key: cord-1023204-84e3p482 authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj title: Clinical Risk Score and COVID-19 date: 2021-04-05 journal: J Gen Intern Med DOI: 10.1007/s11606-021-06721-9 sha: 260c23629d1f12b71e2e684de17c1f8ae55fda39 doc_id: 1023204 cord_uid: 84e3p482 nan We would like to share ideas on the publication "Derivation of a Clinical Risk Score to Predict 14-Day Occurrence of Hypoxia, ICU Admission, and Death Among Patients with Coronavirus Disease 2019." 1 Levine et al. "A 3-item risk score for patients with COVID-19 consisting of age, oxygen saturation, and an acute phase reactant (albumin) using point of care data predicts suitability for discharge and may optimize scarce resources." 1 Regarding albumin, the background nutritional status should be considered. In many developing countries, malnutrition is common and whether it has any confounding effect on new score system is an interesting issue for further study. Second, the quality control of point of care testing is an important issue. 2 There are many possible interferences. For example, hemolysis can interfere albumin determination. 3 Derivation of a Clinical Risk Score to Predict 14-Day Occurrence of Hypoxia, ICU Admission, and Death Among Patients with Coronavirus Disease Recommendations and opinions for the use of point-of-care testing for hospitals and primary care: summary of a 1999 symposium Influence of hemolysis on routine clinical chemistry testing COVID-19 related immune hemolysis and thrombocytopenia