key: cord-0915126-w798b8mn authors: de Albuquerque, Thaís Rodrigues; Macedo, Luis Fernando Reis; de Oliveira, Erika Galvão; Neto, Modesto Leite Rolim; de Menezes, Irwin Rose Alencar title: Vaccination for COVID-19 in children: Denialism or misinformation? date: 2022-02-08 journal: J Pediatr Nurs DOI: 10.1016/j.pedn.2022.01.015 sha: 7a6be41c12fdf45265cb7bee1917eadac4855e75 doc_id: 915126 cord_uid: w798b8mn In the current pandemic scenario, vaccines for children have been scientifically approved; however, there is a challenge faced globally: parents' hesitation about vaccinating their children for COVID-19, which can hamper adherence to vaccine campaigns. This issue is due to the lack of information or access to fake news that affects the parents' power of judgment. The experience of the vaccine process with Pfizer's immunizer in several countries successfully reduced the number of hospitalized and prevented hundreds of child deaths from COVID-19. All health professionals must encourage the vaccination of children from the age of 5, sharing reliable scientific data, thus reducing the spread of fake news. not vaccinated, the alarming number of deaths confirmed by the virus, and the emergence of variants with a high degree of infectivity, the government of Brazil says that "there is no death of children that justifies emergency vaccination" neglecting the need for vaccination of children (Weterman, 2021) and in opposition to evidence demonstrated by other countries. Epidemiological data show that most children had mild or no clinical symptoms; however, with the emergence of new variants, thousands are being hospitalized; it is observed that there are several deaths due to COVID-19, demonstrating that this age group is equally essential for immunization. In addition, there are children with underlying conditions, such as immunosuppressed individuals and those with comorbidities, who are more likely to suffer diseases and complications from the disease. In addition, the long period of social isolation has made it impossible to practice sports and exercise, which can have repercussions on children's cardiovascular and hormonal systems, making them aware of infectious diseases such as COVID-19 (Thompson & Rasmussen, 2021) .Epidemiological studies from the Houston hospital in the USA anteriorly reported that in January, the number of hospitalizations of children with COVID-19 quadrupled with the expansion of infections caused by the Ômicron and Delta variants during the end-ofyear festivities, supering the rates found in August 2021, during the wave of the Delta variant (Yan & Caldwell, 2021) . Complications of COVID-19 in children are usually associated with a rare post-infectious syndrome, the Multisystem Inflammatory Syndrome or Pediatric Multisystem Inflammatory Syndrome -Temporarily Associated with SARS-CoV-2, which exclusively affects children and leads to the hospitalization in most cases (Radia et al., 2021) . Vaccines, until recently, were only available for the adult population, but recently the immunizing of Pfizer-BioNTech (COMIRNATY) was authorized for children from the age of 12 by U.S. Food and Drug Administration (FDA) due to its expressive results in reducing the death and hospitalization in the children with COVID -19 (Thompson & Rasmussen, 2021) . In its clinical studies, this manufacturer also demonstrated effectiveness and safety in children aged 5 to 11 years, thus obtaining approval in December 2021 for immunization of this population, which represents a significant achievement for the pediatric population (Walter et al., 2022) .Scientific advances and clinical research have shown society that with an investment in science, with severe and rigorous studies, it is possible to quickly and effectively solve pandemic situations. However, in Brasil, the cut of scientific investments, the skepticism, denialism, and propagation of false information, often by members of a scientific society, based on preliminary or questionable scientific studies, raised and casts doubt on the credibility of the immunization process, mainly aimed at children. The challenge now is the hesitation of the vaccine by parents and guardians of children. This phenomenon is related to the lack of information or widespread access to fake news content, highly propagated during the pandemic. The fear of adverse reactions to the vaccine is also pointed out as a preponderant factor for family members to refuse to vaccinate their children; however, like adults, children are susceptible to mild symptoms that can be correlated as a reflect an excellent sign that the immune system is building up protection against this disease (Chaudhary et al., 2021; Thompson & Rasmussen, 2021) . On the other hand, the movement of the anti-vaccination of the skeptical public, if contrapose the undeniable veracity observed that the immunizations present high efficacy, which confirms the drastic reduction in the number of hospitalizations and deaths due to the immunization process for all public. Hesitation to vaccinate leads to a lack of adherence to the vaccination campaign and is directly related to misinformation that can delay the end of the pandemic and give the virus a chance to find more effective ways to infect more people, including children. We understand that negative experiences in childhood can reflect negative outcomes in adult life; therefore, although the levels of infant mortality from COVID-19 are not extraordinary, they must be protected from emotional suffering as a result of social distancing, hospitalization, and parental separation.Brazil is world-renowned for its successful history in immunization, eradicating many diseases that plagued children, such as measles and polio. In this way, vaccination of children against SARS-CoV-2 is urgent and essential to achieving the necessary immunity in the fight against the current global pandemic. Because of the above, we affirm that the attitudes of organized civil society, scientific entities, and the various actors in campaigns that call for and encourage the vaccination of children from 5 years of age to be welcomed and positive. However, it is necessary to share reliable scientific data create advertising campaigns to combat false information that is multiplied, aiming at the end of the transmission chain of COVID-19 and beyond, the well-being and health of the entire population worldwide. Regional University of Cariri, Crato, Brazil. The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest. Impact of the Delta variant on vaccine efficacy and response strategies Coronavirus disease 2019 vaccine impact on rates of severe acute respiratory syndrome coronavirus 2 cases and postvaccination strain sequences among health care workers at an urban academic medical center: A prospective cohort study Factors influencing COVID-19 vaccine hesitancy and acceptance among the Pakistani population COVID-19 vaccine hesitancy: A survey in a population highly compliant to common vaccinations Government responses and COVID-19 deaths: Global evidence across multiple pandemic waves Multi-system inflammatory syndrome in children & adolescents (MIS-C): A systematic review of clinical features and presentation Children and COVID-19 vaccines Evaluation of the BNT162b2 Covid-19 vaccine in children 5 to 11 years of age Não há morte de criança que justifique vacina emergencial Após alta em hospitalizações de crianças nos EUA, médicos defendem vacinas. CNN Brasil Laboratory of Pharmacology and Molecular Chemistry, Department of Biological Chemistry, Regional University of Cariri, Crato, Brazil.