key: cord-0998378-runllmpl
authors: Takahashi, Ken; Sato, Taisuke; Kamide, Taizan; Hoshina, Tokio; Kanuka, Hirotaka; Kumazawa, Kensuke; Tanabe, Yukitoshi; Samura, Osamu; Okamoto, Aikou
title: Perinatal management of a pregnant woman with COVID-19: A case report from Japan
date: 2022-02-11
journal: Taiwan J Obstet Gynecol
DOI: 10.1016/j.tjog.2022.02.033
sha: 036cc60c36d11a458f847970c445dfa37d02400b
doc_id: 998378
cord_uid: runllmpl

Objective Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has caused the coronavirus disease 2019 (COVID-19) pandemic. Owing to limited information, the impact and clinical course of COVID-19 in pregnant women and newborns remain unclear. Here, we report the clinical course of a full-term pregnant woman with COVID-19 and her newborn. Case report A 27-year-old pregnant woman with a fever and sore throat was diagnosed with COVID-19. To prevent and control SARS-CoV-2 infection to the newborn and medical staff, delivery was performed via cesarean section. Reverse-transcription quantitative polymerase chain reaction results of the placenta, umbilical cord, cord blood, amniotic fluid, vaginal fluid, breastmilk, newborn anal wipes, and nasopharyngeal samples were negative for SARS-CoV-2. An acute increase in maternal blood pressure and HELLP syndrome-like blood data fluctuations were observed after delivery. Conclusion Perinatal management of patients with COVID-19 could be safely performed for medical staff and newborns under adequate infection control measures.

A concern in COVID-19 postpartum management is newborn isolation and 169 breastfeeding practices. We isolated the newborn from the mother until negative RT- 

Diagnostic detection of Wuhan coronavirus 2019 by real-time 218

Antibodies in infants born to 220 mothers with COVID-19 pneumonia

SARS-CoV-2 infection of the placenta

SARS-CoV-2 can infect the placenta and is not associated with specific placental 225 histopathology: a series of 19 placentas from COVID-19-positive mothers