key: cord-0949477-3dp1gjl5 authors: Chu, Haoran; Liu, Sixiao title: Integrating health behavior theories to predict American’s intention to receive a COVID-19 vaccine date: 2021-02-17 journal: Patient Educ Couns DOI: 10.1016/j.pec.2021.02.031 sha: 5a74021a3dbce95ea49dddeb201ef3ae3aeb079c doc_id: 949477 cord_uid: 3dp1gjl5 OBJECTIVE: Integrating constructs from three prominent health behavior theories including the extended parallel process model, the health belief model, and the theory of planned behavior, this study seeks to identify sociopsychological factors that influenced American’s intention to receive a COVID-19 vaccine. METHOD: An online survey was delivered to a U.S. sample (N = 934), assessing the influences of risk perception and fear associated with COVID-19, beliefs about and attitudes toward COVID-19 vaccines, self-efficacy, social and psychological contexts, and demographic characteristics on people’s intention to get COVID-19 vaccines. RESULTS: Most respondents intended to get vaccinated. However, they tended to underestimate their risks of contracting COVID-19. Disease exposure led to higher uptake intent via the mediation of fear. Safety concerns negatively influenced vaccination intention, while perceived community benefits were positively associated with vaccination intention. Positive attitudes toward vaccines and recent vaccine history were positively linked to vaccination intent. CONCLUSION: This study attests the effectiveness of HBT constructs in predicting people’s intention to receive a COVID-19 vaccine. PRACTICE IMPLICATIONS: The results point to the importance of fostering confidence in vaccine safety and countering overoptimism of individual susceptibility to the disease in interventions promoting COVID-19 vaccines uptake. The coronavirus disease-2019 (COVID-19) pandemic has caused catastrophic damages worldwide [1] . As of early 2021, more than 80 million cases of infections and 2 million deaths have been reported worldwide [1] . However, as effective treatment of the disease remains unavailable, societies are relying on preventive measures to curb the pandemic [2, 3] . One of the J o u r n a l P r e -p r o o f most effective preventive measures to contain the spread of infectious diseases is vaccine [4] . protect those unable to get vaccines through "herd immunity" [5] . However, despite its effectiveness in preventing infectious diseases, vaccine hesitancy is on the rise globally, leading to the re-emergence of VPDs such as measles [6, 7] . Though public health institutions worldwide have been disseminating vaccines to control the pandemic, polls show that many were reluctant to get vaccinated [8] . To develop effective interventions that promote acceptance of COVID-19 vaccines, it is critical to identify factors that influence people's intention to get vaccinated. Decades of research in health psychology have generated multiple health behavior theories (HBT) that identify sociopsychological factors influencing individual's health behavior [9] . Studies on vaccines uptake ranging from childhood vaccines [10] to HPV vaccines [11] also benefited tremendously from HBTs, such as in predicting parents' intention to vaccinate their children for VPDs [10] and individuals' intention to vaccinate themselves against HPV infection [11] . Notably, most HBTs focus on several similar sets of factors that predict the initiation and maintenance of health behaviors [9, 12] . Correspondingly, researchers have rallied for the comparative examination, refinement, and integrations of different HBTs [9, 11, 12] . In the meantime, the novel challenges brought about by the COVID-19 pandemic also necessitate a comprehensive investigation of factors that predict people's intention to get the COVID-19 vaccines. On the one hand, it aids the strategic design of vaccine promotion campaigns addressing factors that reduce voluntary vaccination. On the other, knowing who are more likely to receive a vaccine helps authorities plan the distribution of COVID-19 vaccines. To address such goals, this study examines five sets of HBT constructs and seeks to identify their influences on people's intention to receive a COVID-19 vaccine. Based on three prominent HBTs including the health belief model (HBM) [13] , the theory of planned behavior (TPB) [14] , and extended parallel process model (EPPM) [15] , we focus on factors including risk perception and fear associated with COVID-19, attitudes and beliefs related to COVID-19 vaccines, selfefficacy, social and psychological contexts, and demographics ( Figure 1) . Notably, as COVID-19 vaccines were not widely available in the United States when this study was conducted, we focus on the intention to get COVID-19 vaccines due to its strong association with the actual uptake behavior [11, 14] . Vaccination, like many health behaviors, is adopted to prevent negative health consequences such as suffering from VPDs [16] . It is thus arguable that the extent to which people believe a VPD is severe and likely to affect them should predict their intention to get vaccinated [12] . HBM and EPPM measures people's perception of health risks with similar constructs, including perceived severity of and perceived susceptibility to health threats [9] . In addition to risk perception, HBTs also suggest that affective response to health risks motivate actions to overcome their adverse effects [15, 17] . Fear as a negative emotion was