key: cord-0910969-qf7klg5m
authors: Mungmunpuntipantip, Rujittika; Wiwanitkit, Viroj
title: Pre-vaccination immune response to COVID-19
date: 2021-10-28
journal: Ir J Med Sci
DOI: 10.1007/s11845-021-02822-w
sha: 61d8c7ccf6e60d51c00e890c1f353e2c4e83f34c
doc_id: 910969
cord_uid: qf7klg5m

nan

We would like to share ideas on the publication "Prevaccination immune response to COVID-19 in a population in Northeast Portugal [1] ." Duro et al. concluded that "IgM and IgG displayed a similar initial increase … the identification of previously undiagnosed participants. [1] ." We agree that the pre-vaccination antibody study might be useful. A diagnosis of previous asymptomatic infection can help gather correct epidemiological data. Additionally, the investigation might be useful for determining vaccine efficacy and surveillance of safety of vaccination. In a previous report, immune response to COVID-19 vaccine differs in cases with and without previous COVID-19 [2] . Additionally, a COVID-19 vaccine recipient with previous COVID-19 has a higher blood viscosity after vaccination, which might lead to hyperviscosity-associated adverse effect of vaccination [2] .

Pre-vaccination immune response to COVID-19 in a population in Northeast Portugal

Viscosity after COVID-19 vaccination, hyperviscosity and previous COVID-19