key: cord-0896780-ufpa9wxy authors: Watanabe, Atsuyuki title: Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: “perceived futility” and potential underestimation of ECMO’s effect date: 2022-04-22 journal: Intensive Care Med DOI: 10.1007/s00134-022-06711-3 sha: f907ee7c64930a957b1f2b546ecfea62da0e6d18 doc_id: 896780 cord_uid: ufpa9wxy nan lower than those included for matching (34.5 vs. 52.7%, p < 0.001). Assuming that not the main text but Table 1 is correct, patients judged as "too severe" received ECMO more frequently and died less frequently. In principle, prespecified protocols do not let us conduct arbitrary analyses after data collection. For this study, however, further analyses including the "too severe" patients will add remarkable value and meaning to the demonstrated results; ECMO could actually have more potential to save patients with severe COVID-19 than it was measured. The clinical benefit of ECMO initiation to severe COVID-19 patients, including those "too severe, " will be of significant interest to frontline providers. Conflicts of interest I have no financial or non-financial competing interests to declare. Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations. Accepted: 19 April 2022 Extracorporeal membrane oxygenation for respiratory failure Extracorporeal membrane oxygenation network organisation and clinical outcomes during the COVID-19 pandemic in greater Paris, France: a multicentre cohort *Correspondence: atsuwatanabe.tuk@gmail.com Division of Hospital Medicine Extracorporeal membrane oxygenation for COVID-19: a systematic review and meta-analysis Extracorporeal membrane oxygenation for severe acute respiratory distress syndrome associated with COVID-19: a retrospective cohort study Survival benefit of extracorporeal membrane oxygenation in severe COVID-19: a multi-centrematched cohort study