key: cord-0987455-rhs80qtc
authors: Seeliger, Barbara; Pessaux, Patrick
title: SARS-CoV-2 RNA in peritoneal fluid of COVID-19 patients – prevalence and significance
date: 2021-02-16
journal: Surgery
DOI: 10.1016/j.surg.2021.02.025
sha: 818b927b6f4b91eb17f4680e2673d8051a87eea9
doc_id: 987455
cord_uid: rhs80qtc

nan

Surgery carries a high risk of morbidity and mortality, and only emergency procedures should be performed during acute COVID-19 infections. Consequently, patients amenable to analysis of intraperitoneal SARS-CoV-2 presence are rare.

Intraperitoneal viral RNA detection was reported in four COVID-19 patients only.

Intraperitoneal swab testing 3, 4 , intraoperative fluid sampling 5 and PD effluent 6 enabled SARS-CoV-2 RNA detection by RT-PCR. The PD effluent remained SARS-CoV-2 positive, associated with peritoneal membrane malfunction (PD failure) 6 It remains unclear whether viral RNA detection is equivalent to presence of contagious virus 6 . The majority of articles on intraperitoneal coronavirus detection concern FIP, where RT-PCR performed on effusions has a high specificity, and a RT-PCR assay was developed to identify actively replicating virus by detecting its 

Is the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) present intraperitoneally in patients with coronavirus disease 2019 (COVID-19) infection undergoing emergency operations?

COVID-19) hospitalized patients with acute kidney injury treated with acute peritoneal dialysis do not have infectious peritoneal dialysis effluent

SARS-CoV-2 is present in peritoneal fluid in COVID-19 patients

SARS-Cov-2 in peritoneal fluid: an important finding in the Covid-19 pandemic

COVID-19 in the peritoneal fluid: does this evidence oblige to introduce new rules? Presentation of a Case Report

SARS-CoV-2 in the peritoneal waste in a patient treated with peritoneal dialysis

Diagnosis of Feline Infectious Peritonitis: A Review of the Current Literature

Feline infectious peritonitis (FIP) and coronavirus disease 19 (COVID-19): Are they similar? Transbound Emerg Dis