key: cord-0983273-ohrkv9gw authors: Zeng, Lin; Zang, Feng; Song, Ninghong; Li, Zhanjie title: Analysis of influenza trend and impact of COVID‐19 in Kezhou, Xinjiang for 8 consecutive years date: 2022-03-20 journal: J Med Virol DOI: 10.1002/jmv.27678 sha: 2c12123045301921bc2fda95aff44712adae8e93 doc_id: 983273 cord_uid: ohrkv9gw To study the trend of influenza and the impact of coronavirus disease 2019 (COVID‐19) in Kezhou, Xinjiang from 2013 to 2020. The data of influenza in Kezhou, Xinjiang from January 1, 2013, to December 31, 2020, were collected by the China Influenza Surveillance Information System to study the trend of ILI proportion, the distribution of influenza‐like cases in different age groups, the positive cases and positive rate of influenza, and the trend of different influenza subtypes, and to analyze the impact of COVID‐19 epidemic on influenza. The proportion of ILI in the Xinjiang Kezhou area was mainly children under 15 years old, and children under 5 years old accounted for the largest proportion. The proportion of ILI, the number of influenza‐positive cases, and the influenza‐positive proportion were mainly in winter and spring, especially in December and January each year. At the same time, this study found that the overall trend of H3N2 influenza in this region was on the rise, and the outbreaks in 2018 and 2019 were dominated by novel H1N1 and H3N2, respectively. The trend of influenza in Kezhou, Xinjiang is on the rise, and the prevention and control measures of COVID‐19 have significantly reduced the data of influenza. It is necessary to strengthen the vaccination work and maintain the basic prevention and control measures of respiratory infectious diseases to prevent and control influenza more effectively. The outbreak of coronavirus disease 2019 (COVID-19) has rapidly developed into a worldwide pandemic. 1 The virus is highly transmitted among people and spreads rapidly, 2 resulting in huge health threats and socioeconomic losses. The prevention and control of respiratory infectious diseases have received increasing recognition. 3, 4 Influenza (or Flu), a kind of acute respiratory infectious disease caused by the influenza virus, is characterized by a short incubation period, strong infection, and rapid spread, which seriously endangering people's health. At present, people have been mainly infected with H1N1 and H3N2 subtypes of influenza A virus and Victoria and Yamagata strains of influenza B virus. 5 Globally, seasonal influenza is associated with high morbidity and mortality each year. 6 It is estimated that influenza causes about 290 000 to 650 000 respiratory-related deaths every year, which is an increase from the previous estimate of about 250 000-500 000 respiratory and circulatory-related deaths every year. 7 Consequently, influenza has become a prominent public health issue of global concern, and also the first infectious disease that needs Influenza virus is the major cause of human acute respiratory diseases and has led to several serious global pandemics due to its transmission dynamics and antigenic variability. 9 In September 2020, the comprehensive group dealing with novel coronavirus which is consistent with the results of domestic research works. 11, 12 The major reason is that children have relatively weak immunity and hence become the main infected object of influenza. 13 The proportion of ILI, the number of positive cases, and the proportion of positive cases in this region were mainly in winter and spring, especially from December to January every year. Relevant studies at home and abroad have provided evidence of the correlation between low temperature in winter and influenza. 14 However, such seasonal distribution is different from the influenza trend presenting a stable single peak in winter in Shandong, Gansu, and other northern provinces north of Qinling Mountain-Huaihe River, 11,12 but it is basically consistent with the trend in other regions of Xinjiang provinces proposed in relevant studies. 15, 16 In addition to winter, there is also an influenza peak in spring, which may be related to the fact that Xinjiang is more vulnerable to the invasion of the influenza virus due to changeable weather and heavy sandstorm in spring. 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Project supported by the National Science The authors declare no conflicts of interest. An ethics statement was not required for this study type, no human or animal subjects were used.