key: cord-1011876-2ycalf6b authors: Ribeiro, Heitor Siqueira; Wilund, Kenneth R.; Lima, Ricardo Moreno title: COVID-19 quarantine in chronic kidney disease patients: A focus on sarcopenia traits date: 2021-03-22 journal: J Bras Nefrol DOI: 10.1590/2175-8239-jbn-2020-0201 sha: 6fb6e1c7abe6b2c0ef8111e71cb5c2d3a5c1f574 doc_id: 1011876 cord_uid: 2ycalf6b nan Sarcopenia is defined by an age-related decline in muscle mass, strength, and physical function. It is known that people with CKD are at higher risk for sarcopenia, which is related to a systemic catabolic state, higher protein energy wasting, and other metabolic disorders 5 . As seen in Figure 1 , quarantine-related muscular disuse and inadequate dietary intake may potentially increase sarcopenia signs among people with CKD, a population that already presents with reduced functional reserve. People with CKD not yet in hemodialysis (HD) may be experiencing an even greater impact from quarantine than HD patients. In general, HD patients are still attending their dialysis clinics for scheduled treatments, so social isolation may not have impacted their routines to the same extent. Conversely, non-dialysis CKD patients do not have the same constraints, and they are generally more physically active. Thus, quarantine and social isolation due to COVID-19 may have a greater impact on their current lifestyle. The duration of social distancing that will be required for high risk individuals is not known, but the longer it lasts, the greater the impact it will likely have on the development and progression of sarcopenia in people with CKD around the world. Related consequences SarCopenia SCreening and Cut-off pointS aCCording to the european work group on SarCopenia in oLder peopLe (ewgSop2) Health professionals involved in the management of CKD need to consider strategies in order to mitigate the adverse effects of quarantine and social distancing on physical activity and musculoskeletal health. Exercise and nutrition interventions can potentially attenuate these adverse effects. Therefore, we encourage patients of all CKD stages to maintain or engage an active lifestyle, as well as adequate dietary intake during COVID-19 quarantine. To make these interventions safe and feasible, we recommend two guides: Coronavirus Disease 2019: Quick Diet and Nutrition Guide for Patients With Chronic Kidney Disease (https://www.jrnjournal.org/ article/S1051-2276(20)30213-2/fulltext) and My Get Active Guide (http://move.bangor.ac.uk/get-active.php. en), both available in Portuguese and English versions. HSR: drafted and wrote the manuscript. KRW and RML: reviewed and approved the final version. The Brazilian Society of Nephrology and the Covid-19 pandemic Prevalence and correlates of physical activity across kidney disease stages: an observational multicentre study COVID-19: a major cause of cachexia and sarcopenia Relationships between changes in self-reported physical activity, sedentary behaviour and health during the coronavirus (COVID-19) pandemic in France and Switzerland Clinical relevance of sarcopenia in chronic kidney disease Sarcopenia: revised European consensus on definition and diagnosis The authors have no conflicts of interest to declare.