particularly relevant to behavioral change [18] . For instance, research shows that increased fear from reading a narrative message motivated female research participants to receive an HPV vaccine [18] . It is worth noting that too much fear could also prevent action as people may just disregard the threats to avoid feeling overwhelmed [15] . In the context of COVID-19 vaccination, the large number of infections and casualties may have led to heightened risk perception and strong fear [19] . However, the prolonged pandemic and the lower mortality rates among younger J o u r n a l P r e -p r o o f populations may also lead to fatigue of practicing preventive measures and overoptimism of one's susceptibility to the disease. As a consequence, some may hesitate to get a COVID-19 vaccine due to lower risk perception and fear. In addition to risk perception and fear, HBTs argue that attitudes toward and beliefs about the health behaviors also shape people's intention to adopt them [9, 11] . They are often operationalized as perceived benefits and barriers in HBM, response efficacy in EPPM, and positive or negative behavioral beliefs in TPB [9] . These factors can be categorized into two subgroups, respectively capturing the benefits and barriers associated with the health behaviors. In vaccine research, perceived benefits of vaccines (e.g., reduced disease threat) were found to be strong predictors of vaccination intention, while perceived cost or barriers (e.g., monetary cost, effort exertion) of getting vaccinated were negatively associated with uptake intent (e.g., influenza vaccine [20] , HPV vaccines [21] , Zika Vaccine [22] ). In the context of COVID-19 vaccines, we focus on five interrelated attitudes and beliefs associated with the vaccines, including perceived benefits of getting COVID-19 vaccines for self and communities, perceived barriers of getting COVID-19 vaccines, and attitudes toward to getting COVID-19 vaccines. Notably, perceived benefits and barriers are conceptually similar to positive and negative behavioral beliefs specified in TPB [12] . Such beliefs, according to TPB, shape people's attitudes toward the behavior, which subsequently influence behavioral intent [9] . Knowing that health behaviors such as getting vaccinated prevent negative consequences may not be enough to motivate behavioral adoption [9, 12] . HBTs argue that feeling capable of J o u r n a l P r e -p r o o f executing such behaviors are also key to behavioral change [23, 24] . Such perceived capability is conceptualized as perceived behavioral control in TPB and self-efficacy in EPPM [9] . Recent TPB studies often operationalize perceived behavioral control as self-efficacy due to their similarities [9, 25] . Research also shows that self-efficacy is positively related to vaccines uptake [26, 27] . We extract three sets of contextual factors from HBTs and vaccine research, including subjective norms (TPB [28] ), cues to action (HBM [11] ), and baseline vaccine hesitancy [6] . Subjective norms include injunctive norms, which are approvals of health behaviors by people important to the health decision-maker, and descriptive norms, which denote important others' behaviors [29] . TPB research shows that both perceived descriptive and injunctive norms are positively related to vaccines uptake [30, 31] . Cues to action specifies motives and hints of actions embedded in one's surrounding environment such as doctor's recommendations [11] . Research also shows that disease exposure or knowledge of VPDs are positive predictors of vaccines uptake [27] . In the COVID-19 context, it is possible that exposure to COVID-19 cases such having family or friends tested positive for COVID-19 may function as a behavioral cue [6] . Further, serving as an essential worker during the COVID-19 lockdowns may also be a cue to action. On the one hand, essential workers may be more susceptible to the disease due to the risk of exposure, while on the other, public health officials have called for earlier vaccination for this group [2, 3] . The last set of contextual factors include baseline vaccine hesitancy, which describes the attitudes and behaviors surrounding people's decision to delay and refuse vaccination [6] . Vaccine hesitancy is often operationalized as attitudes toward vaccines or past vaccination behavior [6, 7] . Research shows that positive attitudes toward vaccines in general are positively associated with people's intent to get specific vaccines [6, 32] , and individuals who have received vaccines recently are more likely to get other vaccines [33] . In addition to their direct effects, risk perception, fear, self-efficacy, and beliefs about COVID-19 vaccines may also mediate contextual factors' influence on vaccination intention. First, social cognitive theory suggests that people learn not only by directly interacting with the environment, but also by vicariously observing other's actions [34] . Therefore, socially important others' beliefs and behaviors may influence people's evaluation of the vaccine and their confidence in getting vaccinated [11, 35] . In terms of COVID-19 vaccines, it is likely that subjective norms may influence self-efficacy, which would subsequently influence uptake intent. Second, people's perception of the vaccines may also be influenced by their existing attitudes toward other vaccines [6, 7] . Thus, attitudes toward COVID-19 vaccines may mediate baseline