key: cord-0945823-sz1depzi
authors: Yuriditsky, Eugene; Mitchell, Oscar J.L.; Brosnahan, Shari B.; Smilowitz, Nathaniel R.; Drus, Karsten W.; Gonzales, Anelly M.; Xia, Yuhe; Parnia, Sam; Horowitz, James M.
title: Clinical characteristics and outcomes of in-hospital cardiac arrest among patients with and without COVID-19
date: 2020-11-21
journal: Resuscitation plus
DOI: 10.1016/j.resplu.2020.100054
sha: 297175f3b503d16d532f70943003dab3a7c93ad3
doc_id: 945823
cord_uid: sz1depzi

Aims To define outcomes of patients with COVID-19 compared to patients without COVID-19 suffering in-hospital cardiac arrest (IHCA). Materials and methods We performed a single-center retrospective study of IHCA cases. Patients with COVID-19 were compared to consecutive patients without COVID-19 from the prior year. Return of spontaneous circulation (ROSC), 30-day survival, and cerebral performance category (CPC) at 30-days were assessed. Results Fifty-five patients with COVID-19 suffering IHCA were identified and compared to 55 consecutive IHCA patients in 2019. The COVID-19 cohort was more likely to require vasoactive agents (67.3% v 32.7%, p = 0.001), invasive mechanical ventilation (76.4% v 23.6%, p < 0.001), renal replacement therapy (18.2% v 3.6%, p = 0.029) and intensive care unit care (83.6% v 50.9%, p = 0.001) prior to IHCA. Patients with COVID-19 had shorter CPR duration (10 min v 22 min, p = 0.002). ROSC (38.2% v 49.1%, p = 0.336) and 30-day survival (20% v 32.7%, p = 0.194) did not differ. A 30-day cerebral performance category of 1 or 2 was more common among non-COVID patients (27.3% v 9.1%, p = 0.048). Conclusions Return of spontaneous circulation and 30-day survival were similar between IHCA patients with and without COVID-19. Compared to previously published data, we report greater ROSC and 30-day survival after IHCA in COVID-19.

Whether the initially-described poor outcomes were related to the 44 disease process, degree of critical illness, or a function of provider and 45 institutional approaches to COVID-19 patients with IHCA is unknown. 46 We hypothesized that outcomes among COVID-19 patients with IHCA would be comparable to IHCA outcomes among non-COVID- was not offered at our institution during this timeframe. The median duration of CPR was significantly shorter among 

Coronavirus Disease