key: cord-0961729-3u3xxbvl
authors: Ray, Debadrita; Mallik, Nabhajit; Sreedharanunni, Sreejesh; Jain, Arihant; Bal, Amanjit; Sachdeva, Man Updesh Singh
title: Leukemic presentation with discordant morphology in triple‐hit lymphoma—A diagnostic pitfall during COVID‐19 pandemic
date: 2021-06-04
journal: Int J Lab Hematol
DOI: 10.1111/ijlh.13616
sha: 2df2fe074cfbd2175ceb2ea2c2942a71d1756ac4
doc_id: 961729
cord_uid: 3u3xxbvl

nan

As the pandemic rears on, virological testing for COVID-19 in all patients prior to each invasive procedure becomes logistically demanding in resource-poor settings. Invasive diagnostic procedures are thus often being avoided if adequate information can be gleaned from noninvasive tests. However, deviation from well-established investigative algorithms may lead to unnecessary diagnostic confusion with potentially serious consequences, as we discovered in the case described below.

A 33-year-old man presented with pain abdomen, loss of appetite, weight loss, and generalized lymphadenopathy for 3 months.

Abdominal imaging showed conglomerated retroperitoneal lymphnodal mass and intestinal mural thickening. Complete blood count re- 

High-grade B-cell lymphoma with MYC and BCL2 and/or BCL6 rearrangements with diffuse large B-cell lymphoma morphology

Impact of induction regimen and stem cell transplantation on outcomes in doublehit lymphoma: a multicenter retrospective analysis

Front-line, doseescalated immunochemotherapy is associated with a significant progression-free survival advantage in patients with double-hit lymphomas: a systematic review and meta-analysis

Leukemic presentation of high-grade B cell lymphoma with MYC and BCL2 rearrangement-a series of two cases and review of literature

Double-hit and triple-hit follicular lymphoma: case series and review of 40 cases

Discordant bone marrow involvement in diffuse large B-cell lymphoma: comparative molecular analysis reveals a heterogeneous group of disorders

Discordant bone marrow involvement in diffuse large-cell lymphoma: a distinct clinicalpathologic entity associated with a continuous risk of relapse

Bone marrow involvement in large-cell lymphoma: prognostic implications of discordant disease

Clinical and prognostic significance of monoclonal small cells in the peripheral blood and bone marrow of various B-cell lymphomas

Discordant morphologic features in bone marrow involvement by malignant lymphomas: Use of gene rearrangement patterns for diagnosis