key: cord-0959099-kcm4fqr6 authors: Aponso, Shashendra; Hoou, Loh Chee; Wei, Yeo Yi; Salahuddin, Syed Ahmed; Yit, Pan Jiun title: Multibacillary leprosy unmasked by COVID-19 vaccination. date: 2021-11-24 journal: JAAD Case Rep DOI: 10.1016/j.jdcr.2021.11.011 sha: 54f98b63e15590815574251e4d3ca0756d8201e0 doc_id: 959099 cord_uid: kcm4fqr6 nan Leprosy is a chronic, disfiguring infectious disease. It is traditionally classified into either 34 tuberculoid (paucibacillary) leprosy or lepromatous (multibacillary) leprosy, which differ in 35 the number of bacteria present in the skin and clinical manifestations. Patients in between the 36 two types are classified as borderline. In the context of the COVID-19 pandemic, patients 37 with leprosy will also receive the COVID-19 vaccination. Here we describe a case of Immunology of leprosy and diagnostic challenges Safety and Efficacy of the BNT162b2 mRNA Covid-128 COVID-19 vaccines: modes of immune activation and future 130 challenges COVID-19 vaccine BNT162b1 elicits human 132 antibody and TH1 T cell responses Delayed Large Local Reactions to mRNA-1273 Vaccine against SARS-CoV-2 Immune 136 reconstitution inflammatory syndrome after cessation of the tumor necrosis factor alpha blocker 137 adalimumab in cryptococcal pneumonia Paradoxical response to 139 antituberculous therapy in infliximab-treated patients with disseminated tuberculosis Recognizing and managing the immunologic 142 reactions in leprosy Leprosy -an overview of clinical features, diagnosis, and treatment