key: cord-1001041-2eab6g7i
authors: Chen, Taige; Lu, Xiaofan; Wang, Yang; Wang, Jun
title: Lessons from a patient with severe aplastic anemia complicated with COVID-19
date: 2020-07-20
journal: Asian J Surg
DOI: 10.1016/j.asjsur.2020.07.007
sha: bc75ac89473bbab1f33c8cf3faa204bcb7cc2e42
doc_id: 1001041
cord_uid: 2eab6g7i

COVID-19 patients with preexisting diseases are at high risk of worse clinical outcomes. There is little data about patients with different comorbidities and how to deal with them. We reported a case of a patient with severe aplastic anemia complicated with COVID-19 who improved but turned worse rapidly and died in septic shock.

Competing interests 152 The authors declare that they have no competing interests. To our knowledge, patient with COVID-19 complicated with SSA is quite rare, 65 and this case report reminds us that atypical or even asymptomatic manifestations of

Double First-Class" University project (CPU2018GY09), the Science Foundation of 122

Jiangsu Commission of Health (H2018117), and the Emergency Project for the 123

Prevention and Control of the Novel Coronavirus Outbreak in Suzhou (SYS2020012)

The funders had no role in the design and conduct of the study; collection, 126 management, analysis, and interpretation of the data; preparation, review, or 127 approval of the manuscript; and decision to submit the manuscript for publication

Authors' Contributions

Wang had full access to all of the data in the study

Chen contributed equally and share first authorship

Acquisition, analysis, or interpretation of data

136 Funding acquisition

Clinical course and outcomes of 344 intensive care 147 patients with COVID-19. American journal of respiratory and critical care medicine

Lianhuaqingwen exerts anti-viral and 150 anti-inflammatory activity against novel coronavirus (SARS-CoV-2)

Current concepts in the pathophysiology 153 and treatment of aplastic anemia

Aplastic anaemia. The Lancet

159 showing two nodule-like shadows on the right lung with blurred borders (A), and 160 another shadow on the lower left lung (B)

COVID-19 may be disguised by inherent diseases. We call upon all the medical 67 personnel to pay specific attention to original comorbidities, and patients with SSA 68 needs early prevention of septic shock to improve overall outcome.