has spread in more than 110 countries by then. This COVID-19 pandemic continued its course, crossing the borders to all the continents invading most of the globe and it affected almost all countries and territories very far away from its starting origin in Wuhan, China, on December 2019 (WHO, 2020; . Essentially, COVID-19 is an infectious viral disease that is transmitted from human-to-human through droplets whether direct; during coughing, sneezing of a patient or a carrier of the disease or indirect; through getting in contact with the patient's droplets on close contact, shaking hands, using his personal articles or touching surfaces soaked with his droplets containing the virus. The COVID-19 virus finds its way into the human body through the mucus membranes of the mouth, nose and eyes (UNICEF, 2020; . Clinical picture of COVID-19 infected patients varies significantly, from being asymptomatic to having severe form of the disease. In most cases, high fever, cough, chest tightness, chills, sore throat, general weakness, fatigue, muscular pain, diarrhea, impaired taste and smelling sensations could occur. In the severe cases, pneumonia, acute respiratory distress syndrome, microcoagulopathies, sepsis and septic shock may occur, and in many instances it could lead to death. Reports show that clinical deterioration can occur rapidly, often during the second week of the course of the disease (Huang et al., 2020) . Additionally, patients with underlying medical problems such as cardiovascular disease, diabetes, chronic respiratory disease, cancer and old-age people are more likely to experience serious illness . As on the morning of 12 June 2020, a total of 7 628 356 confirmed cases of COVID-19 infections and its death tool points toward 408 645 deaths. Scenario is changing every day with increase in number of infection and death (Corona Virus Resource Centre, 2020) . The COVID-19 pandemic enforced many international governments to take rigorous decisions to control the infections or at least to lower its speedy transmission. Many countries declared nationwide lock-down, banned the local and international flights, suspended attendance to schools, universities and business operations, declined all kinds of gatherings and asked the people to stay at home. Additionally, the media coverage has been focusing on the hot issue of COVID-19 in an hourly manner, by announcing the numbers of newly confirmed infections and the new reported deaths in every country. As a result the people were affected by such world panic actions and presented a wide range of psychological disturbances Yang et al., 2020; . On 14 February, Egypt announced its first COVID-19 case. Thereafter, Egypt scaled up preventive measures, with a partial lockdown starting on 25 March. As of 31 March, Egypt announced 710 COVID-19 cases and 46 related deaths. By the beginning of April of 2020, there were over 800 confirmed cases, with more than 50 fatalities, and a rapid tendency toward increase. This might be an underestimate, as the facilities of 2019NCV test are very limited (Hassany et al., 2020) . University students are the most active and widely moving age group. Suddenly, with COVID-19 pandemic they were directly affected by banning their attendance to the universities, staying at home, not meeting friends, not exercising, no traveling, as well as the fear of getting infected or infecting any of their family members or friends. This extraordinary stressful new life and the required precautions before going out or returning home or even going shopping added burdens to the students. These were not their only stressors, but they had to attend online classes instead of attending their university classrooms, missing the face-to-face learning and the clinical/practical or training lessons. To investigate these psychological impacts that affected the university students in Egypt, we performed this study. All the university students in Egypt were invited to participate in this cross-sectional survey during the first week of May 2020. Because of the lockdown in most countries and in Egypt as well, a non-probability snowball sampling technique was used. A Google survey was created and the link to the survey was sent to the participants by e-mails and via the available social media channels. Starting from the recorded contact details of the university students in the Public Health Departments, Faculty of Medicine of Minia, Beni-Suef, Sohag and Cairo Universities in Egypt. We designed an Arabic questionnaire composed of four sections to collect the data. Section 'Background' included a detailed explanation of the steps, aims and eligibility criteria of the study. Section 'Methods' included questions about the sociodemographic data of the students including age, sex, university, faculty, grade and city where he/she lives. Section 'Results' included questions about the previous month only and includes the following: average daily sleeping hours (<6, 6À8 or >8 h/day), watching or reading news about COVID-19 (<1, 2À4 or >4 h/day), getting enough emotional support from family, society and university. Section 'Discussion' included the Arabic version of the Depression Anxiety Stress Scale-21 (DASS-21). The DASS-21 is a quantitative measure of depression, anxiety and stress symptomatology (seven statements each) during the past week. The depression