key: cord-0981799-1u1gh86i authors: Novazzi, Federica; Baj, Andreina; Genoni, Angelo; Spezia, Pietro G.; Colombo, Alberto; Cassani, Gianluca; Zago, Cristian; Pasciuta, Renee; Della Gasperina, Daniela; Ageno, Walter; Severgnini, Paolo; Dentali, Francesco; Focosi, Daniele; Maggi, Fabrizio title: SARS‐CoV‐2 B.1.1.7 reinfection after previous COVID‐19 in two immunocompetent Italian patients date: 2021-05-15 journal: J Med Virol DOI: 10.1002/jmv.27066 sha: 2d9ca8439ff1c07731085e550c1496a3099c4e56 doc_id: 981799 cord_uid: 1u1gh86i To date only one case of SARS-COV-2 B.1.1.7 reinfection has been reported (1). We report here two more such reinfection cases in Lombardy residents that, nevertheless the ECDC statement of a period from 45 to 90 days to confirm a reinfection (2), experimented a second infection from a B.1.1.7 variant of SARS CoV-2 only one month after the first one. In both cases interstitial pneumonia requiring intubation or oxygen support was present at the time of first infection, whereas the second one was characterized by very mild development. This article is protected by copyright. All rights reserved. 20I/501Y.V1, B.1.1.7, COVID-19, SARS-CoV-2, UK variant, variant of concern, VOC 202012/01 To date, only one case of SARS-COV-2 B.1.1.7 reinfection has been reported. 1 We report here two more such reinfection cases in Lombardy residents that, nevertheless the ECDC statement of a period from 45 to 90 days to confirm reinfection, 2 experimented a second infection from a B.1.1.7 variant of SARS-CoV-2 only 1 month after the first one. In both cases, interstitial pneumonia requiring intubation or oxygen support was present at the time of the first infection, whereas the second one was characterized by very mild development. Confirmed reinfection with SARS-CoV-2 variant VOC-202012/01 European Centre for Disease Prevention and Control. Reinfection with SARS-CoV-2: implementation of a surveillance case definition within the EU/EEA. Stockholm: European Centre for Disease Prevention and Control Imported SARS-COV-2 variant P.1 in traveler returning from Brazil to Italy COVID-19 Mobility Data Network International risk of the new variant COVID-19 importations originating in the United Kingdom The effect of SARS-CoV-2 variant B.1.1.7 on symptomatology, re-infection and transmissibility. medRxiv How to cite this article SARS-CoV-2 B.1.1.7 reinfection after previous COVID-19 in two immunocompetent Italian patients