key: cord-0954862-m5c6a5ht
authors: Sinadinos, Angela; Shelswell, Jonathan
title: Oral ulceration and blistering in patients with COVID-19
date: 2020-06-26
journal: Evid Based Dent
DOI: 10.1038/s41432-020-0100-z
sha: 12becfb60b5cc931dc03eb3b8f16324764d61ed2
doc_id: 954862
cord_uid: m5c6a5ht

Design Case series. Introduction The most common signs and symptoms of SARS-CoV-2 infection include headache, sore throat, hyposmia, hypogeusia, diarrhoea, dyspnoea and pneumonia. Dermatological manifestations have also been reported but few authors have documented oral signs and symptoms. Methods Three cases are reported where oral ulceration or blistering is found in patients with confirmed or suspected COVID-19. Results One patient had serologically confirmed COVID-19, whilst the remaining two cases were only suspected. Two patients reported pain from the palate, whilst the third reported in the tongue. The first two patients had lesions affecting keratinised tissue consistent with herpes simplex lesions but with no history of herpetic infection. The third patient had lesions compatible with erythema multiforme. Conclusions The authors suggest a link between COVID-19 and oral ulceration and blistering, but acknowledge these signs may often go undetected due to a lack of intraoral examination during hospital admission.

The third patient had lesions compatible with erythema multiforme.

The authors suggest a link between COVID-19 and oral ulceration and blistering, but acknowledge these signs may often go undetected due to a lack of intraoral examination during hospital admission.

Multiple manifestations of SARS-CoV-2 infection have been described in the literature to date. The most common signs and symptoms are headache, sore throat, hyposmia, hypogeusia, diarrhoea, dyspnea, and pneumonia. 1 Authors have also described cases with dermatological manifestations. 2 This case series describes three patients presenting with oral manifestations. 3 One of these patients had confirmed COVID-19 infection, and two patients were awaiting serological testing to confirm this. All three patients were examined by video consultation, and all cases presented with ulceration or blistering in the oral cavity. 

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Cutaneous manifestations in COVID19: a new contribution

Oral vesiculobullous lesions associated with SARS-CoV-2 infection

• Intraoral symptoms in COVID patients is, as yet, just a possibility