statements evaluate hopelessness, dysphoria, self-deprecation, devaluation of life, lack of interest and involvement, anhedonia and inertia. The anxiety statements evaluate skeletal muscle effects, autonomic arousal, situational anxiety and subjective experience of anxious affect. The stress scale evaluates nervous arousal, difficulties in relaxation and being easily upset or over-reactive. Every participating student should decide how much the statements apply for him/her using a scale from 0 to 3 where 0 refers to 'did not apply to me at all', 1 refers to 'applied to me to some degree or some of the time', 2 refers to 'applied to me to a considerable degree or a good part of the time' and 3 refers to 'applied to me very much or most of the time'. The score of each axis is multiplied by 2 to lie within a 0À42 scale where higher scores indicate worse outcomes (Lovibond and Lovibond, 1995; Ali et al., 2017) . The subscales are scored as follows: for depression; normal (0À9), mild (10À13), moderate (14À20) and severe to extremely severe (!21), for anxiety; normal (0À7), mild (8À9), moderate (10À14) and severe to extremely severe (!15), and for stress; normal (0À14), mild (15À18), moderate (19À25) and severe to extremely severe (!26) (Lovibond and Lovibond, 1995) . The study protocol was in accordance with the Helsinki declaration and was approved by the research ethical committee of Minia University. The conditions and eligibility criteria of the study was described in the 'Background' section of the questionnaire and students had to agree to proceed to fill in the questions of the rest of the sections and to submit their answers when finishing the questionnaire. They have the full will to determine filling out or declining the survey. Choosing to proceed, filling out and submitting the questionnaire was considered as approval and informed consent of participation. Data were analyzed using the Statistical Package for Social Science (SPSS) released in 2013 (IBM SPSS Statistics for Windows, Version 22.0, IBM Corporation, Armonk, NY, USA). An analysis of descriptive statistics was conducted to illustrate the demographic and other selected characteristics of the respondents; mean 6 standard deviation and frequency distribution for numerical and categorical variables, respectively. Multivariate binary logistic regression was used to identify the significant factors that affect the presence of depression, anxiety and stress among the students. p values <0.05 were considered statistically significant. A total of 1335 Egyptian students from 20 universities participated in the study. The 21À22 year age group constituted 54.8% of the sample. Approximately 61.8% of the students were females and 50.3% resided in urban areas, 52% of the students from medical colleges (Medicine, Pharmacy, Dentistry and Nursing) and 48% were non-medical colleges. The majority of the students (86.5%) were healthy whereas, 13.5% reported some health conditions namely bronchial asthma, diabetes mellitus, hypertension and obesity. About 23.7 and 9.2% of the students had relatives/acquaintances who were infected or died with COVID-19, respectively (Table 1) . Table 2 shows that the psychological health status of college students was affected to varying degrees. Overall, 70.5% of Egyptian students had depression; 24.6, 36.3 and 9.7% were mild, moderate and severe depression, respectively. About 53.6% of students suffered from anxiety of them; 13.6% were mild, 24.7% were moderate and 15.3% were severe to extremely severe. Whereas the proportion of stress among the students was 47.8%, of them; 14% had mild, 19.6% had moderate and 14.2% had severe/extremely severe stress. Based on the score ranges from the DASS manual, the mean scores of depression, anxiety and stress for all students were found at mild level (12.58 6 6.3), (8.36 6 6.6) and (15.17 6 8.3), respectively. This study showed that the majority of Egyptian students (95.5%) were annoyed about the emerging COVID-19. More than half (54.5%) thought that COVID-19 pandemic deserves much concern and 39.9% reported that it is very dangerous and terrifying disease. Only 5.6% of students felt the media coverage of the disease is exaggerated. About one-third (32.6%) of the students claimed that they had enough knowledge about the disease. The most commonly stated sources of knowledge were social media (60.8%) followed by internet websites (20.4%), while a minor proportion of students (2.5%) showed no interest in following COVID-19 pandemic. The majority of students (82.5%) spent <1 h/day to follow regular updates on COVID-19 (Table 3) . The precautionary measures adopted by the Egyptian university students were shown in Table 3 , where 63.3 and 45%, of the students stayed at home and were committed to social distancing. About 31.5% of the students wear masks, gloves and use antiseptics when leaving their houses, however, 61.2% of them did not use antiseptics after returning home. Table 4 shows the multivariable-adjusted ORs (95% CIs) for factors associated with psychological status of Egyptian university students. Being a female had higher odds to have depression, anxiety and stress; the multivariable-adjusted OR (95% CI) were 1.67 (1.28À2.21), 1.71 (1.33À2.19) and 1.81 (1.39À2.33), respectively. Studying at medical colleges was associated with students' depression; OR ¼ 1.46 (1.12À1.59), but