key: cord-0984035-u2pdoyiy authors: Acharya, Krishna P.; Subramanya, Supram H.; Neupane, Dinesh title: Emerging pandemics: Lesson for one‐health approach date: 2020-10-08 journal: Vet Med Sci DOI: 10.1002/vms3.361 sha: c6c625a7c8f669e75340dfbf92559f2a408b8157 doc_id: 984035 cord_uid: u2pdoyiy nan spread of SARS from bats to civets to humans (Guan et al., 2003) , spread of MERS-CoV from vespertilionid bats to camelids to humans (Corman et al., 2014) and the close relatedness of SARS-CoV-2 to bat and pangolin viruses (Lau et al., 2020; Wu et al., 2020; Zhou et al., 2020) . Over 30 new human pathogens have emerged in the last three decades, 75% of which have originated in animals (Jones et al., 2008) . Animal borne emerging infectious diseases can cause significant economic shocks. More than 75% of new or emerging infectious diseases spreads from animals to humans (anthropozoonoses) through various routes (FAO & USAID, 2019; Munyua et al., 2019) . Interestingly, some of the common pathogens of humans such as Mycobacterium tuberculosis, Cryptosporidium parvum, Ascaris lumbricoides can be transmitted from humans to animal populations (zooanthroponoses) (Messenger et al., 2014) . The transmission of pathogens between animals and humans requires target control measures/interventions (Ajit, 2019) . The close relationship between animals and humans can increase the risk for transmission of drug-resistant infections. Due to the intimate human animal-environmental interface, controlling these epidemics/ pandemics requires multi-sectoral collaboration between numerous disciplines, which suggests a One-Health approach to understand the biological, social, environmental and genetic determinants of health and diseases of humans and animals (Mackenzie & Jeggo, 2019) . To prevent and control these emerging diseases, we may need to develop more advanced systems such as genomic precision surveillance platforms that help to detect and report the cases of outbreaks on time (Acharya et al., 2019) . For complex monitoring and policy interventions, an inter-sectoral health system collaboration is required. In particular, communication at regional, national and international levels across the onehealth sectors to limit the impact of these changes on the health of all (FAO & USAID, 2019) . The large scale implementation of the One-Health approach is limited; a few projects have been effectively implemented in outbreaks, for example, to prevent river blindness (Onchocerciasis) (Cantey et al., 2018; Voegele & Kemper, 2018) in Africa and Avian Influenza in Asia (The World Bank, 2011) and Africa (Dixit, 2015) . The One-Health approach can be highly efficient in terms of resource-use efficiency. An analysis by the World Bank suggested strengthening human and animal health capacity by the One-Health approach could result in 10%-30% cost saving in surveillance and communication cost (World Bank, 2012) . A study by Rostal et al., in sub-Saharan Africa, on the prevalence of Rift Valley Fever (RVF), demonstrated that the One-Health surveillance system was effective in detecting cases of RVF. It was concluded that these cases would have likely been missed with traditional surveillance systems (Rostal et al., 2018) . Economic analysis of this risk reduction and early detection, demonstrated a cost saving of 35% (Rostal et al., 2018) . Qatar has successfully combated MERS-CoV through active surveillance, inter-sectoral collaboration and joint investigation through the One-Health approach (Farag et al., 2019) . A similar study using a One-Health approach with an integrated human and animal disease laboratory in Winnipeg, Canada demonstrated cost savings of 26% per year (World Bank, 2012). Thus, implementation of One-Health approach carries a potential for the prevention and control of trans-boundary zoonotic diseases, such as Avian Influenza, Swine Influenza, SARS, MERS, Q-fever and COVID-19 efficiently and cost-effectively. Often, the public health authority, however, remiss the significance of animal and environmental health sectors, as a result, it has been challenging to control such pandemics. Till now, holistic systems of integrating human health, animal health and environment-related disciplines have not been implemented. Thus, we are failing to understand the pivotal role of animal and environmental health sectors to prioritize the "One-Health" approach. It is essential to prepare all the countries for possible future pandemics by appropriate allocations of financial resources, international collaboration, strengthening the veterinary services and public health systems. That needs a financing mechanism to disburse the required funds for a rapid and effective response to pandemics (Voegele & Kemper, 2018) . This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited. © 2020 The Authors Veterinary Medicine and Science Published by John Wiley & Sons Ltd Combatting antimicrobial resistance in Nepal: The need for precision surveillance programmes and multi-sectoral partnership Emergence and control of zoonotic diseases in India Transitioning from river blindness control to elimination: steps toward stopping treatment Pandemic (H1N1 virus)|Pandemic Influenza (Flu)|CDC. Centers Dis How Taiwan beat the coronavirus Rooting the phylogenetic tree of middle east respiratory syndrome coronavirus by characterization of a conspecific virus from an African bat Controlling avian flu in west africa: nuclear-derived techniques enable early detection of outbreaks Qatar experience on One Health approach for middle-east respiratory syndrome coronavirus Isolation and characterization of viruses related to the SARS coronavirus from animals in Southern China Global trends in emerging infectious diseases Possible bat origin of severe acute respiratory syndrome coronavirus 2 The one health approach-Why is it so important? Reverse zoonotic disease transmission (Zooanthroponosis): A systematic review of seldom-documented human biological threats to animals Successes and challenges of the One Health approach in Kenya over the last decade What we can learn from Taiwan's response to the COVID-19 epidemic Benefits of a one health approach: An example using Rift Valley fever. One Health 1918 influenza: the mother of all pandemics Avian influenza control and human pandemic preparedness and response (APL) project One health approach is critical to derisk human, animal and environmental health A new coronavirus associated with human respiratory disease in China A pneumonia outbreak associated with a new coronavirus of probable bat origin