key: cord-1027819-mnoezqtx
authors: Asfuroglu Kalkan, E.; Ates, I.
title: A case of subacute thyroiditis associated with Covid-19 infection
date: 2020-06-05
journal: J Endocrinol Invest
DOI: 10.1007/s40618-020-01316-3
sha: da2601c9e2cb56774e310323edff62eafa52a601
doc_id: 1027819
cord_uid: mnoezqtx

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nasopharyngeal swab confirmed the diagnosis of Covid-19, two times. Chest X-rays and computed tomography scanning of the chest were normal. Thyroid ultrasound examination showed a relative diffuse decrease of vascularity and parenchyma was heterogeneous. Patient received hydroxychloroquine tablet 200 mg bid for 5 days. Prednisolone 16 mg daily was given and she showed significant improvement of clinical condition. She was discharged on prednisolone tapering dose for 4 weeks with outpatient follow-up.

The causal agent mainly based on serology, which made it difficult to differentiate between present and recent infection [3] . In this case, active infection with Covid-19 was confirmed since circulating viral genome was detected by RT-PCR.

A substantial number of patients with Severe Acute Respiratory Syndrome (SARS-CoV) have shown abnormalities in thyroid function. Follicular architecture was altered [4] . SARS could have harmful effect on the thyroid gland [5] .

Physician should be aware of screening subacute thyroiditis patients for Covid-19 infection.

Author contributions All authors had access to the data and a role in writing the manuscript.

Funding No funding was provided to any of the author.

Conflict of ınterest The authors declare that they have no conflict of interest.

Ethical Approval This article is a case report and written with the consent of the patient. Since this article is a case report, it does not contain any studies with animal or human participants performed by any of the authors.

Two-years prospective follow-up study of subacute thyroiditis. Front Endocrinol (Lausanne)

Subacute, silent, and postpartum thyroiditis

Viruses and thyroiditis. An update

Pathology of the thyroid in severe acute respiratory syndrome

Evaluation and observation of serum thyroid hormone and parathyroid hormone in patients with severe acute respiratory syndrome