key: cord-0965710-i4owbvsi authors: Mountantonakis, Stavros E.; Saleh, Moussa; Coleman, Kristie; Kuvin, Jeffrey; Singh, Varinder; Jauhar, Rajiv; Ong, Lawrence; Qiu, Michael; Epstein, Laurence M. title: Out-of-Hospital Cardiac Arrest and Acute Coronary Syndrome Hospitalizations During the COVID-19 Surge date: 2020-09-08 journal: J Am Coll Cardiol DOI: 10.1016/j.jacc.2020.07.021 sha: 963aff213e522b5e16e655101d86f3a69ced12c2 doc_id: 965710 cord_uid: i4owbvsi nan normal resting value. The typical situation where this phenomenon is important is in patients admitted for an acute myocardial infarction and multivessel disease, especially when cardiogenic shock is present. Performing immediate percutaneous coronary intervention (PCI) of a nonculprit lesion supplying a normally contracting segment offers no potential immediate benefit (i.e., resting myocardial perfusion and regional wall motion will not improve). In contrast, additional catheter manipulation and immediate multivessel PCI at the acute stage translated in higher death rates than PCI of the culprit lesion only as demonstrated in the CULPRIT-SHOCK (The Culprit Lesion Only PCI versus Multivessel PCI in Cardiogenic Shock) trial (4) . Staged procedures for nonculprit stenoses might prevent a future event and will likely increase hyperemic flow, but are unlikely to improve resting flow or regional wall motion (5) . Interim Guidance for Implementing Home Care of People Not Requiring Hospitalization for Coronavirus Disease 2019 (COVID-19). Available at: cdc.gov/COVID19 Reduction in ST-segment elevation cardiac catheterization laboratory activations in the United States during COVID-19 pandemic Out-of-hospital cardiac arrest during the Covid-19 outbreak in Italy COVID-19 Data SCAI expert consensus statement on out of hospital cardiac arrest