key: cord-0991022-sizyxa0b authors: Yıldırıcı, Şebnem; Yaylı, Savaş; Demirkesen, Cüyan; Vural, Seçil title: New onset of pemphigus foliaceus following BNT162b2 vaccine date: 2022-02-23 journal: Dermatol Ther DOI: 10.1111/dth.15381 sha: 54911005442797cde1ff2b8e40c2503be74998ff doc_id: 991022 cord_uid: sizyxa0b nan Dear Editor, A 65-year-old man was referred to the dermatology clinic with blisters. The lesions started one week ago as multiple lesions with scaling on his chest, back and scalp ( Figure 1 ). Oral mucosa was normal. One month ago, the patient had the BNT162b2 mRNA COVID-19 vaccine (Comirnaty, Biontech/Pfizer). He had hypertension for 10 years, and he has been using nebivolol 5 mg/day orally. A pill containing valsartan-hydrochlorothiazide combination was added to the treatment four months ago. Informed consent was obtained from the patient. Lesional biopsy with hematoxylin-eosin stain showed intra- Covid-19 and autoimmunity Aggressive course of pemphigus vulgaris following COVID-19 infection Pemphigus vulgaris after COVID-19: a case of induced autoimmunity Potential antigenic cross-reactivity between SARS-CoV-2 and human tissue with a possible link to an increase in autoimmune diseases The first dose of COVID-19 vaccine may trigger pemphigus and bullous pemphigoid flares: is the second dose therefore contraindicated? Subepidermal blistering eruptions, including bullous pemphigoid, following COVID-19 vaccination Development of severe pemphigus vulgaris following SARS-CoV-2 vaccination with BNT162b2 Oral pemphigus after COVID-19 vaccination Valsartan/hydrochlorothiazide induced pemphigus foliaceus