key: cord-0923559-t9ir627s authors: Goldust, M; Abdelmaksoud, A; Navarini, AA title: Hand disinfection in the combat against Covid‐19 date: 2020-05-03 journal: J Eur Acad Dermatol Venereol DOI: 10.1111/jdv.16574 sha: 34797737dc90f8092c87344bee3ee993eb45e9a7 doc_id: 923559 cord_uid: t9ir627s The World Health Organization (WHO) has declared a global health emergency over a new coronavirus. The new corona virus (SARS‐CoV‐2) has raised global attention with raising concerns of rapid spread from human‐to‐human. Like severe acute respiratory syndrome (SARS)‐nCoV, 2019‐nCoV can be passed directly from person to person by respiratory droplets, and may also be transmitted through contact and fomites. This article is protected by copyright. All rights reserved The World Health Organization (WHO) has declared a global health emergency over a new coronavirus. The new corona virus (SARS-CoV-2) has raised global attention with raising concerns of rapid spread from human-to-human. Like severe acute respiratory syndrome (SARS)-nCoV, 2019-nCoV can be passed directly from person to person by respiratory droplets, and may also be transmitted through contact and fomites. 1 Currently, there is no vaccine or specific therapeutic option against the new virus. Hygienic hand antisepsis is one of the most important measures in preventing healthcare-and outbreak-associated viral infections. Hence, there is an emergency in identifying efficacious antiviral agents to combat the disease. 2 Appropriate measures to decrease the risk of transmission from infected person to the patients, visitors and health care workers include hand hygiene. Appropriate care is to be considered for higher risk patients with chronic lung disease, diabetes, and renal failure, as well as immunocompromised patients. WHO formulations I and II (two alcohol-based hand rubs) or povidone iodine (PVP-I) are highly effective against the enveloped corona viruses (Table 1) , as well as other antiseptic agents. 3 If alcohol-based hand rubs (gel or foam) or povidone iodine are This article is protected by copyright. All rights reserved not available, ethanol 70% solution may be used. These are all available as commercial solutionshowever, the correct use is crucial and has received insufficient investigation. The accessibility of the WHO / PVP-I formulations as well as their correct use is therefore likely to be of significant benefit for human health on a global scale, particularly in the developing countries. 3 Repeated hand disinfection must be paired with simple handwashing. This has been shown to be of even increased efficiency compared to disinfection for both enveloped and nonenveloped viruses. 8 Ultraviolet germicidal irradiation (UVGI) is a disinfection method that uses UVC radiation to Phenolic -Bacteria. -Enveloped viruses. -Non-enveloped viruses "variable" Chlorine -Bacteria Pathogenicity and Transmissibility of 2019-nCoV-A Quick Overview and Comparison with Other Emerging Viruses. Microbes Infect Epidemiological and clinical characteristics of 99 cases of 2019 novel coronavirus pneumonia in Wuhan, China: a descriptive study Efficacy of various disinfectants against SARS coronavirus Simplifying the WHO 'how to hand rub' technique: three steps are as effective as six-results from an experimental randomized crossover trial Effect of hand lotion on the effectiveness of hygienic hand antisepsis: Implications for practicing hand hygiene Prevalence and risk factors of hand eczema in hospital-based nurses in northern China Infection control and MERS-CoV in health-care workers Handwashing and Ebola virus disease outbreaks: A randomized comparison of soap, hand sanitizer, and 0.05% chlorine solutions on the inactivation and removal of model organisms Phi6 and E. coli from hands and persistence in rinse water Efficacy of an Automated Multiple Emitter WholeRoom Ultraviolet-C Disinfection System Against Coronaviruses MHV and MERS-CoV Amotosalen photochemical inactivation of severe acute respiratory syndrome coronavirus in human platelet concentrates This article is protected by copyright. All rights reserved -Non-enveloped viruses