key: cord-0932911-zi68q03a authors: Wu, Yan-Ting; Li, Cheng; Zhang, Chen-Jie; Huang, He-Feng title: Is termination of early pregnancy indicated in women with COVID-19? date: 2020-05-20 journal: Eur J Obstet Gynecol Reprod Biol DOI: 10.1016/j.ejogrb.2020.05.037 sha: 7d78d2e846f7db610daca760684c5ffd5e1e1ac8 doc_id: 932911 cord_uid: zi68q03a nan Yan-Ting Wu, M.D. 1 Therefore, consideration of termination of pregnancy has to be individualized during this COVID-19 outbreak. For pregnant patients with mild symptoms, treatment should be modified to avoid using teratogenic drugs near the fetus. Patients are commonly at higher oxygen demand during early pregnancy, so hypoxemia should be monitored, and interventions should be provided without delay. For severe patients during early pregnancy, the first priority is to ensure maternal safety. Decisions of early pregnancy termination should be considered upon risk factors including viral load, transmission generations, range of lung lesions by CT (more than two lobes), maternal age, and coexisting disorders (diabetes, cardiovascular diseases etc.). The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. No conflict of interest. He-feng Huang put forward the initial ideas and opinions, which were drafted by Yanting Wu, Cheng Li, and Chen-jie Zhang. Ethics approval Not applicable. Not applicable. Coronavirus disease 2019 among pregnant Chinese women: Case series data on the safety of vaginal birth and breastfeeding Clinical characteristics and intrauterine vertical transmission potential of COVID-19 infection in nine pregnant women: a retrospective review of medical records Pregnancy and perinatal outcomes of women with severe acute respiratory syndrome Impact of Middle East respiratory syndrome coronavirus (MERS-CoV) on pregnancy and perinatal outcome A Novel Coronavirus Emerging in China -Key Questions for Impact Assessment Thanks to everyone involved in the fight against the epidemic.