key: cord-0912404-bo425duq authors: Hamad, Abdel-Mohsen M; El-Saka, Hala A title: Is it a bulla or a pneumatocele? date: 2021-01-22 journal: Eur J Cardiothorac Surg DOI: 10.1093/ejcts/ezaa481 sha: 0968c72b8dc99ce4f5fe76a5952855813a51366a doc_id: 912404 cord_uid: bo425duq nan In our patient, we had the opportunity to surgically remove the roof of the air space cyst; and histopathologic examination of the resected material showed thin pieces of parenchymal tissue with significant fibrosis, inflammatory cell infiltration, and marked intra alveolar haemorrhage. This picture is consistent with pneumatocele nature. Previous experience demonstrated that the majority of pneumatocele regress in size and resolve spontaneously [5] . This is not the situation with bullae, which tend to increase in size with time. We think that cystic air spaces that develop during pulmonary infectious processes like COVID-19 should be termed as pneumatoceles rather than bullae. Spontaneous pneumothorax and subpleural bullae in a patient with COVID-19: a 92-day observation Surgical pathology of bullae with and without pneumothorax Pulmonary pneumatocele: pathology and pathogenesis Subpleural emphysema complicating staphylococcal and other pneumonias large-sized neonatal pneumatoceles: the wait-and-see strategy Conflict of interest: none declared.