vaccine-hesitancy's influences on intention to receive a COVID-19 vaccine. Third, as exposure to COVID-19 cases and serving as essential workers may lead to higher contraction risk and elevated risk perception, severity and susceptibility perception may also mediate its impacts on uptake intent. Lastly, recent vaccination history may boost self-efficacy which would lead to increased uptake intent, as successful past experiences are often positively related to self-efficacy [34] . Lastly, demographic factors are also associated with vaccines uptake intent. Due to historical and cultural reasons, minorities in the United States are often reluctant to receive novel medical treatment [36, 37] . Gender difference in vaccination behavior was also observed in some studies, but the patterns of such difference vary across contexts [38] . Older adults and individuals with higher education and income often show higher vaccination intention [39] [40] [41] . J o u r n a l P r e -p r o o f To address the challenges of the COVID-19 pandemic and aid the strategic promotion and distribution of COVID-19 vaccines, we utilize three HBTs to identify sociopsychological factors that influence American's intention to receive a COVID-19 vaccine. Based on HBM and EPPM, we hypothesize that perceived susceptibility to and severity of COVID-19 and fear will be positively associated with people's intention to get a COVID-19 vaccine (H1). According to TPB and EPPM, we hypothesize that self-efficacy is positively related to vaccination intention (H2). Synthesizing HBM, EPPM, and TPB, we ask three research questions. First, are perceived benefits and barriers of COVID-19 vaccination associated with uptake intent directly or indirectly via the mediation of attitudes toward COVID-19 vaccines (RQ1)? Second, are contextual factors (i.e., subjective norms, cues to action, and vaccine hesitancy) directly and indirectly associated with people's intention to receive a COVID-19 vaccine (RQ2)? Lastly, how are demographic characteristics associated with vaccination intention (RQ3)? Upon IRB approval at the lead author's institution, data collection was completed during early September 2020. A sample of participants with demographics similar to the United States population was recruited on Prolific.co. 1,043 Individuals opened the survey, and 1,027 continued with informed consent. Among them, 1001 participants completed the survey and were rewarded 2.00 U.S. dollars. Response from 54 participants who failed one or two attention check questions were removed. Responses from 13 participants who indicated that they were tested positive for COVID-19 and/or COVID-19 antibody were dropped, resulting in a final sample of 934 participants. J o u r n a l P r e -p r o o f HBT and vaccine research constructs including perceived severity of and susceptibility to COVID-19, fear of COVID-19 [18, 27] , perceived individual benefits of COVID-19 vaccines [11, 42] , perceived community benefits of COVID-19 vaccines, perceived barriers to getting COVID-19 vaccines including safety concerns and cost concerns [21] , subjective norms, baseline vaccine hesitancy including attitudes toward vaccines in general and recent vaccination history, cues to actions, and demographics were measured in the survey. Measurement items, reliability indices, means, and standard deviations of the measurement instruments are presented in Table 1 . Scales were adopted from existing research if available. Q-Q plot was generated in R to assess multivariate normality of the measurement items [43] . Upon inspection, the data failed to achieve multivariate normality. To account for nonnormality, all measurement and path models were analyzed with maximum likelihood estimation with robust standard errors [44] . Indirect effect models were estimated with maximum likelihood estimation with bootstrapped sub-samples (N = 5,000). We first inspected the measurement model [45] . The model has achieved satisfactory fit Path coefficient estimates are reported in Figure 2 and Table 2 The average age of participants was 46.01 years (SD = 16.17). The majority of participants identified as female (n = 468, 50.1%), followed by male (n = 455, 48.7%) and other gender (n = 11, 1.2%). Approximately three quarters of participants identified as non-Hispanic White or Caucasian (n = 698, 74.7%), followed by Black or African American (n = 114, 12.2%), Hispanic or Latino (n = 34, 3.6%), Asian, Pacific Islander or Native American (n = 68, 7.3%), and other racial groups (n = 20, 2.1%). The median education level was 4-year college degree, and the median household income was between US$ 50,000 and 74,999. RQ3 asks about demographic factors' association with COVID-19 vaccines uptake intent. No significant effect of the demographic variables was identified after controlling for the HBT constructs. In general, participants perceived COVID-19 as a severe health risk. However, mean perceived susceptibility was significantly lower than perceived severity (paired-sample t(933) = 28.70, p < .001). The average rating for fear was below the scale mid-point, suggesting that participants were not very fearful of the disease. H1 was partially supported as only fear was positively associated with intention to receive a COVID-19 vaccine. However, perceived J o u r n a l P r e -p r o o f susceptibility's association with vaccination intention was approaching statistical significance (B = 0.114, SE = 0.062, p = 0.064). Participants showed positive attitudes toward COVID-19 vaccines. They also perceived COVID-19 vaccines as beneficial to both themselves and their communities. Participants reported that concerns about vaccine safety were more likely to prevent vaccination than concerns about cost (paired-sample t(933) = 28.36, p < .001). In response to RQ1, we found that perceived community benefits of and positive attitudes toward COVID-19 vaccines were positively associated with intention to get the vaccines. However, stronger safety concerns were related to lower vaccination intention. In addition to their direct effects, beliefs about COVID-19 vaccines' benefits and barriers also indirectly influenced intention to receive a COVID-19 vaccine (RQ1b). Attitudes toward COVID-19 vaccines mediated perceived community benefits and safety concerns' association with uptake intent, but the former was positive while the latter was negative. Interestingly, attitudes toward COVID-19 vaccines also mediated cost concerns' positive relationship with vaccines uptake. Our respondents generally believed that they will be able to get COVID-19 vaccines to prevent contracting COVID-19. Different from existing research findings, no significant relationship was identified between self-efficacy and intention to get vaccinated for COVID-19, rejecting H2. J o u r n a l P r e -p r o o f More than half of our sample had some experiences with COVID-19. Particularly, more than one third of participants knew someone who was tested positive for COVID-19 and more than 20% of participants reported having family or close friends tested positive for COVID-19. Further, more than one hundred respondents indicated that someone they knew died due to COVID-19, again showing the dire situation of the pandemic. About 20% of our respondents indicated that they worked as an essential worker during COVID-19 lockdowns. As for subjective norms, participants in general believed people similar to them or important to them would get a COVID-19 vaccine (i.e., descriptive norms) and would want them to get vaccinated against COVID-19 (i.e., injunctive norms). In terms of baseline vaccine hesitancy, our participants largely thought of vaccines positively and more than half of them reported that they had received at least one vaccine in the past 18 months prior to completing the survey. In response to RQ2, we found that having positive baseline attitudes toward vaccines in general and received some vaccines recently were positive predictors of intention to receive a COVID-19 vaccine. Further, descriptive norms were also positively associated with vaccination intentions. Though exposure to COVID-19 cases was not directly linked to uptake intent, fear mediated its positive relationship with vaccination intention. Additionally, the relationship between attitudes to vaccines in general and intention to receive a COVID-19 vaccine was mediated by perceived benefits and attitudes toward COVID-19 vaccines specifically. The current study integrates factors from three prominent HBTs including EPPM, HBM, and TPB to investigate sociopsychological factors associated with American's intentions to get COVID-19 vaccines. In general, participants indicated that they were likely to get vaccinated for COVID-19 once the vaccines are available. This finding is encouraging as massive vaccination is J o u r n a l P r e -p r o o f key to controlling the spread of COVID-19 [3] . However, approximately 20% of participants reported some extent of unwillingness to get the vaccines (average uptake intent score below the scale mid-point). Considering that herd immunity against VPDs sometimes require an immunization rate of 70% to 90% and the immunity against COVID-19 developed by vaccination may not last as long as immunity for other diseases [2] , efforts are needed to design and implement interventions that effectively promote vaccination, especially among populations reluctant to get the vaccines. Participants in general perceived COVID-19 as a severe health risk. However, they tend not to feel very vulnerable to and afraid of the disease. Such findings show that people were generally optimistic about their own risks of suffering from COVID-19, which is consistent with the optimistic bias observed in earlier research [3, 19] . There are two possible explanations for the finding that fear was positively associated with intention to receive a vaccine. First, fear as emotional response may arise from cognitive appraisals of COVID-19 and served as a more immediate predictor of vaccination intention than susceptibility perception [47] . Second, we may fail to capture any effect of severity perception due to its limited variance (i.e., ceiling effect). In summary, the general public may have recognized the severity of COVID-19, but the underestimation of their risks of contracting and suffering from the disease may prevent them from getting vaccinated. Campaigns to promote COVID-19 vaccines should consider highlighting personal risks to the disease and using fear appeal messages when communicating to populations that are less susceptible to COVID-19 (e.g., younger population). Our findings indicate that Americans held a generally positive view toward COVID-19 vaccines. They considered the vaccines as beneficial to both themselves and their communities. However, the accelerated development of the vaccines, especially in comparison to earlier