key: cord-0960808-k2balze9 authors: Yadav, Pragya D.; Sahay, Rima R.; Agrawal, Sachee; Shete, Anita; Adsul, Balkrishna; Tripathy, Srikanth; Nyayanit, Dimpal A.; Manrai, Manish; Patil, Deepak Y.; Kumar, Sanjay; Marwah, Vikas; Sapkal, Gajanan N.; Shastri, Jayanthi; Viswanathan, Rajlakshmi; Pandit, Priyanka; Mishra, Yogendra; Chavan, Smita; Joshi, Yash; Kumar, T Ajai; Majumdar, Triparna; Kumar, Abhinendra; Patil, Savita; Munshi, Renuka; Desai, Unnati; Kaushal, Himanshu; Suryawanshi, Annasaheb; Dudhmal, Manisha; Gawande, Pranita; Jain, Rajlaxmi; Waghmare, Ashwini; Kalele, Kaumudi; Vedpathak, Pratiksha; Yemul, Jyoti; Bodke, Poonam; Kore, Tejashri; Kakrani, A.L.; Athavale, Prachi; Suryawanshi, Poonam; Patsute, Sudhir; Padbidri, Vikram; Awate, Pradip; Abraham, Priya title: Clinical, immunological and genomic analysis of the post vaccinated SARS-CoV-2 infected cases with Delta derivatives from Maharashtra, India, 2021 date: 2022-04-08 journal: J Infect DOI: 10.1016/j.jinf.2022.04.014 sha: 6608d8d025a2cbca63baa011a3033cab045f69ff doc_id: 960808 cord_uid: k2balze9 nan Of the 448 infected cases, male were predominant (44-65%) in all the four groups. Diabetes Mellitus type-II was the most common co-existing illness/co-morbidity (22-35%) ranging from, followed by hypertension (20-35%) asthma (2-11%) and obesity (2-7.5%) in all groups. Of all the cases, 77 to 88% cases were hospitalized, while 2.5-22% was at home 4 isolation. Of all the cases, 338 (75.44%) cases were mild while 90 (20.04%) and 20 (4.46%) cases were moderate and severe respectively. Most of the cases were mild (55-82%), while 11% in CVSD and 6.71% in CSSD were severe as compared to the CVDD (5%) and CSDD Authors do not have a conflict of interest among themselves. Impact of time elapsed since full vaccination on SARS-CoV-2 RNA load in Delta-variant breakthrough COVID-19 Vaccine Breakthrough Infections with SARS-CoV-2 Variants SARS-CoV-2 spike mutations, L452R, T478K, E484Q and P681R, in the second wave of COVID-19 in Maharashtra COVID-19 Vaccine Breakthrough Infections Reported to CDC-United States Genomic Survey of SARS-CoV-2 Vaccine Breakthrough Infections in Healthcare Workers from Kerala Predominance of delta variant among 7 the COVID-19 vaccinated and unvaccinated individuals Breakthrough COVID19 Infections after Vaccinations in Healthcare and Other Workers in a Chronic Care Medical Facility Clinical Characterization and Genomic Analysis of Samples from COVID-19 Breakthrough Infections during the Second Wave among the Various States of India The authors would like to gratefully acknowledge the staff of ICMR-NIV, Pune including Shilpa Ray for extending the excellent technical support. We thank to all study participants.