key: cord-1010454-ulpjwpgd
authors: Williams, Eloise; Bond, Katherine; Zhang, Bowen; Putland, Mark; Williamson, Deborah A.
title: Saliva as a Noninvasive Specimen for Detection of SARS-CoV-2
date: 2020-07-23
journal: J Clin Microbiol
DOI: 10.1128/jcm.00776-20
sha: 1ff1d2b94aa7ee478fe390f9995e9fcd7d2b5c04
doc_id: 1010454
cord_uid: ulpjwpgd

Diagnostic testing for COVID-19 is central to controlling the global pandemic. ….

demonstrate the value of saliva as a noninvasive specimen for the detection of SARS-CoV-2. Although the sensitivity of saliva as a diagnostic specimen is less than NPS, saliva testing may be a suitable alternative first-line screening test in several environments, including low-resource settings, with NPS reserved for patients with an ongoing high clinical index of suspicion. These findings are highly relevant in the face of shortages of both swabs and personal protective equipment in many settings (5). 

Temporal profiles of viral load in posterior oropharyngeal saliva samples and serum antibody responses during infection by SARS-CoV-2: an observational cohort study

Comparison between saliva and nasopharyngeal swab specimens for detection of respiratory viruses by multiplex reverse transcription-PCR

Isolation and rapid sharing of the 2019 novel coronavirus (SARS-CoV-2) from the first patient diagnosed with COVID-19 in Australia

Consistent detection of 2019 novel coronavirus in saliva

Critical supply shortages-the need for ventilators and personal protective equipment during the Covid-19 pandemic