key: cord-0893936-unw4ot4l authors: Mugnai, Giacomo; Cavedon, Stefano; Zuin, Marco; Roncon, Loris; Bilato, Claudio title: COVID-19: when more might be less date: 2021-03-31 journal: Nutr Metab Cardiovasc Dis DOI: 10.1016/j.numecd.2021.03.022 sha: 97760574cb403959539909085a5e51cc3f10dacf doc_id: 893936 cord_uid: unw4ot4l nan OVID----19: when more 19: when more 19: when more 19: when more might be might be might be might be less. less. less. less. to the national amount of 81.285 (0.15%) 2 . Finally, as suggested 4 , new mutations of the viral genome found in Veneto as well as in other countries might have made it more contagious and spreadable. Still, Veneto was undoubtedly hit more severely by SARS-CoV-2 infection compared to other Italian regions, overturning the scenario of the first wave of the pandemic. The most probable explanation of the differences between Veneto and the rest of the country was the diverse regimen of restrictions applied. The CoSS (COVID-19 Spread and Severity) Index 5 accurately defines the risk of COVID-19 spread and severity at any given time, in a specific geographic area (low risk <5, intermediate 5-10, high >10) as the ratio between total deaths and number of recovered patients multiplied by the incidence of new regional cases/total regional inhabitants in the last 2 weeks. As the figure shows, on October 20 th the CoSS index Covid-19 in Italy: Lesson from the Veneto region Italian Ministry of Health website. Covid-19 Situation in Italy Report about COVID-19 emergency Zaia: in Veneto quanti contagi? Ma qui facciamo migliaia di tamponi". Corriere della Sera online, 28 th Safety for all: coronavirus disease 2019 pandemic and cardiac surgery: a roadmap to 'phase' 2