key: cord-0893485-aaz2i3th
authors: Huang, Rui; Zhao, Haiyan; Wang, Jian; Yan, Xiaomin; Shao, Huaping; Wu, Chao
title: A family cluster of COVID-19 involving an asymptomatic case with persistently positive SARS-CoV-2 in anal swabs
date: 2020-05-16
journal: Travel Med Infect Dis
DOI: 10.1016/j.tmaid.2020.101745
sha: 0549648b772f68d648c0e37575f167331f53f6c9
doc_id: 893485
cord_uid: aaz2i3th

nan

To the Editor, In December 2019, coronavirus disease 2019 (COVID-19) emerged in Wuhan, China and spread throughout the world rapidly [1, 2] . Several studies have described the epidemiologic and clinical characteristics of COVID-19 patients [1] [2] [3] . The clinical spectrum of COVID-19 varies from mild to critically illness [3] .

We report a family cluster of two patients with COVID-19 involving an asymptomatic case with normal blood routine tests and chest CT images but positive of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) nucleic acid in swab samples, especially in anal swab samples. 

A Novel Coronavirus from Patients with Pneumonia in China

Taking the Right Measures to Control COVID-19

Clinical Characteristics of Coronavirus Disease 2019 in China

World Health Organization. Laboratory diagnostics for novel coronavirus

Anal swab findings in an infant with COVID-19

Detection of SARS-CoV-2 by RT-PCR in anal from patients who have recovered from coronavirus disease 2019

Detection and analysis of nucleic acid in various biological samples of COVID-19 patients

Molecular and serological investigation of 2019-nCoV infected patients: implication of multiple shedding routes