vaccines, may have led to heightened safety concerns [3] . Cost concerns, on the other hand, was not a serious barrier to people's vaccination intentions. More importantly, we found that perceived community benefit of COVID-19 vaccines was positively associated with vaccination intention both directly and indirectly through the mediation of attitudes toward the COVID-19 vaccines. Differently, concerns about the safety of COVID-19 vaccines were negatively associated with uptake intent, directly and indirectly through the mediation of attitudes toward the COVID-19 vaccines. Therefore, public health campaigns aiming at increasing the vaccination rate should address the community benefits of COVID-19 vaccines, while also maintain high level of transparency regarding the vaccines' safety and effectiveness. Notably, we also found that cost concerns were positively associated with intention to get vaccinated for COVID-19, and the relationship was mediated by attitudes toward the COVID-19 vaccines. Such pattern is consistent with earlier finding where practical concerns were positively linked to behavioral intention [21] . Therefore, providing the vaccines at a reasonable cost or for free may help increase vaccination rates, especially among people who intend to get vaccinated. We found that participants were confident in their ability to get the COVID-19 vaccines. However, self-efficacy was not significantly associated with vaccination intention. The absence of a significant relationship may be attributable to the fact that vaccines were still not available. As the transtheoretical model (TTM) of behavioral change suggests, difference in self-efficacy tend to develop at later stages of people's health decision-making [48] . Limited variance in self-efficacy J o u r n a l P r e -p r o o f may thus prevent us from identifying its relationship with vaccination intention. Notably, injunctive and descriptive norms were differently associated with self-efficacy. Believing that important others will get the vaccines (i.e., descriptive norms) was positively related to selfefficacy, whereas the relationships was negative between beliefs that important others would want oneself to get vaccinated (i.e., injunctive norms) and self-efficacy. Such difference may emerge as people learn from others' behaviors [34] , but too much preaching may also lead to psychological reactance. Our findings confirm the widespread of COVID-19 cases and mortalities reported elsewhere [1, 19] . First-hand experience with the disease was related to heightened fear and increased intention to get vaccinated. Such finding may indicate that exposure to COVID-19 countered the negative influences of overoptimism on vaccination intention. Therefore, campaigns encouraging vaccination against COVID-19 may stress the personal relevance of COVID-19 as a means to overcome overoptimism and stipulate vaccination intention. It is also encouraging to see that most participants held positive views toward vaccines and considered getting COVID-19 vaccines a socially sanctioned behavior. Baseline attitudes toward vaccines and the vaccinefriendly norms were also conducive to vaccination intention. Therefore, promotion of COVID-19 vaccines should be considered as an integral part of the long-term efforts to reduce vaccine hesitancy [6] . It is necessary to not only foster acceptance of the COVID-19 vaccines, but also cultivate an enduring trust in vaccines and other health measures. This study also has some limitations. First, the online sample may limit the generalizability of our findings. Future research should consider recruiting a more diverse sample and re-examine the relationships reported here. Second, as the COVID-19 vaccines were yet to be widely available when this study was conducted, actual vaccines uptake was not measured. Though behavioral intention and actual behaviors tend to correlate highly [14] , we recommend future research to test the current framework at later stage of the pandemic or with other vaccines and health behaviors. Integrating findings from prominent HBTs, this study offers a timely overview of sociopsychological factors that are related to American's intention to get vaccinated for COVID- 19 . We found that despite recognizing the severity of the disease, people felt less susceptible to and afraid of its negative consequences. Such overoptimism may prevent wide acceptance of COVID-19 vaccines. Further, safety concerns are negatively associated with vaccination intention. Lastly, public acceptance of COVID-19 vaccines was largely influenced by their perceptions of vaccines in general, which confirms the importance of sustained efforts in cultivating vaccine acceptance. Findings from the current study has several implications for health campaigns and Note. a Dummy-coded variable (1 = knowing someone who was tested positive for or died due to COVID-19, 0 = not having such experience); b dummy-coded variable (1 = served as an essential worker during COVID-19 lockdowns; 0 = did not serve as an essential worker during COVID-19 lockdowns); c dummy-coded variable (1 = received vaccines in the past 18 months, 0 = did not receive vaccine in the past 18 months or not sure); d dummy-coded variable with male as reference group; e dummy-coded variable with non-Hispanic White or Caucasian as reference group; * p < .05; ** p < .01; *** p < .001. 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