key: cord-0919609-cjyputwx
authors: Li, Xiaohu; Zeng, Xiaosong; Liu, Bin; Yu, Yongqiang
title: COVID-19 Infection Presenting with CT Halo Sign
date: 2020-02-12
journal: Radiol Cardiothorac Imaging
DOI: 10.1148/ryct.2020200026
sha: 34cd0e49a7309f37effde3a12f84311a32e6ac47
doc_id: 919609
cord_uid: cjyputwx

nan

presented to the hospital with a 4-day history of fever and cough. At admission, her body temperature was elevated to 38.5°C (101.3°F) and coarse breath sounds were heard during auscultation. Laboratory studies showed leucopenia, and positive sputum analysis using real-time reverse transcriptase fluorescence polymerase chain reaction confirmed infection by COVID-19 (formerly known as 2019 novel coronavirus [2019-nCoV]) (1,2). Noncontrast chest CTs obtained at admission and after 4 days of hospitalization (Figure) showed a right upper lobe nodule with ground-glass halo, which increased in size between studies, concurrently with the deterioration of clinical symptoms.

A recent case series (3) identified involvement of multiple lobes and predominance of ground-glass opacities as radiologic hallmarks of the outbreak of CO-VID-19 pneumonia on CT. The CT halo sign has been classically described in hemorrhagic nodules, typically seen in angioinvasive fungal infections, hypervascular metastases, and vasculitides; however, viral infections and organizing pneumonia are known differential causes for the halo sign (4) . The present case highlights CT pattern that can be found within the spectrum of radiologic presentations of COVID-19 pneumonia.

Disclosures of Conflicts of Interest: X.L. disclosed no relevant relationships. X.Z. disclosed no relevant relationships. B.L. disclosed no relevant relationships. Y.Y. disclosed no relevant relationships.

A Novel Coronavirus from Patients with Pneumonia in China

Clinical features of patients infected with 2019 novel coronavirus in Wuhan, China

CT Imaging of the 2019 Novel Coronavirus (2019-nCoV) Pneumonia. Radiology 2020

The CT halo sign

To order printed copies, contact reprints@rsna.org COVID-19 Infection Presenting with CT Halo Sign Xiaohu Li, MD • Xiaosong Zeng

Y.) and the Department of Radiology