not with their stress or anxiety status. Students who had relative or acquaintance infected with COVID-19 were about one and half times more likely to have depression, anxiety and stress than those who did not know affected person. The presence of a chronic health problem was It deserves attention and concern 727 (54.5) It is very dangerous and terrifying 533 ( University students are at elevated risk for mental health problems, and many studies have documented that students report consistently higher levels of mental health problems than the general population (Tomoda et al., 2000; Stallman, 2010; Gaspersz et al., 2012; Denovan and Macaskill, 2017; Tran et al., 2017; Mortier et al., 2018; Williams et al., 2018) . There are numerous complex and inter-related factors that may be contributing to the rise of mental health issues among college students. They experience multiple stressors such as lifestage transitions, academic pressure resulting from exams, study load, intense pressure to succeed academically, accommodation problems, adjusting to new social and geographical environments and worries about the future (Heckman et al., 2014; Acharya et al., 2018) . The COVID-19 pandemic and the measures adopted against it such as school and university closures potentially caused novel, once-in-a-lifetime stressors and disruptions of daily life for most students worldwide, Therefore, as expected the Egyptian university students have been affected by the COVID-19 pandemic and its consequent public health measures with notable impact on their psychological status. Nearly, 70.5, 53.6 and 47.8% of the Egyptian students showed signs of psychological symptoms according to anxiety, depression and stress subscales, respectively. The prevalence were higher compared with a study using similar instruments among Turkish university students (Bayram and Bilgel, 2008) , where the prevalence of depression, anxiety and stress were 27.1, 47.1 and 27.0%, respectively. Another study among Malaysian university students showed that the prevalence of depression, anxiety and stress OR, odds ratio, CI, confidence interval. symptoms of moderate severity and above were 37.2, 63.0 and 23.7%, respectively (Shamsuddin et al., 2013) . Likewise, 24.9% of Chinese college students experienced anxiety because of the COVID-19 outbreak . Evidence from previous study documented that 18À20 years old individuals are vulnerable to mental illnesses and 75% of mental illnesses have first-time onset during the youth years (Downs et al., 2018) . For many students, commencing university is associated with leaving home for the first time, and increased independence, pressure, and responsibility (Verger et al., 2009 ). Farrer et al. (Farrer et al., 2016) stated that Australian students in their first year of study were at significantly greater risk of experiencing major depression. Additionally, Othman et al. (Othman et al., 2019) reported more anxiety among the initial year's students in a Canadian university. On contrary, the present study on the Egyptian students found no association between academic year and the level of depression, anxiety and stress. This could be attributed to the novel COVID-19 pandemic that affected the mental health of all students regardless of their academic year. The current study showed that female gender was associated with increased anxiety, depression and stress. This finding is in line with the results of previous studies Qiu et al., 2020; Mazza et al., 2020) , which have consistently found associations between female gender and increased psychological disturbance. This can be explained by the fact that females express their feelings as one of the ways to cope with stressful events and they are more liable to over complaint about physical and psychological symptoms (Amir and El Gillany, 2010; Shamsuddin et al., 2013) . Female gender has been identified as the most potent predictor of post-traumatic stress disorder symptoms after pandemics (Liu et al., 2020) . According to , anxiety disorder has been seen at three-fold higher levels in Chinese women than in men during the COVID-19 pandemic. Our findings showed that studying at medical colleges was associated with students' depression, the multivariable-adjusted OR (95% CI) was 1.46 (1.12À1.59). Evidence from several studies had shown that medical students worldwide experience significant rates of psychological distress and psychiatric morbidity (Puthran et al., 2016; Wilkes et al., 2019; Frajerman et al., 2019; Quek et al., 2019) . With a lot of uncertainty, accompanying the COVID-19 pandemic globally and its subsequent rapid changes in medical information there were many of the unprecedented public health measures. These measures included self-isolation, suspension of most of the life activities with the general lockdown including closure of the universities, canceled university practical and clinical lectures, practical exams and worries of the students, specially the medical ones regarding their academic progress and grades represented an extra burden, additional stress and significant psychological impact on the studied Egyptian university students. In line with our findings, a systematic review of 29 studies showed that the prevalence of anxiety and depression among students in medical schools in Europe, the UK and elsewhere in the English-speaking world outside