key: cord-0960150-vrmjxazu authors: Chen, Tai-Heng title: Neurological involvement associated with COVID-19 infection in children date: 2020-08-13 journal: J Neurol Sci DOI: 10.1016/j.jns.2020.117096 sha: fa38066e56bb3c558c91c8027c1e8b51719b825f doc_id: 960150 cord_uid: vrmjxazu nan in as high as 54% of the affected children [12] . The high incidence of neurological complications in children with MIS-C Kawasaki-like disease remains unclear; nevertheless, the mechanism might be different from the thromboembolic mechanism of the cerebrovascular system observed frequently in adult COVID-19 patients. In these MIS-C cases, 46% and 92% of children were reported positive COVID-19 reverse transcription polymerase chain reaction (RT-PCR) and serum antibody (IgG and/or IgM), respectively. This evidence suggests that while MIS-C occurred, most children might not have an active COVID-19 infection (Table 1) Central nervous system manifestations of COVID-19: A systematic review The neurology of COVID-19 revisited: A proposal from the Environmental Neurology Specialty Group of the World Federation of Neurology to implement international neurological registries Coronavirus Infection in Pediatric Emergency Departments Research, Children with Covid-19 in Pediatric Emergency Departments in Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease Chinese Pediatric Novel Coronavirus Study Paediatric multisystem inflammatory syndrome temporally associated with SARS-CoV-2 mimicking Kawasaki disease (Kawa-COVID-19): a multicentre cohort Kawasaki-like multisystem inflammatory syndrome in children during the covid-19 pandemic Multisystem Inflammatory Syndrome in Children during the COVID-19 pandemic: a case series An outbreak of severe Kawasaki-like disease at the Italian epicentre of the SARS-CoV-2 epidemic: an observational cohort study Multisystem Inflammatory Syndrome in Children in New York State