key: cord-0908732-qefsdvj8
authors: Cransac-Miet, Amélie; Zeller, Marianne; Chagué, Frédéric; Faure, Agnès Soudry; Bichat, Florence; Danchin, Nicolas; Boulin, Mathieu; Cottin, Yves
title: Impact of COVID-19 lockdown on lifestyle adherence in stay-at-home patients with chronic coronary syndromes: Towards a time bomb.
date: 2020-09-01
journal: Int J Cardiol
DOI: 10.1016/j.ijcard.2020.08.094
sha: 7d06fc857d1e0b411d459577c9874137b8685c7c
doc_id: 908732
cord_uid: qefsdvj8

BACKGROUND: We aimed to evaluate the impact of coronavirus disease 2019 (COVID-19)-related lockdown on adherence to lifestyle and drug regimens in stay-at-home chronic coronary syndromes patients living in urban and rural areas. METHODS: A cross-sectional population-based study was perfomed in patients with chronic coronary syndromes. A sample of 205 patients was randomly drawn from the RICO (Observatoire des infarctus de Côte d'Or) cohort. Eight trained interviewers collected data by phone interview during week 16 (April 13 to April 19), i.e. 4 weeks after implementation of the French lockdown (start March 17, 2020). RESULTS: Among the 195 patients interviewed (of the 205, 3 had died, 1 declined, 6 lost), mean age was 65.5 ± 11.1 years. Only six patients (3%) reported drug discontinuation, mainly driven by media influence or family members. All 166 (85%) patients taking aspirin continued their prescribed daily intake. Lifestyle rules were less respected since almost half (45%) declared >25% reduction in physical activity, 26% of smokers increased their tobacco consumption by >25%, and 24% of patients increased their body weight > 2 kg. The decrease in physical activity and the increase in smoking were significantly greater in urban patients (P < .05). CONCLUSIONS: The COVID-19-related lockdown had a negative impact on lifestyle in a representative sample of stay-at-home CCS patients.

Qualitative and continuous variables are described using frequency, percentage, and mean (± standard deviation), respectively. The two groups (urban vs rural) were compared using the Chi2 or Fischer exact test for qualitative variables and the Wilcoxon test for continuous variables.

Among the 195 patients interviewed (of the 205, 3 had died, 1 declined, 6 lost), mean age was 65.5 ± 11.1 years. Most were men (61%). All stated they respected lockdown rules. An important proportion declared increasing symptoms as assessed by angina (8%) or nitroglycerin use (2%). Only six patients (3%) reported drug discontinuation, mainly driven by media influence or family members for clopidogrel (n=2), atorvastatin (n=2), bisoprolol (n=1), and for perindopril (n=1). 

ESC Guidelines for the diagnosis and management of chronic coronary syndromes

Coronavirus Disease 2019 (COVID-19) Infection and Renin Angiotensin System Blockers

Adherence to Guideline Medication Recommendations to Prevent Atherosclerotic Cardiovascular Disease Progression Among Adults With Prior Myocardial Infarction

Caring for Patients With Pain During the COVID-19 Pandemic: Consensus Recommendations From an International Expert Panel

Sanchis-Gomar F. Physical inactivity and cardiovascular disease at the time of coronavirus disease 2019 (COVID-19)

The authors thank Philip Bastable for his kind proofreading and Pauline Pistre, Mailis Saint Jalmes and Anthony Carmona for interviews.