key: cord-0899623-yep6dpl1
authors: Patel, Raj H.; Pella, Pablo M.
title: COVID‐19 in a patient with HIV infection
date: 2020-06-03
journal: J Med Virol
DOI: 10.1002/jmv.26049
sha: 568d9a7f6bf6ddd643d8d40120fb8ead99bf3fc4
doc_id: 899623
cord_uid: yep6dpl1

The worldwide pandemic of the novel coronavirus disease 2019 (COVID-19) has raised many challenges and uncertainties regarding disease management and prognosis in immunocompromised patient populations. The concurrence of human immunodeficiency virus (HIV) infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of COVID-19, presents an intriguing problem and only a handful of these cases exist in the literature, despite 37.9 million people living with HIV throughout the world. Previous reports suggest the possibility of a protective factor from standard antiretroviral treatment for HIV patients that could have significant clinical benefits for these patients when co-infected with SARS-CoV-2. HIV patients also generally present with atypical clinical presentation and have a less severe form of COVID-19 than the general population. Here, we present the first case of an HIV positive patient who was diagnosed with COVID-19 in the United States. This article is protected by copyright. All rights reserved.

To the Editor, SARS-CoV-2, the etiological agent responsible for the novel coronavirus disease 2019 (COVID-19) has led to curiosities that have driven the path of drug discovery and research for optimal clinical management, especially in patients with other underlying comorbidities. 1 Patients of older age (>60 years) and with other comorbidities such as hypertension, respiratory disease, cardiovascular disease, diabetes, and chronic kidney disease are found to present with more severe infection and have adverse outcomes. 2 were also proven as an effective course of treatment during the SARS-CoV epidemic. 8 Though there is not enough currently available evidence to argue that PLWH that are receiving standard antiretroviral treatment may be at a lower risk of contracting COVID-19, previous case reports indicate favorable prognosis for these coinfected patients that were already receiving ART. Here, we report a recovered case of SARS-CoV-2 infection in an HIV-positive 58-year-old male, who has been followed by our infectious disease clinic for antiretroviral therapy. with HIV as a factor of increased mortality, however, our patient still recovered without severe symptoms. He was not admitted to the intensive care unit nor did he require mechanical ventilation, and symptoms resolved after a few days of treatment with hydroxychloroquine, azithromycin, and his normal antiretroviral regimen (Table 1) 

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