key: cord-0988903-11v9i0qf
authors: Barbati, Giovanni; Erente, Giovanna; Magagna, Paolo; Spigolon, Luca; Caprioglio, Francesco
title: Multi-modality imaging of post-myocardial infarction ventricular septal defect associated to basal inferoseptal pseudoaneurysm
date: 2021-09-15
journal: J Echocardiogr
DOI: 10.1007/s12574-021-00551-8
sha: bebafd0cc800cc7c2c53eb6b17193650ebd73ae1
doc_id: 988903
cord_uid: 11v9i0qf

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An 84 year-old man, admitted in Intensive Cardiac Care Unit during the COVID-19 pandemic for late presenting inferoposterior myocardial infarction (MI), showed an holosystolic murmur along left sternal border consistent with suspected intracardiac shunt at focused cardiac ultrasound. Coronary angiography detected a thrombotic occlusion of distal right coronary artery and ventriculography revealed a large basal inferoseptal aneurysm associated to left-to-right shunt (Fig. 1a) . After consulting heart team, it was decided to treat right coronary occlusion with angioplasty and stent implantation, postponing the defect treatment in the next days. Transthoracic echocardiography (TTE) clearly displayed that it was a huge pseudoaneurysm with a wide neck, associated to a ventricular septal defect with a significant left-to-right shunt ( Fig. 1b and 1c , Video 1 of the electronic supplementary material), calculated QP/QS of 1,9 and transventricular gradient of 72 mmHg (Fig. 1d ). 3D TTE, using a photorealistic rendering, gave the possibility to navigate into the lesions with an en-face perspective (Fig. 1e , f) and to reconstruct their dimensions with a multiplanar approach (Video 2 of electronic supplementary material). The neck of the pseudoaneurysm resulted 21 × 22 mm, whilst the ventricular septal defect measured 8 × 10 mm. To further best characterize these lesions to attempt a percutaneous closure, we performed a computed tomography (Fig. 1g) , from which a 3D plastic model was obtained (Fig. 1h) . After 18 days from percutaneous coronary intervention, the patient underwent percutaneous closure of defects. Despite treatment, post-operative course was complicated by cardiogenic shock due to right heart failure, consequence of right ventricle involvement in late presenting inferoposterior myocardial infarction and of left-to-right shunt, which eventually led to patient demise for multiorgan failure after eight days from intervention.

During COVID-19 pandemic we are assisting to an increase of post-MI mechanical complications [1] . Ventricular septal defect associated to left ventricular pseudoaneurysm represents a rare and life-threatening mechanical complication of late presenting MI [2, 3] . Few cases are described in literature and the optimal treatment is debating. Using multi-modality imaging is mandatory to optimally define the anatomy before attempting a percutaneous or surgical treatment. 3D printing models, particularly, can be very attracting and useful for deep understanding of morphology of such complex cardiac defects. giving the possibility to navigate into the lesions (e and f); computed tomography image of defects (g) and 3D plastic model (h) obtained to best characterize them; ventricular septal defect (yellow arrow); pseudoaneurysm (white asterisk)

COVID-19 pandemic is associated with mechanical complications in patients with ST-elevation myocardial infarction

Left ventricular pseudo-false aneurysm perforating into the right ventricle

CT imaging of postmyocardial infarction ventricular septal defect with a contained rupture/pseudoaneurysm

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