key: cord-0939337-dajax0hl
authors: Paolino, Giovanni; Di Nicola, Matteo Riccardo; Cantisani, Carmen; Mercuri, Santo Raffaele
title: Pityriasis rosea infection in a COVID‐19 patient successfully treated with systemic steroid and antihistamine via telemedicine: Literature update of a possible prodromal symptom of an underlying SARS‐CoV‐2 infection
date: 2021-05-24
journal: Dermatol Ther
DOI: 10.1111/dth.14972
sha: c8ca6ec706bef25da45121ab40084cadedd5762e
doc_id: 939337
cord_uid: dajax0hl

nan

and HHV-7 (probable etiological agents of PR) can be reactivated by viruses of the coronavirus family, including SARS-CoV-2. 4, 6 A 33-year-old healthy Caucasian woman, with a personal history proving negative for any recent drug intake and a type III Fitzpatrick's phototype, presented, via a telemedicine consultation, with a 20-dayold history of a cutaneous manifestation characterized by the onset of an erythematous, scaly and annular "herald patch" on her right breast.

Three days later, generalized papular and plaque-type lesions erupted across the trunk with a "Christmas tree" like pattern, sparing the face and distal extremities. On the fifth day, after the initial onset of the cutaneous manifestation, the patient reported fatigue and developed a fever and a cough. The cutaneous lesions had shown a marked erythematous appearance with superficial desquamation associated with pruritus ( Figure 1A F I G U R E 1 A, Onset of the cutaneous symptoms with a "herald patch," erythematous and scaly annular patch on the right breast. Five days later, generalized papular and plaque-type lesions occurred all over the trunk, with a "Christmas tree" like pattern, while the face and the distal part of the limbs were spared. Insert: simultaneously with increasing cutaneous lesions the patient developed fever, fatigue, and cough (SARS-CoV-2 positive). The individual skin lesions assumed a more erythematous and purpuric appearance with a fine central desquamation. Most likely these features were associated with the general inflammatory induced by SARS-CoV-2 infection. B, Systemic steroid treatment, systemic antihistamine, and a moisturizing cream accelerated the healing process of the cutaneous lesions. The systemic symptoms associated with SARS-CoV-2 (fever, fatigue, and cough) also healed after only 3 days

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