of North America was 7.7À65.5 and 6.0À66.5%, respectively (Hope and Henderson, 2014) . Besides, as expected, our results show that Egyptian students who reported chronic diseases had higher odds to have stress, anxiety, and depression compared with healthy students. found that a medical history of chronic illness has been associated with higher levels of psychological distress among Chines population. Similar results were reported by Mazza et al. (Mazza et al., 2020) who studied the psychological distress among Italian people during the COVID-19 pandemic. A possible explanation for this result is that persons with a history of medical problems who also perceive their health as poor might feel more vulnerable to contracting a new disease (Hatch et al., 2018) . Students who had relatives or acquaintances infected with COVID-19 were about one and half times more likely to have depression, anxiety and stress than those who did not know affected person, which is consistent with the results of a study conducted by Cao et al. who found that having relatives or acquaintances infected with COVID-19 was a risk factor for increasing the anxiety of college students in China (OR ¼ 3.007, 95% CI ¼ 2.377À3.804). This might be related to the high contagiousness of the new COVID-19 (World Health Organization, 2020; Song et al., 2019) . High prevalence of psychological distress and its strong association with poor sleep quality amongst students was reported in previous studies; in Ethiopian (Lemma et al., 2012) , Malaysian (Shamsuddin et al., 2013) , Saudi Arabian (Aboalshamat et al., 2015) and Nigerian students (Seun-Fadipe and Mosaku, 2017). In accordance with previous findings, the current study found that sleeping adequate hours (6À9 h) per day was associated with lower depression, anxiety and stress scores. Spending more time to follow updates about the emerging COVID-19 pandemic was a significant predictor for the anxiety among the Egyptian students; OR ¼ 1.29 (1.04À1.62). The overwhelming and dramatic news headlines and erroneous news reports have added to anxiety and fear (Ayittey et al., 2020) . Additionally, our students cited that social media and internet websites were the main sources of their knowledge which requires attention that the unfiltered information broadcast by the news media and social media could explain their anxiety status. Recent reports demonstrated an association between frequent social media exposure and access to COVID-19 information and increased levels of depression and anxiety in the Chinese population during the COVID-19 pandemic . Worry feelings were also associated with exposure to COVID-19 information in social media, television and journals in India (Roy et al., 2020) . Therefore, avoidance to follow new stories about the COVID-19 pandemic can be considered as a good advice in order to escape its worse psychological impacts. Such avoidance of the worrying news of the pandemic has been identified as one of the behavioral coping methods employed during the severe acute respiratory syndrome epidemic, the Ebola epidemic and the H1N1 outbreak (Chew et al., 2020) . Finally, lack of support from family, community and university social support was associated with the depression, anxiety and stress of college Egyptian students, which is consistent with previous findings (Thompson et al., 2016; Chen et al., 2020; Cao et al., 2020) . This result suggests that effective and robust social support is necessary during public health emergencies. One of the major strengths of this study is that it includes a relatively large sample size that comprised students from different colleges from most of Egyptian universities all around the country. However, some limitations existed, which included the following; firstly, due to the cross-sectional nature of the study, it is difficult to determine the direction of effects and to determine whether any of the psychological impacts was a preexisting or a recently developed one. Longitudinal studies are needed to analyze the long-term impact of the new emerging pandemic on the psychological status of the students. Secondly, we adopted an online survey which may contribute to non-response bias in the study results. However, we believe that bias was potentially reduced by expanding the duration of the survey for $2 weeks, distribution of the questionnaire targeted most of the universities in Egypt through different social media platforms while avoiding to ask any question related to the students' identity or personal information. Thirdly, data about how the students spend their leisure time is lacking it might be a confounding factor that necessitates further research. In conclusion, Egyptian students experience varying levels of psychological disturbance during COVID-19 pandemic. Being a female, having a relative or acquaintance infected with COVID-19, having a preexisting chronic disease and lacking the psychological support from the family, the community and the university increase the risk of depression, anxiety and stress among Egyptian students. 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WHO, Geneva. World Health Organization. Novel coronavirus (2019-nCoV) Situation Report-12 Mental health services for older adults in China during the COVID-19 outbreak We acknowledge all Egyptian university students for their cooperation. None declared.